term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial membrane organization
27
49
3.402198
0.000668
Q9Y512,Q9NS69,O95202,P45880,Q9H3K2,P0DP25,Q9Y5L4,Q3ZCQ8,O14737,Q5XKP0,Q9BUR5,P52789,Q6UXV4,Q9P0J0,Q53H12,O60313,Q8WWC4,P12235,Q16891,Q8IWA4,Q15070,Q13505,Q8IXI1,Q9NX63,P17152,P05141,Q9UII2
Processes and pathways
GO Biological process
msigdb_gobp
650,2,139,12,401,656,541,537,652,287,421,293,299,303,442,308,323,457,341,738,94,353,486,383,504,627,649
2695,652,308,749,1633,1284,139,1535,627,876,2044,656,457,504,3182,1504,3015,2099,3016,12,2207,2587,2174,293,879,353,1686,94,341,537,442,287,299,738,486,1077,3031,323,421,401,2,1211,383,303,649,1938,812,650,541
-0.6388487645543015,0.6724902109286491,1.3403798125660904,0.5615113239535318,-0.10586048643661662,0.09961191055323138,2.0077854950437413,-0.048735570818035576,0.7035921494358485,0.4137558381966468,-0.3025146589063486,0.6724902109286491,1.0149975096355603,0.8995196748229518,-1.005414393292386,-0.02987854200342981,-0.8410331326310951,-0.3227289322669874,-0.8410331326310951,3.5880722275384778,-0.3839946459113293,-0.5736141057694272,-0.3634680295925095,1.4045013303564935,0.4137558381966468,1.2352459870262076,-0.12508928118991622,2.396734762422103,1.261829326445677,0.8403559612194028,1.0432918958486117,1.442407617676143,1.3917722506837715,0.5775714858809151,0.9432620224784491,0.24244901301698119,-0.8410331326310951,1.3143936999272097,1.085314604290465,1.1405784257109197,4.030663110153479,0.15380286431879417,1.181463958349545,1.3789958573127592,0.6880742208527362,-0.24248241020736983,0.4965652697383779,0.6880742208527362,0.8403559612194028
3,477
Golgi cisterna
19
27
3.386637
0.000708
Q96L58,Q8WVM8,Q8N6G5,Q10713,Q8NBN3,O00461,Q10472,P98194,Q9P2E5,P51572,Q15363,P04439,Q9Y6B6,Q9H4A6,Q8NBZ7,O95249,Q8WVQ1,Q99523,Q8TBA6
Localization
GO Cellular component
msigdb_gocc
256,781,137,416,295,172,305,186,716,585,81,468,747,350,487,240,241,496,254
172,240,468,2199,585,186,1193,818,1758,305,416,2056,81,2762,137,295,487,254,781,241,256,496,350,716,1935,1527,747
1.7771424058672443,1.5899540873792353,0.972129499196718,-0.3839946459113293,0.7650123908871262,1.731319631584345,0.15380286431879417,0.4801497856111335,-0.16383228267364128,1.3661718533156093,1.0992119552130728,-0.3025146589063486,2.470913514380328,-0.6608278481110601,2.018372441939004,1.4045013303564935,0.9432620224784491,1.541480881266963,0.5291804175825732,1.5899540873792353,1.5292533775321773,0.9287404597149378,1.2485630214820864,0.6094837793071348,-0.24248241020736983,-0.02987854200342981,0.5775714858809151
3,477
Membrane lipid biosynthetic process
13
27
3.377751
0.000731
Q96G23,Q5H8A4,O15121,Q13510,O95470,P04062,Q8NBX0,P27544,Q16739,Q9P035,Q53H12,Q99805,Q06136
Processes and pathways
GO Biological process
msigdb_gobp
324,512,133,100,105,106,269,124,83,437,442,223,219
133,542,1018,654,1220,105,106,2505,2047,124,1960,219,100,83,442,512,2640,269,782,1551,324,1379,223,839,1987,437,1492
2.0394430613633685,0.8254121420894225,0.27733733002235417,0.6724902109286491,0.13582414108741372,2.3014619358985096,2.291773758375661,-0.5306993975719276,-0.3025146589063486,2.0915258852348777,-0.262392262257652,1.649582259474987,2.358972488129669,2.461737501871504,1.0432918958486117,0.8848196367866663,-0.595242946157797,1.4923045082617816,0.5291804175825732,-0.048735570818035576,1.3143936999272097,0.04464637679634543,1.649582259474987,0.4636616464692855,-0.262392262257652,1.0573549420901271,-0.011112566654353354
3,477
Electron transport chain oxphos system in mitochondria
26
53
3.373906
0.000741
O75306,P14406,O96000,P31930,P00403,O43676,P00846,P56385,P13073,O75964,P12236,P14927,O75880,Q9UDW1,O43920,P12235,O95168,P24539,O95169,O14548,O14949,Q9Y6M9,P20674,P05141,P21912,Q9UII2
Processes and pathways
WikiPathways
msigdb_wp
128,5,510,643,258,19,20,283,159,32,418,301,304,50,561,457,582,339,82,351,109,116,628,627,125,649
920,351,109,1000,19,3365,561,1995,128,1498,1355,304,1283,32,582,82,3416,890,510,258,20,903,3418,627,655,1316,457,418,159,5,1874,301,2091,1828,628,125,731,339,1569,3393,2667,643,942,2173,3249,861,845,283,2933,1341,50,649,116
0.363176231493417,1.2352459870262076,2.252720884481982,0.29466182574769184,3.3399034479628043,-1.3808477342331456,0.795338037054623,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,0.04464637679634543,1.3661718533156093,0.09961191055323138,3.141943931656318,0.7650123908871262,2.461737501871504,-1.6506750213514003,0.3969715892812894,0.8848196367866663,1.5169816611056757,3.333065755789585,0.3801119112602281,-1.6785966185631933,0.7035921494358485,0.6724902109286491,0.08137704720652839,1.0149975096355603,1.085314604290465,1.866928176818198,3.8385255731536114,-0.2226723202632471,1.3789958573127592,-0.3227289322669874,-0.2029611534569842,0.7035921494358485,2.0811764381859885,0.5775714858809151,1.261829326445677,-0.06768439960582033,-1.4867799433989366,-0.6169874837196055,0.6880742208527362,0.34616397120861425,-0.3634680295925095,-1.1023275684761824,0.4304652245976121,0.4471003091088909,1.4549503603205254,-0.7725283500753476,0.0630554350483885,2.825233750109732,0.6880742208527362,2.16305244697371
3,477
Dementia
23
61
3.367546
0.000758
O76024,P05067,P00403,Q14108,O15118,Q9NZJ7,P00846,P17900,P07602,P61916,O60313,P35670,P22626,Q9NQZ5,Q13510,P04062,P06865,Q8IY17,Q96RL7,P35637,Q9Y487,P27544,P21912
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
387,134,258,14,142,406,20,408,24,420,308,326,460,354,100,106,235,367,495,369,123,124,125
902,142,592,758,308,1786,387,527,258,20,903,3418,106,2621,134,235,24,977,1679,1875,408,1089,125,460,2988,124,2667,369,326,843,2048,3212,981,1537,1393,2862,420,2930,1192,1760,794,100,14,1293,1608,2399,367,1129,1344,2220,1078,2688,495,3423,3362,2221,354,406,636,1937,123
0.3801119112602281,1.9865073756421463,0.7497541290280656,0.5453811397505782,1.3403798125660904,-0.18334808070797615,1.1678883030223781,0.8552381999638872,1.5169816611056757,3.333065755789585,0.3801119112602281,-1.6785966185631933,2.291773758375661,-0.595242946157797,2.0394430613633685,1.613932265149701,3.2426404073511974,0.31190736282418247,-0.12508928118991622,-0.2226723202632471,1.1130548036372934,0.22488395017924478,2.0811764381859885,1.000765413691891,-0.8180718103176833,2.0915258852348777,-0.6169874837196055,1.1949872162647377,1.3013270958737004,0.4471003091088909,-0.3025146589063486,-1.053592111071168,0.31190736282418247,-0.048735570818035576,0.02614916726068394,-0.7274827145107601,1.085314604290465,-0.7725283500753476,0.15380286431879417,-0.16383228267364128,0.5129086364034002,2.358972488129669,3.4206854913567066,0.09961191055323138,-0.08672578350961495,-0.4671696555646836,1.2084584164574235,0.2072374453876056,0.0630554350483885,-0.3839946459113293,0.24244901301698119,-0.6169874837196055,0.9287404597149378,-1.6785966185631933,-1.3547654978043482,-0.3839946459113293,1.2352459870262076,1.1268435085723476,0.7035921494358485,-0.24248241020736983,2.101842136086416
3,477
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
31
67
3.367403
0.000759
O75306,O96000,P31930,P00403,O43676,P00846,P06576,P56385,P13073,Q9Y375,O75964,Q9NX14,P14927,Q9P0J0,O75880,Q9UDW1,O43920,Q16134,O43819,Q86Y39,Q8N183,O95168,P24539,O95169,Q9BQ95,O14548,O14949,Q9NPL8,Q9Y6M9,P20674,P21912
Processes and pathways
Reactome Pathways
msigdb_reactome
128,510,643,258,19,20,655,283,159,289,32,552,301,303,304,50,561,696,573,193,587,582,339,82,743,351,109,371,116,628,125
920,351,109,1000,19,3365,573,561,1995,128,1498,1355,304,1283,32,582,82,3416,890,510,258,20,903,3418,655,830,1316,159,2896,1874,301,2091,1828,628,125,731,339,1569,3393,2667,643,942,2098,2003,2173,3249,861,845,283,1257,696,2933,1341,193,587,3031,894,743,2999,1382,371,552,1108,303,50,289,116
0.363176231493417,1.2352459870262076,2.252720884481982,0.29466182574769184,3.3399034479628043,-1.3808477342331456,0.7802068776839349,0.795338037054623,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,0.04464637679634543,1.3661718533156093,0.09961191055323138,3.141943931656318,0.7650123908871262,2.461737501871504,-1.6506750213514003,0.3969715892812894,0.8848196367866663,1.5169816611056757,3.333065755789585,0.3801119112602281,-1.6785966185631933,0.6724902109286491,0.4636616464692855,0.08137704720652839,1.866928176818198,-0.7499438782500567,-0.2226723202632471,1.3789958573127592,-0.3227289322669874,-0.2029611534569842,0.7035921494358485,2.0811764381859885,0.5775714858809151,1.261829326445677,-0.06768439960582033,-1.4867799433989366,-0.6169874837196055,0.6880742208527362,0.34616397120861425,-0.3227289322669874,-0.2824027254226025,-0.3634680295925095,-1.1023275684761824,0.4304652245976121,0.4471003091088909,1.4549503603205254,0.11776071457762759,0.6253369160329553,-0.7725283500753476,0.0630554350483885,1.7081694282043638,0.7650123908871262,-0.8410331326310951,0.3969715892812894,0.5775714858809151,-0.8180718103176833,0.04464637679634543,1.1949872162647377,0.8254121420894225,0.22488395017924478,1.3789958573127592,2.825233750109732,1.442407617676143,2.16305244697371
3,477
Intracellular protein transmembrane transport
13
21
3.361999
0.000774
O60830,Q99595,O95831,O75298,Q99442,Q15629,O43615,O14925,O96008,Q15388,O75381,P31751,Q3ZCQ8
Processes and pathways
GO Biological process
msigdb_gobp
0,1,227,597,588,69,454,173,527,463,362,426,537
173,454,0,597,362,1633,227,527,2200,426,1917,1955,1170,463,69,537,1076,588,1,917,637
1.7771424058672443,1.0149975096355603,4.258503091616609,0.7344316400083396,1.2084584164574235,-0.10586048643661662,1.6377408954325872,0.8552381999638872,-0.3839946459113293,1.071362388503744,-0.24248241020736983,-0.262392262257652,0.17169755104451068,0.9864762058893607,2.5877825531853427,0.8403559612194028,0.24244901301698119,0.7650123908871262,4.258503091616609,0.3801119112602281,0.7035921494358485
3,477
Lipid localization
28
81
3.348454
0.000813
Q4KMQ2,P50416,Q14108,O15118,Q99720,Q9H6V9,Q9NZJ7,P17900,P07602,P35790,Q5T3U5,Q7Z3C6,P61916,Q9BUR5,Q14534,P30536,Q9BQE5,Q8WTV0,Q9UID3,Q16739,P08183,Q9BZF3,O43772,P23786,Q9H2V7,P04062,Q9Y3D6,O15260
Processes and pathways
GO Biological process
msigdb_gobp
389,394,14,142,16,18,406,408,24,410,155,161,420,421,175,309,62,71,209,83,211,85,215,93,97,106,372,374
935,3476,142,374,803,215,1282,1630,1063,2089,1222,938,1870,106,1825,1567,24,1287,2950,211,1067,2468,408,2047,1333,93,1048,1503,309,1117,426,1436,1049,2507,410,3413,394,420,3219,3451,1960,3341,14,175,3254,83,389,155,1096,1582,161,751,1202,2764,71,662,1268,1658,1157,16,62,2361,421,2490,1040,85,3298,97,558,1775,18,1246,406,1492,1621,209,956,2844,372,852,747
0.34616397120861425,-11.437289207600141,1.9865073756421463,1.181463958349545,0.4965652697383779,1.649582259474987,0.09961191055323138,-0.10586048643661662,0.24244901301698119,-0.3227289322669874,0.13582414108741372,0.34616397120861425,-0.2226723202632471,2.291773758375661,-0.2029611534569842,-0.06768439960582033,3.2426404073511974,0.09961191055323138,-0.7952372743225334,1.6613819875037117,0.24244901301698119,-0.5094115023895259,1.1130548036372934,-0.3025146589063486,0.0630554350483885,2.396734762422103,0.25993326491209245,-0.02987854200342981,1.3403798125660904,0.2072374453876056,1.071362388503744,0.007563093228499072,0.25993326491209245,-0.5306993975719276,1.1130548036372934,-1.622929555485722,1.1542599074685331,1.085314604290465,-1.053592111071168,-2.11991428298489,-0.262392262257652,-1.3030706558113276,3.4206854913567066,1.7771424058672443,-1.1023275684761824,2.461737501871504,1.1678883030223781,1.8999766035038268,0.22488395017924478,-0.06768439960582033,1.8558377322438417,0.5615113239535318,0.15380286431879417,-0.6608278481110601,2.5700894098740656,0.6724902109286491,0.11776071457762759,-0.10586048643661662,0.18950886067998413,3.387308237114521,2.6833023859483847,-0.4462137510231218,1.085314604290465,-0.5094115023895259,0.27733733002235417,2.4433035969920236,-1.176500576169906,2.3779106499781055,0.8104063122296249,-0.16383228267364128,3.367089603944026,0.13582414108741372,1.1268435085723476,-0.011112566654353354,-0.08672578350961495,1.6731403254770958,0.34616397120861425,-0.7051437292628466,1.1949872162647377,0.4471003091088909,0.5775714858809151
3,477
Abnormal circulating cholesterol concentration
13
34
3.344137
0.000825
P61916,Q15125,P38571,Q9NVI7,Q15800,Q15904,Q8N511,Q9NZJ7,P37268,P07602,O75845,Q14739,Q15392
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
420,167,232,368,141,270,79,406,117,24,375,187,126
749,375,1251,1748,24,1191,117,232,3212,2508,789,2823,1069,420,2340,1758,2012,2711,187,167,126,883,141,270,1009,79,1516,991,2406,368,406,1988,465,747
0.5615113239535318,1.181463958349545,0.11776071457762759,-0.16383228267364128,3.2426404073511974,0.15380286431879417,2.142778735840569,1.6258576473578923,-1.053592111071168,-0.5306993975719276,0.5129086364034002,-0.7051437292628466,0.24244901301698119,1.085314604290465,-0.4462137510231218,-0.16383228267364128,-0.2824027254226025,-0.6388487645543015,1.731319631584345,1.8110987672570336,2.0811764381859885,0.4137558381966468,2.0077854950437413,1.4798985250540877,0.29466182574769184,2.4982794163821613,-0.02987854200342981,0.31190736282418247,-0.4671696555646836,1.2084584164574235,1.1268435085723476,-0.262392262257652,0.9864762058893607,0.5775714858809151
3,477
Transition metal ion homeostasis
12
27
3.307237
0.000942
O75027,P02794,Q15043,P05067,P30519,P09601,Q15904,O75880,Q8N511,Q8NEW0,Q9Y487,Q9Y5Y0
Processes and pathways
GO Biological process
msigdb_gobp
129,192,164,134,8,41,270,304,79,114,123,189
2695,3273,573,2237,129,2464,304,3368,1163,192,2583,134,41,2819,8,2622,326,2048,1438,1839,2342,164,270,79,114,123,189
-0.6388487645543015,-1.1516317262366567,0.7802068776839349,-0.4046271871534076,2.0603772329418755,-0.5094115023895259,1.3661718533156093,-1.3808477342331456,0.17169755104451068,1.7081694282043638,-0.5736141057694272,2.0394430613633685,2.9762603054079118,-0.7051437292628466,3.780969419215487,-0.595242946157797,1.3013270958737004,-0.3025146589063486,0.007563093228499072,-0.2029611534569842,-0.4462137510231218,1.8335441178353415,1.4798985250540877,2.4982794163821613,2.16305244697371,2.101842136086416,1.731319631584345
3,477
Golgi cisterna membrane
16
22
3.306954
0.000943
Q96L58,Q8NBZ7,Q8NBN3,Q8WVM8,Q8N6G5,P51572,O00461,Q99523,Q10472,Q9P2E5,Q15363,Q8WVQ1,Q9Y6B6,P98194,Q9H4A6,Q10713
Localization
GO Cellular component
msigdb_gocc
256,487,295,781,137,585,172,496,305,716,81,241,747,186,350,416
172,2199,585,186,1193,818,1758,305,416,81,137,295,487,781,241,256,496,350,716,1935,1527,747
1.7771424058672443,-0.3839946459113293,0.7650123908871262,1.731319631584345,0.15380286431879417,0.4801497856111335,-0.16383228267364128,1.3661718533156093,1.0992119552130728,2.470913514380328,2.018372441939004,1.4045013303564935,0.9432620224784491,0.5291804175825732,1.5899540873792353,1.5292533775321773,0.9287404597149378,1.2485630214820864,0.6094837793071348,-0.24248241020736983,-0.02987854200342981,0.5775714858809151
3,477
primary active transporter
16
26
3.304005
0.000953
Q9NS69,P05023,Q8N4H5,Q6P4A7,P35670,Q9H2J7,Q6NTF9,Q9GZP9,P16615,O96008,Q15388,O75381,Q9BUN8,Q96NB2,P98194,P20020
Functions
Panther Protein class
panther_protein_class
2,291,34,67,326,229,328,329,231,527,463,362,595,380,186,447
874,362,1633,527,291,3330,2135,231,447,877,326,1023,186,463,863,328,67,34,1202,380,595,329,229,667,917,2
