term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Selective autophagy
11
31
2.705072
0.006829
Q9NS69,Q9BUF5,Q96FJ2,Q99497,P19784,Q13404,P68371,P04350,O43237,Q13885,P50542
Processes and pathways
Reactome Pathways
msigdb_reactome
1,434,295,164,186,160,419,103,263,422,26
263,1226,2080,2412,3064,103,1307,3065,1916,451,186,2804,26,1182,1387,1119,1495,1188,587,419,160,2481,422,815,2682,295,3009,164,434,1,1366
1.1764179680733708,0.31566841450154726,-0.3628519054147641,-0.6432616792979482,-1.5703409161105824,1.631137115186846,0.2713697941390661,-1.5703409161105824,-0.22465358348725983,0.9230188420539016,1.3432048961451049,-1.0745728164819957,2.3501300710324777,0.35983999646262926,0.22694294684786878,0.40388571004367557,0.13769972233839525,0.35983999646262926,0.7948174485841241,0.9655270061034027,1.4259753991464208,-0.6905352848819015,0.9655270061034027,0.6222659574604167,-0.8812303292626974,1.1344567049048861,-1.4196669272842548,1.4259753991464208,0.9655270061034027,7.981408822541868,0.2713697941390661
3,216
Transcriptional regulation by runx3
34
46
2.699376
0.006947
Q99460,O00232,P25788,Q9UNM6,P28072,P35998,P49721,O43242,O00231,P61289,P25786,Q99436,P51665,P20618,P43686,P28066,P28074,P49720,Q9UL46,Q15008,O00233,P55036,P25787,P12931,P25789,O75832,P42771,P60900,Q13200,P62333,Q92530,P62195,Q06323,P25440
Processes and pathways
Reactome Pathways
msigdb_reactome
1074,376,637,566,638,639,39,1161,1017,915,794,723,1048,1175,1046,1037,1038,189,90,984,204,212,82,451,208,956,580,1122,981,586,513,584,354,1108
1017,376,204,1296,2517,1161,956,2771,451,1233,1175,1108,794,82,637,208,1037,1825,638,1038,2709,639,580,1046,1249,189,39,1048,212,1122,915,1186,584,586,354,2264,981,1556,2630,1330,984,513,723,1074,90,566
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,-0.7379672099364472,0.35983999646262926,0.4916041220297551,-1.0259824528918617,0.9230188420539016,0.31566841450154726,0.35983999646262926,0.40388571004367557,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,-0.9293131233315839,0.7518547618980741,0.7948174485841241,0.44780670716336934,0.31566841450154726,1.3432048961451049,2.1533494389689003,0.44780670716336934,1.301665163375922,0.40388571004367557,0.5352790715213577,0.35983999646262926,0.7948174485841241,0.7948174485841241,1.0502105964224744,-0.5023739774096585,0.4916041220297551,0.09288087174021684,-0.8333129569784509,0.2713697941390661,0.4916041220297551,0.880398505056007,0.7087759672510602,0.44780670716336934,1.7125124116396768,0.837665032712619
3,216
Proteasome regulatory particle
18
19
2.674514
0.007484
P48556,Q13200,Q99460,Q16186,O00232,O43242,P62333,O00231,P62195,P17980,Q9UNM6,Q15008,O00233,P51665,P55036,P43686,P62191,P35998
Localization
GO Cellular component
msigdb_gocc
1249,981,1074,654,376,1161,586,1017,584,1233,566,984,204,1048,212,1046,1186,639
1017,376,204,1296,1161,1233,639,1046,1249,1048,212,1186,584,586,981,984,654,1074,566
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,0.35983999646262926,0.31566841450154726,0.7518547618980741,0.44780670716336934,0.31566841450154726,0.44780670716336934,1.301665163375922,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.4916041220297551,0.4916041220297551,0.7518547618980741,0.44780670716336934,0.837665032712619
3,216
Auf1 hnrnp d0 binds and destabilizes mrna
32
43
2.671666
0.007548
Q99460,O00232,P25788,Q9UNM6,P28072,P35998,P49721,O43242,O00231,P61289,P25786,P51665,Q99436,P20618,P43686,P28066,P28074,P49720,Q9UL46,O00233,Q15008,P55036,P25787,P25789,O75832,P60900,Q13200,P62333,Q92530,P62195,Q06323,Q04637
Processes and pathways
Reactome Pathways
msigdb_reactome
1074,376,637,566,638,639,39,1161,1017,915,794,1048,723,1175,1046,1037,1038,189,90,204,984,212,82,208,956,1122,981,586,513,584,354,505
1017,376,204,1296,2517,1161,956,2802,1916,2253,1233,1175,794,82,637,208,1037,1825,638,1038,639,1046,1249,189,39,1048,212,1122,915,1186,584,586,505,354,981,2677,2373,984,513,723,1074,90,566
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,-0.7379672099364472,0.35983999646262926,0.4916041220297551,-1.0745728164819957,-0.22465358348725983,-0.5023739774096585,0.31566841450154726,0.35983999646262926,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,0.7518547618980741,0.44780670716336934,0.31566841450154726,1.3432048961451049,2.1533494389689003,0.44780670716336934,1.301665163375922,0.40388571004367557,0.5352790715213577,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.880398505056007,1.0502105964224744,0.4916041220297551,-0.8812303292626974,-0.5961446978316173,0.4916041220297551,0.880398505056007,0.7087759672510602,0.44780670716336934,1.7125124116396768,0.837665032712619
3,216
Positive regulation of protein catabolic process
40
66
2.663692
0.007729
Q9NZJ0,P48506,Q9BW61,Q96JB5,Q96QK1,Q9Y4X5,Q9UNE7,Q13190,P35998,P15311,P14735,O60826,Q8NEZ5,Q9ULT8,Q9NZL4,Q9Y5X1,P53634,O43847,O14965,P62877,Q13596,P26038,P63244,Q15370,O95816,P43686,Q7Z6Z7,P35241,Q9C0D3,O95352,Q9UNN5,O75925,O75832,Q06787,O75150,P62333,P46379,P62195,P45974,P55072
Processes and pathways
GO Biological process
msigdb_gobp
134,1114,139,936,938,1091,565,1056,639,1032,1031,897,294,1217,40,442,913,1022,787,418,421,795,537,424,1165,1046,600,1041,476,307,619,957,956,355,842,586,344,584,854,1119
787,1532,1022,897,842,2867,956,957,307,1228,1165,2352,1307,1817,1031,1032,1233,795,1041,639,1046,854,344,2423,1114,1833,2206,2478,1979,913,1119,1186,584,586,418,537,1553,355,1056,421,1329,2586,424,1453,2281,600,294,1462,1743,2498,936,938,2062,139,476,1855,134,40,1420,1959,1217,565,619,1091,2137,442
0.6222659574604167,0.09288087174021684,0.44780670716336934,0.5352790715213577,0.5788326555578377,-1.1722747921416414,0.4916041220297551,0.4916041220297551,1.0923878797824702,0.31566841450154726,0.35983999646262926,-0.5961446978316173,0.2713697941390661,-0.1332370713235067,0.44780670716336934,0.44780670716336934,0.31566841450154726,0.6222659574604167,0.44780670716336934,0.7518547618980741,0.44780670716336934,0.5788326555578377,1.0502105964224744,-0.6432616792979482,0.40388571004367557,-0.1332370713235067,-0.45571699704574653,-0.6905352848819015,-0.2705751034304403,0.5352790715213577,0.40388571004367557,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.9655270061034027,0.837665032712619,0.09288087174021684,1.0502105964224744,0.44780670716336934,0.9655270061034027,0.2713697941390661,-0.7855591810728211,0.9655270061034027,0.18238666517970953,-0.5023739774096585,0.7948174485841241,1.1344567049048861,0.18238666517970953,-0.04237989884272554,-0.6905352848819015,0.5352790715213577,0.5352790715213577,-0.31664072016034606,1.5083393975097876,0.9230188420539016,-0.1332370713235067,1.5493709586917743,2.1533494389689003,0.22694294684786878,-0.22465358348725983,0.35983999646262926,0.837665032712619,0.7948174485841241,0.44780670716336934,-0.3628519054147641,0.9655270061034027
