term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Proximal tubulopathy
8
28
2.851723
0.004348
Q16134,Q9NPL8,Q96CU9,Q8IUX1,P00403,Q7LG56,O43676,Q86Y39
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
35,135,139,92,243,220,28,62
1507,28,1975,777,689,977,1244,243,503,2563,2820,3161,2533,3000,1079,1483,35,220,62,92,822,1451,139,1965,135,533,994,270
-0.11183646061143145,3.249069666218409,-0.3200108532156369,0.4392916383060073,0.5311657302429517,0.23490508817494482,0.039393905728626555,1.554976405224503,0.8125216901520601,-0.591518313499491,-0.72282678915474,-1.115678167758971,-0.5730062666389593,-0.8767186560343143,0.154267746052456,-0.09483094105616925,3.1554684246520415,1.6922472673617857,2.6926544679277815,2.418740417134722,0.3927828796273702,-0.07787664700247479,2.1076193115504527,-0.3023663071850197,2.119039208483976,0.7835641129412465,0.23490508817494482,1.4400757456470827
3,329
Glycosylation
23
50
2.851408
0.004353
P15291,Q14165,O43909,O43505,Q9BXS4,P46977,P26572,Q9H9E3,Q9BT22,P04844,Q8TCJ2,O60476,O75503,Q9H9S5,Q6ZXV5,O60568,P04062,Q86YN1,Q10472,Q96JB2,P04843,O15118,Q9HC07
Processes and pathways
GO Biological process
msigdb_gobp
756,761,401,408,153,283,546,423,300,557,563,65,200,601,340,720,89,103,231,369,626,253,126
2985,253,2289,408,401,65,1038,720,1103,840,200,1342,89,626,557,756,546,981,283,3290,1948,1562,1023,914,984,231,2798,761,1081,986,340,1174,2034,103,563,369,2509,2745,300,153,1236,1313,423,601,126,1921,2518,1462,1318,791
-0.8572521419813814,1.5169403833744672,-0.46318920134873065,1.0111193241132475,1.02503756555061,2.6410312412580748,0.18666184318592197,0.4854172249404048,0.13800033403990275,0.36156109284692456,1.753534262581889,-0.02731813899443857,2.4295325225007747,0.6215551504261415,0.725194197877662,0.454709104760018,0.7544554622052062,0.23490508817494482,1.4142154574761407,-1.7838503924546287,-0.3023663071850197,-0.1288935074639876,0.20278905267534755,0.298590741936191,0.23490508817494482,1.6177947509504282,-0.7038809140344804,0.454709104760018,0.154267746052456,0.23490508817494482,1.2028754731019637,0.10532345566594865,-0.3377107639133768,2.342595734045094,0.725194197877662,1.107823807425468,-0.554554622770862,-0.6661782994152631,1.3359030458402381,1.9920988307239456,0.055948952378408766,0.006136821954560253,0.9831780141194827,0.6662075505020892,2.1983218430127764,-0.2847767900895569,-0.554554622770862,-0.07787664700247479,0.006136821954560253,0.4392916383060073
3,329
Protein transmembrane transporter activity
8
10
2.849217
0.004383
Q9NS69,Q99595,O14925,P61619,Q9UGP8,P49755,Q07820,Q15388
Functions
GO Molecular function
msigdb_gomf
0,4,68,11,176,435,436,381
68,1409,510,435,11,436,381,4,0,176
2.6202449005730086,-0.06097327927337434,0.7980616903860556,0.941001406390935,3.60814852819791,0.941001406390935,1.066584662292758,3.944919490586592,4.436105046391561,1.8860190523984428
3,329
Sphingolipid biosynthetic process
12
18
2.849132
0.004384
Q13131,O15269,O15270,Q9NRA0,Q06136,Q96G23,Q16739,Q9P035,P04062,O95470,Q53H12,Q13510
Processes and pathways
GO Biological process
msigdb_gobp
482,197,543,555,362,205,143,179,89,60,568,63
197,543,60,89,1321,2565,2959,362,482,63,143,568,205,634,555,1220,179,1126
1.753534262581889,0.7544554622052062,2.743795341242332,2.4295325225007747,-0.010565780915623473,-0.591518313499491,-0.8185184586058571,1.1351476669380705,0.8556781055702337,2.661738980107334,2.0732168219235088,0.7105058479496481,1.7413311109795258,0.6215551504261415,0.7398440039046587,0.07245537536615151,1.8741054980652416,0.13800033403990275
3,329
Predicted secreted proteins
15
52
2.84906
0.004385
O60888,P80303,O94919,Q15165,Q9HB40,P84157,Q9NZ08,Q9BUR5,Q9BTY2,Q8N128,P43490,Q8WUJ1,Q02818,O75718,Q9UM22
Functions
Protein Atlas Protein class
protein_atlas_protein_class
286,2,34,196,69,99,203,80,279,208,113,152,25,158,95
856,720,286,158,1978,34,2609,1319,2094,2722,1981,1245,1470,1435,480,592,1104,2138,2727,1105,2999,113,2262,2192,1852,983,2,3322,99,25,1634,413,2500,1705,2577,196,208,3308,152,766,1397,825,850,279,80,2283,601,69,203,95,459,315
0.3458847108749264,0.4854172249404048,1.388233986679566,1.9452039775495766,-0.3200108532156369,3.1649012792568008,-0.6100911490136454,-0.010565780915623473,-0.37327803753599764,-0.6661782994152631,-0.3200108532156369,0.039393905728626555,-0.09483094105616925,-0.07787664700247479,0.8556781055702337,0.6662075505020892,0.13800033403990275,-0.3911460873340927,-0.6661782994152631,0.13800033403990275,-0.8767186560343143,2.2653806298271815,-0.44509207637698556,-0.40907087562127437,-0.2672419692131069,0.23490508817494482,4.1922085811082255,-5.125910344715131,2.3535384052387704,3.2860641032927025,-0.16316340352062567,0.9971661971089063,-0.554554622770862,-0.1976430971357671,-0.591518313499491,1.765710523010228,1.7291009524876284,-2.260443797158469,2.0037604794882196,0.454709104760018,-0.0441205412804845,0.3927828796273702,0.36156109284692456,1.4271606806581227,2.525717907582542,-0.44509207637698556,0.6662075505020892,2.6202449005730086,1.753534262581889,2.4079270495189844,0.8985030393464208,1.3095513119692044
3,329
Frequent falls
14
43
2.848842
0.004388
O95140,Q7RTS9,Q9NZJ7,O43681,Q9H9S5,Q7LG56,Q9NR77,P07602,P53007,P04062,P12235,O43819,Q13510,P00846
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
357,428,210,521,601,220,313,54,497,89,244,470,63,159
521,470,840,1187,357,159,89,1042,54,592,244,873,1699,1439,1044,1804,1891,497,2456,2300,1479,2150,1023,63,2306,2830,2694,1740,1120,220,428,1396,1824,2773,2745,601,1613,313,2041,1503,210,1462,1318
0.7835641129412465,0.869989669830986,0.36156109284692456,0.08891345160359984,1.148759408279367,1.9452039775495766,2.4295325225007747,0.18666184318592197,2.884496729742283,0.6662075505020892,1.554976405224503,0.3301643523967748,-0.1976430971357671,-0.07787664700247479,0.18666184318592197,-0.24976151481950415,-0.2847767900895569,0.8269443011610067,-0.5361629998579605,-0.46318920134873065,-0.09483094105616925,-0.3911460873340927,0.20278905267534755,2.661738980107334,-0.46318920134873065,-0.72282678915474,-0.6474207470427343,-0.2149624012246617,0.13800033403990275,1.6922472673617857,0.9691546034871085,-0.0441205412804845,-0.24976151481950415,-0.6849982202518423,-0.6661782994152631,0.6662075505020892,-0.1460023860587023,1.3095513119692044,-0.3377107639133768,-0.09483094105616925,1.7291009524876284,-0.07787664700247479,0.006136821954560253
3,329
Glycerolipid biosynthetic process
17
46
2.848262
0.004396
P35790,P42356,Q5H8A4,Q8NCC3,Q9UG56,Q9NX62,Q96N66,P48651,Q9HCL2,Q9NPH0,Q8WTV0,Q8NF37,Q01469,Q9Y2B2,O15228,Q92604,O95674
Processes and pathways
GO Biological process
msigdb_gobp
353,513,133,294,100,360,265,330,364,140,141,494,499,337,430,278,181
2891,1430,430,1103,1015,181,3103,2092,3079,2052,1846,1440,353,513,330,2068,499,1483,1353,594,1860,2115,133,744,294,2311,494,141,1196,278,809,1359,700,265,3205,770,2593,1070,973,364,140,532,360,1286,100,337
-0.7800476461635257,-0.07787664700247479,0.9550957923021207,0.13800033403990275,0.20278905267534755,1.8502009604159466,-1.0148869538509337,-0.37327803753599764,-0.9750659227068427,-0.35546637806239667,-0.2672419692131069,-0.07787664700247479,1.162337902585846,0.7980616903860556,1.229737143732253,-0.35546637806239667,0.8269443011610067,-0.09483094105616925,-0.02731813899443857,0.6662075505020892,-0.2672419692131069,-0.37327803753599764,2.1418081770228548,0.4700842251171112,1.362130224201825,-0.46318920134873065,0.8413297109269698,2.0961756789829376,0.08891345160359984,1.4271606806581227,0.40832875583933903,-0.02731813899443857,0.5311657302429517,1.4658159453703792,-1.218288580612294,0.454709104760018,-0.591518313499491,0.1704881613421552,0.2508944256563078,1.1351476669380705,2.1076193115504527,0.7835641129412465,1.148759408279367,0.022789956142157834,2.3535384052387704,1.2163225435836422
3,329
Intracellular protein transmembrane transport
10
21
2.845567
0.004433
Q15629,Q8N4Q1,Q99595,O14925,O75381,P61619,O95831,Q9UGP8,O75298,Q15388
Processes and pathways
GO Biological process
msigdb_gobp
32,290,4,68,199,11,238,176,187,381
68,390,187,199,1409,238,510,2405,1298,2263,2880,11,381,32,620,3300,290,657,4,1577,176
2.6202449005730086,1.0527700672687526,1.8261924564729928,1.753534262581889,-0.06097327927337434,1.5675972372369518,0.7980616903860556,-0.5178310194419322,0.006136821954560253,-0.44509207637698556,-0.7609097368252487,3.60814852819791,1.066584662292758,3.211822037822721,0.636478968201094,-2.017198142965321,1.3751974618052982,0.5915874267986064,3.944919490586592,-0.1288935074639876,1.8860190523984428
3,329
Secretory granule membrane
23
69
2.843095
0.004468
Q92542,Q96JJ7,Q07065,O95721,P35613,O00264,P49755,P07602,P30519,P10321,P11279,Q9NV96,P42785,Q9NZJ7,Q93050,Q15363,Q08722,Q99829,Q8NF37,Q01469,Q969Q5,Q5T9A4,P27105
Localization
GO Cellular component
msigdb_gocc
256,264,142,522,150,172,435,54,57,450,451,458,204,210,209,464,215,483,494,499,249,372,254
1970,172,3125,2782,1466,2559,3114,2892,1187,3198,2848,522,902,54,545,450,451,1802,1411,756,2971,1246,1730,254,57,1264,2688,150,981,204,2223,435,1021,1077,863,3014,982,630,1480,2105,1810,1703,1302,499,142,215,881,761,843,464,2232,372,1151,494,1681,256,209,249,264,483,1494,1236,926,458,210,1126,899,603,2324
-0.3200108532156369,1.8860190523984428,-1.054989153775941,-0.7038809140344804,-0.09483094105616925,-0.591518313499491,-1.0349026666953354,-0.7800476461635257,0.08891345160359984,-1.1976178933685362,-0.741836257964152,0.7835641129412465,0.298590741936191,2.884496729742283,0.7544554622052062,0.9127052073021598,0.9127052073021598,-0.24976151481950415,-0.06097327927337434,0.454709104760018,-0.8378522233550003,0.039393905728626555,-0.2149624012246617,1.5169403833744672,2.834660963208476,0.022789956142157834,-0.6474207470427343,2.0037604794882196,0.23490508817494482,1.7413311109795258,-0.42705275376542584,0.941001406390935,0.20278905267534755,0.154267746052456,0.3458847108749264,-0.896252211455973,0.23490508817494482,0.6215551504261415,-0.09483094105616925,-0.37327803753599764,-0.24976151481950415,-0.1976430971357671,0.006136821954560253,0.8269443011610067,2.0847082146706413,1.7045591482602571,0.3301643523967748,0.454709104760018,0.36156109284692456,0.8842645870828738,-0.42705275376542584,1.0941113685623118,0.12168565981800496,0.8413297109269698,-0.18037686968631964,1.5169403833744672,1.7291009524876284,1.554976405224503,1.4658159453703792,0.8556781055702337,-0.09483094105616925,0.055948952378408766,0.298590741936191,0.8985030393464208,1.7291009524876284,0.13800033403990275,0.3143997769058518,0.6662075505020892,-0.46318920134873065
3,329
Sensory perception of light stimulus
7
19
2.84219
0.00448
Q9NWW5,O43924,Q9H6K4,P50897,Q99797,O76024,O60313
Processes and pathways
GO Biological process
msigdb_gobp
97,107,46,16,115,250,124
107,124,2134,250,2447,592,16,818,1349,1484,358,2672,1333,115,1827,2513,46,97,1927
2.3206447765853273,2.209555246837717,-0.3911460873340927,1.5423267379676606,-0.5361629998579605,0.6662075505020892,3.377464146466878,0.3927828796273702,-0.02731813899443857,-0.09483094105616925,1.148759408279367,-0.628725162512366,-0.010565780915623473,2.254260805481034,-0.24976151481950415,-0.554554622770862,3.02166491683524,2.3753585548204437,-0.2847767900895569
3,329
Sensorimotor neuropathy
14
33
2.84193
0.004484
P03915,P07196,O15270,Q5KU26,O95831,Q9NZJ7,O60313,P05023,P07602,Q9NR77,P00403,Q7LG56,Q9Y2R0,P00846
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
503,326,543,363,238,210,124,213,54,313,243,220,30,159
1721,543,124,960,238,243,159,503,213,326,54,906,2614,2874,1804,1165,1891,932,2456,2300,1522,783,363,220,1005,988,3008,313,589,3136,210,30,1162
-0.2149624012246617,0.7544554622052062,2.209555246837717,0.2508944256563078,1.5675972372369518,1.554976405224503,1.9452039775495766,0.8125216901520601,1.7045591482602571,1.243119425650111,2.884496729742283,0.298590741936191,-0.6100911490136454,-0.7609097368252487,-0.24976151481950415,0.10532345566594865,-0.2847767900895569,0.28273700304120136,-0.5361629998579605,-0.46318920134873065,-0.11183646061143145,0.4392916383060073,1.1351476669380705,1.6922472673617857,0.2188700487407775,0.23490508817494482,-0.8767186560343143,1.3095513119692044,0.6810127242035948,-1.054989153775941,1.7291009524876284,3.2304777113167784,0.12168565981800496
3,329
Macromolecule transmembrane transporter activity
8
11
2.841688
0.004488
Q9NS69,Q99595,O14925,P61619,Q9UGP8,P49755,Q07820,Q15388
Functions
GO Molecular function
msigdb_gomf
0,4,68,11,176,435,436,381
68,1409,510,435,963,11,436,381,4,0,176
2.6202449005730086,-0.06097327927337434,0.7980616903860556,0.941001406390935,0.2508944256563078,3.60814852819791,0.941001406390935,1.066584662292758,3.944919490586592,4.436105046391561,1.8860190523984428
3,329
Apoptosis
31
124
2.839604
0.004517
Q9BXK5,O95197,Q6NUQ4,Q13177,Q9UHX1,Q9Y371,Q9UBK9,Q96KA5,P12236,Q9NR28,Q96A26,O60566,Q16513,Q9H3K2,P21796,Q15041,Q07820,O95470,Q9UDX5,P09601,Q9NZJ7,P46379,P51572,O14737,Q9P0J0,Q12981,O95140,P10909,Q13043,O95831,O60313
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
260,6,262,529,136,399,280,147,402,149,27,535,422,161,37,38,436,60,188,76,210,344,345,469,225,355,357,480,489,238,124
2483,1585,1428,469,2289,1378,2133,124,1934,535,840,857,2177,357,6,60,978,238,1055,2092,2018,2137,1663,76,480,402,3061,3080,2821,37,1845,2873,1513,1668,2022,672,1768,2026,947,344,1943,345,1142,1629,3290,1703,2067,1811,694,1443,2959,1634,727,436,1303,2500,355,489,1388,2385,529,2422,1812,1706,1230,2736,1950,1813,619,38,844,422,1566,2156,2157,262,2274,2910,1863,1195,2238,1277,1785,1397,27,2164,935,1278,1008,1787,922,147,571,2126,260,2777,991,3176,2919,894,161,895,1714,2596,1614,149,2246,953,210,225,1072,280,188,3236,136,2751,2679,3042,1036,399,774,1073,1836,1928
-0.554554622770862,-0.1460023860587023,-0.07787664700247479,0.869989669830986,-0.46318920134873065,-0.0441205412804845,-0.3911460873340927,2.209555246837717,-0.3023663071850197,0.7690287674741151,0.36156109284692456,0.3458847108749264,-0.40907087562127437,1.148759408279367,3.86267115397857,2.743795341242332,0.23490508817494482,1.5675972372369518,0.1704881613421552,-0.37327803753599764,-0.3377107639133768,-0.3911460873340927,-0.18037686968631964,2.546865254937197,0.8556781055702337,1.02503756555061,-0.9552596524756897,-0.9750659227068427,-0.72282678915474,3.1175728322198215,-0.2672419692131069,-0.7609097368252487,-0.11183646061143145,-0.18037686968631964,-0.3377107639133768,0.561458187161226,-0.2323351001172288,-0.3377107639133768,0.2668383137721389,1.1893957791189034,-0.3023663071850197,1.1893957791189034,0.12168565981800496,-0.16316340352062567,-1.7838503924546287,-0.1976430971357671,-0.35546637806239667,-0.24976151481950415,0.5311657302429517,-0.07787664700247479,-0.8185184586058571,-0.16316340352062567,0.4854172249404048,0.941001406390935,0.006136821954560253,-0.554554622770862,1.162337902585846,0.8413297109269698,-0.0441205412804845,-0.49955830659898626,0.7835641129412465,-0.5178310194419322,-0.24976151481950415,-0.1976430971357671,0.055948952378408766,-0.6661782994152631,-0.3023663071850197,-0.24976151481950415,0.636478968201094,3.108057612146517,0.36156109284692456,0.9831780141194827,-0.1288935074639876,-0.3911460873340927,-0.3911460873340927,1.4786413499917181,-0.44509207637698556,-0.7800476461635257,-0.2672419692131069,0.08891345160359984,-0.42705275376542584,0.022789956142157834,-0.2323351001172288,-0.0441205412804845,3.2583418811704092,-0.3911460873340927,0.28273700304120136,0.022789956142157834,0.2188700487407775,-0.2323351001172288,0.298590741936191,2.0270100122467594,0.7105058479496481,-0.37327803753599764,1.4914371362101484,-0.6849982202518423,0.23490508817494482,-1.1360526844862961,-0.7800476461635257,0.3143997769058518,1.9452039775495766,0.3143997769058518,-0.1976430971357671,-0.591518313499491,-0.1460023860587023,2.0153975063698106,-0.42705275376542584,0.2668383137721389,1.7291009524876284,1.642723772750052,0.1704881613421552,1.4271606806581227,1.8261924564729928,-1.3651237435960266,2.119039208483976,-0.6661782994152631,-0.628725162512366,-0.9158532586395145,0.20278905267534755,1.0389210906111273,0.454709104760018,0.1704881613421552,-0.24976151481950415,-0.2847767900895569
3,329
Molecular transducer activity
16
37
2.833516
0.004604
Q15629,Q99720,Q9NRA0,Q99523,O15173,P30536,Q8WTV0,Q5KU26,Q9UGP8,Q9BUN8,P20645,Q08722,O15118,P15260,Q14108,Q9Y6I9
Functions
GO Molecular function
msigdb_gomf
32,67,555,266,43,329,141,363,176,81,627,215,253,411,189,519
253,43,1187,3198,2609,999,1553,1292,1802,411,627,329,2534,931,1633,3093,215,1353,1705,189,32,967,1778,363,3147,141,3166,657,266,67,81,555,2246,1923,1094,176,519
1.5169403833744672,3.050614833480472,0.08891345160359984,-1.1976178933685362,-0.6100911490136454,0.2188700487407775,-0.1288935074639876,0.006136821954560253,-0.24976151481950415,0.9971661971089063,0.6215551504261415,1.229737143732253,-0.5730062666389593,0.28273700304120136,-0.16316340352062567,-0.9949415319801789,1.7045591482602571,-0.02731813899443857,-0.1976430971357671,1.8141489416949947,3.211822037822721,0.2508944256563078,-0.2323351001172288,1.1351476669380705,-1.0751469033081054,2.0961756789829376,-1.115678167758971,0.5915874267986064,1.4658159453703792,2.6306479323828786,2.504488675343527,0.7398440039046587,-0.42705275376542584,-0.2847767900895569,0.154267746052456,1.8860190523984428,0.7980616903860556
3,329
Sphingolipid metabolism
7
10
2.829338
0.004664
P17900,O15269,Q16739,P07602,P04062,O95470,Q13510
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
66,197,143,54,89,60,63
197,543,60,89,54,66,362,63,143,939
1.753534262581889,0.7544554622052062,2.743795341242332,2.4295325225007747,2.884496729742283,2.6306479323828786,1.1351476669380705,2.661738980107334,2.0732168219235088,0.28273700304120136
3,329
Azurophil granule
26
72
2.825649
0.004718
Q92542,O15400,Q07065,O95721,O43681,Q9BTY2,P15586,P53634,Q92820,P06865,O00754,P16278,P06280,P07602,P17900,P11279,Q9NV96,P42785,P10619,Q9NZJ7,Q99829,P04066,Q01469,P08236,Q8NF37,P27105
Localization
GO Cellular component
msigdb_gocc
256,509,142,522,521,279,536,412,414,287,295,298,301,54,66,451,458,204,77,210,483,110,499,367,494,254
1970,1618,856,295,509,521,2559,3114,522,2930,110,301,287,1981,2095,54,1622,367,545,77,2953,451,1411,756,536,298,66,2101,254,1513,2989,981,204,2900,2762,2617,1021,863,2791,412,1894,2456,2457,983,2378,1482,499,1858,2959,142,1522,2830,3200,1151,2036,494,256,414,646,2703,1157,483,1335,279,1789,1236,753,458,2440,210,1126,2713
