term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thin ribs | 6 | 13 | 2.653752 | 0.00796 | O95831,O75431,Q9Y619,Q9Y2D4,Q32P28,P02545 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,362,79,145,379,311 | 2734,362,437,2,311,1605,1341,1642,1942,2503,379,145,79 | -0.7182732647998294,1.0583565200530796,0.8805087750259135,4.947263399328931,1.1809557285872447,-0.10132100472084841,0.036916819296822626,-0.12123707025353514,-0.26185458923358784,-0.570571577370704,1.0230449629802814,1.934898419838436,2.530575692978956 | 3,329 |
Rna stabilization | 10 | 28 | 2.650138 | 0.008046 | Q92804,P67809,P98175,O60506,Q14103,P35637,P16989,Q08J23,Q14011,Q13148 | Processes and pathways | GO Biological process | msigdb_gobp | 68,198,291,325,433,90,147,22,123,439 | 325,2379,2132,1011,469,1600,147,90,198,291,2389,1462,22,439,1247,123,433,724,2106,2075,3275,1775,68,802,2728,941,1190,692 | 1.1460831559915547,-0.5079941104366322,-0.3636162385970527,0.250123887782108,0.8265153967127852,-0.10132100472084841,1.9187443654853857,2.361661969696948,1.6234665666051777,1.233034219287915,-0.5079941104366322,-0.022078375983966562,3.5875674867137177,0.8805087750259135,0.09554385979269663,2.110919839474487,0.8984401573767984,0.5147268428449715,-0.34317416950457963,-0.3227772068954755,-1.6593883476911249,-0.18124171644076,2.651718065289016,0.43987193147095827,-0.697025958957165,0.3264777895796106,0.13442672453612758,0.5519360920063213 | 3,329 |
Bulbar signs | 7 | 12 | 2.641468 | 0.008255 | P06753,P07602,P00846,P43243,O43681,P04062,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,37,71,488,391,84,90 | 391,71,2090,84,258,37,90,488,585,1514,1033,2125 | 0.9876055334156724,2.606454697302084,-0.34317416950457963,2.4387828133527267,1.3705830562896129,3.079474577048757,2.361661969696948,0.808450700356778,0.6627070637091839,-0.04182621575808879,0.250123887782108,-0.34317416950457963 | 3,329 |
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps | 9 | 18 | 2.640864 | 0.008269 | P11047,Q9BTY2,P07237,Q8NBJ4,O76024,Q02818,O43852,Q07065,Q86UP2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 319,106,609,173,486,87,151,192,663 | 151,486,609,1066,319,1452,1236,2589,878,87,192,1612,2023,723,1584,663,173,106 | 1.9025645408220684,0.808450700356778,0.6259248892678739,0.21171518891726354,1.1635348870399604,-0.022078375983966562,0.09554385979269663,-0.633579801148074,0.3644259519210431,2.423404607484258,1.656706107741725,-0.10132100472084841,-0.30242511290885793,0.5147268428449715,-0.08144731718816471,0.5704867554835045,1.7557699570002447,2.2683494174632868 | 3,329 |
Glycosaminoglycan metabolism | 7 | 16 | 2.639452 | 0.008304 | P07686,P54802,P08236,P06865,Q8NCH0,P16278,P15586 | Processes and pathways | Reactome Pathways | msigdb_reactome | 191,42,203,48,88,89,28 | 2167,532,876,48,191,203,457,28,89,42,265,88,3174,2989,2401,1836 | -0.3841036540358946,0.7358533885259184,0.3644259519210431,2.889869040112362,1.656706107741725,1.6068053843688597,0.8445465421230678,3.3365352957295134,2.3771322660471457,2.992386889912926,1.353493558594779,2.39257941597618,-1.2212885959722362,-0.911772113327617,-0.5079941104366322,-0.20132948448448468 | 3,329 |
Outer mitochondrial membrane protein complex | 7 | 16 | 2.62932 | 0.008556 | Q8N4H5,Q13505,Q9NS69,O75431,Q5XKP0,Q15388,Q9BUR5 | Localization | GO Cellular component | msigdb_gocc | 162,35,9,362,402,314,281 | 362,1525,1043,2486,35,314,725,648,402,1287,162,281,9,1834,492,949 | 1.0583565200530796,-0.061615792131849874,0.2309390068867304,-0.570571577370704,3.1515051189672456,1.1809557285872447,0.5147268428449715,0.5890016665615532,0.9698375183938124,0.07604207936374303,1.8375855545892803,1.3020475866709618,4.0728316680909415,-0.20132948448448468,0.808450700356778,0.3264777895796106 | 3,329 |
Organic acid transport | 14 | 44 | 2.624645 | 0.008674 | P08183,Q9H2J7,P23786,P53985,O43772,P14174,P41440,Q15041,Q9Y619,Q9Y3D6,P28288,Q9H2D1,Q96QD8,P31749 | Processes and pathways | GO Biological process | msigdb_gobp | 66,260,132,102,170,11,459,174,79,408,487,111,511,288 | 2374,2788,170,1374,1229,952,1930,593,2050,2931,1570,1233,2847,66,780,11,132,487,288,1313,459,1856,2454,102,1016,814,1018,3002,174,1613,1727,2305,541,1869,511,111,260,828,1220,2693,708,657,408,79 | -0.5079941104366322,-0.7609174191294885,1.7557699570002447,0.01729293365438732,0.09554385979269663,0.30744678607403986,-0.26185458923358784,0.6443335267862096,-0.3227772068954755,-0.868413390715352,-0.08144731718816471,0.09554385979269663,-0.8037628442848861,2.6667623059751864,0.4586406374483879,4.033205903886388,2.015285552547435,0.808450700356778,1.2676011393842441,0.056499799932090956,0.8445465421230678,-0.2214607347757375,-0.5496649089080891,2.283960358788461,0.250123887782108,0.4210662853564488,0.250123887782108,-0.9335298774233274,1.7393268960087505,-0.10132100472084841,-0.16119720617815728,-0.4458404075802983,0.7358533885259184,-0.2214607347757375,0.7722200535599743,2.2370562287908466,1.3705830562896129,0.4210662853564488,0.11500534183447479,-0.6758281295241295,0.5333495101832308,0.5890016665615532,0.9698375183938124,2.530575692978956 | 3,329 |
Peptidase activity | 32 | 116 | 2.620077 | 0.008791 | P28070,Q96K76,Q9NZ08,Q92820,Q96RU2,P07858,P28074,Q9HB40,Q92542,P49721,P10619,P42892,Q9UIQ6,Q9BYT8,P42785,Q4J6C6,Q96FZ2,Q8TCT8,Q9UJ14,O75976,Q16740,Q9H3G5,P53634,P55786,Q9BXS4,P28072,P09960,O00303,P22695,Q10713,Q5JRX3,O14773 | Functions | GO Molecular function | msigdb_gomf | 3,259,267,270,140,15,269,18,275,277,29,158,36,295,38,292,47,49,309,190,322,69,73,207,81,205,336,334,97,234,255,125 | 334,1309,125,569,794,1376,437,190,1794,713,554,1712,2617,15,336,29,2849,2482,1933,555,534,97,2135,3,205,269,3035,2420,1972,860,1603,957,1760,38,158,1852,2977,1535,277,2385,2180,2059,1576,1680,861,73,2980,207,992,356,519,3319,1424,2066,234,3042,1180,2391,2680,1812,322,292,3140,255,1817,2466,2938,2541,1286,649,3279,2634,49,1735,275,2112,270,1909,964,3118,1084,1000,423,1361,47,259,2156,140,1622,653,2946,462,1217,801,81,295,69,1742,2196,871,18,2642,757,2868,1005,3064,1629,2813,267,36,309,2341,1921,2902,987,1884 | 1.128600403817568,0.056499799932090956,2.0791412514311314,0.6810456600510115,0.43987193147095827,0.01729293365438732,0.8805087750259135,1.656706107741725,-0.20132948448448468,0.5147268428449715,0.6993494746743326,-0.16119720617815728,-0.6546795012118433,3.792393479986781,1.128600403817568,3.308276986291303,-0.8037628442848861,-0.570571577370704,-0.26185458923358784,0.6993494746743326,0.7358533885259184,2.299547646576927,-0.3636162385970527,4.700755513120214,1.6068053843688597,1.3363745627961907,-0.9772037308061117,-0.5288058395850292,-0.2821176516631388,0.38334347232626,-0.10132100472084841,0.30744678607403986,-0.18124171644076,3.0650096063498165,1.8538694542435388,-0.2214607347757375,-0.911772113327617,-0.061615792131849874,1.3020475866709618,-0.5079941104366322,-0.3841036540358946,-0.3227772068954755,-0.08144731718816471,-0.14119573105890607,0.38334347232626,2.576169488318419,-0.911772113327617,1.6068053843688597,0.2692700201272898,1.0759646908980987,0.7540537998227098,-3.6794446794702353,-0.0023720624187788543,-0.3227772068954755,1.4725073343753479,-0.9772037308061117,0.13442672453612758,-0.5079941104366322,-0.6758281295241295,-0.20132948448448468,1.1635348870399604,1.233034219287915,-1.1540560850036303,1.3876431774355307,-0.20132948448448468,-0.5496649089080891,-0.868413390715352,-0.5915261061872295,0.07604207936374303,0.5890016665615532,-1.6830633641044765,-0.6546795012118433,2.8751418901299015,-0.16119720617815728,1.3192259465409601,-0.34317416950457963,1.3363745627961907,-0.2416356936301747,0.30744678607403986,-1.1095143380892818,0.21171518891726354,0.2692700201272898,0.9163385785184769,0.036916819296822626,2.9045756177690114,1.3705830562896129,-0.3636162385970527,1.9510268020575328,-0.10132100472084841,0.5890016665615532,-0.868413390715352,0.8445465421230678,0.11500534183447479,0.43987193147095827,2.5153331882484165,1.233034219287915,2.6366521005850774,-0.16119720617815728,-0.3841036540358946,0.38334347232626,3.6425673029511563,-0.6546795012118433,0.49606792158741364,-0.8037628442848861,0.2692700201272898,-0.9991204363631442,-0.10132100472084841,-0.7609174191294885,1.353493558594779,3.1515051189672456,1.1983458113760501,-0.4665116478934158,-0.2416356936301747,-0.8252617481736726,0.28837759100545446,-0.2214607347757375 | 3,329 |
Juvenile onset | 13 | 42 | 2.619102 | 0.008816 | P16278,P07196,Q03252,P06753,Q9NQ11,P57740,P54802,P06280,Q13510,Q9NR77,O15118,P02545,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 89,130,230,258,199,233,42,76,82,116,183,311,125 | 125,183,1092,3032,311,1450,76,258,130,89,2792,879,2706,880,2934,459,1717,1855,2058,369,1341,640,42,233,230,978,2265,82,1985,583,2227,3046,1774,771,2514,2120,199,1006,116,3301,1837,2814 | 2.0791412514311314,1.6898359456674157,0.19245224389382748,-0.9772037308061117,1.1809557285872447,-0.022078375983966562,2.5457958590928893,1.3705830562896129,2.0312870262355047,2.3771322660471457,-0.7609174191294885,0.3644259519210431,-0.697025958957165,0.3644259519210431,-0.868413390715352,0.8445465421230678,-0.16119720617815728,-0.2214607347757375,-0.3227772068954755,1.0407166564438557,0.036916819296822626,0.5890016665615532,2.992386889912926,1.4893937050735215,1.5062515283479845,0.28837759100545446,-0.4252154935543211,2.4847808474675808,-0.2821176516631388,0.6627070637091839,-0.40463665770934043,-0.9772037308061117,-0.18124171644076,0.4773725767590705,-0.570571577370704,-0.34317416950457963,1.6234665666051777,0.2692700201272898,2.1899368722600734,-2.170702373003225,-0.20132948448448468,-0.7609174191294885 | 3,329 |
Glycosyl compound catabolic process | 7 | 11 | 2.616913 | 0.008873 | P04066,Q9BTY2,Q9NUJ1,P06280,Q13126,P08236,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 40,106,75,76,77,203,84 | 2554,268,84,40,76,203,3255,77,106,426,75 | -0.6125287588483042,1.3363745627961907,2.4387828133527267,3.0069513662975234,2.5457958590928893,1.6068053843688597,-1.4722614175831443,2.530575692978956,2.2683494174632868,0.9163385785184769,2.560993764910525 | 3,329 |
K Homology domain, type 1 superfamily [IPR036612] | 11 | 28 | 2.608803 | 0.009086 | P51116,Q96PU8,P61978,Q07666,Q92945,Q9Y2W6,O75525,P51114,Q96I24,Q06787,Q96AE4 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 355,134,229,460,524,41,139,345,602,598,419 | 1567,2410,139,345,355,1240,229,2223,598,460,1943,741,2072,1284,995,2154,1865,2110,1358,524,419,602,134,1697,2280,1190,41,674 | -0.08144731718816471,-0.5288058395850292,1.9510268020575328,1.1110864980035515,1.0759646908980987,0.09554385979269663,1.5062515283479845,-0.40463665770934043,0.6443335267862096,0.8445465421230678,-0.26185458923358784,0.49606792158741364,-0.3227772068954755,0.07604207936374303,0.2692700201272898,-0.3636162385970527,-0.2214607347757375,-0.34317416950457963,0.036916819296822626,0.7540537998227098,0.952037115657918,0.6443335267862096,1.9832069398504246,-0.14119573105890607,-0.4252154935543211,0.13442672453612758,3.0069513662975234,0.5704867554835045 | 3,329 |
Inner mitochondrial membrane protein complex | 36 | 79 | 2.608258 | 0.0091 | Q99595,O75380,Q5HYI7,Q9P0J0,O14949,P47985,O75489,O96000,P20674,P56385,Q5XKP0,Q96CU9,Q9BUR5,P06576,O95168,Q13505,O14548,P14406,O75947,P13073,O43676,O14925,P00846,Q9Y6M9,Q16891,Q53H12,Q9UDW1,P22695,Q9NX63,O75431,O75438,O75964,P35232,P00403,Q86Y39,Q9Y5J7 | Localization | GO Cellular component | msigdb_gocc | 1,382,648,792,136,384,638,393,517,642,402,280,281,795,409,35,793,169,677,680,189,449,71,202,725,214,221,97,492,362,485,112,738,499,380,252 | 1660,2045,793,449,136,189,2906,807,382,362,485,638,677,112,1335,409,1847,1232,393,499,71,2090,795,1415,1753,1095,2417,680,169,1571,1796,2452,517,2012,97,902,2704,3166,1382,1671,738,903,2486,384,2668,2915,1279,1457,2531,642,1315,35,1318,1946,725,887,214,648,402,380,1083,1507,280,1648,1,1590,1650,281,1479,1834,1058,492,792,221,2695,987,949,252,202 | -0.14119573105890607,-0.3227772068954755,0.43987193147095827,0.86254428557863,1.9671296097282782,1.656706107741725,-0.8468118326324626,0.4210662853564488,1.0053413016312243,1.0583565200530796,0.808450700356778,0.5890016665615532,0.5519360920063213,2.2213738074871006,0.036916819296822626,0.952037115657918,-0.2214607347757375,0.09554385979269663,0.9876055334156724,0.7903523030093713,2.606454697302084,-0.34317416950457963,0.43987193147095827,-0.0023720624187788543,-0.18124171644076,0.19245224389382748,-0.5288058395850292,0.5519360920063213,1.7721862323247783,-0.08144731718816471,-0.20132948448448468,-0.5496649089080891,0.7540537998227098,-0.30242511290885793,2.299547646576927,0.34547078437245365,-0.697025958957165,-1.2212885959722362,0.01729293365438732,-0.14119573105890607,0.49606792158741364,0.34547078437245365,-0.570571577370704,1.0053413016312243,-0.6758281295241295,-0.8468118326324626,0.07604207936374303,-0.022078375983966562,-0.5915261061872295,0.5890016665615532,0.056499799932090956,3.1515051189672456,0.056499799932090956,-0.26185458923358784,0.5147268428449715,0.3644259519210431,1.590116447393389,0.5890016665615532,0.9698375183938124,1.0230449629802814,0.21171518891726354,-0.04182621575808879,1.3020475866709618,-0.12123707025353514,5.020181225676923,-0.08144731718816471,-0.12123707025353514,1.3020475866709618,-0.022078375983966562,-0.20132948448448468,0.2309390068867304,0.808450700356778,0.4586406374483879,1.539881993567282,-0.6758281295241295,0.28837759100545446,0.3264777895796106,1.4046740427964144,1.6234665666051777 | 3,329 |
Translocation | 15 | 46 | 2.590316 | 0.009589 | Q99595,O75381,O14925,Q8NFH4,O60220,Q9NS69,P57740,P41208,Q15629,Q9Y5J9,O43615,Q8TD16,O15504,P37198,Q9Y5J7 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 1,253,449,331,227,9,233,326,209,272,360,177,375,378,252 | 2949,449,375,360,227,253,2519,594,1675,378,326,2423,1895,1680,233,3169,1683,1387,1209,209,887,2718,727,650,1023,3262,331,1293,177,2031,1774,2965,461,1995,1028,1,619,3143,1872,1404,9,1371,1593,1747,252,272 | -0.890066718141344,0.86254428557863,1.0230449629802814,1.0583565200530796,1.5062515283479845,1.3876431774355307,-0.5915261061872295,0.6443335267862096,-0.14119573105890607,1.0230449629802814,1.1460831559915547,-0.5288058395850292,-0.2416356936301747,-0.14119573105890607,1.4893937050735215,-1.2212885959722362,-0.14119573105890607,0.01729293365438732,0.11500534183447479,1.6068053843688597,0.3644259519210431,-0.697025958957165,0.5147268428449715,0.5890016665615532,0.250123887782108,-1.5186699256222254,1.1460831559915547,0.07604207936374303,1.722856944340898,-0.30242511290885793,-0.18124171644076,-0.890066718141344,0.8445465421230678,-0.2821176516631388,0.250123887782108,5.020181225676923,0.6259248892678739,-1.1540560850036303,-0.2214607347757375,0.01729293365438732,4.0728316680909415,0.036916819296822626,-0.08144731718816471,-0.16119720617815728,1.4046740427964144,1.3363745627961907 | 3,329 |
Cis golgi network | 9 | 15 | 2.587382 | 0.009671 | O43731,P49755,Q08379,P24390,P30533,Q9NPR9,Q96JB2,O00461,Q8TBA6 | Localization | GO Cellular component | msigdb_gocc | 65,610,501,215,559,24,441,124,665 | 124,65,215,559,610,501,862,1815,665,1552,1908,441,704,24,2284 | 2.095042906490493,2.6667623059751864,1.5733996445856413,0.6993494746743326,0.6259248892678739,0.7903523030093713,0.38334347232626,-0.20132948448448468,0.5704867554835045,-0.061615792131849874,-0.2416356936301747,0.8805087750259135,0.5333495101832308,3.55996227274714,-0.4252154935543211 | 3,329 |