3,216
Adenocarcinoma of the colon
6
21
2.657481
0.007873
P62854,P42766,P62857,P62081,P62899,P62847
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
127,4,104,75,48,53
1308,2664,1039,2778,4,704,2808,464,1980,1391,75,585,1496,53,127,104,48,1441,2156,980,272
0.2713697941390661,-0.8812303292626974,0.44780670716336934,-1.0259824528918617,3.707979800175326,0.7087759672510602,-1.0745728164819957,0.9230188420539016,-0.2705751034304403,0.22694294684786878,1.753055360618528,0.7948174485841241,0.13769972233839525,1.9543521336080658,1.5493709586917743,1.631137115186846,2.0342222402293983,0.18238666517970953,-0.40921015652470366,0.4916041220297551,1.1764179680733708
3,216
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
35
51
2.654467
0.007943
Q96DE5,Q99460,O00232,P25788,Q9UNM6,P28072,P35998,P49721,O43242,Q13309,O14965,O00231,P61289,P25786,Q99436,P51665,P20618,P43686,P28066,P28074,P49720,Q9UL46,O00233,Q15008,P55036,P25787,P25789,O75832,P60900,Q13200,P06400,P62333,Q92530,P62195,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
935,1074,376,637,566,638,639,39,1161,290,787,1017,915,794,723,1048,1175,1046,1037,1038,189,90,204,984,212,82,208,956,1122,981,341,586,513,584,354
1017,376,204,1296,2517,787,1161,956,341,1233,1175,794,82,637,208,1037,1825,638,1038,2418,639,1046,1249,189,39,1048,1979,212,1122,915,1186,584,586,354,2848,981,290,2373,984,513,935,723,1074,2126,2610,2185,1806,1807,1420,90,566
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,-0.7379672099364472,0.6222659574604167,0.35983999646262926,0.4916041220297551,1.0502105964224744,0.31566841450154726,0.35983999646262926,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,-0.6432616792979482,0.7518547618980741,0.44780670716336934,0.31566841450154726,1.3432048961451049,2.1533494389689003,0.44780670716336934,-0.2705751034304403,1.301665163375922,0.40388571004367557,0.5352790715213577,0.35983999646262926,0.7948174485841241,0.7948174485841241,1.0502105964224744,-1.1233362600271486,0.4916041220297551,1.1344567049048861,-0.5961446978316173,0.4916041220297551,0.880398505056007,0.5352790715213577,0.7087759672510602,0.44780670716336934,-0.3628519054147641,-0.7855591810728211,-0.40921015652470366,-0.0877392581795479,-0.0877392581795479,0.22694294684786878,1.7125124116396768,0.837665032712619
3,216
Protein polyubiquitination
21
57
2.647953
0.008098
Q9NZJ0,Q9BW61,Q8TDB6,Q9UNE7,Q8NEZ5,Q13404,P63208,Q13309,P62877,Q13616,Q9C0C9,Q7Z6Z7,Q8IU81,Q7Z7E8,P68036,O95155,P55786,Q13867,O95071,Q96FW1,P38398
Processes and pathways
GO Biological process
msigdb_gobp
134,139,18,565,294,160,159,290,418,540,331,600,604,319,465,74,86,214,573,107,115
2516,842,573,74,1228,1972,1823,971,2418,2709,115,977,86,2365,1721,1495,418,159,465,753,1882,2848,290,160,540,1559,214,1330,1331,2212,651,866,1197,600,319,604,294,18,107,2498,2062,3035,139,331,2126,2128,134,2610,2185,1806,1807,1420,1217,2341,565,779,1091
-0.7379672099364472,0.5788326555578377,0.7948174485841241,1.753055360618528,0.31566841450154726,-0.2705751034304403,-0.1332370713235067,0.4916041220297551,-0.6432616792979482,-0.9293131233315839,1.5903032740149434,0.4916041220297551,1.7125124116396768,-0.5961446978316173,-0.04237989884272554,0.13769972233839525,0.9655270061034027,1.4259753991464208,0.9230188420539016,0.6655800443025545,-0.17887471357436416,-1.1233362600271486,1.1344567049048861,1.4259753991464208,0.837665032712619,0.09288087174021684,1.301665163375922,0.2713697941390661,0.2713697941390661,-0.45571699704574653,0.7518547618980741,0.5788326555578377,0.35983999646262926,0.7948174485841241,1.0923878797824702,0.7948174485841241,1.1344567049048861,2.583450148616519,1.631137115186846,-0.6905352848819015,-0.31664072016034606,-1.4697004768647024,1.5083393975097876,1.0923878797824702,-0.3628519054147641,-0.3628519054147641,1.5493709586917743,-0.7855591810728211,-0.40921015652470366,-0.0877392581795479,-0.0877392581795479,0.22694294684786878,0.35983999646262926,-0.5491826755969934,0.837665032712619,0.6655800443025545,0.44780670716336934
3,216
Parkinubiquitin proteasomal system pathway
23
36
2.647062
0.008119
Q99460,O00232,P07437,Q9UNM6,Q9UNE7,P35998,Q9BUF5,P68371,O00231,Q13616,P34932,Q13885,P51665,P68036,Q15008,P55036,O00233,O75832,Q13200,P62333,P04350,P62195,Q0VDF9
Processes and pathways
WikiPathways
msigdb_wp
1074,376,267,566,565,639,434,419,1017,540,908,422,1048,465,984,212,204,956,981,586,103,584,253
1017,376,204,1296,2462,1161,956,103,267,1817,1916,1233,1316,908,639,2710,1046,1249,1048,1388,212,2365,1186,584,586,465,419,253,981,540,422,984,1074,434,565,566
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,-0.6905352848819015,0.35983999646262926,0.4916041220297551,1.631137115186846,1.1764179680733708,-0.1332370713235067,-0.22465358348725983,0.31566841450154726,0.2713697941390661,0.5352790715213577,0.7518547618980741,-0.9293131233315839,0.44780670716336934,0.31566841450154726,0.44780670716336934,0.22694294684786878,1.301665163375922,-0.5961446978316173,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.9230188420539016,0.9655270061034027,1.2182725531206917,0.4916041220297551,0.837665032712619,0.9655270061034027,0.4916041220297551,0.44780670716336934,0.9655270061034027,0.837665032712619,0.837665032712619
3,216
Regulation of amyloid precursor protein catabolic process
8
14
2.643584
0.008203
O95197,Q13526,P62942,Q96P70,P42574,P27695,O75116,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
7,591,10,326,703,147,572,333
572,7,1536,147,703,1716,10,757,921,591,2431,326,1072,333
0.7948174485841241,3.5618213976734334,0.09288087174021684,1.4672078084816735,0.7087759672510602,-0.04237989884272554,3.003616357853454,0.6655800443025545,0.5352790715213577,0.7948174485841241,-0.6432616792979482,1.0923878797824702,0.44780670716336934,1.0923878797824702
3,216
protease
33
44
2.638133
0.008336