-0.3200108532156369,-0.16316340352062567,0.3458847108749264,1.3490321328683648,0.7980616903860556,0.7835641129412465,-0.591518313499491,-1.0349026666953354,0.7835641129412465,-0.7992504105201905,2.287553021209273,1.322742820180127,1.388233986679566,-0.3200108532156369,-0.37327803753599764,2.884496729742283,-0.16316340352062567,1.107823807425468,0.7544554622052062,2.546865254937197,-0.8185184586058571,0.9127052073021598,-0.06097327927337434,0.454709104760018,0.7690287674741151,1.3359030458402381,2.6306479323828786,-0.37327803753599764,1.5169403833744672,-0.11183646061143145,-0.8572521419813814,0.23490508817494482,1.7413311109795258,-0.7800476461635257,-0.6849982202518423,-0.6100911490136454,0.20278905267534755,0.3458847108749264,-0.7038809140344804,0.9971661971089063,-0.2847767900895569,-0.5361629998579605,-0.5361629998579605,0.23490508817494482,-0.49955830659898626,-0.09483094105616925,0.8269443011610067,-0.2672419692131069,-0.8185184586058571,2.0847082146706413,-0.11183646061143145,-0.72282678915474,-1.1976178933685362,0.12168565981800496,-0.3377107639133768,0.8413297109269698,1.5169403833744672,0.9971661971089063,0.6065913728144292,-0.6474207470427343,0.12168565981800496,0.8556781055702337,-0.010565780915623473,1.4271606806581227,-0.2323351001172288,0.055948952378408766,0.4700842251171112,0.8985030393464208,-0.5178310194419322,1.7291009524876284,0.13800033403990275,-0.6474207470427343
3,329
Cellular ion homeostasis
28
86
2.822257
0.004769
P50897,P0DP25,Q16891,Q92544,P0CG08,P20020,P16615,Q96A33,Q8N511,P14625,P55011,O75503,P09601,Q93050,P05023,P51572,O43819,Q9NWW5,Q9Y487,Q9HD20,Q9Y639,O75880,Q8NEW0,P78417,O95202,O76024,P51790,Q9HC07
Processes and pathways
GO Biological process
msigdb_gobp
16,523,274,539,271,282,173,175,306,434,441,200,76,209,213,345,470,97,226,105,236,237,112,376,116,250,379,126
3059,2949,2400,470,2782,721,1431,200,1187,237,3138,250,116,2969,1319,213,830,903,1622,2970,1435,76,271,523,2998,2293,434,173,1937,3201,282,3306,2873,3062,2785,1322,1513,1264,2188,947,16,1077,345,379,2145,910,441,640,537,376,1811,2540,727,1048,2626,1061,274,2505,645,306,623,951,112,653,539,209,175,767,1787,2745,848,2636,2355,126,105,896,97,1462,2083,887,718,774,226,1162,236,2865
-0.9552596524756897,-0.8185184586058571,-0.5178310194419322,0.869989669830986,-0.7038809140344804,0.4854172249404048,-0.07787664700247479,1.753534262581889,0.08891345160359984,1.5675972372369518,-1.0751469033081054,1.5423267379676606,2.243118444252658,-0.8378522233550003,-0.010565780915623473,1.7045591482602571,0.37719373688093016,0.298590741936191,-0.16316340352062567,-0.8378522233550003,-0.07787664700247479,2.546865254937197,1.4271606806581227,0.7835641129412465,-0.8767186560343143,-0.46318920134873065,0.941001406390935,1.8860190523984428,-0.3023663071850197,-1.218288580612294,1.4142154574761407,-2.2109635235386484,-0.7609097368252487,-0.9552596524756897,-0.7038809140344804,-0.010565780915623473,-0.11183646061143145,0.022789956142157834,-0.40907087562127437,0.2668383137721389,3.377464146466878,0.154267746052456,1.1893957791189034,1.066584662292758,-0.3911460873340927,0.298590741936191,0.9268712703037668,0.6065913728144292,0.7690287674741151,1.0803650412592236,-0.24976151481950415,-0.5730062666389593,0.4854172249404048,0.18666184318592197,-0.6100911490136454,0.1704881613421552,1.4271606806581227,-0.554554622770862,0.6065913728144292,1.322742820180127,0.636478968201094,0.2668383137721389,2.276478005753956,0.5915874267986064,0.7690287674741151,1.7291009524876284,1.8860190523984428,0.454709104760018,-0.2323351001172288,-0.6661782994152631,0.36156109284692456,-0.6100911490136454,-0.4813444898962475,2.1983218430127764,2.342595734045094,0.3143997769058518,2.3753585548204437,-0.07787664700247479,-0.35546637806239667,0.3301643523967748,0.5007083280125337,0.454709104760018,1.642723772750052,0.12168565981800496,1.5801893615353702,-0.741836257964152
3,329
Glycerophospholipid metabolism
9
14
2.819928
0.004803
P35790,Q9UG56,Q8NCC3,Q96N66,P48651,Q9HCL2,O15228,Q92604,O95674
Processes and pathways
KEGG Pathways
msigdb_kegg
353,100,294,265,330,364,430,278,181
1430,430,2049,181,2092,353,1166,330,294,494,278,265,364,100
-0.07787664700247479,0.9550957923021207,-0.35546637806239667,1.8502009604159466,-0.37327803753599764,1.162337902585846,0.10532345566594865,1.229737143732253,1.362130224201825,0.8413297109269698,1.4271606806581227,1.4658159453703792,1.1351476669380705,2.3535384052387704
3,329
Abnormal enchondral ossification
13
30
2.818615
0.004823
P38435,Q9UG56,Q9Y619,O00116,O75381,Q15125,O96028,P40855,P08236,O43909,O95202,Q14739,P10644
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
96,100,101,415,199,233,268,299,367,401,116,251,29
415,401,3101,199,116,268,367,29,3028,1381,96,299,1298,2880,1353,2338,251,2388,233,1488,3018,428,3053,610,2509,1796,552,100,2814,101
0.9831780141194827,1.02503756555061,-1.0148869538509337,1.753534262581889,2.243118444252658,1.4529607887524738,1.107823807425468,3.249069666218409,-0.9158532586395145,-0.0441205412804845,2.3970923380516806,1.3359030458402381,0.006136821954560253,-0.7609097368252487,-0.02731813899443857,-0.4813444898962475,1.5423267379676606,-0.49955830659898626,1.5927529048138849,-0.09483094105616925,-0.896252211455973,0.9691546034871085,-0.935522252488236,0.6513630331017662,-0.554554622770862,-0.2323351001172288,0.7544554622052062,2.3535384052387704,-0.7038809140344804,2.3535384052387704
3,329
Organelle membrane contact site
10
16
2.808417
0.004979
O95772,P27824,O96008,O43865,Q96N66,Q96S66,Q5XKP0,Q9Y320,P51572,Q15388
Localization
GO Cellular component
msigdb_gocc
163,512,510,478,265,202,79,476,345,381
1099,478,1407,163,510,512,345,381,79,951,1681,265,202,2593,532,476
0.13800033403990275,0.8556781055702337,-0.06097327927337434,1.9334176844006021,0.7980616903860556,0.7980616903860556,1.1893957791189034,1.066584662292758,2.525717907582542,0.2668383137721389,-0.18037686968631964,1.4658159453703792,1.753534262581889,-0.591518313499491,0.7835641129412465,0.869989669830986
3,329
Golgi apparatus subcompartment
29
94
2.802458
0.005071
Q7Z6M1,Q99523,P0CG08,Q9BXS4,Q9NPR9,Q8NBN3,Q9H9E3,O43752,Q14789,Q92614,Q9H4A6,P53365,Q9BSR8,Q15363,O00461,Q9BZG1,O15127,Q10713,P40616,P04062,Q96A57,P51572,Q10472,Q9NX62,Q9H4A5,Q96JB2,P61026,P20645,Q9HC07
Localization
GO Cellular component
msigdb_gocc
127,266,271,153,24,31,423,167,561,444,317,455,333,464,82,474,86,594,593,89,90,345,231,360,624,369,630,627,126
2891,82,799,86,2364,167,2088,720,1203,1243,2892,89,1056,2330,271,1802,756,1730,627,3028,2565,3081,593,1805,1808,1227,2261,345,863,455,2225,3248,630,1480,1810,1948,2991,1483,780,914,984,231,1900,594,806,1081,561,2626,464,986,1148,1271,1064,644,127,1233,1251,31,971,2237,2806,1066,444,90,369,2509,266,2704,3149,989,333,1070,1538,153,1494,474,1689,624,317,423,126,24,1614,360,1220,701,2678,1221,955,1544,2206,2779,2399,2323
-0.7800476461635257,2.4831769394602983,0.40832875583933903,2.451053270581627,-0.49955830659898626,1.9216061509487739,-0.37327803753599764,0.4854172249404048,0.07245537536615151,0.039393905728626555,-0.7800476461635257,2.4295325225007747,0.1704881613421552,-0.4813444898962475,1.4271606806581227,-0.24976151481950415,0.454709104760018,-0.2149624012246617,0.6215551504261415,-0.9158532586395145,-0.591518313499491,-0.9750659227068427,0.6662075505020892,-0.24976151481950415,-0.24976151481950415,0.055948952378408766,-0.44509207637698556,1.1893957791189034,0.3458847108749264,0.8985030393464208,-0.42705275376542584,-1.4077812643017102,0.6215551504261415,-0.09483094105616925,-0.24976151481950415,-0.3023663071850197,-0.8572521419813814,-0.09483094105616925,0.4392916383060073,0.298590741936191,0.23490508817494482,1.6177947509504282,-0.2847767900895569,0.6662075505020892,0.40832875583933903,0.154267746052456,0.725194197877662,-0.6100911490136454,0.8842645870828738,0.23490508817494482,0.12168565981800496,0.022789956142157834,0.1704881613421552,0.6065913728144292,2.1757859825399093,0.055948952378408766,0.039393905728626555,3.2211578659190487,0.2508944256563078,-0.42705275376542584,-0.7038809140344804,0.1704881613421552,0.9268712703037668,2.4295325225007747,1.107823807425468,-0.554554622770862,1.4658159453703792,-0.6474207470427343,-1.0751469033081054,0.23490508817494482,1.229737143732253,0.1704881613421552,-0.11183646061143145,1.9920988307239456,-0.09483094105616925,0.869989669830986,-0.18037686968631964,0.636478968201094,1.2963283762981763,0.9831780141194827,2.1983218430127764,3.295273542502997,-0.1460023860587023,1.148759408279367,0.07245537536615151,0.5311657302429517,-0.628725162512366,0.07245537536615151,0.2668383137721389,-0.11183646061143145,-0.40907087562127437,-0.6849982202518423,-0.49955830659898626,-0.46318920134873065
3,329
Glycoprotein biosynthetic process
25
55
2.795644
0.00518
P15291,Q92542,Q14165,O43909,O43505,Q9BXS4,P46977,P26572,Q9BT22,P04844,Q8TCJ2,Q9H4A6,Q8NCH0,O60476,Q9H9S5,Q7LGA3,Q6ZXV5,O60568,Q86YN1,Q10472,Q99805,Q96JB2,P04843,O15118,Q9HC07
Processes and pathways
GO Biological process
msigdb_gobp
756,256,761,401,408,153,283,546,300,557,563,317,61,65,601,211,340,720,103,231,634,369,626,253,126
2985,838,253,2289,408,401,65,1038,720,2485,1103,840,1342,626,557,756,546,1886,930,981,283,3290,1948,1562,1023,914,984,231,2798,761,986,340,211,1174,2034,103,61,563,256,369,2509,2745,634,300,153,1236,1313,317,601,126,2477,2518,1462,1318,791
-0.8572521419813814,0.36156109284692456,1.5169403833744672,-0.46318920134873065,1.0111193241132475,1.02503756555061,2.6410312412580748,0.18666184318592197,0.4854172249404048,-0.554554622770862,0.13800033403990275,0.36156109284692456,-0.02731813899443857,0.6215551504261415,0.725194197877662,0.454709104760018,0.7544554622052062,-0.2847767900895569,0.28273700304120136,0.23490508817494482,1.4142154574761407,-1.7838503924546287,-0.3023663071850197,-0.1288935074639876,0.20278905267534755,0.298590741936191,0.23490508817494482,1.6177947509504282,-0.7038809140344804,0.454709104760018,0.23490508817494482,1.2028754731019637,1.7168436706493653,0.10532345566594865,-0.3377107639133768,2.342595734045094,2.7336053345192104,0.725194197877662,1.5169403833744672,1.107823807425468,-0.554554622770862,-0.6661782994152631,0.6215551504261415,1.3359030458402381,1.9920988307239456,0.055948952378408766,0.006136821954560253,1.2963283762981763,0.6662075505020892,2.1983218430127764,-0.5361629998579605,-0.554554622770862,-0.07787664700247479,0.006136821954560253,0.4392916383060073
3,329
Glycoside hydrolase superfamily [IPR017853]
7
16
2.795218
0.005186
P16278,P06280,P04066,Q9BTY2,P54802,P04062,P06865
Sequence
InterPro Superfamily
interpro_homologous_superfamily
298,301,110,279,248,89,287
1038,89,110,301,287,1622,1189,367,545,298,1848,248,1352,1990,279,1538
0.18666184318592197,2.4295325225007747,2.287553021209273,1.322742820180127,1.388233986679566,-0.16316340352062567,0.08891345160359984,1.107823807425468,0.7544554622052062,1.3359030458402381,-0.2672419692131069,1.554976405224503,-0.02731813899443857,-0.3200108532156369,1.4271606806581227,-0.11183646061143145
3,329
Abnormal tissue metabolite concentration
7
14
2.795067
0.005189
P17900,O75381,P40855,Q9NZJ7,P07602,Q5T8D3,P06865
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
66,199,299,210,54,252,287
521,199,301,287,54,1622,66,299,1298,932,252,2464,210,1969
0.7835641129412465,1.753534262581889,1.322742820180127,1.388233986679566,2.884496729742283,-0.16316340352062567,2.6306479323828786,1.3359030458402381,0.006136821954560253,0.28273700304120136,1.5423267379676606,-0.5361629998579605,1.7291009524876284,-0.3023663071850197
3,329
Monovalent inorganic cation homeostasis
12
28
2.788323
0.005298
Q9NWW5,Q9Y487,Q9Y5X3,O75503,P50897,Q93050,Q8N511,P05023,P0CG08,Q9HC07,P51790,P55011
Processes and pathways
GO Biological process
msigdb_gobp
97,226,387,200,16,209,306,213,271,126,379,441
200,1187,3047,213,830,903,271,2873,1513,16,1077,379,910,441,2540,1061,306,539,209,767,2745,126,97,1462,2083,226,387,2865
1.753534262581889,0.08891345160359984,-0.935522252488236,1.7045591482602571,0.37719373688093016,0.298590741936191,1.4271606806581227,-0.7609097368252487,-0.11183646061143145,3.377464146466878,0.154267746052456,1.066584662292758,0.298590741936191,0.9268712703037668,-0.5730062666389593,0.1704881613421552,1.322742820180127,0.7690287674741151,1.7291009524876284,0.454709104760018,-0.6661782994152631,2.1983218430127764,2.3753585548204437,-0.07787664700247479,-0.35546637806239667,1.642723772750052,1.066584662292758,-0.741836257964152
3,329
Protein transport
77
272
2.781726
0.005407
Q9NS69,O43731,Q9HCU5,Q99595,O96008,Q8N4H5,Q9P2W9,Q7Z3B4,P61619,O95721,P24390,Q9Y5U9,Q15629,Q13505,Q9HD26,Q8N5M9,P52292,Q9UEU0,O14925,Q12907,Q9Y3A6,Q9BUN8,O15127,A6NIH7,Q9UMY4,O75431,Q9HD20,Q3ZCQ8,Q8N612,P61026,Q7Z3C6,O43823,Q92783,Q99442,O00471,O95070,O43752,Q9UGP8,Q92973,Q15907,O15397,O75381,Q96L92,O60831,Q8TEX9,Q9Y5J7,Q9BTX1,Q969Q5,Q9Y3B3,O60220,P41208,Q8NFH5,P0CG08,Q8N4Q1,Q9H4A6,Q03518,P49257,P51572,Q9Y5J9,Q9Y3E0,Q96JB2,P52294,Q15388,Q9Y5X3,O43615,A0AVF1,O15504,O75694,Q8N1F7,P49755,P57740,Q15363,Q86Y82,Q9HAV4,Q9UPT5,O95219,Q6NUQ1
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,1,516,4,510,7,10,530,11,522,19,541,32,52,573,58,580,583,68,584,591,81,86,88,613,614,105,620,622,630,644,639,654,657,648,146,167,176,177,194,198,199,217,227,228,229,235,249,261,259,263,277,271,290,317,324,327,345,361,366,369,375,381,387,390,388,393,395,398,435,463,464,465,468,475,471,492
388,2524,1877,88,2643,1970,1185,3059,1129,648,1289,957,775,2949,799,68,3045,2844,649,86,198,719,393,1759,390,1549,839,1,2364,167,639,259,2328,1840,1466,1102,800,1203,2559,721,227,2212,199,735,614,2089,395,2134,1379,2848,2446,146,471,1469,801,1662,522,3169,510,271,1135,1511,2099,2100,1261,1730,19,1296,1164,2566,1044,263,2143,1805,2412,327,1558,435,2144,1850,1298,1021,1077,1227,2261,345,863,580,375,1477,3014,2192,1247,2414,1851,1414,463,2263,2146,3248,693,982,630,1480,11,1442,2147,819,1416,2936,1774,1948,1301,324,914,1303,1900,2227,966,584,3174,52,1775,1081,706,1815,844,1328,464,381,2154,32,3200,194,620,3312,1738,1420,916,1739,1271,1953,492,1993,530,644,465,3300,1250,1233,1956,398,1251,7,290,58,622,1394,882,2121,1530,3231,684,277,715,1866,228,1911,1195,2276,2237,1066,1603,654,1912,177,249,1745,767,2743,2863,1235,369,1308,217,2510,1824,1870,1825,657,1609,825,4,2745,1610,1871,2594,235,81,787,3220,1010,2004,1494,3324,867,2513,837,2005,1498,2810,317,2515,2707,1791,1747,3270,468,516,105,573,1422,2169,2516,926,1691,731,1092,1750,0,2438,1093,1458,790,1922,1716,995,1923,10,2640,1798,2172,583,176,1035,3023,2678,3223,1581,1221,2812,613,2600,827,475,2248,2714,1659,591,261,2715,366,1836,3075,229,361,1801,541,2399,387,3010,2323
1.0527700672687526,-0.5730062666389593,-0.2847767900895569,2.4295325225007747,-0.628725162512366,-0.3200108532156369,0.08891345160359984,-0.9552596524756897,0.12168565981800496,0.5915874267986064,0.006136821954560253,0.2508944256563078,0.4392916383060073,-0.8185184586058571,0.40832875583933903,2.6202449005730086,-0.935522252488236,-0.741836257964152,0.5915874267986064,2.451053270581627,1.753534262581889,0.4854172249404048,1.0389210906111273,-0.2323351001172288,1.0527700672687526,-0.1288935074639876,0.36156109284692456,4.2619285086064,-0.49955830659898626,1.9216061509487739,0.6065913728144292,1.4914371362101484,-0.4813444898962475,-0.2672419692131069,-0.09483094105616925,0.13800033403990275,0.40832875583933903,0.07245537536615151,-0.591518313499491,0.4854172249404048,1.6302733030807859,-0.42705275376542584,1.753534262581889,0.4700842251171112,0.636478968201094,-0.37327803753599764,1.0389210906111273,-0.3911460873340927,-0.0441205412804845,-0.741836257964152,-0.5361629998579605,2.0270100122467594,0.869989669830986,-0.09483094105616925,0.40832875583933903,-0.18037686968631964,0.7835641129412465,-1.1360526844862961,0.7980616903860556,1.4271606806581227,0.12168565981800496,-0.11183646061143145,-0.37327803753599764,-0.37327803753599764,0.022789956142157834,-0.2149624012246617,3.3136457769691683,0.006136821954560253,0.10532345566594865,-0.591518313499491,0.18666184318592197,1.4658159453703792,-0.3911460873340927,-0.24976151481950415,-0.5178310194419322,1.243119425650111,-0.1288935074639876,0.941001406390935,-0.3911460873340927,-0.2672419692131069,0.006136821954560253,0.20278905267534755,0.154267746052456,0.055948952378408766,-0.44509207637698556,1.1893957791189034,0.3458847108749264,0.6957787564513349,1.0803650412592236,-0.09483094105616925,-0.896252211455973,-0.40907087562127437,0.039393905728626555,-0.5178310194419322,-0.2672419692131069,-0.06097327927337434,0.8842645870828738,-0.44509207637698556,-0.3911460873340927,-1.4077812643017102,0.5311657302429517,0.23490508817494482,0.6215551504261415,-0.09483094105616925,3.60814852819791,-0.07787664700247479,-0.3911460873340927,0.3927828796273702,-0.06097327927337434,-0.7992504105201905,-0.2323351001172288,-0.3023663071850197,0.006136821954560253,1.256469540383378,0.298590741936191,0.006136821954560253,-0.2847767900895569,-0.42705275376542584,0.2508944256563078,0.6810127242035948,-1.1360526844862961,2.904304439560962,-0.2323351001172288,0.154267746052456,0.5159577563542814,-0.24976151481950415,0.36156109284692456,-0.010565780915623473,0.8842645870828738,1.066584662292758,-0.3911460873340927,3.211822037822721,-1.1976178933685362,1.777860007244974,0.636478968201094,-2.7260153317748412,-0.2149624012246617,-0.06097327927337434,0.298590741936191,-0.2149624012246617,0.022789956142157834,-0.3023663071850197,0.8413297109269698,-0.3200108532156369,0.7835641129412465,0.6065913728144292,0.8842645870828738,-2.017198142965321,0.039393905728626555,0.055948952378408766,-0.3023663071850197,1.0389210906111273,0.039393905728626555,3.8294183006436957,1.3751974618052982,2.7944625478406078,0.636478968201094,-0.0441205412804845,0.3301643523967748,-0.37327803753599764,-0.11183646061143145,-1.3227831445496594,0.5463324682304516,1.4271606806581227,0.5007083280125337,-0.2672419692131069,1.6302733030807859,-0.2847767900895569,0.08891345160359984,-0.44509207637698556,-0.42705275376542584,0.1704881613421552,-0.1460023860587023,0.5915874267986064,-0.2847767900895569,1.8741054980652416,1.554976405224503,-0.2149624012246617,0.454709104760018,-0.6661782994152631,-0.741836257964152,0.055948952378408766,1.107823807425468,0.006136821954560253,1.7045591482602571,-0.554554622770862,-0.24976151481950415,-0.2672419692131069,-0.24976151481950415,0.5915874267986064,-0.1460023860587023,0.3927828796273702,3.944919490586592,-0.6661782994152631,-0.1460023860587023,-0.2672419692131069,-0.591518313499491,1.5927529048138849,2.504488675343527,0.4392916383060073,-1.2598565555717247,0.2188700487407775,-0.3200108532156369,-0.09483094105616925,-7.5492546418837945,0.3458847108749264,-0.554554622770862,0.37719373688093016,-0.3200108532156369,-0.09483094105616925,-0.7038809140344804,1.2963283762981763,-0.554554622770862,-0.6474207470427343,-0.2323351001172288,-0.2149624012246617,-1.559646337973014,0.8842645870828738,0.7980616903860556,2.342595734045094,0.7105058479496481,-0.06097327927337434,-0.3911460873340927,-0.554554622770862,0.298590741936191,-0.18037686968631964,0.4854172249404048,0.154267746052456,-0.2149624012246617,4.436105046391561,-0.5178310194419322,0.154267746052456,-0.07787664700247479,0.4392916383060073,-0.2847767900895569,-0.1976430971357671,0.23490508817494482,-0.2847767900895569,3.634145715730923,-0.6100911490136454,-0.2323351001172288,-0.3911460873340927,0.6957787564513349,1.8860190523984428,0.20278905267534755,-0.896252211455973,-0.628725162512366,-1.2807549209207683,-0.1288935074639876,0.07245537536615151,-0.7038809140344804,0.6513630331017662,-0.591518313499491,0.3927828796273702,0.869989669830986,-0.42705275376542584,-0.6474207470427343,-0.16316340352062567,0.6810127242035948,1.4914371362101484,-0.6474207470427343,1.1215025199124145,-0.24976151481950415,-0.9552596524756897,1.6302733030807859,1.148759408279367,-0.2323351001172288,0.7690287674741151,-0.49955830659898626,1.066584662292758,-0.8767186560343143,-0.46318920134873065