0.4137558381966468,1.2084584164574235,-0.10586048643661662,0.8552381999638872,1.4171833906612892,-1.2774548997014639,-0.3430464255779581,1.6258576473578923,1.029172877098212,0.4137558381966468,1.3013270958737004,0.27733733002235417,1.731319631584345,0.9864762058893607,0.4304652245976121,1.3013270958737004,2.6402555038244877,3.127266464039714,0.15380286431879417,1.181463958349545,0.7497541290280656,1.3013270958737004,1.6377408954325872,0.6724902109286491,0.3801119112602281,4.030663110153479
3,477
Respirasome
17
47
3.28812
0.001009
O75306,Q9Y375,Q86Y39,Q13423,P14406,P00403,P14927,Q96CU9,Q9P0J0,O14949,Q9UDW1,O43676,O95169,Q9Y6M9,Q6DKK2,P21912,P13073
Localization
GO Cellular component
msigdb_gocc
128,289,193,36,5,258,301,77,303,109,50,19,82,116,152,125,159
920,351,109,1000,19,3365,561,1995,128,1498,1355,582,82,3416,890,510,258,903,3418,830,1316,159,5,1874,301,2091,1828,628,125,731,3393,2667,643,3249,861,36,2933,1341,152,193,77,552,303,50,1938,289,116
0.363176231493417,1.2352459870262076,2.252720884481982,0.29466182574769184,3.3399034479628043,-1.3808477342331456,0.795338037054623,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,0.04464637679634543,0.7650123908871262,2.461737501871504,-1.6506750213514003,0.3969715892812894,0.8848196367866663,1.5169816611056757,0.3801119112602281,-1.6785966185631933,0.4636616464692855,0.08137704720652839,1.866928176818198,3.8385255731536114,-0.2226723202632471,1.3789958573127592,-0.3227289322669874,-0.2029611534569842,0.7035921494358485,2.0811764381859885,0.5775714858809151,-1.4867799433989366,-0.6169874837196055,0.6880742208527362,-1.1023275684761824,0.4304652245976121,3.0902434831082837,-0.7725283500753476,0.0630554350483885,1.9326950418116124,1.7081694282043638,2.525404913107488,0.8254121420894225,1.3789958573127592,2.825233750109732,-0.24248241020736983,1.442407617676143,2.16305244697371
3,477
Metal ion homeostasis
28
88
3.273424
0.001063
O75027,O76024,P05067,P30519,Q8IYU8,O95202,Q9Y5X3,Q15904,Q96A33,P05023,Q15043,P09601,P78417,O75880,P98194,Q9Y5Y0,Q8WWC4,P02794,P35670,Q8N511,Q16891,Q9HD20,Q9Y639,P16615,Q8NEW0,Q9BPX6,Q9Y3D6,Q9Y487
Processes and pathways
GO Biological process
msigdb_gobp
129,387,134,8,136,139,272,270,157,291,164,41,174,304,186,189,323,192,326,79,341,101,361,231,114,244,372,123
2695,3273,1992,573,3085,2237,129,2464,304,3368,387,139,1532,1163,192,2583,1223,291,134,1536,1287,961,3275,1500,41,656,2853,1165,231,3191,1681,447,2819,877,3377,2953,2138,8,2622,326,2048,3212,585,1572,1023,790,1438,1004,3263,174,1839,186,2594,879,2516,2342,3390,395,777,164,2056,270,341,2720,3202,1928,136,79,513,547,114,323,157,2562,1976,676,244,916,101,995,956,701,372,123,812,272,189,361
-0.6388487645543015,-1.1516317262366567,-0.2824027254226025,0.7802068776839349,-0.9106897973314252,-0.4046271871534076,2.0603772329418755,-0.5094115023895259,1.3661718533156093,-1.3808477342331456,1.1678883030223781,2.0077854950437413,-0.048735570818035576,0.17169755104451068,1.7081694282043638,-0.5736141057694272,0.13582414108741372,1.4171833906612892,2.0394430613633685,-0.048735570818035576,0.09961191055323138,0.3290745454164685,-1.1516317262366567,-0.02987854200342981,2.9762603054079118,0.6724902109286491,-0.7274827145107601,0.17169755104451068,1.6258576473578923,-1.0294342081393086,-0.12508928118991622,1.029172877098212,-0.7051437292628466,0.4137558381966468,-1.4070886524662474,-0.7952372743225334,-0.3430464255779581,3.780969419215487,-0.595242946157797,1.3013270958737004,-0.3025146589063486,-1.053592111071168,0.7650123908871262,-0.06768439960582033,0.27733733002235417,0.5129086364034002,0.007563093228499072,0.29466182574769184,-1.1269078629663312,1.7771424058672443,-0.2029611534569842,1.731319631584345,-0.5736141057694272,0.4137558381966468,-0.5306993975719276,-0.4462137510231218,-1.4600530886095953,1.1542599074685331,0.5291804175825732,1.8335441178353415,-0.3025146589063486,1.4798985250540877,1.261829326445677,-0.6388487645543015,-1.0294342081393086,-0.24248241020736983,2.0289249011183346,2.4982794163821613,0.8848196367866663,0.8254121420894225,2.16305244697371,1.3143936999272097,1.8889974025961502,-0.5520999295887415,-0.262392262257652,0.6568396443727869,1.577900780996791,0.3801119112602281,2.358972488129669,0.31190736282418247,0.34616397120861425,0.6253369160329553,1.1949872162647377,2.101842136086416,0.4965652697383779,1.4798985250540877,1.731319631584345,1.2218778955284642
3,477
membrane trafficking regulatory protein
9
22
3.267821
0.001084
P11279,Q8WTV0,Q9P253,O43760,Q14108,P24390,O43731,O00560,Q96EA4
Functions
Panther Protein class
panther_protein_class
482,71,517,107,14,15,58,534,478
1247,1427,534,58,107,1532,482,15,984,14,2016,2056,71,1153,781,1324,478,2121,610,1857,1492,517
0.11776071457762759,0.007563093228499072,0.8403559612194028,2.72574613566304,2.2820557203662677,-0.048735570818035576,0.9432620224784491,3.394015562843155,0.31190736282418247,3.4206854913567066,-0.2824027254226025,-0.3025146589063486,2.5700894098740656,0.18950886067998413,0.5291804175825732,0.08137704720652839,0.9577249028843212,-0.3227289322669874,0.7344316400083396,-0.2029611534569842,-0.011112566654353354,0.8848196367866663
3,477
Endoplasmic reticulum organization
19
43
3.238697
0.001201
O43681,Q8NFQ8,P46379,Q5JRA6,Q15041,Q96A33,O95197,Q12981,Q8N4V1,P49257,Q15629,Q15363,Q8N5M9,Q9H6H4,P57088,Q9NQC3,Q00765,Q8NHH9,Q9P2W9
Processes and pathways
GO Biological process
msigdb_gobp
758,780,393,796,536,157,39,428,56,694,69,81,337,611,602,102,483,243,127
935,902,1017,1868,1673,758,1189,2948,39,1532,393,694,602,966,1170,483,793,428,911,536,81,69,1728,796,2304,56,337,1099,780,243,157,2361,1618,2260,2073,1461,611,1303,102,1987,2572,1492,127
0.34616397120861425,0.3801119112602281,0.27733733002235417,-0.2226723202632471,-0.12508928118991622,0.5453811397505782,0.15380286431879417,-0.7952372743225334,3.0223888856624046,-0.048735570818035576,1.1542599074685331,0.6253369160329553,0.7344316400083396,0.3290745454164685,0.17169755104451068,0.9432620224784491,0.5129086364034002,1.071362388503744,0.3801119112602281,0.8403559612194028,2.470913514380328,2.5877825531853427,-0.14441294960249149,0.5129086364034002,-0.42536657713018505,2.7676008494517013,1.2750452265193046,0.22488395017924478,0.5291804175825732,1.577900780996791,1.8889974025961502,-0.4462137510231218,-0.08672578350961495,-0.4046271871534076,-0.3025146589063486,0.007563093228499072,0.7344316400083396,0.09961191055323138,2.358972488129669,-0.262392262257652,-0.5520999295887415,-0.011112566654353354,2.0811764381859885
3,477
Steroid binding
13
24
3.224652
0.001261
P38435,P05023,P61916,O15173,P04062,Q9H4L5,P45880,O15118,Q14108,O00264,Q9BZF3,P21796,P30536
Functions
GO Molecular function
msigdb_gomf
162,291,420,104,106,558,12,142,14,273,85,23,309
273,142,104,875,1142,106,563,291,3275,23,2047,1333,309,2507,162,12,420,14,3254,1157,2490,1040,85,558
1.4674472355220745,1.9865073756421463,2.311120407130275,0.4137558381966468,0.18950886067998413,2.291773758375661,0.795338037054623,1.4171833906612892,-1.1516317262366567,3.284733395150704,-0.3025146589063486,0.0630554350483885,1.3403798125660904,-0.5306993975719276,1.8447097839425666,3.5880722275384778,1.085314604290465,3.4206854913567066,-1.1023275684761824,0.18950886067998413,-0.5094115023895259,0.27733733002235417,2.4433035969920236,0.8104063122296249
3,477
Inner mitochondrial membrane organization
16
20
3.212841
0.001314
Q8WWC4,Q13505,Q9Y512,Q9BUR5,P17152,O95202,Q6UXV4,Q9P0J0,Q9H3K2,O75431,Q16891,Q53H12,O60313,Q9Y5L4,Q9NX63,Q5XKP0
Processes and pathways
GO Biological process
msigdb_gobp
323,353,650,421,504,139,299,303,401,749,341,442,308,541,383,287
308,749,1633,139,504,2099,353,341,442,287,299,323,421,401,1211,383,303,812,650,541
1.3403798125660904,0.5615113239535318,-0.10586048643661662,2.0077854950437413,0.8995196748229518,-0.3227289322669874,1.2352459870262076,1.261829326445677,1.0432918958486117,1.442407617676143,1.3917722506837715,1.3143936999272097,1.085314604290465,1.1405784257109197,0.15380286431879417,1.181463958349545,1.3789958573127592,0.4965652697383779,0.6880742208527362,0.8403559612194028
3,477
Primary mitochondrial disease
35
98
3.202674
0.001362
Q9BW92,O75306,P00403,Q9BQT8,Q9Y2R0,O43676,P00846,Q96IX5,Q6DKK2,Q5XKP0,P13073,Q9Y375,Q9NX14,Q9NWS8,P14927,Q9P0J0,O75880,Q9UBX3,O60313,Q53H12,O43819,Q6P4A7,Q86Y39,P12235,Q8N183,Q96CU9,O95169,O95831,Q86YH6,O14949,Q9NPL8,Q9Y6M9,Q9NYY8,P20674,Q70HW3
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
648,128,258,522,13,19,20,533,152,287,159,289,552,434,301,303,304,54,308,442,573,67,193,457,587,77,82,227,615,109,371,116,635,628,122
920,109,19,3365,573,308,1995,128,1498,1355,1088,304,82,890,227,258,20,903,3418,2380,830,1116,457,159,1874,301,1828,628,731,1569,3393,2667,3434,2003,2546,1915,3249,2549,1120,2902,1575,2553,1007,1400,1341,442,1234,1608,645,1483,287,152,67,122,1486,193,615,587,2307,686,894,2561,77,1738,533,1378,3423,742,2403,522,1521,2999,755,648,1273,1382,2609,371,434,552,635,1108,303,2652,54,2316,1938,2270,13,1309,1386,889,289,1990,998,1216,1940,116
0.363176231493417,2.252720884481982,3.3399034479628043,-1.3808477342331456,0.7802068776839349,1.3403798125660904,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,0.04464637679634543,0.22488395017924478,1.3661718533156093,2.461737501871504,0.3969715892812894,1.6377408954325872,1.5169816611056757,3.333065755789585,0.3801119112602281,-1.6785966185631933,-0.4671696555646836,0.4636616464692855,0.2072374453876056,1.0149975096355603,1.866928176818198,-0.2226723202632471,1.3789958573127592,-0.2029611534569842,0.7035921494358485,0.5775714858809151,-0.06768439960582033,-1.4867799433989366,-0.6169874837196055,-1.7920825787050783,-0.2824027254226025,-0.5520999295887415,-0.24248241020736983,-1.1023275684761824,-0.5520999295887415,0.2072374453876056,-0.7499438782500567,-0.06768439960582033,-0.5520999295887415,0.29466182574769184,0.02614916726068394,0.0630554350483885,1.0432918958486117,0.13582414108741372,-0.08672578350961495,0.6880742208527362,-0.011112566654353354,1.442407617676143,1.9326950418116124,2.6402555038244877,2.101842136086416,-0.011112566654353354,1.7081694282043638,0.719044467209736,0.7650123908871262,-0.42536657713018505,0.6411220410730749,0.3969715892812894,-0.5520999295887415,2.525404913107488,-0.14441294960249149,0.8552381999638872,0.04464637679634543,-1.6785966185631933,0.5775714858809151,-0.4671696555646836,0.870059284479323,-0.02987854200342981,-0.8180718103176833,0.5615113239535318,0.6880742208527362,0.11776071457762759,0.04464637679634543,-0.5736141057694272,1.1949872162647377,1.071362388503744,0.8254121420894225,0.7035921494358485,0.22488395017924478,1.3789958573127592,-0.595242946157797,2.784180874695723,-0.42536657713018505,-0.24248241020736983,-0.4046271871534076,3.518485936002134,0.09961191055323138,0.04464637679634543,0.4137558381966468,1.442407617676143,-0.262392262257652,0.31190736282418247,0.15380286431879417,-0.24248241020736983,2.16305244697371
3,477
Cellular ion homeostasis
31
97
3.199607
0.001376
O75027,O75787,O76024,P05067,Q8IYU8,O95202,Q15904,Q93050,P50897,Q96A33,P05023,Q15043,P09601,P78417,O75503,O75880,P98194,Q9Y5Y0,Q8WWC4,P02794,P35670,Q8N511,Q16891,Q9HD20,Q9Y639,P16615,P51790,Q8NEW0,Q9BPX6,Q9Y3D6,Q9Y487
Processes and pathways
GO Biological process
msigdb_gobp
129,386,387,134,136,139,270,17,26,157,291,164,41,174,47,304,186,189,323,192,326,79,341,101,361,231,108,114,244,372,123
2695,3273,1942,573,3085,2237,129,2464,47,386,304,3368,387,139,1532,1163,192,3092,291,134,1536,655,1287,961,3275,1500,41,2199,656,3118,2853,1165,231,3191,1681,447,2819,877,2542,3377,2953,2138,2386,2622,326,2048,3212,26,2247,585,108,1572,1023,790,1438,1004,3263,174,186,2594,2708,879,3390,395,777,2804,164,2056,270,341,3202,1928,136,79,547,114,323,507,17,157,1324,2562,1976,676,244,101,995,2410,1279,956,701,372,123,812,189,361,3347
-0.6388487645543015,-1.1516317262366567,-0.262392262257652,0.7802068776839349,-0.9106897973314252,-0.4046271871534076,2.0603772329418755,-0.5094115023895259,2.8495972795541524,1.1678883030223781,1.3661718533156093,-1.3808477342331456,1.1678883030223781,2.0077854950437413,-0.048735570818035576,0.17169755104451068,1.7081694282043638,-0.9106897973314252,1.4171833906612892,2.0394430613633685,-0.048735570818035576,0.6724902109286491,0.09961191055323138,0.3290745454164685,-1.1516317262366567,-0.02987854200342981,2.9762603054079118,-0.3839946459113293,0.6724902109286491,-0.9341703246969754,-0.7274827145107601,0.17169755104451068,1.6258576473578923,-1.0294342081393086,-0.12508928118991622,1.029172877098212,-0.7051437292628466,0.4137558381966468,-0.5520999295887415,-1.4070886524662474,-0.7952372743225334,-0.3430464255779581,-0.4671696555646836,-0.595242946157797,1.3013270958737004,-0.3025146589063486,-1.053592111071168,3.2355640449184544,-0.4046271871534076,0.7650123908871262,2.2625294404559577,-0.06768439960582033,0.27733733002235417,0.5129086364034002,0.007563093228499072,0.29466182574769184,-1.1269078629663312,1.7771424058672443,1.731319631584345,-0.5736141057694272,-0.6388487645543015,0.4137558381966468,-1.4600530886095953,1.1542599074685331,0.5291804175825732,-0.6829258074091615,1.8335441178353415,-0.3025146589063486,1.4798985250540877,1.261829326445677,-1.0294342081393086,-0.24248241020736983,2.0289249011183346,2.4982794163821613,0.8254121420894225,2.16305244697371,1.3143936999272097,0.8995196748229518,3.373845322764859,1.8889974025961502,0.08137704720652839,-0.5520999295887415,-0.262392262257652,0.6568396443727869,1.577900780996791,2.358972488129669,0.31190736282418247,-0.4671696555646836,0.11776071457762759,0.34616397120861425,0.6253369160329553,1.1949872162647377,2.101842136086416,0.4965652697383779,1.731319631584345,1.2218778955284642,-1.3030706558113276
3,477
Inorganic anion transport
11
30
3.193976
0.001403
Q15043,Q9UHG3,P45880,P51790,P08183,Q9UBX3,P21796,Q9Y277,Q5T3U5,P30536,Q9C0H2
Processes and pathways
GO Biological process
msigdb_gobp
164,38,12,108,211,54,23,250,155,309,31
2979,803,758,3092,211,2199,23,309,1049,12,108,586,1146,790,1050,943,164,389,155,1261,2358,607,916,31,974,54,38,250,957,3347
-0.8180718103176833,0.4965652697383779,0.5453811397505782,-0.9106897973314252,1.6613819875037117,-0.3839946459113293,3.284733395150704,1.3403798125660904,0.25993326491209245,3.5880722275384778,2.2625294404559577,0.7650123908871262,0.18950886067998413,0.5129086364034002,0.25993326491209245,0.34616397120861425,1.8335441178353415,1.1678883030223781,1.8999766035038268,0.11776071457762759,-0.4462137510231218,0.7344316400083396,0.3801119112602281,3.1783138805528677,0.3290745454164685,2.784180874695723,3.030006778420197,1.5536644399111408,0.34616397120861425,-1.3030706558113276
3,477
Organic acid transmembrane transporter activity
17
23
3.18389
0.001453
P08195,P41440,Q9H2J7,P53985,Q96NB2,Q9BQT8,O15439,Q9H9B4,Q9Y289,Q9H2D1,Q9UJS0,O75746,P30825,P08183,Q9UBX3,Q9Y619,Q15758
Functions
GO Molecular function
msigdb_gomf
922,388,229,489,380,522,803,667,957,143,465,593,307,211,54,247,863
1942,803,593,1431,211,922,307,1049,388,1599,489,943,863,1582,380,522,143,229,667,54,465,957,247
-0.262392262257652,0.4965652697383779,0.7497541290280656,0.007563093228499072,1.6613819875037117,0.363176231493417,1.3532999391374014,0.25993326491209245,1.1678883030223781,-0.08672578350961495,0.9287404597149378,0.34616397120861425,0.4304652245976121,-0.06768439960582033,1.181463958349545,0.870059284479323,1.9865073756421463,1.6377408954325872,0.6724902109286491,2.784180874695723,0.9864762058893607,0.34616397120861425,1.5658043187937936
3,477
Organelle inner membrane
115
258
3.158978
0.001583