Intrinsic apoptotic signaling pathway in response to dna damage | 7 | 26 | 2.577967 | 0.009938 | P46379,Q96K76,P61978,Q9Y3B8,P14174,Q96RU2,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 98,259,229,201,11,140,94 | 1844,2653,1889,2133,94,343,1338,11,1097,1533,1760,98,3071,2490,229,2148,1543,932,661,1022,1002,259,2862,140,3027,201 | -0.2214607347757375,-0.6758281295241295,-0.2416356936301747,-0.3636162385970527,2.3151113665623173,1.1110864980035515,0.036916819296822626,4.033205903886388,0.19245224389382748,-0.061615792131849874,-0.18124171644076,2.299547646576927,-1.0210907434410021,-0.570571577370704,1.5062515283479845,-0.3636162385970527,-0.061615792131849874,0.3264777895796106,0.5704867554835045,0.250123887782108,0.2692700201272898,1.3705830562896129,-0.8037628442848861,1.9510268020575328,-0.9553403143439382,1.6234665666051777 | 3,329 |
Endoplasmic reticulum lumen | 28 | 63 | 2.552266 | 0.010702 | Q9NZ08,P78536,O43681,O43852,P13674,O15460,Q86UP2,O75718,Q8NBJ4,P30533,Q8IXB1,Q9NWM8,O95881,O00584,P11047,O60568,Q07065,Q15293,P53634,Q14257,Q02818,P10909,Q9BTY2,P07237,O76024,Q96AY3,Q32P28,Q9Y680 | Localization | GO Cellular component | msigdb_gocc | 267,519,391,151,284,531,663,161,173,559,440,188,438,62,319,310,192,723,73,80,87,343,106,609,486,629,379,257 | 62,2005,531,391,151,310,161,486,438,609,1066,2848,343,319,1713,284,1452,1236,2589,878,2559,3197,1799,1012,2136,782,1972,559,1605,73,2670,519,87,192,1612,80,721,1150,2023,723,379,1584,907,663,440,173,1619,1469,1188,629,1399,911,1871,106,1221,188,2694,2898,267,3120,2839,2043,257 | 2.696785914647319,-0.30242511290885793,0.7358533885259184,0.9876055334156724,1.9025645408220684,1.1809557285872447,1.8375855545892803,0.808450700356778,0.8805087750259135,0.6259248892678739,0.21171518891726354,-0.8037628442848861,1.1110864980035515,1.1635348870399604,-0.16119720617815728,1.2848393592155545,-0.022078375983966562,0.09554385979269663,-0.633579801148074,0.3644259519210431,-0.6125287588483042,-1.2890331559905834,-0.20132948448448468,0.250123887782108,-0.3636162385970527,0.4586406374483879,-0.2821176516631388,0.6993494746743326,-0.10132100472084841,2.576169488318419,-0.6758281295241295,0.7540537998227098,2.423404607484258,1.656706107741725,-0.10132100472084841,2.5153331882484165,0.5147268428449715,0.15380820539298756,-0.30242511290885793,0.5147268428449715,1.0230449629802814,-0.08144731718816471,0.34547078437245365,0.5704867554835045,0.8805087750259135,1.7557699570002447,-0.10132100472084841,-0.022078375983966562,0.13442672453612758,0.6074809899769386,0.01729293365438732,0.34547078437245365,-0.2214607347757375,2.2683494174632868,0.11500534183447479,1.6732846853550996,-0.6758281295241295,-0.8252617481736726,1.353493558594779,-1.1095143380892818,-0.7823148305441647,-0.30242511290885793,1.3876431774355307 | 3,329 |
Amyloid beta binding | 10 | 14 | 2.546019 | 0.010896 | Q5SW96,O00264,Q9UHV9,P61758,O60925,Q07954,Q8WTV0,P30533,O15212,P10909 | Functions | GO Molecular function | msigdb_gomf | 799,324,436,716,335,244,86,559,317,343 | 324,317,335,833,343,559,716,244,1724,799,86,1130,1369,436 | 1.1460831559915547,1.1635348870399604,1.128600403817568,0.40222352433548514,1.1110864980035515,0.6993494746743326,0.5147268428449715,1.4216757723522286,-0.16119720617815728,0.43987193147095827,2.4387828133527267,0.17314998036516657,0.036916819296822626,0.8984401573767984 | 3,329 |
Protein transmembrane transport | 7 | 24 | 2.537394 | 0.011168 | Q99595,O95831,O75381,Q9NS69,Q15629,O43615,Q15388 | Processes and pathways | GO Biological process | msigdb_gobp | 1,2,253,9,209,360,314 | 449,360,1093,253,1525,2,1043,2874,610,1147,3169,2773,1683,932,314,209,887,3289,1023,1995,1,1479,9,945 | 0.86254428557863,1.0583565200530796,0.19245224389382748,1.3876431774355307,-0.061615792131849874,4.947263399328931,0.2309390068867304,-0.8252617481736726,0.6259248892678739,0.15380820539298756,-1.2212885959722362,-0.7395703247870165,-0.14119573105890607,0.3264777895796106,1.1809557285872447,1.6068053843688597,0.3644259519210431,-1.7544772036562493,0.250123887782108,-0.2821176516631388,5.020181225676923,-0.022078375983966562,4.0728316680909415,0.3264777895796106 | 3,329 |
SLC superfamily of solute carriers | 19 | 40 | 2.536046 | 0.011211 | Q9H2J7,Q9UJS0,P12235,P08195,O43772,Q70HW3,Q9UBX3,Q6NT16,Q8IXU6,P41440,Q9Y619,Q9H2V7,Q9HC07,O95563,Q9BSK2,Q9Y6C9,P53985,Q9H2D1,Q96QD8 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 260,657,763,780,170,46,708,67,330,459,79,587,220,593,100,359,102,111,511 | 170,1374,952,1064,593,2210,780,763,2417,459,2454,102,1016,2354,1018,1727,3227,67,863,2305,46,330,890,3174,1509,1869,511,100,2514,111,260,587,828,1220,220,1033,708,657,79,359 | 1.7557699570002447,0.01729293365438732,0.30744678607403986,0.21171518891726354,0.6443335267862096,-0.40463665770934043,0.4586406374483879,0.4773725767590705,-0.5288058395850292,0.8445465421230678,-0.5496649089080891,2.283960358788461,0.250123887782108,-0.48722946472103856,0.250123887782108,-0.16119720617815728,-1.3572992144054614,2.6667623059751864,0.38334347232626,-0.4458404075802983,2.9045756177690114,1.1460831559915547,0.3644259519210431,-1.2212885959722362,-0.04182621575808879,-0.2214607347757375,0.7722200535599743,2.299547646576927,-0.570571577370704,2.2370562287908466,1.3705830562896129,0.6627070637091839,0.4210662853564488,0.11500534183447479,1.539881993567282,0.250123887782108,0.5333495101832308,0.5890016665615532,2.530575692978956,1.0759646908980987 | 3,329 |
Inorganic anion transport | 8 | 22 | 2.530921 | 0.011376 | P45880,P08183,O43681,Q9H813,P21796,P30536,Q9C0H2,Q9UHG3 | Processes and pathways | GO Biological process | msigdb_gobp | 34,66,391,251,16,85,59,159 | 2950,2788,391,66,1068,16,85,34,1101,641,1016,2354,1018,3227,476,59,967,251,708,159,1060,2903 | -0.890066718141344,-0.7609174191294885,0.9876055334156724,2.6667623059751864,0.21171518891726354,3.724546859902729,2.4387828133527267,3.1801811755749765,0.19245224389382748,0.5890016665615532,0.250123887782108,-0.48722946472103856,0.250123887782108,-1.3572992144054614,0.8265153967127852,2.7416602578229923,0.30744678607403986,1.4046740427964144,0.5333495101832308,1.8538694542435388,0.2309390068867304,-0.8252617481736726 | 3,329 |
Abnormal lower limb bone morphology | 55 | 182 | 2.529383 | 0.011426 | O95831,Q96A33,Q7LGA3,O43909,P00813,O00192,Q9Y2D4,Q96HY6,Q08J23,Q9NX62,O00754,Q15392,Q9H9E3,O43505,P31749,Q6NUQ1,O75718,P07602,Q9Y487,P04066,P98175,O96028,Q02224,Q7RTS9,Q15058,P13073,O14936,P02545,O60568,O75844,Q13555,P21964,O00116,P06280,Q9Y619,P08236,Q8WXW3,Q9H9S5,Q13510,P04062,P15260,P16278,Q06787,Q15125,O75648,Q03252,Q9Y4W2,Q10713,O75431,Q96PZ0,Q96AY3,Q14683,Q32P28,Q9UHX1,O95613 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,525,265,392,268,515,145,405,22,672,150,155,670,532,288,662,161,37,166,40,291,43,562,306,434,680,552,311,310,437,700,320,72,76,79,203,600,607,82,84,204,89,598,218,341,230,495,234,362,114,629,626,379,381,622 | 3162,72,515,3163,3122,2477,150,2734,552,734,1168,2204,532,392,1375,2479,1228,310,2290,2250,3014,1449,362,341,161,1412,437,1636,1064,2051,622,2,2653,2816,43,268,311,84,40,2133,76,37,3112,203,877,680,204,89,1380,3052,2055,2257,2702,320,2559,697,2523,2955,2136,288,811,2706,1533,2486,1973,2527,1014,1071,2957,2384,1048,1147,2098,2879,1148,2742,1016,2530,2773,291,562,1346,230,598,2103,22,815,234,3072,2538,2019,82,700,2500,1389,2677,626,1250,2431,2681,434,218,155,1104,2503,379,3022,817,1584,2718,1080,1547,819,662,3291,2885,265,306,3216,2507,2985,1288,1110,1470,3210,2920,600,1294,1909,1646,3118,1084,1214,525,629,405,2989,114,1157,2578,2689,1028,2275,2438,2119,1592,3145,1876,2239,2607,1696,2405,3029,1300,828,670,607,3090,1368,2201,1629,3119,2000,672,1481,2783,1033,1630,381,1631,1138,2125,1920,898,145,2647,166,2517,495,1090,3101,79 | -1.2212885959722362,2.576169488318419,0.7540537998227098,-1.2212885959722362,-1.1317574422993255,-0.570571577370704,1.9025645408220684,-0.7182732647998294,0.6993494746743326,0.49606792158741364,0.13442672453612758,-0.40463665770934043,0.7358533885259184,0.9876055334156724,0.01729293365438732,-0.570571577370704,0.09554385979269663,1.1809557285872447,-0.4458404075802983,-0.4252154935543211,-0.9553403143439382,-0.022078375983966562,1.0583565200530796,1.1110864980035515,1.8375855545892803,-0.0023720624187788543,0.8805087750259135,-0.12123707025353514,0.21171518891726354,-0.3227772068954755,0.6074809899769386,4.947263399328931,-0.6758281295241295,-0.7823148305441647,2.9778023149588617,1.3363745627961907,1.1809557285872447,2.4387828133527267,3.0069513662975234,-0.3636162385970527,2.5457958590928893,3.079474577048757,-1.1095143380892818,1.6068053843688597,0.3644259519210431,0.5519360920063213,1.6068053843688597,2.3771322660471457,0.01729293365438732,-0.9991204363631442,-0.3227772068954755,-0.4252154935543211,-0.697025958957165,1.1635348870399604,-0.6125287588483042,0.5333495101832308,-0.5915261061872295,-0.890066718141344,-0.3636162385970527,1.2676011393842441,0.4210662853564488,-0.697025958957165,-0.061615792131849874,-0.570571577370704,-0.2821176516631388,-0.5915261061872295,0.250123887782108,0.21171518891726354,-0.890066718141344,-0.5079941104366322,0.2309390068867304,0.15380820539298756,-0.34317416950457963,-0.8252617481736726,0.15380820539298756,-0.7182732647998294,0.250123887782108,-0.5915261061872295,-0.7395703247870165,1.233034219287915,0.6993494746743326,0.036916819296822626,1.5062515283479845,0.6443335267862096,-0.34317416950457963,3.5875674867137177,0.4210662853564488,1.4725073343753479,-1.0210907434410021,-0.5915261061872295,-0.30242511290885793,2.4847808474675808,0.5333495101832308,-0.570571577370704,0.01729293365438732,-0.6758281295241295,0.6074809899769386,0.09554385979269663,-0.5288058395850292,-0.6758281295241295,0.8984401573767984,1.5566548641470208,1.8863588470765684,0.19245224389382748,-0.570571577370704,1.0230449629802814,-0.9553403143439382,0.4210662853564488,-0.08144731718816471,-0.697025958957165,0.21171518891726354,-0.061615792131849874,0.4210662853564488,0.5704867554835045,-1.8990934234313346,-0.8252617481736726,1.353493558594779,1.1983458113760501,-1.3344853226815454,-0.570571577370704,-0.911772113327617,0.07604207936374303,0.19245224389382748,-0.022078375983966562,-1.3117300899642415,-0.8468118326324626,0.6443335267862096,0.07604207936374303,-0.2416356936301747,-0.12123707025353514,-1.1095143380892818,0.21171518891726354,0.11500534183447479,0.7540537998227098,0.6074809899769386,0.9698375183938124,-0.911772113327617,2.205667384725738,0.15380820539298756,-0.6125287588483042,-0.6758281295241295,0.250123887782108,-0.4252154935543211,-0.5288058395850292,-0.34317416950457963,-0.08144731718816471,-1.1540560850036303,-0.2214607347757375,-0.40463665770934043,-0.633579801148074,-0.14119573105890607,-0.5079941104366322,-0.9553403143439382,0.07604207936374303,0.4210662853564488,0.5704867554835045,0.6443335267862096,-1.043114967374901,0.036916819296822626,-0.3841036540358946,-0.10132100472084841,-1.1095143380892818,-0.2821176516631388,0.5704867554835045,-0.022078375983966562,-0.7395703247870165,0.250123887782108,-0.10132100472084841,1.0230449629802814,-0.10132100472084841,0.17314998036516657,-0.34317416950457963,-0.2416356936301747,0.3644259519210431,1.934898419838436,-0.6546795012118433,1.80493884277799,-0.570571577370704,0.808450700356778,0.21171518891726354,-1.0651934264465188,2.530575692978956 | 3,329 |
Carboxylic acid transport | 12 | 33 | 2.51544 | 0.011888 | Q9H2J7,Q9UJS0,P07602,P53985,P14174,P41440,Q15041,Q9Y619,P28288,Q9H2D1,Q96QD8,O95563 | Processes and pathways | GO Biological process | msigdb_gobp | 260,657,37,102,11,459,174,79,487,111,511,593 | 2374,2788,1229,952,1930,593,1570,1233,37,780,11,487,459,2454,102,1016,1018,3002,174,1613,1727,2305,1869,511,111,260,828,1220,2693,1033,708,657,79 | -0.5079941104366322,-0.7609174191294885,0.09554385979269663,0.30744678607403986,-0.26185458923358784,0.6443335267862096,-0.08144731718816471,0.09554385979269663,3.079474577048757,0.4586406374483879,4.033205903886388,0.808450700356778,0.8445465421230678,-0.5496649089080891,2.283960358788461,0.250123887782108,0.250123887782108,-0.9335298774233274,1.7393268960087505,-0.10132100472084841,-0.16119720617815728,-0.4458404075802983,-0.2214607347757375,0.7722200535599743,2.2370562287908466,1.3705830562896129,0.4210662853564488,0.11500534183447479,-0.6758281295241295,0.250123887782108,0.5333495101832308,0.5890016665615532,2.530575692978956 | 3,329 |
Signaling | 6 | 17 | 2.51406 | 0.011935 | P43490,O14641,Q96PC5,O00264,O15173,Q8WUJ1 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 412,448,301,324,121,30 | 324,448,121,1140,1146,412,2099,1543,932,538,1584,799,1255,30,301,1029,1836 | 1.1460831559915547,0.86254428557863,2.110919839474487,0.15380820539298756,0.15380820539298756,0.952037115657918,-0.34317416950457963,-0.061615792131849874,0.3264777895796106,0.7358533885259184,-0.08144731718816471,0.43987193147095827,0.09554385979269663,3.308276986291303,1.215705265275244,0.250123887782108,-0.20132948448448468 | 3,329 |
calmodulin-related | 6 | 14 | 2.508859 | 0.012112 | P41208,Q14257,Q02818,O43852,P80303,P0DP25 | Functions | Panther Protein class | panther_protein_class | 326,80,87,151,26,312 | 151,312,1144,3018,326,1124,26,87,80,723,1083,576,1650,406 | 1.9025645408220684,1.1809557285872447,0.15380820539298756,-0.9553403143439382,1.1460831559915547,0.17314998036516657,3.364719210270262,2.423404607484258,2.5153331882484165,0.5147268428449715,0.21171518891726354,0.6810456600510115,-0.12123707025353514,0.9698375183938124 | 3,329 |
Aminoglycan metabolic process | 8 | 17 | 2.505653 | 0.012223 | P07686,P04066,P54802,P08236,P06865,Q8NCH0,P16278,P15586 | Processes and pathways | GO Biological process | msigdb_gobp | 191,40,42,203,48,88,89,28 | 532,2736,3238,40,48,191,203,28,89,3233,42,3001,265,88,2989,2694,672 | 0.7358533885259184,-0.7182732647998294,-1.4031044336556613,3.0069513662975234,2.889869040112362,1.656706107741725,1.6068053843688597,3.3365352957295134,2.3771322660471457,-1.3801721289355482,2.992386889912926,-0.9335298774233274,1.353493558594779,2.39257941597618,-0.911772113327617,-0.6758281295241295,0.5704867554835045 | 3,329 |
Calmodulin | 8 | 16 | 2.482523 | 0.013046 | P41208,Q14257,Q9BRK5,Q02818,O43852,P80303,P0DP25,Q99584 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 326,80,406,87,151,26,312,576 | 151,312,3018,326,571,1124,26,87,80,723,2231,1083,1022,576,1650,406 | 1.9025645408220684,1.1809557285872447,-0.9553403143439382,1.1460831559915547,0.6810456600510115,0.17314998036516657,3.364719210270262,2.423404607484258,2.5153331882484165,0.5147268428449715,-0.40463665770934043,0.21171518891726354,0.250123887782108,0.6810456600510115,-0.12123707025353514,0.9698375183938124 | 3,329 |
Intracellular calcium-sensing protein | 8 | 16 | 2.482523 | 0.013046 | P41208,Q14257,Q9BRK5,Q02818,O43852,P80303,P0DP25,Q99584 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 326,80,406,87,151,26,312,576 | 151,312,3018,326,571,1124,26,87,80,723,2231,1083,1022,576,1650,406 | 1.9025645408220684,1.1809557285872447,-0.9553403143439382,1.1460831559915547,0.6810456600510115,0.17314998036516657,3.364719210270262,2.423404607484258,2.5153331882484165,0.5147268428449715,-0.40463665770934043,0.21171518891726354,0.250123887782108,0.6810456600510115,-0.12123707025353514,0.9698375183938124 | 3,329 |