3,329
Glycoprotein metabolic process
31
63
2.774704
0.005525
P15291,Q92542,Q14165,Q9Y673,O43909,O43505,Q9BXS4,P46977,P26572,O00754,Q9BT22,P04844,Q8TCJ2,P62820,Q9H4A6,Q8NCH0,Q9H0U4,O60476,O14734,Q9H9S5,Q7LGA3,Q6ZXV5,O60568,Q86YN1,Q10472,Q9NX62,Q99805,Q96JB2,P04843,O15118,Q9HC07
Processes and pathways
GO Biological process
msigdb_gobp
756,256,761,791,401,408,153,283,546,295,300,557,563,819,317,61,837,65,838,601,211,340,720,103,231,360,634,369,626,253,126
2985,295,838,253,2289,408,401,65,1038,720,2485,1103,840,1342,626,557,2096,756,546,1886,930,981,283,3290,819,1948,1562,1023,914,984,231,2798,761,1990,986,340,211,1174,2034,103,61,563,256,369,2509,3055,2745,634,1336,300,153,1236,837,1313,317,601,126,360,2477,2518,1462,1318,791
-0.8572521419813814,1.3490321328683648,0.36156109284692456,1.5169403833744672,-0.46318920134873065,1.0111193241132475,1.02503756555061,2.6410312412580748,0.18666184318592197,0.4854172249404048,-0.554554622770862,0.13800033403990275,0.36156109284692456,-0.02731813899443857,0.6215551504261415,0.725194197877662,-0.37327803753599764,0.454709104760018,0.7544554622052062,-0.2847767900895569,0.28273700304120136,0.23490508817494482,1.4142154574761407,-1.7838503924546287,0.3927828796273702,-0.3023663071850197,-0.1288935074639876,0.20278905267534755,0.298590741936191,0.23490508817494482,1.6177947509504282,-0.7038809140344804,0.454709104760018,-0.3200108532156369,0.23490508817494482,1.2028754731019637,1.7168436706493653,0.10532345566594865,-0.3377107639133768,2.342595734045094,2.7336053345192104,0.725194197877662,1.5169403833744672,1.107823807425468,-0.554554622770862,-0.935522252488236,-0.6661782994152631,0.6215551504261415,-0.010565780915623473,1.3359030458402381,1.9920988307239456,0.055948952378408766,0.37719373688093016,0.006136821954560253,1.2963283762981763,0.6662075505020892,2.1983218430127764,1.148759408279367,-0.5361629998579605,-0.554554622770862,-0.07787664700247479,0.006136821954560253,0.4392916383060073
3,329
Hypertrophic cardiomyopathy
36
119
2.773887
0.005539
Q9NPL8,Q96CU9,Q9NX14,Q9Y6M9,P47985,Q8WXH0,P15586,O43676,P09493,P10253,P00846,O15360,P16278,P06280,Q00325,Q7KZN9,Q9Y4P3,Q13423,Q53H12,Q86Y39,P50402,P53701,Q5XKP0,Q9H061,O43819,Q8IUX1,Q9NVI7,Q9P0J0,Q9BXW9,P03915,P50416,Q99797,P54802,P12235,P00403,O60313
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
135,139,533,270,526,405,536,28,544,545,159,171,298,301,559,47,315,567,568,62,318,73,79,87,470,92,352,225,484,503,246,115,248,244,243,124
1259,1507,1288,171,28,1931,470,124,1975,777,689,977,578,1469,1551,978,1244,243,159,902,841,503,301,2561,1664,1842,544,1436,545,244,1411,536,298,859,2492,2820,873,3161,3258,1439,795,2221,2222,2188,1804,2333,2411,526,2299,3000,318,246,1110,73,248,1479,1079,3050,3184,2976,1897,1948,559,2194,2903,567,2306,2963,2424,1210,1305,1083,1419,568,1525,2696,79,47,62,92,822,2429,3005,1451,2507,405,655,767,139,866,3069,115,2774,748,1216,1965,484,2317,87,2747,2980,2078,2595,3058,135,2921,352,533,732,994,225,1654,3189,1969,2813,1223,315,3309,270
0.022789956142157834,-0.11183646061143145,0.006136821954560253,1.897906941241736,3.249069666218409,-0.3023663071850197,0.869989669830986,2.209555246837717,-0.3200108532156369,0.4392916383060073,0.5311657302429517,0.23490508817494482,0.6957787564513349,-0.09483094105616925,-0.1288935074639876,0.23490508817494482,0.039393905728626555,1.554976405224503,1.9452039775495766,0.298590741936191,0.36156109284692456,0.8125216901520601,1.322742820180127,-0.591518313499491,-0.18037686968631964,-0.2672419692131069,0.7544554622052062,-0.07787664700247479,0.7544554622052062,1.554976405224503,-0.06097327927337434,0.7690287674741151,1.3359030458402381,0.3458847108749264,-0.554554622770862,-0.72282678915474,0.3301643523967748,-1.115678167758971,-1.4723719627180456,-0.07787664700247479,0.4238315983927201,-0.42705275376542584,-0.42705275376542584,-0.40907087562127437,-0.24976151481950415,-0.4813444898962475,-0.5178310194419322,0.7835641129412465,-0.46318920134873065,-0.8767186560343143,1.2830738672582187,1.554976405224503,0.13800033403990275,2.5679313292978785,1.554976405224503,-0.09483094105616925,0.154267746052456,-0.935522252488236,-1.1565004674234014,-0.8378522233550003,-0.2847767900895569,-0.3023663071850197,0.725194197877662,-0.40907087562127437,-0.7800476461635257,0.7105058479496481,-0.46318920134873065,-0.8185184586058571,-0.5178310194419322,0.07245537536615151,0.006136821954560253,0.154267746052456,-0.06097327927337434,0.7105058479496481,-0.11183646061143145,-0.6474207470427343,2.525717907582542,3.0119806996316236,2.6926544679277815,2.418740417134722,0.3927828796273702,-0.5178310194419322,-0.8767186560343143,-0.07787664700247479,-0.554554622770862,1.02503756555061,0.5915874267986064,0.454709104760018,2.1076193115504527,0.3458847108749264,-0.9552596524756897,2.254260805481034,-0.6849982202518423,0.4700842251171112,0.07245537536615151,-0.3023663071850197,0.8556781055702337,-0.46318920134873065,2.440303446756386,-0.6661782994152631,-0.8378522233550003,-0.35546637806239667,-0.591518313499491,-0.935522252488236,2.119039208483976,-0.7800476461635257,1.175883307390258,0.7835641129412465,0.4854172249404048,0.23490508817494482,1.642723772750052,-0.16316340352062567,-1.1565004674234014,-0.3023663071850197,-0.7038809140344804,0.07245537536615151,1.3095513119692044,-2.4114915018898193,1.4400757456470827
3,329
Endoplasmic reticulum to golgi vesicle mediated transport
34
66
2.764557
0.0057
Q9HCU5,O43731,Q9Y3B3,Q9P2W9,Q9BVK6,O95070,P24390,O15027,Q9Y282,O14579,Q9Y5U9,Q6DD88,Q969X5,P49755,Q9HD26,P62820,P61019,Q9H0U4,Q8NHH9,P49257,Q12907,Q9BSR8,Q9Y3A6,Q15363,Q9NR31,O75340,Q9Y6Y8,P51572,Q96PC5,O15498,Q6NUQ1,O75396,Q96JB2,Q96RQ1
Processes and pathways
GO Biological process
msigdb_gobp
516,1,261,10,787,146,19,649,22,775,541,427,429,435,573,819,693,837,193,327,584,333,591,464,731,840,477,345,93,719,492,735,369,123
1546,775,649,719,1759,1,1203,840,735,2446,146,2969,1662,1511,19,1296,2412,327,435,345,863,3014,2192,2414,2456,693,819,914,584,1673,464,2154,916,427,492,2979,1743,193,2237,1066,988,429,369,93,123,333,787,837,516,573,2169,731,1126,10,2640,3271,2841,22,2206,591,261,2815,541,3010,2323,477
-0.1288935074639876,0.4392916383060073,0.5915874267986064,0.4854172249404048,-0.2323351001172288,4.2619285086064,0.07245537536615151,0.36156109284692456,0.4700842251171112,-0.5361629998579605,2.0270100122467594,-0.8378522233550003,-0.18037686968631964,-0.11183646061143145,3.3136457769691683,0.006136821954560253,-0.5178310194419322,1.243119425650111,0.941001406390935,1.1893957791189034,0.3458847108749264,-0.896252211455973,-0.40907087562127437,-0.5178310194419322,-0.5361629998579605,0.5311657302429517,0.3927828796273702,0.298590741936191,0.6810127242035948,-0.18037686968631964,0.8842645870828738,-0.3911460873340927,0.298590741936191,0.9691546034871085,0.8413297109269698,-0.8378522233550003,-0.2149624012246617,1.7899828295376359,-0.42705275376542584,0.1704881613421552,0.23490508817494482,0.9691546034871085,1.107823807425468,2.418740417134722,2.2207657546992476,1.229737143732253,0.4392916383060073,0.37719373688093016,0.7980616903860556,0.7105058479496481,-0.3911460873340927,0.4854172249404048,0.13800033403990275,3.634145715730923,-0.6100911490136454,-1.559646337973014,-0.72282678915474,3.304467416705692,-0.40907087562127437,0.6810127242035948,1.4914371362101484,-0.7038809140344804,0.7690287674741151,-0.8767186560343143,-0.46318920134873065,0.869989669830986
3,329
Alzheimers disease
17
66
2.762789
0.005731
Q92542,O95168,O95139,P00403,P78536,O14548,Q9UDW1,P14406,P16615,Q9Y6M9,P24539,P47985,P13073,O75438,O14949,O43676,P00846
Processes and pathways
KEGG Pathways
msigdb_kegg
256,449,224,243,350,416,8,44,173,270,111,526,184,242,26,28,159
1507,1288,416,26,28,1975,777,689,242,977,997,224,449,1661,1551,1244,243,159,2018,903,1343,1133,793,523,1190,184,44,2138,904,1293,173,2052,2820,628,873,757,111,2872,2873,3161,1513,1439,2023,875,1768,526,2790,931,3000,1890,1022,1079,350,1811,2623,3093,1269,2736,1232,1305,256,2745,3069,8,1462,270
-0.11183646061143145,0.006136821954560253,0.9831780141194827,3.2583418811704092,3.249069666218409,-0.3200108532156369,0.4392916383060073,0.5311657302429517,1.554976405224503,0.23490508817494482,0.2188700487407775,1.642723772750052,0.9127052073021598,-0.18037686968631964,-0.1288935074639876,0.039393905728626555,1.554976405224503,1.9452039775495766,-0.3377107639133768,0.298590741936191,-0.02731813899443857,0.12168565981800496,0.4238315983927201,0.7835641129412465,0.08891345160359984,1.8382097591474658,3.0313319722377035,-0.3911460873340927,0.298590741936191,0.006136821954560253,1.8860190523984428,-0.35546637806239667,-0.72282678915474,0.6215551504261415,0.3301643523967748,0.454709104760018,2.287553021209273,-0.7609097368252487,-0.7609097368252487,-1.115678167758971,-0.11183646061143145,-0.07787664700247479,-0.3377107639133768,0.3301643523967748,-0.2323351001172288,0.7835641129412465,-0.7038809140344804,0.28273700304120136,-0.8767186560343143,-0.2847767900895569,0.20278905267534755,0.154267746052456,1.175883307390258,-0.24976151481950415,-0.6100911490136454,-0.9949415319801789,0.022789956142157834,-0.6661782994152631,0.055948952378408766,0.006136821954560253,1.5169403833744672,-0.6661782994152631,-0.9552596524756897,3.6857689979534722,-0.07787664700247479,1.4400757456470827
3,329
Phospholipid metabolism
8
12
2.759342
0.005792
P35790,Q9UG56,Q96N66,P48651,Q9HCL2,Q9NPH0,Q92604,O95674
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
353,100,265,330,364,140,278,181
1430,181,353,330,494,278,700,265,364,140,1541,100
-0.07787664700247479,1.8502009604159466,1.162337902585846,1.229737143732253,0.8413297109269698,1.4271606806581227,0.5311657302429517,1.4658159453703792,1.1351476669380705,2.1076193115504527,-0.11183646061143145,2.3535384052387704
3,329
Abnormal visual electrophysiology
13
52
2.757401
0.005826
O60220,O95140,O75503,Q96S66,O43924,Q9NZJ7,P50897,P07602,P12235,O14773,O60313,Q15067,P00846
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
259,357,200,202,107,210,16,54,244,186,124,284,159
186,3159,2362,521,2647,107,259,124,200,2486,2134,2403,357,159,54,244,2101,2566,1044,1804,1892,16,932,1479,3032,833,566,2798,1637,284,358,1419,568,2071,1004,2805,1176,678,1573,3110,1396,202,2004,1337,2513,1540,708,926,1578,1092,210,1238
1.8261924564729928,-1.115678167758971,-0.49955830659898626,0.7835641129412465,-0.628725162512366,2.3206447765853273,1.4914371362101484,2.209555246837717,1.753534262581889,-0.554554622770862,-0.3911460873340927,-0.5178310194419322,1.148759408279367,1.9452039775495766,2.884496729742283,1.554976405224503,-0.37327803753599764,-0.591518313499491,0.18666184318592197,-0.24976151481950415,-0.2847767900895569,3.377464146466878,0.28273700304120136,-0.09483094105616925,-0.9158532586395145,0.37719373688093016,0.7105058479496481,-0.7038809140344804,-0.16316340352062567,1.4012399388701977,1.148759408279367,-0.06097327927337434,0.7105058479496481,-0.35546637806239667,0.2188700487407775,-0.7038809140344804,0.10532345566594865,0.561458187161226,-0.1288935074639876,-1.0148869538509337,-0.0441205412804845,1.753534262581889,-0.3200108532156369,-0.010565780915623473,-0.554554622770862,-0.11183646061143145,0.5159577563542814,0.298590741936191,-0.1288935074639876,0.154267746052456,1.7291009524876284,0.055948952378408766
3,329
Bulbar signs
7
12
2.757113
0.005831
P35637,Q99720,Q9NZJ7,P07602,P03915,P04062,P00846
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
420,67,210,54,503,89,159
521,159,503,89,1042,54,420,1138,988,67,210,1403
0.7835641129412465,1.9452039775495766,0.8125216901520601,2.4295325225007747,0.18666184318592197,2.884496729742283,0.9831780141194827,0.12168565981800496,0.23490508817494482,2.6306479323828786,1.7291009524876284,-0.0441205412804845
3,329
RNA recognition motif domain [IPR000504]
59
120
4.45559
0.000008
O43347,Q01085,P23588,P98175,Q13148,Q96PK6,Q07955,Q76FK4,P31943,Q13247,Q13242,Q9GZT3,Q14103,Q8TBF4,A0AV96,P09651,Q01844,O14979,Q9UN86,Q86V81,Q9BWF3,Q8IXT5,P33240,O43719,P08621,P51991,Q99729,P31942,Q15717,Q93062,Q16629,P52597,Q8N684,Q13283,P38159,P22626,P23246,Q13595,Q92804,Q8IY67,Q15056,P62995,O60506,P43243,P55795,Q01081,P52756,O43390,Q13243,Q15427,P26368,P35637,P98179,Q15287,Q9Y5S9,Q96T37,Q9UHX1,Q14011,P18615
Sequence
InterPro Domain
interpro_domain
127,387,384,136,525,411,405,540,148,275,406,545,538,420,414,415,171,172,438,175,435,560,677,551,552,449,454,188,589,190,590,313,453,451,194,198,701,709,74,333,332,328,322,704,218,345,217,340,374,613,99,107,111,357,514,633,378,124,625
414,1397,172,1130,127,340,551,322,2906,909,951,1815,834,2739,552,1071,415,1506,1189,625,2026,198,701,384,99,1453,1571,188,148,677,107,194,1001,704,2390,449,1082,313,217,218,1085,328,2679,136,111,345,387,1885,171,1938,405,1520,1582,525,1829,406,374,275,451,1306,709,124,538,843,964,2504,883,332,1006,357,1657,613,589,590,1098,2918,1100,540,1213,175,560,333,2048,453,1364,420,1792,852,1535,1598,74,2124,190,2127,750,411,633,2238,454,1849,435,2007,2008,545,856,2192,3151,1679,1327,2015,2658,378,1389,1739,438,2814,1124,2422,514,947
0.7711752687730454,0.02041518328356238,1.3780765416953078,0.1448904124117295,1.7344565433373995,0.8971742688101305,0.5700786462448547,0.9224024553533663,-0.7204036003306101,0.2696342378209103,0.24466428827712608,-0.15338637233363414,0.3196055701226996,-0.5976903988876788,0.5700786462448547,0.1698178934496409,0.7711752687730454,-0.029298246881930074,0.11997367421113542,0.4948303001812229,-0.25245210761188314,1.2765641279126316,0.4196726296872428,0.821546325140021,2.06683835096759,-0.00444706101777177,-0.05413831981279846,1.3273027404887678,1.5815183607346968,0.44471503673584983,1.9900137899010935,1.3019290187854229,0.21970488141706138,0.4196726296872428,-0.4007005636256563,0.7208426436394583,0.1698178934496409,0.9476400134093361,1.2005227817735866,1.2005227817735866,0.1698178934496409,0.9224024553533663,-0.5485168178411735,1.6579497333950177,1.887693249412294,0.8971742688101305,0.821546325140021,-0.17817004308089993,1.4034765545203647,-0.20294226174328334,0.7963560132112784,-0.029298246881930074,-0.05413831981279846,0.6202939974103107,-0.15338637233363414,0.7963560132112784,0.8467461646808371,1.0486832017281793,0.7208426436394583,0.07017263198353871,0.4196726296872428,1.7599754364752334,0.5951813720548296,0.3196055701226996,0.24466428827712608,-0.4500213613594855,0.2946146812215758,0.9224024553533663,0.21970488141706138,0.8719554923012351,-0.07896722474974421,0.5199030665002794,0.5449858631910435,0.5449858631910435,0.1698178934496409,-0.7204036003306101,0.1698178934496409,0.5951813720548296,0.11997367421113542,1.3780765416953078,0.5700786462448547,0.9224024553533663,-0.25245210761188314,0.7208426436394583,0.04528843208172267,0.7711752687730454,-0.1285913075228445,0.3196055701226996,-0.029298246881930074,-0.05413831981279846,2.42628438755721,-0.2771896156285405,1.3273027404887678,-0.2771896156285405,0.39464043317762726,0.7963560132112784,0.4948303001812229,-0.326629498975423,0.7208426436394583,-0.15338637233363414,0.7460041320543394,-0.22770296967824383,-0.22770296967824383,0.5951813720548296,0.3196055701226996,-0.3019154331601609,-1.0865677781367193,-0.07896722474974421,0.07017263198353871,-0.22770296967824383,-0.5239113880300665,0.8467461646808371,0.04528843208172267,-0.10378490605866271,0.7460041320543394,-0.6222584106680328,0.1698178934496409,-0.4007005636256563,0.6454164794914127,0.2696342378209103
3,328
RNA-binding domain superfamily [IPR035979]
55
134
4.126711
0.000037
O43347,Q01085,P23588,P98175,Q13148,Q96PK6,Q07955,Q76FK4,P31943,Q13247,Q13242,Q9GZT3,Q14103,Q8TBF4,Q7Z569,A0AV96,P09651,Q01844,O14979,Q9UN86,Q86V81,Q9BWF3,Q8IXT5,O43719,P08621,P51991,Q99729,P31942,Q15717,Q93062,Q16629,P52597,Q8N684,Q13283,P38159,P22626,Q8IY67,Q92804,Q15056,P62995,O60506,P55795,Q01081,P52756,O43390,Q13243,Q15427,P26368,P35637,P98179,Q15287,Q9Y5S9,Q96T37,Q9UHX1,Q14011
Sequence
InterPro Superfamily
interpro_homologous_superfamily
127,387,384,136,525,411,405,540,148,275,406,545,538,420,418,414,415,171,172,438,175,435,560,551,552,449,454,188,589,190,590,313,453,451,194,198,333,74,332,328,322,218,345,217,340,374,613,99,107,111,357,514,633,378,124
414,1397,172,1130,127,340,551,322,2906,909,2737,951,765,1815,834,2739,552,1071,415,1506,1189,625,2026,198,701,384,99,1453,1571,188,148,677,107,194,1001,704,2390,449,1082,313,217,218,1085,328,2679,136,111,345,387,1885,171,1938,405,1520,1582,525,1829,406,374,275,451,1306,709,124,538,843,964,2504,883,332,1006,357,1657,613,589,590,1098,2918,1100,1532,540,418,1213,175,560,333,2048,453,1364,3287,420,1792,852,1535,1598,2123,74,2124,190,2127,750,411,633,2238,454,1479,1849,435,1058,2007,2008,2997,545,1485,856,2192,3151,1679,1327,2015,2658,2468,378,1389,1739,2071,3189,438,2814,2840,1124,2422,514,947
0.7711752687730454,0.02041518328356238,1.3780765416953078,0.1448904124117295,1.7344565433373995,0.8971742688101305,0.5700786462448547,0.9224024553533663,-0.7204036003306101,0.2696342378209103,-0.5976903988876788,0.24466428827712608,0.36961849331166047,-0.15338637233363414,0.3196055701226996,-0.5976903988876788,0.5700786462448547,0.1698178934496409,0.7711752687730454,-0.029298246881930074,0.11997367421113542,0.4948303001812229,-0.25245210761188314,1.2765641279126316,0.4196726296872428,0.821546325140021,2.06683835096759,-0.00444706101777177,-0.05413831981279846,1.3273027404887678,1.5815183607346968,0.44471503673584983,1.9900137899010935,1.3019290187854229,0.21970488141706138,0.4196726296872428,-0.4007005636256563,0.7208426436394583,0.1698178934496409,0.9476400134093361,1.2005227817735866,1.2005227817735866,0.1698178934496409,0.9224024553533663,-0.5485168178411735,1.6579497333950177,1.887693249412294,0.8971742688101305,0.821546325140021,-0.17817004308089993,1.4034765545203647,-0.20294226174328334,0.7963560132112784,-0.029298246881930074,-0.05413831981279846,0.6202939974103107,-0.15338637233363414,0.7963560132112784,0.8467461646808371,1.0486832017281793,0.7208426436394583,0.07017263198353871,0.4196726296872428,1.7599754364752334,0.5951813720548296,0.3196055701226996,0.24466428827712608,-0.4500213613594855,0.2946146812215758,0.9224024553533663,0.21970488141706138,0.8719554923012351,-0.07896722474974421,0.5199030665002794,0.5449858631910435,0.5449858631910435,0.1698178934496409,-0.7204036003306101,0.1698178934496409,-0.029298246881930074,0.5951813720548296,0.7711752687730454,0.11997367421113542,1.3780765416953078,0.5700786462448547,0.9224024553533663,-0.25245210761188314,0.7208426436394583,0.04528843208172267,-2.211557361847043,0.7711752687730454,-0.1285913075228445,0.3196055701226996,-0.029298246881930074,-0.05413831981279846,-0.2771896156285405,2.42628438755721,-0.2771896156285405,1.3273027404887678,-0.2771896156285405,0.39464043317762726,0.7963560132112784,0.4948303001812229,-0.326629498975423,0.7208426436394583,-0.00444706101777177,-0.15338637233363414,0.7460041320543394,0.19475606654496544,-0.22770296967824383,-0.22770296967824383,-0.7938772325700006,0.5951813720548296,-0.00444706101777177,0.3196055701226996,-0.3019154331601609,-1.0865677781367193,-0.07896722474974421,0.07017263198353871,-0.22770296967824383,-0.5239113880300665,-0.42536699660255867,0.8467461646808371,0.04528843208172267,-0.10378490605866271,-0.25245210761188314,-1.2321586172414605,0.7460041320543394,-0.6222584106680328,-0.6468138089434564,0.1698178934496409,-0.4007005636256563,0.6454164794914127,0.2696342378209103