O60830,Q99595,O96000,P14406,Q9BQT8,Q9Y2R0,O96008,Q99720,O43676,Q96IX5,P00846,Q9Y5L4,Q9UDX5,Q3ZCQ8,Q69YU5,Q8NE86,O75964,Q9NX14,Q13423,P40939,Q9UDW1,Q9Y2U8,Q9UBX3,O43920,O43819,Q9H1E5,Q6P4A7,Q8N183,Q9H061,Q96CU9,O95168,O75746,O95169,O75844,Q15070,P62995,P35232,P23786,Q9H2V7,Q9NX20,O14949,Q7Z7H8,Q9Y6M9,Q9NRK6,Q70HW3,P20674,P05141,O75600,P21912,O75306,O75027,Q9Y512,P43304,P31930,Q8IYU8,O95202,Q9H2D1,Q6DKK2,P13073,O14925,Q14739,Q9Y5Y0,Q86Y39,Q8NBN7,Q567V2,P53701,O43772,O95831,Q9UH99,Q9BPX6,Q9Y6C9,Q9Y619,Q9H9P8,P00403,P82933,O76062,P56385,Q5XKP0,Q99623,Q9Y375,Q9BSK2,Q6UXV4,Q9UG56,P14927,Q16540,Q9P0J0,O75880,O60313,Q9NQ50,Q8WWC4,P24539,Q16891,Q9H2W6,O14548,Q13505,Q9NVI7,Q9NPL8,Q9NX63,Q96NB2,Q9H3K2,Q9HC21,Q10713,P12236,Q9BUR5,Q8IXM6,Q6NUK1,Q53H12,P22830,P12235,O43615,Q9UJS0,Q8IXM3,Q5SNT2,Q14728,P17152
Localization
GO Cellular component
msigdb_gocc
0,1,510,5,522,13,527,16,19,533,20,541,25,537,28,547,32,552,36,553,50,570,54,561,573,65,67,587,74,77,582,593,82,89,94,603,600,93,97,619,109,111,116,634,122,628,627,626,125,128,129,650,644,643,136,139,143,152,159,173,187,189,193,203,206,204,215,227,230,244,248,247,255,258,276,274,283,287,288,289,297,299,300,301,302,303,304,308,318,323,339,341,344,351,353,368,371,383,380,401,414,416,418,421,432,429,442,458,457,454,465,477,484,491,504
920,351,173,109,454,1000,19,3365,215,573,561,308,0,129,1995,128,1498,1944,749,1996,1355,626,1066,593,89,304,1283,32,2088,274,814,582,82,3416,139,890,1431,938,227,510,527,258,20,903,3418,1677,627,655,2241,961,830,1116,2044,1316,2200,457,418,1908,159,5,1874,301,2091,504,2539,773,1828,628,1089,125,2664,731,458,1715,93,339,1569,3393,2667,643,1020,600,942,924,2099,3434,553,2003,981,644,2173,3414,3419,3249,2474,789,2336,861,1120,1599,204,1393,2753,845,283,3252,603,1575,718,1171,1508,2142,732,1796,2553,276,1050,943,2104,416,1257,1258,1196,1291,36,353,1844,491,187,94,696,302,2933,1341,341,537,442,206,1607,484,2398,287,28,152,429,1802,67,797,299,1447,122,2520,111,193,477,432,136,587,1297,1098,3031,2441,203,2938,2443,547,686,1450,323,1010,1655,1416,897,77,2156,1658,2644,915,1269,533,380,1038,1,288,16,244,743,522,744,1521,297,991,2999,755,421,1060,1555,932,1810,1245,1184,74,65,143,97,344,401,1382,667,2609,255,917,414,2690,1276,371,318,634,1897,1211,368,994,1859,552,619,383,1278,1107,1108,303,54,50,25,300,230,465,956,1938,1623,2270,13,1308,1309,570,889,289,1990,1783,998,1216,812,650,541,189,247,1866,248,116
0.363176231493417,1.2352459870262076,1.7771424058672443,2.252720884481982,1.0149975096355603,0.29466182574769184,3.3399034479628043,-1.3808477342331456,1.649582259474987,0.7802068776839349,0.795338037054623,1.3403798125660904,4.258503091616609,2.0603772329418755,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,-0.262392262257652,0.5615113239535318,-0.2824027254226025,0.04464637679634543,0.7035921494358485,0.24244901301698119,0.7497541290280656,2.415445977405476,1.3661718533156093,0.09961191055323138,3.141943931656318,-0.3227289322669874,1.4674472355220745,0.4801497856111335,0.7650123908871262,2.461737501871504,-1.6506750213514003,2.0077854950437413,0.3969715892812894,0.007563093228499072,0.34616397120861425,1.6377408954325872,0.8848196367866663,0.8552381999638872,1.5169816611056757,3.333065755789585,0.3801119112602281,-1.6785966185631933,-0.12508928118991622,0.7035921494358485,0.6724902109286491,-0.4046271871534076,0.3290745454164685,0.4636616464692855,0.2072374453876056,-0.3025146589063486,0.08137704720652839,-0.3839946459113293,1.0149975096355603,1.085314604290465,-0.24248241020736983,1.866928176818198,3.8385255731536114,-0.2226723202632471,1.3789958573127592,-0.3227289322669874,0.8995196748229518,-0.5520999295887415,0.5291804175825732,-0.2029611534569842,0.7035921494358485,0.22488395017924478,2.0811764381859885,-0.6169874837196055,0.5775714858809151,1.0149975096355603,-0.14441294960249149,2.396734762422103,1.261829326445677,-0.06768439960582033,-1.4867799433989366,-0.6169874837196055,0.6880742208527362,0.27733733002235417,0.7344316400083396,0.34616397120861425,0.363176231493417,-0.3227289322669874,-1.7920825787050783,0.8104063122296249,-0.2824027254226025,0.31190736282418247,0.6880742208527362,-0.3634680295925095,-1.622929555485722,-1.6785966185631933,-1.1023275684761824,-0.5094115023895259,0.5129086364034002,-0.4462137510231218,0.4304652245976121,0.2072374453876056,-0.08672578350961495,1.6731403254770958,0.02614916726068394,-0.6608278481110601,0.4471003091088909,1.4549503603205254,-1.1023275684761824,0.7344316400083396,-0.06768439960582033,0.5935621359363286,0.17169755104451068,-0.02987854200342981,-0.3430464255779581,0.5775714858809151,-0.18334808070797615,-0.5520999295887415,1.4674472355220745,0.25993326491209245,0.34616397120861425,-0.3227289322669874,1.0992119552130728,0.11776071457762759,0.11776071457762759,0.15380286431879417,0.09961191055323138,3.0902434831082837,1.2352459870262076,-0.2029611534569842,0.9287404597149378,1.731319631584345,2.396734762422103,0.6253369160329553,1.3789958573127592,-0.7725283500753476,0.0630554350483885,1.261829326445677,0.8403559612194028,1.0432918958486117,1.6731403254770958,-0.08672578350961495,0.9432620224784491,-0.4671696555646836,1.442407617676143,3.207082017569042,1.9326950418116124,1.071362388503744,-0.18334808070797615,2.6402555038244877,0.5129086364034002,1.3917722506837715,0.007563093228499072,2.101842136086416,-0.5306993975719276,2.2131801686928103,1.7081694282043638,0.9577249028843212,1.071362388503744,2.0289249011183346,0.7650123908871262,0.09961191055323138,0.22488395017924478,-0.8410331326310951,-0.48823524922289674,1.6848575173151885,-0.7725283500753476,-0.48823524922289674,0.8254121420894225,0.6411220410730749,0.007563093228499072,1.3143936999272097,0.29466182574769184,-0.10586048643661662,0.02614916726068394,0.3969715892812894,2.525404913107488,-0.3430464255779581,-0.10586048643661662,-0.595242946157797,0.3801119112602281,0.11776071457762759,0.8552381999638872,1.181463958349545,0.27733733002235417,4.258503091616609,1.442407617676143,3.387308237114521,1.577900780996791,0.5775714858809151,0.870059284479323,0.5775714858809151,-0.02987854200342981,1.4045013303564935,0.31190736282418247,-0.8180718103176833,0.5615113239535318,1.085314604290465,0.25993326491209245,-0.048735570818035576,0.363176231493417,-0.18334808070797615,0.13582414108741372,0.17169755104451068,2.534393935132652,2.6489138234015064,1.9865073756421463,2.3779106499781055,1.261829326445677,1.1405784257109197,0.04464637679634543,0.6724902109286491,-0.5736141057694272,1.541480881266963,0.3801119112602281,1.1130548036372934,-0.6169874837196055,0.11776071457762759,1.1949872162647377,1.3274111687020549,0.7035921494358485,-0.2226723202632471,0.15380286431879417,1.2084584164574235,0.31190736282418247,-0.2029611534569842,0.8254121420894225,0.719044467209736,1.181463958349545,0.11776071457762759,0.22488395017924478,0.22488395017924478,1.3789958573127592,2.784180874695723,2.825233750109732,3.2426404073511974,1.3917722506837715,1.6377408954325872,0.9864762058893607,0.34616397120861425,-0.24248241020736983,-0.08672578350961495,-0.4046271871534076,3.518485936002134,0.09961191055323138,0.09961191055323138,0.795338037054623,0.4137558381966468,1.442407617676143,-0.262392262257652,-0.16383228267364128,0.31190736282418247,0.15380286431879417,0.4965652697383779,0.6880742208527362,0.8403559612194028,1.731319631584345,1.5658043187937936,-0.2029611534569842,1.5658043187937936,2.16305244697371
3,477
Serine hydrolase activity
12
20
3.155424
0.001603
P10619,P42785,Q6NTF9,Q16740,Q9H3G5,O43464,Q5JRX3,O75976,Q9HB40,O14773,Q6PIU2,P67812
Functions
GO Molecular function
msigdb_gomf
160,35,328,46,51,592,404,466,27,279,377,218
279,592,466,160,2748,2785,2002,35,1477,1643,601,218,46,864,404,328,377,1925,51,27
1.4549503603205254,0.7497541290280656,0.972129499196718,1.8558377322438417,-0.6608278481110601,-0.6829258074091615,-0.2824027254226025,3.1125140490108847,-0.011112566654353354,-0.10586048643661662,0.7344316400083396,1.649582259474987,2.865729584816768,0.4304652245976121,1.1268435085723476,1.3013270958737004,1.181463958349545,-0.24248241020736983,2.808880164855887,3.2142291593409142
3,477
Glycosphingolipid metabolism
9
16
3.154958
0.001605
P10619,Q13510,P16278,P04062,P06865,Q16739,Q9NZJ7,P07602,P06280
Processes and pathways
Reactome Pathways
msigdb_reactome
160,100,68,106,235,83,406,24,281
935,758,106,281,235,24,1287,160,1875,68,408,100,83,2361,1987,406
0.34616397120861425,0.5453811397505782,2.291773758375661,1.4549503603205254,1.613932265149701,3.2426404073511974,0.09961191055323138,1.8558377322438417,-0.2226723202632471,2.5877825531853427,1.1130548036372934,2.358972488129669,2.461737501871504,-0.4462137510231218,-0.262392262257652,1.1268435085723476
3,477
Steroid biosynthesis
9
13
3.154902
0.001606
P48449,Q15125,P38571,Q15800,Q14534,P37268,O76062,Q16850,Q15392
Processes and pathways
KEGG Pathways
msigdb_kegg
217,167,232,141,175,117,274,153,126
375,274,2507,117,232,217,175,167,126,883,141,153,1988
1.181463958349545,1.4674472355220745,-0.5306993975719276,2.142778735840569,1.6258576473578923,1.649582259474987,1.7771424058672443,1.8110987672570336,2.0811764381859885,0.4137558381966468,2.0077854950437413,1.9218252181935185,-0.262392262257652
3,477
Sphingolipid biosynthetic process
11
20
3.134731
0.00172
Q96G23,Q13510,O15121,O95470,P04062,P27544,Q16739,Q9P035,Q53H12,Q99805,Q06136
Processes and pathways
GO Biological process
msigdb_gobp
324,100,133,105,106,124,83,437,442,223,219
133,542,1018,105,106,2505,2047,124,1960,219,100,83,442,2640,324,223,839,1987,437,1492
2.0394430613633685,0.8254121420894225,0.27733733002235417,2.3014619358985096,2.291773758375661,-0.5306993975719276,-0.3025146589063486,2.0915258852348777,-0.262392262257652,1.649582259474987,2.358972488129669,2.461737501871504,1.0432918958486117,-0.595242946157797,1.3143936999272097,1.649582259474987,0.4636616464692855,-0.262392262257652,1.0573549420901271,-0.011112566654353354
3,477
Parkinsons disease
26
59
3.127276
0.001764
O75306,O96000,P14406,P31930,P00403,P45880,O43676,P00846,P21796,P13073,P12236,P14927,Q9UDW1,O43920,P12235,O95168,P24539,O95169,O43464,O14548,O14949,Q9Y6M9,P20674,Q9Y277,P05141,P21912
Processes and pathways
KEGG Pathways
msigdb_kegg
128,510,5,643,258,12,19,20,23,159,418,301,50,561,457,582,339,82,592,351,109,116,628,250,627,125
920,351,109,592,1000,19,3365,561,1995,128,1498,1355,1283,582,82,3416,890,510,258,20,903,3418,627,655,830,1316,457,418,159,5,1874,301,2091,1828,628,23,125,3260,731,339,1569,3393,2667,643,942,2545,12,2173,3249,861,3098,2429,2933,1341,971,3362,50,250,116
0.363176231493417,1.2352459870262076,2.252720884481982,0.7497541290280656,0.29466182574769184,3.3399034479628043,-1.3808477342331456,0.795338037054623,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,0.04464637679634543,0.09961191055323138,0.7650123908871262,2.461737501871504,-1.6506750213514003,0.3969715892812894,0.8848196367866663,1.5169816611056757,3.333065755789585,0.3801119112602281,-1.6785966185631933,0.7035921494358485,0.6724902109286491,0.4636616464692855,0.08137704720652839,1.0149975096355603,1.085314604290465,1.866928176818198,3.8385255731536114,-0.2226723202632471,1.3789958573127592,-0.3227289322669874,-0.2029611534569842,0.7035921494358485,3.284733395150704,2.0811764381859885,-1.1269078629663312,0.5775714858809151,1.261829326445677,-0.06768439960582033,-1.4867799433989366,-0.6169874837196055,0.6880742208527362,0.34616397120861425,-0.5520999295887415,3.5880722275384778,-0.3634680295925095,-1.1023275684761824,0.4304652245976121,-0.9106897973314252,-0.48823524922289674,-0.7725283500753476,0.0630554350483885,0.3290745454164685,-1.3547654978043482,2.825233750109732,1.5536644399111408,2.16305244697371
3,477
Cellular transition metal ion homeostasis
11
23
3.123979
0.001784
O75027,P02794,Q15043,P05067,P09601,Q15904,O75880,Q8N511,Q8NEW0,Q9Y487,Q9Y5Y0
Processes and pathways
GO Biological process
msigdb_gobp
129,192,164,134,41,270,304,79,114,123,189
2695,3273,573,2237,129,2464,304,3368,1163,192,134,41,2819,2622,326,2048,1438,164,270,79,114,123,189
-0.6388487645543015,-1.1516317262366567,0.7802068776839349,-0.4046271871534076,2.0603772329418755,-0.5094115023895259,1.3661718533156093,-1.3808477342331456,0.17169755104451068,1.7081694282043638,2.0394430613633685,2.9762603054079118,-0.7051437292628466,-0.595242946157797,1.3013270958737004,-0.3025146589063486,0.007563093228499072,1.8335441178353415,1.4798985250540877,2.4982794163821613,2.16305244697371,2.101842136086416,1.731319631584345
3,477
Respiratory failure
25
69
3.093794
0.001976
O75306,Q9H9S5,Q9NZJ7,P33991,P07602,Q5XKP0,Q9BT22,P61916,Q9NX14,P40939,O43819,Q15165,Q8N183,P53701,O95169,O43464,Q92804,P23786,Q13510,P35637,Q96B26,Q9NSD9,Q9Y619,P10253,Q70HW3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,402,406,275,24,287,163,420,552,553,573,197,587,204,82,592,349,93,100,369,242,115,247,121,122
592,573,2536,128,1675,2133,1430,82,1532,1252,24,3301,977,121,1909,3276,3121,3369,3410,93,275,369,553,2003,981,2546,1915,2859,2902,204,2862,2753,1148,420,1760,794,100,1293,197,820,2635,1483,287,122,2484,587,1266,606,2764,1203,1414,349,242,915,2221,163,1896,2999,755,801,402,1327,115,552,406,1937,1865,247,3425
0.7497541290280656,0.7802068776839349,-0.5520999295887415,2.0707936146461794,-0.12508928118991622,-0.3430464255779581,0.007563093228499072,2.461737501871504,-0.048735570818035576,0.11776071457762759,3.2426404073511974,-1.2015158504193209,0.31190736282418247,2.1121253696676408,-0.24248241020736983,-1.1516317262366567,-0.9341703246969754,-1.3808477342331456,-1.5953583578858173,2.396734762422103,1.4674472355220745,1.1949872162647377,0.8104063122296249,-0.2824027254226025,0.31190736282418247,-0.5520999295887415,-0.24248241020736983,-0.7274827145107601,-0.7499438782500567,1.6731403254770958,-0.7274827145107601,-0.6608278481110601,0.18950886067998413,1.085314604290465,-0.16383228267364128,0.5129086364034002,2.358972488129669,0.09961191055323138,1.6965338049214893,0.4801497856111335,-0.595242946157797,-0.011112566654353354,1.442407617676143,2.101842136086416,-0.5094115023895259,0.7650123908871262,0.11776071457762759,0.7344316400083396,-0.6608278481110601,0.15380286431879417,0.02614916726068394,1.2485630214820864,1.5899540873792353,0.3801119112602281,-0.3839946459113293,1.8447097839425666,-0.2226723202632471,-0.8180718103176833,0.5615113239535318,0.5129086364034002,1.1405784257109197,0.08137704720652839,2.16305244697371,0.8254121420894225,1.1268435085723476,-0.24248241020736983,-0.2029611534569842,1.5658043187937936,-1.6785966185631933
3,477
Carbohydrate derivative transport
14
19
3.091898
0.001989
P12236,O00400,P41440,Q8TB61,P61916,Q8WTV0,P12235,Q6NUK1,Q96AA3,Q08722,Q9NZJ7,P07602,P05141,Q9HC21
Processes and pathways
GO Biological process
msigdb_gobp
418,312,388,132,420,71,457,429,662,750,406,24,627,414
1389,312,803,1282,627,24,457,418,388,420,750,429,2358,132,71,662,1520,414,406
0.02614916726068394,1.3274111687020549,0.4965652697383779,0.09961191055323138,0.7035921494358485,3.2426404073511974,1.0149975096355603,1.085314604290465,1.1678883030223781,1.085314604290465,0.5615113239535318,1.071362388503744,-0.4462137510231218,2.0603772329418755,2.5700894098740656,0.6724902109286491,-0.02987854200342981,1.1130548036372934,1.1268435085723476
3,477
Transition metal ion transport
9
16
3.090153
0.002001
O75027,P02794,Q15043,Q9HD20,O15173,Q8NEW0,Q8N4V1,P98194,Q9Y5Y0
Processes and pathways
GO Biological process
msigdb_gobp
129,192,164,101,104,114,56,186,189
104,129,1163,192,326,1641,186,2959,2392,734,164,56,114,667,101,189