Secretory vesicle | 68 | 266 | 2.480268 | 0.013128 | Q99536,Q9UQB8,P42892,Q86Y82,P14174,Q92820,P61916,P07858,O43681,Q92542,O00754,P50897,P15586,P07437,P10619,P78371,P30519,Q8NBX0,P45880,P20618,O00231,P07602,P42785,O00560,P04066,O43760,Q9Y487,P10321,P11279,Q13813,Q96JJ7,P06865,P27105,O43707,P17900,Q9BRF8,P35613,P0DP25,Q07065,O00584,P13473,P07686,O95721,Q9Y2Q5,P53634,P06280,O00264,P08236,P15291,P09960,Q13510,Q9NUQ9,P16278,P01889,O43242,P10909,Q9H7Z7,Q9BTY2,O43752,Q08380,P10253,O76024,O15400,Q9NV96,Q9NTK5,Q93050,P11717,Q9UEU0 | Localization | GO Cellular component | msigdb_gocc | 527,135,158,397,11,270,142,15,391,275,150,27,28,533,29,154,32,33,34,534,543,37,38,544,40,545,166,298,299,563,424,48,54,553,56,442,313,312,192,62,570,191,318,592,73,76,324,203,457,336,82,349,89,467,340,343,358,106,104,105,109,486,368,505,504,120,377,390 | 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| 3,329 |
Negative regulation of mrna catabolic process | 13 | 26 | 2.471002 | 0.013474 | P07910,Q92804,Q9Y2W1,P67809,P98175,O60506,Q14103,P35637,P16989,Q06787,Q13148,Q14011,Q99729 | Processes and pathways | GO Biological process | msigdb_gobp | 469,68,692,198,291,325,433,90,147,598,439,123,286 | 2844,325,2132,469,1600,147,90,198,291,2389,598,1462,439,1247,123,433,724,2106,2075,3275,1775,68,286,802,1190,692 | -0.8037628442848861,1.1460831559915547,-0.3636162385970527,0.8265153967127852,-0.10132100472084841,1.9187443654853857,2.361661969696948,1.6234665666051777,1.233034219287915,-0.5079941104366322,0.6443335267862096,-0.022078375983966562,0.8805087750259135,0.09554385979269663,2.110919839474487,0.8984401573767984,0.5147268428449715,-0.34317416950457963,-0.3227772068954755,-1.6593883476911249,-0.18124171644076,2.651718065289016,1.2848393592155545,0.43987193147095827,0.13442672453612758,0.5519360920063213 | 3,329 |
Pain | 52 | 192 | 2.464403 | 0.013724 | P28070,P23786,P14174,Q15056,Q9NZ08,O00192,Q01082,Q96HY6,Q6UN15,Q14108,Q9H6K4,Q15800,O15460,P42892,P31749,P20700,P09651,P07602,P22626,Q8WXH0,Q70HW3,Q8IUX1,O43707,O14936,P02545,Q13148,P48735,O75844,P07686,P21964,Q92804,Q0IIM8,P00846,Q8NFH4,Q15165,Q14566,P06280,Q9H9S5,Q13510,P04062,Q7LG56,P35637,Q969G3,P01889,Q03252,P57740,Q01844,P43243,O95140,P50402,Q9NR77,Q07954 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 3,132,11,521,267,515,520,405,403,23,282,417,531,158,288,287,410,37,167,565,46,307,553,552,311,439,61,437,191,320,68,451,71,331,74,583,76,607,82,84,219,90,474,467,230,233,237,488,235,369,116,244 | 2872,515,1706,2734,552,637,1196,531,553,2205,1038,1334,1169,1888,437,856,235,3031,2653,3032,3149,71,833,467,311,84,3231,2133,76,901,37,191,2555,2700,2414,3068,410,877,2737,3309,1337,763,11,1452,3052,2589,2851,3233,287,2012,320,2295,3180,167,3270,132,697,1799,3,1277,990,1382,2664,288,1417,2139,90,860,2178,1533,2934,2913,2527,928,158,488,1851,1071,61,2978,1854,2708,2424,369,1341,1456,785,2959,3071,3168,1179,2742,2529,1681,2263,2530,233,1607,2773,2299,520,1281,237,1018,230,2627,3155,2459,598,2429,244,451,1209,1857,1180,439,1858,1580,625,82,882,2574,23,883,2713,583,1150,1250,1900,1581,521,74,1987,417,3021,3058,799,1766,2823,1504,403,3261,46,219,3128,307,2468,650,3184,331,2543,1774,2891,1187,565,2965,1294,68,1909,474,1556,405,2892,2310,1871,1366,1872,1592,2405,282,2160,607,2581,116,1629,2000,267,1033,2315,3120,3281,945,2991,2548,946,1439,2839,2901,2644,2316,3050,1409 | -0.8252617481736726,0.7540537998227098,-0.16119720617815728,-0.7182732647998294,0.6993494746743326,0.5890016665615532,0.11500534183447479,0.7358533885259184,0.6993494746743326,-0.40463665770934043,0.2309390068867304,0.036916819296822626,0.13442672453612758,-0.2416356936301747,0.8805087750259135,0.38334347232626,1.4555923000904791,-0.9772037308061117,-0.6758281295241295,-0.9772037308061117,-1.1764105997956595,2.606454697302084,0.40222352433548514,0.8265153967127852,1.1809557285872447,2.4387828133527267,-1.3801721289355482,-0.3636162385970527,2.5457958590928893,0.34547078437245365,3.079474577048757,1.656706107741725,-0.6125287588483042,-0.697025958957165,-0.5288058395850292,-1.0210907434410021,0.952037115657918,0.3644259519210431,-0.7182732647998294,-2.4512593506266778,0.036916819296822626,0.4773725767590705,4.033205903886388,-0.022078375983966562,-0.9991204363631442,-0.633579801148074,-0.8037628442848861,-1.3801721289355482,1.2676011393842441,-0.30242511290885793,1.1635348870399604,-0.4458404075802983,-1.2438127606249867,1.788575826344145,-1.5653251277560118,2.015285552547435,0.5333495101832308,-0.20132948448448468,4.700755513120214,0.07604207936374303,0.2692700201272898,0.01729293365438732,-0.6758281295241295,1.2676011393842441,-0.0023720624187788543,-0.3636162385970527,2.361661969696948,0.38334347232626,-0.3841036540358946,-0.061615792131849874,-0.868413390715352,-0.8468118326324626,-0.5915261061872295,0.3264777895796106,1.8538694542435388,0.808450700356778,-0.2214607347757375,0.21171518891726354,2.711765431291945,-0.911772113327617,-0.2214607347757375,-0.697025958957165,-0.5288058395850292,1.0407166564438557,0.036916819296822626,-0.022078375983966562,0.4586406374483879,-0.890066718141344,-1.0210907434410021,-1.2212885959722362,0.13442672453612758,-0.7182732647998294,-0.5915261061872295,-0.14119573105890607,-0.4252154935543211,-0.5915261061872295,1.4893937050735215,-0.10132100472084841,-0.7395703247870165,-0.4458404075802983,0.7540537998227098,0.07604207936374303,1.4555923000904791,0.250123887782108,1.5062515283479845,-0.6546795012118433,-1.1764105997956595,-0.5496649089080891,0.6443335267862096,-0.5288058395850292,1.4216757723522286,0.86254428557863,0.11500534183447479,-0.2214607347757375,0.13442672453612758,0.8805087750259135,-0.2214607347757375,-0.08144731718816471,0.6074809899769386,2.4847808474675808,0.3644259519210431,-0.6125287588483042,3.5875674867137177,0.3644259519210431,-0.697025958957165,0.6627070637091839,0.15380820539298756,0.09554385979269663,-0.2416356936301747,-0.08144731718816471,0.7540537998227098,2.560993764910525,-0.2821176516631388,0.952037115657918,-0.9553403143439382,-0.9991204363631442,0.43987193147095827,-0.18124171644076,-0.7823148305441647,-0.04182621575808879,0.9698375183938124,-1.5186699256222254,2.9045756177690114,1.539881993567282,-1.1317574422993255,1.1983458113760501,-0.5496649089080891,0.5890016665615532,-1.2438127606249867,1.1460831559915547,-0.5915261061872295,-0.18124171644076,-0.8252617481736726,0.13442672453612758,0.6993494746743326,-0.890066718141344,0.07604207936374303,2.651718065289016,-0.2416356936301747,0.8265153967127852,-0.061615792131849874,0.9698375183938124,-0.8252617481736726,-0.4458404075802983,-0.2214607347757375,0.036916819296822626,-0.2214607347757375,-0.08144731718816471,-0.5079941104366322,1.3020475866709618,-0.3636162385970527,0.6443335267862096,-0.6125287588483042,2.1899368722600734,-0.10132100472084841,-0.2821176516631388,1.353493558594779,0.250123887782108,-0.4458404075802983,-1.1095143380892818,-1.6830633641044765,0.3264777895796106,-0.911772113327617,-0.5915261061872295,0.3264777895796106,-0.0023720624187788543,-0.7823148305441647,-0.8252617481736726,-0.6546795012118433,-0.4458404075802983,-0.9772037308061117,0.01729293365438732 | 3,329 |
Anion transport | 19 | 64 | 2.463138 | 0.013773 | Q9H2J7,P14174,O43681,P21796,Q9UHG3,P45880,P07602,Q15041,Q9C0H2,P08183,P41440,Q9Y619,P30536,Q96S66,P53985,Q14728,P28288,Q9H2D1,Q9H813 | Processes and pathways | GO Biological process | msigdb_gobp | 260,11,391,16,159,34,37,174,59,66,459,79,85,476,102,489,487,111,251 | 2950,2374,2788,391,1374,989,1229,952,1930,593,1570,2210,1233,37,66,780,1068,763,2417,11,16,487,85,459,34,1101,2454,102,641,1016,2354,1018,1496,3002,882,489,174,1613,1727,627,3227,863,2305,3174,1869,511,476,59,967,111,260,251,828,1220,1402,2693,1033,708,159,657,1060,2948,79,2903 | -0.890066718141344,-0.5079941104366322,-0.7609174191294885,0.9876055334156724,0.01729293365438732,0.2692700201272898,0.09554385979269663,0.30744678607403986,-0.26185458923358784,0.6443335267862096,-0.08144731718816471,-0.40463665770934043,0.09554385979269663,3.079474577048757,2.6667623059751864,0.4586406374483879,0.21171518891726354,0.4773725767590705,-0.5288058395850292,4.033205903886388,3.724546859902729,0.808450700356778,2.4387828133527267,0.8445465421230678,3.1801811755749765,0.19245224389382748,-0.5496649089080891,2.283960358788461,0.5890016665615532,0.250123887782108,-0.48722946472103856,0.250123887782108,-0.04182621575808879,-0.9335298774233274,0.3644259519210431,0.808450700356778,1.7393268960087505,-0.10132100472084841,-0.16119720617815728,0.6074809899769386,-1.3572992144054614,0.38334347232626,-0.4458404075802983,-1.2212885959722362,-0.2214607347757375,0.7722200535599743,0.8265153967127852,2.7416602578229923,0.30744678607403986,2.2370562287908466,1.3705830562896129,1.4046740427964144,0.4210662853564488,0.11500534183447479,0.01729293365438732,-0.6758281295241295,0.250123887782108,0.5333495101832308,1.8538694542435388,0.5890016665615532,0.2309390068867304,-0.868413390715352,2.530575692978956,-0.8252617481736726 | 3,329 |
Metalloprotease | 10 | 27 | 2.456683 | 0.014023 | O75976,Q9UIQ6,Q9BYT8,Q99797,Q9NZ08,P55786,P09960,P42892,Q5JRX3,O75844 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 190,36,295,462,267,207,336,158,255,437 | 1309,794,1376,437,190,713,336,2849,1933,158,1576,207,519,255,649,964,2156,1622,462,295,1742,1005,3064,2813,267,36,987 | 0.056499799932090956,0.43987193147095827,0.01729293365438732,0.8805087750259135,1.656706107741725,0.5147268428449715,1.128600403817568,-0.8037628442848861,-0.26185458923358784,1.8538694542435388,-0.08144731718816471,1.6068053843688597,0.7540537998227098,1.3876431774355307,0.5890016665615532,0.30744678607403986,-0.3636162385970527,-0.10132100472084841,0.8445465421230678,1.233034219287915,-0.16119720617815728,0.2692700201272898,-0.9991204363631442,-0.7609174191294885,1.353493558594779,3.1515051189672456,0.28837759100545446 | 3,329 |
Cytochrome complex assembly | 7 | 13 | 2.444826 | 0.014492 | P53701,Q9BSK2,P47985,Q6DKK2,Q9Y2R0,Q69YU5,O75880 | Processes and pathways | GO Biological process | msigdb_gobp | 164,100,384,339,179,92,465 | 1523,465,384,164,470,92,339,745,2116,771,100,2695,179 | -0.061615792131849874,0.8265153967127852,1.0053413016312243,1.8212753847092116,0.8265153967127852,2.361661969696948,1.128600403817568,0.49606792158741364,-0.34317416950457963,0.4773725767590705,2.299547646576927,-0.6758281295241295,1.722856944340898 | 3,329 |
Subcutaneous nodule | 6 | 19 | 2.444429 | 0.014508 | Q9NZ08,P06280,Q13510,P35637,P48735,P31749 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 267,76,82,90,61,288 | 856,467,76,1234,2012,697,288,1417,90,61,2978,2708,1241,2882,2459,82,316,267,2316 | 0.38334347232626,0.8265153967127852,2.5457958590928893,0.09554385979269663,-0.30242511290885793,0.5333495101832308,1.2676011393842441,-0.0023720624187788543,2.361661969696948,2.711765431291945,-0.911772113327617,-0.697025958957165,0.09554385979269663,-0.8252617481736726,-0.5496649089080891,2.4847808474675808,1.1809557285872447,1.353493558594779,-0.4458404075802983 | 3,329 |
Respirasome | 21 | 47 | 2.441395 | 0.014631 | O75380,P47985,Q9P0J0,O14949,O75489,O96000,P20674,Q96CU9,O95168,O14548,P14406,P13073,O43676,Q9Y6M9,Q6DKK2,Q9UDW1,P22695,Q7KZN9,O75438,P00403,Q86Y39 | Localization | GO Cellular component | msigdb_gocc | 382,384,792,136,638,393,517,280,409,793,169,680,189,202,339,221,97,745,485,499,380 | 1660,2045,793,136,189,2906,807,382,485,638,1335,409,1847,1232,393,499,2090,1415,1753,1095,680,169,1571,1796,2452,517,2012,97,3166,1382,1671,384,2915,1279,1315,1580,1318,1946,339,745,380,280,1058,792,221,2695,202 | -0.14119573105890607,-0.3227772068954755,0.43987193147095827,1.9671296097282782,1.656706107741725,-0.8468118326324626,0.4210662853564488,1.0053413016312243,0.808450700356778,0.5890016665615532,0.036916819296822626,0.952037115657918,-0.2214607347757375,0.09554385979269663,0.9876055334156724,0.7903523030093713,-0.34317416950457963,-0.0023720624187788543,-0.18124171644076,0.19245224389382748,0.5519360920063213,1.7721862323247783,-0.08144731718816471,-0.20132948448448468,-0.5496649089080891,0.7540537998227098,-0.30242511290885793,2.299547646576927,-1.2212885959722362,0.01729293365438732,-0.14119573105890607,1.0053413016312243,-0.8468118326324626,0.07604207936374303,0.056499799932090956,-0.08144731718816471,0.056499799932090956,-0.26185458923358784,1.128600403817568,0.49606792158741364,1.0230449629802814,1.3020475866709618,0.2309390068867304,0.4586406374483879,1.539881993567282,-0.6758281295241295,1.6234665666051777 | 3,329 |
Abnormal visual electrophysiology | 12 | 52 | 2.439316 | 0.014715 | Q04837,P07602,Q15067,P00846,O60220,O75503,O95140,Q15555,P37198,Q53H12,P50897,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 289,37,39,71,227,14,235,370,378,214,27,125 | 125,3230,2343,391,1969,1375,227,1038,14,2699,1041,1709,235,71,37,763,1339,2706,378,2527,2058,27,1575,1344,3127,289,1810,2329,1613,39,370,1252,214,2938,1353,3046,1905,1820,615,2602,1397,476,1873,1401,3145,2239,828,942,1368,1404,1033,1519 | 2.0791412514311314,-1.3801721289355482,-0.48722946472103856,0.9876055334156724,-0.2821176516631388,0.01729293365438732,1.5062515283479845,0.2309390068867304,3.9801481206823643,-0.697025958957165,0.2309390068867304,-0.16119720617815728,1.4555923000904791,2.606454697302084,3.079474577048757,0.4773725767590705,0.036916819296822626,-0.697025958957165,1.0230449629802814,-0.5915261061872295,-0.3227772068954755,3.35063652301562,-0.08144731718816471,0.036916819296822626,-1.1317574422993255,1.2676011393842441,-0.20132948448448468,-0.4665116478934158,-0.10132100472084841,3.0360202880874745,1.0407166564438557,0.09554385979269663,1.590116447393389,-0.868413390715352,0.036916819296822626,-0.9772037308061117,-0.2416356936301747,-0.20132948448448468,0.6259248892678739,-0.633579801148074,0.01729293365438732,0.8265153967127852,-0.2214607347757375,0.01729293365438732,-1.1540560850036303,-0.40463665770934043,0.4210662853564488,0.3264777895796106,0.036916819296822626,0.01729293365438732,0.250123887782108,-0.04182621575808879 | 3,329 |
Negative regulation of rna catabolic process | 11 | 34 | 2.437621 | 0.014784 | Q92804,P67809,P98175,O60506,Q14103,P35637,P16989,Q08J23,Q13148,Q14011,Q99729 | Processes and pathways | GO Biological process | msigdb_gobp | 68,198,291,325,433,90,147,22,439,123,286 | 2844,325,2379,2132,1011,469,1600,147,90,2349,198,291,2389,598,1462,22,439,1247,123,433,724,2106,2075,3275,1775,68,286,2470,802,2728,2197,941,1190,692 | -0.8037628442848861,1.1460831559915547,-0.5079941104366322,-0.3636162385970527,0.250123887782108,0.8265153967127852,-0.10132100472084841,1.9187443654853857,2.361661969696948,-0.48722946472103856,1.6234665666051777,1.233034219287915,-0.5079941104366322,0.6443335267862096,-0.022078375983966562,3.5875674867137177,0.8805087750259135,0.09554385979269663,2.110919839474487,0.8984401573767984,0.5147268428449715,-0.34317416950457963,-0.3227772068954755,-1.6593883476911249,-0.18124171644076,2.651718065289016,1.2848393592155545,-0.5496649089080891,0.43987193147095827,-0.697025958957165,-0.3841036540358946,0.3264777895796106,0.13442672453612758,0.5519360920063213 | 3,329 |
metalloprotease | 9 | 26 | 2.435303 | 0.014879 | P22695,Q9UIQ6,Q9BYT8,Q10713,Q9NZ08,P55786,P42892,Q5JRX3,O75844 | Functions | Panther Protein class | panther_protein_class | 97,36,295,234,267,207,158,255,437 | 794,1376,437,713,554,2849,1933,97,3035,1671,158,1576,861,207,234,255,649,2156,1622,462,295,1005,2813,267,36,987 | 0.43987193147095827,0.01729293365438732,0.8805087750259135,0.5147268428449715,0.6993494746743326,-0.8037628442848861,-0.26185458923358784,2.299547646576927,-0.9772037308061117,-0.14119573105890607,1.8538694542435388,-0.08144731718816471,0.38334347232626,1.6068053843688597,1.4725073343753479,1.3876431774355307,0.5890016665615532,-0.3636162385970527,-0.10132100472084841,0.8445465421230678,1.233034219287915,0.2692700201272898,-0.7609174191294885,1.353493558594779,3.1515051189672456,0.28837759100545446 | 3,329 |