3,328
Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]
61
132
4.08109
0.000045
O43347,Q01085,P23588,P98175,Q13148,Q96PK6,Q07955,Q76FK4,P31943,Q13247,Q13242,Q9GZT3,Q14103,Q8TBF4,A0AV96,Q9H501,P09651,Q01844,O14979,Q9UN86,Q86V81,Q9BWF3,Q8IXT5,P33240,O43719,P08621,P51991,Q99729,P31942,Q15717,Q93062,Q16629,P52597,Q8N684,Q13283,P38159,Q16540,P22626,P23246,Q13595,Q92804,Q8IY67,Q15056,P62995,O60506,P43243,P55795,Q01081,P52756,O43390,Q13243,Q15427,P26368,P35637,P98179,Q15287,Q9Y5S9,Q96T37,Q9UHX1,Q14011,P18615
Sequence
InterPro Superfamily
interpro_homologous_superfamily
127,387,384,136,525,411,405,540,148,275,406,545,538,420,414,567,415,171,172,438,175,435,560,677,551,552,449,454,188,589,190,590,313,453,451,194,712,198,701,709,74,333,332,328,322,704,218,345,217,340,374,613,99,107,111,357,514,633,378,124,625
414,1397,172,1130,127,340,551,322,2906,909,2737,951,765,1815,834,2739,552,1071,415,1506,1189,625,2026,198,701,384,99,1453,1571,188,148,677,107,194,1001,704,2390,449,1082,313,217,218,1085,2171,328,2679,136,111,345,387,1885,171,1938,405,1520,1582,525,1829,406,374,275,451,1306,709,124,538,843,964,2504,883,332,1006,357,1657,613,589,712,590,1098,2918,1100,540,1213,175,560,333,2048,453,1364,3287,420,1792,852,1535,1598,2123,74,2124,190,2127,750,411,633,2238,454,1849,435,2007,2008,2997,545,567,856,2192,3151,1679,1327,2015,2658,2468,378,1389,1739,2071,3189,438,2814,2840,1124,2422,514,947
0.7711752687730454,0.02041518328356238,1.3780765416953078,0.1448904124117295,1.7344565433373995,0.8971742688101305,0.5700786462448547,0.9224024553533663,-0.7204036003306101,0.2696342378209103,-0.5976903988876788,0.24466428827712608,0.36961849331166047,-0.15338637233363414,0.3196055701226996,-0.5976903988876788,0.5700786462448547,0.1698178934496409,0.7711752687730454,-0.029298246881930074,0.11997367421113542,0.4948303001812229,-0.25245210761188314,1.2765641279126316,0.4196726296872428,0.821546325140021,2.06683835096759,-0.00444706101777177,-0.05413831981279846,1.3273027404887678,1.5815183607346968,0.44471503673584983,1.9900137899010935,1.3019290187854229,0.21970488141706138,0.4196726296872428,-0.4007005636256563,0.7208426436394583,0.1698178934496409,0.9476400134093361,1.2005227817735866,1.2005227817735866,0.1698178934496409,-0.3019154331601609,0.9224024553533663,-0.5485168178411735,1.6579497333950177,1.887693249412294,0.8971742688101305,0.821546325140021,-0.17817004308089993,1.4034765545203647,-0.20294226174328334,0.7963560132112784,-0.029298246881930074,-0.05413831981279846,0.6202939974103107,-0.15338637233363414,0.7963560132112784,0.8467461646808371,1.0486832017281793,0.7208426436394583,0.07017263198353871,0.4196726296872428,1.7599754364752334,0.5951813720548296,0.3196055701226996,0.24466428827712608,-0.4500213613594855,0.2946146812215758,0.9224024553533663,0.21970488141706138,0.8719554923012351,-0.07896722474974421,0.5199030665002794,0.5449858631910435,0.4196726296872428,0.5449858631910435,0.1698178934496409,-0.7204036003306101,0.1698178934496409,0.5951813720548296,0.11997367421113542,1.3780765416953078,0.5700786462448547,0.9224024553533663,-0.25245210761188314,0.7208426436394583,0.04528843208172267,-2.211557361847043,0.7711752687730454,-0.1285913075228445,0.3196055701226996,-0.029298246881930074,-0.05413831981279846,-0.2771896156285405,2.42628438755721,-0.2771896156285405,1.3273027404887678,-0.2771896156285405,0.39464043317762726,0.7963560132112784,0.4948303001812229,-0.326629498975423,0.7208426436394583,-0.15338637233363414,0.7460041320543394,-0.22770296967824383,-0.22770296967824383,-0.7938772325700006,0.5951813720548296,0.5700786462448547,0.3196055701226996,-0.3019154331601609,-1.0865677781367193,-0.07896722474974421,0.07017263198353871,-0.22770296967824383,-0.5239113880300665,-0.42536699660255867,0.8467461646808371,0.04528843208172267,-0.10378490605866271,-0.25245210761188314,-1.2321586172414605,0.7460041320543394,-0.6222584106680328,-0.6468138089434564,0.1698178934496409,-0.4007005636256563,0.6454164794914127,0.2696342378209103
3,328
Mitotic g1 phase and g1 s transition
21
78
4.034986
0.000055
P28070,P56282,P25788,P00374,O75832,Q14181,P28072,P30154,P49721,Q9Y619,Q14566,O14818,P31350,Q9NR33,P30153,P49720,P04183,P20618,Q92530,Q99436,P60900
Processes and pathways
Reactome Pathways
msigdb_reactome
1,4,260,9,380,143,17,145,25,26,28,396,163,40,292,70,202,80,360,362,108
828,3121,1179,396,1500,1134,2820,380,9,202,2024,1401,2908,2578,836,2155,2087,2579,2205,426,80,1037,768,2207,260,1239,1981,2092,1,17,804,292,145,163,839,1765,2029,2030,999,2489,583,2543,2389,3113,1572,70,25,1641,1987,1084,4,108,772,1461,1646,1825,708,1648,1649,652,2500,1886,3025,1888,2553,143,28,1779,1593,360,362,1729,40,1733,3254,596,1175,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.1448904124117295,-0.6468138089434564,0.821546325140021,5.324012948167437,1.2512081018821377,-0.25245210761188314,0.02041518328356238,-0.7204036003306101,-0.49929362365311203,0.3196055701226996,-0.3019154331601609,-0.2771896156285405,-0.49929362365311203,-0.326629498975423,0.7460041320543394,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.22770296967824383,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.9981430916099898,1.6069870522177834,1.4543026398884171,0.3196055701226996,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,0.21970488141706138,-0.4500213613594855,0.5449858631910435,-0.47466359244301676,-0.4007005636256563,-0.9892231160423917,-0.05413831981279846,2.452016645869307,3.878282602092929,-0.07896722474974421,-0.22770296967824383,0.1698178934496409,6.439542763092297,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.4196726296872428,-0.07896722474974421,-0.07896722474974421,0.46976760864997624,-0.4500213613594855,-0.17817004308089993,-0.8427941071748147,-0.17817004308089993,-0.47466359244301676,1.6324641866784928,3.799957938157529,-0.1285913075228445,-0.05413831981279846,0.8719554923012351,0.8719554923012351,-0.10378490605866271,3.3832205189442597,-0.10378490605866271,-1.7135074577953051,0.5449858631910435,0.1448904124117295,3.85216794801156
3,328
Peptidase activity
29
116
3.947846
0.000079
P28070,Q13043,P07858,O95630,Q8TCT8,P53634,P42785,P28072,Q96FW1,P49721,P42574,P55786,Q9UIQ6,Q92542,Q9HB40,Q9HD42,Q9H3G5,P10619,P49720,P20618,O75976,Q9UJ14,Q99436,Q9NZ08,P60900,Q9NP73,Q5JRX3,Q9BXS4,O75844
Functions
GO Molecular function
msigdb_gomf
1,388,130,5,133,142,14,17,280,25,153,158,35,298,42,170,45,47,70,80,213,91,362,230,108,365,246,118,241
2841,1179,1031,831,2295,2079,241,213,2432,5,1035,1629,767,130,2254,47,2306,1631,1348,837,80,1761,1239,1,17,804,2311,2209,2259,1079,1818,153,1000,14,648,1193,2744,70,25,2165,1987,1145,3263,874,1355,142,3045,158,108,1579,386,3103,2791,1150,1305,1413,388,1153,2226,3009,1417,1257,3176,246,1590,1528,3029,2758,1318,1104,3202,2233,133,3242,298,3246,1111,2125,717,2859,1426,2861,1536,280,1267,1055,751,2833,2516,362,2601,2995,2726,2239,118,469,45,759,2837,595,42,2240,170,365,1114,510,1801,2902,230,35,91,3143,640,1970,1282,2017
-0.6713565219046082,0.11997367421113542,0.19475606654496544,0.3196055701226996,-0.37602212714831224,-0.2771896156285405,1.1245621542194768,1.2005227817735866,-0.42536699660255867,6.0400653546981165,0.19475606654496544,-0.07896722474974421,0.36961849331166047,1.7089459418696067,-0.3513317511686248,2.9164635722236136,-0.37602212714831224,-0.07896722474974421,0.04528843208172267,0.3196055701226996,2.323431235195337,-0.1285913075228445,0.09506773013462308,8.210394651537106,4.29697723951205,0.3446068566314095,-0.37602212714831224,-0.326629498975423,-0.3513317511686248,0.1698178934496409,-0.15338637233363414,1.5051632549185123,0.21970488141706138,4.323198569429893,0.46976760864997624,0.11997367421113542,-0.5976903988876788,2.452016645869307,3.878282602092929,-0.3019154331601609,-0.22770296967824383,0.1448904124117295,-1.9041971751685358,0.2946146812215758,0.04528843208172267,1.6324641866784928,-0.8672326458632422,1.479728647315875,1.9644215771503513,-0.05413831981279846,0.821546325140021,-0.964852260919415,-0.6222584106680328,0.1448904124117295,0.07017263198353871,0.02041518328356238,0.821546325140021,0.1448904124117295,-0.326629498975423,-0.8183422763589453,0.02041518328356238,0.09506773013462308,-1.1836861453389294,1.1245621542194768,-0.05413831981279846,-0.029298246881930074,-0.8427941071748147,-0.5976903988876788,0.07017263198353871,0.1698178934496409,-1.3289262534598685,-0.326629498975423,1.6834436618783488,-1.6177501613860807,0.9981430916099898,-1.6417145265685216,0.1698178934496409,-0.2771896156285405,0.4196726296872428,-0.6713565219046082,0.02041518328356238,-0.6713565219046082,-0.029298246881930074,1.0486832017281793,0.09506773013462308,0.19475606654496544,0.39464043317762726,-0.6468138089434564,-0.4500213613594855,0.8719554923012351,-0.49929362365311203,-0.7938772325700006,-0.5731098445670545,-0.326629498975423,1.8365815711642068,0.6956908444727835,3.0717987299654284,0.39464043317762726,-0.6468138089434564,0.5449858631910435,3.175495757798002,-0.326629498975423,1.428885264813286,0.8719554923012351,0.1698178934496409,0.6454164794914127,-0.1285913075228445,-0.6958864768820794,1.1751935571078382,3.46122934532905,2.195037402551606,-1.0622526018002627,0.4948303001812229,-0.20294226174328334,0.09506773013462308,-0.22770296967824383
3,328
Alternative mrna splicing via spliceosome
23
44
3.883679
0.000103
P98175,Q07955,Q13242,Q13247,P51116,O75525,P09651,Q92841,P51114,Q9BWF3,Q06787,Q15007,P38159,Q8IY67,P62995,Q96MU7,P52756,O60828,Q07666,Q15287,Q9Y5S9,P17844,Q9UHX1
Processes and pathways
GO Biological process
msigdb_gobp
136,405,406,275,271,157,415,169,293,435,429,182,194,333,328,205,217,341,482,357,514,370,378
1550,1287,341,157,521,415,1189,370,701,1453,1571,194,2390,293,271,918,1082,217,328,136,2107,1885,429,482,405,2223,1774,406,275,182,357,2406,333,1364,169,2124,750,205,633,435,378,1334,1226,514
-0.05413831981279846,0.07017263198353871,0.8971742688101305,1.479728647315875,0.6202939974103107,0.7711752687730454,0.11997367421113542,0.8467461646808371,0.4196726296872428,-0.00444706101777177,-0.05413831981279846,1.3019290187854229,-0.4007005636256563,0.9981430916099898,1.0486832017281793,0.2696342378209103,0.1698178934496409,1.2005227817735866,0.9224024553533663,1.6579497333950177,-0.2771896156285405,-0.17817004308089993,0.7460041320543394,0.6705487758636702,0.7963560132112784,-0.326629498975423,-0.1285913075228445,0.7963560132112784,1.0486832017281793,1.352685259282614,0.8719554923012351,-0.4007005636256563,0.9224024553533663,0.04528843208172267,1.428885264813286,-0.2771896156285405,0.39464043317762726,1.2512081018821377,0.4948303001812229,0.7460041320543394,0.8467461646808371,0.07017263198353871,0.11997367421113542,0.6454164794914127
3,328
Regulation of rna splicing
44
92
3.841567
0.000122
P98175,O75312,Q07955,P31943,Q13247,Q13242,P51116,O75525,P09651,Q07021,Q92841,Q9UMS4,P51114,Q9BWF3,Q8IXT5,Q06787,Q15007,P08621,P78362,P31942,Q8IYB3,P52597,Q16629,P38159,P22626,Q8IY67,P62995,Q96MU7,P55795,P52756,Q96PU8,O60828,Q15427,P26368,Q07666,P35637,P61978,P98179,Q15287,Q9Y5S9,P17844,Q13243,Q9UHX1,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
136,519,405,148,275,406,271,157,415,168,169,571,293,435,560,429,182,552,314,188,452,313,590,194,198,333,328,205,218,217,488,341,613,99,482,107,605,111,357,514,370,374,378,124
1550,341,519,2906,157,552,415,1402,1189,370,2623,2026,198,1349,99,1453,1982,1571,188,148,107,194,1641,2390,293,271,918,313,217,874,218,605,2265,2266,328,314,2679,136,111,2107,1885,429,168,482,405,1520,2270,1993,1582,1774,406,374,275,1465,709,124,1714,964,1206,182,357,613,1008,590,2406,2918,846,2757,2715,560,333,452,1364,852,169,2124,2127,205,488,2280,1056,633,1849,435,3156,856,3151,378,1389,571,1334,514
-0.05413831981279846,0.8971742688101305,0.6202939974103107,-0.7204036003306101,1.479728647315875,0.5700786462448547,0.7711752687730454,0.02041518328356238,0.11997367421113542,0.8467461646808371,-0.5239113880300665,-0.25245210761188314,1.2765641279126316,0.04528843208172267,2.06683835096759,-0.00444706101777177,-0.22770296967824383,-0.05413831981279846,1.3273027404887678,1.5815183607346968,1.9900137899010935,1.3019290187854229,-0.07896722474974421,-0.4007005636256563,0.9981430916099898,1.0486832017281793,0.2696342378209103,0.9476400134093361,1.2005227817735866,0.2946146812215758,1.2005227817735866,0.5199030665002794,-0.3513317511686248,-0.3513317511686248,0.9224024553533663,0.9476400134093361,-0.5485168178411735,1.6579497333950177,1.887693249412294,-0.2771896156285405,-0.17817004308089993,0.7460041320543394,1.428885264813286,0.6705487758636702,0.7963560132112784,-0.029298246881930074,-0.3513317511686248,-0.22770296967824383,-0.05413831981279846,-0.1285913075228445,0.7963560132112784,0.8467461646808371,1.0486832017281793,-0.00444706101777177,0.4196726296872428,1.7599754364752334,-0.10378490605866271,0.24466428827712608,0.11997367421113542,1.352685259282614,0.8719554923012351,0.5199030665002794,0.21970488141706138,0.5449858631910435,-0.4007005636256563,-0.7204036003306101,0.3196055701226996,-0.5976903988876788,-0.5731098445670545,0.5700786462448547,0.9224024553533663,0.7208426436394583,0.04528843208172267,0.3196055701226996,1.428885264813286,-0.2771896156285405,-0.2771896156285405,1.2512081018821377,0.6705487758636702,-0.3513317511686248,0.19475606654496544,0.4948303001812229,-0.15338637233363414,0.7460041320543394,-1.1108688125620438,0.3196055701226996,-1.0865677781367193,0.8467461646808371,0.04528843208172267,0.5700786462448547,0.07017263198353871,0.6454164794914127
3,328
Dna replication pre initiation
16
64
3.798663
0.000145
P28070,Q92530,P56282,Q99436,P49720,Q9NR33,P25788,O75832,P60900,Q14181,P20618,P28072,P49721,Q9Y619,Q14566,P52294
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,4,362,70,40,260,380,108,143,80,17,25,26,28,216
828,3121,1179,396,1500,1134,1229,2820,380,2908,2579,2580,2205,80,1037,768,2207,260,1239,1981,2092,1,17,804,1765,2029,2030,999,2489,2543,2389,3113,1572,70,25,1641,1987,216,1084,4,108,772,1461,1646,1825,2790,652,2500,1886,143,28,2713,2917,1779,1593,360,362,1729,40,1733,3254,596,1175,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.1448904124117295,0.09506773013462308,-0.6468138089434564,0.821546325140021,-0.7204036003306101,-0.49929362365311203,-0.49929362365311203,-0.326629498975423,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.22770296967824383,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,0.21970488141706138,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,-0.9892231160423917,-0.05413831981279846,2.452016645869307,3.878282602092929,-0.07896722474974421,-0.22770296967824383,1.2005227817735866,0.1698178934496409,6.439542763092297,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.6222584106680328,0.46976760864997624,-0.4500213613594855,-0.17817004308089993,1.6324641866784928,3.799957938157529,-0.5731098445670545,-0.7204036003306101,-0.1285913075228445,-0.05413831981279846,0.8719554923012351,0.8719554923012351,-0.10378490605866271,3.3832205189442597,-0.10378490605866271,-1.7135074577953051,0.5449858631910435,0.1448904124117295,3.85216794801156
3,328
Regulation of mrna splicing via spliceosome
34
68
3.695664
0.000219
P98175,Q13242,Q13247,P51116,O75525,P09651,Q07021,Q92841,Q9UMS4,P51114,Q9BWF3,Q06787,Q15007,P08621,P78362,Q8IYB3,Q16629,P38159,P22626,Q8IY67,P62995,Q96MU7,P52756,Q96PU8,P26368,Q07666,Q15427,P61978,Q15287,P98179,Q9Y5S9,P17844,Q9UHX1,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
136,406,275,271,157,415,168,169,571,293,435,429,182,552,314,452,590,194,198,333,328,205,217,488,99,482,613,605,357,111,514,370,378,124
1550,2906,157,552,415,1402,1189,370,2623,2026,198,99,1453,1982,1571,194,2390,293,271,918,217,874,605,328,314,2679,136,111,2107,1885,429,168,482,1520,2270,1774,406,275,1465,709,124,964,182,357,613,1008,590,2406,2918,2757,2715,333,452,1364,169,2124,2127,205,488,1056,633,1849,435,3156,378,571,1334,514
-0.05413831981279846,-0.7204036003306101,1.479728647315875,0.5700786462448547,0.7711752687730454,0.02041518328356238,0.11997367421113542,0.8467461646808371,-0.5239113880300665,-0.25245210761188314,1.2765641279126316,2.06683835096759,-0.00444706101777177,-0.22770296967824383,-0.05413831981279846,1.3019290187854229,-0.4007005636256563,0.9981430916099898,1.0486832017281793,0.2696342378209103,1.2005227817735866,0.2946146812215758,0.5199030665002794,0.9224024553533663,0.9476400134093361,-0.5485168178411735,1.6579497333950177,1.887693249412294,-0.2771896156285405,-0.17817004308089993,0.7460041320543394,1.428885264813286,0.6705487758636702,-0.029298246881930074,-0.3513317511686248,-0.1285913075228445,0.7963560132112784,1.0486832017281793,-0.00444706101777177,0.4196726296872428,1.7599754364752334,0.24466428827712608,1.352685259282614,0.8719554923012351,0.5199030665002794,0.21970488141706138,0.5449858631910435,-0.4007005636256563,-0.7204036003306101,-0.5976903988876788,-0.5731098445670545,0.9224024553533663,0.7208426436394583,0.04528843208172267,1.428885264813286,-0.2771896156285405,-0.2771896156285405,1.2512081018821377,0.6705487758636702,0.19475606654496544,0.4948303001812229,-0.15338637233363414,0.7460041320543394,-1.1108688125620438,0.8467461646808371,0.5700786462448547,0.07017263198353871,0.6454164794914127
3,328
Switching of origins to a post replicative state
16
58
3.667436
0.000245
P28070,Q92530,Q99436,P49720,P25788,O75832,Q16763,P60900,Q9UJX6,P20618,P28072,P49721,Q9Y619,Q14566,O14818,Q96DE5
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,41,108,212,80,17,25,26,28,396,161