2.311120407130275,2.0603772329418755,0.17169755104451068,1.7081694282043638,1.3013270958737004,-0.10586048643661662,1.731319631584345,-0.7952372743225334,-0.4671696555646836,0.5775714858809151,1.8335441178353415,2.7676008494517013,2.16305244697371,0.6724902109286491,2.358972488129669,1.731319631584345
3,477
Proton transporting two sector atpase complex proton transporting domain
6
11
3.086332
0.002026
O75964,Q93050,P24539,P00846,P56385,Q9Y487
Localization
GO Cellular component
msigdb_gocc
32,17,339,20,283,123
386,1283,32,20,339,2173,845,283,1438,17,123
1.1678883030223781,0.09961191055323138,3.141943931656318,3.333065755789585,1.261829326445677,-0.3634680295925095,0.4471003091088909,1.4549503603205254,0.007563093228499072,3.373845322764859,2.101842136086416
3,477
Organic acid transport
20
48
3.081146
0.002062
P41440,P50416,Q9BQT8,Q9H2D1,Q15041,P31751,O60831,P30825,Q9UBX3,Q6P4A7,Q9UJS0,O75746,P08183,O43772,P23786,Q9H2J7,P53985,Q9Y3D6,Q9Y619,Q96NB2
Processes and pathways
GO Biological process
msigdb_gobp
388,394,522,143,536,426,425,307,54,67,465,593,211,215,93,229,489,372,247,380
1942,803,215,1282,425,593,813,1431,1222,1870,1825,1143,2950,211,922,1067,2468,2926,93,1048,1503,307,1117,426,1436,1049,388,394,1599,489,790,3451,943,536,863,1582,67,2358,380,522,143,229,667,54,465,957,372,247
-0.262392262257652,0.4965652697383779,1.649582259474987,0.09961191055323138,1.071362388503744,0.7497541290280656,0.4801497856111335,0.007563093228499072,0.13582414108741372,-0.2226723202632471,-0.2029611534569842,0.18950886067998413,-0.7952372743225334,1.6613819875037117,0.363176231493417,0.24244901301698119,-0.5094115023895259,-0.7725283500753476,2.396734762422103,0.25993326491209245,-0.02987854200342981,1.3532999391374014,0.2072374453876056,1.071362388503744,0.007563093228499072,0.25993326491209245,1.1678883030223781,1.1542599074685331,-0.08672578350961495,0.9287404597149378,0.5129086364034002,-2.11991428298489,0.34616397120861425,0.8403559612194028,0.4304652245976121,-0.06768439960582033,2.6402555038244877,-0.4462137510231218,1.181463958349545,0.870059284479323,1.9865073756421463,1.6377408954325872,0.6724902109286491,2.784180874695723,0.9864762058893607,0.34616397120861425,1.1949872162647377,1.5658043187937936
3,477
Sterol metabolic process
17
42
3.079421
0.002074
P48449,P05067,Q15125,Q8WTV0,P38571,P04062,Q15800,O15118,Q14534,P04035,P37268,O76062,Q16850,O75845,Q14739,Q15392,Q9BQE5
Processes and pathways
GO Biological process
msigdb_gobp
217,134,167,71,232,106,141,142,175,210,117,274,153,375,187,126,62
142,875,375,693,274,1142,1534,210,106,134,1164,815,488,2664,1191,2507,117,232,3016,217,3419,2795,2796,420,3219,2755,3380,175,187,3254,2396,167,3200,126,883,141,153,71,62,1988,1621,1016
1.9865073756421463,0.4137558381966468,1.181463958349545,0.6253369160329553,1.4674472355220745,0.18950886067998413,-0.048735570818035576,1.6613819875037117,2.291773758375661,2.0394430613633685,0.17169755104451068,0.4801497856111335,0.9287404597149378,-0.6169874837196055,0.15380286431879417,-0.5306993975719276,2.142778735840569,1.6258576473578923,-0.8410331326310951,1.649582259474987,-1.6785966185631933,-0.6829258074091615,-0.6829258074091615,1.085314604290465,-1.053592111071168,-0.6608278481110601,-1.4070886524662474,1.7771424058672443,1.731319631584345,-1.1023275684761824,-0.4671696555646836,1.8110987672570336,-1.0294342081393086,2.0811764381859885,0.4137558381966468,2.0077854950437413,1.9218252181935185,2.5700894098740656,2.6833023859483847,-0.262392262257652,-0.08672578350961495,0.29466182574769184
3,477
Proton transporting two sector atpase complex
8
24
3.078496
0.00208
O75964,Q15904,Q8N511,Q93050,P24539,P00846,P56385,Q9Y487
Localization
GO Cellular component
msigdb_gocc
32,270,79,17,339,20,283,123
2464,386,1283,32,20,655,858,2898,339,1569,942,843,2048,2173,845,283,1438,270,79,17,533,1279,123,1311
-0.5094115023895259,1.1678883030223781,0.09961191055323138,3.141943931656318,3.333065755789585,0.6724902109286491,0.4304652245976121,-0.7499438782500567,1.261829326445677,-0.06768439960582033,0.34616397120861425,0.4471003091088909,-0.3025146589063486,-0.3634680295925095,0.4471003091088909,1.4549503603205254,0.007563093228499072,1.4798985250540877,2.4982794163821613,3.373845322764859,0.8552381999638872,0.11776071457762759,2.101842136086416,0.09961191055323138
3,477
Vacuole organization
21
56
3.067913
0.002156
O75787,Q9Y371,Q8WVM8,P54802,Q14108,Q9H0U4,P50897,O14773,Q7Z3C6,P11117,O75503,Q8N511,Q9H270,Q96ED9,Q6UWE0,P16615,P04062,Q12768,Q86Y82,P10253,Q9P253
Processes and pathways
GO Biological process
msigdb_gobp
386,785,781,140,14,665,26,279,161,165,47,79,610,87,475,231,106,735,751,121,517
873,2695,279,1064,47,386,1284,1161,106,1567,1287,121,165,231,2243,1836,2423,26,2247,140,1793,1794,1318,735,14,2804,1647,2762,1096,475,161,751,79,1152,781,1324,87,1132,2688,665,2648,610,2073,809,1743,1246,517,2124,1468,2844,1589,1937,785,1387,958,3244
0.4137558381966468,-0.6388487645543015,1.4549503603205254,0.24244901301698119,2.8495972795541524,1.1678883030223781,0.09961191055323138,0.17169755104451068,2.291773758375661,-0.06768439960582033,0.09961191055323138,2.1121253696676408,1.8223405181207388,1.6258576473578923,-0.4046271871534076,-0.2029611534569842,-0.48823524922289674,3.2355640449184544,-0.4046271871534076,2.0077854950437413,-0.18334808070797615,-0.18334808070797615,0.08137704720652839,0.5775714858809151,3.4206854913567066,-0.6829258074091615,-0.10586048643661662,-0.6608278481110601,0.22488395017924478,0.9577249028843212,1.8558377322438417,0.5615113239535318,2.4982794163821613,0.18950886067998413,0.5291804175825732,0.08137704720652839,2.4247596038681953,0.2072374453876056,-0.6169874837196055,0.6724902109286491,-0.595242946157797,0.7344316400083396,-0.3025146589063486,0.4965652697383779,-0.14441294960249149,0.13582414108741372,0.8848196367866663,-0.3227289322669874,0.007563093228499072,-0.7051437292628466,-0.06768439960582033,-0.24248241020736983,0.5291804175825732,0.04464637679634543,0.34616397120861425,-1.077889444304914
3,477
Cristae formation
12
21
3.062735
0.002193
O75964,Q13505,Q9Y512,Q9BUR5,Q6UXV4,P24539,P00846,Q16891,Q9NX63,P17152,P56385,Q5XKP0
Processes and pathways
Reactome Pathways
msigdb_reactome
32,353,650,421,299,339,20,341,383,504,283,287
749,1283,32,20,655,504,339,1569,942,2099,2173,845,283,353,341,287,299,421,1211,383,650
0.5615113239535318,0.09961191055323138,3.141943931656318,3.333065755789585,0.6724902109286491,0.8995196748229518,1.261829326445677,-0.06768439960582033,0.34616397120861425,-0.3227289322669874,-0.3634680295925095,0.4471003091088909,1.4549503603205254,1.2352459870262076,1.261829326445677,1.442407617676143,1.3917722506837715,1.085314604290465,0.15380286431879417,1.181463958349545,0.6880742208527362
3,477
Azurophil granule membrane
9
20
3.053472
0.002262
P10253,P42785,Q07065,Q9NQX7,Q9NZJ7,Q92542,P07602,Q8NF37,O15260
Localization
GO Cellular component
msigdb_gocc
121,35,233,334,406,379,24,284,374
374,3088,1786,639,24,121,482,1475,35,1916,1022,233,1096,284,379,1299,1014,334,406,1492
1.181463958349545,-0.9106897973314252,-0.18334808070797615,0.6880742208527362,3.2426404073511974,2.1121253696676408,0.9432620224784491,-0.011112566654353354,3.1125140490108847,-0.24248241020736983,0.27733733002235417,1.6258576473578923,0.22488395017924478,1.4549503603205254,1.181463958349545,0.09961191055323138,0.29466182574769184,1.2882110433921183,1.1268435085723476,-0.011112566654353354
3,477
Sphingolipid metabolism
7
13
3.052431
0.00227
Q13510,P16278,O15121,O95470,P04062,Q16739,Q06136
Processes and pathways
KEGG Pathways
msigdb_kegg
100,68,133,105,106,83,219
133,542,1018,758,105,106,281,1875,68,219,100,83,1987
2.0394430613633685,0.8254121420894225,0.27733733002235417,0.5453811397505782,2.3014619358985096,2.291773758375661,1.4549503603205254,-0.2226723202632471,2.5877825531853427,1.649582259474987,2.358972488129669,2.461737501871504,-0.262392262257652
3,477
Secondary active transmembrane transporter activity
19
23
3.044903
0.002328
P41440,Q9BXP2,O95202,Q8NE86,P55011,P12236,Q15043,P08195,Q9Y289,Q9UBX3,O00400,P12235,P51798,Q96ES6,Q15758,Q9H2J7,P53985,P51790,P05141
Functions
GO Molecular function
msigdb_gomf
388,916,139,547,790,418,164,922,957,54,312,457,586,722,863,229,489,108,627
312,139,3092,627,922,457,418,388,108,586,1599,489,790,1050,943,164,863,547,722,916,229,54,957
1.3274111687020549,2.0077854950437413,-0.9106897973314252,0.7035921494358485,0.363176231493417,1.0149975096355603,1.085314604290465,1.1678883030223781,2.2625294404559577,0.7650123908871262,-0.08672578350961495,0.9287404597149378,0.5129086364034002,0.25993326491209245,0.34616397120861425,1.8335441178353415,0.4304652245976121,0.8254121420894225,0.5935621359363286,0.3801119112602281,1.6377408954325872,2.784180874695723,0.34616397120861425
3,477
Golgi membrane
47
146
3.043995
0.002335
Q96L58,O43505,Q8TB61,Q9H7Z7,Q9Y282,Q8N6G5,Q14108,P24390,Q9H9S5,Q9Y5Z9,P35613,Q8NF37,Q16799,Q10713,Q7Z3C6,Q8NBN3,Q9BUR5,O95197,O00461,Q10472,Q8N4V1,O00400,O43731,P98194,P49755,P01889,Q7LGA3,P35670,Q6NTF9,Q8IV08,Q9NTJ5,O60499,Q15363,Q16739,Q9Y3B3,Q8TBA6,Q92896,Q9H4A6,Q8NCH0,O95070,P51790,P10321,O95249,Q8IZA0,O15260,Q15392,Q9P2W9
Localization
GO Cellular component
msigdb_gocc
256,384,132,262,9,137,14,15,402,148,409,284,29,416,161,295,421,39,172,305,56,312,58,186,441,446,322,326,328,202,461,330,81,83,338,254,221,350,95,216,108,364,240,119,374,126,127
1389,312,172,2129,3273,1868,748,374,2273,384,2370,58,2889,330,2946,1064,216,39,240,639,446,468,1225,2199,364,1067,788,774,2047,15,2001,409,326,2954,2333,1836,2286,3413,694,441,1641,585,108,816,1600,3124,3018,1147,1793,2140,2627,1070,966,1794,1541,1756,1318,1958,186,657,1193,818,1230,1401,1758,305,3099,416,793,1124,984,967,14,881,2804,3100,2056,81,1763,126,1764,2762,83,29,328,710,322,161,3267,751,202,119,56,137,1201,1150,295,95,1238,284,132,254,781,2309,2067,221,531,3136,256,607,421,1013,3309,1854,665,2260,1209,350,262,3401,402,1462,1857,461,1987,1492,716,127,2885,2694,2410,918,3084,1935,701,1525,9,2230,2269,2847,785,338,2777,1312,148,2615
0.02614916726068394,1.3274111687020549,1.7771424058672443,-0.3430464255779581,-1.1516317262366567,-0.2226723202632471,0.5615113239535318,1.181463958349545,-0.42536657713018505,1.1678883030223781,-0.4671696555646836,2.72574613566304,-0.7499438782500567,1.2882110433921183,-0.7952372743225334,0.24244901301698119,1.649582259474987,3.0223888856624046,1.5899540873792353,0.6880742208527362,1.029172877098212,0.972129499196718,0.13582414108741372,-0.3839946459113293,1.2084584164574235,0.24244901301698119,0.5129086364034002,0.5291804175825732,-0.3025146589063486,3.394015562843155,-0.2824027254226025,1.1130548036372934,1.3013270958737004,-0.7952372743225334,-0.4462137510231218,-0.2029611534569842,-0.42536657713018505,-1.622929555485722,0.6253369160329553,1.0432918958486117,-0.10586048643661662,0.7650123908871262,2.2625294404559577,0.4801497856111335,-0.08672578350961495,-0.9341703246969754,-0.8410331326310951,0.18950886067998413,-0.18334808070797615,-0.3430464255779581,-0.595242946157797,0.24244901301698119,0.3290745454164685,-0.18334808070797615,-0.048735570818035576,-0.16383228267364128,0.08137704720652839,-0.262392262257652,1.731319631584345,0.6724902109286491,0.15380286431879417,0.4801497856111335,0.13582414108741372,0.02614916726068394,-0.16383228267364128,1.3661718533156093,-0.9106897973314252,1.0992119552130728,0.5129086364034002,0.2072374453876056,0.31190736282418247,0.3290745454164685,3.4206854913567066,0.4137558381966468,-0.6829258074091615,-0.9106897973314252,-0.3025146589063486,2.470913514380328,-0.16383228267364128,2.0811764381859885,-0.16383228267364128,-0.6608278481110601,2.461737501871504,3.19991699449962,1.3013270958737004,0.6094837793071348,1.3143936999272097,1.8558377322438417,-1.1269078629663312,0.5615113239535318,1.6848575173151885,2.1325934939744515,2.7676008494517013,2.018372441939004,0.15380286431879417,0.18950886067998413,1.4045013303564935,2.396734762422103,0.13582414108741372,1.4549503603205254,2.0603772329418755,1.541480881266963,0.5291804175825732,-0.42536657713018505,-0.3025146589063486,1.649582259474987,0.8552381999638872,-0.9341703246969754,1.5292533775321773,0.7344316400083396,1.085314604290465,0.29466182574769184,-1.2015158504193209,-0.2029611534569842,0.6724902109286491,-0.4046271871534076,0.15380286431879417,1.2485630214820864,1.5169816611056757,-1.5136721546532035,1.1405784257109197,0.007563093228499072,-0.2029611534569842,1.000765413691891,-0.262392262257652,-0.011112566654353354,0.6094837793071348,2.0811764381859885,-0.7274827145107601,-0.6169874837196055,-0.4671696555646836,0.3801119112602281,-0.8873409122764672,-0.24248241020736983,0.6253369160329553,-0.02987854200342981,3.7751451557105193,-0.3839946459113293,-0.4046271871534076,-0.7051437292628466,0.5291804175825732,1.2750452265193046,-0.6608278481110601,0.09961191055323138,1.9650890031069095,-0.5736141057694272
3,477
Ion channel transport
11
32
3.036497
0.002393
P05023,Q4KMQ2,P35670,Q9HD20,P16615,P51790,Q15904,Q93050,P98194,Q9Y487,Q9C0H2
Processes and pathways
Reactome Pathways
msigdb_reactome
291,389,326,101,231,108,270,17,186,123,31
2464,291,231,447,858,2898,877,2622,326,843,2048,108,586,1023,1438,186,1028,719,1480,3390,270,389,1202,17,1976,808,31,2649,101,1279,123,1311
-0.5094115023895259,1.4171833906612892,1.6258576473578923,1.029172877098212,0.4304652245976121,-0.7499438782500567,0.4137558381966468,-0.595242946157797,1.3013270958737004,0.4471003091088909,-0.3025146589063486,2.2625294404559577,0.7650123908871262,0.27733733002235417,0.007563093228499072,1.731319631584345,0.27733733002235417,0.5935621359363286,-0.011112566654353354,-1.4600530886095953,1.4798985250540877,1.1678883030223781,0.15380286431879417,3.373845322764859,-0.262392262257652,0.4965652697383779,3.1783138805528677,-0.595242946157797,2.358972488129669,0.11776071457762759,2.101842136086416,0.09961191055323138
3,477
Muscle abnormality related to mitochondrial dysfunction
17
38
3.034992
0.002405
O75306,Q9Y375,Q9NX14,Q9BUK6,O96000,P00403,Q86Y39,P12235,Q9Y2R0,Q96CU9,O43676,P00846,Q9NPL8,Q53H12,O60313,Q9UBX3,Q9Y6M9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,289,552,292,510,258,193,457,13,77,19,20,371,442,308,54,116
920,19,308,1995,128,1498,1355,510,258,20,903,3418,457,1874,1828,3393,2003,3249,2549,2902,442,193,587,894,2561,77,3423,2999,292,371,552,1108,54,13,1386,289,1940,116
0.363176231493417,3.3399034479628043,1.3403798125660904,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,0.04464637679634543,0.8848196367866663,1.5169816611056757,3.333065755789585,0.3801119112602281,-1.6785966185631933,1.0149975096355603,-0.2226723202632471,-0.2029611534569842,-1.4867799433989366,-0.2824027254226025,-1.1023275684761824,-0.5520999295887415,-0.7499438782500567,1.0432918958486117,1.7081694282043638,0.7650123908871262,0.3969715892812894,-0.5520999295887415,2.525404913107488,-1.6785966185631933,-0.8180718103176833,1.4171833906612892,1.1949872162647377,0.8254121420894225,0.22488395017924478,2.784180874695723,3.518485936002134,0.04464637679634543,1.442407617676143,-0.24248241020736983,2.16305244697371
3,477
Glycerophospholipid biosynthesis
16
33
3.030995
0.002437
Q92604,Q6UWP7,Q9NQZ5,Q8NAN2,P43304,Q9NPH0,Q96N66,P35790,Q8IV08,Q9UG56,Q9HCL2,P40939,Q53H12,Q9HBU6,Q8NF37,Q8NCC3
Processes and pathways
Reactome Pathways
msigdb_reactome
739,578,354,711,644,6,296,410,202,300,110,553,442,88,284,59
1707,727,3088,938,2663,410,553,644,2049,3413,2753,1439,1397,442,578,1487,202,2685,711,59,284,1450,739,1268,296,1039,1040,88,110,6,354,1277,300