Membrane protein proteolysis | 6 | 13 | 2.427994 | 0.015183 | Q16740,Q9Y5X1,P38159,Q9NZ08,Q8TCT8,Q92542 | Processes and pathways | GO Biological process | msigdb_gobp | 322,496,168,267,49,275 | 794,879,168,519,994,322,49,1735,275,267,1563,987,496 | 0.43987193147095827,0.3644259519210431,1.788575826344145,0.7540537998227098,0.2692700201272898,1.1635348870399604,2.8751418901299015,-0.16119720617815728,1.3192259465409601,1.353493558594779,-0.061615792131849874,0.28837759100545446,0.808450700356778 | 3,329 |
Abnormality of the wrist | 11 | 36 | 2.415817 | 0.0157 | P16278,O95831,Q15125,P11047,O43909,Q7RTS9,Q9Y2D4,Q13510,P02545,Q9H6K4,P31749 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 89,2,218,319,392,306,145,82,311,282,288 | 3163,392,2206,2907,3014,437,1636,735,2,311,319,89,1380,2702,697,288,811,1603,2098,1681,2882,3072,2019,82,2431,218,1547,306,1214,2989,282,2201,1629,2644,145,1090 | -1.2212885959722362,0.9876055334156724,-0.40463665770934043,-0.8468118326324626,-0.9553403143439382,0.8805087750259135,-0.12123707025353514,0.49606792158741364,4.947263399328931,1.1809557285872447,1.1635348870399604,2.3771322660471457,0.01729293365438732,-0.697025958957165,0.5333495101832308,1.2676011393842441,0.4210662853564488,-0.10132100472084841,-0.34317416950457963,-0.14119573105890607,-0.8252617481736726,-1.0210907434410021,-0.30242511290885793,2.4847808474675808,-0.5288058395850292,1.5566548641470208,-0.061615792131849874,1.1983458113760501,0.11500534183447479,-0.911772113327617,1.3020475866709618,-0.3841036540358946,-0.10132100472084841,-0.6546795012118433,1.934898419838436,0.21171518891726354 | 3,329 |
Metallopeptidase activity | 16 | 43 | 2.415073 | 0.015732 | O75976,P22695,Q9UIQ6,Q9BYT8,O75844,Q96DE0,Q99797,Q9NZ08,Q10713,P78536,P55786,P09960,O00303,P02786,Q5JRX3,P42892 | Functions | GO Molecular function | msigdb_gomf | 190,97,36,295,437,423,462,267,234,519,207,336,334,554,255,158 | 334,1309,569,794,1376,437,190,713,554,336,2849,1933,97,3035,860,158,2385,2180,1576,861,207,519,234,255,2938,1286,649,964,1000,423,2156,1622,462,1217,295,1742,757,1005,3064,2813,267,36,987 | 1.128600403817568,0.056499799932090956,0.6810456600510115,0.43987193147095827,0.01729293365438732,0.8805087750259135,1.656706107741725,0.5147268428449715,0.6993494746743326,1.128600403817568,-0.8037628442848861,-0.26185458923358784,2.299547646576927,-0.9772037308061117,0.38334347232626,1.8538694542435388,-0.5079941104366322,-0.3841036540358946,-0.08144731718816471,0.38334347232626,1.6068053843688597,0.7540537998227098,1.4725073343753479,1.3876431774355307,-0.868413390715352,0.07604207936374303,0.5890016665615532,0.30744678607403986,0.2692700201272898,0.9163385785184769,-0.3636162385970527,-0.10132100472084841,0.8445465421230678,0.11500534183447479,1.233034219287915,-0.16119720617815728,0.49606792158741364,0.2692700201272898,-0.9991204363631442,-0.7609174191294885,1.353493558594779,3.1515051189672456,0.28837759100545446 | 3,329 |
Ascites | 6 | 30 | 2.412941 | 0.015824 | P61916,P08236,Q13510,Q14108,P04062,O15118 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 142,203,82,23,84,183 | 183,925,2376,516,1412,1094,84,203,877,1452,2932,3270,880,2708,1575,142,1387,1423,508,1281,237,717,1180,82,23,1250,1987,2468,2202,2814 | 1.6898359456674157,0.3264777895796106,-0.5079941104366322,0.7540537998227098,-0.0023720624187788543,0.19245224389382748,2.4387828133527267,1.6068053843688597,0.3644259519210431,-0.022078375983966562,-0.868413390715352,-1.5653251277560118,0.3644259519210431,-0.697025958957165,-0.08144731718816471,1.934898419838436,0.01729293365438732,-0.0023720624187788543,0.7722200535599743,0.07604207936374303,1.4555923000904791,0.5147268428449715,0.13442672453612758,2.4847808474675808,3.5875674867137177,0.09554385979269663,-0.2821176516631388,-0.5496649089080891,-0.3841036540358946,-0.7609174191294885 | 3,329 |
Regulation of pattern recognition receptor signaling pathway | 6 | 23 | 2.412479 | 0.015844 | Q9UMX0,Q9NUD5,O43657,O75955,Q07021,Q9NPR9 | Processes and pathways | GO Biological process | msigdb_gobp | 455,178,146,211,400,24 | 1167,146,2410,211,1932,2254,459,2066,400,742,1182,1252,2685,1471,1909,827,24,790,178,1518,1441,455,1921 | 0.13442672453612758,1.9187443654853857,-0.5288058395850292,1.590116447393389,-0.26185458923358784,-0.4252154935543211,0.8445465421230678,-0.3227772068954755,0.9698375183938124,0.49606792158741364,0.13442672453612758,0.09554385979269663,-0.6758281295241295,-0.022078375983966562,-0.2416356936301747,0.4210662853564488,3.55996227274714,0.4586406374483879,1.722856944340898,-0.04182621575808879,-0.0023720624187788543,0.86254428557863,-0.2416356936301747 | 3,329 |
protein modifying enzyme | 7 | 28 | 2.41118 | 0.015901 | O75718,Q9UMR5,Q6P2P2,Q92791,O60725,P50897,P13674 | Functions | Panther Protein class | panther_protein_class | 161,6,238,148,52,27,284 | 2477,2478,2246,531,429,310,1664,52,161,284,1175,27,2879,3207,1642,959,2071,2983,3023,238,1154,728,1619,148,1739,1160,6,854 | -0.570571577370704,-0.570571577370704,-0.4252154935543211,0.7358533885259184,0.8984401573767984,1.1809557285872447,-0.14119573105890607,2.8011951231396175,1.8375855545892803,1.2848393592155545,0.13442672453612758,3.35063652301562,-0.8252617481736726,-1.3117300899642415,-0.12123707025353514,0.30744678607403986,-0.3227772068954755,-0.911772113327617,-0.9553403143439382,1.4555923000904791,0.15380820539298756,0.5147268428449715,-0.10132100472084841,1.9187443654853857,-0.16119720617815728,0.15380820539298756,4.371991234571003,0.40222352433548514 | 3,329 |
Dementia | 21 | 62 | 2.410395 | 0.015935 | P61916,O43681,Q14108,P09651,P20700,P07602,Q9Y487,P22626,P06865,O15118,P17900,Q13148,Q9NQ11,P00846,Q13510,P04062,Q7LG56,P35637,O60220,P43243,O76024 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 142,391,23,410,287,37,166,167,48,183,56,439,199,71,82,84,219,90,227,488,486 | 1706,183,391,227,1038,486,1043,499,71,2090,84,1450,779,48,37,410,2587,56,287,2012,167,3249,1382,1312,90,1070,2214,1014,488,2098,1681,2263,142,717,2428,598,439,625,82,23,883,1079,821,219,3046,2363,2891,3267,1258,3157,2892,2946,2310,199,588,2694,1033,1520,2991,946,2901,166 | -0.16119720617815728,1.6898359456674157,0.9876055334156724,1.5062515283479845,0.2309390068867304,0.808450700356778,0.2309390068867304,0.7903523030093713,2.606454697302084,-0.34317416950457963,2.4387828133527267,-0.022078375983966562,0.4586406374483879,2.889869040112362,3.079474577048757,0.952037115657918,-0.633579801148074,2.771469962197346,1.2676011393842441,-0.30242511290885793,1.788575826344145,-1.4491487014145832,0.01729293365438732,0.056499799932090956,2.361661969696948,0.21171518891726354,-0.40463665770934043,0.250123887782108,0.808450700356778,-0.34317416950457963,-0.14119573105890607,-0.4252154935543211,1.934898419838436,0.5147268428449715,-0.5288058395850292,0.6443335267862096,0.8805087750259135,0.6074809899769386,2.4847808474675808,3.5875674867137177,0.3644259519210431,0.21171518891726354,0.4210662853564488,1.539881993567282,-0.9772037308061117,-0.48722946472103856,-0.8252617481736726,-1.5419664934801736,0.09554385979269663,-1.1764105997956595,-0.8252617481736726,-0.868413390715352,-0.4458404075802983,1.6234665666051777,0.6627070637091839,-0.6758281295241295,0.250123887782108,-0.04182621575808879,-0.911772113327617,0.3264777895796106,-0.8252617481736726,1.80493884277799 | 3,329 |
Cellular nitrogen compound catabolic process | 38 | 182 | 2.409888 | 0.015957 | O95831,Q9Y5A9,Q9NYY8,Q96C86,P49840,P00813,P16989,Q96F86,Q08J23,Q969T7,Q15287,Q9H773,P62312,Q99729,P31749,P30519,P52272,Q96DE0,P98175,Q9NRW3,Q14103,P08670,Q9BYJ9,Q13148,O00584,Q92804,P67809,O60506,Q13126,P51114,P35637,P09601,P07910,P51116,Q9BRP8,Q9NRN7,P17844,Q14011 | Processes and pathways | GO Biological process | msigdb_gobp | 2,261,528,526,395,268,147,21,22,149,401,25,415,286,288,32,414,423,291,426,433,55,443,439,62,68,198,325,77,345,90,94,469,355,357,503,500,123 | 2844,3067,2928,2286,3148,2087,62,1310,832,325,2379,2168,2250,778,2132,1845,1011,2,2554,2654,268,2252,901,469,55,2213,94,2254,1600,3017,1380,147,500,2818,1098,1175,2852,558,32,288,2739,991,90,3255,1973,2623,1974,2349,395,1314,2487,345,355,785,414,1536,2566,2263,739,415,2327,2352,198,291,2389,2355,1542,3155,2572,598,1543,1462,22,2104,1246,1611,77,439,1247,1427,994,741,123,433,3073,1182,960,401,2433,724,2106,2267,1351,1616,2918,3209,1733,1818,2777,1319,1734,1352,2075,821,1617,2467,1988,3024,613,2306,1585,1108,3275,1109,1989,2468,2232,1819,1551,2435,2110,1775,68,1472,1955,524,149,2237,1026,526,423,21,2275,286,2438,2579,752,788,654,357,2865,2511,1780,2752,443,2726,1829,1652,2470,802,1435,2728,25,2197,941,2198,2867,2642,2782,1328,1403,1697,503,426,1302,528,1190,1088,2838,1304,691,1191,2610,3011,2760,692,2317,923,759,261,1090,3272 | 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| 3,329 |
Protease | 24 | 84 | 2.388382 | 0.016923 | Q96K76,Q9NZ08,Q96RU2,P07858,P28074,Q9HB40,P10619,P42892,Q9UIQ6,Q9BYT8,P42785,Q4J6C6,Q96FZ2,Q8TCT8,O75976,Q16740,Q9H3G5,P53634,P55786,P28072,P09960,O00303,Q5JRX3,O14773 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 259,267,140,15,269,18,29,158,36,295,38,292,47,49,190,322,69,73,207,205,336,334,255,125 | 334,1309,125,794,1376,437,190,713,2617,15,336,29,2849,1933,555,205,269,3035,2420,1603,957,1760,38,158,1852,2977,2385,2059,1576,1680,861,73,2980,207,356,519,3319,1424,2066,2391,2680,1812,322,292,255,1817,2466,2541,649,3279,2634,49,1735,2112,964,3118,1084,1361,47,259,2156,140,1622,653,2946,462,295,69,1742,2196,871,18,2868,1005,3064,1629,2813,267,36,2341,1921,2902,987,1884 | 1.128600403817568,0.056499799932090956,2.0791412514311314,0.43987193147095827,0.01729293365438732,0.8805087750259135,1.656706107741725,0.5147268428449715,-0.6546795012118433,3.792393479986781,1.128600403817568,3.308276986291303,-0.8037628442848861,-0.26185458923358784,0.6993494746743326,1.6068053843688597,1.3363745627961907,-0.9772037308061117,-0.5288058395850292,-0.10132100472084841,0.30744678607403986,-0.18124171644076,3.0650096063498165,1.8538694542435388,-0.2214607347757375,-0.911772113327617,-0.5079941104366322,-0.3227772068954755,-0.08144731718816471,-0.14119573105890607,0.38334347232626,2.576169488318419,-0.911772113327617,1.6068053843688597,1.0759646908980987,0.7540537998227098,-3.6794446794702353,-0.0023720624187788543,-0.3227772068954755,-0.5079941104366322,-0.6758281295241295,-0.20132948448448468,1.1635348870399604,1.233034219287915,1.3876431774355307,-0.20132948448448468,-0.5496649089080891,-0.5915261061872295,0.5890016665615532,-1.6830633641044765,-0.6546795012118433,2.8751418901299015,-0.16119720617815728,-0.34317416950457963,0.30744678607403986,-1.1095143380892818,0.21171518891726354,0.036916819296822626,2.9045756177690114,1.3705830562896129,-0.3636162385970527,1.9510268020575328,-0.10132100472084841,0.5890016665615532,-0.868413390715352,0.8445465421230678,1.233034219287915,2.6366521005850774,-0.16119720617815728,-0.3841036540358946,0.38334347232626,3.6425673029511563,-0.8037628442848861,0.2692700201272898,-0.9991204363631442,-0.10132100472084841,-0.7609174191294885,1.353493558594779,3.1515051189672456,-0.4665116478934158,-0.2416356936301747,-0.8252617481736726,0.28837759100545446,-0.2214607347757375 | 3,329 |
EF-Hand 1, calcium-binding site [IPR018247] | 18 | 40 | 2.371338 | 0.017724 | Q9UBV8,P12814,O75340,Q15293,P41208,Q13813,Q14257,Q9BRK5,P17655,Q96AY3,O43707,P0DP25,O43852,Q02818,P80303,Q96D71,Q9NWM8,Q9Y680 | Sequence | InterPro Binding site | interpro_binding_site | 530,695,422,723,326,563,80,406,555,629,553,312,151,87,26,285,188,257 | 553,151,422,952,1064,1712,2617,312,695,3241,1452,555,3124,1144,3018,326,1715,1178,26,87,1806,563,80,3243,723,863,1467,1951,629,285,1650,406,755,1877,188,2002,896,530,1089,257 | 0.6993494746743326,1.9025645408220684,0.9342041833231993,0.30744678607403986,0.21171518891726354,-0.16119720617815728,-0.6546795012118433,1.1809557285872447,0.5333495101832308,-1.426096499582426,-0.022078375983966562,0.6993494746743326,-1.1317574422993255,0.15380820539298756,-0.9553403143439382,1.1460831559915547,-0.16119720617815728,0.13442672453612758,3.364719210270262,2.423404607484258,-0.20132948448448468,0.6993494746743326,2.5153331882484165,-1.426096499582426,0.5147268428449715,0.38334347232626,-0.022078375983966562,-0.26185458923358784,0.6074809899769386,1.2848393592155545,-0.12123707025353514,0.9698375183938124,0.49606792158741364,-0.2214607347757375,1.6732846853550996,-0.2821176516631388,0.3644259519210431,0.7540537998227098,0.21171518891726354,1.3876431774355307 | 3,329 |
Cristae formation | 13 | 20 | 2.364862 | 0.018037 | P06576,Q13505,P00846,Q9NX63,Q16891,O75431,P56385,O75947,P36542,O75964,P24539,Q5XKP0,Q9BUR5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 795,35,71,492,725,362,642,677,903,112,902,402,281 | 362,677,112,71,795,1045,902,2704,903,2486,2668,1457,642,35,725,402,281,1834,492,949 | 1.0583565200530796,0.5519360920063213,2.2213738074871006,2.606454697302084,0.43987193147095827,0.2309390068867304,0.34547078437245365,-0.697025958957165,0.34547078437245365,-0.570571577370704,-0.6758281295241295,-0.022078375983966562,0.5890016665615532,3.1515051189672456,0.5147268428449715,0.9698375183938124,1.3020475866709618,-0.20132948448448468,0.808450700356778,0.3264777895796106 | 3,329 |
Intermediate filament | 6 | 19 | 2.35903 | 0.018323 | P20700,P07196,Q03252,Q16352,P08670,P07197 | Localization | GO Cellular component | msigdb_gocc | 287,130,230,305,55,187 | 1093,311,130,187,55,1453,2659,287,623,2217,2880,2532,1806,230,2393,305,799,2122,1089 | 0.19245224389382748,1.1809557285872447,2.0312870262355047,1.6732846853550996,2.771469962197346,-0.022078375983966562,-0.6758281295241295,1.2676011393842441,0.6074809899769386,-0.40463665770934043,-0.8252617481736726,-0.5915261061872295,-0.20132948448448468,1.5062515283479845,-0.5079941104366322,1.1983458113760501,0.43987193147095827,-0.34317416950457963,0.21171518891726354 | 3,329 |
Negative regulation of mrna processing | 12 | 22 | 2.358527 | 0.018348 | Q13242,Q13247,Q16629,P38159,P98175,P22626,P61978,P26368,Q5VTR2,Q15287,Q07021,O75150 | Processes and pathways | GO Biological process | msigdb_gobp | 248,546,798,168,291,167,229,809,888,401,400,621 | 1788,924,621,1170,1274,167,809,1797,168,229,291,400,1544,2712,248,546,401,798,888,1902,1352,2277 | -0.20132948448448468,0.3264777895796106,0.6074809899769386,0.13442672453612758,0.07604207936374303,1.788575826344145,0.4210662853564488,-0.20132948448448468,1.788575826344145,1.5062515283479845,1.233034219287915,0.9698375183938124,-0.061615792131849874,-0.697025958957165,1.4046740427964144,0.7176186653015377,0.9698375183938124,0.43987193147095827,0.3644259519210431,-0.2416356936301747,0.036916819296822626,-0.4252154935543211 | 3,329 |
Abnormal femoral neck morphology | 13 | 39 | 2.358511 | 0.018348 | P16278,O75718,O95831,Q9Y487,P02545,P04066,O75431,O43909,Q9Y619,Q7RTS9,Q9Y2D4,Q96HY6,O00754 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 89,161,2,166,311,40,362,392,79,306,145,405,150 | 3122,150,392,3014,362,161,437,622,2,311,40,89,2702,2955,2136,1071,2957,2384,1147,2879,1016,2773,2431,2681,3022,306,525,629,405,2989,2275,670,2201,1629,145,2647,166,1090,79 | -1.1317574422993255,1.9025645408220684,0.9876055334156724,-0.9553403143439382,1.0583565200530796,1.8375855545892803,0.8805087750259135,0.6074809899769386,4.947263399328931,1.1809557285872447,3.0069513662975234,2.3771322660471457,-0.697025958957165,-0.890066718141344,-0.3636162385970527,0.21171518891726354,-0.890066718141344,-0.5079941104366322,0.15380820539298756,-0.8252617481736726,0.250123887782108,-0.7395703247870165,-0.5288058395850292,-0.6758281295241295,-0.9553403143439382,1.1983458113760501,0.7540537998227098,0.6074809899769386,0.9698375183938124,-0.911772113327617,-0.4252154935543211,0.5704867554835045,-0.3841036540358946,-0.10132100472084841,1.934898419838436,-0.6546795012118433,1.80493884277799,0.21171518891726354,2.530575692978956 | 3,329 |