828,3121,1179,396,1500,1134,380,2205,426,80,1037,768,2207,260,1239,2092,1,17,804,1817,1765,2029,2030,2489,2543,2389,70,25,1641,1987,1084,108,772,1461,1646,1825,1648,652,1886,3025,2553,28,2917,1779,41,360,161,362,1729,2361,3254,2070,906,724,212,596,1175,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.1448904124117295,0.821546325140021,-0.326629498975423,0.7460041320543394,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.15338637233363414,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.07896722474974421,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,3.799957938157529,-0.7204036003306101,-0.1285913075228445,3.253341222402017,0.8719554923012351,1.479728647315875,0.8719554923012351,-0.10378490605866271,-0.37602212714831224,-1.7135074577953051,-0.25245210761188314,0.2946146812215758,0.4196726296872428,1.225860974980719,0.5449858631910435,0.1448904124117295,3.85216794801156
3,328
Predicted secreted proteins
15
52
3.645789
0.000267
Q9UMX5,Q15165,P07858,O60568,Q8WUJ1,P11047,Q07021,Q9NZ08,Q9HB40,Q02818,P80303,P14174,Q08380,O75718,P10909
Functions
Protein Atlas Protein class
protein_atlas_protein_class
131,3,130,286,68,69,168,230,42,76,15,48,189,92,29
574,286,991,92,1560,1502,1345,1035,578,2084,1347,130,1445,674,29,69,48,1348,2027,676,1634,326,1513,3058,1248,1517,15,3103,1936,76,168,189,2551,2173,1307,3,659,3216,68,631,1164,785,1955,434,3248,759,1221,42,230,1122,131,3276
0.5449858631910435,1.0234085363357603,0.21970488141706138,2.169381905284358,-0.05413831981279846,-0.029298246881930074,0.04528843208172267,0.19475606654496544,0.5449858631910435,-0.2771896156285405,0.04528843208172267,1.7089459418696067,-0.00444706101777177,0.44471503673584983,3.721691432884529,2.452016645869307,2.9164635722236136,0.04528843208172267,-0.25245210761188314,0.44471503673584983,-0.07896722474974421,0.9224024553533663,-0.029298246881930074,-0.8916578122719323,0.09506773013462308,-0.029298246881930074,4.323198569429893,-0.964852260919415,-0.20294226174328334,2.3748425857753057,1.428885264813286,1.3273027404887678,-0.47466359244301676,-0.3019154331601609,0.07017263198353871,7.671600129643505,0.46976760864997624,-1.4013436347310846,2.477756443180388,0.4948303001812229,0.1448904124117295,0.36961849331166047,-0.20294226174328334,0.7460041320543394,-1.6417145265685216,0.39464043317762726,0.11997367421113542,3.175495757798002,1.1751935571078382,0.1698178934496409,1.7089459418696067,-1.975410552938287
3,328
Synthesis of dna
21
85
3.63247
0.000281
P28070,P56282,P25788,O75832,Q14181,P28072,P51530,P49721,Q9Y619,Q14566,O14818,Q96DE5,P41440,Q9NR33,Q16763,P49720,Q9UJX6,P20618,Q92530,Q99436,P60900
Processes and pathways
Reactome Pathways
msigdb_reactome
1,4,260,380,143,17,401,25,26,28,396,161,288,40,41,70,212,80,360,362,108
828,3121,1179,396,1500,1134,2820,380,2908,2155,2579,2205,2090,426,80,1037,768,2207,260,1239,1981,2092,1,17,804,2940,1817,1765,2029,2030,999,3003,2487,1925,2489,1984,1875,1876,288,2543,2389,2888,3113,1572,70,25,1641,401,1987,1084,4,108,772,1461,1646,1825,1648,652,2500,1886,3025,2553,143,28,2917,1779,41,360,161,362,1729,899,2414,2361,40,1733,3254,2070,906,724,212,596,1175,726,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.1448904124117295,-0.6468138089434564,0.821546325140021,-0.7204036003306101,-0.3019154331601609,-0.49929362365311203,-0.326629498975423,-0.2771896156285405,0.7460041320543394,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.22770296967824383,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.7449078178129339,-0.15338637233363414,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,0.21970488141706138,-0.8183422763589453,-0.4500213613594855,-0.20294226174328334,-0.4500213613594855,-0.22770296967824383,-0.17817004308089993,-0.17817004308089993,1.0234085363357603,-0.47466359244301676,-0.4007005636256563,-0.6958864768820794,-0.9892231160423917,-0.05413831981279846,2.452016645869307,3.878282602092929,-0.07896722474974421,0.7963560132112784,-0.22770296967824383,0.1698178934496409,6.439542763092297,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.4500213613594855,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,1.6324641866784928,3.799957938157529,-0.7204036003306101,-0.1285913075228445,3.253341222402017,0.8719554923012351,1.479728647315875,0.8719554923012351,-0.10378490605866271,0.2946146812215758,-0.4007005636256563,-0.37602212714831224,3.3832205189442597,-0.10378490605866271,-1.7135074577953051,-0.25245210761188314,0.2946146812215758,0.4196726296872428,1.225860974980719,0.5449858631910435,0.1448904124117295,0.4196726296872428,3.85216794801156
3,328
Regulation of alternative mrna splicing via spliceosome
19
33
3.619935
0.000295
P98175,Q13247,P51116,O75525,P09651,Q92841,P51114,Q9BWF3,Q06787,Q15007,P38159,Q8IY67,P62995,Q96MU7,P52756,Q07666,Q15287,P17844,Q9UHX1
Processes and pathways
GO Biological process
msigdb_gobp
136,275,271,157,415,169,293,435,429,182,194,333,328,205,217,482,357,370,378
1550,157,415,1189,370,1453,1571,194,2390,293,271,918,217,328,136,2107,1885,429,482,275,182,357,2406,333,1364,169,2124,205,633,435,378,1334,514
-0.05413831981279846,1.479728647315875,0.7711752687730454,0.11997367421113542,0.8467461646808371,-0.00444706101777177,-0.05413831981279846,1.3019290187854229,-0.4007005636256563,0.9981430916099898,1.0486832017281793,0.2696342378209103,1.2005227817735866,0.9224024553533663,1.6579497333950177,-0.2771896156285405,-0.17817004308089993,0.7460041320543394,0.6705487758636702,1.0486832017281793,1.352685259282614,0.8719554923012351,-0.4007005636256563,0.9224024553533663,0.04528843208172267,1.428885264813286,-0.2771896156285405,1.2512081018821377,0.4948303001812229,0.7460041320543394,0.8467461646808371,0.07017263198353871,0.6454164794914127
3,328
S phase
22
96
3.619845
0.000295
P28070,P56282,P25788,O75832,Q14181,P28072,P51530,P49721,Q9Y619,Q14566,O14818,Q96DE5,P41440,Q9NR33,Q16763,P49720,Q9UJX6,P20618,Q29RF7,Q92530,Q99436,P60900
Processes and pathways
Reactome Pathways
msigdb_reactome
1,4,260,380,143,17,401,25,26,28,396,161,288,40,41,70,212,80,347,360,362,108
828,3121,1179,396,1500,1134,1751,2820,380,2908,836,2155,2579,2205,2090,426,80,1037,768,2207,260,1239,1981,2092,1,17,804,2940,1817,839,1765,2029,2030,999,3003,2487,1925,2489,1984,1875,1876,288,2543,2389,2888,3113,1572,70,25,1641,917,401,1987,1084,4,108,772,1461,1646,1825,1648,652,2500,1886,3025,2553,143,28,1525,2917,1779,41,347,888,1534,2649,360,161,362,1729,899,2414,2361,40,1733,1961,3254,2070,906,724,212,596,1175,1686,726,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.1448904124117295,-0.1285913075228445,-0.6468138089434564,0.821546325140021,-0.7204036003306101,0.3196055701226996,-0.3019154331601609,-0.49929362365311203,-0.326629498975423,-0.2771896156285405,0.7460041320543394,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.22770296967824383,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.7449078178129339,-0.15338637233363414,0.3196055701226996,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,0.21970488141706138,-0.8183422763589453,-0.4500213613594855,-0.20294226174328334,-0.4500213613594855,-0.22770296967824383,-0.17817004308089993,-0.17817004308089993,1.0234085363357603,-0.47466359244301676,-0.4007005636256563,-0.6958864768820794,-0.9892231160423917,-0.05413831981279846,2.452016645869307,3.878282602092929,-0.07896722474974421,0.2696342378209103,0.7963560132112784,-0.22770296967824383,0.1698178934496409,6.439542763092297,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.4500213613594855,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,1.6324641866784928,3.799957938157529,-0.029298246881930074,-0.7204036003306101,-0.1285913075228445,3.253341222402017,0.8971742688101305,0.2946146812215758,-0.029298246881930074,-0.5239113880300665,0.8719554923012351,1.479728647315875,0.8719554923012351,-0.10378490605866271,0.2946146812215758,-0.4007005636256563,-0.37602212714831224,3.3832205189442597,-0.10378490605866271,-0.20294226174328334,-1.7135074577953051,-0.25245210761188314,0.2946146812215758,0.4196726296872428,1.225860974980719,0.5449858631910435,0.1448904124117295,-0.07896722474974421,0.4196726296872428,3.85216794801156
3,328
Dna replication
22
91
3.589016
0.000332
P28070,P56282,P25788,O75832,Q14181,P28072,P51530,P49721,Q9Y619,Q14566,O14818,Q96DE5,P41440,Q9NR33,Q16763,P49720,Q9UJX6,P20618,P52294,Q92530,Q99436,P60900
Processes and pathways
Reactome Pathways
msigdb_reactome
1,4,260,380,143,17,401,25,26,28,396,161,288,40,41,70,212,80,216,360,362,108
828,3121,1179,396,1500,1134,1229,2820,380,2908,2155,2579,2580,2205,2090,426,80,1037,768,2207,260,1239,1981,2092,1,17,804,2940,1817,1765,2029,2030,999,3003,2487,1925,2489,1984,1875,1876,288,2543,2389,2888,3113,1572,70,25,1641,401,1987,216,1084,4,108,772,1461,1646,1825,2790,1648,652,2500,1886,3025,2553,143,28,2713,2917,1779,41,1593,360,161,362,1729,899,2414,2361,40,1733,3254,2070,906,724,212,596,1175,726,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.1448904124117295,0.09506773013462308,-0.6468138089434564,0.821546325140021,-0.7204036003306101,-0.3019154331601609,-0.49929362365311203,-0.49929362365311203,-0.326629498975423,-0.2771896156285405,0.7460041320543394,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.22770296967824383,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.7449078178129339,-0.15338637233363414,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,0.21970488141706138,-0.8183422763589453,-0.4500213613594855,-0.20294226174328334,-0.4500213613594855,-0.22770296967824383,-0.17817004308089993,-0.17817004308089993,1.0234085363357603,-0.47466359244301676,-0.4007005636256563,-0.6958864768820794,-0.9892231160423917,-0.05413831981279846,2.452016645869307,3.878282602092929,-0.07896722474974421,0.7963560132112784,-0.22770296967824383,1.2005227817735866,0.1698178934496409,6.439542763092297,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.6222584106680328,-0.07896722474974421,0.46976760864997624,-0.4500213613594855,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,1.6324641866784928,3.799957938157529,-0.5731098445670545,-0.7204036003306101,-0.1285913075228445,3.253341222402017,-0.05413831981279846,0.8719554923012351,1.479728647315875,0.8719554923012351,-0.10378490605866271,0.2946146812215758,-0.4007005636256563,-0.37602212714831224,3.3832205189442597,-0.10378490605866271,-1.7135074577953051,-0.25245210761188314,0.2946146812215758,0.4196726296872428,1.225860974980719,0.5449858631910435,0.1448904124117295,0.4196726296872428,3.85216794801156
3,328
Apc c mediated degradation of cell cycle proteins
15
54
3.57627
0.000349
P28070,Q92530,Q99436,P49720,P25788,O75832,Q16763,P60900,Q9UJX6,P20618,P28072,O60566,P49721,O14818,Q96DE5
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,41,108,212,80,17,207,25,396,161
828,3121,1179,396,1500,1974,207,380,1401,2087,2205,426,80,768,2207,260,1239,2092,1,17,804,1817,2489,2543,2389,70,25,1987,1083,1084,108,772,1461,1646,1825,1648,652,1886,3025,2553,2917,1779,41,360,161,362,1729,2361,2070,906,724,212,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,-0.22770296967824383,1.225860974980719,0.821546325140021,0.02041518328356238,-0.2771896156285405,-0.326629498975423,0.7460041320543394,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.15338637233363414,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,-0.7204036003306101,-0.1285913075228445,3.253341222402017,0.8719554923012351,1.479728647315875,0.8719554923012351,-0.10378490605866271,-0.37602212714831224,-0.25245210761188314,0.2946146812215758,0.4196726296872428,1.225860974980719,0.5449858631910435,0.1448904124117295
3,328
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
13
47
3.571825
0.000355
P28070,Q92530,Q99436,P49720,P25788,O75832,Q16763,P60900,Q9UJX6,P20618,P28072,P49721,Q96DE5
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,41,108,212,80,17,25,161
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,1817,2489,2543,2389,70,25,1987,1083,1084,108,772,1461,1646,1825,652,1886,3025,2917,1779,41,360,161,362,1729,2361,2070,906,724,212,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.15338637233363414,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.8427941071748147,-0.7204036003306101,-0.1285913075228445,3.253341222402017,0.8719554923012351,1.479728647315875,0.8719554923012351,-0.10378490605866271,-0.37602212714831224,-0.25245210761188314,0.2946146812215758,0.4196726296872428,1.225860974980719,0.5449858631910435,0.1448904124117295
3,328
Negative regulation of mrna metabolic process
22
47
3.514147
0.000441
P98175,Q13148,Q13242,Q13247,Q14103,Q07021,P67809,Q06787,P16989,Q99729,Q15717,Q16629,P38159,P22626,Q92804,O60506,P26368,P35637,P61978,Q15287,Q14011,O75150
Processes and pathways
GO Biological process
msigdb_gobp
136,525,406,275,538,168,174,429,180,454,589,590,194,198,74,322,99,107,605,357,124,252
1914,1497,1550,322,252,2906,2080,834,1506,180,625,198,99,1453,107,194,605,174,136,2107,429,168,1520,2223,1774,525,1829,406,275,124,538,357,589,2897,590,2334,1050,1531,2044,2715,2123,74,454,1849,756,1327,1334
-0.20294226174328334,-0.029298246881930074,-0.05413831981279846,0.9224024553533663,1.099260047132413,-0.7204036003306101,-0.2771896156285405,0.3196055701226996,-0.029298246881930074,1.352685259282614,0.4948303001812229,1.2765641279126316,2.06683835096759,-0.00444706101777177,1.9900137899010935,1.3019290187854229,0.5199030665002794,1.3780765416953078,1.6579497333950177,-0.2771896156285405,0.7460041320543394,1.428885264813286,-0.029298246881930074,-0.326629498975423,-0.1285913075228445,0.6202939974103107,-0.15338637233363414,0.7963560132112784,1.0486832017281793,1.7599754364752334,0.5951813720548296,0.8719554923012351,0.5449858631910435,-0.6958864768820794,0.5449858631910435,-0.37602212714831224,0.19475606654496544,-0.029298246881930074,-0.25245210761188314,-0.5731098445670545,-0.2771896156285405,2.42628438755721,0.7208426436394583,-0.15338637233363414,0.39464043317762726,0.07017263198353871,0.07017263198353871
3,328
Deubiquitination
20
94
3.490532
0.000482
P28070,O95630,P21796,P25788,O75832,P28072,Q96FW1,P54725,P49721,P25054,O14818,P45880,Q15018,Q8NB78,P49720,P20618,Q92530,Q99436,P60900,Q92783
Processes and pathways
Reactome Pathways
msigdb_reactome
1,5,7,260,380,17,280,273,25,399,396,46,60,61,70,80,360,362,108,254
828,3121,1179,396,3158,1285,1500,2296,1136,380,1627,5,2616,1814,1401,1348,2205,426,80,7,399,768,2207,260,1239,2092,1,17,804,2489,956,2543,46,1193,2389,70,25,2098,1987,1145,3045,273,1356,1084,2219,108,772,1043,1461,1646,1825,652,1886,3025,584,2636,1713,2226,2917,1779,60,2331,2115,2506,1528,541,2233,1321,61,1898,360,254,2125,2859,1426,280,1055,2833,362,1729,978,1732,1964,1613,1024,596,1175,3143,2072,3206,2875,640,2017,1623
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-1.135155613795873,0.07017263198353871,-0.029298246881930074,-0.37602212714831224,0.1448904124117295,0.821546325140021,-0.07896722474974421,6.0400653546981165,-0.5239113880300665,-0.15338637233363414,0.02041518328356238,0.04528843208172267,-0.326629498975423,0.7460041320543394,2.323431235195337,5.641770539863659,0.7963560132112784,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,0.24466428827712608,-0.47466359244301676,2.9940993730239627,0.11997367421113542,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.2771896156285405,-0.22770296967824383,0.1448904124117295,-0.8672326458632422,1.0486832017281793,0.04528843208172267,0.1698178934496409,-0.326629498975423,1.9644215771503513,0.36961849331166047,0.19475606654496544,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.8427941071748147,0.5449858631910435,-0.5239113880300665,-0.10378490605866271,-0.326629498975423,-0.7204036003306101,-0.1285913075228445,2.555020827363027,-0.37602212714831224,-0.2771896156285405,-0.4500213613594855,-0.029298246881930074,0.5951813720548296,-0.326629498975423,0.07017263198353871,2.555020827363027,-0.17817004308089993,0.8719554923012351,1.099260047132413,-0.2771896156285405,-0.6713565219046082,0.02041518328356238,1.0486832017281793,0.19475606654496544,-0.6468138089434564,0.8719554923012351,-0.10378490605866271,0.24466428827712608,-0.10378490605866271,-0.20294226174328334,-0.05413831981279846,0.21970488141706138,0.5449858631910435,0.1448904124117295,-1.0622526018002627,-0.25245210761188314,-1.3289262534598685,-0.6713565219046082,0.4948303001812229,-0.22770296967824383,-0.05413831981279846
3,328
Signaling by notch4
11
43
3.477574
0.000506
P28070,Q92530,Q92542,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,298,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,839,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,1044,1648,652,1886,1465,2553,1779,360,298,362,1729,596,1175,1028
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.3196055701226996,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.19475606654496544,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.00444706101777177,-0.47466359244301676,-0.1285913075228445,0.8719554923012351,0.9981430916099898,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295,0.21970488141706138
3,328
Antigen processing cross presentation
14
54
3.477435
0.000506
O15111,P28070,Q9UIQ6,Q9UBG0,Q92530,P49720,Q99436,P25788,O75832,P60900,P20618,P28072,Q03518,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
126,1,35,266,360,70,362,260,380,108,80,17,355,25
2075,828,3121,1179,396,2425,126,1500,1558,380,1034,699,674,953,2205,80,768,2207,260,1239,1763,2092,1,17,804,2259,2489,2543,2389,70,25,1987,1084,2850,108,772,3161,1461,1646,1825,355,652,1202,1886,2917,1779,360,362,1729,266,35,596,1175,1623
-0.2771896156285405,0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.42536699660255867,1.7344565433373995,-0.029298246881930074,-0.05413831981279846,0.821546325140021,0.19475606654496544,0.4196726296872428,0.44471503673584983,0.24466428827712608,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.1285913075228445,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.3513317511686248,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,-0.6713565219046082,1.9644215771503513,0.36961849331166047,-1.135155613795873,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.8719554923012351,0.46976760864997624,0.11997367421113542,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,1.0739670508651682,3.46122934532905,0.5449858631910435,0.1448904124117295,-0.05413831981279846
3,328
Downstream signaling events of b cell receptor bcr
12
45
3.454332
0.000552
O15111,P28070,Q92530,Q99436,P49720,P25788,O75832,P62942,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
126,1,360,362,70,260,380,8,108,80,17,25
828,3121,1179,396,2425,126,1500,380,2205,3279,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,8,1648,652,2635,1886,2553,2917,1779,360,362,1729,596,1175,1623