-0.14441294960249149,0.5775714858809151,-0.9106897973314252,0.34616397120861425,-0.6169874837196055,1.1130548036372934,0.8104063122296249,0.6880742208527362,-0.3025146589063486,-1.622929555485722,-0.6608278481110601,0.007563093228499072,0.02614916726068394,1.0432918958486117,0.7802068776839349,-0.011112566654353354,1.6848575173151885,-0.6169874837196055,0.6094837793071348,2.7173049529486404,1.4549503603205254,0.007563093228499072,0.5775714858809151,0.11776071457762759,1.4045013303564935,0.27733733002235417,0.27733733002235417,2.4247596038681953,2.2330121466283503,3.8099023828488017,1.2352459870262076,0.11776071457762759,1.3917722506837715
3,477
Cardiac muscle contraction
8
19
3.029483
0.00245
P05023,P14406,P00403,P16615,P14927,O14949,Q9UDW1,P13073
Processes and pathways
KEGG Pathways
msigdb_kegg
291,5,258,231,301,109,50,159
351,109,258,291,1252,830,1316,159,5,1874,301,2091,231,628,731,643,1023,1025,50
1.2352459870262076,2.252720884481982,1.5169816611056757,1.4171833906612892,0.11776071457762759,0.4636616464692855,0.08137704720652839,1.866928176818198,3.8385255731536114,-0.2226723202632471,1.3789958573127592,-0.3227289322669874,1.6258576473578923,0.7035921494358485,0.5775714858809151,0.6880742208527362,0.27733733002235417,0.27733733002235417,2.825233750109732
3,477
Cholesterol biosynthesis
11
20
3.016456
0.002557
P48449,Q15125,Q15800,Q14534,P04035,P37268,O76062,Q16850,Q14739,Q15392,Q9BWD1
Processes and pathways
Reactome Pathways
msigdb_reactome
217,167,141,175,210,117,274,153,187,126,57
375,274,1533,210,815,117,217,2796,2755,3380,175,187,167,3200,126,883,141,153,57,1988
1.181463958349545,1.4674472355220745,-0.048735570818035576,1.6613819875037117,0.4801497856111335,2.142778735840569,1.649582259474987,-0.6829258074091615,-0.6608278481110601,-1.4070886524662474,1.7771424058672443,1.731319631584345,1.8110987672570336,-1.0294342081393086,2.0811764381859885,0.4137558381966468,2.0077854950437413,1.9218252181935185,2.7509287653912478,-0.262392262257652
3,477
Glycoside hydrolase superfamily [IPR017853]
7
15
3.016231
0.002559
P16278,O60502,P04062,P06865,P54802,Q9BTY2,P10253
Sequence
InterPro Superfamily
interpro_homologous_superfamily
68,103,106,235,140,182,121
103,106,717,281,235,1287,922,640,121,68,2245,140,1799,182,1930
2.320749325149068,2.291773758375661,0.5935621359363286,1.4549503603205254,1.613932265149701,0.09961191055323138,0.363176231493417,0.6880742208527362,2.1121253696676408,2.5877825531853427,-0.4046271871534076,2.0077854950437413,-0.18334808070797615,1.7543100076167693,-0.24248241020736983
3,477
Protein transporter activity
10
14
3.010109
0.002612
O60830,Q99595,Q9NS69,Q07820,Q9HD20,O14925,O96008,Q15388,P49755,Q8NBU5
Functions
GO Molecular function
msigdb_gomf
0,1,2,451,101,173,527,463,441,606
873,173,0,1633,527,441,1170,451,463,606,1,101,2,637
0.4137558381966468,1.7771424058672443,4.258503091616609,-0.10586048643661662,0.8552381999638872,1.0432918958486117,0.17169755104451068,1.029172877098212,0.9864762058893607,0.7344316400083396,4.258503091616609,2.358972488129669,4.030663110153479,0.7035921494358485
3,477
Biliary tract abnormality
10
27
3.000896
0.002692
P09601,P04062,O95202,Q14108,O96028,Q9NSD9,Q9NZJ7,P07602,Q14739,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
41,106,139,14,331,115,406,24,187,287
758,139,331,1251,106,24,41,2468,1875,3357,2002,2207,1226,416,1403,3163,14,187,287,2220,3224,1491,115,406,638,1938,2194
0.5453811397505782,2.0077854950437413,1.2882110433921183,0.11776071457762759,2.291773758375661,3.2426404073511974,2.9762603054079118,-0.5094115023895259,-0.2226723202632471,-1.3547654978043482,-0.2824027254226025,-0.3839946459113293,0.13582414108741372,1.0992119552130728,0.02614916726068394,-0.9815313424120201,3.4206854913567066,1.731319631584345,1.442407617676143,-0.3839946459113293,-1.053592111071168,-0.011112566654353354,2.16305244697371,1.1268435085723476,0.7035921494358485,-0.24248241020736983,-0.3634680295925095
3,477
Translocation
13
46
2.99892
0.002709
O60830,Q99595,Q9NS69,P41208,Q99442,Q9BTX1,Q15629,O43615,O14925,O75381,Q9Y5L4,Q3ZCQ8,Q8NFH4
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,1,2,196,588,166,69,454,173,362,541,537,378
1941,173,1111,454,1629,0,362,1356,2135,1145,962,196,2548,1361,1643,1069,1917,1170,3252,2593,1094,69,537,2635,1097,616,1413,378,1203,1239,1489,3343,1451,1700,588,741,1,166,1978,1459,756,2,2884,1620,1562,541
-0.262392262257652,1.7771424058672443,0.2072374453876056,1.0149975096355603,-0.10586048643661662,4.258503091616609,1.2084584164574235,0.04464637679634543,-0.3430464255779581,0.18950886067998413,0.3290745454164685,1.6965338049214893,-0.5520999295887415,0.04464637679634543,-0.10586048643661662,0.24244901301698119,-0.24248241020736983,0.17169755104451068,-1.1023275684761824,-0.5736141057694272,0.22488395017924478,2.5877825531853427,0.8403559612194028,-0.595242946157797,0.22488395017924478,0.719044467209736,0.02614916726068394,1.181463958349545,0.15380286431879417,0.13582414108741372,-0.011112566654353354,-1.3030706558113276,0.007563093228499072,-0.12508928118991622,0.7650123908871262,0.5775714858809151,4.258503091616609,1.8223405181207388,-0.262392262257652,0.007563093228499072,0.5615113239535318,4.030663110153479,-0.7274827145107601,-0.08672578350961495,-0.048735570818035576,0.8403559612194028
3,477
Cholesterol metabolism with bloch and kandutschrussell pathways
12
27
2.996624
0.00273
P48449,Q15125,Q15800,Q14534,P04035,P37268,O76062,Q16850,O75845,Q14739,Q15392,Q9BWD1
Processes and pathways
WikiPathways
msigdb_wp
217,167,141,175,210,117,274,153,375,187,126,57
3392,1565,375,274,1222,1533,435,210,815,1436,2507,117,217,1335,2796,2755,3380,175,187,167,3200,126,883,141,153,57,1988
-1.4867799433989366,-0.06768439960582033,1.181463958349545,1.4674472355220745,0.13582414108741372,-0.048735570818035576,1.0573549420901271,1.6613819875037117,0.4801497856111335,0.007563093228499072,-0.5306993975719276,2.142778735840569,1.649582259474987,0.0630554350483885,-0.6829258074091615,-0.6608278481110601,-1.4070886524662474,1.7771424058672443,1.731319631584345,1.8110987672570336,-1.0294342081393086,2.0811764381859885,0.4137558381966468,2.0077854950437413,1.9218252181935185,2.7509287653912478,-0.262392262257652
3,477
Alzheimers disease
24
63
2.99061
0.002784
O75306,O96000,P31930,P05067,P00403,P14406,O43676,P00846,P0DP25,P13073,P14927,Q9UDW1,O43920,O95168,P24539,O95169,O14548,P14735,P16615,O14949,Q9Y6M9,Q92542,P20674,P21912
Processes and pathways
KEGG Pathways
msigdb_kegg
128,510,643,134,258,5,19,20,656,159,301,50,561,582,339,82,351,503,231,109,116,379,628,125
920,351,109,1000,19,3365,561,1995,128,1498,1355,1283,582,82,3416,890,510,258,20,3007,134,655,1826,830,656,1316,159,5,503,1874,301,2091,231,3142,1828,628,125,731,339,1569,2542,3393,2386,2667,643,942,2545,2173,1335,3249,2174,861,706,2594,2904,2013,2933,1341,379,2158,50,2410,116
0.363176231493417,1.2352459870262076,2.252720884481982,0.29466182574769184,3.3399034479628043,-1.3808477342331456,0.795338037054623,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,0.04464637679634543,0.09961191055323138,0.7650123908871262,2.461737501871504,-1.6506750213514003,0.3969715892812894,0.8848196367866663,1.5169816611056757,3.333065755789585,-0.8410331326310951,2.0394430613633685,0.6724902109286491,-0.2029611534569842,0.4636616464692855,0.6724902109286491,0.08137704720652839,1.866928176818198,3.8385255731536114,0.8995196748229518,-0.2226723202632471,1.3789958573127592,-0.3227289322669874,1.6258576473578923,-0.9577837491650766,-0.2029611534569842,0.7035921494358485,2.0811764381859885,0.5775714858809151,1.261829326445677,-0.06768439960582033,-0.5520999295887415,-1.4867799433989366,-0.4671696555646836,-0.6169874837196055,0.6880742208527362,0.34616397120861425,-0.5520999295887415,-0.3634680295925095,0.0630554350483885,-1.1023275684761824,-0.3634680295925095,0.4304652245976121,0.6094837793071348,-0.5736141057694272,-0.7499438782500567,-0.2824027254226025,-0.7725283500753476,0.0630554350483885,1.181463958349545,-0.3430464255779581,2.825233750109732,-0.4671696555646836,2.16305244697371
3,477
Golgi stack
19
37
2.98929
0.002796
Q96L58,Q8WVM8,Q8N6G5,Q10713,Q8NBN3,O00461,Q10472,P98194,Q9P2E5,P51572,Q15363,P04439,Q9Y6B6,Q9H4A6,Q8NBZ7,O95249,Q8WVQ1,Q99523,Q8TBA6
Localization
GO Cellular component
msigdb_gocc
256,781,137,416,295,172,305,186,716,585,81,468,747,350,487,240,241,496,254
172,2946,240,468,2199,2472,585,1794,186,2340,1193,818,1401,1758,305,416,881,2056,81,2762,137,295,487,254,781,241,256,496,3033,2189,350,716,1935,1589,2230,1527,747
1.7771424058672443,-0.7952372743225334,1.5899540873792353,0.972129499196718,-0.3839946459113293,-0.5094115023895259,0.7650123908871262,-0.18334808070797615,1.731319631584345,-0.4462137510231218,0.15380286431879417,0.4801497856111335,0.02614916726068394,-0.16383228267364128,1.3661718533156093,1.0992119552130728,0.4137558381966468,-0.3025146589063486,2.470913514380328,-0.6608278481110601,2.018372441939004,1.4045013303564935,0.9432620224784491,1.541480881266963,0.5291804175825732,1.5899540873792353,1.5292533775321773,0.9287404597149378,-0.8410331326310951,-0.3634680295925095,1.2485630214820864,0.6094837793071348,-0.24248241020736983,-0.06768439960582033,-0.3839946459113293,-0.02987854200342981,0.5775714858809151
3,477
Membrane trafficking regulatory protein
7
22
2.986256
0.002824
P11279,O60749,O43760,P24390,O43731,O00560,Q9P253
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
482,456,107,15,58,534,517
1247,1427,534,58,107,456,1532,482,15,1292,2016,2056,1153,781,1324,1700,2121,610,1857,1492,517,1589
0.11776071457762759,0.007563093228499072,0.8403559612194028,2.72574613566304,2.2820557203662677,1.0149975096355603,-0.048735570818035576,0.9432620224784491,3.394015562843155,0.09961191055323138,-0.2824027254226025,-0.3025146589063486,0.18950886067998413,0.5291804175825732,0.08137704720652839,-0.12508928118991622,-0.3227289322669874,0.7344316400083396,-0.2029611534569842,-0.011112566654353354,0.8848196367866663,-0.06768439960582033
3,477
Alpha/Beta hydrolase fold [IPR029058]
10
27
2.984346
0.002842
P10619,Q9NUJ1,P42785,Q8NCG7,Q8NCC3,Q9UMR5,Q9H6V9,Q9H3G5,P50897,Q9HB40
Sequence
InterPro Superfamily
interpro_homologous_superfamily
160,98,35,198,59,43,18,51,26,27
3091,2043,160,3303,2748,1191,232,35,1477,1335,26,864,3316,377,1925,506,59,198,3308,2878,3467,51,18,27,98,43,1939
-0.9106897973314252,-0.3025146589063486,1.8558377322438417,-1.2015158504193209,-0.6608278481110601,0.15380286431879417,1.6258576473578923,3.1125140490108847,-0.011112566654353354,0.0630554350483885,3.2355640449184544,0.4304652245976121,-1.2266790067653706,1.181463958349545,-0.24248241020736983,0.8995196748229518,2.7173049529486404,1.6965338049214893,-1.2015158504193209,-0.7274827145107601,-2.8555343159614752,2.808880164855887,3.367089603944026,3.2142291593409142,2.3779106499781055,2.929395606027997,-0.24248241020736983
3,477
Iron ion homeostasis
8
18
2.975511
0.002925
O75027,P02794,Q15043,P30519,P09601,Q8N511,Q9Y487,Q9Y5Y0
Processes and pathways
GO Biological process
msigdb_gobp
129,192,164,8,41,79,123,189
129,2464,3368,1163,192,2583,41,2819,8,2622,2048,1438,2342,164,270,79,123,189
2.0603772329418755,-0.5094115023895259,-1.3808477342331456,0.17169755104451068,1.7081694282043638,-0.5736141057694272,2.9762603054079118,-0.7051437292628466,3.780969419215487,-0.595242946157797,-0.3025146589063486,0.007563093228499072,-0.4462137510231218,1.8335441178353415,1.4798985250540877,2.4982794163821613,2.101842136086416,1.731319631584345
3,477
Primary active transmembrane transporter activity
26
59
2.974606
0.002934
O75306,O75027,O96000,P31930,P00403,O43676,Q5T3U5,P13073,P05023,Q9P0J0,Q9UDW1,P98194,O43920,P20020,P35670,P51798,O95168,Q15388,P08183,O95169,O14548,Q9HD20,P16615,Q9Y6M9,Q9NRK6,P20674
Functions
GO Molecular function
msigdb_gomf
128,129,510,643,258,19,155,159,291,303,50,186,561,447,326,586,582,463,211,82,351,101,231,116,634,628
920,351,803,1000,19,3365,561,129,1995,128,2464,1498,1355,582,82,3416,890,510,258,903,3418,291,655,211,830,1316,159,1874,231,1828,447,628,858,2898,877,1048,3393,643,1049,326,843,2048,3249,586,861,1438,186,3399,463,2933,1341,155,101,634,303,50,1279,1311,116
0.363176231493417,1.2352459870262076,0.4965652697383779,0.29466182574769184,3.3399034479628043,-1.3808477342331456,0.795338037054623,2.0603772329418755,-0.2824027254226025,2.0707936146461794,-0.5094115023895259,-0.02987854200342981,0.04464637679634543,0.7650123908871262,2.461737501871504,-1.6506750213514003,0.3969715892812894,0.8848196367866663,1.5169816611056757,0.3801119112602281,-1.6785966185631933,1.4171833906612892,0.6724902109286491,1.6613819875037117,0.4636616464692855,0.08137704720652839,1.866928176818198,-0.2226723202632471,1.6258576473578923,-0.2029611534569842,1.029172877098212,0.7035921494358485,0.4304652245976121,-0.7499438782500567,0.4137558381966468,0.25993326491209245,-1.4867799433989366,0.6880742208527362,0.25993326491209245,1.3013270958737004,0.4471003091088909,-0.3025146589063486,-1.1023275684761824,0.7650123908871262,0.4304652245976121,0.007563093228499072,1.731319631584345,-1.5136721546532035,0.9864762058893607,-0.7725283500753476,0.0630554350483885,1.8999766035038268,2.358972488129669,0.7035921494358485,1.3789958573127592,2.825233750109732,0.11776071457762759,0.09961191055323138,2.16305244697371
3,477
Cytochrome complex assembly
6
13
2.966819
0.003009
Q9BSK2,Q9Y2R0,Q69YU5,P53701,Q6DKK2,Q15070
Processes and pathways
GO Biological process
msigdb_gobp
297,13,28,204,152,94
573,304,204,94,1483,28,152,3031,1521,297,1897,1938,13
0.7802068776839349,1.3661718533156093,1.6731403254770958,2.396734762422103,-0.011112566654353354,3.207082017569042,1.9326950418116124,-0.8410331326310951,-0.02987854200342981,1.4045013303564935,-0.2226723202632471,-0.24248241020736983,3.518485936002134
3,477
Glycosaminoglycan metabolism
9
17
2.962669
0.00305
Q96L58,Q8TB61,P16278,Q8N6G5,P15586,P06865,P54802,Q8NCH0,Q7LGA3
Processes and pathways
Reactome Pathways
msigdb_reactome
256,132,68,137,236,235,140,95,322
1905,384,2982,1710,235,1287,640,236,68,140,322,137,95,132,256,716,2410
-0.24248241020736983,1.1678883030223781,-0.8180718103176833,-0.14441294960249149,1.613932265149701,0.09961191055323138,0.6880742208527362,1.613932265149701,2.5877825531853427,2.0077854950437413,1.3143936999272097,2.018372441939004,2.396734762422103,2.0603772329418755,1.5292533775321773,0.6094837793071348,-0.4671696555646836
3,477
Phospholipid metabolism
23
53
2.962032
0.003056
P43304,Q9NPH0,Q96PE3,P35790,Q8NF37,Q10713,Q96N66,Q9NYA4,Q9UG56,P40939,Q53H12,Q8NCC3,Q6UWP7,Q8NAN2,Q9BTU6,Q8IV08,Q9NTJ5,Q9HBU6,Q92604,Q9NQZ5,Q8IY17,Q9HCL2,Q9NZC3
Processes and pathways
Reactome Pathways
msigdb_reactome
644,6,538,410,284,416,296,559,300,553,442,59,578,711,589,202,461,88,739,354,367,110,113
2918,1707,727,3088,938,2663,2243,410,553,3143,644,2049,3413,2753,1794,1439,1397,2340,1230,416,1724,442,578,1487,202,367,2685,711,59,1697,284,1152,1450,739,1268,296,538,1518,2523,1039,589,1040,88,110,6,354,461,1277,559,113,2694,300,2229
-0.7725283500753476,-0.14441294960249149,0.5775714858809151,-0.9106897973314252,0.34616397120861425,-0.6169874837196055,-0.4046271871534076,1.1130548036372934,0.8104063122296249,-0.9577837491650766,0.6880742208527362,-0.3025146589063486,-1.622929555485722,-0.6608278481110601,-0.18334808070797615,0.007563093228499072,0.02614916726068394,-0.4462137510231218,0.13582414108741372,1.0992119552130728,-0.14441294960249149,1.0432918958486117,0.7802068776839349,-0.011112566654353354,1.6848575173151885,1.2084584164574235,-0.6169874837196055,0.6094837793071348,2.7173049529486404,-0.12508928118991622,1.4549503603205254,0.18950886067998413,0.007563093228499072,0.5775714858809151,0.11776071457762759,1.4045013303564935,0.8403559612194028,-0.02987854200342981,-0.5306993975719276,0.27733733002235417,0.7650123908871262,0.27733733002235417,2.4247596038681953,2.2330121466283503,3.8099023828488017,1.2352459870262076,1.000765413691891,0.11776071457762759,0.8104063122296249,2.173141259533925,-0.6169874837196055,1.3917722506837715,-0.3839946459113293