Q9UNS2,Q99460,O00232,P25788,Q9BT78,Q9UNM6,Q9UQ80,P28072,P35998,Q7L266,Q9NQW7,P49721,O43242,P55210,P25786,Q99436,P20618,P43686,P28066,P28074,P49720,P42575,O00233,P55036,P42574,P25787,P25789,P50579,P55212,P60900,Q13200,P62333,P62195
Functions
Panther Protein class
panther_protein_class
281,1074,376,637,940,566,946,638,639,550,831,39,1161,535,794,723,1175,1046,1037,1038,189,85,204,212,703,82,208,461,93,1122,981,586,584
376,204,2517,1161,1871,2569,1233,1175,794,82,637,208,1037,1825,638,1038,639,703,85,1046,1249,189,39,461,212,535,93,1122,2846,1186,584,586,981,1838,550,723,1074,940,2607,2937,831,566,281,946
1.007923945841884,1.301665163375922,-0.7379672099364472,0.35983999646262926,-0.17887471357436416,-0.7855591810728211,0.31566841450154726,0.35983999646262926,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,0.7518547618980741,0.7087759672510602,1.7125124116396768,0.44780670716336934,0.31566841450154726,1.3432048961451049,2.1533494389689003,0.9230188420539016,1.301665163375922,0.837665032712619,1.671873243824585,0.40388571004367557,-1.1233362600271486,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.4916041220297551,-0.1332370713235067,0.837665032712619,0.7087759672510602,0.44780670716336934,0.5352790715213577,-0.7855591810728211,-1.2706853562868108,0.6222659574604167,0.837665032712619,1.1764179680733708,0.5352790715213577
3,216
Wnt signaling pathway
14
30
2.63634
0.008381
Q9HCK8,Q9UHD1,P19784,Q01970,P63208,P67870,Q9HB71,P62877,P30154,Q13616,Q13464,Q16537,O75116,P30153
Processes and pathways
KEGG Pathways
msigdb_kegg
301,409,186,252,159,587,518,418,268,540,757,257,572,453
572,2771,2353,1485,186,453,268,2709,1833,1255,1185,418,1836,159,587,252,1260,811,757,1556,1558,1674,540,1507,257,518,301,409,1420,947
0.7948174485841241,-1.0259824528918617,-0.5961446978316173,0.13769972233839525,1.3432048961451049,0.9230188420539016,1.1764179680733708,-0.9293131233315839,-0.1332370713235067,0.31566841450154726,0.35983999646262926,0.9655270061034027,-0.1332370713235067,1.4259753991464208,0.7948174485841241,1.2182725531206917,0.31566841450154726,0.6222659574604167,0.6655800443025545,0.09288087174021684,0.09288087174021684,0.0028423592723265142,0.837665032712619,0.13769972233839525,1.2182725531206917,0.880398505056007,1.1344567049048861,1.007923945841884,0.22694294684786878,0.5352790715213577
3,216
G1 to s cell cycle control
18
27
2.62558
0.00865
P14635,P42771,P06493,P49642,P49736,Q00534,Q14181,P49643,P35244,P06400,Q07864,P12004,P25205,P27694,P11802,P24941,O43929,P33991
Processes and pathways
WikiPathways
msigdb_wp
740,580,899,799,126,251,506,188,83,341,980,528,793,700,633,385,144,577
1654,144,2771,341,899,633,528,740,2525,385,793,700,577,1241,1488,83,580,799,188,126,2094,251,980,506,1450,2393,1085
0.0028423592723265142,1.4672078084816735,-1.0259824528918617,1.0502105964224744,0.5352790715213577,0.7518547618980741,0.837665032712619,0.6655800443025545,-0.7379672099364472,1.007923945841884,0.6222659574604167,0.7087759672510602,0.7948174485841241,0.31566841450154726,0.13769972233839525,1.7125124116396768,0.7948174485841241,0.6222659574604167,1.3432048961451049,1.5493709586917743,-0.3628519054147641,1.2182725531206917,0.4916041220297551,0.880398505056007,0.18238666517970953,-0.5961446978316173,0.44780670716336934
3,216
Ribosome
25
73
2.619863
0.008797
P62854,P26373,P42766,P62750,P62753,P62841,P62910,P46778,P15880,P63220,P46782,P62899,P62847,P61927,P61513,Q9Y3U8,P60866,P84098,P62081,P25398,P46777,P62857,P62244,P62269,P05388
Processes and pathways
KEGG Pathways
msigdb_kegg
127,744,4,392,270,22,150,148,635,647,416,48,53,803,708,621,464,76,75,699,704,104,585,503,113
3128,113,1308,1610,635,2664,2086,904,1034,699,744,906,1540,1826,1828,2360,2778,1713,2574,4,1181,704,148,1434,1385,416,2808,1664,1544,1116,464,978,1980,1391,708,803,75,1187,585,1981,1326,503,1496,1620,804,1393,1257,392,270,1497,22,53,1498,127,104,1499,858,48,1050,150,1441,1125,1927,647,1189,1879,76,2715,1672,2156,2935,3040,621
-1.8770253627023152,1.5903032740149434,0.2713697941390661,0.04792884656143651,0.7518547618980741,-0.8812303292626974,-0.3628519054147641,0.5352790715213577,0.44780670716336934,0.7087759672510602,0.6655800443025545,0.5352790715213577,0.09288087174021684,-0.1332370713235067,-0.1332370713235067,-0.5961446978316173,-1.0259824528918617,-0.04237989884272554,-0.7855591810728211,3.707979800175326,0.35983999646262926,0.7087759672510602,1.4672078084816735,0.18238666517970953,0.22694294684786878,0.9655270061034027,-1.0745728164819957,0.0028423592723265142,0.09288087174021684,0.40388571004367557,0.9230188420539016,0.4916041220297551,-0.2705751034304403,0.22694294684786878,0.7087759672510602,0.6222659574604167,1.753055360618528,0.35983999646262926,0.7948174485841241,-0.2705751034304403,0.2713697941390661,0.880398505056007,0.13769972233839525,0.04792884656143651,0.6222659574604167,0.22694294684786878,0.31566841450154726,1.007923945841884,1.1764179680733708,0.13769972233839525,2.428239255449916,1.9543521336080658,0.13769972233839525,1.5493709586917743,1.631137115186846,0.13769972233839525,0.5788326555578377,2.0342222402293983,0.44780670716336934,1.4672078084816735,0.18238666517970953,0.40388571004367557,-0.22465358348725983,0.7518547618980741,0.35983999646262926,-0.17887471357436416,1.753055360618528,-0.9293131233315839,0.0028423592723265142,-0.40921015652470366,-1.2706853562868108,-1.4697004768647024,0.7948174485841241
3,216
Autophagy
16
48
2.607401
0.009123
Q9NS69,Q9BUF5,Q96FJ2,Q99497,P19784,Q13404,O95352,P68371,P04350,Q99816,O43237,P60520,Q6IAA8,Q13885,P50542,Q9NT62
Processes and pathways
Reactome Pathways
msigdb_reactome
1,434,295,164,186,160,307,419,103,15,263,351,118,422,26,372
263,1226,2080,2412,307,3064,103,1307,1168,3065,1916,451,186,2804,1180,2091,26,1182,1387,1119,351,1495,1188,587,419,1555,160,2481,422,815,118,2682,3186,2910,2111,295,2116,3009,164,1280,15,434,1,372,2242,2511,567,1366
1.1764179680733708,0.31566841450154726,-0.3628519054147641,-0.6432616792979482,1.0923878797824702,-1.5703409161105824,1.631137115186846,0.2713697941390661,0.35983999646262926,-1.5703409161105824,-0.22465358348725983,0.9230188420539016,1.3432048961451049,-1.0745728164819957,0.35983999646262926,-0.3628519054147641,2.3501300710324777,0.35983999646262926,0.22694294684786878,0.40388571004367557,1.0502105964224744,0.13769972233839525,0.35983999646262926,0.7948174485841241,0.9655270061034027,0.09288087174021684,1.4259753991464208,-0.6905352848819015,0.9655270061034027,0.6222659574604167,1.5903032740149434,-0.8812303292626974,-2.405349762622622,-1.2213904611668245,-0.3628519054147641,1.1344567049048861,-0.3628519054147641,-1.4196669272842548,1.4259753991464208,0.31566841450154726,2.62204635312281,0.9655270061034027,7.981408822541868,1.0502105964224744,-0.45571699704574653,-0.6905352848819015,0.837665032712619,0.2713697941390661