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.42536699660255867,1.7344565433373995,-0.029298246881930074,0.821546325140021,-0.326629498975423,-2.022793354150014,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,5.562256959577436,-0.07896722474974421,0.46976760864997624,-0.5239113880300665,-0.17817004308089993,-0.47466359244301676,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295,-0.05413831981279846
3,328
Cell cycle checkpoints
28
147
3.453985
0.000552
P28070,Q8NFH4,P25788,O75832,O96028,Q9UQ84,Q8NBT2,P28072,P30154,Q96EA4,P51530,Q53HL2,P49721,Q9Y619,Q14566,O14818,Q96DE5,Q16763,P30153,Q02224,P20248,P49720,Q9UJX6,P20618,O60566,Q92530,Q99436,P60900
Processes and pathways
Reactome Pathways
msigdb_reactome
1,263,260,380,11,139,278,17,145,149,401,155,25,26,28,396,161,41,292,306,426,70,212,80,207,360,362,108
728,828,3121,1179,948,441,396,1744,1132,1500,763,1399,1974,1134,207,2374,2532,671,2820,380,2379,11,1814,1401,2087,2579,2580,2205,426,80,1037,768,2207,260,1239,1076,1981,2092,1,17,804,292,145,1817,2707,1241,1765,2029,2030,999,3003,2487,2489,956,1875,1876,583,2847,2543,1702,2389,70,25,1641,1820,1244,3229,401,1987,874,1083,959,1084,841,108,1196,772,1197,1461,1646,773,1825,2790,1044,1519,306,877,652,743,2916,1886,1775,2792,2752,28,1942,2894,2917,3009,1779,924,1309,41,1099,155,1011,1593,2177,278,3051,263,1948,360,3132,1666,3061,161,149,2126,1367,362,1729,2688,2354,790,2361,1541,1732,1222,823,1964,1613,2014,2466,3254,2070,906,724,212,596,1175,139,984,2142,26,1065,1178
0.39464043317762726,0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.24466428827712608,0.7208426436394583,0.7963560132112784,-0.1285913075228445,0.1448904124117295,-0.029298246881930074,0.36961849331166047,0.02041518328356238,-0.22770296967824383,0.1448904124117295,1.225860974980719,-0.4007005636256563,-0.47466359244301676,0.44471503673584983,-0.6468138089434564,0.821546325140021,-0.4007005636256563,4.927949599884505,-0.15338637233363414,0.02041518328356238,-0.2771896156285405,-0.49929362365311203,-0.49929362365311203,-0.326629498975423,0.7460041320543394,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,0.1698178934496409,-0.22770296967824383,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.9981430916099898,1.6069870522177834,-0.15338637233363414,-0.5731098445670545,0.09506773013462308,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,0.21970488141706138,-0.8183422763589453,-0.4500213613594855,-0.4500213613594855,0.24466428827712608,-0.17817004308089993,-0.17817004308089993,0.5449858631910435,-0.6713565219046082,-0.47466359244301676,-0.10378490605866271,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.07896722474974421,-0.15338637233363414,0.09506773013462308,-1.5217291046799297,0.7963560132112784,-0.22770296967824383,0.2946146812215758,0.1698178934496409,0.24466428827712608,0.1698178934496409,0.3196055701226996,1.9644215771503513,0.11997367421113542,0.36961849331166047,0.11997367421113542,-0.00444706101777177,-0.07896722474974421,0.36961849331166047,-0.15338637233363414,-0.6222584106680328,0.19475606654496544,-0.029298246881930074,0.9728869047846684,0.2946146812215758,0.46976760864997624,0.39464043317762726,-0.7204036003306101,-0.17817004308089993,-0.1285913075228445,-0.6222584106680328,-0.5976903988876788,3.799957938157529,-0.20294226174328334,-0.6958864768820794,-0.7204036003306101,-0.8183422763589453,-0.1285913075228445,0.2696342378209103,0.07017263198353871,3.253341222402017,0.1698178934496409,1.5051632549185123,0.21970488141706138,-0.05413831981279846,-0.3019154331601609,1.0486832017281793,-0.8672326458632422,1.0739670508651682,-0.20294226174328334,0.8719554923012351,-1.037923373617608,-0.07896722474974421,-0.8916578122719323,1.479728647315875,1.5560581431865503,-0.2771896156285405,0.04528843208172267,0.8719554923012351,-0.10378490605866271,-0.5485168178411735,-0.37602212714831224,0.36961849331166047,-0.37602212714831224,-0.029298246881930074,-0.10378490605866271,0.11997367421113542,0.3446068566314095,-0.20294226174328334,-0.05413831981279846,-0.22770296967824383,-0.42536699660255867,-1.7135074577953051,-0.25245210761188314,0.2946146812215758,0.4196726296872428,1.225860974980719,0.5449858631910435,0.1448904124117295,1.6579497333950177,0.24466428827712608,-0.2771896156285405,3.85216794801156,0.19475606654496544,0.1448904124117295
3,328
Diseases of signal transduction by growth factor receptors and second messengers
32
152
3.450817
0.000559
P28070,O15111,P06753,P78536,P19388,P62942,P25788,O75832,P28072,P30154,P62993,P49721,P25054,O14818,Q92542,Q92734,P51114,P30153,Q92614,Q07866,O43252,Q96B36,P49720,P20618,Q6UN15,O95684,Q92530,Q99436,P60900,P67936,P42224,O95429
Processes and pathways
Reactome Pathways
msigdb_reactome
1,126,132,386,383,8,260,380,17,145,274,25,399,396,298,299,293,292,51,307,312,336,70,80,348,222,360,362,108,110,371,116
2975,828,3121,1396,1179,396,126,495,1552,1500,312,2935,2533,380,1137,2149,116,222,1345,910,911,132,1185,954,700,1507,2205,1870,3002,1236,383,80,3255,1349,399,768,2207,260,1239,998,2310,3126,2092,1,17,804,1078,2093,292,145,1874,839,1240,1241,955,1295,3166,1404,499,2489,2542,1639,371,1877,2543,1879,2389,1881,1985,70,25,1820,2941,1821,917,293,2494,1987,1084,2219,2496,108,772,2711,1461,1646,1825,2101,2589,1087,8,274,1578,1648,110,386,1199,2448,607,2108,1654,652,307,2270,1886,2552,2272,1888,2750,1465,2553,963,2894,1415,2917,1779,1309,778,1098,1833,348,886,2001,2829,418,1837,813,1898,360,298,51,299,2765,336,488,2460,362,1729,2835,1270,1376,2526,2191,2288,1679,983,688,493,596,1175,3144,2665
-0.7938772325700006,0.3196055701226996,-1.0135801824627193,0.02041518328356238,0.11997367421113542,0.7963560132112784,1.7344565433373995,0.6454164794914127,-0.05413831981279846,-0.029298246881930074,0.9476400134093361,-0.7449078178129339,-0.47466359244301676,0.821546325140021,0.1448904124117295,-0.3019154331601609,1.8365815711642068,1.1751935571078382,0.04528843208172267,0.2696342378209103,0.2696342378209103,1.6834436618783488,0.11997367421113542,0.24466428827712608,0.4196726296872428,-0.029298246881930074,-0.326629498975423,-0.17817004308089993,-0.8183422763589453,0.09506773013462308,0.821546325140021,2.323431235195337,-1.7851473898187116,0.04528843208172267,0.7963560132112784,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,0.21970488141706138,-0.37602212714831224,-1.037923373617608,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.1698178934496409,-0.2771896156285405,0.9981430916099898,1.6069870522177834,-0.17817004308089993,0.3196055701226996,0.09506773013462308,0.09506773013462308,0.24466428827712608,0.07017263198353871,-1.159428089317279,0.02041518328356238,0.6454164794914127,-0.4500213613594855,-0.47466359244301676,-0.07896722474974421,0.8467461646808371,-0.17817004308089993,-0.47466359244301676,-0.17817004308089993,-0.4007005636256563,-0.17817004308089993,-0.22770296967824383,2.452016645869307,3.878282602092929,-0.15338637233363414,-0.7449078178129339,-0.15338637233363414,0.2696342378209103,0.9981430916099898,-0.4500213613594855,-0.22770296967824383,0.1698178934496409,-0.326629498975423,-0.4500213613594855,1.9644215771503513,0.36961849331166047,-0.5731098445670545,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.2771896156285405,-0.49929362365311203,0.1698178934496409,5.562256959577436,1.0486832017281793,-0.05413831981279846,-0.07896722474974421,1.9132612789115413,0.821546325140021,0.11997367421113542,-0.42536699660255867,0.5199030665002794,-0.2771896156285405,-0.07896722474974421,0.46976760864997624,0.9728869047846684,-0.3513317511686248,-0.17817004308089993,-0.47466359244301676,-0.3513317511686248,-0.17817004308089993,-0.5976903988876788,-0.00444706101777177,-0.47466359244301676,0.24466428827712608,-0.6958864768820794,0.02041518328356238,-0.7204036003306101,-0.1285913075228445,0.07017263198353871,0.36961849331166047,0.1698178934496409,-0.15338637233363414,0.8971742688101305,0.2946146812215758,-0.22770296967824383,-0.6468138089434564,0.7711752687730454,-0.15338637233363414,0.3446068566314095,-0.17817004308089993,0.8719554923012351,0.9981430916099898,2.8905991952326877,0.9981430916099898,-0.5976903988876788,0.9224024553533663,0.6705487758636702,-0.42536699660255867,0.8719554923012351,-0.10378490605866271,-0.6468138089434564,0.09506773013462308,0.04528843208172267,-0.4500213613594855,-0.3019154331601609,-0.3513317511686248,-0.07896722474974421,0.24466428827712608,0.44471503673584983,0.6705487758636702,0.5449858631910435,0.1448904124117295,-1.0622526018002627,-0.5239113880300665
3,328
Signaling by the b cell receptor bcr
13
47
3.446457
0.000568
O15111,P28070,Q92530,Q99436,P49720,P25788,O75832,P62942,P60900,P20618,P28072,P62993,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
126,1,360,362,70,260,380,8,108,80,17,274,25
828,3121,1179,396,2425,126,1500,2818,380,2205,3279,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,8,274,1648,652,2635,1886,2553,2917,1779,360,362,1729,596,1175,1623
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.42536699660255867,1.7344565433373995,-0.029298246881930074,-0.6468138089434564,0.821546325140021,-0.326629498975423,-2.022793354150014,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,5.562256959577436,1.0486832017281793,-0.07896722474974421,0.46976760864997624,-0.5239113880300665,-0.17817004308089993,-0.47466359244301676,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295,-0.05413831981279846
3,328
Orc1 removal from chromatin
13
50
3.441647
0.000578
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721,Q9Y619,Q14566,O14818
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25,26,28,396
828,3121,1179,396,1500,1134,380,2205,426,80,1037,768,2207,260,1239,2092,1,17,804,1765,2029,2030,2489,2543,2389,70,25,1641,1987,1084,108,772,1461,1646,1825,1648,652,1886,3025,2553,28,2917,1779,360,362,1729,3254,596,1175,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.1448904124117295,0.821546325140021,-0.326629498975423,0.7460041320543394,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.07896722474974421,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,3.799957938157529,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,-1.7135074577953051,0.5449858631910435,0.1448904124117295,3.85216794801156
3,328
Degradation of beta catenin by the destruction complex
13
50
3.438413
0.000585
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P30153,P20618,P30154,P28072,P49721,P25054
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,292,80,145,17,25,399
828,3121,1179,396,1500,380,2205,80,399,768,2207,260,1239,2092,1,17,804,292,145,1295,2489,2543,2389,1881,70,25,917,1987,1084,2496,108,772,1461,1646,1825,1648,652,1886,2552,1888,2553,2894,2917,1779,1309,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.7963560132112784,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.9981430916099898,1.6069870522177834,0.07017263198353871,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,-0.17817004308089993,2.452016645869307,3.878282602092929,0.2696342378209103,-0.22770296967824383,0.1698178934496409,-0.4500213613594855,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.47466359244301676,-0.17817004308089993,-0.47466359244301676,-0.6958864768820794,-0.7204036003306101,-0.1285913075228445,0.07017263198353871,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Uch proteinases
11
45
3.411529
0.000646
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721,Q8NB78
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25,61
828,3121,1179,396,1285,1500,380,2616,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,2098,1987,1084,108,772,1461,1646,1825,652,1886,2917,1779,2506,61,360,362,1729,596,1175,2072,640,2017
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,0.07017263198353871,-0.029298246881930074,0.821546325140021,-0.5239113880300665,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.2771896156285405,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,-0.4500213613594855,2.555020827363027,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295,-0.25245210761188314,0.4948303001812229,-0.22770296967824383
3,328
protease
12
42
3.379597
0.000726
P28070,P78536,Q99436,P49720,P25788,P60900,P20618,P28072,O75976,Q9UJ14,P49721,P42574
Functions
Panther Protein class
panther_protein_class
1,386,362,70,260,108,80,17,213,91,25,153
3121,396,1500,213,2432,2205,80,768,2207,260,1239,2092,1,17,804,2489,153,1000,2543,2389,70,25,2165,1084,108,1461,1646,1825,386,1886,3009,2758,362,1729,2239,1379,2837,510,91,1175,2734,1618
-1.0135801824627193,0.7963560132112784,-0.029298246881930074,1.2005227817735866,-0.42536699660255867,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,1.5051632549185123,0.21970488141706138,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.3019154331601609,0.1698178934496409,1.9644215771503513,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.821546325140021,-0.17817004308089993,-0.8183422763589453,-0.5976903988876788,0.8719554923012351,-0.10378490605866271,-0.326629498975423,0.04528843208172267,-0.6468138089434564,0.6454164794914127,2.195037402551606,0.1448904124117295,-0.5731098445670545,-0.05413831981279846
3,328
Transcriptional regulation by runx3
10
42
3.370566
0.00075
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,1814,2205,80,1568,768,2207,260,1239,2092,1,17,804,1295,2489,583,2543,2492,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,1465,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.15338637233363414,-0.326629498975423,2.323431235195337,-0.05413831981279846,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.07017263198353871,-0.4500213613594855,0.5449858631910435,-0.47466359244301676,-0.4500213613594855,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.00444706101777177,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
The role of gtse1 in g2 m progression after g2 checkpoint
10
50
3.355624
0.000792
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,1184,1814,1401,1185,1292,2087,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1083,1084,108,772,1461,1646,1825,1709,652,1886,1046,2917,1779,924,360,362,1729,820,1168,2014,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,0.11997367421113542,-0.15338637233363414,0.02041518328356238,0.11997367421113542,0.07017263198353871,-0.2771896156285405,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.10378490605866271,0.46976760864997624,-0.17817004308089993,0.19475606654496544,-0.7204036003306101,-0.1285913075228445,0.2696342378209103,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.3446068566314095,0.1448904124117295,-0.22770296967824383,0.5449858631910435,0.1448904124117295
3,328
Proteasome complex
12
50
3.343463
0.000827
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P54725,Q8IWV7,P49721
Localization
GO Cellular component
msigdb_gocc
1,360,362,70,260,380,108,80,17,273,59,25
828,3121,1179,396,1500,1553,380,2779,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,3045,273,1356,1084,2219,108,772,1461,1646,1825,1827,652,1886,2917,1779,1156,2506,2451,59,360,362,1729,596,827,1175,2017
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,-0.05413831981279846,0.821546325140021,-0.6222584106680328,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,-0.8672326458632422,1.0486832017281793,0.04528843208172267,0.1698178934496409,-0.326629498975423,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.1448904124117295,-0.4500213613594855,-0.42536699660255867,2.5807905397318898,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.3446068566314095,0.1448904124117295,-0.22770296967824383
3,328
Degradation of dvl
11
39
3.333293
0.000858
P28070,Q92530,Q99436,P49720,P25788,O75832,O14641,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,352,108,80,17,25
828,3121,1179,352,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,1585,2917,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.8719554923012351,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.05413831981279846,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Rna splicing via transesterification reactions
75
189
3.331199
0.000865
Q99590,Q96RS0,P98175,O95391,Q9BWJ5,Q9BZJ0,Q96PK6,Q07955,P31943,Q13247,P62312,Q13242,P51116,O75525,Q14562,Q9Y3C6,Q8TBF4,Q96DF8,P09651,Q07021,Q92841,Q9UMS4,P51114,Q86V81,Q9BWF3,Q06787,Q7L014,Q15007,O43719,P08621,Q8WWY3,P51991,P78362,P31942,Q8IYB3,P52597,Q16629,P38159,P22626,P23246,Q13595,Q8IY67,P62995,O75533,Q96MU7,O75934,O60506,P54105,Q96C86,Q01081,O95400,P52756,Q96I25,Q15428,O60828,O43390,Q13243,Q96PU8,Q15427,P26368,Q07666,Q92945,P61978,P98179,Q13123,Q15287,Q86UA1,P17844,Q9Y5S9,Q9Y383,Q96T37,Q9UHX1,Q14011,P55769,P16383
Processes and pathways
GO Biological process
msigdb_gobp
255,661,136,521,13,413,411,405,148,275,150,406,271,157,33,423,420,422,415,168,169,571,293,175,435,429,559,182,551,552,716,449,314,188,452,313,590,194,198,701,709,333,328,697,205,577,322,705,748,345,88,217,750,244,341,340,374,488,613,99,482,361,605,111,608,357,505,370,514,513,633,378,124,253,624
1971,1550,2196,1690,3135,1973,340,2574,1749,1750,551,1693,1752,1287,322,341,1135,1181,2906,157,697,2081,577,992,1344,2082,521,88,834,2739,552,1071,733,415,2740,1402,1506,1189,624,370,2623,2026,198,701,99,1453,1982,1571,188,148,194,1038,2211,1352,1296,2390,293,271,918,449,1082,313,217,874,705,1823,253,1042,605,2396,150,3046,2100,2890,328,314,2679,136,111,2107,345,1885,429,168,482,405,1520,2223,2270,1774,1464,608,406,374,275,921,2328,1465,709,1998,124,964,33,182,883,2274,357,2853,613,244,1157,1008,590,1310,2406,2918,3176,1102,2757,966,3029,559,1594,2646,505,175,2715,333,452,1364,420,1791,1664,716,1727,2345,169,2124,1015,361,933,748,422,935,2127,750,205,411,488,661,1056,633,937,255,1849,1671,1538,435,13,413,2948,757,2057,3156,1171,1062,3151,796,2244,1616,1388,378,2069,1389,1739,3172,571,2814,2530,1334,2292,860,2195,513,1124,423,1226,2422,514
