term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Optic disc pallor | 23 | 48 | 3.426666 | 0.000611 | O96000,Q6P4Q7,O43676,Q8IUX1,P00846,Q9Y6M9,O95140,Q96CU9,Q9H061,Q9NX14,Q9Y4W6,Q9H0B6,Q9BUK6,Q86Y39,O75306,Q9UG56,O60313,P04439,P03886,O95831,Q10713,Q9NPL8,Q96S66 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,263,8,135,14,37,546,44,45,441,577,452,584,77,339,344,219,475,95,359,233,240,253 | 807,1071,1175,1199,8,1322,219,839,339,2285,1297,2093,546,359,129,14,95,475,2306,1279,1825,2531,2765,1707,2919,2839,1448,233,1224,263,77,135,1789,1049,1791,44,253,584,45,452,240,441,1137,344,1018,596,577,37 | 0.3223889389369212,0.09898651295405862,0.034056888274781295,0.020912454144430923,3.0713505910312833,-0.05909615052808124,1.5813953757113124,0.28622861567613295,1.2295800256388367,-0.6168313523355917,-0.04562344444480704,-0.4913854476709634,0.7475317096601524,1.1756765413677428,1.9850015170325637,3.0256480119669416,2.1700017598173678,0.8904664767159661,-0.6328456266009942,-0.032206450409452865,-0.3409143906622731,-0.7972875946120856,-1.1705743485850078,-0.26816160686466817,-2.2328711809732935,-1.4032600540214297,-0.12730986022355953,1.5175956622312197,0.007714294292187978,1.4274982699452592,2.343244888252367,1.9506190541438213,-0.31162085873717893,0.12459546086867959,-0.31162085873717893,2.643303939387849,1.4523500544317842,0.6841640874618475,2.6379469928697454,0.9399248957090145,1.4933010900118375,0.9692152220740943,0.07317166718379643,1.2206642044639127,0.15000139369493218,0.662747577217144,0.705432417367614,2.7015163290761643 | 2,948 |
Nonalcoholic fatty liver disease | 12 | 49 | 3.4217 | 0.000622 | O96000,O14949,Q9Y6M9,P14406,O43676,Q86Y39,P00403,P22695,Q9UDW1,Q9P0J0,P13073,P21912 | Processes and pathways | WikiPathways | msigdb_wp | 129,33,37,7,8,77,60,109,50,86,155,188 | 1000,448,1019,33,8,839,339,1297,2095,2335,2542,129,60,1928,809,1039,686,155,7,633,932,1825,601,188,109,2531,1301,612,1441,963,858,1802,2765,1559,1732,803,1285,975,2494,1655,570,1373,1223,77,221,441,86,50,37 | 0.15000139369493218,0.9399248957090145,0.13732362625944375,2.737894239182016,3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.5059894136062666,-0.40028941407932933,0.3223889389369212,0.12459546086867959,0.48585396547881715,1.8663245911664819,3.1028556423025955,0.5755625753080114,0.2126464378878266,-0.3409143906622731,0.6411810535042607,1.6897313558966025,2.059171659276056,-0.7972875946120856,-0.04562344444480704,0.6194626505037427,-0.12730986022355953,0.18773580450914448,0.27408278382771123,-0.3262352210800657,-1.1705743485850078,-0.18292663566061074,-0.2825845468972897,0.33435101991744987,-0.032206450409452865,0.17520713667950955,-0.7637577132524961,-0.23950372309971943,0.7160115787906041,-0.08621034266007742,0.007714294292187978,2.343244888252367,1.5813953757113124,0.9692152220740943,2.258009524162855,2.6001384504964156,2.7015163290761643 | 2,948 |
Organelle inner membrane | 137 | 243 | 3.39645 | 0.000683 | Q9UDX5,P14406,O43676,Q96IX5,Q99595,P00846,Q99720,Q69YU5,Q9H1E5,P53007,Q53H12,Q9Y584,Q9H2D1,O14949,Q9Y6M9,O75844,Q96CU9,Q9H061,O60830,Q9UDW1,Q8NI60,O43772,Q9UBX3,Q15070,P00403,Q9Y4W6,Q9Y2R0,P06576,Q70HW3,Q9BYC9,Q9UH99,O43819,Q86Y39,Q9Y375,Q9BUR5,Q9P0J0,Q9NX63,P82933,O75964,Q6P4A7,P20674,P03886,P62995,P56134,O14925,Q9BYN8,P22695,Q9H936,Q8IXM6,Q709F0,Q9BRT2,Q14739,Q96BW9,Q13505,P22830,P14927,P18031,O96000,Q9UJS0,Q9BQ95,Q9Y619,Q9Y2U8,Q8IUX1,O95202,Q9H300,P12236,P13073,Q96ER9,Q9NQ50,Q13423,P43243,Q7KZN9,P20700,P10606,O96008,Q9H3K2,P21912,P50402,Q9Y6C9,Q9Y5J7,O94901,Q5HYI7,O60313,O75431,Q9HC21,Q8NBN7,P24539,P23786,Q10713,Q99623,Q9NPL8,Q7Z7H8,Q9Y5L4,Q5SNT2,Q9BQT8,Q7Z7F7,Q5XKP0,Q5T9A4,O75880,O43615,P53701,P62072,Q9Y5J9,P05141,O60220,Q96E52,Q6UXV4,Q9Y512,P56385,Q6NUK1,Q9NVH1,Q9NVI7,Q6DKK2,Q9H9B4,O75306,Q9UG56,Q9BRJ2,O95831,Q96NB2,Q16891,O75027,O75208,Q6PI78,Q02978,P40939,Q8NE86,P12235,Q9NX14,Q00325,O14548,O75746,Q9H2V7,Q3ZCQ8,Q9BUB7,Q96AQ8,P35232,Q16134 | Localization | GO Cellular component | msigdb_gocc | 3,7,8,520,10,14,21,22,23,530,539,28,31,33,37,43,44,45,49,50,558,567,57,59,60,577,61,572,66,580,586,582,77,596,81,86,599,604,88,91,601,95,603,615,108,621,109,622,112,628,630,118,638,123,635,633,641,129,652,650,136,653,135,138,152,154,155,679,683,170,674,174,687,686,685,179,188,195,197,196,198,215,219,223,225,227,231,232,233,238,240,246,254,258,268,272,279,284,288,287,289,294,298,303,302,307,313,318,312,320,321,322,330,336,339,344,357,359,372,370,374,381,414,420,426,427,433,441,440,448,456,467,470,478,491,486,508 | 1000,448,108,33,287,8,567,582,302,219,721,49,374,381,839,339,774,223,2285,1297,896,988,456,43,288,1774,88,1525,198,2095,2335,138,2542,359,129,685,60,14,95,2112,303,572,2610,809,2837,1464,1039,686,1960,1555,433,154,2509,155,7,633,932,641,810,1825,601,687,188,2612,109,635,1501,232,231,1439,2531,1301,1441,1080,486,900,901,2543,426,1849,674,916,858,2459,1628,1783,2765,195,1850,803,1100,530,289,784,1852,615,312,2265,294,603,1534,1563,812,1446,977,1612,604,440,420,777,233,1161,1059,170,123,2769,118,59,508,1373,1223,370,470,539,215,258,284,279,22,330,320,825,91,414,313,628,66,174,2771,272,246,77,135,112,1885,1789,2420,1288,1311,227,1013,427,558,1575,1087,491,638,44,2375,307,2034,679,1352,1378,520,372,771,10,238,21,2894,1380,650,268,357,630,2273,478,81,580,1168,1133,1577,621,1356,45,23,31,467,767,152,179,1211,622,336,2197,998,1293,225,1230,240,683,733,2467,1489,321,322,441,986,599,1069,1016,1137,86,57,50,3,344,586,652,1235,720,1139,61,1643,1092,653,596,1407,1720,734,1623,577,318,28,196,298,254,136,1054,197,37,707 | 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| 2,948 |
Mitochondrial myopathy | 16 | 28 | 3.393238 | 0.000691 | O96000,Q9Y6M9,Q8IUX1,O43676,Q9BUK6,Q96CU9,Q86Y39,P00846,Q9NPL8,P12235,O75306,O60313,Q9NX14,Q53H12,P00403,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,37,135,8,584,44,77,14,240,433,339,219,441,539,60,95 | 8,219,839,339,1297,129,60,14,95,433,1825,2531,2765,1284,539,77,135,1789,44,584,2039,240,441,1137,2091,596,2400,37 | 3.0713505910312833,1.5813953757113124,0.28622861567613295,1.2295800256388367,-0.04562344444480704,1.9850015170325637,2.5059894136062666,3.0256480119669416,2.1700017598173678,0.9789156405018443,-0.3409143906622731,-0.7972875946120856,-1.1705743485850078,-0.032206450409452865,0.7579666967264426,2.343244888252367,1.9506190541438213,-0.31162085873717893,2.643303939387849,0.6841640874618475,-0.4455266972174347,1.4933010900118375,0.9692152220740943,0.07317166718379643,-0.4760292158199211,0.662747577217144,-0.6813481805247098,2.7015163290761643 | 2,948 |
Establishment of protein localization to mitochondrial membrane | 10 | 20 | 3.390828 | 0.000697 | Q9NS69,Q9Y5J7,P62072,Q9Y5J9,O60220,Q9Y5L4,Q9P0J0,O94826,Q15070,Q9Y584 | Processes and pathways | GO Biological process | msigdb_gobp | 2,196,294,298,302,254,86,89,59,28 | 1897,791,302,89,1527,1777,2362,2290,294,570,59,539,2,86,720,318,28,196,298,254 | -0.38534586462623527,0.34626792877763996,1.3172820683611308,2.2206406060146433,-0.1689335436139936,-0.31162085873717893,-0.6651033942270582,-0.6168313523355917,1.3345119408817352,0.7160115787906041,2.511621516710349,0.7579666967264426,3.2420278669660707,2.258009524162855,0.4630172524838215,1.2825150544453023,2.794047586014273,1.6515109252066653,1.3345119408817352,1.4523500544317842 | 2,948 |
Primary mitochondrial disease | 38 | 94 | 3.381667 | 0.00072 | O75208,Q96IX5,O43676,Q8IUX1,Q9BQT8,P00846,Q5XKP0,Q53H12,Q9Y584,P13073,O14949,O75880,Q9Y6M9,Q96CU9,Q7KZN9,P12235,Q8NI60,Q9NX14,Q9UBX3,P00403,Q9Y2R0,Q70HW3,O43819,Q6DKK2,Q86Y39,Q9Y375,O75306,Q9P0J0,Q9BUB7,Q6P4A7,O60313,P20674,P03886,O95831,P22695,Q9NPL8,Q9BRT2,Q9NWS8 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 381,520,8,135,268,14,279,539,28,155,33,288,37,44,174,433,558,441,57,60,61,66,582,330,77,596,339,86,478,91,219,601,95,359,109,240,630,248 | 1000,33,8,2677,582,219,721,381,839,339,1297,1238,288,2542,359,60,14,95,1985,809,2837,433,155,633,1825,601,109,1439,2531,1301,1849,2799,858,2263,2765,1284,1100,1393,1534,1612,1903,731,1223,539,1399,738,1569,2816,1224,279,330,91,66,174,1658,77,135,1789,2693,558,1541,971,44,520,1227,740,2376,2637,268,630,1694,478,760,1211,2197,240,248,441,1137,86,1836,57,720,1139,61,1092,2091,596,1407,734,1623,28,2400,37 | 0.15000139369493218,2.737894239182016,3.0713505910312833,-0.9877958305297942,0.6841640874618475,1.5813953757113124,0.451536002673528,1.1022436718162008,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.005537980331740621,1.3516408047634436,-0.8141766528354556,1.1756765413677428,2.5059894136062666,3.0256480119669416,2.1700017598173678,-0.43037928832775996,0.3223889389369212,-1.4032600540214297,0.9789156405018443,1.8663245911664819,0.5755625753080114,-0.3409143906622731,0.6411810535042607,2.059171659276056,-0.12730986022355953,-0.7972875946120856,-0.04562344444480704,-0.35565887677440616,-1.2850028396706408,0.27408278382771123,-0.6008926353532796,-1.1705743485850078,-0.032206450409452865,0.08610500976236193,-0.09985266152283995,-0.1689335436139936,-0.2110933158886262,-0.38534586462623527,0.44001246034412966,0.007714294292187978,0.7579666967264426,-0.09985266152283995,0.4284463495739996,-0.18292663566061074,-1.323985431825699,0.007714294292187978,1.3771469826873006,1.2561666700159204,2.1954390050858774,2.4719430888618175,1.772045557794017,-0.23950372309971943,2.343244888252367,1.9506190541438213,-0.31162085873717893,-1.0056477492818756,0.7370610056166005,-0.1689335436139936,0.18773580450914448,2.643303939387849,0.7993537399833668,0.007714294292187978,0.4284463495739996,-0.6651033942270582,-0.9172949987173196,1.4108112793572933,0.5865961083383107,-0.25380149284031334,0.8904664767159661,0.4051853060515837,0.020912454144430923,-0.5535235918543128,1.4933010900118375,1.4688001720482913,0.9692152220740943,0.07317166718379643,2.258009524162855,-0.3409143906622731,2.5617775528003315,0.4630172524838215,0.07317166718379643,2.500345305118897,0.09898651295405862,-0.4760292158199211,0.662747577217144,-0.09985266152283995,0.44001246034412966,-0.2110933158886262,2.794047586014273,-0.6813481805247098,2.7015163290761643 | 2,948 |
Hexosyltransferase activity | 13 | 29 | 3.378033 | 0.00073 | Q6ZXV5,Q8N4A0,P04843,Q9BT22,Q8TCJ2,O43505,Q10472,P46977,Q2TAA5,P35573,Q9NYU2,Q13126,P04062 | Functions | GO Molecular function | msigdb_gomf | 517,70,457,76,335,235,207,110,366,500,217,58,93 | 2332,235,545,1410,93,457,1074,2157,1038,2528,2206,1324,500,1119,110,1266,824,207,58,366,517,1149,70,1289,2029,335,76,1068,217 | -0.6489360930417204,1.509520209213793,0.7475317096601524,-0.11355235818258648,2.182750080789599,0.9300978254026866,0.09898651295405862,-0.5378809045039169,0.12459546086867959,-0.7972875946120856,-0.5692393713422798,-0.05909615052808124,0.8503091286584517,0.07317166718379643,2.059171659276056,-0.018844762829244025,0.3103813825441349,1.612770532132464,2.5340307722113398,1.1574880581635068,0.7993537399833668,0.060186115633053816,2.41421165375674,-0.032206450409452865,-0.4455266972174347,1.247331115968002,2.3611636015336126,0.11181654260448975,1.5892714807064798 | 2,948 |
Carbohydrate derivative transport | 13 | 15 | 3.373467 | 0.000742 | Q6NUK1,Q9HC21,P07602,O00400,L0R6Q1,P05141,Q8TB61,Q08722,O43808,Q96AA3,P12236,Q9NZJ7,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 320,225,324,362,299,303,79,117,405,186,154,189,94 | 299,362,405,303,324,433,154,688,117,320,79,94,186,225,189 | 1.325909696379107,1.1665962650895083,1.0364688150319994,1.3172820683611308,1.2649757514469988,0.9789156405018443,1.873447213431415,0.48585396547881715,2.0391403276957534,1.2737585000217826,2.325205828646418,2.176383375551823,1.7124191246748732,1.5655779034583233,1.6821282751850737 | 2,948 |
Lipid localization | 32 | 69 | 3.366945 | 0.00076 | P28288,Q9BQE5,Q7Z3C6,A0FGR8,Q99720,P17900,O43808,O15118,Q14108,O43772,Q96AA3,Q9NZJ7,Q9BZF1,P07602,Q14534,Q9H2V7,P08183,Q9BUR5,P30536,Q96GC9,Q86Y82,P04062,Q8WTV0,Q4KMQ2,P09455,P35610,P50416,Q9Y679,Q14849,P23786,O15260,Q9H6V9 | Processes and pathways | GO Biological process | msigdb_gobp | 515,4,518,513,21,145,405,151,54,567,186,189,581,324,75,467,332,81,597,221,605,93,94,352,480,224,97,492,104,232,369,120 | 513,2938,151,369,567,405,865,2284,1256,1003,1367,2508,93,1841,2132,324,2528,2763,332,480,1555,2850,145,1280,1157,1299,232,515,597,612,769,224,1651,97,688,1264,2314,2854,54,75,104,352,847,1309,518,605,2899,94,186,221,1425,21,4,1914,81,1813,581,2064,467,2565,1292,120,189,1318,1234,1235,2398,492,1434 | 0.7993537399833668,-4.846325496318681,1.8947068052131284,1.1483517684971725,0.7160115787906041,1.0364688150319994,0.26189023374501835,-0.6168313523355917,-0.018844762829244025,0.15000139369493218,-0.08621034266007742,-0.780481520558001,2.182750080789599,-0.35565887677440616,-0.5223107110430917,1.2649757514469988,-0.7972875946120856,-1.1705743485850078,1.247331115968002,0.8804769315934403,-0.18292663566061074,-1.4435695136020075,1.9017575126557482,-0.032206450409452865,0.047147981735179874,-0.04562344444480704,1.5175956622312197,0.7993537399833668,0.6519831828829221,0.6194626505037427,0.3817506123919569,1.5655779034583233,-0.23950372309971943,2.137867848356007,0.48585396547881715,-0.018844762829244025,-0.6328456266009942,-1.4435695136020075,2.572795002492806,2.3611636015336126,2.105351748565537,1.1937539044717103,0.28622861567613295,-0.04562344444480704,0.7993537399833668,0.6411810535042607,-1.850858038664009,2.176383375551823,1.7124191246748732,1.5813953757113124,-0.11355235818258648,2.936470354523948,3.190745333119537,-0.38534586462623527,2.3009640601712826,-0.3262352210800657,0.6948166616430476,-0.46074315377249025,0.9202386350075965,-0.8311494216532105,-0.032206450409452865,2.032430731714956,1.6821282751850737,-0.04562344444480704,0.007714294292187978,0.007714294292187978,-0.6813481805247098,0.8704543213377697,-0.11355235818258648 | 2,948 |
Establishment of protein localization to membrane | 35 | 86 | 3.360083 | 0.000779 | Q9NS69,P43307,Q15629,P40855,P61026,Q96A33,O15118,O60725,Q53H12,Q9Y584,Q4J6C6,P61619,P62072,Q9Y5J9,O60220,O43681,Q9Y512,Q15070,P27105,Q9UGP8,Q9Y5J7,P49069,Q15904,P46379,Q9HD20,Q9P0J0,O94826,Q99442,P05026,Q8N4V1,Q8NBU5,Q9NPA0,Q9Y5L4,Q9H4A6,Q5J8M3 | Processes and pathways | GO Biological process | msigdb_gobp | 2,1,130,395,269,143,151,24,539,28,162,419,294,298,302,555,318,59,311,453,196,201,329,458,83,86,89,347,479,102,489,244,254,384,510 | 864,1897,791,854,151,555,2657,302,24,1700,2697,89,1003,479,1527,1219,1777,1528,311,2362,2533,612,2290,2212,395,1988,1,458,2585,201,1178,833,1562,1344,2751,1734,269,419,294,2881,921,2121,1536,570,1905,1396,1967,749,1102,1062,59,130,329,162,539,510,2104,102,1209,489,1637,143,2423,347,704,772,384,2892,83,705,244,2,1715,86,453,1769,2540,2486,974,720,838,318,28,196,298,254 | 0.26189023374501835,-0.38534586462623527,0.34626792877763996,0.27408278382771123,1.8947068052131284,0.7370610056166005,-0.9523656803307052,1.3172820683611308,2.839099659223572,-0.26816160686466817,-1.0235920080980971,2.2206406060146433,0.15000139369493218,0.8804769315934403,-0.1689335436139936,0.007714294292187978,-0.31162085873717893,-0.1689335436139936,1.2825150544453023,-0.6651033942270582,-0.7972875946120856,0.6194626505037427,-0.6168313523355917,-0.5692393713422798,1.0648357439505178,-0.43037928832775996,3.2420278669660707,0.9300978254026866,-0.8653490426838603,1.643804841337337,0.034056888274781295,0.2983280445189644,-0.18292663566061074,-0.07262497853037561,-1.133244923304272,-0.2825845468972897,1.4024316796859169,1.007830322351225,1.3345119408817352,-1.6095037071757186,0.22502907537646621,-0.5068124202196339,-0.1689335436139936,0.7160115787906041,-0.38534586462623527,-0.09985266152283995,-0.4153003756640121,0.41683739185316737,0.08610500976236193,0.11181654260448975,2.511621516710349,1.9850015170325637,1.2561666700159204,1.8448473069506741,0.7579666967264426,0.8096133248148545,-0.4913854476709634,2.111885928965945,0.020912454144430923,0.8704543213377697,-0.22526782119676403,1.9297833441110366,-0.6976711102245209,1.2117213408631573,0.474456483139522,0.3817506123919569,1.1022436718162008,-1.71722930421042,2.2641878529287944,0.474456483139522,1.4769902629485032,3.2420278669660707,-0.26816160686466817,2.258009524162855,0.9399248957090145,-0.29707080001748704,-0.7972875946120856,-0.7471154641344182,0.18773580450914448,0.4630172524838215,0.2983280445189644,1.2825150544453023,2.794047586014273,1.6515109252066653,1.3345119408817352,1.4523500544317842 | 2,948 |