3,216
Persistence of hemoglobin f
6
21
2.60646
0.009148
P62854,P42766,P62857,P62081,P62899,P62847
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
127,4,104,75,48,53
1308,2664,2778,4,704,2808,464,749,1980,1391,75,585,1496,53,127,104,48,1441,2156,292,1364
0.2713697941390661,-0.8812303292626974,-1.0259824528918617,3.707979800175326,0.7087759672510602,-1.0745728164819957,0.9230188420539016,0.6655800443025545,-0.2705751034304403,0.22694294684786878,1.753055360618528,0.7948174485841241,0.13769972233839525,1.9543521336080658,1.5493709586917743,1.631137115186846,2.0342222402293983,0.18238666517970953,-0.40921015652470366,1.1344567049048861,0.2713697941390661
3,216
E2f mediated regulation of dna replication
10
12
2.605526
0.009173
P14635,P06493,P49642,Q14181,P49643,P06400,O43929,P30154,P09884,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
740,899,799,506,188,341,144,268,632,453
1654,144,341,899,632,740,453,268,799,188,506,1085
0.0028423592723265142,1.4672078084816735,1.0502105964224744,0.5352790715213577,0.7518547618980741,0.6655800443025545,0.9230188420539016,1.1764179680733708,0.6222659574604167,1.3432048961451049,0.880398505056007,0.44780670716336934
3,216
Adenocarcinoma of the intestines
9
24
2.586844
0.009686
P62854,P42766,P60866,P62857,P62081,Q6PD74,P62899,P62847,P43246
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
127,4,464,104,75,272,48,53,581
1308,2664,1039,2778,4,581,704,2808,464,1980,1391,75,585,1496,53,127,104,48,1441,1550,2156,980,1556,272
0.2713697941390661,-0.8812303292626974,0.44780670716336934,-1.0259824528918617,3.707979800175326,0.7948174485841241,0.7087759672510602,-1.0745728164819957,0.9230188420539016,-0.2705751034304403,0.22694294684786878,1.753055360618528,0.7948174485841241,0.13769972233839525,1.9543521336080658,1.5493709586917743,1.631137115186846,2.0342222402293983,0.18238666517970953,0.09288087174021684,-0.40921015652470366,0.4916041220297551,0.09288087174021684,1.1764179680733708
3,216
Interleukin 17 signaling
8
14
2.586446
0.009697
Q13404,P51452,Q02750,P63208,P28482,Q13616,P30154,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
160,642,752,159,796,540,268,453
1298,796,453,268,642,1495,159,752,160,540,1507,1568,865,1931
0.2713697941390661,0.6222659574604167,0.9230188420539016,1.1764179680733708,0.7518547618980741,0.13769972233839525,1.4259753991464208,0.6655800443025545,1.4259753991464208,0.837665032712619,0.13769972233839525,0.09288087174021684,0.5788326555578377,-0.22465358348725983
3,216
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s
18
52
2.580784
0.009858
Q9UBQ5,P63220,P62854,Q04637,O75821,P60866,P62857,P62081,Q14152,P62244,P46782,P62753,Q7L2H7,P06730,P62841,P62847,P62269,P15880
Processes and pathways
Reactome Pathways
msigdb_reactome
408,647,127,505,687,464,104,75,713,585,416,270,662,630,22,53,503,635
1423,1754,1019,687,1375,1229,630,1308,1610,2253,635,1174,1034,2310,699,2778,1112,1385,416,2808,1668,1547,1121,1390,464,978,75,1187,585,1981,1392,1326,503,1496,1620,804,1257,270,22,53,1498,127,104,1499,647,505,1504,713,1448,662,408,1089
0.18238666517970953,-0.0877392581795479,0.44780670716336934,0.7087759672510602,0.22694294684786878,0.31566841450154726,0.7518547618980741,0.2713697941390661,0.04792884656143651,-0.5023739774096585,0.7518547618980741,0.35983999646262926,0.44780670716336934,-0.5491826755969934,0.7087759672510602,-1.0259824528918617,0.40388571004367557,0.22694294684786878,0.9655270061034027,-1.0745728164819957,0.0028423592723265142,0.09288087174021684,0.40388571004367557,0.22694294684786878,0.9230188420539016,0.4916041220297551,1.753055360618528,0.35983999646262926,0.7948174485841241,-0.2705751034304403,0.22694294684786878,0.2713697941390661,0.880398505056007,0.13769972233839525,0.04792884656143651,0.6222659574604167,0.31566841450154726,1.1764179680733708,2.428239255449916,1.9543521336080658,0.13769972233839525,1.5493709586917743,1.631137115186846,0.13769972233839525,0.7518547618980741,0.880398505056007,0.13769972233839525,0.7087759672510602,0.18238666517970953,0.7518547618980741,1.007923945841884,0.44780670716336934
3,216
Positive regulation of proteolysis involved in cellular protein catabolic process
29
41
2.575794
0.010001
P48506,Q9BW61,Q96JB5,Q9Y4X5,Q9UNE7,P35998,O60826,Q8NEZ5,Q9ULT8,Q9NZL4,P53634,O14965,P62877,O95816,P63244,Q15370,P43686,P62191,Q9C0D3,O75925,O75832,Q06787,O75150,P62333,P46379,P62195,P17980,P45974,P55072
Processes and pathways
GO Biological process
msigdb_gobp
1114,139,936,1091,565,639,897,294,1217,40,913,787,418,1165,537,424,1046,1186,476,957,956,355,842,586,344,584,1233,854,1119
787,1532,897,842,956,957,1228,1165,2352,1817,1233,639,1046,854,344,1114,1833,2478,1979,913,1119,1186,584,586,418,537,1553,355,2586,424,2281,294,1743,936,139,476,40,1217,565,1091,2137
0.6222659574604167,0.09288087174021684,0.5352790715213577,0.5788326555578377,0.4916041220297551,0.4916041220297551,0.31566841450154726,0.35983999646262926,-0.5961446978316173,-0.1332370713235067,0.31566841450154726,0.7518547618980741,0.44780670716336934,0.5788326555578377,1.0502105964224744,0.40388571004367557,-0.1332370713235067,-0.6905352848819015,-0.2705751034304403,0.5352790715213577,0.40388571004367557,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.9655270061034027,0.837665032712619,0.09288087174021684,1.0502105964224744,-0.7855591810728211,0.9655270061034027,-0.5023739774096585,1.1344567049048861,-0.04237989884272554,0.5352790715213577,1.5083393975097876,0.9230188420539016,2.1533494389689003,0.35983999646262926,0.837665032712619,0.44780670716336934,-0.3628519054147641
3,216
Nucleoside monophosphate metabolic process
18
38
2.564528
0.010332
Q9BZX2,P22102,P60891,Q01433,O43598,Q9Y3D8,P30520,P12268,Q9UDY2,P04183,O76075,P11908,P00492,P32321,P49915,P20839,P31939,P34896
Processes and pathways
GO Biological process
msigdb_gobp
405,742,646,311,125,71,500,495,59,340,227,229,628,388,210,636,576,454