Cytochrome complex | 9 | 18 | 2.358172 | 0.018365 | P22695,P47985,O14949,P14406,Q7KZN9,P20674,P13073,P00403,Q9UDW1 | Localization | GO Cellular component | msigdb_gocc | 97,384,136,169,745,517,680,499,221 | 2045,793,136,499,1415,1753,1095,680,169,1571,1796,517,97,1671,384,745,221,2695 | -0.3227772068954755,0.43987193147095827,1.9671296097282782,0.7903523030093713,-0.0023720624187788543,-0.18124171644076,0.19245224389382748,0.5519360920063213,1.7721862323247783,-0.08144731718816471,-0.20132948448448468,0.7540537998227098,2.299547646576927,-0.14119573105890607,1.0053413016312243,0.49606792158741364,1.539881993567282,-0.6758281295241295 | 3,329 |
Organic acid transmembrane transporter activity | 11 | 21 | 2.354065 | 0.018569 | P08183,Q9H2J7,Q9UJS0,P53985,P41440,Q9Y619,Q9H2D1,P08195,Q9UBX3,Q96QD8,O95563 | Functions | GO Molecular function | msigdb_gomf | 66,260,657,102,459,79,111,780,708,511,593 | 2374,2788,952,593,66,780,459,2454,102,1018,1727,2305,1869,511,111,260,828,1220,708,657,79 | -0.5079941104366322,-0.7609174191294885,0.30744678607403986,0.6443335267862096,2.6667623059751864,0.4586406374483879,0.8445465421230678,-0.5496649089080891,2.283960358788461,0.250123887782108,-0.16119720617815728,-0.4458404075802983,-0.2214607347757375,0.7722200535599743,2.2370562287908466,1.3705830562896129,0.4210662853564488,0.11500534183447479,0.5333495101832308,0.5890016665615532,2.530575692978956 | 3,329 |
Regulation of rna splicing | 30 | 92 | 2.353204 | 0.018612 | Q96PU8,P31943,O75525,Q15287,Q07021,Q13595,P09651,P38159,P22626,P98175,Q9BWF3,O60828,P52597,Q5BKZ1,P98179,Q07666,Q07955,Q15007,P51114,P35637,Q9UHX1,P51116,P61978,Q92841,P62995,P55795,Q13242,P17844,P31942,Q14011 | Processes and pathways | GO Biological process | msigdb_gobp | 134,138,139,401,400,416,410,168,167,291,308,431,176,182,57,460,327,208,345,90,381,355,229,490,241,243,248,500,122,123 | 924,431,778,1170,139,975,410,1530,781,500,2055,2347,167,1935,809,1797,2956,1312,122,138,90,168,1015,2097,345,355,1240,176,904,1680,243,229,2937,2711,241,931,1495,291,57,2389,1281,598,400,460,327,1544,2104,2356,1246,2712,248,797,546,661,416,123,1389,1464,1945,208,401,1104,995,798,1860,3076,182,3023,3275,823,628,1289,703,1357,490,1472,1473,1824,134,511,1259,1324,2277,308,3219,1745,2925,381,1919,1443,692,1090 | 0.3264777895796106,0.8984401573767984,0.4586406374483879,0.13442672453612758,1.9510268020575328,0.28837759100545446,0.952037115657918,-0.061615792131849874,0.4586406374483879,0.7903523030093713,-0.3227772068954755,-0.48722946472103856,1.788575826344145,-0.26185458923358784,0.4210662853564488,-0.20132948448448468,-0.890066718141344,0.056499799932090956,2.110919839474487,1.9671296097282782,2.361661969696948,1.788575826344145,0.250123887782108,-0.34317416950457963,1.1110864980035515,1.0759646908980987,0.09554385979269663,1.722856944340898,0.34547078437245365,-0.14119573105890607,1.4216757723522286,1.5062515283479845,-0.868413390715352,-0.697025958957165,1.4386484853059598,0.3264777895796106,-0.04182621575808879,1.233034219287915,2.7416602578229923,-0.5079941104366322,0.07604207936374303,0.6443335267862096,0.9698375183938124,0.8445465421230678,1.1460831559915547,-0.061615792131849874,-0.34317416950457963,-0.48722946472103856,0.09554385979269663,-0.697025958957165,1.4046740427964144,0.43987193147095827,0.7176186653015377,0.5704867554835045,0.952037115657918,2.110919839474487,0.01729293365438732,-0.022078375983966562,-0.26185458923358784,1.6068053843688597,0.9698375183938124,0.19245224389382748,0.2692700201272898,0.43987193147095827,-0.2214607347757375,-1.0210907434410021,1.706359996334182,-0.9553403143439382,-1.6593883476911249,0.4210662853564488,0.6074809899769386,0.07604207936374303,0.5333495101832308,0.036916819296822626,0.808450700356778,-0.022078375983966562,-0.022078375983966562,-0.20132948448448468,1.9832069398504246,0.7722200535599743,0.09554385979269663,0.056499799932090956,-0.4252154935543211,1.1983458113760501,-1.3344853226815454,-0.16119720617815728,-0.8468118326324626,1.0230449629802814,-0.2416356936301747,-0.0023720624187788543,0.5519360920063213,0.21171518891726354 | 3,329 |
Disproportionate short stature | 10 | 25 | 2.350019 | 0.018772 | O75718,Q15125,O00116,Q7LGA3,O43909,Q7RTS9,Q32P28,Q9UHX1,P16278,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 161,218,72,265,392,306,379,381,89,155 | 72,875,392,3014,161,622,877,89,2559,2563,2384,1346,1250,2431,218,155,379,1547,265,306,3210,405,3280,1630,381 | 2.576169488318419,0.3644259519210431,0.9876055334156724,-0.9553403143439382,1.8375855545892803,0.6074809899769386,0.3644259519210431,2.3771322660471457,-0.6125287588483042,-0.6125287588483042,-0.5079941104366322,0.036916819296822626,0.09554385979269663,-0.5288058395850292,1.5566548641470208,1.8863588470765684,1.0230449629802814,-0.061615792131849874,1.353493558594779,1.1983458113760501,-1.3117300899642415,0.9698375183938124,-1.6830633641044765,-0.10132100472084841,1.0230449629802814 | 3,329 |
mRNA splicing factor | 31 | 63 | 2.34778 | 0.018886 | Q96PU8,O75525,P33240,Q15287,P62312,Q13595,Q8IWZ8,Q13243,Q13247,P38159,Q93062,Q9BWF3,O75934,P23246,O95391,P98179,Q8WXF1,Q96PK6,Q92804,Q07666,Q07955,Q15233,P35637,Q8WWY3,Q01844,P62995,Q8IY67,Q13242,Q14011,Q9BZJ0,Q15428 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 134,139,783,401,415,416,664,797,546,168,300,308,676,556,180,57,453,323,68,460,327,599,90,615,237,241,628,248,123,772,509 | 3230,2343,1198,1843,1170,139,1888,676,1709,180,2657,975,2415,2345,2347,556,783,90,168,2221,415,3055,2492,241,1495,57,1281,237,460,327,1544,2104,2712,1282,248,797,546,416,123,1686,599,401,3044,509,1813,995,798,2938,864,664,1690,628,615,453,68,300,323,134,308,772,1782,1438,2732 | -1.3801721289355482,-0.48722946472103856,0.11500534183447479,-0.2214607347757375,0.13442672453612758,1.9510268020575328,-0.2416356936301747,0.5519360920063213,-0.16119720617815728,1.706359996334182,-0.6758281295241295,0.28837759100545446,-0.5288058395850292,-0.48722946472103856,-0.48722946472103856,0.6993494746743326,0.4586406374483879,2.361661969696948,1.788575826344145,-0.40463665770934043,0.952037115657918,-0.9991204363631442,-0.570571577370704,1.4386484853059598,-0.04182621575808879,2.7416602578229923,0.07604207936374303,1.4555923000904791,0.8445465421230678,1.1460831559915547,-0.061615792131849874,-0.34317416950457963,-0.697025958957165,0.07604207936374303,1.4046740427964144,0.43987193147095827,0.7176186653015377,0.952037115657918,2.110919839474487,-0.14119573105890607,0.6443335267862096,0.9698375183938124,-0.9772037308061117,0.7722200535599743,-0.20132948448448468,0.2692700201272898,0.43987193147095827,-0.868413390715352,0.38334347232626,0.5704867554835045,-0.14119573105890607,0.6074809899769386,0.6259248892678739,0.86254428557863,2.651718065289016,1.215705265275244,1.1635348870399604,1.9832069398504246,1.1983458113760501,0.4773725767590705,-0.18124171644076,-0.0023720624187788543,-0.697025958957165 | 3,329 |
serine protease | 7 | 16 | 2.34687 | 0.018932 | Q16740,Q9H3G5,P42785,Q4J6C6,Q9HB40,P10619,O14773 | Functions | Panther Protein class | panther_protein_class | 322,69,38,292,18,29,125 | 125,29,2848,2482,2420,1603,38,2977,356,322,292,3279,2234,69,18,2757 | 2.0791412514311314,3.308276986291303,-0.8037628442848861,-0.570571577370704,-0.5288058395850292,-0.10132100472084841,3.0650096063498165,-0.911772113327617,1.0759646908980987,1.1635348870399604,1.233034219287915,-1.6830633641044765,-0.40463665770934043,2.6366521005850774,3.6425673029511563,-0.7182732647998294 | 3,329 |
Organic cyclic compound catabolic process | 40 | 190 | 2.344453 | 0.019055 | O95831,Q9Y5A9,Q9NYY8,Q96C86,P49840,P00813,P16989,Q96F86,Q08J23,Q969T7,Q15287,Q9H773,P62312,Q99729,P31749,P30519,P52272,Q96DE0,P98175,Q9NRW3,Q14103,P08670,Q9BYJ9,Q13148,O00584,P21964,Q92804,P67809,O60506,Q13126,P51114,Q8WTV0,P35637,P09601,P07910,P51116,Q9BRP8,Q9NRN7,P17844,Q14011 | Processes and pathways | GO Biological process | msigdb_gobp | 2,261,528,526,395,268,147,21,22,149,401,25,415,286,288,32,414,423,291,426,433,55,443,439,62,320,68,198,325,77,345,86,90,94,469,355,357,503,500,123 | 2844,3067,2928,2286,3148,2087,62,1310,832,2377,325,2379,2168,2250,778,2132,1845,1011,2,2554,2654,268,2252,901,469,55,3240,1892,2213,94,2254,1600,3017,2932,147,500,320,2818,1175,2852,558,32,288,2739,3254,991,90,3255,1973,2623,1974,2349,395,1314,2487,345,355,785,414,1536,2566,2263,739,415,2327,2352,198,291,2389,2355,1542,1244,3155,2572,598,1543,1462,22,2104,1246,1611,77,439,1247,1427,994,741,123,433,3073,1182,960,1501,401,2433,724,2106,2267,1351,1616,2918,3209,1733,1818,2777,1319,1734,1352,2075,821,1617,2467,1988,3024,613,2306,1585,1108,3275,1109,1989,2468,2232,1819,1550,1551,2435,2110,86,1775,68,1472,1955,524,149,2237,1026,526,423,21,2275,286,2438,2579,752,788,654,357,2865,2511,1780,2752,443,2726,1829,1652,2470,802,1435,2728,25,2197,941,2198,2867,2642,2782,1328,1403,1697,503,426,1302,528,1190,1088,2838,1304,691,1191,2610,3011,2760,692,2317,923,759,261,1090,3272 | 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| 3,329 |
Cellular lipid metabolic process | 39 | 209 | 2.334276 | 0.019581 | P23786,Q8N4Q0,Q96PU8,P35790,O75521,P14174,P61916,O94788,Q9HB40,Q14914,Q9NPH0,P50897,Q8NBX0,P07602,Q13011,Q15067,P04066,Q8N8N7,P06865,Q9NRA0,P17900,Q8NCC3,P07099,Q96G23,P07686,O00116,Q9NZ01,P06280,Q8NHP8,Q13510,P04062,Q8WTV0,Q53H12,P16278,Q06136,Q16739,Q10713,Q07954,Q9HCL2 | Processes and pathways | GO Biological process | msigdb_gobp | 132,5,134,264,137,11,142,273,18,19,153,27,33,37,165,39,40,172,48,53,56,58,186,63,191,72,200,76,78,82,84,86,214,89,91,231,234,244,256 | 497,3269,72,2286,3122,3320,2733,950,3290,875,637,1196,1374,2318,1664,2130,422,2448,1169,137,3282,2412,437,856,273,735,466,2050,399,3158,2653,833,84,40,1570,3323,2170,76,48,186,37,191,3240,3309,1272,2850,11,2451,2483,3314,89,1380,555,56,3124,878,2419,1096,132,2818,2322,2323,487,2177,2956,3288,1800,1176,288,1313,3254,991,264,458,2141,1533,2527,1204,411,2666,2325,2796,1122,2978,1854,1856,1147,27,2098,507,1575,2960,1343,2426,2530,2880,142,2457,814,3250,2882,699,2627,3155,2459,91,1543,244,2103,234,165,3326,3002,82,2499,3278,19,39,572,2502,1126,417,1210,2106,231,1728,386,1583,843,214,817,767,1901,2576,2305,3307,2721,728,3046,2234,5,172,2542,1291,33,58,2436,1773,78,1820,86,2891,600,1156,2112,3267,1556,1620,1002,63,2365,3298,134,1157,3007,1590,2401,2831,1189,1131,2195,688,1261,2158,3327,425,754,2337,1325,1592,358,2160,18,2642,256,2693,153,1914,53,895,1880,2694,672,1481,200,1033,970,1117,1407,853,944,1836,2475,947,1442,2125,898,1840,874 | 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| 3,329 |
Mitochondrial membrane organization | 22 | 49 | 2.332202 | 0.01969 | P52789,P12235,Q5HYI7,Q9P0J0,Q9NS69,P49840,Q9Y5J9,Q5XKP0,Q9BUR5,Q9UII2,P45880,Q13505,P0DP25,Q16891,Q53H12,Q15070,O60220,Q9NX63,O75431,O95140,O14737,Q9Y5J7 | Processes and pathways | GO Biological process | msigdb_gobp | 765,763,648,792,9,395,272,402,281,550,34,35,312,725,214,470,227,492,362,235,498,252 | 3248,498,227,1038,362,1525,235,1064,2133,2210,2211,2213,312,763,1045,1602,2592,2974,2486,2666,34,395,3093,1147,765,1543,35,470,725,887,214,648,402,1287,1467,1951,1553,281,789,9,1834,492,792,550,2695,987,949,252,272 | -1.4491487014145832,0.7903523030093713,1.5062515283479845,0.2309390068867304,1.0583565200530796,-0.061615792131849874,1.4555923000904791,0.21171518891726354,-0.3636162385970527,-0.40463665770934043,-0.40463665770934043,-0.40463665770934043,1.1809557285872447,0.4773725767590705,0.2309390068867304,-0.10132100472084841,-0.633579801148074,-0.911772113327617,-0.570571577370704,-0.6758281295241295,3.1801811755749765,0.9876055334156724,-1.0651934264465188,0.15380820539298756,0.4773725767590705,-0.061615792131849874,3.1515051189672456,0.8265153967127852,0.5147268428449715,0.3644259519210431,1.590116447393389,0.5890016665615532,0.9698375183938124,0.07604207936374303,-0.022078375983966562,-0.26185458923358784,-0.061615792131849874,1.3020475866709618,0.4586406374483879,4.0728316680909415,-0.20132948448448468,0.808450700356778,0.4586406374483879,0.7176186653015377,-0.6758281295241295,0.28837759100545446,0.3264777895796106,1.4046740427964144,1.3363745627961907 | 3,329 |
Aplasia hypoplasia involving the vertebral column | 6 | 16 | 2.328062 | 0.019909 | O95831,P04066,O43909,Q7RTS9,P08236,P16278 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,40,392,306,203,89 | 2734,392,3014,2,40,203,877,89,1603,2622,1250,2303,662,306,405,670 | -0.7182732647998294,0.9876055334156724,-0.9553403143439382,4.947263399328931,3.0069513662975234,1.6068053843688597,0.3644259519210431,2.3771322660471457,-0.10132100472084841,-0.6546795012118433,0.09554385979269663,-0.4458404075802983,0.5704867554835045,1.1983458113760501,0.9698375183938124,0.5704867554835045 | 3,329 |
Electron transport | 16 | 49 | 2.319608 | 0.020362 | P22695,O95168,O43676,O75380,P47985,O14949,Q9Y6M9,O96000,Q9H1E5,O75438,Q6DKK2,Q9H3N1,Q96CU9,Q86Y39,O43169,Q9UDW1 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 97,409,189,382,384,136,202,393,463,485,339,480,280,380,156,221 | 1660,2045,136,156,777,189,2906,807,382,485,638,1335,409,1847,1232,393,499,2090,1415,2850,1571,2452,2012,2558,97,3166,1382,1671,2875,2141,384,2915,1279,1315,1210,1318,1946,2629,339,380,280,1399,1297,463,480,1058,792,221,202 | -0.14119573105890607,-0.3227772068954755,1.9671296097282782,1.8701271848764083,0.4586406374483879,1.656706107741725,-0.8468118326324626,0.4210662853564488,1.0053413016312243,0.808450700356778,0.5890016665615532,0.036916819296822626,0.952037115657918,-0.2214607347757375,0.09554385979269663,0.9876055334156724,0.7903523030093713,-0.34317416950457963,-0.0023720624187788543,-0.8037628442848861,-0.08144731718816471,-0.5496649089080891,-0.30242511290885793,-0.6125287588483042,2.299547646576927,-1.2212885959722362,0.01729293365438732,-0.14119573105890607,-0.8252617481736726,-0.3636162385970527,1.0053413016312243,-0.8468118326324626,0.07604207936374303,0.056499799932090956,0.11500534183447479,0.056499799932090956,-0.26185458923358784,-0.6546795012118433,1.128600403817568,1.0230449629802814,1.3020475866709618,0.01729293365438732,0.07604207936374303,0.8445465421230678,0.8265153967127852,0.2309390068867304,0.4586406374483879,1.539881993567282,1.6234665666051777 | 3,329 |
Smad protein signal transduction | 6 | 9 | 2.316629 | 0.020524 | Q96PK6,Q9UIQ6,Q93062,Q01082,Q07954,P08670 | Processes and pathways | GO Biological process | msigdb_gobp | 323,36,300,520,244,55 | 55,2556,1538,520,244,650,300,323,36 | 2.771469962197346,-0.6125287588483042,-0.061615792131849874,0.7540537998227098,1.4216757723522286,0.5890016665615532,1.215705265275244,1.1635348870399604,3.1515051189672456 | 3,329 |
Intracellular protein transmembrane transport | 6 | 21 | 2.314462 | 0.020642 | Q99595,O95831,O75381,Q15629,O43615,Q15388 | Processes and pathways | GO Biological process | msigdb_gobp | 1,2,253,209,360,314 | 449,360,1093,253,1525,2,1043,2874,1147,3169,2773,1683,314,209,887,3289,1023,1995,1,1479,945 | 0.86254428557863,1.0583565200530796,0.19245224389382748,1.3876431774355307,-0.061615792131849874,4.947263399328931,0.2309390068867304,-0.8252617481736726,0.15380820539298756,-1.2212885959722362,-0.7395703247870165,-0.14119573105890607,1.1809557285872447,1.6068053843688597,0.3644259519210431,-1.7544772036562493,0.250123887782108,-0.2821176516631388,5.020181225676923,-0.022078375983966562,0.3264777895796106 | 3,329 |