Endoplasmic reticulum | 84 | 195 | 3.34598 | 0.00082 | O43169,P43307,O43731,Q16799,Q9BUN8,Q86UE4,Q8N0U8,O95197,Q15800,Q9P2W9,Q9NQC3,Q96G23,O95470,O00264,Q96A57,P51648,Q9BT22,Q5BJF2,Q14849,Q8NF37,Q96KA5,Q9H3N1,Q96KC8,Q14257,O60831,O75845,Q96A33,Q9Y680,P84157,P21964,O96005,Q86Y07,Q86XL3,Q16850,Q8TCT9,P50402,Q8NHH9,Q96AG4,Q9P035,Q96GC9,P35610,P27544,Q6NUQ4,Q9H3G5,Q86TM6,Q96S66,Q00765,Q8IV08,P48651,Q12981,Q03519,O43852,Q99735,O43292,O75915,Q8TCJ2,O00767,Q6UWP7,Q9UBM7,Q99442,O14681,Q9HCU5,P49257,Q9H6H4,Q8NHP6,O15260,Q15043,P51571,P27824,P51572,Q9NZ01,Q9UM00,Q6UW68,Q9GZP9,P61619,Q96CS3,Q92791,Q70UQ0,Q9UGP8,P04843,Q6PIU2,P0CG08,P37268,Q8WUJ1 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 0,1,5,12,17,26,27,30,34,40,46,47,64,67,68,71,76,101,104,107,113,115,127,125,133,137,143,153,157,161,173,178,181,185,187,195,202,209,214,221,224,229,237,243,242,253,252,255,257,273,281,300,308,310,327,335,338,342,343,347,350,355,361,365,368,369,382,392,390,396,410,411,415,418,419,428,432,445,453,457,460,463,468,477 | 1624,67,338,350,1821,854,369,474,773,0,2489,310,5,300,1436,133,881,137,327,882,942,30,623,64,173,944,457,1074,2864,735,568,2732,2229,463,2745,1842,669,1098,1465,1798,641,1930,2075,1117,2644,161,2740,1501,1586,229,961,1847,390,1754,1412,2645,1781,224,1203,468,1626,2584,1,1261,2560,1325,1262,1504,1220,257,1042,361,195,1283,2214,392,396,71,1344,2473,2137,993,1241,419,1180,2018,1394,1937,1736,730,2099,2573,1471,1938,764,2822,1684,2266,1759,2515,1122,2648,2599,920,1181,978,157,252,281,1564,887,273,1474,1060,1304,737,125,1186,1513,104,1102,382,1348,571,2616,1064,34,12,185,2855,101,237,460,1944,415,342,445,242,26,1029,181,178,255,27,665,2029,1420,107,202,368,335,187,904,477,432,143,68,209,816,428,703,47,221,532,113,127,253,347,308,2907,1107,1914,76,17,910,418,243,115,365,355,46,542,2874,410,214,2042,40,343,453,852,411,1236,2011,153,1434 | 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| 2,948 |
Abnormality of head blood vessel | 10 | 25 | 3.321917 | 0.000894 | P10619,P48651,P21964,P16278,P00846,Q13510,P17900,Q9Y4P3,Q9NZJ7,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,257,161,199,14,84,145,249,189,95 | 1722,2226,2403,14,95,1038,324,2528,96,2306,199,145,989,161,1299,842,257,2363,1965,84,845,1912,189,1458,249 | -0.2825845468972897,-0.5850288483198346,-0.6976711102245209,3.0256480119669416,2.1700017598173678,0.12459546086867959,1.2649757514469988,-0.7972875946120856,2.163605171803125,-0.6328456266009942,1.643804841337337,1.9017575126557482,0.16262911454544973,1.8448473069506741,-0.04562344444480704,0.28622861567613295,1.4358059044741707,-0.6651033942270582,-0.4153003756640121,2.258009524162855,0.28622861567613295,-0.38534586462623527,1.6821282751850737,-0.12730986022355953,1.4688001720482913 | 2,948 |
Organic acid transport | 27 | 42 | 3.315599 | 0.000914 | P28288,O60831,Q9UJS0,Q9Y619,Q9BQT8,O43808,P53007,Q9H2D1,Q02978,O43772,Q96QD8,P08195,Q9UBX3,O75746,O75915,Q9H9B4,P08183,P53985,Q6P4A7,P09455,P50416,P31751,P23786,P30825,Q9H936,Q96NB2,Q9H2H9 | Processes and pathways | GO Biological process | msigdb_gobp | 515,133,652,136,268,405,530,31,420,567,183,569,57,456,327,336,332,465,91,480,97,612,232,236,622,372,631 | 2908,567,405,133,456,327,1003,2508,1841,735,2763,332,569,480,2850,989,232,515,236,612,769,97,530,465,1159,420,1102,1062,663,1309,91,1376,372,183,268,31,631,622,336,57,652,136 | -1.9660618459113863,0.7160115787906041,1.0364688150319994,1.957529717511198,0.9300978254026866,1.2561666700159204,0.15000139369493218,-0.780481520558001,-0.35565887677440616,0.4284463495739996,-1.1705743485850078,1.247331115968002,0.7160115787906041,0.8804769315934403,-1.4435695136020075,0.16262911454544973,1.5175956622312197,0.7993537399833668,1.509520209213793,0.6194626505037427,0.3817506123919569,2.137867848356007,0.7683661814306533,0.9202386350075965,0.047147981735179874,1.007830322351225,0.08610500976236193,0.11181654260448975,0.5197985937189371,-0.04562344444480704,2.1954390050858774,-0.08621034266007742,1.1483517684971725,1.719941539725816,1.4108112793572933,2.7635696710490953,0.5865961083383107,0.6085459020758718,1.247331115968002,2.5617775528003315,0.553377001040428,1.9506190541438213 | 2,948 |
Protein localization to endoplasmic reticulum | 17 | 33 | 3.287679 | 0.00101 | O43292,Q15629,O15258,P61619,O43731,Q9UGP8,P46379,P24390,P51572,P61026,P33908,Q9NQC3,Q5JRA6,Q99442,Q96HY6,Q15005,Q9Y5M8 | Processes and pathways | GO Biological process | msigdb_gobp | 310,130,286,419,5,453,458,11,396,269,556,46,400,347,532,283,62 | 854,286,310,555,5,2657,2697,1219,857,11,556,2212,458,1178,396,1344,2757,1827,1734,269,419,283,1062,130,400,1151,532,347,704,46,453,1769,62 | 0.27408278382771123,1.3516408047634436,1.2825150544453023,0.7370610056166005,3.16470177536829,-0.9523656803307052,-1.0235920080980971,0.007714294292187978,0.27408278382771123,3.044028574777508,0.7370610056166005,-0.5692393713422798,0.9300978254026866,0.034056888274781295,1.0648357439505178,-0.07262497853037561,-1.151859916150363,-0.3409143906622731,-0.2825845468972897,1.4024316796859169,1.007830322351225,1.3601676844230879,0.11181654260448975,1.9850015170325637,1.0554099937856247,0.060186115633053816,0.7683661814306533,1.2117213408631573,0.474456483139522,2.6379469928697454,0.9399248957090145,-0.29707080001748704,2.500345305118897 | 2,948 |
Carboxylic acid transport | 21 | 32 | 3.271495 | 0.00107 | P28288,O60831,Q9UJS0,Q9Y619,Q9BQT8,P53007,Q9H2D1,Q02978,Q96QD8,P08195,Q9UBX3,Q9NZJ7,P07602,O75746,O75915,Q9H9B4,P53985,P30825,Q9H936,Q96NB2,Q9H2H9 | Processes and pathways | GO Biological process | msigdb_gobp | 515,133,652,136,268,530,31,420,183,569,57,189,324,456,327,336,465,236,622,372,631 | 2908,133,456,327,1841,735,324,569,2850,989,515,236,530,465,1159,420,1102,1062,663,1309,1376,372,183,268,31,631,622,336,189,57,652,136 | -1.9660618459113863,1.957529717511198,0.9300978254026866,1.2561666700159204,-0.35565887677440616,0.4284463495739996,1.2649757514469988,0.7160115787906041,-1.4435695136020075,0.16262911454544973,0.7993537399833668,1.509520209213793,0.7683661814306533,0.9202386350075965,0.047147981735179874,1.007830322351225,0.08610500976236193,0.11181654260448975,0.5197985937189371,-0.04562344444480704,-0.08621034266007742,1.1483517684971725,1.719941539725816,1.4108112793572933,2.7635696710490953,0.5865961083383107,0.6085459020758718,1.247331115968002,1.6821282751850737,2.5617775528003315,0.553377001040428,1.9506190541438213 | 2,948 |
Ire1alpha activates chaperones | 8 | 25 | 3.268246 | 0.001082 | P43307,Q9HCU5,O43731,Q9NWM8,O14773,Q86TM6,O95070,Q9Y5M8 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1,355,5,261,234,242,116,62 | 234,5,424,1870,116,868,1219,1005,1,1783,1559,2337,1371,1760,1060,1476,1348,242,701,1351,355,261,2330,1319,62 | 1.509520209213793,3.16470177536829,0.998223014412092,-0.37046919446512544,2.0391403276957534,0.26189023374501835,0.007714294292187978,0.15000139369493218,3.2420278669660707,-0.31162085873717893,-0.18292663566061074,-0.6489360930417204,-0.08621034266007742,-0.29707080001748704,0.11181654260448975,-0.14112559981342382,-0.07262497853037561,1.4769902629485032,0.474456483139522,-0.07262497853037561,1.1937539044717103,1.4358059044741707,-0.6328456266009942,-0.04562344444480704,2.500345305118897 | 2,948 |
Outer mitochondrial membrane protein complex | 11 | 16 | 3.254004 | 0.001138 | Q9NVH1,Q9NS69,Q9BUR5,Q8N4H5,Q5XKP0,Q6UXV4,Q5HYI7,Q9Y512,O94826,Q13505,O75431 | Localization | GO Cellular component | msigdb_gocc | 321,2,81,19,279,313,215,318,89,123,223 | 223,89,685,2543,123,1084,370,215,279,313,19,81,2,321,599,318 | 1.5655779034583233,2.2206406060146433,0.48585396547881715,-0.8141766528354556,2.0189623913532273,0.09898651295405862,1.1483517684971725,1.5892714807064798,1.3771469826873006,1.2825150544453023,2.9507609398023713,2.3009640601712826,3.2420278669660707,1.2737585000217826,0.6519831828829221,1.2825150544453023 | 2,948 |
Abnormal brainstem mri signal intensity | 10 | 21 | 3.247433 | 0.001165 | O96000,Q9Y6M9,Q8IUX1,O43676,O95831,Q96CU9,Q86Y39,Q9NPL8,O75306,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,37,135,8,359,44,77,240,339,95 | 8,839,339,1297,359,129,95,1825,2531,1467,2765,77,135,1789,971,44,240,441,1137,596,37 | 3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,1.1756765413677428,1.9850015170325637,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-0.14112559981342382,-1.1705743485850078,2.343244888252367,1.9506190541438213,-0.31162085873717893,0.18773580450914448,2.643303939387849,1.4933010900118375,0.9692152220740943,0.07317166718379643,0.662747577217144,2.7015163290761643 | 2,948 |
Inorganic anion transport | 14 | 24 | 3.234589 | 0.001218 | Q15043,Q4KMQ2,P51790,Q02978,Q9NW15,Q9UHG3,P45880,P21796,Q9C0H2,P08183,Q00325,Q9UBX3,Q96S66,Q9Y277 | Processes and pathways | GO Biological process | msigdb_gobp | 382,352,387,420,168,42,13,15,16,332,440,57,253,159 | 2355,555,332,463,15,1299,597,13,387,1707,965,1159,440,420,382,352,2888,253,16,168,57,42,159,2776 | -0.6651033942270582,0.7370610056166005,1.247331115968002,0.9202386350075965,3.021031890458238,-0.04562344444480704,0.6519831828829221,3.03485502403842,1.0929356242486823,-0.26816160686466817,0.18773580450914448,0.047147981735179874,0.9692152220740943,1.007830322351225,1.1022436718162008,1.1937539044717103,-1.673754024156004,1.4523500544317842,3.021031890458238,1.8304371083321016,2.5617775528003315,2.648649937374481,1.8520247203194133,-1.1705743485850078 | 2,948 |
Decreased activity of mitochondrial complex i | 10 | 34 | 3.230672 | 0.001235 | O96000,Q70HW3,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q86Y39,Q9UBX3,Q9Y584,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,66,37,135,8,44,77,57,28,95 | 8,2677,839,339,1297,129,95,1825,2531,2799,2765,803,1100,1393,1399,2816,66,77,135,1789,971,44,1352,1227,2039,1211,240,441,1137,57,596,1623,28,37 | 3.0713505910312833,-0.9877958305297942,0.28622861567613295,1.2295800256388367,-0.04562344444480704,1.9850015170325637,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-1.2850028396706408,-1.1705743485850078,0.33435101991744987,0.08610500976236193,-0.09985266152283995,-0.09985266152283995,-1.323985431825699,2.4719430888618175,2.343244888252367,1.9506190541438213,-0.31162085873717893,0.18773580450914448,2.643303939387849,-0.07262497853037561,0.007714294292187978,-0.4455266972174347,0.020912454144430923,1.4933010900118375,0.9692152220740943,0.07317166718379643,2.5617775528003315,0.662747577217144,-0.2110933158886262,2.794047586014273,2.7015163290761643 | 2,948 |
Lipoprotein metabolic process | 10 | 20 | 3.224835 | 0.00126 | Q9NUJ1,Q9BQE5,P50897,Q8IUH4,Q5H8A4,Q8N2K0,Q8NEB9,P04062,O43292,Q92643 | Processes and pathways | GO Biological process | msigdb_gobp | 194,4,78,176,149,250,346,93,310,291 | 310,545,1700,1648,93,2362,78,1062,149,1591,176,250,346,291,588,4,704,375,194,2506 | 1.2825150544453023,0.7475317096601524,-0.26816160686466817,-0.23950372309971943,2.182750080789599,-0.6651033942270582,2.325205828646418,0.11181654260448975,1.9017575126557482,-0.19697974106199748,1.757256508499432,1.4605868082268154,1.2117213408631573,1.3516408047634436,0.6734744686950634,3.190745333119537,0.474456483139522,1.1299943266097154,1.666860800458015,-0.7637577132524961 | 2,948 |
Increased csf lactate | 16 | 50 | 3.223762 | 0.001265 | O96000,Q9HC21,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q7KZN9,P00846,Q86Y39,Q9NPL8,O75306,Q9P0J0,Q9NWS8,P13073,P00403,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,225,37,135,8,44,174,14,77,240,339,86,248,155,60,95 | 782,1000,694,8,582,839,339,1297,2542,359,129,60,14,95,1985,155,1825,2531,2661,1301,1875,2700,1849,2765,1756,803,1393,1612,1223,620,174,1658,77,135,1789,2899,558,1541,44,1227,2501,1694,225,240,248,441,1137,86,596,37 | 0.3581399659175588,0.15000139369493218,0.474456483139522,3.0713505910312833,0.6841640874618475,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.8141766528354556,1.1756765413677428,1.9850015170325637,2.5059894136062666,3.0256480119669416,2.1700017598173678,-0.43037928832775996,1.8663245911664819,-0.3409143906622731,-0.7972875946120856,-0.9523656803307052,-0.04562344444480704,-0.37046919446512544,-1.0235920080980971,-0.35565887677440616,-1.1705743485850078,-0.29707080001748704,0.33435101991744987,-0.09985266152283995,-0.2110933158886262,0.007714294292187978,0.6085459020758718,1.772045557794017,-0.23950372309971943,2.343244888252367,1.9506190541438213,-0.31162085873717893,-1.850858038664009,0.7370610056166005,-0.1689335436139936,2.643303939387849,0.007714294292187978,-0.7637577132524961,-0.25380149284031334,1.5655779034583233,1.4933010900118375,1.4688001720482913,0.9692152220740943,0.07317166718379643,2.258009524162855,0.662747577217144,2.7015163290761643 | 2,948 |
Dementia | 31 | 57 | 3.22141 | 0.001276 | Q96RL7,P00846,P09651,P17900,Q8N5K1,O15118,Q9Y487,P43243,P61916,O76024,Q8WVX9,Q9NQZ5,P20700,O60220,O96008,O43681,Q14108,P00403,P21912,Q9NZJ7,P07602,Q9UBB4,Q13510,O60313,P04062,P04350,P03886,P22626,P27544,P35670,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 383,14,657,145,665,151,292,674,688,424,561,172,687,302,685,555,54,60,188,189,324,590,84,219,93,351,95,611,229,494,379 | 807,151,694,555,302,219,1524,424,685,60,14,95,93,2228,351,1038,324,657,1872,145,687,188,611,2383,229,1301,1041,379,494,1442,2312,674,1756,784,2052,688,2315,1010,2496,84,54,1476,738,1805,665,561,1948,2423,383,2885,172,2928,189,590,1362,1018,292 | 0.3223889389369212,1.8947068052131284,0.474456483139522,0.7370610056166005,1.3172820683611308,1.5813953757113124,-0.1689335436139936,0.998223014412092,0.48585396547881715,2.5059894136062666,3.0256480119669416,2.1700017598173678,2.182750080789599,-0.5850288483198346,1.1937539044717103,0.12459546086867959,1.2649757514469988,0.5310317416999976,-0.37046919446512544,1.9017575126557482,0.48585396547881715,1.6897313558966025,0.6194626505037427,-0.6813481805247098,1.5416869382636196,-0.04562344444480704,0.12459546086867959,1.1115226986611575,0.8603984521649488,-0.12730986022355953,-0.6328456266009942,0.4972099678438886,-0.29707080001748704,0.3581399659175588,-0.46074315377249025,0.48585396547881715,-0.6328456266009942,0.15000139369493218,-0.7637577132524961,2.258009524162855,2.572795002492806,-0.14112559981342382,0.4284463495739996,-0.3262352210800657,0.5197985937189371,0.7370610056166005,-0.40028941407932933,-0.6976711102245209,1.1022436718162008,-1.6307939198566663,1.8013928596418074,-2.8601405847797996,1.6821282751850737,0.6734744686950634,-0.07262497853037561,0.15000139369493218,1.3516408047634436 | 2,948 |
Protein transporter activity | 12 | 15 | 3.212149 | 0.001317 | Q9NS69,Q9UGP8,P61619,Q8NBU5,Q99595,Q9Y5J9,O14925,O60830,Q9HD20,O94826,P49755,Q9Y584 | Functions | GO Molecular function | msigdb_gomf | 2,453,419,489,10,298,108,49,83,89,220,28 | 108,49,89,685,220,419,516,1084,489,10,83,2,453,28,298 | 2.059171659276056,2.605573158951584,2.2206406060146433,0.48585396547881715,1.5813953757113124,1.007830322351225,0.7993537399833668,0.09898651295405862,0.8704543213377697,3.0668174590396893,2.2641878529287944,3.2420278669660707,0.9399248957090145,2.794047586014273,1.3345119408817352 | 2,948 |
Abnormal mitochondria in muscle tissue | 10 | 21 | 3.211265 | 0.001322 | O96000,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q86Y39,Q9NPL8,O75306,P00403,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,37,135,8,44,77,240,339,60,95 | 8,839,339,1297,129,60,95,1825,2531,1301,2765,77,135,1789,44,240,441,1137,596,577,37 | 3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,1.9850015170325637,2.5059894136062666,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-0.04562344444480704,-1.1705743485850078,2.343244888252367,1.9506190541438213,-0.31162085873717893,2.643303939387849,1.4933010900118375,0.9692152220740943,0.07317166718379643,0.662747577217144,0.705432417367614,2.7015163290761643 | 2,948 |
Abnormal retinal artery morphology | 9 | 22 | 3.202751 | 0.001361 | P10619,P21964,P16278,P00846,Q13510,P17900,Q9Y4P3,Q9NZJ7,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,161,199,14,84,145,249,189,95 | 2226,2403,14,95,1038,324,2528,96,2306,199,145,161,1299,842,2363,1965,84,845,1912,189,1458,249 | -0.5850288483198346,-0.6976711102245209,3.0256480119669416,2.1700017598173678,0.12459546086867959,1.2649757514469988,-0.7972875946120856,2.163605171803125,-0.6328456266009942,1.643804841337337,1.9017575126557482,1.8448473069506741,-0.04562344444480704,0.28622861567613295,-0.6651033942270582,-0.4153003756640121,2.258009524162855,0.28622861567613295,-0.38534586462623527,1.6821282751850737,-0.12730986022355953,1.4688001720482913 | 2,948 |