2462,1160,125,227,1535,628,1482,340,1609,1099,1170,229,495,636,742,1107,1237,1431,907,500,1487,576,388,1240,454,747,210,3168,1324,646,311,1052,2875,1891,405,1475,59,71
-0.6905352848819015,0.35983999646262926,1.5493709586917743,1.2600213316709783,0.09288087174021684,0.7518547618980741,0.13769972233839525,1.0502105964224744,0.04792884656143651,0.40388571004367557,0.35983999646262926,1.2600213316709783,0.880398505056007,0.7518547618980741,0.6655800443025545,0.40388571004367557,0.31566841450154726,0.18238666517970953,0.5352790715213577,0.880398505056007,0.13769972233839525,0.7948174485841241,1.007923945841884,0.31566841450154726,0.9230188420539016,0.6655800443025545,1.301665163375922,-2.1913012449877596,0.2713697941390661,0.7518547618980741,1.0923878797824702,0.44780670716336934,-1.1722747921416414,-0.17887471357436416,1.007923945841884,0.18238666517970953,1.874114172198667,1.7935028231987427
3,216
Protein neddylation
6
8
2.563964
0.010348
Q9BTE7,Q13564,P62877,Q8TBC4,P61081,Q96GG9
Processes and pathways
GO Biological process
msigdb_gobp
404,712,418,362,390,296
704,390,418,1441,712,362,296,404
0.7087759672510602,1.007923945841884,0.9655270061034027,0.18238666517970953,0.7087759672510602,1.0502105964224744,1.1344567049048861,1.007923945841884
3,216
Activation of atr in response to replication stress
10
18
2.553808
0.010655
O14757,P40937,P49736,P35250,P35249,P27694,P35244,P24941,O43929,P33991
Processes and pathways
Reactome Pathways
msigdb_reactome
246,702,126,455,745,700,83,385,144,577
246,1654,144,2525,385,793,700,577,1241,1488,83,745,455,702,1045,126,1450,1085
1.2182725531206917,0.0028423592723265142,1.4672078084816735,-0.7379672099364472,1.007923945841884,0.6222659574604167,0.7087759672510602,0.7948174485841241,0.31566841450154726,0.13769972233839525,1.7125124116396768,0.6655800443025545,0.9230188420539016,0.7087759672510602,0.44780670716336934,1.5493709586917743,0.18238666517970953,0.44780670716336934
3,216
Dendritic spine development
12
25
2.546185
0.010891
Q9UQB8,A0AVT1,P62330,Q9UJU6,O00401,Q05086,Q9NUL3,O60678,Q06787,Q00535,Q92769,P61160
Processes and pathways
GO Biological process
msigdb_gobp
374,837,750,410,524,753,482,185,355,860,998,536
837,524,185,2034,1710,1236,974,1325,536,750,1442,860,753,355,1397,1726,1563,1567,1781,998,1949,2015,482,410,374
0.5788326555578377,0.837665032712619,1.3432048961451049,-0.31664072016034606,-0.04237989884272554,0.31566841450154726,0.4916041220297551,0.2713697941390661,0.837665032712619,0.6655800443025545,0.18238666517970953,0.5788326555578377,0.6655800443025545,1.0502105964224744,0.22694294684786878,-0.04237989884272554,0.09288087174021684,0.09288087174021684,-0.0877392581795479,0.4916041220297551,-0.22465358348725983,-0.2705751034304403,0.9230188420539016,1.007923945841884,1.0502105964224744
3,216
Mapk family signaling cascades
61
98
2.540698
0.011063
P41240,Q02750,Q99460,O00232,P25788,Q99956,Q9UQ13,P30154,Q9UNM6,P28072,P35998,P06493,P49721,O14980,P46940,O43242,P28482,O00231,P61289,P62877,Q96P70,P25786,P51665,Q99436,P43686,P20618,P62191,P28066,Q16181,P28074,P21359,Q92796,P49720,P30086,Q9UL46,Q9Y490,O00233,P55036,Q15008,P25787,P12931,P25789,P30153,O75832,P60900,Q13200,P62140,P62333,P13591,P62195,Q92530,P10398,Q01082,Q9Y4G8,Q06124,P18433,Q06323,P32121,Q96S59,Q16537,P53041
Processes and pathways
Reactome Pathways
msigdb_reactome
1113,752,1074,376,637,275,1088,268,566,638,639,899,39,1159,286,1161,796,1017,915,418,326,794,1048,723,1046,1175,1186,1037,470,1038,68,608,189,309,90,622,204,212,984,82,451,208,453,956,1122,981,1124,586,967,584,513,1102,861,521,353,1106,354,972,1072,257,1118
1017,376,204,1296,2517,1159,1161,2030,1302,956,2620,2802,899,1102,451,967,1485,1233,1820,1106,1175,68,1176,794,82,637,208,1824,1037,1825,638,1038,796,309,453,268,1661,972,2842,639,2205,2668,2734,1113,1046,286,1249,189,39,1048,1118,212,1122,1325,915,1124,1186,584,586,418,2427,1836,861,752,1553,353,354,1726,981,1558,1674,1559,1929,2875,1507,2373,984,1567,470,1993,257,2979,513,608,326,1072,723,1074,275,1584,2339,1957,90,566,1088,2511,622,521
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,-0.7379672099364472,0.35983999646262926,0.35983999646262926,-0.31664072016034606,0.2713697941390661,0.4916041220297551,-0.8333129569784509,-1.0745728164819957,0.5352790715213577,0.40388571004367557,0.9230188420539016,0.4916041220297551,0.13769972233839525,0.31566841450154726,-0.1332370713235067,0.40388571004367557,0.35983999646262926,1.7935028231987427,0.35983999646262926,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,-0.1332370713235067,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,0.6222659574604167,1.0923878797824702,0.9230188420539016,1.1764179680733708,0.0028423592723265142,0.4916041220297551,-1.1233362600271486,0.7518547618980741,-0.45571699704574653,-0.8812303292626974,-0.977563199292741,0.40388571004367557,0.44780670716336934,1.1344567049048861,0.31566841450154726,1.3432048961451049,2.1533494389689003,0.44780670716336934,0.40388571004367557,1.301665163375922,0.40388571004367557,0.2713697941390661,0.5352790715213577,0.40388571004367557,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.9655270061034027,-0.6432616792979482,-0.1332370713235067,0.5788326555578377,0.6655800443025545,0.09288087174021684,1.0502105964224744,1.0502105964224744,-0.04237989884272554,0.4916041220297551,0.09288087174021684,0.0028423592723265142,0.09288087174021684,-0.22465358348725983,-1.1722747921416414,0.13769972233839525,-0.5961446978316173,0.4916041220297551,0.09288087174021684,0.9230188420539016,-0.2705751034304403,1.2182725531206917,-1.369821392742899,0.880398505056007,0.7948174485841241,1.0923878797824702,0.44780670716336934,0.7087759672510602,0.44780670716336934,1.1764179680733708,0.09288087174021684,-0.5491826755969934,-0.22465358348725983,1.7125124116396768,0.837665032712619,0.44780670716336934,-0.6905352848819015,0.7948174485841241,0.880398505056007
3,216
Negative regulation of cellular protein catabolic process
15
30
2.538538
0.011132
P54578,Q86UE8,Q99497,P19784,O14908,Q9UL15,Q96JB5,P78559,P62081,P46379,Q96KB5,Q92530,P60520,P46777,Q9Y5K5
Processes and pathways
GO Biological process
msigdb_gobp
249,763,164,186,840,142,936,289,75,344,178,513,351,704,336
840,1018,1019,1532,1303,2773,1168,186,344,704,249,351,75,1497,1441,289,2429,763,2053,513,2685,1742,1743,936,178,938,164,1471,142,336