3,477
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
14
34
2.959997
0.003076
O15121,O15460,P30519,Q6UW02,P09601,P16435,Q15800,Q8NB78,P13674,Q14534,O95864,Q32P28,Q16850,O75845
Functions
GO Molecular function
msigdb_gomf
133,257,8,135,41,488,141,268,392,175,435,342,153,375
2272,3392,133,257,2741,1746,3089,2742,375,435,1115,41,392,488,1503,8,2425,1229,1028,175,141,153,342,1768,135,2217,912,3076,268,549,3298,2193,2412,889
-0.42536657713018505,-1.4867799433989366,2.0394430613633685,1.5169816611056757,-0.6608278481110601,-0.16383228267364128,-0.9106897973314252,-0.6608278481110601,1.181463958349545,1.0573549420901271,0.2072374453876056,2.9762603054079118,1.1542599074685331,0.9287404597149378,-0.02987854200342981,3.780969419215487,-0.48823524922289674,0.13582414108741372,0.27733733002235417,1.7771424058672443,2.0077854950437413,1.9218252181935185,1.261829326445677,-0.16383228267364128,2.0289249011183346,-0.3839946459113293,0.3801119112602281,-0.8873409122764672,1.4923045082617816,0.8254121420894225,-1.176500576169906,-0.3634680295925095,-0.4671696555646836,0.4137558381966468
3,477
Slc mediated transmembrane transport
11
23
2.952197
0.003155
P12236,O00400,Q15043,Q8TB61,Q9H2J7,P12235,Q8NEW0,P30825,Q9UBX3,P35613,Q70HW3
Processes and pathways
Reactome Pathways
msigdb_reactome
418,312,164,132,229,457,114,307,54,409,122
312,3092,627,922,1067,457,418,2622,307,409,2790,489,790,164,863,1582,122,114,132,1520,229,54,957
1.3274111687020549,-0.9106897973314252,0.7035921494358485,0.363176231493417,0.24244901301698119,1.0149975096355603,1.085314604290465,-0.595242946157797,1.3532999391374014,1.1130548036372934,-0.6829258074091615,0.9287404597149378,0.5129086364034002,1.8335441178353415,0.4304652245976121,-0.06768439960582033,2.101842136086416,2.16305244697371,2.0603772329418755,-0.02987854200342981,1.6377408954325872,2.784180874695723,0.34616397120861425
3,477
Protein transmembrane import into intracellular organelle
8
12
2.942011
0.003261
O60830,Q99595,O95831,O43615,O14925,O96008,Q15388,O75381
Processes and pathways
GO Biological process
msigdb_gobp
0,1,227,454,173,527,463,362
173,454,0,362,1633,227,527,2200,463,537,1,917
1.7771424058672443,1.0149975096355603,4.258503091616609,1.2084584164574235,-0.10586048643661662,1.6377408954325872,0.8552381999638872,-0.3839946459113293,0.9864762058893607,0.8403559612194028,4.258503091616609,0.3801119112602281
3,477
Horizontal nystagmus
8
23
2.93451
0.003341
O95831,Q9H061,P04062,Q9NZJ7,P00846,O60313,P07602,O14773
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
227,74,106,406,20,308,24,279
2695,902,279,308,1142,227,20,106,24,1089,962,1120,1393,1601,2718,1344,1738,74,424,3187,3228,406,1214
-0.6388487645543015,0.3801119112602281,1.4549503603205254,1.3403798125660904,0.18950886067998413,1.6377408954325872,3.333065755789585,2.291773758375661,3.2426404073511974,0.22488395017924478,0.3290745454164685,0.2072374453876056,0.02614916726068394,-0.08672578350961495,-0.6388487645543015,0.0630554350483885,-0.14441294960249149,2.534393935132652,1.085314604290465,-1.005414393292386,-1.053592111071168,1.1268435085723476,0.15380286431879417
3,477
ATP synthase
6
22
2.932879
0.003358
O75964,Q15904,Q93050,P00846,P56385,Q9Y487
Functions
Panther Protein class
panther_protein_class
32,270,17,20,283,123
2464,1283,32,20,655,858,2898,339,1569,942,2048,2173,845,283,1438,270,1410,17,533,1279,123,1311
-0.5094115023895259,0.09961191055323138,3.141943931656318,3.333065755789585,0.6724902109286491,0.4304652245976121,-0.7499438782500567,1.261829326445677,-0.06768439960582033,0.34616397120861425,-0.3025146589063486,-0.3634680295925095,0.4471003091088909,1.4549503603205254,0.007563093228499072,1.4798985250540877,0.02614916726068394,3.373845322764859,0.8552381999638872,0.11776071457762759,2.101842136086416,0.09961191055323138
3,477
Corneal opacity
25
64
2.932287
0.003365
O43505,Q5H8A4,Q9Y4P3,O95202,Q9H9S5,Q9Y5Z9,Q16625,P06280,P10619,Q9NX14,Q6NUK1,P16278,P35670,O96028,P53701,O75844,Q06136,Q13510,P40855,Q9NVI7,P04062,P56589,O75381,P51648,O75845
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
384,512,525,139,402,148,411,281,160,552,429,68,326,331,204,89,219,100,357,368,106,238,362,118,375
3464,2195,2416,384,2658,2163,2131,3367,362,1065,89,375,3045,139,1788,331,1251,106,717,281,640,3009,160,68,1876,2201,1191,2096,326,357,2246,118,2248,204,1393,238,2674,2340,1093,219,1230,3163,100,949,2349,1765,411,512,429,3027,3268,2998,2220,565,3310,402,368,552,1988,2495,1468,997,525,148
-2.6779095136615876,-0.3839946459113293,-0.48823524922289674,1.1678883030223781,-0.6169874837196055,-0.3634680295925095,-0.3430464255779581,-1.3808477342331456,1.2084584164574235,0.24244901301698119,2.415445977405476,1.181463958349545,-0.8641224313366287,2.0077854950437413,-0.18334808070797615,1.2882110433921183,0.11776071457762759,2.291773758375661,0.5935621359363286,1.4549503603205254,0.6880742208527362,-0.8410331326310951,1.8558377322438417,2.5877825531853427,-0.2226723202632471,-0.3839946459113293,0.15380286431879417,-0.3227289322669874,1.3013270958737004,1.2218778955284642,-0.4046271871534076,2.142778735840569,-0.4046271871534076,1.6731403254770958,0.02614916726068394,1.60196449660163,-0.6169874837196055,-0.4462137510231218,0.22488395017924478,1.649582259474987,0.13582414108741372,-0.9815313424120201,2.358972488129669,0.34616397120861425,-0.4462137510231218,-0.16383228267364128,1.1130548036372934,0.8848196367866663,1.071362388503744,-0.8410331326310951,-1.1269078629663312,-0.8180718103176833,-0.3839946459113293,0.795338037054623,-1.2015158504193209,1.1405784257109197,1.2084584164574235,0.8254121420894225,-0.262392262257652,-0.5094115023895259,0.007563093228499072,0.31190736282418247,0.870059284479323,1.9650890031069095
3,477
Macromolecule transmembrane transporter activity
9
13
2.93088
0.00338
O60830,Q99595,Q9NS69,Q07820,O14925,O96008,Q15388,Q9UGP8,P49755
Functions
GO Molecular function
msigdb_gomf
0,1,2,451,173,527,463,637,441
873,173,0,1633,527,441,630,1170,451,463,1,2,637
0.4137558381966468,1.7771424058672443,4.258503091616609,-0.10586048643661662,0.8552381999638872,1.0432918958486117,0.7035921494358485,0.17169755104451068,1.029172877098212,0.9864762058893607,4.258503091616609,4.030663110153479,0.7035921494358485
3,477
Hydrogen ion transport
6
21
2.927479
0.003417
O75964,Q15904,Q93050,P00846,P56385,Q9Y487
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
32,270,17,20,283,123
2464,1283,32,20,655,858,2898,339,1569,942,843,2048,2173,845,283,1438,270,17,1279,123,1311
-0.5094115023895259,0.09961191055323138,3.141943931656318,3.333065755789585,0.6724902109286491,0.4304652245976121,-0.7499438782500567,1.261829326445677,-0.06768439960582033,0.34616397120861425,0.4471003091088909,-0.3025146589063486,-0.3634680295925095,0.4471003091088909,1.4549503603205254,0.007563093228499072,1.4798985250540877,3.373845322764859,0.11776071457762759,2.101842136086416,0.09961191055323138
3,477
Membrane lipid catabolic process
7
12
2.920146
0.003499
Q13510,O95470,P04062,P06865,P17900,P50897,P06280
Processes and pathways
GO Biological process
msigdb_gobp
100,105,106,235,408,26,281
105,106,717,281,235,1287,408,26,1960,100,471,1987
2.3014619358985096,2.291773758375661,0.5935621359363286,1.4549503603205254,1.613932265149701,0.09961191055323138,1.1130548036372934,3.2355640449184544,-0.262392262257652,2.358972488129669,0.972129499196718,-0.262392262257652
3,477
Outer mitochondrial membrane protein complex
12
16
2.917048
0.003534
Q13505,Q9NS69,Q8N4H5,Q9Y512,Q9BUR5,Q6UXV4,O96008,Q15388,Q9NX63,Q16891,Q8IWA4,Q5XKP0
Localization
GO Cellular component
msigdb_gocc
353,2,34,650,421,299,527,463,383,341,738,287
749,1633,527,2099,353,463,341,287,299,738,34,421,2,1211,383,650
0.5615113239535318,-0.10586048643661662,0.8552381999638872,-0.3227289322669874,1.2352459870262076,0.9864762058893607,1.261829326445677,1.442407617676143,1.3917722506837715,0.5775714858809151,3.127266464039714,1.085314604290465,4.030663110153479,0.15380286431879417,1.181463958349545,0.6880742208527362
3,477
Liposaccharide metabolic process
11
18
2.910199
0.003612
Q5H8A4,P16278,P04062,P06865,Q8NBX0,Q16739,P04066,P17900,Q99805,O43292,P06280
Processes and pathways
GO Biological process
msigdb_gobp
512,68,106,235,269,83,717,408,223,654,281
654,1220,106,717,281,235,1287,68,408,1960,879,83,512,269,782,1551,1379,223
0.6724902109286491,0.13582414108741372,2.291773758375661,0.5935621359363286,1.4549503603205254,1.613932265149701,0.09961191055323138,2.5877825531853427,1.1130548036372934,-0.262392262257652,0.4137558381966468,2.461737501871504,0.8848196367866663,1.4923045082617816,0.5291804175825732,-0.048735570818035576,0.04464637679634543,1.649582259474987
3,477
Mitochondrial calcium ion transport
10
16
2.904519
0.003678
Q8WWC4,Q99623,Q8IYU8,O95202,P45880,Q9BPX6,P21796,Q9Y277,Q8NE86,Q10713
Processes and pathways
Reactome Pathways
msigdb_reactome
323,288,136,139,12,244,23,250,547,416
1996,139,23,600,12,416,136,547,323,1806,1038,288,244,956,250,812
-0.2824027254226025,2.0077854950437413,3.284733395150704,0.7344316400083396,3.5880722275384778,1.0992119552130728,2.0289249011183346,0.8254121420894225,1.3143936999272097,-0.18334808070797615,0.27733733002235417,1.442407617676143,1.577900780996791,0.34616397120861425,1.5536644399111408,0.4965652697383779
3,477
Abnormality of corneal stroma
7
15
2.900889
0.003721
P10619,O43505,Q13510,P16278,P04062,Q9Y5Z9,O75845
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
160,384,100,68,106,148,375
384,375,106,160,68,1876,2201,1191,1393,100,411,3027,2220,1468,148
1.1678883030223781,1.181463958349545,2.291773758375661,1.8558377322438417,2.5877825531853427,-0.2226723202632471,-0.3839946459113293,0.15380286431879417,0.02614916726068394,2.358972488129669,1.1130548036372934,-0.8410331326310951,-0.3839946459113293,0.007563093228499072,1.9650890031069095
3,477
Abnormal tissue metabolite concentration
7
16
2.895954
0.00378
P40855,P06865,P56589,O75381,Q9NZJ7,P07602,P06280
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
357,235,238,362,406,24,281
758,362,1788,281,235,24,1287,1875,408,357,1226,238,892,1268,406,1938
0.5453811397505782,1.2084584164574235,-0.18334808070797615,1.4549503603205254,1.613932265149701,3.2426404073511974,0.09961191055323138,-0.2226723202632471,1.1130548036372934,1.2218778955284642,0.13582414108741372,1.60196449660163,0.3969715892812894,0.11776071457762759,1.1268435085723476,-0.24248241020736983
3,477
Glycoprotein biosynthetic process
24
57
2.892757
0.003819
O43505,Q96L58,Q9Y673,Q8N6G5,Q8TCJ2,O15118,Q9H9S5,Q13724,Q96AA3,O14734,P46977,Q9BT22,Q10472,Q9P2E5,Q7LGA3,Q2TAA5,Q9NQX7,Q99805,Q9H4A6,Q8NCH0,O60502,Q8WVQ1,Q92542,P04843
Processes and pathways
GO Biological process
msigdb_gobp
384,256,786,137,660,142,402,795,662,535,415,163,305,716,322,577,334,223,350,95,103,241,379,762
2272,535,142,1708,384,103,1746,2945,1220,2659,2619,2240,762,1046,1682,2507,1475,415,1574,1958,1229,2054,818,1401,1758,305,795,1440,2762,577,986,2302,2638,322,1651,2305,137,95,660,241,379,662,1035,256,223,163,1014,993,350,402,334,1138,2732,716,2410,1865,786
-0.42536657713018505,0.8403559612194028,1.9865073756421463,-0.14441294960249149,1.1678883030223781,2.320749325149068,-0.16383228267364128,-0.7952372743225334,0.13582414108741372,-0.6169874837196055,-0.595242946157797,-0.4046271871534076,0.5453811397505782,0.25993326491209245,-0.12508928118991622,-0.5306993975719276,-0.011112566654353354,1.0992119552130728,-0.06768439960582033,-0.262392262257652,0.13582414108741372,-0.3025146589063486,0.4801497856111335,0.02614916726068394,-0.16383228267364128,1.3661718533156093,0.5129086364034002,0.007563093228499072,-0.6608278481110601,0.7802068776839349,0.31190736282418247,-0.42536657713018505,-0.595242946157797,1.3143936999272097,-0.10586048643661662,-0.42536657713018505,2.018372441939004,2.396734762422103,0.6724902109286491,1.5899540873792353,1.181463958349545,0.6724902109286491,0.27733733002235417,1.5292533775321773,1.649582259474987,1.8447097839425666,0.29466182574769184,0.31190736282418247,1.2485630214820864,1.1405784257109197,1.2882110433921183,0.2072374453876056,-0.6388487645543015,0.6094837793071348,-0.4671696555646836,-0.2029611534569842,0.5291804175825732
3,477
Sphingolipid metabolism
8
11
2.884647
0.003919
Q13510,O95470,P04062,Q16739,Q9NZ01,P17900,P07602,Q06136
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
100,105,106,83,311,408,24,219
542,1018,105,106,24,408,219,100,83,2640,311
0.8254121420894225,0.27733733002235417,2.3014619358985096,2.291773758375661,3.2426404073511974,1.1130548036372934,1.649582259474987,2.358972488129669,2.461737501871504,-0.595242946157797,1.3403798125660904
3,477
Protein transmembrane transporter activity
8
12
2.882363
0.003947
O60830,Q99595,Q9NS69,Q07820,O14925,O96008,Q15388,P49755
Functions
GO Molecular function
msigdb_gomf
0,1,2,451,173,527,463,441
873,173,0,1633,527,441,1170,451,463,1,2,637
0.4137558381966468,1.7771424058672443,4.258503091616609,-0.10586048643661662,0.8552381999638872,1.0432918958486117,0.17169755104451068,1.029172877098212,0.9864762058893607,4.258503091616609,4.030663110153479,0.7035921494358485
3,477
Glycosphingolipid metabolic process
6
10
2.872095
0.004078
P16278,P04062,P06865,Q16739,Q99805,P06280
Processes and pathways
GO Biological process
msigdb_gobp
68,106,235,83,223,281
106,281,235,1287,68,408,1960,879,83,223
2.291773758375661,1.4549503603205254,1.613932265149701,0.09961191055323138,2.5877825531853427,1.1130548036372934,-0.262392262257652,0.4137558381966468,2.461737501871504,1.649582259474987
3,477
Nucleobase containing compound transmembrane transporter activity
10
16
2.863902
0.004185
P12236,P41440,Q8TB61,Q9BSK2,P12235,Q6NUK1,Q9H2D1,P51991,O00400,Q9HC21
Functions
GO Molecular function
msigdb_gomf
418,388,132,297,457,429,143,630,312,414
1389,312,803,1282,627,457,418,388,630,429,2358,132,1520,297,143,414
0.02614916726068394,1.3274111687020549,0.4965652697383779,0.09961191055323138,0.7035921494358485,1.0149975096355603,1.085314604290465,1.1678883030223781,0.7035921494358485,1.071362388503744,-0.4462137510231218,2.0603772329418755,-0.02987854200342981,1.4045013303564935,1.9865073756421463,1.1130548036372934
3,477
EF-hand domain [IPR002048]
18
47
2.861955
0.00421
Q9BRK5,Q8IXI1,P41208,Q8IYU8,Q02818,P80303,O95202,O43852,Q9UBV8,Q6NUK1,Q9NWM8,Q9UJS0,Q15293,O95302,Q9Y680,Q9BPX6,Q14257,Q8NF37
Sequence
InterPro Domain
interpro_domain
261,486,196,136,40,10,139,455,335,429,464,465,370,179,53,244,151,284
1248,455,2659,593,139,179,1826,656,1789,3431,1947,3142,1681,2622,3440,196,3358,644,3050,10,40,1093,1723,1363,151,2678,370,1484,429,486,1077,136,284,799,1657,501,244,261,953,1775,464,2408,2227,335,465,2574,53