Proton transmembrane transporter activity | 22 | 40 | 3.198973 | 0.001379 | P51790,O95202,Q93050,P00846,P13073,Q9Y487,Q13423,Q7KZN9,P05141,P12235,Q9UDW1,Q96ES6,Q00325,P56385,P00403,P06576,O14548,O75964,P20674,P56134,P24539,O00400 | Functions | GO Molecular function | msigdb_gomf | 387,138,142,14,155,292,170,174,303,433,50,309,440,312,60,572,448,88,601,615,231,362 | 362,448,1774,88,138,60,14,303,572,809,686,433,155,810,601,1609,2792,231,1439,1441,900,1442,2312,858,2459,387,615,312,1371,440,170,174,142,309,2894,622,50,2450,292,1770 | 1.1665962650895083,0.9399248957090145,-0.31162085873717893,2.233154239652949,1.9436911549131641,2.5059894136062666,3.0256480119669416,1.3172820683611308,0.705432417367614,0.3223889389369212,0.48585396547881715,0.9789156405018443,1.8663245911664819,0.3223889389369212,0.6411810535042607,-0.2110933158886262,-1.2656715296047802,1.525648527311823,-0.12730986022355953,-0.12730986022355953,0.23736370252558897,-0.12730986022355953,-0.6328456266009942,0.27408278382771123,-0.7305540733601957,1.0929356242486823,0.6085459020758718,1.2825150544453023,-0.08621034266007742,0.9692152220740943,1.808682116385517,1.772045557794017,1.9297833441110366,1.2999501304431609,-1.7612307722767848,0.6085459020758718,2.6001384504964156,-0.7140728496646459,1.3516408047634436,-0.29707080001748704 | 2,948 |
Transporter complex | 23 | 55 | 3.181102 | 0.001467 | O96000,O43676,O75381,Q9C0H2,O14949,Q9Y6M9,P62072,Q8NE86,Q9Y5J9,Q96CU9,P05023,O60220,Q9UDW1,Q9Y5J7,Q86Y39,O75306,Q9P0J0,P03886,Q4KMQ2,P22695,Q8N2K0,Q96S66,Q9Y5L4 | Localization | GO Cellular component | msigdb_gocc | 129,8,398,16,33,37,294,427,298,44,301,302,50,196,77,339,86,95,352,109,250,253,254 | 2355,1000,33,8,302,839,339,398,1297,2095,2335,2542,129,95,301,479,809,1777,633,1825,109,2531,1441,858,2765,1707,803,1560,918,294,1330,1103,1373,1223,352,77,1885,250,427,44,679,253,1380,2947,16,441,86,50,720,596,196,298,254,2776,37 | -0.6651033942270582,0.15000139369493218,2.737894239182016,3.0713505910312833,1.3172820683611308,0.28622861567613295,1.2295800256388367,1.0554099937856247,-0.04562344444480704,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.1700017598173678,1.325909696379107,0.8804769315934403,0.3223889389369212,-0.31162085873717893,0.5755625753080114,-0.3409143906622731,2.059171659276056,-0.7972875946120856,-0.12730986022355953,0.27408278382771123,-1.1705743485850078,-0.26816160686466817,0.33435101991744987,-0.18292663566061074,0.22502907537646621,1.3345119408817352,-0.05909615052808124,0.08610500976236193,-0.08621034266007742,0.007714294292187978,1.1937539044717103,2.343244888252367,-0.37046919446512544,1.4605868082268154,0.998223014412092,2.643303939387849,0.4972099678438886,1.4523500544317842,-0.08621034266007742,-7.699729873133215,3.021031890458238,0.9692152220740943,2.258009524162855,2.6001384504964156,0.4630172524838215,0.662747577217144,1.6515109252066653,1.3345119408817352,1.4523500544317842,-1.1705743485850078,2.7015163290761643 | 2,948 |
Organelle subcompartment | 187 | 354 | 3.179803 | 0.001474 | O75396,P43307,Q9BQE5,O43731,Q7Z3C6,A0FGR8,P30519,P24390,Q16799,Q9BUN8,Q99720,Q96HY6,O60725,Q8NBN3,Q86UE4,Q8N0U8,P09601,O95197,Q15800,Q9HC07,Q9BS26,O14828,Q9P2W9,O60762,O75844,Q9NQC3,Q96G23,A1L0T0,Q8TEM1,Q12907,Q9Y282,O60499,Q14108,O15533,O75298,Q07812,Q9Y5M8,Q8N511,O95470,Q8WWQ0,O00264,Q96A57,P51648,O00461,Q14534,Q9BT22,Q8TB61,Q9BUR5,Q9HD20,P04062,Q8N5M9,P04035,Q5BJF2,Q8N4V1,Q14849,Q8NF37,P46977,Q9NUQ2,Q9H3N1,O95070,Q14739,P16615,Q96KC8,Q07065,P57088,Q15629,Q15392,O75845,Q96A33,Q5H8A4,Q5VYK3,Q9UKU0,Q4J6C6,O43752,Q15363,Q86Y07,Q86XL3,Q96JJ7,Q96AA3,Q16850,Q8TCT9,Q9Y3B3,Q92604,P50402,P16435,P49069,Q8NHH9,Q96N66,Q10472,Q96AG4,P07099,Q9P035,Q8NFQ8,Q96GC9,P49755,Q9BU23,P35610,Q96RQ1,P27544,Q10713,Q6NUQ4,Q9NPA0,Q86TM6,Q9BSR8,Q9Y4P3,Q8N2K0,Q96S66,Q00765,Q8IV08,P48651,Q6NUM9,P61026,O15127,Q12981,Q03519,O14880,Q15005,Q92643,Q969E2,O43852,Q99735,Q99640,Q9Y320,Q9NZ08,O43292,Q9NPR9,A2RRP1,Q15904,Q8TBA6,O75915,P67812,Q8TCJ2,O00767,Q6UWP7,Q9UBM7,Q99442,O14681,Q9BVC6,Q9HCU5,Q9NTJ5,P49257,O00400,Q5VV42,Q9H6H4,Q2TAA5,Q8N2F6,Q8NHP6,O15260,Q9H490,Q53GQ0,O95864,Q9H4A6,Q96RL7,P51571,Q6IAN0,P27824,P51572,Q5JRA6,Q99523,Q9NZ01,Q9UM00,Q8N9F7,Q9GZP9,P61019,P61619,Q9Y394,Q96CS3,O76024,Q9Y3A6,P35613,O75787,Q70UQ0,Q9UGP8,P04843,Q6PIU2,P0CG08,P37268,Q04656,P04439,O15269,Q9Y679,Q14789,P35670,Q13190,O60858,Q9HA82,Q5J8M3 | Localization | GO Cellular component | msigdb_gocc | 514,1,4,5,518,513,9,11,12,17,21,532,24,25,26,27,29,30,34,35,550,544,40,545,43,46,47,554,559,557,52,53,54,566,56,570,62,63,64,578,67,68,71,74,75,76,79,81,83,93,98,100,101,102,104,107,110,111,115,116,118,122,127,124,128,130,134,137,143,149,150,158,162,171,177,178,181,182,186,185,187,190,193,195,200,201,202,204,207,209,211,214,216,221,220,222,224,228,229,233,237,244,242,247,249,250,253,252,255,257,259,269,270,273,281,282,283,291,296,300,308,315,317,316,310,326,323,329,331,327,334,335,338,342,343,347,350,353,355,356,361,362,364,365,366,367,368,369,375,376,378,384,383,392,393,390,396,400,401,410,411,416,418,413,419,429,428,424,437,439,443,445,453,457,460,463,468,469,475,474,492,487,494,495,497,512,510 | 513,554,323,67,362,807,74,338,2012,350,544,282,1821,854,1494,270,369,474,693,566,2489,310,694,5,2129,171,1037,300,2155,1773,53,24,545,1646,497,2356,56,1410,881,514,1955,443,43,137,327,424,882,2014,942,840,1870,116,30,623,1648,64,1256,2749,1003,378,1367,944,614,100,93,475,457,1074,1156,211,1219,1202,1257,29,463,658,1076,1465,200,122,641,1177,2851,1280,2699,11,1440,229,1847,390,2626,2689,1412,9,2077,2181,769,1781,224,439,494,468,1626,1369,1204,1,2585,110,1240,946,257,1651,201,361,1178,220,195,1390,935,1706,392,396,71,659,793,2820,2866,2787,2439,2363,2052,128,2646,1344,2757,2494,2751,1827,413,269,804,1008,2872,419,1180,872,1879,1330,1655,2267,334,1025,921,2587,252,1183,1266,813,281,469,124,570,2901,748,824,207,2140,233,887,557,273,495,1762,2725,737,54,1186,75,118,487,104,2024,283,749,1102,1062,1348,1103,177,134,1515,130,1064,34,329,12,185,366,162,376,101,149,510,400,1830,364,150,393,259,672,237,2844,1309,460,342,445,981,518,242,26,1029,181,178,255,2104,1334,27,367,250,102,63,665,98,1209,416,25,107,216,202,368,2372,79,331,787,335,1541,187,559,1863,578,1350,1151,193,291,1912,296,588,702,906,143,68,186,209,428,1376,47,221,1423,532,182,127,204,383,228,253,347,401,315,21,308,2907,2502,4,550,1914,247,76,607,222,17,81,353,829,1314,1428,581,910,418,1917,704,115,375,772,384,2565,365,2892,2425,512,35,355,83,851,244,326,46,2675,2549,356,111,1834,643,410,316,214,2042,40,2199,2200,343,453,1234,2486,158,852,706,411,2550,1215,52,1521,317,429,2656,437,190,2453,249,62,2011,1771,1387,492,1434 | 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| 2,948 |
Metal ion homeostasis | 32 | 77 | 3.176235 | 0.001492 | Q15043,Q6P4Q7,P30519,O14617,O95202,P51572,Q96A33,Q9UM00,P09601,Q9Y487,O75880,Q9HC07,Q8NE86,P05023,O76024,Q8NE01,Q07812,Q9Y4W6,Q8N511,P19174,Q15904,Q9HD20,Q8TAD4,Q04656,P05026,Q96AQ8,P20020,P23634,P35670,Q16891,O75027,P16615 | Processes and pathways | GO Biological process | msigdb_gobp | 382,263,9,389,138,396,143,411,29,292,288,35,427,301,424,435,570,577,63,328,329,83,87,469,479,491,485,493,494,370,374,122 | 1897,389,582,2666,1436,374,288,2895,424,138,623,1343,2430,301,479,2528,2357,1116,29,1777,2097,1465,122,328,485,2721,493,2880,1847,2734,9,2077,494,2312,396,1629,918,1159,1371,1146,1330,675,921,2121,469,570,1905,2562,2725,382,1103,329,370,263,1334,1885,63,435,427,87,143,491,1423,850,732,1380,2039,1599,35,83,1834,1235,411,292,577,743,707 | -0.38534586462623527,1.0835983952732648,0.6841640874618475,-0.9700354159181358,-0.12730986022355953,1.1299943266097154,1.3516408047634436,-1.8282445079663983,0.998223014412092,1.9436911549131641,0.5975904689424487,-0.07262497853037561,-0.7140728496646459,1.325909696379107,0.8804769315934403,-0.7972875946120856,-0.6651033942270582,0.07317166718379643,2.773768964357425,-0.31162085873717893,-0.4913854476709634,-0.14112559981342382,2.0189623913532273,1.2561666700159204,0.8704543213377697,-1.0597609447700629,0.8603984521649488,-1.6095037071757186,-0.35565887677440616,-1.077987350196644,3.0668174590396893,-0.4760292158199211,0.8603984521649488,-0.6328456266009942,1.0648357439505178,-0.22526782119676403,0.22502907537646621,0.047147981735179874,-0.08621034266007742,0.060186115633053816,-0.05909615052808124,0.4972099678438886,0.22502907537646621,-0.5068124202196339,0.9103471386411612,0.7160115787906041,-0.38534586462623527,-0.8311494216532105,-1.0597609447700629,1.1022436718162008,0.08610500976236193,1.2561666700159204,1.1483517684971725,1.4274982699452592,-0.05909615052808124,-0.37046919446512544,2.4946891459781244,0.9789156405018443,0.998223014412092,2.2518170558697803,1.9297833441110366,0.8704543213377697,-0.11355235818258648,0.28622861567613295,0.44001246034412966,-0.08621034266007742,-0.4455266972174347,-0.19697974106199748,2.7223660452457783,2.2641878529287944,-0.3409143906622731,0.007714294292187978,1.0269530506694047,1.3516408047634436,0.705432417367614,0.4284463495739996,0.474456483139522 | 2,948 |
Optic neuropathy | 10 | 22 | 3.175228 | 0.001497 | O96000,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q86Y39,P00846,Q9NPL8,Q9P0J0,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,37,135,8,44,77,14,240,86,95 | 8,839,339,1297,129,14,95,1825,2531,2799,2765,77,135,1789,665,44,240,441,1137,86,596,37 | 3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,1.9850015170325637,3.0256480119669416,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-1.2850028396706408,-1.1705743485850078,2.343244888252367,1.9506190541438213,-0.31162085873717893,0.5197985937189371,2.643303939387849,1.4933010900118375,0.9692152220740943,0.07317166718379643,2.258009524162855,0.662747577217144,2.7015163290761643 | 2,948 |
Cytochrome complex | 6 | 18 | 3.17437 | 0.001502 | O14949,P14406,P22695,Q9UDW1,P13073,P00403 | Localization | GO Cellular component | msigdb_gocc | 33,7,109,50,155,60 | 1000,448,33,60,809,1039,686,155,7,633,932,601,109,1441,858,174,50,720 | 0.15000139369493218,0.9399248957090145,2.737894239182016,2.5059894136062666,0.3223889389369212,0.12459546086867959,0.48585396547881715,1.8663245911664819,3.1028556423025955,0.5755625753080114,0.2126464378878266,0.6411810535042607,2.059171659276056,-0.12730986022355953,0.27408278382771123,1.772045557794017,2.6001384504964156,0.4630172524838215 | 2,948 |
Transmembrane transport | 113 | 213 | 3.167592 | 0.001537 | Q9NS69,P28288,Q07820,Q99595,P45880,P00846,P21796,Q9C0H2,P53007,Q9Y584,Q9H2D1,Q9HC07,Q9UHG3,O75844,O60830,Q9UDW1,O43772,O75298,P08195,Q9UBX3,Q07812,P00403,Q9Y4W6,P06576,Q70HW3,Q9BZF1,Q16625,Q8TB61,Q9HD20,Q8TAD4,O75964,O94826,Q6P4A7,P04062,P20674,Q8WTV0,P50416,P31751,P56134,Q8N4V1,O14925,P16615,Q15629,O60831,Q9Y619,O95202,P12236,P13073,Q9Y277,Q9NW15,Q13423,Q7KZN9,Q8IUH4,Q96QD8,Q6NT16,Q96GC9,P49755,Q9HC21,P24539,P23786,P30825,Q99623,Q6P4Q7,Q9BQT8,P52789,Q03519,O43615,P05023,L0R6Q1,P05141,P46934,Q96ES6,P56385,P27105,Q6NUK1,P19174,O75915,Q9H9B4,P08183,Q99442,Q4KMQ2,Q9BVC6,O95831,O00400,Q8IXU6,Q96NB2,O75027,Q9NY64,Q15043,P51790,O75381,Q99523,O43808,Q9UM00,P61619,Q02978,Q8NE86,P12235,Q8NE01,Q00325,Q9UGP8,O14548,O75746,Q9H2V7,P53985,P0CG08,Q3ZCQ8,Q04656,P05026,Q96AQ8,P20020,P23634,P35670 | Processes and pathways | GO Biological process | msigdb_gobp | 2,515,516,10,13,14,15,16,530,28,31,35,42,43,49,50,567,56,569,57,570,60,577,572,66,581,587,79,83,87,88,89,91,93,601,94,97,612,615,102,108,122,130,133,136,138,154,155,159,168,170,174,176,183,206,221,220,225,231,232,236,238,263,268,277,281,287,301,299,303,306,309,312,311,320,328,327,336,332,347,352,353,359,362,371,372,374,385,382,387,398,401,405,411,419,420,427,433,435,440,453,448,456,467,465,463,470,469,479,491,485,493,494 | 299,1605,2355,362,1000,448,108,287,1408,567,405,2155,2666,49,133,374,2622,839,56,398,2285,456,43,327,1774,88,89,138,1366,359,685,60,14,93,301,479,303,735,572,2132,1728,2784,2357,332,569,809,463,1777,686,1960,1556,433,154,155,122,810,328,485,601,1609,2792,2851,15,1299,493,232,231,1439,311,2880,2734,515,2532,2077,236,612,1441,769,494,2890,900,1442,2312,13,306,1731,858,2459,220,1559,97,1390,387,1707,277,530,465,1560,918,1159,615,312,1344,1734,1371,419,1146,1330,675,921,440,2121,420,281,469,1709,2854,1010,570,516,2243,1905,170,1737,2725,2516,950,1102,382,1103,1084,130,663,1246,587,1451,470,352,206,320,1309,91,263,1452,66,174,176,1334,371,1885,102,435,427,87,79,1541,94,1421,491,679,309,221,1423,372,850,183,347,2885,401,10,238,2894,740,1380,268,1694,353,581,16,2039,31,631,467,622,336,1293,35,225,83,705,2606,733,2,1834,168,385,57,50,453,2540,42,2450,652,1235,411,940,159,2426,838,577,28,136,2776 | 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| 2,948 |
Abnormality of the mitochondrion | 29 | 91 | 3.165444 | 0.001548 | O96000,Q8IUX1,O43676,P00846,P13073,Q9Y584,Q4J6C6,O75880,Q9Y6M9,P40939,Q96CU9,Q7KZN9,P12235,Q9NX14,Q00325,Q9UBX3,P00403,P21912,Q9Y2R0,Q70HW3,Q86Y39,P09622,O75306,Q3ZCQ8,Q9P0J0,P03886,P23786,Q9NPL8,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,135,8,14,155,28,162,288,37,426,44,174,433,441,440,57,60,188,61,66,77,337,339,470,86,95,232,240,379 | 782,807,1000,8,2677,567,721,839,339,1297,288,2542,129,60,14,95,1985,337,1872,1368,2380,433,155,2433,1825,601,188,2612,232,2383,2531,2661,1301,379,2408,1260,426,1849,2799,1119,1783,2765,1284,803,1100,1393,1328,2052,1563,440,2496,2441,508,1223,846,470,1416,162,1399,2816,1909,66,174,2320,2170,77,135,1789,1541,971,44,1352,1227,2501,2637,1694,478,2039,1211,240,441,1137,86,1836,57,61,596,1623,577,28,37 | 0.3581399659175588,0.3223889389369212,0.15000139369493218,3.0713505910312833,-0.9877958305297942,0.7160115787906041,0.451536002673528,0.28622861567613295,1.2295800256388367,-0.04562344444480704,1.3516408047634436,-0.8141766528354556,1.9850015170325637,2.5059894136062666,3.0256480119669416,2.1700017598173678,-0.43037928832775996,1.2384689484766933,-0.37046919446512544,-0.08621034266007742,-0.6813481805247098,0.9789156405018443,1.8663245911664819,-0.7140728496646459,-0.3409143906622731,0.6411810535042607,1.6897313558966025,-0.8998924548835083,1.5175956622312197,-0.6813481805247098,-0.7972875946120856,-0.9523656803307052,-0.04562344444480704,1.1115226986611575,-0.6976711102245209,-0.018844762829244025,0.998223014412092,-0.35565887677440616,-1.2850028396706408,0.07317166718379643,-0.31162085873717893,-1.1705743485850078,-0.032206450409452865,0.33435101991744987,0.08610500976236193,-0.09985266152283995,-0.05909615052808124,-0.46074315377249025,-0.18292663566061074,0.9692152220740943,-0.7637577132524961,-0.7140728496646459,0.8198384531051967,0.007714294292187978,0.28622861567613295,0.9103471386411612,-0.11355235818258648,1.8448473069506741,-0.09985266152283995,-1.323985431825699,-0.38534586462623527,2.4719430888618175,1.772045557794017,-0.6328456266009942,-0.5378809045039169,2.343244888252367,1.9506190541438213,-0.31162085873717893,-0.1689335436139936,0.18773580450914448,2.643303939387849,-0.07262497853037561,0.007714294292187978,-0.7637577132524961,-0.9172949987173196,-0.25380149284031334,0.8904664767159661,-0.4455266972174347,0.020912454144430923,1.4933010900118375,0.9692152220740943,0.07317166718379643,2.258009524162855,-0.3409143906622731,2.5617775528003315,2.500345305118897,0.662747577217144,-0.2110933158886262,0.705432417367614,2.794047586014273,2.7015163290761643 | 2,948 |
Sensorimotor neuropathy | 11 | 27 | 3.163103 | 0.001561 | P07602,O95831,Q5THJ4,P05023,P00846,O60313,Q9NZJ7,Q8N2K0,P00403,Q9Y2R0,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 324,359,203,301,14,219,189,250,60,61,95 | 807,693,219,359,60,14,95,301,324,2841,2046,426,1444,722,2052,1852,1565,1060,1514,889,203,250,1543,1108,189,61,577 | 0.3223889389369212,0.474456483139522,1.5813953757113124,1.1756765413677428,2.5059894136062666,3.0256480119669416,2.1700017598173678,1.325909696379107,1.2649757514469988,-1.4233578409590617,-0.46074315377249025,0.998223014412092,-0.12730986022355953,0.451536002673528,-0.46074315377249025,-0.35565887677440616,-0.18292663566061074,0.11181654260448975,-0.15500001376748473,0.2496506471199293,1.6360778607291422,1.4605868082268154,-0.1689335436139936,0.08610500976236193,1.6821282751850737,2.500345305118897,0.705432417367614 | 2,948 |
Proximal tubulopathy | 11 | 23 | 3.157806 | 0.00159 | O96000,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q86Y39,Q9NPL8,O75306,Q9NX14,P00403,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,37,135,8,44,77,240,339,441,60,95 | 8,839,339,1297,129,60,95,2433,1825,2531,1260,2765,1183,508,77,135,1789,44,240,441,1137,596,37 | 3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,1.9850015170325637,2.5059894136062666,2.1700017598173678,-0.7140728496646459,-0.3409143906622731,-0.7972875946120856,-0.018844762829244025,-1.1705743485850078,0.034056888274781295,0.8198384531051967,2.343244888252367,1.9506190541438213,-0.31162085873717893,2.643303939387849,1.4933010900118375,0.9692152220740943,0.07317166718379643,0.662747577217144,2.7015163290761643 | 2,948 |