0.5788326555578377,0.44780670716336934,0.44780670716336934,0.09288087174021684,0.2713697941390661,-1.0259824528918617,0.35983999646262926,1.3432048961451049,1.0502105964224744,0.7087759672510602,1.2182725531206917,1.0502105964224744,1.753055360618528,0.13769972233839525,0.18238666517970953,1.1344567049048861,-0.6432616792979482,0.6655800443025545,-0.31664072016034606,0.880398505056007,-0.8812303292626974,-0.04237989884272554,-0.04237989884272554,0.5352790715213577,1.3846413663706636,0.5352790715213577,1.4259753991464208,0.18238666517970953,1.5083393975097876,1.0923878797824702
3,216
Intraflagellar transport
6
11
2.530777
0.011381
Q9BUF5,Q96FJ2,P68371,P04350,Q13885,Q9Y547
Processes and pathways
Reactome Pathways
msigdb_reactome
434,295,419,103,422,100
103,1188,419,422,1575,1275,295,434,670,1220,100
1.631137115186846,0.35983999646262926,0.9655270061034027,0.9655270061034027,0.09288087174021684,0.31566841450154726,1.1344567049048861,0.9655270061034027,0.7518547618980741,0.35983999646262926,1.671873243824585
3,216
Negative regulation of proteasomal protein catabolic process
8
22
2.527375
0.011492
P54578,Q99497,Q9UL15,P78559,P46379,Q96KB5,P60520,Q9Y5K5
Processes and pathways
GO Biological process
msigdb_gobp
249,164,142,289,344,178,351,336
840,1018,1019,1532,1303,1168,344,249,351,1441,289,2429,763,2053,513,2685,1742,1743,178,164,142,336
0.5788326555578377,0.44780670716336934,0.44780670716336934,0.09288087174021684,0.2713697941390661,0.35983999646262926,1.0502105964224744,1.2182725531206917,1.0502105964224744,0.18238666517970953,1.1344567049048861,-0.6432616792979482,0.6655800443025545,-0.31664072016034606,0.880398505056007,-0.8812303292626974,-0.04237989884272554,-0.04237989884272554,1.3846413663706636,1.4259753991464208,1.5083393975097876,1.0923878797824702
3,216
Cytosolic small ribosomal subunit
12
32
2.522357
0.011657
P63220,P62854,P60866,P62857,P62081,P62244,P46782,P62753,P62847,P62841,P62269,P15880
Localization
GO Cellular component
msigdb_gocc
647,127,464,104,75,585,416,270,53,22,503,635
1229,1308,1610,635,1034,699,2778,1385,416,2808,464,978,75,1187,585,1981,1392,1326,503,1496,1620,804,1257,270,22,53,1498,127,104,647,2095,1145
0.31566841450154726,0.2713697941390661,0.04792884656143651,0.7518547618980741,0.44780670716336934,0.7087759672510602,-1.0259824528918617,0.22694294684786878,0.9655270061034027,-1.0745728164819957,0.9230188420539016,0.4916041220297551,1.753055360618528,0.35983999646262926,0.7948174485841241,-0.2705751034304403,0.22694294684786878,0.2713697941390661,0.880398505056007,0.13769972233839525,0.04792884656143651,0.6222659574604167,0.31566841450154726,1.1764179680733708,2.428239255449916,1.9543521336080658,0.13769972233839525,1.5493709586917743,1.631137115186846,0.7518547618980741,-0.3628519054147641,0.40388571004367557
3,216
Abnormal hemoglobin
7
26
2.519764
0.011743
Q9UKG1,P62854,P42766,P62857,P62081,P62899,P62847
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
303,127,4,104,75,48,53
2407,1872,1308,2664,2778,4,2260,704,2808,464,749,1980,1391,75,585,1496,53,127,104,48,1441,2156,292,2603,303,1364
-0.6432616792979482,-0.17887471357436416,0.2713697941390661,-0.8812303292626974,-1.0259824528918617,3.707979800175326,-0.5023739774096585,0.7087759672510602,-1.0745728164819957,0.9230188420539016,0.6655800443025545,-0.2705751034304403,0.22694294684786878,1.753055360618528,0.7948174485841241,0.13769972233839525,1.9543521336080658,1.5493709586917743,1.631137115186846,2.0342222402293983,0.18238666517970953,-0.40921015652470366,1.1344567049048861,-0.7855591810728211,1.1344567049048861,0.2713697941390661
3,216
Amyloid beta formation
7
9
2.513411
0.011957
O95197,Q13526,Q13464,P42574,P27695,O75116,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
7,591,757,703,147,572,333
572,7,147,703,1716,757,921,591,333
0.7948174485841241,3.5618213976734334,1.4672078084816735,0.7087759672510602,-0.04237989884272554,0.6655800443025545,0.5352790715213577,0.7948174485841241,1.0923878797824702
3,216
Regulation of extrinsic apoptotic signaling pathway in absence of ligand
6
11
2.512036
0.012004
Q86WB0,Q99504,P21359,P30154,P30153,Q13546
Processes and pathways
GO Biological process
msigdb_gobp
131,38,68,268,453,254
1817,68,453,268,1320,1977,709,918,254,131,38
-0.1332370713235067,1.7935028231987427,0.9230188420539016,1.1764179680733708,0.2713697941390661,-0.2705751034304403,0.7087759672510602,0.5352790715213577,1.2182725531206917,1.5493709586917743,2.1928803390588034
3,216
Deoxyribose phosphate metabolic process
8
18
2.510353
0.012061
Q96G03,P31350,Q9H773,P62380,P32321,Q96DE0,P34896,Q9Y315
Processes and pathways
GO Biological process
msigdb_gobp
721,414,558,352,388,24,454,168
1535,1609,790,1237,1238,414,388,1240,454,1324,352,1550,1891,24,721,558,168,1090
0.09288087174021684,0.04792884656143651,0.6222659574604167,0.31566841450154726,0.31566841450154726,0.9655270061034027,1.007923945841884,0.31566841450154726,0.9230188420539016,0.2713697941390661,1.0502105964224744,0.09288087174021684,-0.17887471357436416,2.389227131656879,0.7087759672510602,0.837665032712619,1.4259753991464208,0.44780670716336934
3,216
Cyclin dependent protein kinase holoenzyme complex
9
12
2.510111
0.012069
P14635,Q9NYV4,P49736,Q00534,Q9P287,P12004,Q00535,P11802,P24941
Localization
GO Cellular component
msigdb_gocc
740,437,126,251,110,528,860,633,385
1759,899,633,528,740,385,126,1047,251,860,437,110
-0.0877392581795479,0.5352790715213577,0.7518547618980741,0.837665032712619,0.6655800443025545,1.007923945841884,1.5493709586917743,0.44780670716336934,1.2182725531206917,0.5788326555578377,0.9655270061034027,1.631137115186846
3,216
Mitotic dna replication
6
10
2.508741
0.012116
P18858,O75844,Q9BRX5,P49736,P09884,P33991
Processes and pathways
GO Biological process
msigdb_gobp
741,62,473,126,632,577
62,632,741,793,577,1488,126,1450,473,1641
1.8338555224412796,0.7518547618980741,0.6655800443025545,0.6222659574604167,0.7948174485841241,0.13769972233839525,1.5493709586917743,0.18238666517970953,0.9230188420539016,0.04792884656143651
3,216
Iron uptake and transport
6
17
2.505078
0.012242
Q93050,P63208,P30519,O76003,P21283,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
471,159,9,101,697,540
101,1704,1029,1822,697,1430,9,1876,1433,1670,159,540,1676,870,471,1526,2136