0.11776071457762759,1.0149975096355603,-0.6169874837196055,0.7497541290280656,2.0077854950437413,1.76574583954448,-0.2029611534569842,0.6724902109286491,-0.18334808070797615,-1.7634372543568286,-0.262392262257652,-0.9577837491650766,-0.12508928118991622,-0.595242946157797,-1.8499329075198376,1.6965338049214893,-1.3547654978043482,0.6880742208527362,-0.8641224313366287,3.722151271614355,3.014751081880716,0.22488395017924478,-0.14441294960249149,0.04464637679634543,1.9326950418116124,-0.6169874837196055,1.1949872162647377,-0.011112566654353354,1.071362388503744,0.9432620224784491,0.24244901301698119,2.0289249011183346,1.4549503603205254,0.5129086364034002,-0.10586048643661662,0.9141598124921,1.577900780996791,1.5169816611056757,0.34616397120861425,-0.16383228267364128,0.9864762058893607,-0.4671696555646836,-0.3839946459113293,1.2882110433921183,0.9864762058893607,-0.5520999295887415,2.792436632211358
3,477
Secretory granule membrane
21
71
2.855439
0.004298
O75787,Q4KMQ2,O15121,P30519,Q93050,Q9NZJ7,O00264,P35613,Q8NF37,P07602,P42785,Q969Q5,P49755,P01889,Q9NQX7,Q15363,Q07065,P10321,Q92542,P10253,O15260
Localization
GO Cellular component
msigdb_gocc
386,389,133,8,17,406,273,409,284,24,35,314,441,446,334,81,233,364,379,121,374
3430,273,133,1314,374,803,3085,1747,3088,1786,2742,386,3156,639,446,24,121,364,482,788,3276,2539,2137,774,8,2622,2284,409,1475,35,2858,441,1916,2247,1022,3124,1538,966,1794,2010,3455,2141,3294,1227,3451,233,750,2177,2343,1440,910,81,389,3360,1096,284,1892,379,17,314,1299,754,1854,1014,1303,334,406,1492,1016,1311,1867
-1.7349758005516078,1.4674472355220745,2.0394430613633685,0.08137704720652839,1.181463958349545,0.4965652697383779,-0.9106897973314252,-0.16383228267364128,-0.9106897973314252,-0.18334808070797615,-0.6608278481110601,1.1678883030223781,-0.9815313424120201,0.6880742208527362,1.029172877098212,3.2426404073511974,2.1121253696676408,1.2084584164574235,0.9432620224784491,0.5129086364034002,-1.1516317262366567,-0.5520999295887415,-0.3430464255779581,0.5291804175825732,3.780969419215487,-0.595242946157797,-0.42536657713018505,1.1130548036372934,-0.011112566654353354,3.1125140490108847,-0.7274827145107601,1.0432918958486117,-0.24248241020736983,-0.4046271871534076,0.27733733002235417,-0.9341703246969754,-0.048735570818035576,0.3290745454164685,-0.18334808070797615,-0.2824027254226025,-2.2771543247779946,-0.3430464255779581,-1.176500576169906,0.13582414108741372,-2.11991428298489,1.6258576473578923,0.5615113239535318,-0.3634680295925095,-0.4462137510231218,0.007563093228499072,0.3801119112602281,2.470913514380328,1.1678883030223781,-1.3547654978043482,0.22488395017924478,1.4549503603205254,-0.2226723202632471,1.181463958349545,3.373845322764859,1.3274111687020549,0.09961191055323138,0.5615113239535318,-0.2029611534569842,0.29466182574769184,0.09961191055323138,1.2882110433921183,1.1268435085723476,-0.011112566654353354,0.29466182574769184,0.09961191055323138,-0.2029611534569842
3,477
Steroid biosynthesis
10
23
2.84454
0.004448
P48449,Q15125,Q15800,P04035,P37268,O76062,Q15392,Q16850,Q14739,Q53GQ0
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
217,167,141,210,117,274,126,153,187,253
375,274,1534,210,815,117,217,2796,2755,3380,187,167,3200,126,883,141,153,253,913,2567,1209,1988,1016
1.181463958349545,1.4674472355220745,-0.048735570818035576,1.6613819875037117,0.4801497856111335,2.142778735840569,1.649582259474987,-0.6829258074091615,-0.6608278481110601,-1.4070886524662474,1.731319631584345,1.8110987672570336,-1.0294342081393086,2.0811764381859885,0.4137558381966468,2.0077854950437413,1.9218252181935185,1.541480881266963,0.3801119112602281,-0.5520999295887415,0.15380286431879417,-0.262392262257652,0.29466182574769184
3,477
Abnormal biliary tract morphology
8
24
2.835241
0.004579
P09601,P04062,Q14108,Q9NSD9,Q9NZJ7,P07602,Q14739,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
41,106,14,115,406,24,187,287
758,1251,106,24,41,2468,1875,3357,2002,2207,1226,416,1403,14,187,287,2220,3224,1491,115,406,638,1938,2194
0.5453811397505782,0.11776071457762759,2.291773758375661,3.2426404073511974,2.9762603054079118,-0.5094115023895259,-0.2226723202632471,-1.3547654978043482,-0.2824027254226025,-0.3839946459113293,0.13582414108741372,1.0992119552130728,0.02614916726068394,3.4206854913567066,1.731319631584345,1.442407617676143,-0.3839946459113293,-1.053592111071168,-0.011112566654353354,2.16305244697371,1.1268435085723476,0.7035921494358485,-0.24248241020736983,-0.3634680295925095
3,477
Hexosyltransferase activity
14
36
2.830399
0.004649
O43505,Q96L58,P46977,Q9BT22,Q2TAA5,Q13126,Q8N6G5,Q8TCJ2,P04062,P06865,Q10472,Q16739,P04843,Q9P2E5
Functions
GO Molecular function
msigdb_gomf
384,256,415,163,577,260,137,660,106,235,305,83,762,716
2272,1708,384,1746,1220,2659,106,762,1046,1748,235,1287,2280,1713,2245,2139,415,1229,1401,1758,305,260,83,577,2302,2638,1651,137,1513,660,256,163,993,2732,716,786
-0.42536657713018505,-0.14441294960249149,1.1678883030223781,-0.16383228267364128,0.13582414108741372,-0.6169874837196055,2.291773758375661,0.5453811397505782,0.25993326491209245,-0.16383228267364128,1.613932265149701,0.09961191055323138,-0.42536657713018505,-0.14441294960249149,-0.4046271871534076,-0.3430464255779581,1.0992119552130728,0.13582414108741372,0.02614916726068394,-0.16383228267364128,1.3661718533156093,1.5169816611056757,2.461737501871504,0.7802068776839349,-0.42536657713018505,-0.595242946157797,-0.10586048643661662,2.018372441939004,-0.02987854200342981,0.6724902109286491,1.5292533775321773,1.8447097839425666,0.31190736282418247,-0.6388487645543015,0.6094837793071348,0.5291804175825732
3,477
Arteriosclerosis
7
18
2.828942
0.00467
P38435,Q13510,P16278,P38571,O15118,O75844,O75845
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
162,100,68,232,142,89,375
142,2921,89,375,1251,68,1876,2201,2668,1191,162,232,420,100,1364,2020,2220,1268
1.9865073756421463,-0.7725283500753476,2.415445977405476,1.181463958349545,0.11776071457762759,2.5877825531853427,-0.2226723202632471,-0.3839946459113293,-0.6169874837196055,0.15380286431879417,1.8447097839425666,1.6258576473578923,1.085314604290465,2.358972488129669,0.04464637679634543,-0.2824027254226025,-0.3839946459113293,0.11776071457762759
3,477
Peroxisomes
6
16
2.827621
0.00469
O00116,P40855,P56589,O75381,Q9BY49,O15254
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
225,357,238,362,277,251
225,251,1282,362,1472,2661,1333,1048,357,1226,238,403,892,1344,277,1526
1.6377408954325872,1.541480881266963,0.09961191055323138,1.2084584164574235,-0.011112566654353354,-0.6169874837196055,0.0630554350483885,0.25993326491209245,1.2218778955284642,0.13582414108741372,1.60196449660163,1.1268435085723476,0.3969715892812894,0.0630554350483885,1.4674472355220745,-0.02987854200342981
3,477
Intrinsic component of golgi membrane
9
13
2.826115
0.004712
O43505,Q8TB61,Q9Y282,Q8N6G5,Q969X5,Q9Y5Z9,P98194,O95070,Q6ZRP7
Localization
GO Cellular component
msigdb_gocc
384,132,9,137,531,148,186,216,710
1389,748,384,216,186,1758,710,137,132,531,9,1312,148
0.02614916726068394,0.5615113239535318,1.1678883030223781,1.649582259474987,1.731319631584345,-0.16383228267364128,0.6094837793071348,2.018372441939004,2.0603772329418755,0.8552381999638872,3.7751451557105193,0.09961191055323138,1.9650890031069095
3,477
Lipid droplet
7
30
2.821731
0.004777
P48449,Q07065,O43760,Q8NBX0,Q99720,Q9H6V9,Q01105
Localization
GO Cellular component
msigdb_gocc
217,233,107,269,16,18,252
2578,107,1565,1630,1222,1534,3007,1567,217,1916,2247,585,2862,252,233,883,752,913,269,284,2309,1268,1100,495,16,1775,18,1303,2458,852
-0.5736141057694272,2.2820557203662677,-0.06768439960582033,-0.10586048643661662,0.13582414108741372,-0.048735570818035576,-0.8410331326310951,-0.06768439960582033,1.649582259474987,-0.24248241020736983,-0.4046271871534076,0.7650123908871262,-0.7274827145107601,1.541480881266963,1.6258576473578923,0.4137558381966468,0.5615113239535318,0.3801119112602281,1.4923045082617816,1.4549503603205254,-0.42536657713018505,0.11776071457762759,0.22488395017924478,0.9287404597149378,3.387308237114521,-0.16383228267364128,3.367089603944026,0.09961191055323138,-0.48823524922289674,0.4471003091088909
3,477
Progressive neurologic deterioration
8
20
2.811582
0.00493
P16278,P04062,P54802,Q9NPL8,Q9NZJ7,P07602,Q5XKP0,P21912
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
68,106,140,371,406,24,287,125
758,106,24,1287,1875,68,1089,125,2667,2003,140,1393,2862,416,3074,287,2301,2158,371,406
0.5453811397505782,2.291773758375661,3.2426404073511974,0.09961191055323138,-0.2226723202632471,2.5877825531853427,0.22488395017924478,2.0811764381859885,-0.6169874837196055,-0.2824027254226025,2.0077854950437413,0.02614916726068394,-0.7274827145107601,1.0992119552130728,-0.8873409122764672,1.442407617676143,-0.42536657713018505,-0.3430464255779581,1.1949872162647377,1.1268435085723476
3,477
Optic disc pallor
22
51
2.810459
0.004947
O75306,Q96L58,O96000,Q9H6K4,Q9H0B6,O43676,P00846,Q10713,Q9Y375,Q9NX14,Q9BUK6,Q9UG56,O60313,Q86Y39,P51798,Q8N183,Q9H061,Q96CU9,P04439,O95831,Q9NPL8,Q9Y6M9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,256,510,138,400,19,20,416,289,552,292,300,308,193,586,587,74,77,468,227,371,116
902,3464,1086,2040,19,1218,308,1995,128,1498,1996,1355,2537,1284,227,510,20,903,468,2504,1948,1828,3393,3249,586,3448,3370,416,1483,2720,193,865,587,894,1805,2359,77,256,607,2999,292,74,400,138,371,552,1108,300,289,812,116
0.3801119112602281,-2.6779095136615876,0.22488395017924478,-0.3025146589063486,3.3399034479628043,0.13582414108741372,1.3403798125660904,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,-0.2824027254226025,0.04464637679634543,-0.5520999295887415,0.09961191055323138,1.6377408954325872,0.8848196367866663,3.333065755789585,0.3801119112602281,0.972129499196718,-0.5306993975719276,-0.262392262257652,-0.2029611534569842,-1.4867799433989366,-1.1023275684761824,0.7650123908871262,-2.0281123101002554,-1.3808477342331456,1.0992119552130728,-0.011112566654353354,-0.6388487645543015,1.7081694282043638,0.4304652245976121,0.7650123908871262,0.3969715892812894,-0.18334808070797615,-0.4462137510231218,2.525404913107488,1.5292533775321773,0.7344316400083396,-0.8180718103176833,1.4171833906612892,2.534393935132652,1.1405784257109197,2.018372441939004,1.1949872162647377,0.8254121420894225,0.22488395017924478,1.3917722506837715,1.442407617676143,0.4965652697383779,2.16305244697371
3,477
Transmembrane transport
100
228
2.809073
0.004968
O60830,Q99595,Q9NS69,Q8NE01,Q9BQT8,P45880,O96008,P46934,P00846,P21796,Q3ZCQ8,Q15041,Q8NE86,Q9C0H2,O75964,Q13423,Q9UHG3,Q9UDW1,Q9UBX3,Q8N4V1,Q6P4A7,Q99442,Q15629,Q8WTV0,P51798,O75746,O75844,P23786,Q9H2V7,O75298,Q9HD20,P04062,P51790,Q8NEW0,Q9UGP8,Q9NRK6,Q70HW3,P20674,P05141,O75027,Q8TB61,P05067,P31930,Q8IYU8,O95202,Q9H9B4,Q9H2D1,P0DP25,Q5T3U5,P13073,P38435,Q15043,O14925,P78417,P98194,Q9Y5Y0,P08183,O43772,O95831,Q9H2J7,P16615,Q9BPX6,Q9Y619,Q8IXU6,Q9Y277,P00403,P56385,Q99623,P05023,Q9BSK2,P52789,P30825,O00400,Q8WWC4,P35670,P24539,O14548,O75381,Q96NB2,P41440,Q4KMQ2,Q13586,P50416,Q16625,Q9HC21,P12236,Q6NUK1,P31751,O60831,Q9UKG1,P49755,P20020,Q07820,P12235,O43615,Q15388,Q9UJS0,P53985,Q14728,Q99523
Processes and pathways
GO Biological process
msigdb_gobp
0,1,2,513,522,12,527,529,20,23,537,536,547,31,32,36,38,50,54,56,67,588,69,71,586,593,89,93,97,597,101,106,108,114,637,634,122,628,627,129,132,134,643,136,139,667,143,656,155,159,162,164,173,174,186,189,211,215,227,229,231,244,247,249,250,258,283,288,291,297,293,307,312,323,326,339,351,362,380,388,389,395,394,411,414,418,429,426,425,444,441,447,451,457,454,463,465,489,491,496
1389,1247,873,2979,312,920,351,1942,173,803,454,1248,215,1282,2461,3085,0,425,129,3087,1995,597,2464,362,1996,593,89,813,1283,32,1633,139,1431,227,527,258,20,3418,106,3092,291,134,627,1143,1536,655,1567,1826,1224,961,3275,211,922,830,2199,656,1316,2200,1067,1164,457,418,159,1874,231,3191,1681,447,628,858,2898,3369,23,877,93,339,1569,3377,2138,1048,3182,2622,307,1117,426,643,1436,1049,326,3235,942,843,162,2048,3434,388,3212,12,529,2004,2173,441,2587,394,1641,108,586,293,1599,489,2050,1023,790,845,283,1917,1955,1438,1170,1004,3263,174,186,1050,2594,3451,943,3399,1602,3341,1192,879,451,3071,2516,36,719,3390,395,2711,491,1689,536,164,2056,463,69,863,1726,411,1690,537,389,155,429,1582,67,2720,3202,1235,122,1076,2358,1928,249,136,2685,56,1202,513,547,114,132,2561,71,323,1376,722,2562,380,1976,588,3362,496,1,288,742,1520,2189,244,522,297,1554,916,3327,1040,31,1014,143,229,97,2649,667,917,414,101,1462,634,2,995,54,50,637,2410,38,1279,465,956,444,701,250,957,1817,2576,812,189,247,3347
0.02614916726068394,0.11776071457762759,0.4137558381966468,-0.8180718103176833,1.3274111687020549,0.363176231493417,1.2352459870262076,-0.262392262257652,1.7771424058672443,0.4965652697383779,1.0149975096355603,0.11776071457762759,1.649582259474987,0.09961191055323138,-0.5094115023895259,-0.9106897973314252,4.258503091616609,1.071362388503744,2.0603772329418755,-0.9106897973314252,-0.2824027254226025,0.7344316400083396,-0.5094115023895259,1.2084584164574235,-0.2824027254226025,0.7497541290280656,2.415445977405476,0.4801497856111335,0.09961191055323138,3.141943931656318,-0.10586048643661662,2.0077854950437413,0.007563093228499072,1.6377408954325872,0.8552381999638872,1.5169816611056757,3.333065755789585,-1.6785966185631933,2.291773758375661,-0.9106897973314252,1.4171833906612892,2.0394430613633685,0.7035921494358485,0.18950886067998413,-0.048735570818035576,0.6724902109286491,-0.06768439960582033,-0.2029611534569842,0.13582414108741372,0.3290745454164685,-1.1516317262366567,1.6613819875037117,0.363176231493417,0.4636616464692855,-0.3839946459113293,0.6724902109286491,0.08137704720652839,-0.3839946459113293,0.24244901301698119,0.17169755104451068,1.0149975096355603,1.085314604290465,1.866928176818198,-0.2226723202632471,1.6258576473578923,-1.0294342081393086,-0.12508928118991622,1.029172877098212,0.7035921494358485,0.4304652245976121,-0.7499438782500567,-1.3808477342331456,3.284733395150704,0.4137558381966468,2.396734762422103,1.261829326445677,-0.06768439960582033,-1.4070886524662474,-0.3430464255779581,0.25993326491209245,-1.005414393292386,-0.595242946157797,1.3532999391374014,0.2072374453876056,1.071362388503744,0.6880742208527362,0.007563093228499072,0.25993326491209245,1.3013270958737004,-1.077889444304914,0.34616397120861425,0.4471003091088909,1.8447097839425666,-0.3025146589063486,-1.7920825787050783,1.1678883030223781,-1.053592111071168,3.5880722275384778,0.8552381999638872,-0.2824027254226025,-0.3634680295925095,1.0432918958486117,-0.5736141057694272,1.1542599074685331,-0.10586048643661662,2.2625294404559577,0.7650123908871262,1.4045013303564935,-0.08672578350961495,0.9287404597149378,-0.3025146589063486,0.27733733002235417,0.5129086364034002,0.4471003091088909,1.4549503603205254,-0.24248241020736983,-0.262392262257652,0.007563093228499072,0.17169755104451068,0.29466182574769184,-1.1269078629663312,1.7771424058672443,1.731319631584345,0.25993326491209245,-0.5736141057694272,-2.11991428298489,0.34616397120861425,-1.5136721546532035,-0.08672578350961495,-1.3030706558113276,0.15380286431879417,0.4137558381966468,1.029172877098212,-0.8873409122764672,-0.5306993975719276,3.0902434831082837,0.5935621359363286,-1.4600530886095953,1.1542599074685331,-0.6388487645543015,0.9287404597149378,-0.12508928118991622,0.8403559612194028,1.8335441178353415,-0.3025146589063486,0.9864762058893607,2.5877825531853427,0.4304652245976121,-0.14441294960249149,1.1130548036372934,-0.12508928118991622,0.8403559612194028,1.1678883030223781,1.8999766035038268,1.071362388503744,-0.06768439960582033,2.6402555038244877,-0.6388487645543015,-1.0294342081393086,0.13582414108741372,2.101842136086416,0.24244901301698119,-0.4462137510231218,-0.24248241020736983,1.5536644399111408,2.0289249011183346,-0.6169874837196055,2.7676008494517013,0.15380286431879417,0.8848196367866663,0.8254121420894225,2.16305244697371,2.0603772329418755,-0.5520999295887415,2.5700894098740656,1.3143936999272097,0.04464637679634543,0.5935621359363286,-0.5520999295887415,1.181463958349545,-0.262392262257652,0.7650123908871262,-1.3547654978043482,0.9287404597149378,4.258503091616609,1.442407617676143,0.5775714858809151,-0.02987854200342981,-0.3634680295925095,1.577900780996791,0.870059284479323,1.4045013303564935,-0.048735570818035576,0.3801119112602281,-1.25199152348041,0.27733733002235417,3.1783138805528677,0.29466182574769184,1.9865073756421463,1.6377408954325872,2.3779106499781055,-0.595242946157797,0.6724902109286491,0.3801119112602281,1.1130548036372934,2.358972488129669,0.007563093228499072,0.7035921494358485,4.030663110153479,0.31190736282418247,2.784180874695723,2.825233750109732,0.7035921494358485,-0.4671696555646836,3.030006778420197,0.11776071457762759,0.9864762058893607,0.34616397120861425,1.0432918958486117,0.6253369160329553,1.5536644399111408,0.34616397120861425,-0.18334808070797615,-0.5520999295887415,0.4965652697383779,1.731319631584345,1.5658043187937936,-1.3030706558113276