Oxidoreduction driven active transmembrane transporter activity | 8 | 28 | 3.149458 | 0.001636 | O96000,Q9Y6M9,O43676,Q9UDW1,Q9P0J0,P13073,P00403,P03886 | Functions | GO Molecular function | msigdb_gomf | 129,37,8,50,86,155,60,95 | 1000,448,8,839,339,1297,2095,2335,2542,129,60,95,809,686,155,1825,601,2531,1441,858,2765,803,1373,1223,174,86,50,37 | 0.15000139369493218,0.9399248957090145,3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.5059894136062666,2.1700017598173678,0.3223889389369212,0.48585396547881715,1.8663245911664819,-0.3409143906622731,0.6411810535042607,-0.7972875946120856,-0.12730986022355953,0.27408278382771123,-1.1705743485850078,0.33435101991744987,-0.08621034266007742,0.007714294292187978,1.772045557794017,2.258009524162855,2.6001384504964156,2.7015163290761643 | 2,948 |
Azurophil granule membrane | 10 | 18 | 3.149341 | 0.001636 | P10253,P07602,Q92542,Q8NF37,Q9NQX7,O15260,P42785,Q9NZJ7,P27105,Q07065 | Localization | GO Cellular component | msigdb_gocc | 325,324,295,107,245,369,146,189,311,124 | 369,2256,1524,324,325,438,311,1626,146,1327,659,124,847,107,295,1891,245,189 | 1.1483517684971725,-0.6008926353532796,-0.1689335436139936,1.2649757514469988,1.2649757514469988,0.9692152220740943,1.2825150544453023,-0.22526782119676403,1.9017575126557482,-0.05909615052808124,0.5310317416999976,2.012203505380641,0.28622861567613295,2.065816515305065,1.3345119408817352,-0.37046919446512544,1.4769902629485032,1.6821282751850737 | 2,948 |
Lipid droplet | 12 | 31 | 3.145641 | 0.001657 | P09455,Q96RL7,O43760,Q9Y679,Q96CS3,Q8NF37,P51572,Q99720,Q8NBQ5,Q9H6V9,Q07065,Q01105 | Localization | GO Cellular component | msigdb_gocc | 480,383,160,492,428,107,396,21,406,120,124,447 | 2489,160,1773,865,1003,944,2378,2132,480,946,1327,833,396,2052,447,124,1062,1064,1030,406,490,107,1151,428,383,21,1292,120,851,2152,492 | -0.7637577132524961,1.8448473069506741,-0.31162085873717893,0.26189023374501835,0.15000139369493218,0.2002154590345209,-0.6813481805247098,-0.5223107110430917,0.8804769315934403,0.2002154590345209,-0.05909615052808124,0.2983280445189644,1.0648357439505178,-0.46074315377249025,0.9497200302794863,2.012203505380641,0.11181654260448975,0.11181654260448975,0.13732362625944375,1.0364688150319994,0.8704543213377697,2.065816515305065,0.060186115633053816,0.998223014412092,1.1022436718162008,2.936470354523948,-0.032206450409452865,2.032430731714956,0.28622861567613295,-0.5223107110430917,0.8704543213377697 | 2,948 |
Huntingtons disease | 17 | 74 | 3.141144 | 0.001683 | O96000,O14949,Q9Y6M9,P14406,O43676,P24539,P45880,P00846,P21796,P05141,P00403,Q9UDW1,P22695,P12236,P13073,P21912,Q9Y277 | Processes and pathways | KEGG Pathways | msigdb_kegg | 129,33,37,7,8,231,13,14,15,303,60,50,109,154,155,188,159 | 1000,448,33,8,839,339,1297,1774,2679,2095,2335,2542,2429,129,60,14,2430,1526,303,572,809,1257,1039,686,433,154,155,7,633,932,1411,810,1873,1825,601,15,188,109,231,2660,1439,2880,2531,899,1301,1441,900,963,13,858,2459,2765,803,1507,2313,2821,1121,1994,1903,2587,570,676,594,538,1476,1103,1373,1223,2127,983,50,1603,159,37 | 0.15000139369493218,0.9399248957090145,2.737894239182016,3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.31162085873717893,-0.9877958305297942,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,-0.7140728496646459,1.9850015170325637,2.5059894136062666,3.0256480119669416,-0.7140728496646459,-0.1689335436139936,1.3172820683611308,0.705432417367614,0.3223889389369212,-0.018844762829244025,0.12459546086867959,0.48585396547881715,0.9789156405018443,1.873447213431415,1.8663245911664819,3.1028556423025955,0.5755625753080114,0.2126464378878266,-0.11355235818258648,0.3223889389369212,-0.37046919446512544,-0.3409143906622731,0.6411810535042607,3.021031890458238,1.6897313558966025,2.059171659276056,1.525648527311823,-0.9523656803307052,-0.12730986022355953,-1.6095037071757186,-0.7972875946120856,0.23736370252558897,-0.04562344444480704,-0.12730986022355953,0.23736370252558897,0.18773580450914448,3.03485502403842,0.27408278382771123,-0.7305540733601957,-1.1705743485850078,0.33435101991744987,-0.15500001376748473,-0.6328456266009942,-1.3436388023652246,0.07317166718379643,-0.43037928832775996,-0.38534586462623527,-0.8653490426838603,0.7160115787906041,0.4972099678438886,0.662747577217144,0.7579666967264426,-0.14112559981342382,0.08610500976236193,-0.08621034266007742,0.007714294292187978,-0.5068124202196339,0.17520713667950955,2.6001384504964156,-0.19697974106199748,1.8520247203194133,2.7015163290761643 | 2,948 |
Amyloid precursor protein metabolic process | 8 | 23 | 3.140263 | 0.001688 | P35610,Q15392,Q16799,Q9NQC3,Q9NQX7,O75298,P49755,O95197 | Processes and pathways | GO Biological process | msigdb_gobp | 224,134,12,46,245,56,220,30 | 1463,56,30,1555,2880,224,963,220,1559,1330,2341,2562,1305,967,134,12,295,953,574,2222,46,245,1018 | -0.14112559981342382,2.5617775528003315,2.7686743452412657,-0.18292663566061074,-1.6095037071757186,1.5655779034583233,0.18773580450914448,1.5813953757113124,-0.18292663566061074,-0.05909615052808124,-0.6489360930417204,-0.8311494216532105,-0.04562344444480704,0.18773580450914448,1.957529717511198,3.0394459686419903,1.3345119408817352,0.2002154590345209,0.705432417367614,-0.5692393713422798,2.6379469928697454,1.4769902629485032,0.15000139369493218 | 2,948 |
Abnormal csf metabolite level | 16 | 54 | 3.14 | 0.001689 | O96000,Q9HC21,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q7KZN9,P00846,Q86Y39,Q9NPL8,O75306,Q9P0J0,Q9NWS8,P13073,P00403,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,225,37,135,8,44,174,14,77,240,339,86,248,155,60,95 | 782,1000,694,8,582,839,339,1297,2570,2542,359,129,60,14,95,1985,155,1825,2531,2661,1301,1875,2700,1849,2765,1756,803,1393,902,1612,1536,2441,1223,620,174,1658,77,135,1789,2899,558,1541,44,1227,2501,1694,225,240,248,441,1137,86,596,37 | 0.3581399659175588,0.15000139369493218,0.474456483139522,3.0713505910312833,0.6841640874618475,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.8482066366426134,-0.8141766528354556,1.1756765413677428,1.9850015170325637,2.5059894136062666,3.0256480119669416,2.1700017598173678,-0.43037928832775996,1.8663245911664819,-0.3409143906622731,-0.7972875946120856,-0.9523656803307052,-0.04562344444480704,-0.37046919446512544,-1.0235920080980971,-0.35565887677440616,-1.1705743485850078,-0.29707080001748704,0.33435101991744987,-0.09985266152283995,0.23736370252558897,-0.2110933158886262,-0.1689335436139936,-0.7140728496646459,0.007714294292187978,0.6085459020758718,1.772045557794017,-0.23950372309971943,2.343244888252367,1.9506190541438213,-0.31162085873717893,-1.850858038664009,0.7370610056166005,-0.1689335436139936,2.643303939387849,0.007714294292187978,-0.7637577132524961,-0.25380149284031334,1.5655779034583233,1.4933010900118375,1.4688001720482913,0.9692152220740943,0.07317166718379643,2.258009524162855,0.662747577217144,2.7015163290761643 | 2,948 |
Abnormal circulating lipid concentration | 32 | 72 | 3.128267 | 0.001758 | Q15392,Q9UJS0,P40855,O75845,O75381,P06280,O75880,Q15800,P40939,O75844,O43772,Q9NZJ7,Q8N511,O95470,Q9NVI7,P50402,P07602,Q15904,Q969N2,P09622,P37268,Q9UBM7,O75431,P50416,P31751,P23786,P49257,P35573,Q14739,Q9Y4P3,P22830,P16219 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 134,652,395,137,398,668,288,34,426,43,567,189,63,64,322,195,324,329,588,337,468,343,223,97,612,232,361,500,118,249,635,634 | 1722,1408,2403,567,398,223,43,137,288,64,868,668,2157,324,337,2380,634,635,232,1961,802,612,2916,842,500,2408,468,2819,395,426,2262,361,1783,195,97,2735,722,2412,1852,936,688,1965,1183,777,824,1613,2516,118,845,134,1064,34,329,846,1416,63,1350,1543,588,1890,2273,1211,2425,322,189,343,1458,652,1138,249,790,1434 | -0.2825845468972897,-0.11355235818258648,-0.6976711102245209,0.7160115787906041,1.0554099937856247,1.5655779034583233,2.643303939387849,1.9436911549131641,1.3516408047634436,2.4776479082465204,0.26189023374501835,0.5085247561108027,-0.5378809045039169,1.2649757514469988,1.2384689484766933,-0.6813481805247098,0.5755625753080114,0.5755625753080114,1.5175956622312197,-0.4153003756640121,0.33435101991744987,0.6194626505037427,-2.133625916476744,0.28622861567613295,0.8503091286584517,-0.6976711102245209,0.9103471386411612,-1.3436388023652246,1.0648357439505178,0.998223014412092,-0.6008926353532796,1.1756765413677428,-0.31162085873717893,1.6591962119392685,2.137867848356007,-1.077987350196644,0.451536002673528,-0.6976711102245209,-0.35565887677440616,0.2126464378878266,0.48585396547881715,-0.4153003756640121,0.034056888274781295,0.36996742888124223,0.3103813825441349,-0.2110933158886262,-0.780481520558001,2.032430731714956,0.28622861567613295,1.957529717511198,0.11181654260448975,2.737894239182016,1.2561666700159204,0.28622861567613295,-0.11355235818258648,2.4946891459781244,-0.07262497853037561,-0.1689335436139936,0.6734744686950634,-0.37046919446512544,-0.6008926353532796,0.020912454144430923,-0.6976711102245209,1.2737585000217826,1.6821282751850737,1.2206642044639127,-0.12730986022355953,0.553377001040428,0.07317166718379643,1.4688001720482913,0.3581399659175588,-0.11355235818258648 | 2,948 |
Abnormality of hepatobiliary system physiology | 32 | 75 | 3.120843 | 0.001803 | P28288,Q9Y619,P40855,O75845,O75381,P00846,Q96A33,Q5XKP0,O15118,P40939,O43772,O75787,Q8N511,A2RRP1,O43819,Q16625,Q9BT22,Q8TCJ2,P09622,O75306,Q13510,Q13043,P04062,P03886,P50416,P23786,Q10713,P22695,P35670,P01889,Q9NWS8,Q6PGP7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 515,136,395,137,398,14,143,279,151,426,567,443,63,323,582,587,76,335,337,339,84,598,93,95,97,232,233,109,494,614,248,126 | 323,151,773,2677,567,582,1671,339,398,443,137,2111,14,614,95,93,1498,1649,809,337,2380,2113,1874,109,635,232,515,2878,494,2408,2510,2819,1626,395,426,2410,1849,97,1733,1852,2923,2722,1903,233,598,84,1513,923,587,1247,846,279,672,126,1658,63,335,1541,143,1227,76,1211,2425,2067,1747,248,2328,1665,1717,1234,720,1092,1623,790,136 | 1.2649757514469988,1.8947068052131284,0.36996742888124223,-0.9877958305297942,0.7160115787906041,0.6841640874618475,-0.25380149284031334,1.2295800256388367,1.0554099937856247,0.9594834119537029,1.9436911549131641,-0.5068124202196339,3.0256480119669416,0.6085459020758718,2.1700017598173678,2.182750080789599,-0.15500001376748473,-0.23950372309971943,0.3223889389369212,1.2384689484766933,-0.6813481805247098,-0.5068124202196339,-0.37046919446512544,2.059171659276056,0.5755625753080114,1.5175956622312197,0.7993537399833668,-1.5883383065270185,0.8603984521649488,-0.6976711102245209,-0.780481520558001,-1.3436388023652246,-0.22526782119676403,1.0648357439505178,0.998223014412092,-0.6976711102245209,-0.35565887677440616,2.137867848356007,-0.2825845468972897,-0.35565887677440616,-2.466222875172167,-1.0597609447700629,-0.38534586462623527,1.5175956622312197,0.6519831828829221,2.258009524162855,-0.15500001376748473,0.22502907537646621,0.6734744686950634,-0.005537980331740621,0.28622861567613295,1.3771469826873006,0.5085247561108027,2.012203505380641,-0.23950372309971943,2.4946891459781244,1.247331115968002,-0.1689335436139936,1.9297833441110366,0.007714294292187978,2.3611636015336126,0.020912454144430923,-0.6976711102245209,-0.46074315377249025,-0.2825845468972897,1.4688001720482913,-0.6328456266009942,-0.23950372309971943,-0.26816160686466817,0.007714294292187978,0.4630172524838215,0.09898651295405862,-0.2110933158886262,0.3581399659175588,1.9506190541438213 | 2,948 |
Retrograde vesicle mediated transport golgi to endoplasmic reticulum | 14 | 29 | 3.114257 | 0.001844 | O75396,O15258,Q96RQ1,O43731,A2RRP1,Q9P2W9,P24390,Q8TD16,Q9H082,Q12981,Q12907,Q9Y282,P49755,Q9H4A6 | Processes and pathways | GO Biological process | msigdb_gobp | 514,286,228,5,323,40,11,461,528,273,557,52,220,384 | 323,2012,286,566,5,514,2233,11,1781,1240,1651,220,2439,872,557,273,672,461,1863,1151,906,228,528,772,384,2425,40,2199,52 | 1.2649757514469988,-0.4455266972174347,1.3516408047634436,0.7160115787906041,3.16470177536829,0.7993537399833668,-0.5850288483198346,3.044028574777508,-0.31162085873717893,-0.005537980331740621,-0.23950372309971943,1.5813953757113124,-0.7140728496646459,0.26189023374501835,0.7370610056166005,1.3855996558557733,0.5085247561108027,0.9300978254026866,-0.35565887677440616,0.060186115633053816,0.23736370252558897,1.5496727044793,0.7787303765438011,0.3817506123919569,1.1022436718162008,-0.6976711102245209,2.664622633709218,-0.5535235918543128,2.5892351771566373 | 2,948 |
Alzheimers disease | 14 | 58 | 3.110414 | 0.001868 | O96000,O14949,Q9Y6M9,P14406,O43676,Q92542,P24539,P22695,P00846,P00403,Q9UDW1,P16615,P13073,P21912 | Processes and pathways | KEGG Pathways | msigdb_kegg | 129,33,37,7,8,295,231,109,14,60,50,122,155,188 | 1174,1000,448,33,8,839,339,1297,1774,2095,2335,2542,129,60,14,2378,572,1728,809,1039,1777,686,155,7,2572,633,932,122,2659,810,1825,601,188,109,231,1439,2288,2531,2309,1301,1441,900,963,858,2459,1802,2765,1732,803,2121,2166,1373,1223,295,2501,50,2540,37 | 0.034056888274781295,0.15000139369493218,0.9399248957090145,2.737894239182016,3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.31162085873717893,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.5059894136062666,3.0256480119669416,-0.6813481805247098,0.705432417367614,-0.2825845468972897,0.3223889389369212,0.12459546086867959,-0.31162085873717893,0.48585396547881715,1.8663245911664819,3.1028556423025955,-0.8482066366426134,0.5755625753080114,0.2126464378878266,2.0189623913532273,-0.9523656803307052,0.3223889389369212,-0.3409143906622731,0.6411810535042607,1.6897313558966025,2.059171659276056,1.525648527311823,-0.12730986022355953,-0.6168313523355917,-0.7972875946120856,-0.6328456266009942,-0.04562344444480704,-0.12730986022355953,0.23736370252558897,0.18773580450914448,0.27408278382771123,-0.7305540733601957,-0.3262352210800657,-1.1705743485850078,-0.2825845468972897,0.33435101991744987,-0.5068124202196339,-0.5378809045039169,-0.08621034266007742,0.007714294292187978,1.3345119408817352,-0.7637577132524961,2.6001384504964156,-0.7972875946120856,2.7015163290761643 | 2,948 |