1.631137115186846,-0.04237989884272554,0.44780670716336934,-0.1332370713235067,0.7087759672510602,0.18238666517970953,3.191510823142953,-0.17887471357436416,0.18238666517970953,0.0028423592723265142,1.4259753991464208,0.837665032712619,0.0028423592723265142,0.5788326555578377,0.9230188420539016,0.13769972233839525,-0.3628519054147641
3,216
Lagging strand synthesis
13
19
2.499669
0.012431
P18858,P40937,P35250,Q14181,P35249,P49643,P49005,P27694,P12004,P39748,P09884,P35244,Q15054
Processes and pathways
Reactome Pathways
msigdb_reactome
741,702,455,506,745,188,640,700,528,171,632,83,468
632,528,2525,741,700,1039,83,745,455,1489,171,702,1045,640,799,188,506,468,2862
0.7518547618980741,0.837665032712619,-0.7379672099364472,0.6655800443025545,0.7087759672510602,0.44780670716336934,1.7125124116396768,0.6655800443025545,0.9230188420539016,0.13769972233839525,1.3846413663706636,0.7087759672510602,0.44780670716336934,0.7518547618980741,0.6222659574604167,1.3432048961451049,0.880398505056007,0.9230188420539016,-1.1233362600271486
3,216
External ear malformation
7
15
2.496375
0.012547
Q9NVI1,P40855,Q15813,P07437,Q15555,P38398,P50542
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
615,532,291,267,173,115,26
1024,267,2143,2088,115,532,579,26,1190,1397,173,291,2543,615,1644
0.44780670716336934,1.1764179680733708,-0.40921015652470366,-0.3628519054147641,1.5903032740149434,0.837665032712619,0.7948174485841241,2.3501300710324777,0.35983999646262926,0.22694294684786878,1.3846413663706636,1.1344567049048861,-0.7379672099364472,0.7948174485841241,0.04792884656143651
3,216
Parkinsons disease pathway
6
12
2.492878
0.012671
P55212,Q99497,P68036,P55210,O14727,P42575
Processes and pathways
WikiPathways
msigdb_wp
93,164,465,535,47,85
47,1658,1316,703,85,535,93,2365,465,1931,164,1518
2.0342222402293983,0.0028423592723265142,0.2713697941390661,0.7087759672510602,1.7125124116396768,0.837665032712619,1.671873243824585,-0.5961446978316173,0.9230188420539016,-0.22465358348725983,1.4259753991464208,0.13769972233839525
3,216
Ubiquitin protein transferase regulator activity
6
11
2.486103
0.012915
P60866,P62081,Q92990,P68036,P62841,P46777
Functions
GO Molecular function
msigdb_gomf
464,75,515,465,22,704
704,464,803,75,1497,22,1441,465,515,1688,2071
0.7087759672510602,0.9230188420539016,0.6222659574604167,1.753055360618528,0.13769972233839525,2.428239255449916,0.18238666517970953,0.9230188420539016,0.880398505056007,0.0028423592723265142,-0.31664072016034606
3,216
Osteosarcoma
6
25
2.48573
0.012929
Q13126,P42766,P62857,P62081,P62899,P62847
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
36,4,104,75,48,53
2194,3045,2771,341,1308,2664,2778,4,580,704,2808,464,1980,1391,75,585,1496,53,127,104,48,1441,2156,36,2126
-0.45571699704574653,-1.5199243531109388,-1.0259824528918617,1.0502105964224744,0.2713697941390661,-0.8812303292626974,-1.0259824528918617,3.707979800175326,0.7948174485841241,0.7087759672510602,-1.0745728164819957,0.9230188420539016,-0.2705751034304403,0.22694294684786878,1.753055360618528,0.7948174485841241,0.13769972233839525,1.9543521336080658,1.5493709586917743,1.631137115186846,2.0342222402293983,0.18238666517970953,-0.40921015652470366,2.1928803390588034,-0.3628519054147641
3,216
Resolution of abasic sites ap sites
20
30
2.482943
0.01303
P18858,P35249,P29372,P27695,P49005,P12004,P13051,P40938,P39748,Q86W56,Q15054,P40937,Q9NX46,P27694,P35244,Q9UGN5,P35250,Q9NR33,Q07864,P18887
Processes and pathways
Reactome Pathways
msigdb_reactome
741,745,137,147,640,528,790,1045,171,995,468,702,1010,700,83,99,455,772,980,849
1309,528,790,2525,741,849,700,147,1039,137,83,745,455,1489,171,702,1045,640,1834,2094,1550,980,468,995,2121,772,2645,1010,99,2862
0.2713697941390661,0.837665032712619,0.6222659574604167,-0.7379672099364472,0.6655800443025545,0.5788326555578377,0.7087759672510602,1.4672078084816735,0.44780670716336934,1.5083393975097876,1.7125124116396768,0.6655800443025545,0.9230188420539016,0.13769972233839525,1.3846413663706636,0.7087759672510602,0.44780670716336934,0.7518547618980741,-0.1332370713235067,-0.3628519054147641,0.09288087174021684,0.4916041220297551,0.9230188420539016,0.4916041220297551,-0.3628519054147641,0.6655800443025545,-0.8333129569784509,0.4916041220297551,1.671873243824585,-1.1233362600271486
3,216
Macrocytic anemia
14
34
2.481423
0.013086
P62854,P42766,Q5F1R6,O43175,P61011,P60866,P62857,P62081,P62244,P62899,P00492,O00429,P62847,P46777
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
127,4,292,684,749,464,104,75,585,48,628,443,53,704
443,684,2193,628,1308,1170,1103,2664,1316,2778,4,704,2808,464,749,1980,1391,75,585,1392,1496,53,127,104,48,1441,2156,292,2168,993,825,1285,1364,2344
0.9230188420539016,0.7087759672510602,-0.45571699704574653,0.7518547618980741,0.2713697941390661,0.35983999646262926,0.40388571004367557,-0.8812303292626974,0.2713697941390661,-1.0259824528918617,3.707979800175326,0.7087759672510602,-1.0745728164819957,0.9230188420539016,0.6655800443025545,-0.2705751034304403,0.22694294684786878,1.753055360618528,0.7948174485841241,0.22694294684786878,0.13769972233839525,1.9543521336080658,1.5493709586917743,1.631137115186846,2.0342222402293983,0.18238666517970953,-0.40921015652470366,1.1344567049048861,-0.40921015652470366,0.4916041220297551,0.6222659574604167,0.31566841450154726,0.2713697941390661,-0.5491826755969934
3,216
Protein kinase complex
19
27
2.469646
0.013525
P14635,P49736,Q00534,P11802,P24941,P06493,Q9NYV4,Q93100,P12004,P12956,P50750,P54619,P13010,O15111,P18074,Q96T76,Q9P287,Q00535,Q92759
Localization
GO Cellular component
msigdb_gocc
740,126,251,633,385,899,437,719,528,1171,1047,1182,1310,1298,1313,1413,110,860,931
1298,1759,899,1763,633,528,1171,1310,1707,740,1313,1973,385,126,1047,1182,1387,1722,251,860,1555,931,719,1413,437,110,2070
0.2713697941390661,-0.0877392581795479,0.5352790715213577,-0.0877392581795479,0.7518547618980741,0.837665032712619,0.35983999646262926,0.2713697941390661,-0.04237989884272554,0.6655800443025545,0.2713697941390661,-0.2705751034304403,1.007923945841884,1.5493709586917743,0.44780670716336934,0.35983999646262926,0.22694294684786878,-0.04237989884272554,1.2182725531206917,0.5788326555578377,0.09288087174021684,0.5352790715213577,0.7087759672510602,0.22694294684786878,0.9655270061034027,1.631137115186846,-0.31664072016034606
3,216
Amyloid beta metabolic process
9
11
2.46498
0.013702