Ensheathment of neurons | 8 | 25 | 2.314462 | 0.020642 | P07686,Q96PU8,P53634,P17028,Q92542,Q9NR77,P10909,P31749 | Processes and pathways | GO Biological process | msigdb_gobp | 191,134,73,239,275,116,343,288 | 875,778,952,191,343,239,3052,288,1417,2563,1855,73,2265,2266,2499,434,2393,1950,275,2114,134,116,1837,2610,987 | 0.3644259519210431,0.4586406374483879,0.30744678607403986,1.656706107741725,1.1110864980035515,1.4386484853059598,-0.9991204363631442,1.2676011393842441,-0.0023720624187788543,-0.6125287588483042,-0.2214607347757375,2.576169488318419,-0.4252154935543211,-0.4252154935543211,-0.570571577370704,0.8984401573767984,-0.5079941104366322,-0.26185458923358784,1.3192259465409601,-0.34317416950457963,1.9832069398504246,2.1899368722600734,-0.20132948448448468,-0.633579801148074,0.28837759100545446 | 3,329 |
Protein insertion into er membrane | 6 | 12 | 2.294503 | 0.021762 | Q8N4V1,P46379,Q96A33,Q15629,O43681,Q15006 | Processes and pathways | GO Biological process | msigdb_gobp | 354,98,525,209,391,547 | 1791,391,712,98,1683,547,209,1466,354,1905,525,1700 | -0.20132948448448468,0.9876055334156724,0.5147268428449715,2.299547646576927,-0.14119573105890607,0.7176186653015377,1.6068053843688597,-0.022078375983966562,1.093541305136819,-0.2416356936301747,0.7540537998227098,-0.14119573105890607 | 3,329 |
Macroglossia | 12 | 37 | 2.292011 | 0.021905 | P07686,P16278,P61978,Q96A33,Q7LGA3,P04066,Q10713,P10253,O60828,O00754,O75648,P31749 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 191,89,229,525,265,40,234,109,431,150,341,288 | 2872,3122,150,2203,2205,431,341,735,40,191,109,89,2257,2012,288,2139,1071,2387,229,2299,2596,234,1857,2500,521,265,2543,525,1025,1157,2275,1829,607,2038,1439,3050,1061 | -0.8252617481736726,-1.1317574422993255,1.9025645408220684,-0.40463665770934043,-0.40463665770934043,0.8984401573767984,1.1110864980035515,0.49606792158741364,3.0069513662975234,1.656706107741725,2.2370562287908466,2.3771322660471457,-0.4252154935543211,-0.30242511290885793,1.2676011393842441,-0.3636162385970527,0.21171518891726354,-0.5079941104366322,1.5062515283479845,-0.4458404075802983,-0.633579801148074,1.4725073343753479,-0.2214607347757375,-0.570571577370704,0.7540537998227098,1.353493558594779,-0.5915261061872295,0.7540537998227098,0.250123887782108,0.15380820539298756,-0.4252154935543211,-0.20132948448448468,0.6443335267862096,-0.30242511290885793,-0.0023720624187788543,-0.9772037308061117,0.2309390068867304 | 3,329 |
EF-hand domain [IPR002048] | 22 | 49 | 2.291988 | 0.021906 | Q9UBV8,Q9UJS0,Q9BRK5,O43852,P80303,Q96D71,O75340,Q13813,P17655,O43707,P0DP25,Q9NWM8,P60660,Q0IIM8,P12814,Q15293,P41208,Q14257,Q02818,O75071,Q96AY3,Q9Y680 | Sequence | InterPro Domain | interpro_domain | 530,657,406,151,26,285,422,563,555,553,312,188,571,451,695,723,326,80,87,101,629,257 | 553,151,101,422,952,1064,1712,2617,312,695,3241,1452,555,3124,1144,3018,2997,326,1715,1178,571,26,87,1806,451,563,80,3243,723,1392,863,1467,1951,1083,1773,629,285,2401,1650,406,755,1877,188,2002,896,530,657,1089,257 | 0.6993494746743326,1.9025645408220684,2.283960358788461,0.9342041833231993,0.30744678607403986,0.21171518891726354,-0.16119720617815728,-0.6546795012118433,1.1809557285872447,0.5333495101832308,-1.426096499582426,-0.022078375983966562,0.6993494746743326,-1.1317574422993255,0.15380820539298756,-0.9553403143439382,-0.9335298774233274,1.1460831559915547,-0.16119720617815728,0.13442672453612758,0.6810456600510115,3.364719210270262,2.423404607484258,-0.20132948448448468,0.86254428557863,0.6993494746743326,2.5153331882484165,-1.426096499582426,0.5147268428449715,0.01729293365438732,0.38334347232626,-0.022078375983966562,-0.26185458923358784,0.21171518891726354,-0.18124171644076,0.6074809899769386,1.2848393592155545,-0.5079941104366322,-0.12123707025353514,0.9698375183938124,0.49606792158741364,-0.2214607347757375,1.6732846853550996,-0.2821176516631388,0.3644259519210431,0.7540537998227098,0.5890016665615532,0.21171518891726354,1.3876431774355307 | 3,329 |
Incoordination | 22 | 78 | 2.279081 | 0.022662 | Q01105,P06753,O75503,O43681,O00754,P07602,O75340,Q15067,Q7RTS9,P11047,P00846,Q9Y619,Q6DKK2,Q13510,P04062,Q7LG56,Q10713,O95140,Q9NR77,Q9UJX6,P37198,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 254,258,14,391,150,37,422,39,306,319,71,79,339,82,84,219,234,235,116,246,378,125 | 447,2762,150,125,2734,1227,391,1523,422,14,1412,235,2766,71,84,258,37,319,763,2588,2012,2453,1382,1312,378,2527,1014,2624,1718,2454,2263,2530,1344,1539,254,2428,2596,978,234,625,82,2574,3199,39,2393,2029,339,2359,821,219,306,1353,2985,3184,1820,1397,2603,1258,2892,2401,966,2831,1297,3145,607,2868,1368,1783,116,1302,1330,1033,1520,3048,1836,246,1061,79 | 0.86254428557863,-0.7395703247870165,1.9025645408220684,2.0791412514311314,-0.7182732647998294,0.09554385979269663,0.9876055334156724,-0.061615792131849874,0.9342041833231993,3.9801481206823643,-0.0023720624187788543,1.4555923000904791,-0.7395703247870165,2.606454697302084,2.4387828133527267,1.3705830562896129,3.079474577048757,1.1635348870399604,0.4773725767590705,-0.633579801148074,-0.30242511290885793,-0.5496649089080891,0.01729293365438732,0.056499799932090956,1.0230449629802814,-0.5915261061872295,0.250123887782108,-0.6546795012118433,-0.16119720617815728,-0.5496649089080891,-0.4252154935543211,-0.5915261061872295,0.036916819296822626,-0.061615792131849874,1.3876431774355307,-0.5288058395850292,-0.633579801148074,0.28837759100545446,1.4725073343753479,0.6074809899769386,2.4847808474675808,-0.6125287588483042,-1.2890331559905834,3.0360202880874745,-0.5079941104366322,-0.30242511290885793,1.128600403817568,-0.48722946472103856,0.4210662853564488,1.539881993567282,1.1983458113760501,0.036916819296822626,-0.911772113327617,-1.2438127606249867,-0.20132948448448468,0.01729293365438732,-0.633579801148074,0.09554385979269663,-0.8252617481736726,-0.5079941104366322,0.30744678607403986,-0.7823148305441647,0.07604207936374303,-1.1540560850036303,0.6443335267862096,-0.8037628442848861,0.036916819296822626,-0.18124171644076,2.1899368722600734,0.07604207936374303,0.056499799932090956,0.250123887782108,-0.04182621575808879,-0.9772037308061117,-0.20132948448448468,1.4216757723522286,0.2309390068867304,2.530575692978956 | 3,329 |
Metalloprotease | 12 | 38 | 2.277411 | 0.022762 | P22695,Q9UIQ6,Q9BYT8,O75844,Q99797,Q9NZ08,Q10713,P55786,O00303,P02786,Q5JRX3,P42892 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 97,36,295,437,462,267,234,207,334,554,255,158 | 334,1309,569,794,1376,437,713,554,2134,2849,1933,1339,97,3035,1671,158,2180,1576,861,207,234,3073,2267,255,1286,649,1691,964,1645,2156,1622,462,2438,295,2813,267,36,987 | 1.128600403817568,0.056499799932090956,0.6810456600510115,0.43987193147095827,0.01729293365438732,0.8805087750259135,0.5147268428449715,0.6993494746743326,-0.3636162385970527,-0.8037628442848861,-0.26185458923358784,0.036916819296822626,2.299547646576927,-0.9772037308061117,-0.14119573105890607,1.8538694542435388,-0.3841036540358946,-0.08144731718816471,0.38334347232626,1.6068053843688597,1.4725073343753479,-1.0210907434410021,-0.4252154935543211,1.3876431774355307,0.07604207936374303,0.5890016665615532,-0.14119573105890607,0.30744678607403986,-0.12123707025353514,-0.3636162385970527,-0.10132100472084841,0.8445465421230678,-0.5288058395850292,1.233034219287915,-0.7609174191294885,1.353493558594779,3.1515051189672456,0.28837759100545446 | 3,329 |
Extracellular matrix organization | 12 | 32 | 2.277147 | 0.022777 | O75718,O15460,P78536,P07858,Q92542,P17655,O14936,P35613,O60568,Q32P28,P13674,P11047 | Processes and pathways | Reactome Pathways | msigdb_reactome | 161,531,519,15,275,555,552,313,310,379,284,319 | 2477,552,2585,531,310,161,1712,1233,609,2617,15,1066,319,695,284,555,3165,2559,313,957,1605,958,519,1642,1806,1496,2393,379,1619,275,1920,1224 | -0.570571577370704,0.6993494746743326,-0.633579801148074,0.7358533885259184,1.1809557285872447,1.8375855545892803,-0.16119720617815728,0.09554385979269663,0.6259248892678739,-0.6546795012118433,3.792393479986781,0.21171518891726354,1.1635348870399604,0.5333495101832308,1.2848393592155545,0.6993494746743326,-1.2212885959722362,-0.6125287588483042,1.1809557285872447,0.30744678607403986,-0.10132100472084841,0.30744678607403986,0.7540537998227098,-0.12123707025353514,-0.20132948448448468,-0.04182621575808879,-0.5079941104366322,1.0230449629802814,-0.10132100472084841,1.3192259465409601,-0.2416356936301747,0.11500534183447479 | 3,329 |
Anatomical structure maturation | 6 | 29 | 2.269405 | 0.023244 | Q9Y5A9,Q9Y2W6,O75503,P04062,Q08J23,Q15125 | Processes and pathways | GO Biological process | msigdb_gobp | 261,41,14,84,22,218 | 1844,2410,14,1412,273,84,1413,2174,1337,2483,2910,3052,1800,1417,2384,2098,1940,22,3213,434,218,1987,2464,2918,1866,3245,1033,41,261 | -0.2214607347757375,-0.5288058395850292,3.9801481206823643,-0.0023720624187788543,1.3192259465409601,2.4387828133527267,-0.0023720624187788543,-0.3841036540358946,0.036916819296822626,-0.570571577370704,-0.8468118326324626,-0.9991204363631442,-0.20132948448448468,-0.0023720624187788543,-0.5079941104366322,-0.34317416950457963,-0.26185458923358784,3.5875674867137177,-1.3344853226815454,0.8984401573767984,1.5566548641470208,-0.2821176516631388,-0.5496649089080891,-0.8468118326324626,-0.2214607347757375,-1.426096499582426,0.250123887782108,3.0069513662975234,1.3705830562896129 | 3,329 |
Electron transport chain oxphos system in mitochondria | 26 | 55 | 2.269354 | 0.023247 | P12235,O75380,P47985,O14949,O75489,O96000,P20674,P56385,P06576,Q9UII2,O95168,O14548,P14406,O75947,P13073,O75306,O43676,P00846,Q9Y6M9,Q9UDW1,O75880,P22695,Q7KZN9,O75438,O75964,P00403 | Processes and pathways | WikiPathways | msigdb_wp | 763,382,384,136,638,393,517,642,795,550,409,793,169,677,680,807,189,71,202,221,465,97,745,485,112,499 | 1660,2045,793,136,189,2906,807,382,485,638,465,677,112,1335,409,1847,1232,393,499,71,2090,2210,795,1753,1095,763,2417,680,169,1571,1796,2452,517,2012,97,902,2704,3166,1382,1671,903,384,2668,2915,1279,1457,642,1315,1318,1946,745,221,550,202,855 | -0.14119573105890607,-0.3227772068954755,0.43987193147095827,1.9671296097282782,1.656706107741725,-0.8468118326324626,0.4210662853564488,1.0053413016312243,0.808450700356778,0.5890016665615532,0.8265153967127852,0.5519360920063213,2.2213738074871006,0.036916819296822626,0.952037115657918,-0.2214607347757375,0.09554385979269663,0.9876055334156724,0.7903523030093713,2.606454697302084,-0.34317416950457963,-0.40463665770934043,0.43987193147095827,-0.18124171644076,0.19245224389382748,0.4773725767590705,-0.5288058395850292,0.5519360920063213,1.7721862323247783,-0.08144731718816471,-0.20132948448448468,-0.5496649089080891,0.7540537998227098,-0.30242511290885793,2.299547646576927,0.34547078437245365,-0.697025958957165,-1.2212885959722362,0.01729293365438732,-0.14119573105890607,0.34547078437245365,1.0053413016312243,-0.6758281295241295,-0.8468118326324626,0.07604207936374303,-0.022078375983966562,0.5890016665615532,0.056499799932090956,0.056499799932090956,-0.26185458923358784,0.49606792158741364,1.539881993567282,0.7176186653015377,1.6234665666051777,0.40222352433548514 | 3,329 |
Toe walking | 10 | 25 | 2.265677 | 0.023471 | O95831,P07602,P06753,Q8WXH0,O43681,P50402,Q01082,Q8TD16,P02545,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,37,258,565,391,369,520,177,311,90 | 391,2,311,258,37,90,2527,369,2454,1681,2263,2530,520,2801,2574,2435,3184,177,565,1514,1871,607,2693,1033,874 | 0.9876055334156724,4.947263399328931,1.1809557285872447,1.3705830562896129,3.079474577048757,2.361661969696948,-0.5915261061872295,1.0407166564438557,-0.5496649089080891,-0.14119573105890607,-0.4252154935543211,-0.5915261061872295,0.7540537998227098,-0.7609174191294885,-0.6125287588483042,-0.5288058395850292,-1.2438127606249867,1.722856944340898,0.6993494746743326,-0.04182621575808879,-0.2214607347757375,0.6443335267862096,-0.6758281295241295,0.250123887782108,0.38334347232626 | 3,329 |
Processing of capped intron containing pre mrna | 61 | 190 | 2.263984 | 0.023575 | P31943,Q86V81,P55769,Q96FV9,P33240,P14866,Q6UN15,Q15287,P62312,Q8IWZ8,P52272,Q13573,Q13243,Q01081,P09651,Q13247,P38159,P22626,O43390,Q8TBF4,Q9H2H8,Q14103,O60828,P52597,O75934,O95391,Q92733,O95400,P67809,Q8NFH4,Q07955,Q7Z3B4,Q15007,P51991,Q96EE3,Q15717,Q9BUJ2,P35637,P12270,P07910,Q9BTX1,Q9UHX1,Q8WWY3,Q8N684,P61978,P57740,P19388,P06730,Q86U42,Q9BWJ5,P62995,P55795,Q5KU26,P37198,Q13242,P17844,O15504,Q9BZJ0,O94992,Q8N1F7,Q15428 | Processes and pathways | Reactome Pathways | msigdb_reactome | 138,266,518,404,783,781,403,401,415,664,414,661,797,684,410,546,168,167,297,564,175,433,431,176,676,180,315,195,198,331,327,727,208,337,461,724,478,90,594,469,619,381,615,614,229,233,364,736,746,110,241,243,371,378,248,500,375,772,376,650,509 | 2044,1568,375,1310,2586,3230,2129,297,2343,2008,2288,1843,2206,1663,431,1665,2131,1170,1888,2699,2519,676,927,1230,1709,376,180,195,736,469,2657,975,2415,1067,410,2345,1530,594,1754,781,1273,500,1275,364,167,1935,809,1797,1850,138,783,2261,90,1675,378,168,1973,1203,1974,2423,1895,2425,337,414,176,904,1680,518,243,233,229,2221,415,3055,2062,2492,2327,1608,241,198,1243,1280,1495,2389,684,1281,1461,2676,327,1544,1462,2104,2300,1209,1282,2495,1247,248,797,546,1388,661,1725,2020,433,208,2432,401,2072,1284,3044,1104,509,1813,995,724,798,3140,371,2718,2938,403,2683,1082,727,746,1585,266,2749,1395,1354,664,2231,1289,650,614,3262,331,1293,3077,564,2031,1867,1774,615,865,2602,2965,315,1693,1695,1737,1647,461,404,939,2545,1364,1028,619,478,1779,3143,1872,110,1114,1625,2726,772,175,3219,1782,1404,2925,1370,1438,1593,381,1486,1747,2993,1443,3010,3081,2004,2317,1165,1166,2342,1090 | 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| 3,329 |
Abnormal enchondral ossification | 10 | 30 | 2.260744 | 0.023775 | O75381,P40855,O00116,P38435,O96028,O43909,Q9Y619,Q7RTS9,P08236,Q15125 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 253,383,72,394,43,392,79,306,203,218 | 72,392,3014,253,1064,43,203,877,2702,1603,394,383,1147,2773,2103,2538,1250,2431,218,2303,3022,306,3210,405,2989,1629,1630,944,2647,79 | 2.576169488318419,0.9876055334156724,-0.9553403143439382,1.3876431774355307,0.21171518891726354,2.9778023149588617,1.6068053843688597,0.3644259519210431,-0.697025958957165,-0.10132100472084841,0.9876055334156724,1.0053413016312243,0.15380820539298756,-0.7395703247870165,-0.34317416950457963,-0.5915261061872295,0.09554385979269663,-0.5288058395850292,1.5566548641470208,-0.4458404075802983,-0.9553403143439382,1.1983458113760501,-1.3117300899642415,0.9698375183938124,-0.911772113327617,-0.10132100472084841,-0.10132100472084841,0.3264777895796106,-0.6546795012118433,2.530575692978956 | 3,329 |
Abnormal conjunctiva morphology | 7 | 24 | 2.257343 | 0.023987 | P28070,P04066,Q9NZ08,P06280,Q13510,P10619,P31749 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 3,40,267,76,82,29,288 | 2379,467,554,40,2846,76,29,2255,3052,2851,2012,3034,3,3137,288,681,2978,3094,2357,82,1250,1025,316,267 | -0.5079941104366322,0.8265153967127852,0.6993494746743326,3.0069513662975234,-0.8037628442848861,2.5457958590928893,3.308276986291303,-0.4252154935543211,-0.9991204363631442,-0.8037628442848861,-0.30242511290885793,-0.9772037308061117,4.700755513120214,-1.1540560850036303,1.2676011393842441,0.5519360920063213,-0.911772113327617,-1.0651934264465188,-0.48722946472103856,2.4847808474675808,0.09554385979269663,0.250123887782108,1.1809557285872447,1.353493558594779 | 3,329 |