-0.22770296967824383,-0.05413831981279846,-0.326629498975423,-0.10378490605866271,-1.0622526018002627,-0.22770296967824383,0.8971742688101305,-0.49929362365311203,-0.1285913075228445,-0.1285913075228445,0.5700786462448547,-0.10378490605866271,-0.1285913075228445,0.07017263198353871,0.9224024553533663,0.8971742688101305,0.1448904124117295,0.11997367421113542,-0.7204036003306101,1.479728647315875,0.4196726296872428,-0.2771896156285405,0.5449858631910435,0.21970488141706138,0.04528843208172267,-0.2771896156285405,0.6202939974103107,2.195037402551606,0.3196055701226996,-0.5976903988876788,0.5700786462448547,0.1698178934496409,0.39464043317762726,0.7711752687730454,-0.5976903988876788,0.02041518328356238,-0.029298246881930074,0.11997367421113542,0.4948303001812229,0.8467461646808371,-0.5239113880300665,-0.25245210761188314,1.2765641279126316,0.4196726296872428,2.06683835096759,-0.00444706101777177,-0.22770296967824383,-0.05413831981279846,1.3273027404887678,1.5815183607346968,1.3019290187854229,0.19475606654496544,-0.326629498975423,0.04528843208172267,0.07017263198353871,-0.4007005636256563,0.9981430916099898,1.0486832017281793,0.2696342378209103,0.7208426436394583,0.1698178934496409,0.9476400134093361,1.2005227817735866,0.2946146812215758,0.4196726296872428,-0.15338637233363414,1.099260047132413,0.19475606654496544,0.5199030665002794,-0.4007005636256563,1.5306064307689333,-0.8672326458632422,-0.2771896156285405,-0.6958864768820794,0.9224024553533663,0.9476400134093361,-0.5485168178411735,1.6579497333950177,1.887693249412294,-0.2771896156285405,0.8971742688101305,-0.17817004308089993,0.7460041320543394,1.428885264813286,0.6705487758636702,0.7963560132112784,-0.029298246881930074,-0.326629498975423,-0.3513317511686248,-0.1285913075228445,-0.00444706101777177,0.5199030665002794,0.7963560132112784,0.8467461646808371,1.0486832017281793,0.2696342378209103,-0.37602212714831224,-0.00444706101777177,0.4196726296872428,-0.22770296967824383,1.7599754364752334,0.24466428827712608,3.487245713042414,1.352685259282614,0.2946146812215758,-0.3513317511686248,0.8719554923012351,-0.6713565219046082,0.5199030665002794,1.1245621542194768,0.1448904124117295,0.21970488141706138,0.5449858631910435,0.07017263198353871,-0.4007005636256563,-0.7204036003306101,-1.1836861453389294,0.1698178934496409,-0.5976903988876788,0.24466428827712608,-0.8427941071748147,0.5700786462448547,-0.05413831981279846,-0.5239113880300665,0.6454164794914127,1.3780765416953078,-0.5731098445670545,0.9224024553533663,0.7208426436394583,0.04528843208172267,0.7711752687730454,-0.1285913075228445,-0.07896722474974421,0.4196726296872428,-0.10378490605866271,-0.37602212714831224,1.428885264813286,-0.2771896156285405,0.21970488141706138,0.8719554923012351,0.2696342378209103,0.39464043317762726,0.7711752687730454,0.2696342378209103,-0.2771896156285405,0.39464043317762726,1.2512081018821377,0.7963560132112784,0.6705487758636702,0.46976760864997624,0.19475606654496544,0.4948303001812229,0.2696342378209103,1.099260047132413,-0.15338637233363414,-0.07896722474974421,-0.029298246881930074,0.7460041320543394,4.690933619436888,0.7963560132112784,-0.7449078178129339,0.39464043317762726,-0.25245210761188314,-1.1108688125620438,0.1448904124117295,0.19475606654496544,-1.0865677781367193,0.36961849331166047,-0.326629498975423,-0.05413831981279846,0.04528843208172267,0.8467461646808371,-0.25245210761188314,0.04528843208172267,-0.10378490605866271,-1.159428089317279,0.5700786462448547,-0.6222584106680328,-0.4500213613594855,0.07017263198353871,-0.3513317511686248,0.3196055701226996,-0.3019154331601609,0.6454164794914127,0.1698178934496409,0.7711752687730454,0.11997367421113542,-0.4007005636256563,0.6454164794914127
3,328
Hedgehog ligand biogenesis
11
41
3.322069
0.000894
P28070,Q92530,P78536,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,386,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,1444,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,2219,108,772,1461,1646,1825,386,652,1886,2917,1779,360,362,1729,688,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.00444706101777177,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,-0.326629498975423,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.821546325140021,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.44471503673584983,0.5449858631910435,0.1448904124117295
3,328
Negative regulation of notch4 signaling
10
41
3.313136
0.000923
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,839,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,1044,1648,652,1886,2553,1779,360,362,1729,596,1175,1028
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.3196055701226996,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.19475606654496544,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.47466359244301676,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295,0.21970488141706138
3,328
Endoplasmic reticulum lumen
22
63
3.30642
0.000945
P78536,Q96AY3,P53634,O15460,P30533,Q9Y680,P10909,O60568,Q9BTY2,P20248,Q14257,P13674,P11047,O95881,Q7Z4H8,Q02818,Q32P28,Q9NWM8,O75718,Q9NZ08,O43852,Q8NBJ4
Localization
GO Cellular component
msigdb_gocc
386,137,142,140,400,156,29,286,434,426,65,63,69,197,464,76,86,87,92,230,123,390
574,3289,140,2775,123,286,92,2431,197,1444,1445,2154,29,69,1449,63,1816,1294,2309,426,2027,3126,1763,1142,1078,1351,2259,400,1298,142,1248,386,76,741,1414,65,1466,1155,2402,844,86,1357,464,1052,658,390,2965,593,1164,137,1952,1603,1956,434,492,87,3272,2417,230,3068,2934,1688,156
0.5449858631910435,-2.282029353080064,1.6324641866784928,-0.6222584106680328,1.7599754364752334,1.0234085363357603,2.169381905284358,-0.42536699660255867,1.2765641279126316,-0.00444706101777177,-0.00444706101777177,-0.3019154331601609,3.721691432884529,2.452016645869307,-0.00444706101777177,2.503503755234874,-0.15338637233363414,0.07017263198353871,-0.37602212714831224,0.7460041320543394,-0.25245210761188314,-1.037923373617608,-0.1285913075228445,0.1448904124117295,0.1698178934496409,0.04528843208172267,-0.3513317511686248,0.7963560132112784,0.07017263198353871,1.6324641866784928,0.09506773013462308,0.821546325140021,2.3748425857753057,0.39464043317762726,0.02041518328356238,2.503503755234874,-0.00444706101777177,0.1448904124117295,-0.4007005636256563,0.3196055701226996,2.220700690696464,0.04528843208172267,0.6956908444727835,0.19475606654496544,0.46976760864997624,0.821546325140021,-0.7693990539832007,0.5449858631910435,0.1448904124117295,1.6579497333950177,-0.20294226174328334,-0.05413831981279846,-0.20294226174328334,0.7460041320543394,0.6705487758636702,2.220700690696464,-1.9516911576123395,-0.4007005636256563,1.1751935571078382,-0.8916578122719323,-0.7204036003306101,-0.07896722474974421,1.5051632549185123
3,328
Cross presentation of soluble exogenous antigens endosomes
11
38
3.301185
0.000963
P28070,Q92530,Q9UBG0,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,266,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,2917,1779,360,362,1729,266,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,1.0739670508651682,0.5449858631910435,0.1448904124117295
3,328
Mrna splicing
52
148
3.294252
0.000987
P19388,O95391,Q9BWJ5,Q9BZJ0,Q9BUJ2,Q07955,P31943,Q13247,P62312,Q92733,Q13242,Q14103,Q9Y3C6,Q8TBF4,P09651,Q9UMS4,P67809,Q86V81,Q8IWZ8,Q7L014,P08621,P51991,Q8N684,Q15717,P52597,Q16629,Q8IYB3,P38159,P22626,O94992,P62995,O75934,P55795,Q6UN15,Q01081,O95400,P52756,O60828,O43390,Q13243,Q15427,P26368,P35637,Q5KU26,P61978,Q15287,Q9Y5S9,P17844,Q15428,Q9UHX1,P55769,P16383
Processes and pathways
Reactome Pathways
msigdb_reactome
383,521,13,413,282,405,148,275,150,151,406,538,423,420,415,571,174,175,433,559,552,449,453,589,313,590,452,194,198,201,328,577,218,348,345,88,217,341,340,374,613,99,107,358,605,357,514,370,244,378,253,624
1130,1552,2372,3135,1973,340,2574,1749,1750,2020,1693,1752,341,1135,2906,697,2081,577,764,992,1344,201,521,88,834,2739,552,1071,733,415,2740,1402,1507,1189,624,370,1236,383,198,1349,99,1453,1874,148,677,1404,107,194,2211,1352,1296,1928,449,1082,313,217,253,218,605,2396,150,3046,2100,2890,2101,1087,328,174,2679,2107,345,1885,1937,1938,405,1520,2223,2270,2501,1464,1828,1829,406,374,275,921,1465,538,2274,357,1716,1096,2853,613,244,1157,1008,589,590,3176,358,3029,348,559,1594,1213,175,657,1012,433,2342,452,453,420,1792,716,817,2345,151,1728,1015,933,935,750,937,282,1671,13,1058,2997,413,757,3156,1171,3151,2244,1616,378,1390,3172,571,2814,2530,2292,2195,1124,423,514
0.1448904124117295,-0.05413831981279846,-0.4007005636256563,-1.0622526018002627,-0.22770296967824383,0.8971742688101305,-0.49929362365311203,-0.1285913075228445,-0.1285913075228445,-0.25245210761188314,-0.10378490605866271,-0.1285913075228445,0.8971742688101305,0.1448904124117295,-0.7204036003306101,0.4196726296872428,-0.2771896156285405,0.5449858631910435,0.36961849331166047,0.21970488141706138,0.04528843208172267,1.2512081018821377,0.6202939974103107,2.195037402551606,0.3196055701226996,-0.5976903988876788,0.5700786462448547,0.1698178934496409,0.39464043317762726,0.7711752687730454,-0.5976903988876788,0.02041518328356238,-0.029298246881930074,0.11997367421113542,0.4948303001812229,0.8467461646808371,0.09506773013462308,0.821546325140021,1.2765641279126316,0.04528843208172267,2.06683835096759,-0.00444706101777177,-0.17817004308089993,1.5815183607346968,0.44471503673584983,0.02041518328356238,1.9900137899010935,1.3019290187854229,-0.326629498975423,0.04528843208172267,0.07017263198353871,-0.20294226174328334,0.7208426436394583,0.1698178934496409,0.9476400134093361,1.2005227817735866,1.099260047132413,1.2005227817735866,0.5199030665002794,-0.4007005636256563,1.5306064307689333,-0.8672326458632422,-0.2771896156285405,-0.6958864768820794,-0.2771896156285405,0.1698178934496409,0.9224024553533663,1.3780765416953078,-0.5485168178411735,-0.2771896156285405,0.8971742688101305,-0.17817004308089993,-0.20294226174328334,-0.20294226174328334,0.7963560132112784,-0.029298246881930074,-0.326629498975423,-0.3513317511686248,-0.4500213613594855,-0.00444706101777177,-0.15338637233363414,-0.15338637233363414,0.7963560132112784,0.8467461646808371,1.0486832017281793,0.2696342378209103,-0.00444706101777177,0.5951813720548296,-0.3513317511686248,0.8719554923012351,-0.10378490605866271,0.1698178934496409,-0.6713565219046082,0.5199030665002794,1.1245621542194768,0.1448904124117295,0.21970488141706138,0.5449858631910435,0.5449858631910435,-1.1836861453389294,0.8719554923012351,-0.8427941071748147,0.8971742688101305,0.5700786462448547,-0.05413831981279846,0.11997367421113542,1.3780765416953078,0.46976760864997624,0.21970488141706138,0.7460041320543394,-0.37602212714831224,0.7208426436394583,0.7208426436394583,0.7711752687730454,-0.1285913075228445,0.4196726296872428,0.3446068566314095,-0.37602212714831224,1.5306064307689333,-0.10378490605866271,0.21970488141706138,0.2696342378209103,0.2696342378209103,0.39464043317762726,0.2696342378209103,1.0486832017281793,-0.07896722474974421,4.690933619436888,0.19475606654496544,-0.7938772325700006,0.7963560132112784,0.39464043317762726,-1.1108688125620438,0.1448904124117295,-1.0865677781367193,-0.326629498975423,-0.05413831981279846,0.8467461646808371,0.04528843208172267,-1.159428089317279,0.5700786462448547,-0.6222584106680328,-0.4500213613594855,-0.3513317511686248,-0.3019154331601609,0.1698178934496409,0.7711752687730454,0.6454164794914127
3,328
Asymmetric localization of pcp proteins
11
39
3.28649
0.001014
P28070,Q92530,Q99436,P49720,P25788,O75832,O14641,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,352,108,80,17,25
828,3121,1179,352,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,2273,2917,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.8719554923012351,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.3513317511686248,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
G2 m checkpoints
9
86
3.269195
0.001079
P28070,P49720,O96028,P60900,P20618,P28072,P49721,Q9Y619,Q14566
Processes and pathways
Reactome Pathways
msigdb_reactome
1,70,11,108,80,17,25,26,28
828,3121,1179,948,396,1500,1134,2374,2532,2820,380,2379,11,1814,1401,2087,2579,2580,2205,80,1037,768,2207,260,1239,1076,1981,2092,1,17,804,2707,1241,1765,2029,2030,999,3003,2487,2489,956,1875,1876,2543,2389,70,25,1641,1244,401,1987,959,1084,108,1196,772,1197,1461,1646,773,1825,2790,1044,877,652,2916,1886,28,1942,2917,1779,1593,360,1666,362,1729,1732,1964,1613,2014,3254,596,1175,139,2142,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.24466428827712608,0.7963560132112784,-0.029298246881930074,0.1448904124117295,-0.4007005636256563,-0.47466359244301676,-0.6468138089434564,0.821546325140021,-0.4007005636256563,4.927949599884505,-0.15338637233363414,0.02041518328356238,-0.2771896156285405,-0.49929362365311203,-0.49929362365311203,-0.326629498975423,2.323431235195337,0.19475606654496544,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,0.1698178934496409,-0.22770296967824383,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.5731098445670545,0.09506773013462308,-0.1285913075228445,-0.25245210761188314,-0.25245210761188314,0.21970488141706138,-0.8183422763589453,-0.4500213613594855,-0.4500213613594855,0.24466428827712608,-0.17817004308089993,-0.17817004308089993,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.07896722474974421,0.09506773013462308,0.7963560132112784,-0.22770296967824383,0.24466428827712608,0.1698178934496409,1.9644215771503513,0.11997367421113542,0.36961849331166047,0.11997367421113542,-0.00444706101777177,-0.07896722474974421,0.36961849331166047,-0.15338637233363414,-0.6222584106680328,0.19475606654496544,0.2946146812215758,0.46976760864997624,-0.7204036003306101,-0.17817004308089993,3.799957938157529,-0.20294226174328334,-0.7204036003306101,-0.1285913075228445,-0.05413831981279846,0.8719554923012351,-0.07896722474974421,0.8719554923012351,-0.10378490605866271,-0.10378490605866271,-0.20294226174328334,-0.05413831981279846,-0.22770296967824383,-1.7135074577953051,0.5449858631910435,0.1448904124117295,1.6579497333950177,-0.2771896156285405,3.85216794801156
3,328
Hedgehog on state
10
42
3.263438
0.001101
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,1881,70,25,1987,1084,108,772,1461,1646,1825,652,1886,1585,2917,1779,2642,360,1368,362,1729,596,1175,727
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,-0.17817004308089993,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.05413831981279846,-0.7204036003306101,-0.1285913075228445,-0.5239113880300665,0.8719554923012351,0.04528843208172267,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295,0.4196726296872428
3,328
Peptidyl proline modification
13
34
3.260068
0.001114
Q9Y237,P13674,Q9BV86,P62942,Q96AY3,P26885,Q02790,O15460,Q32P28,Q9NWM8,Q9Y680,O75718,Q13526
Processes and pathways
GO Biological process
msigdb_gobp
394,63,134,8,137,103,316,140,86,87,156,92,290
3055,140,1749,92,1444,63,2027,103,865,1570,1039,1820,8,1412,316,1773,1152,554,290,1713,1526,86,1792,137,933,1952,134,3264,757,87,2814,394,423,156
-0.8916578122719323,1.6324641866784928,-0.1285913075228445,2.169381905284358,-0.00444706101777177,2.503503755234874,-0.25245210761188314,2.015614008083381,0.2946146812215758,-0.05413831981279846,0.19475606654496544,-0.15338637233363414,5.562256959577436,0.02041518328356238,0.9476400134093361,-0.1285913075228445,0.1448904124117295,0.5700786462448547,1.0234085363357603,-0.10378490605866271,-0.029298246881930074,2.220700690696464,-0.1285913075228445,1.6579497333950177,0.2696342378209103,-0.20294226174328334,1.6834436618783488,-1.9041971751685358,0.39464043317762726,2.220700690696464,-0.6222584106680328,0.821546325140021,0.7711752687730454,1.5051632549185123
3,328
Auf1 hnrnp d0 binds and destabilizes mrna
10
42
3.255418
0.001132
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2779,1402,1506,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,1462,652,1886,538,2917,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.6222584106680328,0.02041518328356238,-0.029298246881930074,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.00444706101777177,0.46976760864997624,-0.17817004308089993,0.5951813720548296,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Cdt1 association with the cdc6 orc origin complex
11
40
3.246081
0.00117
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721,Q9Y619
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25,26
828,3121,1179,396,1500,1134,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,2917,1779,360,362,1729,3254,596,1175,26
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.1448904124117295,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,-1.7135074577953051,0.5449858631910435,0.1448904124117295,3.85216794801156
3,328
Regulation of ras by gaps
10
38
3.24272
0.001184
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,1585,2917,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.05413831981279846,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Regulation of pten stability and activity
13
42
3.240627
0.001193
P28070,Q92530,Q9UNE7,Q99436,P49720,P25788,O75832,P67870,P60900,P20618,P28072,P49721,O14818
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,494,362,70,260,380,329,108,80,17,25,396
828,3121,1179,396,1500,380,474,2205,2843,80,768,2207,260,1239,2092,1,17,804,839,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,329,652,1886,2917,1779,360,362,1729,596,494,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,0.6705487758636702,-0.326629498975423,-0.6713565219046082,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.3196055701226996,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.9224024553533663,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.6705487758636702,0.1448904124117295
3,328
Regulation of runx3 expression and activity
10
37
3.23276
0.001226
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,583,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,0.5449858631910435,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Cyclin a cdk2 associated events at s phase entry
11
42
3.230325
0.001236
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721,O14818
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25,396
828,3121,1179,396,1500,380,836,2205,426,80,768,2207,260,1239,2092,1,17,804,839,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,1648,652,1886,3025,2553,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,0.3196055701226996,-0.326629498975423,0.7460041320543394,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.3196055701226996,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Scf skp2 mediated degradation of p27 p21
11
41
3.22588
0.001256
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721,O14818
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25,396
828,3121,1179,396,1500,380,836,2205,426,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,1648,652,1886,3025,2553,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,0.3196055701226996,-0.326629498975423,0.7460041320543394,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
G1 s dna damage checkpoints
11
42
3.225856
0.001256
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721,O14818
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25,396
828,3121,1179,948,396,1500,380,2379,1814,2205,426,80,768,2207,260,1239,2092,1,17,804,2489,583,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,2917,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.24466428827712608,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.4007005636256563,-0.15338637233363414,-0.326629498975423,0.7460041320543394,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,0.5449858631910435,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Endopeptidase activity
17
62
3.220252
0.001281
P28070,Q13043,P07858,Q92542,Q8TCT8,P49720,Q99436,Q9NZ08,P60900,P53634,P20618,P28072,Q5JRX3,Q9BXS4,P49721,O75844,P42574
Functions
GO Molecular function
msigdb_gomf
1,388,130,298,133,70,362,230,108,142,80,17,246,118,25,241,153