Ion transmembrane transport | 75 | 158 | 3.105273 | 0.001901 | Q15043,P51790,O60831,Q6P4Q7,Q9Y619,O95202,Q9BQT8,P45880,P00846,P21796,Q9C0H2,O43808,P53007,P12236,P13073,Q9UM00,Q9H2D1,Q9Y277,Q9HC07,P61619,Q02978,Q9NW15,Q8NE86,Q9UHG3,O75844,Q13423,Q7KZN9,P05023,P05141,Q8IUH4,P12235,Q9UDW1,P46934,Q96ES6,O43772,Q00325,P08195,Q07812,Q9UBX3,P00403,Q9Y4W6,P56385,P27105,Q70HW3,O14548,P19174,O75746,O75915,Q9H9B4,Q8TB61,P08183,P53985,P0CG08,Q9HD20,Q8TAD4,O75964,Q04656,Q96GC9,Q6P4A7,P05026,Q4KMQ2,Q9HC21,Q9BVC6,Q96AQ8,Q8N4V1,P24539,O00400,P30825,P20020,P23634,Q99623,P35670,Q96NB2,O75027,P16615 | Processes and pathways | GO Biological process | msigdb_gobp | 382,387,133,263,136,138,268,13,14,15,16,405,530,154,155,411,31,159,35,419,420,168,427,42,43,170,174,301,303,176,433,50,306,309,567,440,569,570,57,60,577,312,311,66,448,328,456,327,336,79,332,465,463,83,87,88,469,221,91,479,352,225,353,491,102,231,362,236,485,493,238,494,372,374,122 | 2355,362,1000,448,1408,567,405,2155,2666,133,374,2622,839,2285,456,43,327,1774,88,138,1366,60,14,301,479,303,735,572,2132,1728,2357,332,569,809,463,1777,686,1556,433,154,155,122,810,328,485,601,1609,2792,2851,15,493,231,1439,311,2880,2734,2532,2077,236,1441,494,2890,900,1442,2312,13,306,1731,858,2459,1390,387,1707,530,465,1560,918,1159,615,312,1371,419,1146,1330,675,921,440,2121,420,469,1709,1010,570,2243,1905,170,1737,2725,2516,950,1102,382,1103,663,352,91,263,66,174,176,1334,1885,102,427,87,79,1421,491,679,309,221,1423,372,850,2885,238,2894,1380,268,1694,353,16,2039,31,622,336,35,225,83,705,2606,1834,168,57,50,2540,42,2450,652,1235,411,940,159,2426,838,577,136,2776 | -0.6651033942270582,1.1665962650895083,0.15000139369493218,0.9399248957090145,-0.11355235818258648,0.7160115787906041,1.0364688150319994,-0.5378809045039169,-0.9700354159181358,1.957529717511198,1.1299943266097154,-0.9172949987173196,0.28622861567613295,-0.6168313523355917,0.9300978254026866,2.643303939387849,1.2561666700159204,-0.31162085873717893,2.233154239652949,1.9436911549131641,-0.08621034266007742,2.5059894136062666,3.0256480119669416,1.325909696379107,0.8804769315934403,1.3172820683611308,0.4284463495739996,0.705432417367614,-0.5223107110430917,-0.2825845468972897,-0.6651033942270582,1.247331115968002,0.7160115787906041,0.3223889389369212,0.9202386350075965,-0.31162085873717893,0.48585396547881715,-0.18292663566061074,0.9789156405018443,1.873447213431415,1.8663245911664819,2.0189623913532273,0.3223889389369212,1.2561666700159204,0.8704543213377697,0.6411810535042607,-0.2110933158886262,-1.2656715296047802,-1.4435695136020075,3.021031890458238,0.8603984521649488,1.525648527311823,-0.12730986022355953,1.2825150544453023,-1.6095037071757186,-1.077987350196644,-0.7972875946120856,-0.4760292158199211,1.509520209213793,-0.12730986022355953,0.8603984521649488,-1.71722930421042,0.23736370252558897,-0.12730986022355953,-0.6328456266009942,3.03485502403842,1.3086289242426126,-0.2825845468972897,0.27408278382771123,-0.7305540733601957,-0.09985266152283995,1.0929356242486823,-0.26816160686466817,0.7683661814306533,0.9202386350075965,-0.18292663566061074,0.22502907537646621,0.047147981735179874,0.6085459020758718,1.2825150544453023,-0.08621034266007742,1.007830322351225,0.060186115633053816,-0.05909615052808124,0.4972099678438886,0.22502907537646621,0.9692152220740943,-0.5068124202196339,1.007830322351225,0.9103471386411612,-0.26816160686466817,0.15000139369493218,0.7160115787906041,-0.5850288483198346,-0.38534586462623527,1.808682116385517,-0.2825845468972897,-1.0597609447700629,-0.780481520558001,0.2002154590345209,0.08610500976236193,1.1022436718162008,0.08610500976236193,0.5197985937189371,1.1937539044717103,2.1954390050858774,1.4274982699452592,2.4719430888618175,1.772045557794017,1.757256508499432,-0.05909615052808124,-0.37046919446512544,2.111885928965945,0.998223014412092,2.2518170558697803,2.325205828646418,-0.11355235818258648,0.8704543213377697,0.4972099678438886,1.2999501304431609,1.5813953757113124,-0.11355235818258648,1.1483517684971725,0.28622861567613295,-1.6307939198566663,1.5014220561203693,-1.7612307722767848,-0.08621034266007742,1.4108112793572933,-0.25380149284031334,1.1937539044717103,3.021031890458238,-0.4455266972174347,2.7635696710490953,0.6085459020758718,1.247331115968002,2.7223660452457783,1.5655779034583233,2.2641878529287944,0.474456483139522,-0.8825773941139174,-0.3409143906622731,1.8304371083321016,2.5617775528003315,2.6001384504964156,-0.7972875946120856,2.648649937374481,-0.7140728496646459,0.553377001040428,0.007714294292187978,1.0269530506694047,0.2126464378878266,1.8520247203194133,-0.6976711102245209,0.2983280445189644,0.705432417367614,1.9506190541438213,-1.1705743485850078 | 2,948 |
Glycosylation | 17 | 38 | 3.090173 | 0.002 | Q9HC07,Q6ZXV5,Q8N4A0,O60762,P04843,Q9BT22,Q8TCJ2,O43505,Q10472,P46977,Q2TAA5,O15118,O60502,Q9NYU2,P04062,Q96AA3,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 35,517,70,545,457,76,335,235,207,110,366,151,275,217,93,186,191 | 151,2332,235,275,545,1410,881,191,2680,93,457,1074,556,1626,110,1180,1266,1760,748,824,207,737,366,517,1149,70,2029,335,186,76,1068,2425,2447,35,2326,217,2540,2488 | 1.8947068052131284,-0.6489360930417204,1.509520209213793,1.3771469826873006,0.7475317096601524,-0.11355235818258648,0.2496506471199293,1.674504789012511,-0.9877958305297942,2.182750080789599,0.9300978254026866,0.09898651295405862,0.7370610056166005,-0.22526782119676403,2.059171659276056,0.034056888274781295,-0.018844762829244025,-0.29707080001748704,0.41683739185316737,0.3103813825441349,1.612770532132464,0.4284463495739996,1.1574880581635068,0.7993537399833668,0.060186115633053816,2.41421165375674,-0.4455266972174347,1.247331115968002,1.7124191246748732,2.3611636015336126,0.11181654260448975,-0.6976711102245209,-0.7140728496646459,2.7223660452457783,-0.6328456266009942,1.5892714807064798,-0.7972875946120856,-0.7471154641344182 | 2,948 |
Cardiac muscle contraction | 9 | 22 | 3.089345 | 0.002006 | O14949,O14548,P14406,P05023,P22695,Q9UDW1,P16615,P13073,P00403 | Processes and pathways | KEGG Pathways | msigdb_kegg | 33,448,7,301,109,50,122,155,60 | 448,33,60,301,479,1776,809,756,1039,686,155,7,633,932,122,601,109,1441,858,918,1964,50 | 0.9399248957090145,2.737894239182016,2.5059894136062666,1.325909696379107,0.8804769315934403,-0.31162085873717893,0.3223889389369212,0.4051853060515837,0.12459546086867959,0.48585396547881715,1.8663245911664819,3.1028556423025955,0.5755625753080114,0.2126464378878266,2.0189623913532273,0.6411810535042607,2.059171659276056,-0.12730986022355953,0.27408278382771123,0.22502907537646621,-0.4153003756640121,2.6001384504964156 | 2,948 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 11 | 26 | 3.082103 | 0.002055 | Q15800,P16435,P30519,Q14534,O75845,P61457,Q6UW02,O00767,Q8NB78,Q16850,P09601 | Functions | GO Molecular function | msigdb_gomf | 34,200,9,75,137,363,175,338,114,185,29 | 338,773,2825,1955,137,378,568,29,669,200,9,363,1266,887,75,34,185,664,1570,175,2477,114,1864,2064,552,741 | 1.2295800256388367,0.36996742888124223,-1.3634016393857866,-0.4153003756640121,1.9436911549131641,1.1115226986611575,0.7160115787906041,2.773768964357425,0.5085247561108027,1.643804841337337,3.0668174590396893,1.1665962650895083,-0.018844762829244025,0.2496506471199293,2.3611636015336126,2.737894239182016,1.7124191246748732,0.5197985937189371,-0.18292663566061074,1.7646607238274559,-0.7471154641344182,2.0458336345454717,-0.35565887677440616,-0.46074315377249025,0.7475317096601524,0.4284463495739996 | 2,948 |
Passive transmembrane transporter activity | 19 | 37 | 3.044688 | 0.002329 | P51790,P45880,P00846,P21796,Q9C0H2,Q9UM00,Q9Y277,P61619,Q9NW15,Q8NE86,Q07812,P56385,P06576,P0CG08,O75964,Q4KMQ2,Q9BVC6,P24539,Q96S66 | Functions | GO Molecular function | msigdb_gomf | 387,13,14,15,16,411,159,419,168,427,570,312,572,463,88,352,353,231,253 | 2355,1774,88,685,14,572,2132,2357,463,810,15,231,1439,900,2312,13,2459,387,1707,615,312,419,2121,570,352,427,1421,679,253,740,353,16,1834,168,411,159,2776 | -0.6651033942270582,-0.31162085873717893,2.233154239652949,0.48585396547881715,3.0256480119669416,0.705432417367614,-0.5223107110430917,-0.6651033942270582,0.9202386350075965,0.3223889389369212,3.021031890458238,1.525648527311823,-0.12730986022355953,0.23736370252558897,-0.6328456266009942,3.03485502403842,-0.7305540733601957,1.0929356242486823,-0.26816160686466817,0.6085459020758718,1.2825150544453023,1.007830322351225,-0.5068124202196339,0.7160115787906041,1.1937539044717103,0.998223014412092,-0.11355235818258648,0.4972099678438886,1.4523500544317842,0.4284463495739996,1.1937539044717103,3.021031890458238,-0.3409143906622731,1.8304371083321016,1.0269530506694047,1.8520247203194133,-1.1705743485850078 | 2,948 |
Ion channel transport | 15 | 33 | 3.041806 | 0.002352 | Q4KMQ2,P51790,Q9NW15,Q15904,P20020,P05023,P23634,Q93050,Q9C0H2,Q9HD20,Q04656,P16615,P27105,Q9Y487,P05026 | Processes and pathways | Reactome Pathways | msigdb_reactome | 352,387,168,329,485,301,493,142,16,83,469,122,311,292,479 | 301,479,122,485,1609,2792,493,311,2077,494,1442,2312,387,1707,918,1371,921,469,887,1737,1762,2725,329,352,142,850,891,16,83,168,2450,292,1770 | 1.325909696379107,0.8804769315934403,2.0189623913532273,0.8704543213377697,-0.2110933158886262,-1.2656715296047802,0.8603984521649488,1.2825150544453023,-0.4760292158199211,0.8603984521649488,-0.12730986022355953,-0.6328456266009942,1.0929356242486823,-0.26816160686466817,0.22502907537646621,-0.08621034266007742,0.22502907537646621,0.9103471386411612,0.2496506471199293,-0.2825845468972897,-0.29707080001748704,-1.0597609447700629,1.2561666700159204,1.1937539044717103,1.9297833441110366,0.28622861567613295,0.2496506471199293,3.021031890458238,2.2641878529287944,1.8304371083321016,-0.7140728496646459,1.3516408047634436,-0.29707080001748704 | 2,948 |
Ceramide metabolic process | 14 | 18 | 3.035138 | 0.002404 | O95470,P06280,Q9NXE4,P27544,Q99805,Q96G23,Q13510,P04062,P17900,Q8NCC3,Q53H12,O43464,Q9HA82,O15269 | Processes and pathways | GO Biological process | msigdb_gobp | 64,668,643,229,267,47,84,93,145,121,539,694,512,474 | 474,693,694,64,93,668,1038,2528,145,229,1530,84,539,121,47,267,512,643 | 0.8904664767159661,0.474456483139522,0.474456483139522,2.4776479082465204,2.182750080789599,0.5085247561108027,0.12459546086867959,-0.7972875946120856,1.9017575126557482,1.5416869382636196,-0.1689335436139936,2.258009524162855,0.7579666967264426,2.025704776459826,2.6272000953809203,1.4191667686938891,0.8096133248148545,0.5644896226799964 | 2,948 |
Sterol metabolic process | 13 | 36 | 3.021965 | 0.002511 | Q15800,Q9BQE5,P04035,Q15392,P16435,Q14849,Q14534,O75845,Q14739,O15118,Q16850,P04062,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 34,4,100,134,200,104,75,137,118,151,185,93,94 | 151,137,942,944,100,93,1556,1625,200,2612,2916,224,468,2819,2583,946,1783,2292,975,688,2314,2842,1448,2758,75,118,104,2835,134,1064,34,185,94,4,343,1318 | 1.8947068052131284,1.9436911549131641,0.2002154590345209,0.2002154590345209,2.111885928965945,2.182750080789599,-0.18292663566061074,-0.22526782119676403,1.643804841337337,-0.8998924548835083,-2.133625916476744,1.5655779034583233,0.9103471386411612,-1.3436388023652246,-0.8653490426838603,0.2002154590345209,-0.31162085873717893,-0.6168313523355917,0.17520713667950955,0.48585396547881715,-0.6328456266009942,-1.4233578409590617,-0.12730986022355953,-1.151859916150363,2.3611636015336126,2.032430731714956,2.105351748565537,-1.3832750243291831,1.957529717511198,0.11181654260448975,2.737894239182016,1.7124191246748732,2.176383375551823,3.190745333119537,1.2206642044639127,-0.04562344444480704 | 2,948 |
Glycosyltransferase | 9 | 15 | 3.016261 | 0.002559 | Q8N4A0,P04843,Q9BT22,Q8TCJ2,P46977,Q10472,P35573,Q8N128,Q9NYU2 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 70,457,76,335,110,207,500,85,217 | 545,457,1074,500,1626,1119,110,1180,824,207,85,70,335,76,217 | 0.7475317096601524,0.9300978254026866,0.09898651295405862,0.8503091286584517,-0.22526782119676403,0.07317166718379643,2.059171659276056,0.034056888274781295,0.3103813825441349,1.612770532132464,2.258009524162855,2.41421165375674,1.247331115968002,2.3611636015336126,1.5892714807064798 | 2,948 |
Left ventricular hypertrophy | 10 | 23 | 3.014608 | 0.002573 | Q6NUK1,O75880,O75208,P10253,O75431,P40939,P00403,P12235,P21912,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 320,288,381,325,223,426,60,433,188,95 | 1196,381,223,443,288,60,95,668,325,433,1324,188,1301,426,1852,731,737,750,320,1658,2170,971,2447 | 0.020912454144430923,1.1022436718162008,1.5655779034583233,0.9594834119537029,1.3516408047634436,2.5059894136062666,2.1700017598173678,0.5085247561108027,1.2649757514469988,0.9789156405018443,-0.05909615052808124,1.6897313558966025,-0.04562344444480704,0.998223014412092,-0.35565887677440616,0.44001246034412966,0.4284463495739996,0.41683739185316737,1.2737585000217826,-0.23950372309971943,-0.5378809045039169,0.18773580450914448,-0.7140728496646459 | 2,948 |
Golgi membrane | 59 | 132 | 3.013851 | 0.00258 | O75396,P51790,Q7LGA3,Q7Z3C6,O43731,Q15392,O14617,P24390,Q16799,P61026,P51572,Q9H082,Q8NBN3,Q9UM00,Q92896,O95197,Q9Y3E0,P61019,Q9HC07,O15258,Q9P2W9,P33908,O43752,L0R6Q1,Q8NCH0,Q12907,Q8IUH4,Q15363,Q9Y282,O60499,Q14108,Q99640,P35613,Q9Y3B3,Q8N4A0,O00461,Q8TBA6,Q8TB61,Q10472,Q9BUR5,P0CG08,P49755,P04439,Q9H7Z7,Q9NTJ5,Q8N4V1,Q10713,P49257,Q8NF37,O43505,O00400,Q14789,P35670,Q13190,O15260,O95070,Q96S66,Q9H4A6,Q8IV08 | Localization | GO Cellular component | msigdb_gocc | 514,387,260,518,5,134,389,11,12,269,396,528,25,411,540,30,543,413,35,286,40,556,171,299,48,557,176,177,52,53,54,315,439,190,70,74,331,79,207,81,463,220,475,354,356,102,233,361,107,235,362,487,494,495,369,116,253,384,255 | 299,362,74,2012,389,854,286,369,783,566,235,2201,5,2129,171,53,1646,514,116,30,2110,614,475,1202,463,658,1076,1280,11,556,1781,439,494,2764,1369,1204,1240,1651,361,220,1390,935,396,387,793,2866,2787,2439,2646,2757,2494,2751,413,269,804,872,1242,764,921,2901,748,824,207,2140,233,557,495,2341,54,487,2390,1103,177,134,1515,12,2876,260,518,2220,605,1520,176,255,1270,70,102,701,25,48,107,79,331,1863,1151,540,906,2893,253,315,81,829,1950,1428,528,1034,772,384,354,2892,2425,2447,35,705,356,643,40,2199,2200,2540,2009,706,411,52,1018,1521,2847,742,190,543,2011,1387 | 1.325909696379107,1.1665962650895083,2.3611636015336126,-0.4455266972174347,1.0835983952732648,0.27408278382771123,1.3516408047634436,1.1483517684971725,0.3581399659175588,0.7160115787906041,1.509520209213793,-0.5692393713422798,3.16470177536829,-0.5223107110430917,1.8013928596418074,2.572795002492806,-0.23950372309971943,0.7993537399833668,2.0391403276957534,2.7686743452412657,-0.5068124202196339,0.6085459020758718,0.8904664767159661,0.020912454144430923,0.9202386350075965,0.5310317416999976,0.09898651295405862,-0.032206450409452865,3.044028574777508,0.7370610056166005,-0.31162085873717893,0.9692152220740943,0.8603984521649488,-1.1705743485850078,-0.08621034266007742,0.020912454144430923,-0.005537980331740621,-0.23950372309971943,1.1756765413677428,1.5813953757113124,-0.09985266152283995,0.2126464378878266,1.0648357439505178,1.0929356242486823,0.34626792877763996,-1.5048993761550162,-1.2273237680303433,-0.7140728496646459,-0.9347858092775326,-1.151859916150363,-0.7637577132524961,-1.133244923304272,1.017406943541416,1.4024316796859169,0.33435101991744987,0.26189023374501835,-0.005537980331740621,0.393489808386937,0.22502907537646621,-1.8965076209613505,0.41683739185316737,0.3103813825441349,1.612770532132464,-0.5223107110430917,1.5175956622312197,0.7370610056166005,0.8603984521649488,-0.6489360930417204,2.572795002492806,0.8704543213377697,-0.6813481805247098,0.08610500976236193,1.7349266711727922,1.957529717511198,-0.15500001376748473,3.0394459686419903,-1.5672964314174564,1.4358059044741707,0.7993537399833668,-0.5692393713422798,0.6411810535042607,-0.15500001376748473,1.757256508499432,1.444089792764959,-0.018844762829244025,2.41421165375674,2.111885928965945,0.474456483139522,2.8141680896618446,2.6109966368519584,2.065816515305065,2.325205828646418,1.2561666700159204,-0.35565887677440616,0.060186115633053816,0.7579666967264426,0.23736370252558897,-1.7391635633278153,1.4523500544317842,1.2825150544453023,2.3009640601712826,0.3103813825441349,-0.40028941407932933,-0.11355235818258648,0.7787303765438011,0.13732362625944375,0.3817506123919569,1.1022436718162008,1.1937539044717103,-1.71722930421042,-0.6976711102245209,-0.7140728496646459,2.7223660452457783,0.474456483139522,1.1937539044717103,0.5644896226799964,2.664622633709218,-0.5535235918543128,-0.5535235918543128,-0.7972875946120856,-0.43037928832775996,0.474456483139522,1.0269530506694047,2.5892351771566373,0.15000139369493218,-0.15500001376748473,-1.4233578409590617,0.4284463495739996,1.6821282751850737,0.7579666967264426,-0.43037928832775996,-0.08621034266007742 | 2,948 |
Fetal distress | 10 | 25 | 3.011065 | 0.002603 | O96000,Q9NVI7,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q86Y39,Q9NPL8,O75306,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,322,37,135,8,44,77,240,339,95 | 8,839,339,1297,2796,129,95,1780,1825,1299,2531,1505,2765,1902,77,135,1789,44,1152,240,322,441,1137,596,37 | 3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-1.2850028396706408,1.9850015170325637,2.1700017598173678,-0.31162085873717893,-0.3409143906622731,-0.04562344444480704,-0.7972875946120856,-0.15500001376748473,-1.1705743485850078,-0.38534586462623527,2.343244888252367,1.9506190541438213,-0.31162085873717893,2.643303939387849,0.060186115633053816,1.4933010900118375,1.2737585000217826,0.9692152220740943,0.07317166718379643,0.662747577217144,2.7015163290761643 | 2,948 |
Translocase | 14 | 24 | 3.00404 | 0.002664 | Q8NBU5,Q13423,P20020,P05023,P23634,P35670,P08183,Q9HD20,O75306,Q04656,Q03519,P16615,P00403,P03886 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 489,170,485,301,493,494,332,83,339,469,281,122,60,95 | 839,339,1297,60,95,301,572,332,809,122,1825,485,493,2531,494,2312,858,2765,921,281,469,170,489,83 | 0.28622861567613295,1.2295800256388367,-0.04562344444480704,2.5059894136062666,2.1700017598173678,1.325909696379107,0.705432417367614,1.247331115968002,0.3223889389369212,2.0189623913532273,-0.3409143906622731,0.8704543213377697,0.8603984521649488,-0.7972875946120856,0.8603984521649488,-0.6328456266009942,0.27408278382771123,-1.1705743485850078,0.22502907537646621,1.3686697011472104,0.9103471386411612,1.808682116385517,0.8704543213377697,2.2641878529287944 | 2,948 |