Positive regulation of cysteine type endopeptidase activity | 7 | 31 | 2.256505 | 0.024039 | O95831,Q96A26,O75340,Q9NR28,Q9Y3D6,Q01664,Q9BXK5 | Processes and pathways | GO Biological process | msigdb_gobp | 2,196,422,107,408,303,193 | 733,1167,498,422,1930,2,1932,2874,878,1097,1760,2978,1678,2263,1940,1422,1540,2353,303,1543,959,937,196,1002,1823,1400,193,107,1033,792,408 | 0.49606792158741364,0.13442672453612758,0.7903523030093713,0.9342041833231993,-0.26185458923358784,4.947263399328931,-0.26185458923358784,-0.8252617481736726,0.3644259519210431,0.19245224389382748,-0.18124171644076,-0.911772113327617,-0.14119573105890607,-0.4252154935543211,-0.26185458923358784,-0.0023720624187788543,-0.061615792131849874,-0.48722946472103856,1.1983458113760501,-0.061615792131849874,0.30744678607403986,0.3264777895796106,1.640100104496029,0.2692700201272898,-0.20132948448448468,0.01729293365438732,1.656706107741725,2.252714736373069,0.250123887782108,0.4586406374483879,0.9698375183938124 | 3,329 |
Golgi cisterna | 11 | 26 | 2.256034 | 0.024069 | P04439,Q10713,Q99523,P15291,Q9BXS4,Q9H4A6,Q08379,Q9BZG1,Q8NBN3,Q96JB2,O00461 | Localization | GO Cellular component | msigdb_gocc | 468,234,45,457,81,407,501,479,185,441,124 | 124,468,1068,457,1678,645,501,815,502,234,2715,3215,1815,185,665,1552,441,2989,45,81,479,984,407,774,2372,2996 | 2.095042906490493,0.8265153967127852,0.21171518891726354,0.8445465421230678,-0.14119573105890607,0.5890016665615532,0.7903523030093713,0.4210662853564488,0.7903523030093713,1.4725073343753479,-0.697025958957165,-1.3344853226815454,-0.20132948448448468,1.6898359456674157,0.5704867554835045,-0.061615792131849874,0.8805087750259135,-0.911772113327617,2.919261691855399,2.5153331882484165,0.8265153967127852,0.28837759100545446,0.9698375183938124,0.4773725767590705,-0.48722946472103856,-0.911772113327617 | 3,329 |
Myeloid leukocyte activation | 6 | 24 | 2.253951 | 0.024199 | Q92614,P53634,P14174,P15260,Q9NRA0,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 103,73,11,204,53,94 | 1705,1332,857,833,1570,1932,94,2874,343,11,204,3270,1073,73,3155,718,2358,1545,3023,103,2510,576,53,971 | -0.16119720617815728,0.036916819296822626,0.38334347232626,0.40222352433548514,-0.08144731718816471,-0.26185458923358784,2.3151113665623173,-0.8252617481736726,1.1110864980035515,4.033205903886388,1.6068053843688597,-1.5653251277560118,0.21171518891726354,2.576169488318419,-1.1764105997956595,0.5147268428449715,-0.48722946472103856,-0.061615792131849874,-0.9553403143439382,2.283960358788461,-0.570571577370704,0.6810456600510115,2.8011951231396175,0.30744678607403986 | 3,329 |
Threonine type peptidase activity | 6 | 10 | 2.251078 | 0.024381 | P28070,P28074,P28072,Q9UJ14,P49721,P20618 | Functions | GO Molecular function | msigdb_gomf | 3,269,205,309,277,534 | 534,2135,3,205,269,1535,277,2541,653,309 | 0.7358533885259184,-0.3636162385970527,4.700755513120214,1.6068053843688597,1.3363745627961907,-0.061615792131849874,1.3020475866709618,-0.5915261061872295,0.5890016665615532,1.1983458113760501 | 3,329 |
Abnormal thoracic spine morphology | 11 | 30 | 2.250235 | 0.024434 | O95831,P06753,P02545,O43909,Q7RTS9,P08236,P04062,Q9NSE4,Q9UHX1,O00754,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,258,311,392,306,203,84,316,381,150,437 | 3122,150,2696,392,3014,1169,437,2,311,84,258,203,3052,2851,3034,1147,507,1642,2019,2329,2431,306,2920,1025,1868,1558,2275,316,381,1373 | -1.1317574422993255,1.9025645408220684,-0.697025958957165,0.9876055334156724,-0.9553403143439382,0.13442672453612758,0.8805087750259135,4.947263399328931,1.1809557285872447,2.4387828133527267,1.3705830562896129,1.6068053843688597,-0.9991204363631442,-0.8037628442848861,-0.9772037308061117,0.15380820539298756,0.7722200535599743,-0.12123707025353514,-0.30242511290885793,-0.4665116478934158,-0.5288058395850292,1.1983458113760501,-0.8468118326324626,0.250123887782108,-0.2214607347757375,-0.061615792131849874,-0.4252154935543211,1.1809557285872447,1.0230449629802814,0.036916819296822626 | 3,329 |
Flat face | 11 | 25 | 2.237146 | 0.025277 | O75381,P40855,Q9Y487,Q15125,Q96C86,P08236,Q15555,Q9NX62,O00754,O60568,P07437 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 253,383,166,218,526,203,370,672,150,310,533 | 150,1195,310,1008,3014,253,533,203,2702,1603,383,1071,1147,1346,700,2431,218,370,526,2989,2038,672,1305,1138,166 | 1.9025645408220684,0.11500534183447479,1.1809557285872447,0.250123887782108,-0.9553403143439382,1.3876431774355307,0.7358533885259184,1.6068053843688597,-0.697025958957165,-0.10132100472084841,1.0053413016312243,0.21171518891726354,0.15380820539298756,0.036916819296822626,0.5333495101832308,-0.5288058395850292,1.5566548641470208,1.0407166564438557,0.7540537998227098,-0.911772113327617,-0.30242511290885793,0.5704867554835045,0.07604207936374303,0.17314998036516657,1.80493884277799 | 3,329 |
Abnormal epiphyseal ossification | 7 | 17 | 2.232914 | 0.025555 | O75381,P40855,O00116,P38435,Q7RTS9,P08236,Q15125 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 253,383,72,394,306,203,218 | 72,3014,253,203,877,394,383,1147,1250,2431,218,2303,306,405,2989,1630,944 | 2.576169488318419,-0.9553403143439382,1.3876431774355307,1.6068053843688597,0.3644259519210431,0.9876055334156724,1.0053413016312243,0.15380820539298756,0.09554385979269663,-0.5288058395850292,1.5566548641470208,-0.4458404075802983,1.1983458113760501,0.9698375183938124,-0.911772113327617,-0.10132100472084841,0.3264777895796106 | 3,329 |
Aurka activation by tpx2 | 13 | 37 | 2.224516 | 0.026114 | Q68CZ6,O94927,Q13561,O95684,Q9NVX0,Q15691,P41208,Q9H6D7,O43805,Q96CS2,O95613,P07437,O75935 | Processes and pathways | Reactome Pathways | msigdb_reactome | 352,129,321,263,589,328,326,17,428,249,622,533,283 | 428,876,283,129,622,263,779,1414,533,2211,2910,1800,1176,326,2325,1491,1492,1539,1049,1540,1017,1499,321,3088,883,3199,979,328,352,2360,1431,249,704,2118,17,589,1965 | 0.8984401573767984,0.3644259519210431,1.2848393592155545,2.0312870262355047,0.6074809899769386,1.353493558594779,0.4586406374483879,-0.0023720624187788543,0.7358533885259184,-0.40463665770934043,-0.8468118326324626,-0.20132948448448468,0.13442672453612758,1.1460831559915547,-0.4665116478934158,-0.04182621575808879,-0.04182621575808879,-0.061615792131849874,0.2309390068867304,-0.061615792131849874,0.250123887782108,-0.04182621575808879,1.1635348870399604,-1.043114967374901,0.3644259519210431,-1.2890331559905834,0.28837759100545446,1.1460831559915547,1.093541305136819,-0.48722946472103856,-0.0023720624187788543,1.4046740427964144,0.5333495101832308,-0.34317416950457963,3.7109265553036352,0.6627070637091839,-0.26185458923358784 | 3,329 |
Mental deterioration | 31 | 103 | 2.220993 | 0.026351 | O75503,P61916,O43681,Q5XKP0,Q14108,P50897,P20700,P09651,P07602,Q9Y487,P22626,P54802,P06865,O15118,P17900,Q13148,P07686,P21964,P00846,Q9NQ11,Q13510,P04062,P16278,Q7LG56,P35637,O95470,O60220,Q10713,P43243,O95140,O76024 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 14,142,391,402,23,27,287,410,37,166,167,42,48,183,56,439,191,320,71,199,82,84,89,219,90,466,227,234,488,235,486 | 1706,183,391,1523,227,1038,2344,807,14,486,235,466,1043,499,71,2090,84,1450,779,48,37,191,3068,1892,410,2587,877,89,1455,56,3052,287,2012,320,167,3249,1382,1312,90,1070,2214,2349,1014,488,3070,27,3139,2098,42,1681,2263,1315,142,1539,3001,1346,717,2428,1208,598,1942,234,2801,439,625,82,23,883,2358,1079,402,3060,2359,821,219,3046,2363,2308,2891,3267,1823,1258,3157,2892,2946,2310,2831,1826,2921,690,199,588,1963,2694,1330,1033,1520,3048,2991,946,1137,2901,166 | -0.16119720617815728,1.6898359456674157,0.9876055334156724,-0.061615792131849874,1.5062515283479845,0.2309390068867304,-0.48722946472103856,0.4210662853564488,3.9801481206823643,0.808450700356778,1.4555923000904791,0.8265153967127852,0.2309390068867304,0.7903523030093713,2.606454697302084,-0.34317416950457963,2.4387828133527267,-0.022078375983966562,0.4586406374483879,2.889869040112362,3.079474577048757,1.656706107741725,-1.0210907434410021,-0.2416356936301747,0.952037115657918,-0.633579801148074,0.3644259519210431,2.3771322660471457,-0.022078375983966562,2.771469962197346,-0.9991204363631442,1.2676011393842441,-0.30242511290885793,1.1635348870399604,1.788575826344145,-1.4491487014145832,0.01729293365438732,0.056499799932090956,2.361661969696948,0.21171518891726354,-0.40463665770934043,-0.48722946472103856,0.250123887782108,0.808450700356778,-1.0210907434410021,3.35063652301562,-1.1540560850036303,-0.34317416950457963,2.992386889912926,-0.14119573105890607,-0.4252154935543211,0.056499799932090956,1.934898419838436,-0.061615792131849874,-0.9335298774233274,0.036916819296822626,0.5147268428449715,-0.5288058395850292,0.11500534183447479,0.6443335267862096,-0.26185458923358784,1.4725073343753479,-0.7609174191294885,0.8805087750259135,0.6074809899769386,2.4847808474675808,3.5875674867137177,0.3644259519210431,-0.48722946472103856,0.21171518891726354,0.9698375183938124,-0.9991204363631442,-0.48722946472103856,0.4210662853564488,1.539881993567282,-0.9772037308061117,-0.48722946472103856,-0.4458404075802983,-0.8252617481736726,-1.5419664934801736,-0.20132948448448468,0.09554385979269663,-1.1764105997956595,-0.8252617481736726,-0.868413390715352,-0.4458404075802983,-0.7823148305441647,-0.20132948448448468,-0.8468118326324626,0.5519360920063213,1.6234665666051777,0.6627070637091839,-0.26185458923358784,-0.6758281295241295,0.056499799932090956,0.250123887782108,-0.04182621575808879,-0.9772037308061117,-0.911772113327617,0.3264777895796106,0.17314998036516657,-0.8252617481736726,1.80493884277799 | 3,329 |
Cation transmembrane transporter activity | 27 | 65 | 2.218058 | 0.026551 | Q9H2J7,P12235,P47985,P56385,P20674,P08195,P06576,Q9Y487,O14548,O43772,Q70HW3,O75947,P13073,P16615,Q9HD20,Q9NQ11,P00846,Q9Y619,Q9HC07,Q9UDW1,Q8N4V1,Q9Y5K8,Q7KZN9,O75964,P00403,Q93050,Q96QD8 | Functions | GO Molecular function | msigdb_gomf | 260,763,384,642,517,780,795,166,793,170,46,677,680,696,70,199,71,79,220,221,354,635,745,112,499,120,511 | 793,170,1374,677,112,3188,1064,499,71,1044,1065,2210,795,1529,2253,780,1415,1095,763,680,696,1757,517,2257,3223,902,2704,1671,903,1070,2214,384,2668,1101,1016,1457,642,1683,2354,1345,1580,1727,46,745,354,1507,890,3141,120,1359,1869,511,2514,260,828,1220,220,70,199,221,1134,1305,166,635,79 | 0.43987193147095827,1.7557699570002447,0.01729293365438732,0.5519360920063213,2.2213738074871006,-1.2663941639873593,0.21171518891726354,0.7903523030093713,2.606454697302084,0.2309390068867304,0.21171518891726354,-0.40463665770934043,0.43987193147095827,-0.061615792131849874,-0.4252154935543211,0.4586406374483879,-0.0023720624187788543,0.19245224389382748,0.4773725767590705,0.5519360920063213,0.5333495101832308,-0.18124171644076,0.7540537998227098,-0.4252154935543211,-1.3572992144054614,0.34547078437245365,-0.697025958957165,-0.14119573105890607,0.34547078437245365,0.21171518891726354,-0.40463665770934043,1.0053413016312243,-0.6758281295241295,0.19245224389382748,0.250123887782108,-0.022078375983966562,0.5890016665615532,-0.14119573105890607,-0.48722946472103856,0.036916819296822626,-0.08144731718816471,-0.16119720617815728,2.9045756177690114,0.49606792158741364,1.093541305136819,-0.04182621575808879,0.3644259519210431,-1.1540560850036303,2.126772142320419,0.036916819296822626,-0.2214607347757375,0.7722200535599743,-0.570571577370704,1.3705830562896129,0.4210662853564488,0.11500534183447479,1.539881993567282,2.6215643365115513,1.6234665666051777,1.539881993567282,0.17314998036516657,0.07604207936374303,1.80493884277799,0.6074809899769386,2.530575692978956 | 3,329 |
Generalized muscle weakness | 10 | 36 | 2.216524 | 0.026656 | P09651,O95831,Q92804,P06753,Q9NQ11,Q15165,P10253,P35637,Q13148,P11047 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 410,2,68,258,199,74,109,90,439,319 | 3031,2,258,2555,410,109,319,763,2012,3180,1382,90,2527,1014,488,1895,1456,2454,2263,2530,1642,439,625,883,2393,74,1079,68,2310,2160,607,199,2991,946,2901,874 | -0.9772037308061117,4.947263399328931,1.3705830562896129,-0.6125287588483042,0.952037115657918,2.2370562287908466,1.1635348870399604,0.4773725767590705,-0.30242511290885793,-1.2438127606249867,0.01729293365438732,2.361661969696948,-0.5915261061872295,0.250123887782108,0.808450700356778,-0.2416356936301747,-0.022078375983966562,-0.5496649089080891,-0.4252154935543211,-0.5915261061872295,-0.12123707025353514,0.8805087750259135,0.6074809899769386,0.3644259519210431,-0.5079941104366322,2.560993764910525,0.21171518891726354,2.651718065289016,-0.4458404075802983,-0.3636162385970527,0.6443335267862096,1.6234665666051777,-0.911772113327617,0.3264777895796106,-0.8252617481736726,0.38334347232626 | 3,329 |
Sensory neuropathy | 9 | 39 | 2.215552 | 0.026722 | O95831,Q15067,P22626,Q9NQ11,P00846,O60220,Q8IV08,Q15041,O95140 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,39,167,199,71,227,13,174,235 | 637,1196,227,2206,1038,735,235,2,499,71,2090,2617,410,2619,167,3249,681,2527,1717,1100,2263,2530,3127,1806,174,39,961,1766,13,3184,2110,585,3157,2892,1875,199,316,3161,874 | 0.5890016665615532,0.11500534183447479,1.5062515283479845,-0.40463665770934043,0.2309390068867304,0.49606792158741364,1.4555923000904791,4.947263399328931,0.7903523030093713,2.606454697302084,-0.34317416950457963,-0.6546795012118433,0.952037115657918,-0.6546795012118433,1.788575826344145,-1.4491487014145832,0.5519360920063213,-0.5915261061872295,-0.16119720617815728,0.19245224389382748,-0.4252154935543211,-0.5915261061872295,-1.1317574422993255,-0.20132948448448468,1.7393268960087505,3.0360202880874745,0.30744678607403986,-0.18124171644076,4.0067090850261815,-1.2438127606249867,-0.34317416950457963,0.6627070637091839,-1.1764105997956595,-0.8252617481736726,-0.2214607347757375,1.6234665666051777,1.1809557285872447,-1.198821323451637,0.38334347232626 | 3,329 |
Abnormal brainstem mri signal intensity | 11 | 24 | 2.213787 | 0.026843 | O95831,O43676,Q969Y2,O75380,Q9Y6M9,O75489,O96000,Q8N183,Q8IUX1,Q96CU9,Q86Y39 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,189,617,382,202,638,393,584,307,280,380 | 1660,189,2906,807,382,638,2,393,2452,3166,1895,2915,1315,380,307,584,1991,617,280,1826,690,1058,943,202 | -0.14119573105890607,1.656706107741725,-0.8468118326324626,0.4210662853564488,1.0053413016312243,0.5890016665615532,4.947263399328931,0.9876055334156724,-0.5496649089080891,-1.2212885959722362,-0.2416356936301747,-0.8468118326324626,0.056499799932090956,1.0230449629802814,1.1983458113760501,0.6627070637091839,-0.2821176516631388,0.6259248892678739,1.3020475866709618,-0.20132948448448468,0.5519360920063213,0.2309390068867304,0.3264777895796106,1.6234665666051777 | 3,329 |
Developmental maturation | 8 | 40 | 2.212423 | 0.026937 | Q9Y5A9,P07196,Q9Y2W6,O75503,P04062,Q9UJX6,Q08J23,Q15125 | Processes and pathways | GO Biological process | msigdb_gobp | 261,130,41,14,84,246,22,218 | 3131,2952,1844,2410,14,1412,273,84,1413,130,2555,2174,1337,2483,2910,3052,1800,1417,2350,2384,2098,1101,1940,1494,22,3213,1724,434,218,2715,1987,2464,2918,1866,3245,753,1033,246,41,261 | -1.1540560850036303,-0.890066718141344,-0.2214607347757375,-0.5288058395850292,3.9801481206823643,-0.0023720624187788543,1.3192259465409601,2.4387828133527267,-0.0023720624187788543,2.0312870262355047,-0.6125287588483042,-0.3841036540358946,0.036916819296822626,-0.570571577370704,-0.8468118326324626,-0.9991204363631442,-0.20132948448448468,-0.0023720624187788543,-0.48722946472103856,-0.5079941104366322,-0.34317416950457963,0.19245224389382748,-0.26185458923358784,-0.04182621575808879,3.5875674867137177,-1.3344853226815454,-0.16119720617815728,0.8984401573767984,1.5566548641470208,-0.697025958957165,-0.2821176516631388,-0.5496649089080891,-0.8468118326324626,-0.2214607347757375,-1.426096499582426,0.49606792158741364,0.250123887782108,1.4216757723522286,3.0069513662975234,1.3705830562896129 | 3,329 |