1031,2295,2079,241,1629,767,130,1631,1348,837,80,1761,1239,1,17,804,2209,2259,1818,153,1000,648,1193,2744,70,25,1145,3263,142,3045,108,1579,386,1305,388,1153,2226,1417,1257,246,1590,2233,133,3242,298,3246,717,2859,1426,1055,2833,2516,362,2995,2726,118,469,230,3143,640,1970,1282
0.19475606654496544,-0.37602212714831224,-0.2771896156285405,1.1245621542194768,-0.07896722474974421,0.36961849331166047,1.7089459418696067,-0.07896722474974421,0.04528843208172267,0.3196055701226996,2.323431235195337,-0.1285913075228445,0.09506773013462308,8.210394651537106,4.29697723951205,0.3446068566314095,-0.326629498975423,-0.3513317511686248,-0.15338637233363414,1.5051632549185123,0.21970488141706138,0.46976760864997624,0.11997367421113542,-0.5976903988876788,2.452016645869307,3.878282602092929,0.1448904124117295,-1.9041971751685358,1.6324641866784928,-0.8672326458632422,1.9644215771503513,-0.05413831981279846,0.821546325140021,0.07017263198353871,0.821546325140021,0.1448904124117295,-0.326629498975423,0.02041518328356238,0.09506773013462308,1.1245621542194768,-0.05413831981279846,-0.326629498975423,1.6834436618783488,-1.6177501613860807,0.9981430916099898,-1.6417145265685216,0.4196726296872428,-0.6713565219046082,0.02041518328356238,0.19475606654496544,-0.6468138089434564,-0.4500213613594855,0.8719554923012351,-0.7938772325700006,-0.5731098445670545,1.8365815711642068,0.6956908444727835,1.1751935571078382,-1.0622526018002627,0.4948303001812229,-0.20294226174328334,0.09506773013462308
3,328
Spliceosomal complex
50
131
3.215311
0.001303
Q12972,O95391,Q9BWJ5,Q9BZJ0,Q07955,P31943,P62312,Q9Y3C6,Q14562,Q8TBF4,Q96DF8,P09651,Q9UMS4,P67809,Q86V81,Q8IWZ8,O43719,P08621,Q8WWY3,P51991,P31942,Q8IYB3,P52597,P38159,P22626,Q5VTL8,Q13595,P62995,O75533,O75934,O60506,P54105,Q01081,P52756,Q96I25,O43390,Q15427,P26368,Q9H2H8,P61978,P98179,Q13123,Q86UA1,Q9Y5S9,P17844,Q9Y383,Q15428,Q14011,P55769,P16383
Localization
GO Cellular component
msigdb_gocc
654,521,13,413,405,148,150,423,33,420,422,415,571,174,175,433,551,552,716,449,188,452,313,194,198,72,709,328,697,577,322,705,345,217,750,340,613,99,757,605,111,608,505,514,370,513,244,124,253,624
2372,3135,1973,340,2574,1749,1750,551,1693,1752,322,1135,697,2081,577,992,1344,2082,521,834,2739,552,1071,733,415,2740,1402,1506,624,370,2026,198,99,188,148,194,2211,1352,1296,449,1082,313,217,705,1823,1410,253,605,2396,150,3046,2100,2890,328,174,111,2107,345,1885,405,1464,654,608,921,2328,1465,709,1998,124,33,2274,2896,2853,613,244,1157,1008,2406,3176,72,1102,966,3029,1594,505,175,433,452,420,1664,716,1535,817,2345,1425,1015,933,422,935,750,937,1671,1538,13,413,938,757,2057,3156,1171,1062,2192,3151,2244,2015,1616,2069,1389,1739,3172,571,2814,2016,2530,2292,860,2195,513,1124,423,514
-0.4007005636256563,-1.0622526018002627,-0.22770296967824383,0.8971742688101305,-0.49929362365311203,-0.1285913075228445,-0.1285913075228445,0.5700786462448547,-0.10378490605866271,-0.1285913075228445,0.9224024553533663,0.1448904124117295,0.4196726296872428,-0.2771896156285405,0.5449858631910435,0.21970488141706138,0.04528843208172267,-0.2771896156285405,0.6202939974103107,0.3196055701226996,-0.5976903988876788,0.5700786462448547,0.1698178934496409,0.39464043317762726,0.7711752687730454,-0.5976903988876788,0.02041518328356238,-0.029298246881930074,0.4948303001812229,0.8467461646808371,-0.25245210761188314,1.2765641279126316,2.06683835096759,1.3273027404887678,1.5815183607346968,1.3019290187854229,-0.326629498975423,0.04528843208172267,0.07017263198353871,0.7208426436394583,0.1698178934496409,0.9476400134093361,1.2005227817735866,0.4196726296872428,-0.15338637233363414,0.02041518328356238,1.099260047132413,0.5199030665002794,-0.4007005636256563,1.5306064307689333,-0.8672326458632422,-0.2771896156285405,-0.6958864768820794,0.9224024553533663,1.3780765416953078,1.887693249412294,-0.2771896156285405,0.8971742688101305,-0.17817004308089993,0.7963560132112784,-0.00444706101777177,0.46976760864997624,0.5199030665002794,0.2696342378209103,-0.37602212714831224,-0.00444706101777177,0.4196726296872428,-0.22770296967824383,1.7599754364752334,3.487245713042414,-0.3513317511686248,-0.6958864768820794,-0.6713565219046082,0.5199030665002794,1.1245621542194768,0.1448904124117295,0.21970488141706138,-0.4007005636256563,-1.1836861453389294,2.452016645869307,0.1698178934496409,0.24466428827712608,-0.8427941071748147,-0.05413831981279846,0.6454164794914127,1.3780765416953078,0.7460041320543394,0.7208426436394583,0.7711752687730454,-0.07896722474974421,0.4196726296872428,-0.029298246881930074,0.3446068566314095,-0.37602212714831224,0.02041518328356238,0.21970488141706138,0.2696342378209103,0.7711752687730454,0.2696342378209103,0.39464043317762726,0.2696342378209103,-0.07896722474974421,-0.029298246881930074,4.690933619436888,0.7963560132112784,0.2696342378209103,0.39464043317762726,-0.25245210761188314,-1.1108688125620438,0.1448904124117295,0.19475606654496544,-0.3019154331601609,-1.0865677781367193,-0.326629498975423,-0.22770296967824383,-0.05413831981279846,-0.25245210761188314,0.04528843208172267,-0.10378490605866271,-1.159428089317279,0.5700786462448547,-0.6222584106680328,-0.22770296967824383,-0.4500213613594855,-0.3513317511686248,0.3196055701226996,-0.3019154331601609,0.6454164794914127,0.1698178934496409,0.7711752687730454,0.6454164794914127
3,328
Dectin 1 mediated noncanonical nf kb signaling
11
42
3.210571
0.001325
O15111,P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
126,1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,126,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,2445,772,1461,1646,1825,1648,652,1886,2553,2917,1779,3177,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,1.7344565433373995,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,-0.42536699660255867,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.47466359244301676,-0.7204036003306101,-0.1285913075228445,-1.1836861453389294,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Tnfr2 non canonical nf kb pathway
11
42
3.210571
0.001325
O15111,P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
126,1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,126,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,2445,772,1461,1646,1825,1648,652,1886,2553,2917,1779,3177,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,1.7344565433373995,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,-0.42536699660255867,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.47466359244301676,-0.7204036003306101,-0.1285913075228445,-1.1836861453389294,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Mapk6 mapk4 signaling
10
50
3.206611
0.001343
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1744,1500,380,2779,1401,3185,2205,80,1698,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,1411,772,1461,1646,1825,1578,652,1093,1203,1886,2917,1779,925,1255,360,362,1729,980,1327,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.1285913075228445,-0.029298246881930074,0.821546325140021,-0.6222584106680328,0.02041518328356238,-1.2321586172414605,-0.326629498975423,2.323431235195337,-0.10378490605866271,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.02041518328356238,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.05413831981279846,0.46976760864997624,0.1698178934496409,0.11997367421113542,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.2696342378209103,0.09506773013462308,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.24466428827712608,0.07017263198353871,0.5449858631910435,0.1448904124117295
3,328
Degradation of axin
10
37
3.20471
0.001352
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,2917,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Fceri mediated nf kb activation
11
45
3.197649
0.001386
O15111,P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
126,1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,2425,126,1500,380,2205,3279,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1084,108,1196,772,1461,1646,1825,1648,652,1886,2553,2917,1779,2115,360,362,1729,596,1175,1623
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.42536699660255867,1.7344565433373995,-0.029298246881930074,0.821546325140021,-0.326629498975423,-2.022793354150014,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.11997367421113542,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.47466359244301676,-0.7204036003306101,-0.1285913075228445,-0.2771896156285405,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295,-0.05413831981279846
3,328
Regulation of runx2 expression and activity
11
43
3.194663
0.0014
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P42224,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,371,25
828,3121,1179,396,1500,380,2205,80,768,2207,260,1239,2092,1,17,804,2489,371,2543,2389,70,25,917,1987,1084,108,772,1461,1646,1825,1648,652,1886,3025,2553,2917,1779,360,362,1729,596,494,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,0.8467461646808371,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,0.2696342378209103,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.07896722474974421,0.46976760864997624,-0.17817004308089993,-0.8427941071748147,-0.47466359244301676,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.6705487758636702,0.1448904124117295
3,328
Metabolism of polyamines
10
39
3.192017
0.001413
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2205,2674,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1768,1084,108,772,1461,1646,1825,652,1886,2917,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.326629498975423,-0.5485168178411735,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,-0.1285913075228445,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Stabilization of p53
10
40
3.175694
0.001495
P28070,Q92530,Q99436,P49720,P25788,O75832,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,108,80,17,25
828,3121,1179,396,1500,380,2379,1814,2205,80,768,2207,260,1239,2092,1,17,804,2489,583,2543,2389,70,25,1987,1084,108,772,1461,1646,1825,652,1886,2917,1779,360,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.4007005636256563,-0.15338637233363414,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,0.5449858631910435,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,0.46976760864997624,-0.17817004308089993,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Signaling by interleukins
25
114
3.1637
0.001558
P28070,O15111,P11233,P25788,O75832,P28072,P30154,P62993,P49721,P42574,Q13126,O14979,P30153,P14174,P52597,P49720,P22626,P20618,P46108,Q92530,Q99436,P08670,P60900,P42224,P09601
Processes and pathways
Reactome Pathways
msigdb_reactome
1,126,135,260,380,17,145,274,25,153,38,172,292,48,313,70,198,80,81,360,362,106,108,371,242
3055,828,3121,1179,396,2425,172,126,1500,380,578,2617,1814,2670,1139,1444,1347,1185,106,674,242,2740,1402,135,48,1294,3185,2205,1920,3279,80,601,198,3255,1697,768,2207,260,1239,998,3126,1142,2092,1,17,804,1078,292,145,839,2489,2096,2627,581,2542,371,153,1766,2543,81,523,678,2389,70,25,1642,2316,1987,1643,3186,313,1245,1084,108,1411,1196,772,1461,1646,1825,274,1044,1648,1002,1303,2108,1654,652,2449,1202,38,1203,1886,2272,2553,2894,2917,1779,3230,2115,1254,2897,2555,360,362,1478,1729,546,1675,2463,2772,596,1175,1623
-0.8916578122719323,0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.7963560132112784,-0.42536699660255867,1.3780765416953078,1.7344565433373995,-0.029298246881930074,0.821546325140021,0.5449858631910435,-0.5239113880300665,-0.15338637233363414,-0.5485168178411735,0.1448904124117295,-0.00444706101777177,0.04528843208172267,0.11997367421113542,1.9900137899010935,0.44471503673584983,1.1245621542194768,-0.5976903988876788,0.02041518328356238,1.6579497333950177,2.9164635722236136,0.07017263198353871,-1.2321586172414605,-0.326629498975423,-0.20294226174328334,-2.022793354150014,2.323431235195337,0.5199030665002794,1.2765641279126316,-1.7851473898187116,-0.10378490605866271,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,0.21970488141706138,-1.037923373617608,0.1448904124117295,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.1698178934496409,0.9981430916099898,1.6069870522177834,0.3196055701226996,-0.4500213613594855,-0.2771896156285405,-0.5239113880300665,0.5449858631910435,-0.47466359244301676,0.8467461646808371,1.5051632549185123,-0.1285913075228445,-0.47466359244301676,2.323431235195337,0.6202939974103107,0.44471503673584983,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.07896722474974421,-0.37602212714831224,-0.22770296967824383,-0.07896722474974421,-1.2321586172414605,0.9476400134093361,0.09506773013462308,0.1698178934496409,1.9644215771503513,0.02041518328356238,0.11997367421113542,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,1.0486832017281793,0.19475606654496544,-0.07896722474974421,0.21970488141706138,0.07017263198353871,-0.2771896156285405,-0.07896722474974421,0.46976760864997624,-0.42536699660255867,0.11997367421113542,3.4352196776731447,0.11997367421113542,-0.17817004308089993,-0.3513317511686248,-0.47466359244301676,-0.6958864768820794,-0.7204036003306101,-0.1285913075228445,-1.5217291046799297,-0.2771896156285405,0.09506773013462308,-0.6958864768820794,-0.47466359244301676,0.8719554923012351,0.8719554923012351,-0.00444706101777177,-0.10378490605866271,0.5951813720548296,-0.07896722474974421,-0.42536699660255867,-0.5976903988876788,0.5449858631910435,0.1448904124117295,-0.05413831981279846
3,328
Exopeptidase activity
9
32
3.163324
0.00156
P55786,Q9UIQ6,Q9NZ08,Q9HB40,Q9H3G5,P53634,P42785,P10619,O75976
Functions
GO Molecular function
msigdb_gomf
158,35,230,42,45,142,14,47,213
1031,241,213,1035,2254,47,2306,2311,2209,1079,14,2165,1355,142,158,1413,1153,1104,3202,1111,2861,1536,751,2726,45,759,42,1114,510,2902,230,35
0.19475606654496544,1.1245621542194768,1.2005227817735866,0.19475606654496544,-0.3513317511686248,2.9164635722236136,-0.37602212714831224,-0.37602212714831224,-0.326629498975423,0.1698178934496409,4.323198569429893,-0.3019154331601609,0.04528843208172267,1.6324641866784928,1.479728647315875,0.02041518328356238,0.1448904124117295,0.1698178934496409,-1.3289262534598685,0.1698178934496409,-0.6713565219046082,-0.029298246881930074,0.39464043317762726,-0.5731098445670545,3.0717987299654284,0.39464043317762726,3.175495757798002,0.1698178934496409,0.6454164794914127,-0.6958864768820794,1.1751935571078382,3.46122934532905
3,328
Pcp ce pathway
11
49
3.161967
0.001567
P28070,Q92530,Q99436,P49720,P25788,O75832,O14641,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,352,108,80,17,25
828,3121,1179,352,396,1500,380,2378,2023,1070,2536,2205,80,768,2207,260,1239,2092,1,17,804,2489,2543,2389,70,25,1987,1146,1084,108,772,1043,1461,1646,1825,1578,2498,2448,652,1886,2273,2917,1779,360,2993,362,1729,596,1175
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.8719554923012351,0.7963560132112784,-0.029298246881930074,0.821546325140021,-0.4007005636256563,-0.25245210761188314,0.1698178934496409,-0.47466359244301676,-0.326629498975423,2.323431235195337,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,2.452016645869307,3.878282602092929,-0.22770296967824383,0.1448904124117295,0.1698178934496409,1.9644215771503513,0.36961849331166047,0.19475606654496544,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.05413831981279846,-0.4500213613594855,-0.42536699660255867,0.46976760864997624,-0.17817004308089993,-0.3513317511686248,-0.7204036003306101,-0.1285913075228445,0.8719554923012351,-0.7938772325700006,0.8719554923012351,-0.10378490605866271,0.5449858631910435,0.1448904124117295
3,328
Tcf dependent signaling in response to wnt
15
62
3.154749
0.001606
P28070,Q92530,Q99436,P49720,P25788,O75832,P67870,O14641,P60900,P30153,P20618,P30154,P28072,P49721,P25054
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,329,352,108,292,80,145,17,25,399
828,3121,1179,352,396,1744,1500,380,2580,2205,2843,80,399,768,2207,260,1239,2092,1,17,804,292,145,839,1295,2489,2543,2389,1881,70,25,917,2316,1987,1084,108,772,1461,1646,1825,2790,1044,329,652,1886,2552,1888,1585,2894,2917,1779,2228,1309,2642,360,362,1729,3196,797,596,1175,2072
0.3196055701226996,-1.0135801824627193,0.11997367421113542,0.8719554923012351,0.7963560132112784,-0.1285913075228445,-0.029298246881930074,0.821546325140021,-0.49929362365311203,-0.326629498975423,-0.6713565219046082,2.323431235195337,0.7963560132112784,0.36961849331166047,-0.326629498975423,1.0739670508651682,0.09506773013462308,-0.2771896156285405,8.210394651537106,4.29697723951205,0.3446068566314095,0.9981430916099898,1.6069870522177834,0.3196055701226996,0.07017263198353871,-0.4500213613594855,-0.47466359244301676,-0.4007005636256563,-0.17817004308089993,2.452016645869307,3.878282602092929,0.2696342378209103,-0.37602212714831224,-0.22770296967824383,0.1698178934496409,1.9644215771503513,0.36961849331166047,-0.00444706101777177,-0.07896722474974421,-0.15338637233363414,-0.6222584106680328,0.19475606654496544,0.9224024553533663,0.46976760864997624,-0.17817004308089993,-0.47466359244301676,-0.17817004308089993,-0.05413831981279846,-0.6958864768820794,-0.7204036003306101,-0.1285913075228445,-0.326629498975423,0.07017263198353871,-0.5239113880300665,0.8719554923012351,0.8719554923012351,-0.10378490605866271,-1.2563728389727533,0.36961849331166047,0.5449858631910435,0.1448904124117295,-0.25245210761188314
3,328
Beta catenin independent wnt signaling
12
54
3.132287
0.001735
P28070,Q92530,Q99436,P49720,P25788,O75832,O14641,Q01970,P60900,P20618,P28072,P49721
Processes and pathways
Reactome Pathways
msigdb_reactome
1,360,362,70,260,380,352,294,108,80,17,25
828,3121,1179,352,396,1500,380,2378,2023,1070,2536,2205,80,768,2207,260,1239,2092,1,17,804,1295,2489,2543,2389,70,25,1987,1146,1084,108,772,1043,1461,1646,1825,1578,2498,2267,2448,294,652,2635,1886,2273,2917,1779,360,2993,362,1729,980,596,1175
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3,328
Regulation of mrna processing
37
91
3.123131
0.001789
P98175,Q13242,Q13247,P51116,O75525,P09651,Q07021,Q92841,Q9UMS4,P51114,Q9BWF3,Q06787,Q15007,P08621,P78362,Q8N684,Q8IYB3,Q16629,P38159,P22626,Q8IY67,P62995,Q96MU7,P52756,Q96PU8,P26368,Q15427,Q07666,P61978,P98179,Q14011,Q15287,Q9Y5S9,P17844,Q96T37,Q9UHX1,O75150
Processes and pathways
GO Biological process
msigdb_gobp
136,406,275,271,157,415,168,169,571,293,435,429,182,552,314,453,452,590,194,198,333,328,205,217,488,99,613,482,605,111,124,357,514,370,633,378,252
1497,1550,2020,2818,252,2906,157,552,1071,415,1402,1189,370,2623,625,2026,1238,198,99,1453,1982,1571,194,2390,1928,293,271,918,217,874,605,328,314,2679,136,111,2107,1885,429,168,482,1520,2223,2270,1774,406,275,1465,709,124,843,964,182,357,1657,613,1008,590,1098,2406,2918,2334,2452,2757,2642,1050,1531,1660,2715,333,452,453,850,1364,169,2124,2127,205,488,1056,3198,633,1849,435,1608,3156,1679,378,571,1334,514
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3,328