Mitochondrial protein containing complex | 67 | 157 | 3.003451 | 0.002669 | Q9NS69,O96000,P14406,O43676,Q96IX5,Q99595,P00846,P21796,Q7Z7F7,Q8N4H5,Q5XKP0,P12236,Q53H12,Q9Y584,P13073,O14949,Q9Y6M9,P62072,P40939,Q8NE86,Q9Y5J9,Q96CU9,P05141,O60220,O60830,Q9UDW1,P12235,Q6UXV4,Q9NX14,Q9Y512,Q07812,P56385,P00403,Q9Y4W6,P21912,P06576,Q9NVH1,Q9BYC9,Q9Y5J7,O14548,Q86Y39,Q9Y375,Q9BUR5,P09622,O75306,Q3ZCQ8,Q9P0J0,Q9NX63,P82933,O94826,O75964,Q5HYI7,P20674,P03886,O75431,P56134,P24539,Q9BRJ2,P35232,O14925,P22695,Q99623,Q16891,Q7Z7H8,O00411,Q13505,Q9Y5L4 | Localization | GO Cellular component | msigdb_gocc | 2,129,7,8,520,10,14,15,272,19,279,154,539,28,155,33,37,294,426,427,298,44,303,302,49,50,433,313,441,318,570,312,60,577,188,572,321,580,196,448,77,596,81,337,339,470,86,599,604,89,88,215,601,95,223,615,231,357,486,108,109,238,370,246,507,123,254 | 782,507,1000,448,108,33,929,8,1322,302,721,49,839,339,774,223,1297,1774,88,1525,89,2095,2335,2542,129,685,60,14,95,303,572,1985,809,2837,337,1039,1872,686,1368,1752,433,154,155,7,633,932,810,1825,601,15,188,109,231,1439,2531,2532,1301,1441,486,900,2543,426,858,2459,1628,2765,2512,1850,803,1100,1393,1852,615,312,294,1534,812,1446,977,1612,604,570,123,2769,1084,1373,1223,370,470,539,215,279,825,313,1658,2771,272,246,77,2172,1885,19,1288,1311,427,1541,1575,44,2375,2034,1378,2036,520,2943,10,238,2501,1380,357,81,580,1168,1133,621,1356,767,2197,1293,1358,1230,683,2467,2,321,441,986,599,1069,1016,86,50,720,1139,1643,1092,596,1407,1720,734,577,318,28,196,298,254,1054,37 | 0.3581399659175588,0.8198384531051967,0.15000139369493218,0.9399248957090145,2.059171659276056,2.737894239182016,0.2126464378878266,3.0713505910312833,-0.05909615052808124,1.3172820683611308,0.451536002673528,2.605573158951584,0.28622861567613295,1.2295800256388367,0.36996742888124223,1.5655779034583233,-0.04562344444480704,-0.31162085873717893,2.233154239652949,-0.1689335436139936,2.2206406060146433,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,0.48585396547881715,2.5059894136062666,3.0256480119669416,2.1700017598173678,1.3172820683611308,0.705432417367614,-0.43037928832775996,0.3223889389369212,-1.4032600540214297,1.2384689484766933,0.12459546086867959,-0.37046919446512544,0.48585396547881715,-0.08621034266007742,-0.29707080001748704,0.9789156405018443,1.873447213431415,1.8663245911664819,3.1028556423025955,0.5755625753080114,0.2126464378878266,0.3223889389369212,-0.3409143906622731,0.6411810535042607,3.021031890458238,1.6897313558966025,2.059171659276056,1.525648527311823,-0.12730986022355953,-0.7972875946120856,-0.7972875946120856,-0.04562344444480704,-0.12730986022355953,0.8704543213377697,0.23736370252558897,-0.8141766528354556,0.998223014412092,0.27408278382771123,-0.7305540733601957,-0.22526782119676403,-1.1705743485850078,-0.780481520558001,-0.35565887677440616,0.33435101991744987,0.08610500976236193,-0.09985266152283995,-0.35565887677440616,0.6085459020758718,1.2825150544453023,1.3345119408817352,-0.1689335436139936,0.3223889389369212,-0.12730986022355953,0.17520713667950955,-0.2110933158886262,0.6411810535042607,0.7160115787906041,2.0189623913532273,-1.1705743485850078,0.09898651295405862,-0.08621034266007742,0.007714294292187978,1.1483517684971725,0.9103471386411612,0.7579666967264426,1.5892714807064798,1.3771469826873006,0.3103813825441349,1.2825150544453023,-0.23950372309971943,-1.1705743485850078,1.3940278465349503,1.4688001720482913,2.343244888252367,-0.5378809045039169,-0.37046919446512544,2.9507609398023713,-0.032206450409452865,-0.04562344444480704,0.998223014412092,-0.1689335436139936,-0.18292663566061074,2.643303939387849,-0.6651033942270582,-0.4455266972174347,-0.08621034266007742,-0.4455266972174347,0.7993537399833668,-5.63040417068764,3.0668174590396893,1.5014220561203693,-0.7637577132524961,-0.08621034266007742,1.1847290379125095,2.3009640601712826,0.6948166616430476,0.047147981735179874,0.07317166718379643,0.6085459020758718,-0.07262497853037561,0.393489808386937,-0.5535235918543128,-0.032206450409452865,-0.07262497853037561,0.007714294292187978,0.4972099678438886,-0.7305540733601957,3.2420278669660707,1.2737585000217826,0.9692152220740943,0.17520713667950955,0.6519831828829221,0.11181654260448975,0.15000139369493218,2.258009524162855,2.6001384504964156,0.4630172524838215,0.07317166718379643,-0.22526782119676403,0.09898651295405862,0.662747577217144,-0.09985266152283995,-0.26816160686466817,0.44001246034412966,0.705432417367614,1.2825150544453023,2.794047586014273,1.6515109252066653,1.3345119408817352,1.4523500544317842,0.12459546086867959,2.7015163290761643 | 2,948 |
Nuclear inner membrane | 7 | 19 | 3.002309 | 0.002679 | P50402,O94901,O75844,Q8IXM6,Q99720,Q14739,Q9H1E5 | Localization | GO Cellular component | msigdb_gocc | 195,198,43,112,21,118,23 | 43,198,687,1849,674,195,2265,603,777,1059,118,258,112,1013,21,2273,23,586,653 | 2.643303939387849,1.643804841337337,0.48585396547881715,-0.35565887677440616,0.4972099678438886,1.6591962119392685,-0.6008926353532796,0.6411810535042607,0.36996742888124223,0.11181654260448975,2.032430731714956,1.4358059044741707,2.0525107219769514,0.15000139369493218,2.936470354523948,-0.6008926353532796,2.897965745446129,0.6841640874618475,0.553377001040428 | 2,948 |
Glycerophospholipid biosynthesis | 15 | 25 | 2.981657 | 0.002867 | P48651,Q92604,Q9NPH0,P40939,Q8NF37,Q9NQZ5,Q96N66,Q9NUQ2,Q6UWP7,Q8NAN2,Q9UG56,Q8NCC3,Q53H12,Q8N2A8,Q8IV08 | Processes and pathways | Reactome Pathways | msigdb_reactome | 257,193,38,426,107,172,204,111,342,471,344,121,539,285,255 | 2256,1367,2530,426,916,257,1651,1852,1784,539,342,255,285,471,121,107,193,204,1891,2907,581,38,172,111,344 | -0.6008926353532796,-0.08621034266007742,-0.7972875946120856,0.998223014412092,0.22502907537646621,1.4358059044741707,-0.23950372309971943,-0.35565887677440616,-0.31162085873717893,0.7579666967264426,1.2206642044639127,1.444089792764959,1.3601676844230879,0.9103471386411612,2.025704776459826,2.065816515305065,1.666860800458015,1.6360778607291422,-0.37046919446512544,-1.9427309890832862,0.6948166616430476,2.6910284666880053,1.8013928596418074,2.059171659276056,1.2206642044639127 | 2,948 |
Mental deterioration | 47 | 94 | 2.972625 | 0.002953 | Q96RL7,Q9BQE5,P00846,P09651,Q5XKP0,P17900,Q8N5K1,O15118,Q9Y487,P21964,P54802,O95140,P43243,Q9NQZ5,P61916,Q8WVX9,O76024,P20700,O60220,O43681,O96008,Q14108,Q96F07,P00403,P21912,Q9NZJ7,O75503,O95470,Q03164,P16278,P07602,O43819,Q9UBB4,P50897,O75306,Q13510,O60313,P04062,P03886,P04350,P22626,P27544,Q10713,Q6PI48,P35670,Q9NPL8,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 383,4,14,657,279,145,665,151,292,161,167,546,674,172,688,561,424,687,302,555,685,54,703,60,188,189,191,64,65,199,324,582,590,78,339,84,219,93,95,351,611,229,233,620,494,240,379 | 807,151,694,555,582,302,219,1001,1524,339,191,424,546,64,685,60,14,95,93,2228,351,1038,324,2528,2358,2305,657,1872,768,199,2232,145,883,687,188,161,611,2383,229,1301,1041,379,494,1442,2312,1849,674,2683,78,2735,1756,167,784,2052,688,2079,2587,65,2315,2535,1010,233,2496,84,54,1476,2441,738,279,1909,620,1805,665,1573,561,1948,703,2423,383,2885,2501,4,1917,240,172,2928,1457,189,590,2279,2568,1362,1018,292 | 0.3223889389369212,1.8947068052131284,0.474456483139522,0.7370610056166005,0.6841640874618475,1.3172820683611308,1.5813953757113124,0.15000139369493218,-0.1689335436139936,1.2295800256388367,1.674504789012511,0.998223014412092,0.7475317096601524,2.4776479082465204,0.48585396547881715,2.5059894136062666,3.0256480119669416,2.1700017598173678,2.182750080789599,-0.5850288483198346,1.1937539044717103,0.12459546086867959,1.2649757514469988,-0.7972875946120856,-0.6651033942270582,-0.6328456266009942,0.5310317416999976,-0.37046919446512544,0.3817506123919569,1.643804841337337,-0.5850288483198346,1.9017575126557482,0.2496506471199293,0.48585396547881715,1.6897313558966025,1.8448473069506741,0.6194626505037427,-0.6813481805247098,1.5416869382636196,-0.04562344444480704,0.12459546086867959,1.1115226986611575,0.8603984521649488,-0.12730986022355953,-0.6328456266009942,-0.35565887677440616,0.4972099678438886,-0.9877958305297942,2.325205828646418,-1.077987350196644,-0.29707080001748704,1.8304371083321016,0.3581399659175588,-0.46074315377249025,0.48585396547881715,-0.4760292158199211,-0.8653490426838603,2.4719430888618175,-0.6328456266009942,-0.7972875946120856,0.15000139369493218,1.5175956622312197,-0.7637577132524961,2.258009524162855,2.572795002492806,-0.14112559981342382,-0.7140728496646459,0.4284463495739996,1.3771469826873006,-0.38534586462623527,0.6085459020758718,-0.3262352210800657,0.5197985937189371,-0.18292663566061074,0.7370610056166005,-0.40028941407932933,0.474456483139522,-0.6976711102245209,1.1022436718162008,-1.6307939198566663,-0.7637577132524961,3.190745333119537,-0.38534586462623527,1.4933010900118375,1.8013928596418074,-2.8601405847797996,-0.12730986022355953,1.6821282751850737,0.6734744686950634,-0.6008926353532796,-0.8311494216532105,-0.07262497853037561,0.15000139369493218,1.3516408047634436 | 2,948 |
Impaired vibratory sensation | 14 | 30 | 2.96529 | 0.003024 | Q96RL7,Q9H0B6,Q9Y619,O95140,O43819,O00400,O14773,Q6PI48,P00846,Q12768,Q8WVX9,Q9Y6X9,O75298,O00165 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 383,452,136,546,582,362,234,620,14,689,561,529,56,442 | 442,362,234,1722,928,582,56,942,546,14,1960,1279,687,2627,784,2052,1473,1266,1010,689,1514,1207,620,1030,561,383,452,136,1434,529 | 0.9594834119537029,1.1665962650895083,1.509520209213793,-0.2825845468972897,0.2126464378878266,0.6841640874618475,2.5617775528003315,0.2002154590345209,0.7475317096601524,3.0256480119669416,-0.4153003756640121,-0.032206450409452865,0.48585396547881715,-0.9172949987173196,0.3581399659175588,-0.46074315377249025,-0.14112559981342382,-0.018844762829244025,0.15000139369493218,0.48585396547881715,-0.15500001376748473,0.020912454144430923,0.6085459020758718,0.13732362625944375,0.7370610056166005,1.1022436718162008,0.9399248957090145,1.9506190541438213,-0.11355235818258648,0.7787303765438011 | 2,948 |
secondary carrier transporter | 11 | 14 | 2.957957 | 0.003097 | Q15043,Q02978,O75746,O00400,O95202,Q9BQT8,Q9H936,Q6NT16,Q8TB61,Q96ES6,Q9UBX3 | Functions | Panther Protein class | panther_protein_class | 382,420,456,362,138,268,622,206,79,309,57 | 362,456,138,1159,420,382,206,1309,79,309,268,622,57,652 | 1.1665962650895083,0.9300978254026866,1.9436911549131641,0.047147981735179874,1.007830322351225,1.1022436718162008,1.6205608074546058,-0.04562344444480704,2.325205828646418,1.2999501304431609,1.4108112793572933,0.6085459020758718,2.5617775528003315,0.553377001040428 | 2,948 |
Rough endoplasmic reticulum | 12 | 32 | 2.956384 | 0.003113 | Q9UGP8,P61619,P51571,Q5BJF2,P27824,Q9UQB8,Q5VV42,Q96A33,Q99442,Q8TCT9,Q9Y5M8,Q07065 | Localization | GO Cellular component | msigdb_gocc | 453,419,392,101,390,140,364,143,347,187,62,124 | 1553,457,1074,2159,2699,390,1203,1178,392,1344,804,1008,419,730,1879,2599,1266,1160,1564,124,1102,101,364,187,143,347,2447,2606,2200,453,140,62 | -0.18292663566061074,0.9300978254026866,0.09898651295405862,-0.5378809045039169,-1.0235920080980971,1.0835983952732648,0.020912454144430923,0.034056888274781295,1.0835983952732648,-0.07262497853037561,0.33435101991744987,0.15000139369493218,1.007830322351225,0.44001246034412966,-0.37046919446512544,-0.8825773941139174,-0.018844762829244025,0.047147981735179874,-0.18292663566061074,2.012203505380641,0.08610500976236193,2.111885928965945,1.1665962650895083,1.6973141274124246,1.9297833441110366,1.2117213408631573,-0.7140728496646459,-0.8825773941139174,-0.5535235918543128,0.9399248957090145,1.9436911549131641,2.500345305118897 | 2,948 |
Focal t2 hyperintense brainstem lesion | 9 | 18 | 2.952767 | 0.003149 | O96000,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q86Y39,Q9NPL8,O75306,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,37,135,8,44,77,240,339,95 | 8,839,339,1297,129,95,1825,2531,2765,77,135,1789,44,240,441,1137,596,37 | 3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,1.9850015170325637,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-1.1705743485850078,2.343244888252367,1.9506190541438213,-0.31162085873717893,2.643303939387849,1.4933010900118375,0.9692152220740943,0.07317166718379643,0.662747577217144,2.7015163290761643 | 2,948 |
Microbody membrane | 16 | 22 | 2.92349 | 0.003461 | P28288,P04035,Q6IAN0,P51648,Q8NBU5,Q9BY49,P40855,O75381,Q8WVX9,Q5T8D3,O43808,Q8TB36,Q15067,P51659,Q9UKU0,O00116 | Localization | GO Cellular component | msigdb_gocc | 515,100,393,71,489,169,395,398,561,434,405,666,531,722,158,632 | 632,405,1773,398,1003,100,2230,515,769,395,71,722,531,434,393,489,666,561,1637,2465,169,158 | 0.5755625753080114,1.0364688150319994,-0.31162085873717893,1.0554099937856247,0.15000139369493218,2.111885928965945,-0.5850288483198346,0.7993537399833668,0.3817506123919569,1.0648357439505178,2.384870448821206,0.451536002673528,0.7683661814306533,0.9789156405018443,1.0835983952732648,0.8704543213377697,0.5197985937189371,0.7370610056166005,-0.22526782119676403,-0.7305540733601957,1.8232041550571583,1.8520247203194133 | 2,948 |
Complex i biogenesis | 10 | 27 | 2.920745 | 0.003492 | O96000,Q9Y6M9,Q8IUX1,O43676,Q86Y39,Q9NPL8,Q7L592,O75306,Q9P0J0,P03886 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,37,135,8,77,240,403,339,86,95 | 8,839,339,1297,2095,2335,2542,129,95,1825,2531,2765,803,1373,1223,403,77,135,1789,650,1211,240,441,1137,86,596,37 | 3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-1.1705743485850078,0.33435101991744987,-0.08621034266007742,0.007714294292187978,1.0459544065506157,2.343244888252367,1.9506190541438213,-0.31162085873717893,0.553377001040428,0.020912454144430923,1.4933010900118375,0.9692152220740943,0.07317166718379643,2.258009524162855,0.662747577217144,2.7015163290761643 | 2,948 |
Respiratory electron transport chain | 23 | 51 | 2.919456 | 0.003506 | O96000,O75208,O43676,P13073,O14949,Q9Y6M9,Q7KZN9,Q9UDW1,Q9H3K2,P00403,P21912,O14548,O43819,O75746,Q9Y375,P09622,O75306,P04062,P20674,P03886,Q9H936,Q16134,P14927 | Processes and pathways | GO Biological process | msigdb_gobp | 129,381,8,155,33,37,174,50,179,60,188,448,582,456,596,337,339,93,601,95,622,508,633 | 1000,448,33,8,582,381,839,339,1297,456,2095,2335,2542,129,60,95,93,2430,1156,809,337,686,155,2433,2231,633,932,1825,601,188,2531,1301,1260,916,858,2765,803,2843,508,1373,1223,174,2885,1313,2039,179,622,50,652,596,37 | 0.15000139369493218,0.9399248957090145,2.737894239182016,3.0713505910312833,0.6841640874618475,1.1022436718162008,0.28622861567613295,1.2295800256388367,-0.04562344444480704,0.9300978254026866,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.5059894136062666,2.1700017598173678,2.182750080789599,-0.7140728496646459,0.047147981735179874,0.3223889389369212,1.2384689484766933,0.48585396547881715,1.8663245911664819,-0.7140728496646459,-0.5850288483198346,0.5755625753080114,0.2126464378878266,-0.3409143906622731,0.6411810535042607,1.6897313558966025,-0.7972875946120856,-0.04562344444480704,-0.018844762829244025,0.22502907537646621,0.27408278382771123,-1.1705743485850078,0.33435101991744987,-1.4233578409590617,0.8198384531051967,-0.08621034266007742,0.007714294292187978,1.772045557794017,-1.6307939198566663,-0.04562344444480704,-0.4455266972174347,1.7349266711727922,0.6085459020758718,2.6001384504964156,0.553377001040428,0.662747577217144,2.7015163290761643 | 2,948 |
Mitochondrial complex i assembly model oxphos system | 11 | 26 | 2.912921 | 0.003581 | O96000,Q9Y6M9,Q8IUX1,O43676,Q96CU9,Q9NPL8,Q7L592,O75306,Q9NX14,Q9P0J0,P03886 | Processes and pathways | WikiPathways | msigdb_wp | 129,37,135,8,44,240,403,339,441,86,95 | 8,339,1297,2095,2335,2542,129,95,1825,2531,2765,803,1373,403,135,1789,44,650,478,1211,240,441,1137,86,596,37 | 3.0713505910312833,1.2295800256388367,-0.04562344444480704,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-1.1705743485850078,0.33435101991744987,-0.08621034266007742,1.0459544065506157,1.9506190541438213,-0.31162085873717893,2.643303939387849,0.553377001040428,0.8904664767159661,0.020912454144430923,1.4933010900118375,0.9692152220740943,0.07317166718379643,2.258009524162855,0.662747577217144,2.7015163290761643 | 2,948 |
Horizontal nystagmus | 8 | 22 | 2.912034 | 0.003591 | P07602,Q9NW15,O14773,Q9H061,P00846,P04062,O60313,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 324,168,234,45,14,93,219,189 | 1897,807,234,928,219,942,359,14,93,324,687,1987,1100,784,902,2589,561,45,1108,168,189,2568 | -0.38534586462623527,0.3223889389369212,1.509520209213793,0.2126464378878266,1.5813953757113124,0.2002154590345209,1.1756765413677428,3.0256480119669416,2.182750080789599,1.2649757514469988,0.48585396547881715,-0.43037928832775996,0.08610500976236193,0.3581399659175588,0.23736370252558897,-0.8653490426838603,0.7370610056166005,2.6379469928697454,0.08610500976236193,1.8304371083321016,1.6821282751850737,-0.8311494216532105 | 2,948 |