3,477
Cation transmembrane transport
38
124
2.808644
0.004975
O75027,Q4KMQ2,P05067,P00403,Q8IYU8,Q13586,O95202,P00846,P21796,P56385,Q9HC21,P13073,O75964,Q99623,P05023,Q13423,Q15043,P78417,Q9UDW1,P30825,Q8N4V1,O00400,P98194,P20020,Q8WWC4,P35670,P24539,O43772,O14548,Q9H2J7,Q9HD20,P16615,P51790,Q8NEW0,Q9BPX6,Q9Y619,Q96NB2,Q70HW3
Processes and pathways
GO Biological process
msigdb_gobp
129,389,134,258,136,395,139,20,23,283,414,159,32,288,291,36,164,174,50,307,56,312,186,447,323,326,339,215,351,229,101,231,108,114,244,247,380,122
312,920,351,1942,1248,215,3085,129,1995,2464,1996,1283,32,139,258,20,3418,291,134,627,1143,655,1567,1826,961,3275,922,830,656,1316,1164,457,159,1874,231,3191,1681,447,628,858,2898,3369,23,877,339,1569,3377,2138,3182,2622,307,643,326,3235,942,843,2048,3212,529,2004,2173,1641,108,2050,1023,790,845,283,1438,1170,1004,3263,174,186,1050,2594,1602,1192,879,3071,2516,36,3390,395,2711,164,2056,863,389,2720,3202,122,1928,136,2685,56,547,114,323,1376,722,2562,380,1976,3362,288,2189,244,916,1014,229,2649,667,414,101,995,50,2410,1279,956,701,1817,812,247
1.3274111687020549,0.363176231493417,1.2352459870262076,-0.262392262257652,0.11776071457762759,1.649582259474987,-0.9106897973314252,2.0603772329418755,-0.2824027254226025,-0.5094115023895259,-0.2824027254226025,0.09961191055323138,3.141943931656318,2.0077854950437413,1.5169816611056757,3.333065755789585,-1.6785966185631933,1.4171833906612892,2.0394430613633685,0.7035921494358485,0.18950886067998413,0.6724902109286491,-0.06768439960582033,-0.2029611534569842,0.3290745454164685,-1.1516317262366567,0.363176231493417,0.4636616464692855,0.6724902109286491,0.08137704720652839,0.17169755104451068,1.0149975096355603,1.866928176818198,-0.2226723202632471,1.6258576473578923,-1.0294342081393086,-0.12508928118991622,1.029172877098212,0.7035921494358485,0.4304652245976121,-0.7499438782500567,-1.3808477342331456,3.284733395150704,0.4137558381966468,1.261829326445677,-0.06768439960582033,-1.4070886524662474,-0.3430464255779581,-1.005414393292386,-0.595242946157797,1.3532999391374014,0.6880742208527362,1.3013270958737004,-1.077889444304914,0.34616397120861425,0.4471003091088909,-0.3025146589063486,-1.053592111071168,0.8552381999638872,-0.2824027254226025,-0.3634680295925095,-0.10586048643661662,2.2625294404559577,-0.3025146589063486,0.27733733002235417,0.5129086364034002,0.4471003091088909,1.4549503603205254,0.007563093228499072,0.17169755104451068,0.29466182574769184,-1.1269078629663312,1.7771424058672443,1.731319631584345,0.25993326491209245,-0.5736141057694272,-0.08672578350961495,0.15380286431879417,0.4137558381966468,-0.8873409122764672,-0.5306993975719276,3.0902434831082837,-1.4600530886095953,1.1542599074685331,-0.6388487645543015,1.8335441178353415,-0.3025146589063486,0.4304652245976121,1.1678883030223781,-0.6388487645543015,-1.0294342081393086,2.101842136086416,-0.24248241020736983,2.0289249011183346,-0.6169874837196055,2.7676008494517013,0.8254121420894225,2.16305244697371,1.3143936999272097,0.04464637679634543,0.5935621359363286,-0.5520999295887415,1.181463958349545,-0.262392262257652,-1.3547654978043482,1.442407617676143,-0.3634680295925095,1.577900780996791,0.3801119112602281,0.29466182574769184,1.6377408954325872,-0.595242946157797,0.6724902109286491,1.1130548036372934,2.358972488129669,0.31190736282418247,2.825233750109732,-0.4671696555646836,0.11776071457762759,0.34616397120861425,0.6253369160329553,-0.18334808070797615,0.4965652697383779,1.5658043187937936
3,477
Fad binding
6
11
2.807018
0.005
O95831,O00116,Q8NB78,Q14534,O15254,Q15392
Functions
GO Molecular function
msigdb_gomf
227,225,268,175,251,126
225,251,227,1534,175,403,126,268,2562,1016,889
1.6377408954325872,1.541480881266963,1.6377408954325872,-0.048735570818035576,1.7771424058672443,1.1268435085723476,2.0811764381859885,1.4923045082617816,-0.5520999295887415,0.29466182574769184,0.4137558381966468
3,477
EF-hand domain pair [IPR011992]
18
52
2.806048
0.005015
Q9BRK5,Q8IXI1,P41208,Q8IYU8,Q02818,P80303,O95202,O43852,Q9UBV8,Q6NUK1,Q9NWM8,Q9UJS0,Q15293,O95302,Q9Y680,Q9BPX6,Q14257,Q8NF37
Sequence
InterPro Superfamily
interpro_homologous_superfamily
261,486,196,136,40,10,139,455,335,429,464,465,370,179,53,244,151,284
1248,455,2659,593,139,179,1826,656,1789,3431,1947,3142,1681,2328,2622,3440,196,3358,644,2004,3050,10,40,1093,1723,1363,151,2678,370,1484,429,1890,486,1077,136,1488,284,799,1657,501,244,261,953,1775,2030,464,2408,2227,335,465,2574,53
0.11776071457762759,1.0149975096355603,-0.6169874837196055,0.7497541290280656,2.0077854950437413,1.76574583954448,-0.2029611534569842,0.6724902109286491,-0.18334808070797615,-1.7634372543568286,-0.262392262257652,-0.9577837491650766,-0.12508928118991622,-0.4462137510231218,-0.595242946157797,-1.8499329075198376,1.6965338049214893,-1.3547654978043482,0.6880742208527362,-0.2824027254226025,-0.8641224313366287,3.722151271614355,3.014751081880716,0.22488395017924478,-0.14441294960249149,0.04464637679634543,1.9326950418116124,-0.6169874837196055,1.1949872162647377,-0.011112566654353354,1.071362388503744,-0.2226723202632471,0.9432620224784491,0.24244901301698119,2.0289249011183346,-0.011112566654353354,1.4549503603205254,0.5129086364034002,-0.10586048643661662,0.9141598124921,1.577900780996791,1.5169816611056757,0.34616397120861425,-0.16383228267364128,-0.2824027254226025,0.9864762058893607,-0.4671696555646836,-0.3839946459113293,1.2882110433921183,0.9864762058893607,-0.5520999295887415,2.792436632211358
3,477
Ion transmembrane transport
66
165
2.804918
0.005033
O75027,Q8TB61,P41440,P05067,P31930,Q8IYU8,P00403,Q4KMQ2,Q9BQT8,P45880,O95202,Q9H9B4,Q9H2D1,P46934,Q13586,P00846,P21796,P0DP25,P56385,Q15041,Q9HC21,Q8NE86,Q9C0H2,O75964,P13073,Q99623,P05023,Q13423,Q15043,Q9UHG3,P12236,P78417,Q9UDW1,P30825,O60831,Q9UBX3,Q8N4V1,O00400,P98194,P20020,Q8WWC4,Q6P4A7,P35670,P51798,P12235,Q9UJS0,O75746,P08183,P24539,O75844,O43772,O14548,Q9H2J7,Q9HD20,P16615,P53985,Q9Y277,Q14728,P51790,Q8NEW0,Q9BPX6,P20674,Q9Y619,Q96NB2,Q70HW3,P05141
Processes and pathways
GO Biological process
msigdb_gobp
129,132,388,134,643,136,258,389,522,12,139,667,143,529,395,20,23,656,283,536,414,547,31,32,159,288,291,36,164,38,418,174,50,307,425,54,56,312,186,447,323,67,326,586,457,465,593,211,339,89,215,351,229,101,231,489,250,491,108,114,244,628,247,380,122,627
2979,312,920,351,1942,803,1248,215,1282,2461,3085,425,129,3087,1995,2464,1996,593,89,813,1283,32,139,1431,258,20,3418,3092,291,134,627,1143,655,1567,1826,961,3275,211,922,830,2199,656,1316,1164,457,418,159,1874,231,3191,1681,447,628,858,2898,3369,23,877,339,1569,3377,2138,3182,2622,307,643,1049,326,3235,942,843,2048,388,3212,12,529,2004,2173,1641,108,586,1599,489,2050,1023,790,845,283,1438,1170,1004,3263,174,186,1050,2594,943,1602,1192,879,3071,2516,36,719,3390,395,2711,491,1689,536,164,2056,863,389,67,2720,3202,122,2358,1928,136,2685,56,1202,547,114,132,323,1376,722,2562,380,1976,3362,288,2189,244,522,1554,916,31,1014,143,229,2649,667,414,101,1462,995,54,50,2410,38,1279,465,956,701,250,957,1817,2576,812,247,3347
-0.8180718103176833,1.3274111687020549,0.363176231493417,1.2352459870262076,-0.262392262257652,0.4965652697383779,0.11776071457762759,1.649582259474987,0.09961191055323138,-0.5094115023895259,-0.9106897973314252,1.071362388503744,2.0603772329418755,-0.9106897973314252,-0.2824027254226025,-0.5094115023895259,-0.2824027254226025,0.7497541290280656,2.415445977405476,0.4801497856111335,0.09961191055323138,3.141943931656318,2.0077854950437413,0.007563093228499072,1.5169816611056757,3.333065755789585,-1.6785966185631933,-0.9106897973314252,1.4171833906612892,2.0394430613633685,0.7035921494358485,0.18950886067998413,0.6724902109286491,-0.06768439960582033,-0.2029611534569842,0.3290745454164685,-1.1516317262366567,1.6613819875037117,0.363176231493417,0.4636616464692855,-0.3839946459113293,0.6724902109286491,0.08137704720652839,0.17169755104451068,1.0149975096355603,1.085314604290465,1.866928176818198,-0.2226723202632471,1.6258576473578923,-1.0294342081393086,-0.12508928118991622,1.029172877098212,0.7035921494358485,0.4304652245976121,-0.7499438782500567,-1.3808477342331456,3.284733395150704,0.4137558381966468,1.261829326445677,-0.06768439960582033,-1.4070886524662474,-0.3430464255779581,-1.005414393292386,-0.595242946157797,1.3532999391374014,0.6880742208527362,0.25993326491209245,1.3013270958737004,-1.077889444304914,0.34616397120861425,0.4471003091088909,-0.3025146589063486,1.1678883030223781,-1.053592111071168,3.5880722275384778,0.8552381999638872,-0.2824027254226025,-0.3634680295925095,-0.10586048643661662,2.2625294404559577,0.7650123908871262,-0.08672578350961495,0.9287404597149378,-0.3025146589063486,0.27733733002235417,0.5129086364034002,0.4471003091088909,1.4549503603205254,0.007563093228499072,0.17169755104451068,0.29466182574769184,-1.1269078629663312,1.7771424058672443,1.731319631584345,0.25993326491209245,-0.5736141057694272,0.34616397120861425,-0.08672578350961495,0.15380286431879417,0.4137558381966468,-0.8873409122764672,-0.5306993975719276,3.0902434831082837,0.5935621359363286,-1.4600530886095953,1.1542599074685331,-0.6388487645543015,0.9287404597149378,-0.12508928118991622,0.8403559612194028,1.8335441178353415,-0.3025146589063486,0.4304652245976121,1.1678883030223781,2.6402555038244877,-0.6388487645543015,-1.0294342081393086,2.101842136086416,-0.4462137510231218,-0.24248241020736983,2.0289249011183346,-0.6169874837196055,2.7676008494517013,0.15380286431879417,0.8254121420894225,2.16305244697371,2.0603772329418755,1.3143936999272097,0.04464637679634543,0.5935621359363286,-0.5520999295887415,1.181463958349545,-0.262392262257652,-1.3547654978043482,1.442407617676143,-0.3634680295925095,1.577900780996791,0.870059284479323,-0.048735570818035576,0.3801119112602281,3.1783138805528677,0.29466182574769184,1.9865073756421463,1.6377408954325872,-0.595242946157797,0.6724902109286491,1.1130548036372934,2.358972488129669,0.007563093228499072,0.31190736282418247,2.784180874695723,2.825233750109732,-0.4671696555646836,3.030006778420197,0.11776071457762759,0.9864762058893607,0.34616397120861425,0.6253369160329553,1.5536644399111408,0.34616397120861425,-0.18334808070797615,-0.5520999295887415,0.4965652697383779,1.5658043187937936,-1.3030706558113276
3,477
Passive transmembrane transporter activity
16
36
2.804794
0.005035
O75964,Q4KMQ2,P51798,Q9Y277,P45880,P51790,O96008,P24539,P00846,Q9UM00,P21796,P06576,Q96S66,P56385,Q8NE86,Q9C0H2
Functions
GO Molecular function
msigdb_gomf
32,389,586,250,12,108,527,339,20,701,23,655,607,283,547,31
2979,1283,32,527,20,655,1567,3275,2199,23,339,1569,942,2048,3434,12,2173,108,586,845,283,1170,2594,879,389,2358,547,1376,607,742,1554,31,995,701,250,3347
-0.8180718103176833,0.09961191055323138,3.141943931656318,0.8552381999638872,3.333065755789585,0.6724902109286491,-0.06768439960582033,-1.1516317262366567,-0.3839946459113293,3.284733395150704,1.261829326445677,-0.06768439960582033,0.34616397120861425,-0.3025146589063486,-1.7920825787050783,3.5880722275384778,-0.3634680295925095,2.2625294404559577,0.7650123908871262,0.4471003091088909,1.4549503603205254,0.17169755104451068,-0.5736141057694272,0.4137558381966468,1.1678883030223781,-0.4462137510231218,0.8254121420894225,0.04464637679634543,0.7344316400083396,0.5775714858809151,-0.048735570818035576,3.1783138805528677,0.31190736282418247,0.6253369160329553,1.5536644399111408,-1.3030706558113276
3,477
Electron transport
21
49
2.79857
0.005133
O75306,O43169,O96000,P00403,O43676,Q6DKK2,Q9NX14,P14927,Q9P0J0,Q9UDW1,O95864,O43920,O43396,Q9H3N1,Q9H1E5,Q86Y39,Q96CU9,O95169,O14949,Q9Y6M9,P21912
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
128,3,510,258,19,152,552,301,303,50,435,561,572,317,65,193,77,82,109,116,125
920,109,3,572,1000,19,3365,561,1995,128,1498,1355,582,82,3416,890,435,510,258,903,3418,830,2896,301,1828,125,2664,731,3393,2667,643,3235,2098,3249,861,696,2933,1341,2994,152,193,77,2562,65,317,552,303,50,116
0.363176231493417,2.252720884481982,3.9771842389586007,0.7802068776839349,0.29466182574769184,3.3399034479628043,-1.3808477342331456,0.795338037054623,-0.2824027254226025,2.0707936146461794,-0.02987854200342981,0.04464637679634543,0.7650123908871262,2.461737501871504,-1.6506750213514003,0.3969715892812894,1.0573549420901271,0.8848196367866663,1.5169816611056757,0.3801119112602281,-1.6785966185631933,0.4636616464692855,-0.7499438782500567,1.3789958573127592,-0.2029611534569842,2.0811764381859885,-0.6169874837196055,0.5775714858809151,-1.4867799433989366,-0.6169874837196055,0.6880742208527362,-1.077889444304914,-0.3227289322669874,-1.1023275684761824,0.4304652245976121,0.6253369160329553,-0.7725283500753476,0.0630554350483885,-0.8180718103176833,1.9326950418116124,1.7081694282043638,2.525404913107488,-0.5520999295887415,2.6489138234015064,1.3274111687020549,0.8254121420894225,1.3789958573127592,2.825233750109732,2.16305244697371
3,477
Monovalent inorganic cation homeostasis
9
29
2.790801
0.005258
P05023,P51790,Q9Y5X3,Q15904,O75503,Q93050,Q8N511,P50897,Q9Y487
Processes and pathways
GO Biological process
msigdb_gobp
291,108,272,270,47,17,79,26,123
47,386,1223,3092,291,655,2199,2542,2386,26,2247,108,1023,790,1438,2708,2804,270,79,507,17,1324,1976,916,2410,1279,123,272,3347
2.8495972795541524,1.1678883030223781,0.13582414108741372,-0.9106897973314252,1.4171833906612892,0.6724902109286491,-0.3839946459113293,-0.5520999295887415,-0.4671696555646836,3.2355640449184544,-0.4046271871534076,2.2625294404559577,0.27733733002235417,0.5129086364034002,0.007563093228499072,-0.6388487645543015,-0.6829258074091615,1.4798985250540877,2.4982794163821613,0.8995196748229518,3.373845322764859,0.08137704720652839,-0.262392262257652,0.3801119112602281,-0.4671696555646836,0.11776071457762759,2.101842136086416,1.4798985250540877,-1.3030706558113276
3,477
Cellular iron ion homeostasis
7
15
2.785922
0.005338
O75027,P02794,Q15043,P09601,Q8N511,Q9Y487,Q9Y5Y0
Processes and pathways
GO Biological process
msigdb_gobp
129,192,164,41,79,123,189
129,2464,3368,1163,192,41,2819,2622,2048,1438,164,270,79,123,189
2.0603772329418755,-0.5094115023895259,-1.3808477342331456,0.17169755104451068,1.7081694282043638,2.9762603054079118,-0.7051437292628466,-0.595242946157797,-0.3025146589063486,0.007563093228499072,1.8335441178353415,1.4798985250540877,2.4982794163821613,2.101842136086416,1.731319631584345
3,477