mRNA splicing factor | 32 | 63 | 3.74684 | 0.000179 | Q12874,Q93062,Q13595,Q01130,Q08170,O95391,Q01844,O75934,P08621,P98179,Q92804,Q96PK6,Q15287,Q9BWF3,O75525,P23246,Q8WWY3,Q15428,Q14011,Q13243,Q07666,Q8IWZ8,P35637,P62995,P38159,Q13247,Q8IY67,Q07955,Q13242,Q96PU8,P62312,Q16629 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 500,269,265,264,646,144,276,26,534,42,44,432,176,447,186,565,595,339,82,222,347,611,105,106,114,239,632,119,120,247,125,245 | 3207,2871,1148,1446,1149,186,1732,26,1554,144,2391,534,2340,2023,2026,565,760,105,114,2187,125,3194,2708,106,876,42,264,276,347,119,646,1326,2512,500,120,222,239,265,82,2149,819,176,3107,339,1875,976,245,2576,1477,611,2209,632,595,1028,44,269,432,247,447,680,1272,2004,2891 | -1.3189932645559714,-0.7926651659142298,0.15153676993565662,-0.029865285809226125,0.15153676993565662,1.6049137736549657,-0.16158973914559305,3.696414649480699,-0.08233536597590257,1.8245401660987595,-0.4854742296273154,0.7246943926167733,-0.4580496538163419,-0.295180369866429,-0.295180369866429,0.6761640336993322,0.45477069366704176,2.1456239302772926,2.060946771039656,-0.3762589684803563,1.9755904513220965,-1.2889217482537252,-0.6517555885208118,2.1456239302772926,0.3547430731572368,2.9969079945886623,1.2894112075322974,1.2665002131565157,1.0579461872044702,1.9969939624566933,0.5783821220634734,0.04830079543718118,-0.5405685646734597,0.7729883317782116,1.9969939624566933,1.4483695677566368,1.3805456873453574,1.2894112075322974,2.3337340456373328,-0.3491544285666504,0.4048853041523916,1.6492101744410923,-1.081235302599538,1.0813318676981678,-0.21479828637447215,0.27904070667935305,1.3350797695503047,-0.5682395708805944,-0.029865285809226125,0.627394286483852,-0.3762589684803563,0.6029186981351422,0.6518092715010478,0.2536744416950175,2.918617137277597,1.2894112075322974,0.8927077987407493,1.3350797695503047,0.8688785329912848,0.5537841699438737,0.10005794963749391,-0.26830970462499465,-0.7926651659142298 | 3,329 |
Protein localization | 40 | 72 | 3.601002 | 0.000317 | Q9NX63,Q15388,Q3ZCQ8,O14925,Q9NS69,O43615,Q9NR77,Q99595,P12235,Q9BTZ2,O75381,Q9Y3D6,O43681,P40855,Q9Y512,O96008,P50402,P21796,P46379,O43765,O15228,O60220,P35914,Q8TB36,Q5JRX3,Q10713,Q7L5D6,Q5T8D3,P09601,Q13505,O14734,Q9Y5J7,Q9Y5J9,P51648,Q9BY49,Q13011,Q15067,O43808,O75431,Q8N4H5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 661,130,392,513,20,777,28,29,535,163,662,436,302,305,708,809,442,188,690,562,437,438,813,852,457,326,849,846,84,87,837,365,366,363,383,117,378,621,368,127 | 836,837,513,437,777,302,562,621,438,662,2639,368,1961,1963,1243,960,1244,809,869,1365,3091,84,3012,535,2179,1623,188,904,2557,2458,1250,813,2931,305,690,442,1413,1126,363,1414,1374,326,117,87,378,130,392,457,846,849,127,982,1334,852,3108,29,2217,163,383,1888,28,20,661,927,2376,999,3162,1194,436,708,365,366 | 0.37984650423133043,0.37984650423133043,0.7488707314457396,0.8688785329912848,0.4298598948054332,1.1511662908811733,0.6761640336993322,0.6029186981351422,0.8688785329912848,0.5537841699438737,-0.6238324359129747,0.9874620606273097,-0.26830970462499465,-0.26830970462499465,0.10005794963749391,0.27904070667935305,0.10005794963749391,0.4048853041523916,0.3547430731572368,0.022316639316524726,-1.0519576968380968,2.312994690116114,-0.9357946539309187,0.7246943926167733,-0.3762589684803563,-0.10867973722712838,1.5826946039902199,0.3295745845722661,-0.5682395708805944,-0.5129803266852947,0.10005794963749391,0.4048853041523916,-0.8496455939132849,1.1511662908811733,0.5291244494621641,0.8688785329912848,-0.0037385556102236188,0.1771729889257694,1.0110116072884079,-0.0037385556102236188,0.022316639316524726,1.1046635682791401,2.0183543729266775,2.292215357083478,0.9874620606273097,1.9111190840245948,0.9638572394951759,0.8449923030501421,0.37984650423133043,0.37984650423133043,1.9541436174566913,0.27904070667935305,0.04830079543718118,0.37984650423133043,-1.081235302599538,3.418002954518594,-0.3762589684803563,1.715303744000135,0.9874620606273097,-0.21479828637447215,3.4555183288603515,3.824070221368311,0.5783821220634734,0.3295745845722661,-0.4580496538163419,0.27904070667935305,-1.1696493065603792,0.15153676993565662,0.8927077987407493,0.5291244494621641,1.0110116072884079,1.0110116072884079 | 3,329 |
Tetrapyrrole binding | 9 | 17 | 3.571094 | 0.000355 | Q8WUJ1,O43169,Q9NRV9,O15173,Q16850,P30519,P53701,P09601,P22033 | Functions | GO Molecular function | msigdb_gomf | 0,103,8,73,76,13,111,84,58 | 361,73,103,1365,84,58,13,111,76,229,1878,0,2214,1593,1396,1073,8 | 1.0110116072884079,2.3957141915052134,2.166688703312481,0.022316639316524726,2.312994690116114,2.5795576219558023,4.233929790975661,2.0821791937785017,2.3957141915052134,1.4258112341953242,-0.21479828637447215,6.409950471125959,-0.3762589684803563,-0.08233536597590257,0.022316639316524726,0.2282413677095567,4.510881361292507 | 3,329 |
Regulation of mrna splicing via spliceosome | 34 | 68 | 3.561896 | 0.000368 | P61978,P22626,Q13595,Q01130,P51116,Q08170,P08621,Q9UHX1,Q92841,P17844,P98179,Q96SB4,Q15287,Q9Y2W1,P98175,Q9BWF3,O75525,P51114,Q8IYB3,P09651,Q14011,Q8NDT2,Q07666,Q15007,Q07021,P62995,P38159,Q9Y5S9,Q13247,Q8IY67,Q13242,Q96PU8,Q16629,P78362 | Processes and pathways | GO Biological process | msigdb_gobp | 129,134,265,264,517,646,534,686,551,665,42,698,176,707,307,447,186,691,316,313,82,478,347,223,98,106,114,640,239,632,120,247,245,627 | 1357,1149,186,534,313,2242,714,665,1798,2026,134,905,1919,2876,1454,114,2139,691,517,1515,1321,1054,129,106,627,876,307,42,2190,264,817,98,347,646,1326,2512,120,239,1170,265,82,1295,223,176,766,976,245,2100,3023,2913,3275,632,316,478,551,1430,1887,990,247,698,3202,2433,447,3064,686,1115,707,640 | 0.022316639316524726,0.15153676993565662,1.6049137736549657,0.7246943926167733,1.1279416049827429,-0.4034426244745279,0.5044025642582864,0.5537841699438737,-0.18815642658314627,-0.295180369866429,1.8895409310176001,0.3295745845722661,-0.24151586233357789,-0.7926651659142298,-0.029865285809226125,2.060946771039656,-0.3491544285666504,0.5291244494621641,0.7488707314457396,-0.056064053346613754,0.04830079543718118,0.2282413677095567,1.9111190840245948,2.1456239302772926,0.6029186981351422,0.3547430731572368,1.1511662908811733,2.9969079945886623,-0.3762589684803563,1.2894112075322974,0.4048853041523916,2.2296355176645477,1.0579461872044702,0.5783821220634734,0.04830079543718118,-0.5405685646734597,1.9969939624566933,1.3805456873453574,0.15153676993565662,1.2894112075322974,2.3337340456373328,0.07421440370362554,1.4483695677566368,1.6492101744410923,0.45477069366704176,0.27904070667935305,1.3350797695503047,-0.32212842123349283,-0.9357946539309187,-0.8211106352670356,-1.8148106953273693,0.6029186981351422,1.1279416049827429,0.8210487610060045,0.7004589497661892,-0.0037385556102236188,-0.21479828637447215,0.27904070667935305,1.3350797695503047,0.5291244494621641,-1.2889217482537252,-0.4854742296273154,0.8688785329912848,-0.9936882624211686,0.5537841699438737,0.2027410349919575,0.5291244494621641,0.6029186981351422 | 3,329 |
mRNA processing factor | 34 | 78 | 3.540454 | 0.000399 | Q12874,Q93062,Q13595,Q01130,Q08170,O95391,Q01844,O75934,P08621,P98179,Q92804,Q96PK6,Q15287,Q9BWF3,O75525,P23246,Q8IYB3,Q8WWY3,Q15428,Q14011,Q13243,Q07666,Q8IWZ8,P35637,P62995,Q16629,P38159,Q13247,Q8IY67,Q07955,Q13242,Q96PU8,P62312,P51003 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 500,269,265,264,646,144,276,26,534,42,44,432,176,447,186,565,316,595,339,82,222,347,611,105,106,245,114,239,632,119,120,247,125,124 | 1359,3207,2871,1148,1446,1149,186,1732,26,1554,1363,144,808,2391,534,2340,2023,2026,565,760,105,114,124,3237,2187,125,3194,2188,2708,106,876,42,264,276,347,119,646,1326,2713,2512,500,1058,1869,120,222,239,265,82,2149,819,176,3107,339,1875,976,1064,245,2576,1477,611,2209,632,316,595,1028,44,269,2885,918,1714,432,247,1529,447,680,1272,2004,2891 | 0.022316639316524726,-1.3189932645559714,-0.7926651659142298,0.15153676993565662,-0.029865285809226125,0.15153676993565662,1.6049137736549657,-0.16158973914559305,3.696414649480699,-0.08233536597590257,0.022316639316524726,1.8245401660987595,0.4048853041523916,-0.4854742296273154,0.7246943926167733,-0.4580496538163419,-0.295180369866429,-0.295180369866429,0.6761640336993322,0.45477069366704176,2.1456239302772926,2.060946771039656,1.9755904513220965,-1.440319734225996,-0.3762589684803563,1.9755904513220965,-1.2889217482537252,-0.3762589684803563,-0.6517555885208118,2.1456239302772926,0.3547430731572368,2.9969079945886623,1.2894112075322974,1.2665002131565157,1.0579461872044702,1.9969939624566933,0.5783821220634734,0.04830079543718118,-0.6517555885208118,-0.5405685646734597,0.7729883317782116,0.2282413677095567,-0.21479828637447215,1.9969939624566933,1.4483695677566368,1.3805456873453574,1.2894112075322974,2.3337340456373328,-0.3491544285666504,0.4048853041523916,1.6492101744410923,-1.081235302599538,1.0813318676981678,-0.21479828637447215,0.27904070667935305,0.2282413677095567,1.3350797695503047,-0.5682395708805944,-0.029865285809226125,0.627394286483852,-0.3762589684803563,0.6029186981351422,1.1279416049827429,0.6518092715010478,0.2536744416950175,2.918617137277597,1.2894112075322974,-0.7926651659142298,0.3295745845722661,-0.1350976864977832,0.8927077987407493,1.3350797695503047,-0.056064053346613754,0.8688785329912848,0.5537841699438737,0.10005794963749391,-0.26830970462499465,-0.7926651659142298 | 3,329 |
Alternative mrna splicing via spliceosome | 27 | 44 | 3.518157 | 0.000435 | P51116,Q01130,O95391,Q9UHX1,O60828,Q92841,P17844,Q15287,Q9Y2W1,P98175,Q9BWF3,O75525,P51114,P23246,P52272,P09651,P14866,Q8NDT2,Q07666,Q15007,P62995,P38159,Q9Y5S9,Q13247,Q8IY67,Q07955,Q13242 | Processes and pathways | GO Biological process | msigdb_gobp | 517,264,144,686,531,551,665,176,707,307,447,186,691,565,314,313,714,478,347,223,106,114,640,239,632,119,120 | 1357,710,531,186,144,313,714,665,565,1919,1454,114,2139,691,517,1515,314,1321,106,307,2190,264,817,347,119,1521,2512,120,239,223,176,2100,632,478,551,1430,918,990,3202,447,686,707,1899,640 | 0.022316639316524726,0.5044025642582864,0.7246943926167733,1.6049137736549657,1.8245401660987595,1.1279416049827429,0.5044025642582864,0.5537841699438737,0.6761640336993322,-0.24151586233357789,-0.029865285809226125,2.060946771039656,-0.3491544285666504,0.5291244494621641,0.7488707314457396,-0.056064053346613754,1.1279416049827429,0.04830079543718118,2.1456239302772926,1.1511662908811733,-0.3762589684803563,1.2894112075322974,0.4048853041523916,1.0579461872044702,1.9969939624566933,-0.056064053346613754,-0.5405685646734597,1.9969939624566933,1.3805456873453574,1.4483695677566368,1.6492101744410923,-0.32212842123349283,0.6029186981351422,0.8210487610060045,0.7004589497661892,-0.0037385556102236188,0.3295745845722661,0.27904070667935305,-1.2889217482537252,0.8688785329912848,0.5537841699438737,0.5291244494621641,-0.21479828637447215,0.6029186981351422 | 3,329 |
Regulation of rna splicing | 44 | 92 | 3.511194 | 0.000446 | P61978,P22626,Q13595,P51116,P49736,Q08170,Q01130,O75312,P55795,P08621,Q9UHX1,O60828,Q92841,P17844,P98179,Q96SB4,Q15287,Q9Y2W1,P98175,Q9BWF3,O75525,Q8IYB3,P09651,Q5BKZ1,Q14011,Q8NDT2,P52597,Q13243,Q07666,P31943,Q15007,Q07021,P35637,P62995,P38159,Q9Y5S9,Q13247,Q8IY67,P31942,Q07955,Q13242,Q96PU8,Q16629,P78362 | Processes and pathways | GO Biological process | msigdb_gobp | 129,134,265,517,516,646,264,17,151,534,686,531,551,665,42,698,176,707,307,447,186,316,313,340,82,478,89,222,347,94,223,98,105,106,114,640,239,632,118,119,120,247,245,627 | 1357,531,17,1149,186,534,313,2242,714,665,1798,2026,134,1560,905,1919,2876,1454,118,94,105,114,516,2139,691,517,1515,89,1321,1054,151,129,2707,2295,106,627,876,307,42,2190,264,817,98,347,119,646,1326,2750,1210,2512,120,222,239,1170,265,82,1983,1295,1261,223,176,766,976,245,2100,3023,340,2913,3275,785,632,316,478,787,551,1430,1887,990,247,1394,698,3202,2433,447,3064,1652,3277,686,1952,1115,707,640 | 0.022316639316524726,0.7246943926167733,4.039697600119232,0.15153676993565662,1.6049137736549657,0.7246943926167733,1.1279416049827429,-0.4034426244745279,0.5044025642582864,0.5537841699438737,-0.18815642658314627,-0.295180369866429,1.8895409310176001,-0.08233536597590257,0.3295745845722661,-0.24151586233357789,-0.7926651659142298,-0.029865285809226125,1.9969939624566933,2.2505359699505556,2.1456239302772926,2.060946771039656,0.7488707314457396,-0.3491544285666504,0.5291244494621641,0.7488707314457396,-0.056064053346613754,2.2713958497962627,0.04830079543718118,0.2282413677095567,1.7809820616407097,1.9111190840245948,-0.6517555885208118,-0.43070598704832075,2.1456239302772926,0.6029186981351422,0.3547430731572368,1.1511662908811733,2.9969079945886623,-0.3762589684803563,1.2894112075322974,0.4048853041523916,2.2296355176645477,1.0579461872044702,1.9969939624566933,0.5783821220634734,0.04830079543718118,-0.6797640971855716,0.12583191341257804,-0.5405685646734597,1.9969939624566933,1.4483695677566368,1.3805456873453574,0.15153676993565662,1.2894112075322974,2.3337340456373328,-0.26830970462499465,0.07421440370362554,0.10005794963749391,1.4483695677566368,1.6492101744410923,0.45477069366704176,0.27904070667935305,1.3350797695503047,-0.32212842123349283,-0.9357946539309187,1.0813318676981678,-0.8211106352670356,-1.8148106953273693,0.4298598948054332,0.6029186981351422,1.1279416049827429,0.8210487610060045,0.4298598948054332,0.7004589497661892,-0.0037385556102236188,-0.21479828637447215,0.27904070667935305,1.3350797695503047,0.022316639316524726,0.5291244494621641,-1.2889217482537252,-0.4854742296273154,0.8688785329912848,-0.9936882624211686,-0.10867973722712838,-1.8148106953273693,0.5537841699438737,-0.24151586233357789,0.2027410349919575,0.5291244494621641,0.6029186981351422 | 3,329 |
Negative regulation of mrna metabolic process | 17 | 47 | 3.342398 | 0.000831 | P61978,Q13148,Q07021,P22626,P35637,O60506,Q92804,Q15287,P16989,P98175,Q14011,P38159,Q13247,P67809,Q99729,Q13242,Q16629 | Processes and pathways | GO Biological process | msigdb_gobp | 129,413,98,134,105,259,44,176,80,307,82,114,239,86,382,120,245 | 2953,931,1357,259,440,1149,1448,586,2024,80,1366,134,905,1919,105,114,129,86,307,2190,817,98,646,1521,2512,413,1870,120,239,82,518,176,767,1467,245,1066,1472,1700,1818,3275,1646,44,382,2433,856,1439,707 | -0.8782707619883378,0.3043406075801465,0.022316639316524726,1.2894112075322974,0.8688785329912848,0.15153676993565662,-0.029865285809226125,0.6518092715010478,-0.295180369866429,2.354433618846386,0.022316639316524726,1.8895409310176001,0.3295745845722661,-0.24151586233357789,2.1456239302772926,2.060946771039656,1.9111190840245948,2.292215357083478,1.1511662908811733,-0.3762589684803563,0.4048853041523916,2.2296355176645477,0.5783821220634734,-0.056064053346613754,-0.5405685646734597,0.9164804448280517,-0.21479828637447215,1.9969939624566933,1.3805456873453574,2.3337340456373328,0.7488707314457396,1.6492101744410923,0.45477069366704176,-0.029865285809226125,1.3350797695503047,0.2282413677095567,-0.029865285809226125,-0.1350976864977832,-0.18815642658314627,-1.8148106953273693,-0.10867973722712838,2.918617137277597,0.9874620606273097,-0.4854742296273154,0.37984650423133043,-0.0037385556102236188,0.5291244494621641 | 3,329 |
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