Nucleotide transport | 9 | 10 | 2.910392 | 0.00361 | Q6NUK1,Q9HC21,O00400,P05141,Q8TB61,Q08722,O43808,P12236,Q9H2D1 | Processes and pathways | GO Biological process | msigdb_gobp | 320,225,362,303,79,117,405,154,31 | 362,405,303,433,154,117,320,79,31,225 | 1.1665962650895083,1.0364688150319994,1.3172820683611308,0.9789156405018443,1.873447213431415,2.0391403276957534,1.2737585000217826,2.325205828646418,2.7635696710490953,1.5655779034583233 | 2,948 |
Nucleobase containing compound transmembrane transporter activity | 9 | 11 | 2.909745 | 0.003617 | Q6NUK1,Q9HC21,O00400,L0R6Q1,P05141,Q8TB61,O43808,P12236,Q9H2D1 | Functions | GO Molecular function | msigdb_gomf | 320,225,362,299,303,79,405,154,31 | 299,362,405,303,433,154,602,320,79,31,225 | 1.325909696379107,1.1665962650895083,1.0364688150319994,1.3172820683611308,0.9789156405018443,1.873447213431415,0.6411810535042607,1.2737585000217826,2.325205828646418,2.7635696710490953,1.5655779034583233 | 2,948 |
Lipid transporter activity | 10 | 19 | 2.909032 | 0.003625 | Q4KMQ2,P28288,Q7Z3C6,Q9BZF1,Q14849,P08183,P17900,O15118,Q96AA3,Q96GC9 | Functions | GO Molecular function | msigdb_gomf | 352,515,518,581,104,332,145,151,186,221 | 151,332,145,1280,515,597,1651,688,1264,104,352,1309,518,186,221,1425,1813,581,2565 | 1.8947068052131284,1.247331115968002,1.9017575126557482,-0.032206450409452865,0.7993537399833668,0.6519831828829221,-0.23950372309971943,0.48585396547881715,-0.018844762829244025,2.105351748565537,1.1937539044717103,-0.04562344444480704,0.7993537399833668,1.7124191246748732,1.5813953757113124,-0.11355235818258648,-0.3262352210800657,0.6948166616430476,-0.8311494216532105 | 2,948 |
Respiratory distress | 21 | 51 | 2.901208 | 0.003717 | P51571,Q9Y619,P00846,P53007,P53701,Q9UHX1,O60762,Q9NX14,Q00325,Q9NZJ7,P10253,P07602,Q8TCJ2,O75306,Q13510,P04062,P04350,P03886,O95831,P23786,Q16134 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 392,136,14,530,289,166,545,441,440,189,325,324,335,339,84,93,351,95,359,232,508 | 582,2608,1462,545,339,2553,359,14,95,93,351,324,1202,325,2745,2433,634,1609,870,2699,1299,232,962,1260,1505,1783,392,803,530,1393,289,1734,1879,440,1331,2141,84,737,2588,508,335,2033,906,828,1135,441,189,166,2353,2281,136 | 0.6841640874618475,-0.8998924548835083,-0.14112559981342382,0.7475317096601524,1.2295800256388367,-0.8311494216532105,1.1756765413677428,3.0256480119669416,2.1700017598173678,2.182750080789599,1.1937539044717103,1.2649757514469988,0.020912454144430923,1.2649757514469988,-1.1147284406560949,-0.7140728496646459,0.5755625753080114,-0.2110933158886262,0.26189023374501835,-1.0235920080980971,-0.04562344444480704,1.5175956622312197,0.18773580450914448,-0.018844762829244025,-0.15500001376748473,-0.31162085873717893,1.0835983952732648,0.33435101991744987,0.7683661814306533,-0.09985266152283995,1.3516408047634436,-0.2825845468972897,-0.37046919446512544,0.9692152220740943,-0.05909615052808124,-0.5223107110430917,2.258009524162855,0.4284463495739996,-0.8653490426838603,0.8198384531051967,1.247331115968002,-0.4455266972174347,0.23736370252558897,0.3103813825441349,0.07317166718379643,0.9692152220740943,1.6821282751850737,1.8376514642013175,-0.6489360930417204,-0.6008926353532796,1.9506190541438213 | 2,948 |
Secondary alcohol metabolic process | 13 | 40 | 2.900659 | 0.003724 | Q15800,Q9BQE5,P04035,Q15392,P16435,Q14849,Q14534,O75845,Q14739,O15118,Q16850,P04062,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 34,4,100,134,200,104,75,137,118,151,185,93,94 | 151,1322,137,867,942,944,100,93,1556,1625,200,2612,2916,224,468,2583,946,636,1783,2512,2292,975,688,2314,2842,1448,2758,75,118,104,2835,134,1064,34,185,94,2836,4,343,1318 | 1.8947068052131284,-0.05909615052808124,1.9436911549131641,0.26189023374501835,0.2002154590345209,0.2002154590345209,2.111885928965945,2.182750080789599,-0.18292663566061074,-0.22526782119676403,1.643804841337337,-0.8998924548835083,-2.133625916476744,1.5655779034583233,0.9103471386411612,-0.8653490426838603,0.2002154590345209,0.5755625753080114,-0.31162085873717893,-0.780481520558001,-0.6168313523355917,0.17520713667950955,0.48585396547881715,-0.6328456266009942,-1.4233578409590617,-0.12730986022355953,-1.151859916150363,2.3611636015336126,2.032430731714956,2.105351748565537,-1.3832750243291831,1.957529717511198,0.11181654260448975,2.737894239182016,1.7124191246748732,2.176383375551823,-1.3832750243291831,3.190745333119537,1.2206642044639127,-0.04562344444480704 | 2,948 |
Protein transmembrane transporter activity | 9 | 12 | 2.899964 | 0.003732 | Q9NS69,Q9UGP8,P61619,Q99595,O14925,O60830,O94826,P49755,Q9Y584 | Functions | GO Molecular function | msigdb_gomf | 2,453,419,10,108,49,89,220,28 | 108,49,89,685,220,419,516,1084,10,2,453,28 | 2.059171659276056,2.605573158951584,2.2206406060146433,0.48585396547881715,1.5813953757113124,1.007830322351225,0.7993537399833668,0.09898651295405862,3.0668174590396893,3.2420278669660707,0.9399248957090145,2.794047586014273 | 2,948 |
Delusions | 6 | 19 | 2.897992 | 0.003756 | P21964,Q9BQE5,P07602,O60220,P04062,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 161,4,324,302,93,189 | 1071,555,302,93,324,2358,161,901,1302,1126,1968,1574,1164,383,4,1213,189,1191,652 | 0.09898651295405862,0.7370610056166005,1.3172820683611308,2.182750080789599,1.2649757514469988,-0.6651033942270582,1.8448473069506741,0.23736370252558897,-0.04562344444480704,0.07317166718379643,-0.4153003756640121,-0.18292663566061074,0.047147981735179874,1.1022436718162008,3.190745333119537,0.020912454144430923,1.6821282751850737,0.034056888274781295,0.553377001040428 | 2,948 |
Cristae formation | 11 | 22 | 2.896458 | 0.003774 | Q9NVH1,P24539,O75964,Q13505,P00846,Q9BUR5,Q5XKP0,Q6UXV4,Q9Y512,P56385,O75431 | Processes and pathways | Reactome Pathways | msigdb_reactome | 321,231,88,123,14,81,279,313,318,312,223 | 223,1774,88,14,572,810,231,1439,900,2543,2459,615,312,123,370,279,313,2894,81,321,599,318 | 1.5655779034583233,-0.31162085873717893,2.233154239652949,3.0256480119669416,0.705432417367614,0.3223889389369212,1.525648527311823,-0.12730986022355953,0.23736370252558897,-0.8141766528354556,-0.7305540733601957,0.6085459020758718,1.2825150544453023,2.0189623913532273,1.1483517684971725,1.3771469826873006,1.2825150544453023,-1.7612307722767848,2.3009640601712826,1.2737585000217826,0.6519831828829221,1.2825150544453023 | 2,948 |
Oxidoreductase complex | 11 | 55 | 2.890177 | 0.00385 | O43169,O96000,O14949,Q9Y6M9,O43676,Q96CU9,Q86Y39,P22695,Q9UDW1,Q9P0J0,P03886 | Localization | GO Cellular component | msigdb_gocc | 0,129,33,37,8,44,77,109,50,86,95 | 782,1000,33,0,8,1322,839,339,1297,2095,2335,2542,129,2719,944,95,2610,568,1985,809,337,1872,1368,1752,669,2433,633,1825,188,109,2625,2531,1301,1040,1441,2261,1260,916,858,2765,2512,803,2413,1373,1223,2027,77,44,441,86,2728,50,720,596,37 | 0.3581399659175588,0.15000139369493218,2.737894239182016,3.2420278669660707,3.0713505910312833,-0.05909615052808124,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,-1.0597609447700629,0.2002154590345209,2.1700017598173678,-0.8998924548835083,0.7160115787906041,-0.43037928832775996,0.3223889389369212,1.2384689484766933,-0.37046919446512544,-0.08621034266007742,-0.29707080001748704,0.5085247561108027,-0.7140728496646459,0.5755625753080114,-0.3409143906622731,1.6897313558966025,2.059171659276056,-0.9172949987173196,-0.7972875946120856,-0.04562344444480704,0.12459546086867959,-0.12730986022355953,-0.6008926353532796,-0.018844762829244025,0.22502907537646621,0.27408278382771123,-1.1705743485850078,-0.780481520558001,0.33435101991744987,-0.6976711102245209,-0.08621034266007742,0.007714294292187978,-0.4455266972174347,2.343244888252367,2.643303939387849,0.9692152220740943,2.258009524162855,-1.0597609447700629,2.6001384504964156,0.4630172524838215,0.662747577217144,2.7015163290761643 | 2,948 |
Proton transmembrane transport | 23 | 48 | 2.883571 | 0.003932 | P51790,P00846,P13073,Q13423,P05023,Q7KZN9,P05141,P12235,Q9UDW1,Q96ES6,Q00325,P56385,P00403,P06576,O14548,Q04656,Q8TAD4,O75964,P20674,P56134,P24539,O00400,Q99623 | Processes and pathways | GO Biological process | msigdb_gobp | 387,14,155,170,301,174,303,433,50,309,440,312,60,572,448,469,87,88,601,615,231,362,238 | 362,1000,448,1408,839,1774,88,60,14,301,303,572,809,686,433,155,810,601,1609,2792,231,1439,2532,1441,900,1442,2312,858,2459,387,615,312,1371,440,469,170,174,87,309,2885,238,2894,1694,622,50,2540,2450,1235 | 1.1665962650895083,0.15000139369493218,0.9399248957090145,-0.11355235818258648,0.28622861567613295,-0.31162085873717893,2.233154239652949,2.5059894136062666,3.0256480119669416,1.325909696379107,1.3172820683611308,0.705432417367614,0.3223889389369212,0.48585396547881715,0.9789156405018443,1.8663245911664819,0.3223889389369212,0.6411810535042607,-0.2110933158886262,-1.2656715296047802,1.525648527311823,-0.12730986022355953,-0.7972875946120856,-0.12730986022355953,0.23736370252558897,-0.12730986022355953,-0.6328456266009942,0.27408278382771123,-0.7305540733601957,1.0929356242486823,0.6085459020758718,1.2825150544453023,-0.08621034266007742,0.9692152220740943,0.9103471386411612,1.808682116385517,1.772045557794017,2.2518170558697803,1.2999501304431609,-1.6307939198566663,1.5014220561203693,-1.7612307722767848,-0.25380149284031334,0.6085459020758718,2.6001384504964156,-0.7972875946120856,-0.7140728496646459,0.007714294292187978 | 2,948 |
Nadh dehydrogenase complex | 6 | 22 | 2.883014 | 0.003939 | Q9Y6M9,O43676,Q96CU9,Q86Y39,Q9P0J0,P03886 | Localization | GO Cellular component | msigdb_gocc | 37,8,44,77,86,95 | 1000,8,839,339,1297,2095,2335,2542,129,95,1825,2531,2765,803,1373,1223,77,44,441,86,596,37 | 0.15000139369493218,3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-1.1705743485850078,0.33435101991744987,-0.08621034266007742,0.007714294292187978,2.343244888252367,2.643303939387849,0.9692152220740943,2.258009524162855,0.662747577217144,2.7015163290761643 | 2,948 |
Amino acid transmembrane transport | 13 | 15 | 2.872064 | 0.004078 | O60831,Q9UJS0,Q9Y619,O75746,P30825,O75915,Q9H936,Q9H9B4,Q96NB2,Q9H2H9,Q15758,P08195,Q96QD8 | Processes and pathways | GO Biological process | msigdb_gobp | 133,652,136,456,236,327,622,336,372,631,663,569,183 | 133,456,327,735,569,236,1102,663,372,183,631,622,336,652,136 | 1.957529717511198,0.9300978254026866,1.2561666700159204,0.4284463495739996,0.7160115787906041,1.509520209213793,0.08610500976236193,0.5197985937189371,1.1483517684971725,1.719941539725816,0.5865961083383107,0.6085459020758718,1.247331115968002,0.553377001040428,1.9506190541438213 | 2,948 |
Impaired proprioception | 17 | 37 | 2.869439 | 0.004112 | Q96RL7,Q9H0B6,P54802,Q9Y619,O95140,O43819,Q5THJ4,O00400,O14773,P00846,Q12768,Q8WVX9,Q9Y6X9,Q6PI48,O75298,O00165,Q8IV08 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 383,452,167,136,546,582,203,362,234,14,689,561,529,620,56,442,255 | 442,362,234,1722,928,582,56,942,546,14,2131,1960,1279,687,2046,2627,167,784,2052,1473,1266,1010,689,1060,1514,1207,203,620,255,1030,561,383,452,2568,136,1434,529 | 0.9594834119537029,1.1665962650895083,1.509520209213793,-0.2825845468972897,0.2126464378878266,0.6841640874618475,2.5617775528003315,0.2002154590345209,0.7475317096601524,3.0256480119669416,-0.5223107110430917,-0.4153003756640121,-0.032206450409452865,0.48585396547881715,-0.46074315377249025,-0.9172949987173196,1.8304371083321016,0.3581399659175588,-0.46074315377249025,-0.14112559981342382,-0.018844762829244025,0.15000139369493218,0.48585396547881715,0.11181654260448975,-0.15500001376748473,0.020912454144430923,1.6360778607291422,0.6085459020758718,1.444089792764959,0.13732362625944375,0.7370610056166005,1.1022436718162008,0.9399248957090145,-0.8311494216532105,1.9506190541438213,-0.11355235818258648,0.7787303765438011 | 2,948 |
Hepatic failure | 21 | 46 | 2.868546 | 0.004124 | P28288,Q9Y619,P40855,O75845,O75381,P00846,O15118,P40939,O43772,A2RRP1,P09622,Q13510,Q13043,P04062,P03886,P50416,P23786,Q10713,P35670,P01889,Q6PGP7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 515,136,395,137,398,14,151,426,567,323,337,84,598,93,95,97,232,233,494,614,126 | 323,151,773,567,1671,398,137,2111,14,614,95,93,1498,1649,809,337,2113,635,232,515,2878,494,2819,395,426,2410,97,1852,1903,233,598,84,1247,846,672,126,1227,1211,2425,2067,2328,1665,1717,1092,790,136 | 1.2649757514469988,1.8947068052131284,0.36996742888124223,0.7160115787906041,-0.25380149284031334,1.0554099937856247,1.9436911549131641,-0.5068124202196339,3.0256480119669416,0.6085459020758718,2.1700017598173678,2.182750080789599,-0.15500001376748473,-0.23950372309971943,0.3223889389369212,1.2384689484766933,-0.5068124202196339,0.5755625753080114,1.5175956622312197,0.7993537399833668,-1.5883383065270185,0.8603984521649488,-1.3436388023652246,1.0648357439505178,0.998223014412092,-0.6976711102245209,2.137867848356007,-0.35565887677440616,-0.38534586462623527,1.5175956622312197,0.6519831828829221,2.258009524162855,-0.005537980331740621,0.28622861567613295,0.5085247561108027,2.012203505380641,0.007714294292187978,0.020912454144430923,-0.6976711102245209,-0.46074315377249025,-0.6328456266009942,-0.23950372309971943,-0.26816160686466817,0.09898651295405862,0.3581399659175588,1.9506190541438213 | 2,948 |
ER-Golgi transport | 15 | 51 | 2.867811 | 0.004133 | Q9HCU5,Q96RQ1,O43731,Q9P2W9,P49069,P49257,P24390,P51572,Q5JRA6,Q12981,Q15363,Q9Y282,O95070,P49755,O95197 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 355,228,5,40,201,361,11,396,400,273,177,52,116,220,30 | 2012,854,783,2489,2201,5,1646,514,1870,116,30,1256,2749,2233,11,1781,1240,201,361,220,396,2787,2439,2363,1851,413,872,764,273,1804,177,1515,400,672,2617,1419,701,1863,1543,906,228,1379,355,542,40,2199,52,1521,1719,1387,1434 | -0.4455266972174347,0.27408278382771123,0.3581399659175588,-0.7637577132524961,-0.5692393713422798,3.16470177536829,-0.23950372309971943,0.7993537399833668,-0.37046919446512544,2.0391403276957534,2.7686743452412657,-0.018844762829244025,-1.133244923304272,-0.5850288483198346,3.044028574777508,-0.31162085873717893,-0.005537980331740621,1.643804841337337,1.1756765413677428,1.5813953757113124,1.0648357439505178,-1.2273237680303433,-0.7140728496646459,-0.6651033942270582,-0.35565887677440616,1.017406943541416,0.26189023374501835,0.393489808386937,1.3855996558557733,-0.3262352210800657,1.7349266711727922,-0.15500001376748473,1.0554099937856247,0.5085247561108027,-0.8998924548835083,-0.11355235818258648,0.474456483139522,-0.35565887677440616,-0.1689335436139936,0.23736370252558897,1.5496727044793,-0.08621034266007742,1.1937539044717103,0.7579666967264426,2.664622633709218,-0.5535235918543128,2.5892351771566373,-0.15500001376748473,-0.26816160686466817,-0.08621034266007742,-0.11355235818258648 | 2,948 |
Transporter | 83 | 180 | 2.858352 | 0.004258 | P28288,Q9BQE5,O43731,P24390,P00846,P53007,Q9Y584,Q9H2D1,Q9HC07,Q8N1F7,Q9P2W9,Q9UI14,Q8TEM1,Q12907,O60499,O43772,Q9UBX3,P08195,Q15070,Q70HW3,Q8TB61,Q8TAD4,P16615,Q9HD45,Q9Y619,O95202,Q93050,P17900,P12236,O43760,O43752,Q15363,Q96QD8,Q9NZJ7,Q9Y3B3,Q9Y6C9,Q6NT16,P49755,O15400,Q9HC21,P24539,P30825,Q00765,Q99805,Q9BQT8,Q03519,Q9Y487,Q8NFH4,P05023,P05141,Q96ES6,P56385,Q6NUK1,Q9H9B4,P08183,P49257,O00400,Q9H6H4,Q8IXU6,Q96NB2,O75027,Q9NV70,Q9NY64,Q15043,O14617,P51572,Q99523,O43808,P61619,Q02978,P12235,Q9Y3A6,Q00325,P11279,O75746,Q9H2V7,P53985,Q04656,P05026,P20020,P23634,P35670,Q13190 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 515,4,5,11,14,530,28,31,35,547,40,563,559,557,53,567,57,569,59,66,79,87,122,131,136,138,142,145,154,160,171,177,183,189,190,197,206,220,218,225,231,236,252,267,268,281,292,290,301,303,309,312,320,336,332,361,362,365,371,372,374,377,385,382,389,396,401,405,419,420,433,437,440,438,456,467,465,469,479,485,493,494,495 | 2813,1605,1897,362,2665,1750,2012,389,2886,218,5,171,160,567,405,53,865,2744,987,1646,374,866,456,1774,1870,138,623,1256,2749,685,14,301,479,303,572,332,569,1257,438,433,154,122,145,810,485,1609,2792,493,11,231,1439,515,1079,236,1781,494,900,1987,2312,1240,1651,361,220,396,659,793,2338,530,2787,2439,2313,465,2363,965,918,1851,1159,615,312,936,1371,419,872,1994,921,1264,440,2587,252,420,281,469,748,2140,689,886,557,495,2562,1763,1881,2024,382,59,2671,1103,177,1084,663,2888,206,320,1309,66,1268,605,371,547,290,87,2421,79,559,766,2618,1863,691,2877,1486,142,908,309,372,183,2423,2222,401,1167,267,4,268,2605,829,717,1052,799,31,631,467,365,622,336,35,225,131,733,377,385,189,1338,40,2199,1233,57,2450,563,2352,652,1215,789,1521,437,190,292,28,1770,790,136,1387,197 | 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| 2,948 |
Steroid metabolic process | 19 | 62 | 2.852075 | 0.004343 | Q9BQE5,Q15392,O75845,O15118,Q15800,P05023,Q16850,O95470,P16435,Q14534,Q13510,Q9UBM7,P04062,Q8WTV0,P35610,P04035,Q14849,Q14739,Q53GQ0 | Processes and pathways | GO Biological process | msigdb_gobp | 4,134,137,151,34,301,185,64,200,75,84,343,93,94,224,100,104,118,376 | 613,151,137,942,64,944,100,93,301,2909,1556,1625,2750,200,1280,1157,2612,2582,515,597,2916,224,468,2819,2583,946,1783,1756,722,2292,975,688,2314,2842,1448,1709,84,2758,75,118,104,2835,134,1478,1450,1064,34,185,376,847,406,94,1425,2501,4,1916,1034,2565,343,1318,1110,2568 | 0.6085459020758718,1.8947068052131284,1.9436911549131641,0.2002154590345209,2.4776479082465204,0.2002154590345209,2.111885928965945,2.182750080789599,1.325909696379107,-1.989541004416688,-0.18292663566061074,-0.22526782119676403,-1.133244923304272,1.643804841337337,-0.032206450409452865,0.047147981735179874,-0.8998924548835083,-0.8653490426838603,0.7993537399833668,0.6519831828829221,-2.133625916476744,1.5655779034583233,0.9103471386411612,-1.3436388023652246,-0.8653490426838603,0.2002154590345209,-0.31162085873717893,-0.29707080001748704,0.451536002673528,-0.6168313523355917,0.17520713667950955,0.48585396547881715,-0.6328456266009942,-1.4233578409590617,-0.12730986022355953,-0.26816160686466817,2.258009524162855,-1.151859916150363,2.3611636015336126,2.032430731714956,2.105351748565537,-1.3832750243291831,1.957529717511198,-0.14112559981342382,-0.12730986022355953,0.11181654260448975,2.737894239182016,1.7124191246748732,1.1207728642032955,0.28622861567613295,1.0364688150319994,2.176383375551823,-0.11355235818258648,-0.7637577132524961,3.190745333119537,-0.38534586462623527,0.13732362625944375,-0.8311494216532105,1.2206642044639127,-0.04562344444480704,0.08610500976236193,-0.8311494216532105 | 2,948 |
Mitochondrial calcium ion transport | 9 | 16 | 2.851735 | 0.004348 | P35232,Q8NE86,O95202,Q10713,P45880,Q99623,P21796,Q9H300,Q9Y277 | Processes and pathways | Reactome Pathways | msigdb_reactome | 486,427,138,233,13,238,15,152,159 | 2285,138,15,486,13,233,1885,427,1454,771,238,1380,152,1235,159,577 | -0.6168313523355917,1.9436911549131641,3.021031890458238,0.8704543213377697,3.03485502403842,1.5175956622312197,-0.37046919446512544,0.998223014412092,-0.12730986022355953,0.3817506123919569,1.5014220561203693,-0.08621034266007742,1.8947068052131284,0.007714294292187978,1.8520247203194133,0.705432417367614 | 2,948 |
Transition metal ion transport | 9 | 16 | 2.849602 | 0.004377 | Q15043,Q9HC07,O15173,Q8N4V1,Q9H9B4,Q9HD20,O75027,Q04656,Q8TAD4 | Processes and pathways | GO Biological process | msigdb_gobp | 382,35,36,102,336,83,374,469,87 | 36,374,1343,494,1390,921,2587,2054,469,382,102,87,2039,336,35,83 | 2.7171692744027514,1.1299943266097154,-0.07262497853037561,0.8603984521649488,-0.09985266152283995,0.22502907537646621,-0.8653490426838603,-0.46074315377249025,0.9103471386411612,1.1022436718162008,2.111885928965945,2.2518170558697803,-0.4455266972174347,1.247331115968002,2.7223660452457783,2.2641878529287944 | 2,948 |
Macromolecule transmembrane transporter activity | 9 | 13 | 2.827566 | 0.00469 | Q9NS69,Q9UGP8,P61619,Q99595,O14925,O60830,O94826,P49755,Q9Y584 | Functions | GO Molecular function | msigdb_gomf | 2,453,419,10,108,49,89,220,28 | 108,49,89,685,220,602,419,516,1084,10,2,453,28 | 2.059171659276056,2.605573158951584,2.2206406060146433,0.48585396547881715,1.5813953757113124,0.6411810535042607,1.007830322351225,0.7993537399833668,0.09898651295405862,3.0668174590396893,3.2420278669660707,0.9399248957090145,2.794047586014273 | 2,948 |
Cholesterol metabolism with bloch and kandutschrussell pathways | 11 | 24 | 2.8206 | 0.004793 | P35610,Q15800,P04035,Q15392,Q14534,O75845,O00767,Q14739,Q9UBM7,Q16850,O95864 | Processes and pathways | WikiPathways | msigdb_wp | 224,34,100,134,75,137,338,118,343,185,378 | 338,1773,137,1003,378,100,1625,769,224,468,946,1802,2842,1448,2758,75,118,2835,134,1064,34,185,909,343 | 1.2295800256388367,-0.31162085873717893,1.9436911549131641,0.15000139369493218,1.1115226986611575,2.111885928965945,-0.22526782119676403,0.3817506123919569,1.5655779034583233,0.9103471386411612,0.2002154590345209,-0.3262352210800657,-1.4233578409590617,-0.12730986022355953,-1.151859916150363,2.3611636015336126,2.032430731714956,-1.3832750243291831,1.957529717511198,0.11181654260448975,2.737894239182016,1.7124191246748732,0.23736370252558897,1.2206642044639127 | 2,948 |
Bulbar signs | 7 | 13 | 2.820216 | 0.004799 | P07602,P00846,P04062,Q99720,P35637,Q9NZJ7,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 324,14,93,21,379,189,95 | 555,14,95,93,1776,324,379,674,382,1543,21,189,1172 | 0.7370610056166005,3.0256480119669416,2.1700017598173678,2.182750080789599,-0.31162085873717893,1.2649757514469988,1.1115226986611575,0.4972099678438886,1.1022436718162008,-0.1689335436139936,2.936470354523948,1.6821282751850737,0.047147981735179874 | 2,948 |
Cation transmembrane transport | 57 | 126 | 2.81758 | 0.004839 | Q15043,P51790,Q6P4Q7,Q9Y619,O95202,P00846,P21796,P13073,Q9UM00,Q9HC07,P61619,Q9NW15,Q8NE86,Q13423,P05023,Q7KZN9,P05141,Q8IUH4,P12235,Q9UDW1,P46934,Q96ES6,O43772,Q00325,P08195,Q07812,P56385,P00403,Q9Y4W6,P27105,P06576,Q70HW3,O14548,P19174,Q9H9B4,Q9HD20,Q8TAD4,O75964,Q04656,Q96GC9,P20674,P05026,Q4KMQ2,Q9HC21,Q96AQ8,P56134,Q8N4V1,P24539,O00400,P30825,P20020,P23634,Q99623,P35670,Q96NB2,O75027,P16615 | Processes and pathways | GO Biological process | msigdb_gobp | 382,387,263,136,138,14,15,155,411,35,419,168,427,170,301,174,303,176,433,50,306,309,567,440,569,570,312,60,577,311,572,66,448,328,336,83,87,88,469,221,601,479,352,225,491,615,102,231,362,236,485,493,238,494,372,374,122 | 362,1000,448,1408,567,2666,374,839,2285,1774,88,138,1366,60,14,301,479,303,735,572,2132,1728,2357,569,809,1777,686,1556,433,155,122,810,328,485,601,1609,2792,2851,15,493,231,1439,311,2880,2734,2532,2077,236,1441,494,2890,900,1442,2312,306,1731,858,2459,1390,387,1560,918,1159,615,312,1371,419,1146,1330,675,921,440,2121,469,1709,1010,570,2243,1905,170,2725,2516,382,1103,663,352,263,66,174,176,1334,1885,102,427,87,1421,491,679,309,221,1423,372,850,2885,238,2894,1380,1694,2039,622,336,35,225,83,2606,1834,168,50,2540,2450,1235,411,940,2426,577,136 | 1.1665962650895083,0.15000139369493218,0.9399248957090145,-0.11355235818258648,0.7160115787906041,-0.9700354159181358,1.1299943266097154,0.28622861567613295,-0.6168313523355917,-0.31162085873717893,2.233154239652949,1.9436911549131641,-0.08621034266007742,2.5059894136062666,3.0256480119669416,1.325909696379107,0.8804769315934403,1.3172820683611308,0.4284463495739996,0.705432417367614,-0.5223107110430917,-0.2825845468972897,-0.6651033942270582,0.7160115787906041,0.3223889389369212,-0.31162085873717893,0.48585396547881715,-0.18292663566061074,0.9789156405018443,1.8663245911664819,2.0189623913532273,0.3223889389369212,1.2561666700159204,0.8704543213377697,0.6411810535042607,-0.2110933158886262,-1.2656715296047802,-1.4435695136020075,3.021031890458238,0.8603984521649488,1.525648527311823,-0.12730986022355953,1.2825150544453023,-1.6095037071757186,-1.077987350196644,-0.7972875946120856,-0.4760292158199211,1.509520209213793,-0.12730986022355953,0.8603984521649488,-1.71722930421042,0.23736370252558897,-0.12730986022355953,-0.6328456266009942,1.3086289242426126,-0.2825845468972897,0.27408278382771123,-0.7305540733601957,-0.09985266152283995,1.0929356242486823,-0.18292663566061074,0.22502907537646621,0.047147981735179874,0.6085459020758718,1.2825150544453023,-0.08621034266007742,1.007830322351225,0.060186115633053816,-0.05909615052808124,0.4972099678438886,0.22502907537646621,0.9692152220740943,-0.5068124202196339,0.9103471386411612,-0.26816160686466817,0.15000139369493218,0.7160115787906041,-0.5850288483198346,-0.38534586462623527,1.808682116385517,-1.0597609447700629,-0.780481520558001,1.1022436718162008,0.08610500976236193,0.5197985937189371,1.1937539044717103,1.4274982699452592,2.4719430888618175,1.772045557794017,1.757256508499432,-0.05909615052808124,-0.37046919446512544,2.111885928965945,0.998223014412092,2.2518170558697803,-0.11355235818258648,0.8704543213377697,0.4972099678438886,1.2999501304431609,1.5813953757113124,-0.11355235818258648,1.1483517684971725,0.28622861567613295,-1.6307939198566663,1.5014220561203693,-1.7612307722767848,-0.08621034266007742,-0.25380149284031334,-0.4455266972174347,0.6085459020758718,1.247331115968002,2.7223660452457783,1.5655779034583233,2.2641878529287944,-0.8825773941139174,-0.3409143906622731,1.8304371083321016,2.6001384504964156,-0.7972875946120856,-0.7140728496646459,0.007714294292187978,1.0269530506694047,0.2126464378878266,-0.6976711102245209,0.705432417367614,1.9506190541438213 | 2,948 |
Hormone metabolic process | 15 | 29 | 2.814211 | 0.00489 | O95470,Q6NUM9,Q8NBN7,Q9Y394,P16435,Q14849,O75844,P05023,Q9HB40,Q8NBQ5,Q8TAD4,Q53GQ0,O75787,P42892,Q9UBM7 | Processes and pathways | GO Biological process | msigdb_gobp | 64,259,227,429,200,104,43,301,80,406,87,376,443,156,343 | 2109,443,43,1552,64,301,480,2572,2750,200,597,156,2815,722,2854,104,1450,376,259,227,406,87,787,1423,2501,80,343,2568,429 | -0.5068124202196339,0.9594834119537029,2.643303939387849,-0.18292663566061074,2.4776479082465204,1.325909696379107,0.8804769315934403,-0.8482066366426134,-1.133244923304272,1.643804841337337,0.6519831828829221,1.8520247203194133,-1.323985431825699,0.451536002673528,-1.4435695136020075,2.105351748565537,-0.12730986022355953,1.1207728642032955,1.4358059044741707,1.5576363234614463,1.0364688150319994,2.2518170558697803,0.3581399659175588,-0.11355235818258648,-0.7637577132524961,2.3070449878206283,1.2206642044639127,-0.8311494216532105,0.998223014412092 | 2,948 |
Protein targeting | 43 | 117 | 2.81158 | 0.00493 | Q9NS69,P43307,Q15629,Q96RL7,Q99595,O14617,P40855,P51572,O75381,Q99523,Q8N4H5,P55786,O60725,Q9H300,Q15005,Q9Y584,O43615,P61619,P62072,Q9Y5J9,P57105,O60220,O60830,P46934,Q14108,Q9Y512,O00165,P27105,Q9Y5M8,Q9UGP8,Q9Y5J7,P46379,Q5THJ4,Q9P0J0,O94826,Q99442,O95831,Q10713,P49257,O14925,Q5JRX3,Q9Y5L4,Q9Y2T2 | Processes and pathways | GO Biological process | msigdb_gobp | 2,1,130,383,10,389,395,396,398,401,19,147,24,152,283,28,287,419,294,298,304,302,49,306,54,318,442,311,62,453,196,458,203,86,89,347,359,233,361,108,380,254,386 | 864,442,1196,1897,389,791,2908,108,684,694,287,555,2657,302,24,49,398,2285,2697,89,546,1497,1583,359,685,1527,1219,1960,1555,1901,2530,1528,311,1826,2880,597,2533,612,1677,556,2290,2212,395,1,458,306,361,1178,1559,833,396,147,304,1344,1827,1734,419,2079,294,1146,1902,1995,2241,2121,233,1905,1396,54,283,1102,1084,130,2294,1048,470,539,380,203,1452,1268,2673,2220,2104,19,666,1637,383,2464,347,401,1809,10,740,799,152,1293,2939,2,1715,86,2007,2278,453,1769,2540,781,1980,2398,386,742,838,318,28,196,298,254,62 | 0.26189023374501835,0.9594834119537029,0.020912454144430923,-0.38534586462623527,1.0835983952732648,0.34626792877763996,-1.9660618459113863,2.059171659276056,0.48585396547881715,0.474456483139522,1.3516408047634436,0.7370610056166005,-0.9523656803307052,1.3172820683611308,2.839099659223572,2.605573158951584,1.0554099937856247,-0.6168313523355917,-1.0235920080980971,2.2206406060146433,0.7475317096601524,-0.15500001376748473,-0.19697974106199748,1.1756765413677428,0.48585396547881715,-0.1689335436139936,0.007714294292187978,-0.4153003756640121,-0.18292663566061074,-0.38534586462623527,-0.7972875946120856,-0.1689335436139936,1.2825150544453023,-0.3409143906622731,-1.6095037071757186,0.6519831828829221,-0.7972875946120856,0.6194626505037427,-0.25380149284031334,0.7370610056166005,-0.6168313523355917,-0.5692393713422798,1.0648357439505178,3.2420278669660707,0.9300978254026866,1.3086289242426126,1.1756765413677428,0.034056888274781295,-0.18292663566061074,0.2983280445189644,1.0648357439505178,1.9017575126557482,1.3172820683611308,-0.07262497853037561,-0.3409143906622731,-0.2825845468972897,1.007830322351225,-0.4760292158199211,1.3345119408817352,0.060186115633053816,-0.38534586462623527,-0.43037928832775996,-0.5850288483198346,-0.5068124202196339,1.5175956622312197,-0.38534586462623527,-0.09985266152283995,2.572795002492806,1.3601676844230879,0.08610500976236193,0.09898651295405862,1.9850015170325637,-0.6168313523355917,0.12459546086867959,0.9103471386411612,0.7579666967264426,1.1115226986611575,1.6360778607291422,-0.12730986022355953,-0.018844762829244025,-0.9700354159181358,-0.5692393713422798,-0.4913854476709634,2.9507609398023713,0.5197985937189371,-0.22526782119676403,1.1022436718162008,-0.7305540733601957,1.2117213408631573,1.0554099937856247,-0.3262352210800657,3.0668174590396893,0.4284463495739996,0.34626792877763996,1.8947068052131284,-0.032206450409452865,-4.943199522395803,3.2420278669660707,-0.26816160686466817,2.258009524162855,-0.43037928832775996,-0.6008926353532796,0.9399248957090145,-0.29707080001748704,-0.7972875946120856,0.36996742888124223,-0.4153003756640121,-0.6813481805247098,1.1022436718162008,0.4284463495739996,0.2983280445189644,1.2825150544453023,2.794047586014273,1.6515109252066653,1.3345119408817352,1.4523500544317842,2.500345305118897 | 2,948 |
Atp synthesis coupled electron transport | 13 | 38 | 2.796879 | 0.00516 | O96000,O75208,O14949,Q9Y6M9,O43676,Q7KZN9,P09622,Q9UDW1,Q9H3K2,O75306,P13073,P00403,P03886 | Processes and pathways | GO Biological process | msigdb_gobp | 129,381,33,37,8,174,337,50,179,339,155,60,95 | 1000,448,33,8,381,839,339,1297,2095,2335,2542,129,60,95,1156,809,337,686,155,2231,633,932,1825,601,2531,1301,858,2765,803,1373,1223,174,2885,2039,179,50,596,37 | 0.15000139369493218,0.9399248957090145,2.737894239182016,3.0713505910312833,1.1022436718162008,0.28622861567613295,1.2295800256388367,-0.04562344444480704,-0.4913854476709634,-0.6489360930417204,-0.8141766528354556,1.9850015170325637,2.5059894136062666,2.1700017598173678,0.047147981735179874,0.3223889389369212,1.2384689484766933,0.48585396547881715,1.8663245911664819,-0.5850288483198346,0.5755625753080114,0.2126464378878266,-0.3409143906622731,0.6411810535042607,-0.7972875946120856,-0.04562344444480704,0.27408278382771123,-1.1705743485850078,0.33435101991744987,-0.08621034266007742,0.007714294292187978,1.772045557794017,-1.6307939198566663,-0.4455266972174347,1.7349266711727922,2.6001384504964156,0.662747577217144,2.7015163290761643 | 2,948 |
Amino acid transport | 13 | 21 | 2.794527 | 0.005198 | O60831,Q9UJS0,Q9H2H9,Q9Y619,O75746,O75915,P30825,Q9H936,Q9H9B4,Q96NB2,Q96QD8,P08195,Q6P4A7 | Processes and pathways | GO Biological process | msigdb_gobp | 133,652,631,136,456,327,236,622,336,372,183,569,91 | 2908,133,456,327,735,569,989,236,1159,1102,1062,663,91,1376,372,183,631,622,336,652,136 | -1.9660618459113863,1.957529717511198,0.9300978254026866,1.2561666700159204,0.4284463495739996,0.7160115787906041,0.16262911454544973,1.509520209213793,0.047147981735179874,0.08610500976236193,0.11181654260448975,0.5197985937189371,2.1954390050858774,-0.08621034266007742,1.1483517684971725,1.719941539725816,0.5865961083383107,0.6085459020758718,1.247331115968002,0.553377001040428,1.9506190541438213 | 2,948 |
Poor eye contact | 13 | 38 | 2.785821 | 0.005339 | O96000,Q9Y6M9,Q9UHX1,Q8IUX1,O43676,Q96CU9,Q86Y39,Q9NPL8,Q5XKP0,O75306,Q9NX14,Q9P0J0,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,37,166,135,8,44,77,240,279,339,441,86,95 | 8,839,339,1297,456,129,95,1825,2531,2407,2765,1756,530,2629,1536,1010,824,1267,1999,889,279,77,135,1789,2823,44,2061,1227,1152,1917,240,2620,441,1137,86,166,596,37 | 3.0713505910312833,0.28622861567613295,1.2295800256388367,-0.04562344444480704,0.9300978254026866,1.9850015170325637,2.1700017598173678,-0.3409143906622731,-0.7972875946120856,-0.6976711102245209,-1.1705743485850078,-0.29707080001748704,0.7683661814306533,-0.9172949987173196,-0.1689335436139936,0.15000139369493218,0.3103813825441349,-0.018844762829244025,-0.43037928832775996,0.2496506471199293,1.3771469826873006,2.343244888252367,1.9506190541438213,-0.31162085873717893,-1.3436388023652246,2.643303939387849,-0.46074315377249025,0.007714294292187978,0.060186115633053816,-0.38534586462623527,1.4933010900118375,-0.8998924548835083,0.9692152220740943,0.07317166718379643,2.258009524162855,1.8376514642013175,0.662747577217144,2.7015163290761643 | 2,948 |
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