Q13492,P14735,O95197,Q13526,Q13464,P42574,P27695,O75116,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
921,1031,7,591,757,703,147,572,333
572,7,1030,1031,147,703,1716,757,921,591,333
0.7948174485841241,3.5618213976734334,0.44780670716336934,0.44780670716336934,1.4672078084816735,0.7087759672510602,-0.04237989884272554,0.6655800443025545,0.5352790715213577,0.7948174485841241,1.0923878797824702
3,216
Protease
30
85
2.464844
0.013707
P54578,P42785,O14773,Q9HB40,Q8TCT9,P17655,Q9NY33,Q9H3G5,Q9Y4P1,Q6GQQ9,Q7L266,Q99497,Q14674,Q9Y5K5,O75844,Q86TI2,Q9H8M7,P55786,P42575,Q13867,Q92905,Q96BN8,P50579,P55212,Q9UPT9,Q9NZ08,Q96FW1,P48147,Q96FZ2,Q96RU2
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
249,6,377,156,19,384,561,27,567,293,550,164,423,336,62,196,479,86,85,214,363,365,461,93,111,245,107,345,260,132
1423,1296,377,2654,1022,2519,62,1871,960,1303,1098,1306,965,1818,2622,1031,384,638,1038,3106,971,2777,2898,703,85,6,854,345,461,977,2972,1666,913,249,535,93,86,2846,3214,1500,214,423,1400,1838,1885,1455,1334,819,293,550,196,601,3126,19,1946,363,1276,1742,365,107,260,1353,1684,132,2822,723,164,2337,1686,27,943,2937,479,156,1800,831,2020,561,245,3090,111,1594,567,1866,336
0.18238666517970953,0.2713697941390661,1.007923945841884,-0.8812303292626974,0.44780670716336934,-0.7379672099364472,1.8338555224412796,-0.17887471357436416,0.4916041220297551,0.2713697941390661,0.40388571004367557,0.2713697941390661,0.4916041220297551,-0.1332370713235067,-0.8333129569784509,0.44780670716336934,1.007923945841884,0.7518547618980741,0.44780670716336934,-1.7227710841237278,0.4916041220297551,-1.0259824528918617,-1.2213904611668245,0.7087759672510602,1.7125124116396768,3.598463949293977,0.5788326555578377,1.0502105964224744,0.9230188420539016,0.4916041220297551,-1.369821392742899,0.0028423592723265142,0.5352790715213577,1.2182725531206917,0.837665032712619,1.671873243824585,1.7125124116396768,-1.1233362600271486,-7.199832433182382,0.13769972233839525,1.301665163375922,0.9655270061034027,0.22694294684786878,-0.1332370713235067,-0.17887471357436416,0.18238666517970953,0.2713697941390661,0.6222659574604167,1.1344567049048861,0.837665032712619,1.3432048961451049,0.7948174485841241,-1.8254002143947679,2.5447719062106122,-0.22465358348725983,1.0502105964224744,0.31566841450154726,-0.04237989884272554,1.0502105964224744,1.631137115186846,1.2182725531206917,0.2713697941390661,0.0028423592723265142,1.5493709586917743,-1.0745728164819957,0.7087759672510602,1.4259753991464208,-0.5491826755969934,0.0028423592723265142,2.3501300710324777,0.5352790715213577,-1.2706853562868108,0.9230188420539016,1.4672078084816735,-0.0877392581795479,0.6222659574604167,-0.2705751034304403,0.837665032712619,1.2600213316709783,-1.620952575855485,1.631137115186846,0.09288087174021684,0.837665032712619,-0.1332370713235067,1.0923878797824702
3,216
Importin-beta, N-terminal domain [IPR001494]
9
14
2.46205
0.013815
O15397,P55060,Q9UI26,Q9HAV4,Q8TEX9,O43592,Q96P70,O00410,O95373
Sequence
InterPro Domain
interpro_domain
304,644,833,612,512,226,326,732,206
732,786,1159,304,226,206,644,1451,512,1275,326,612,833,1013
0.6655800443025545,0.6222659574604167,0.35983999646262926,1.0923878797824702,1.2600213316709783,1.301665163375922,0.7518547618980741,0.18238666517970953,0.880398505056007,0.31566841450154726,1.0923878797824702,0.7948174485841241,0.6222659574604167,0.4916041220297551
3,216
Toll like receptor tlr1 tlr2 cascade
9
16
2.460283
0.013883
Q13404,P51452,Q02750,P63208,P28482,Q13616,P30154,P30153,P09429
Processes and pathways
Reactome Pathways
msigdb_reactome
160,642,752,159,796,540,268,453,739
1298,739,796,453,268,642,1495,159,752,160,540,1507,1568,865,1931,2447
0.2713697941390661,0.6655800443025545,0.6222659574604167,0.9230188420539016,1.1764179680733708,0.7518547618980741,0.13769972233839525,1.4259753991464208,0.6655800443025545,1.4259753991464208,0.837665032712619,0.13769972233839525,0.09288087174021684,0.5788326555578377,-0.22465358348725983,-0.6432616792979482
3,216
Regulation of ubiquitin protein ligase activity
7
13
2.459043
0.013931
P63208,P60866,P62081,O00429,Q96GX5,P62841,P46777
Processes and pathways
GO Biological process
msigdb_gobp
159,464,75,443,120,22,704
443,1165,704,1979,464,803,75,1497,22,1441,159,2043,120
0.9230188420539016,0.35983999646262926,0.7087759672510602,-0.2705751034304403,0.9230188420539016,0.6222659574604167,1.753055360618528,0.13769972233839525,2.428239255449916,0.18238666517970953,1.4259753991464208,-0.31664072016034606,1.5903032740149434
3,216
Protein monoubiquitination
11
29
2.455764
0.014059
Q9NZJ0,P63208,Q5W0B1,Q9UBV8,Q99816,Q5VTB9,Q8TDB6,P62877,Q13616,Q86UK7,Q9C0C9
Processes and pathways
GO Biological process
msigdb_gobp
134,159,77,223,15,316,18,418,540,361,331
842,1701,1823,418,159,540,1559,1329,922,1453,316,866,77,2541,2217,2543,1197,600,361,2546,1344,18,2176,15,3035,331,2886,134,223
0.5788326555578377,-0.04237989884272554,-0.1332370713235067,0.9655270061034027,1.4259753991464208,0.837665032712619,0.09288087174021684,0.2713697941390661,0.5352790715213577,0.18238666517970953,1.0923878797824702,0.5788326555578377,1.753055360618528,-0.7379672099364472,-0.45571699704574653,-0.7379672099364472,0.35983999646262926,0.7948174485841241,1.0502105964224744,-0.7379672099364472,0.2713697941390661,2.583450148616519,-0.40921015652470366,2.62204635312281,-1.4697004768647024,1.0923878797824702,-1.1722747921416414,1.5493709586917743,1.301665163375922
3,216
Nucleophile aminohydrolases, N-terminal [IPR029055]
15
18
2.455426
0.014072
P25787,Q7L266,P28074,Q06210,P49720,P60900,P49721,P25788,P08243,Q06203,P25786,Q99436,P25789,P28072,P28066
Sequence
InterPro Superfamily
interpro_homologous_superfamily
82,550,1038,588,189,1122,39,637,1101,1052,794,723,208,638,1037
2517,1101,1175,794,82,637,208,1037,1825,638,1038,189,39,1122,1052,588,550,723
-0.7379672099364472,0.40388571004367557,0.35983999646262926,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,1.3432048961451049,2.1533494389689003,0.40388571004367557,0.44780670716336934,0.7948174485841241,0.837665032712619,0.7087759672510602
3,216
Abnormal reticulocyte morphology
6
31
2.455335
0.014075
P42766,Q15437,P62857,P62081,P62899,P62847
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
4,105,104,75,48,53
2462,1027,1100,1308,1971,1612,2664,2776,2474,2778,4,704,2808,1114,1250,464,1980,1391,75,585,1496,53,127,104,48,1441,2925,2156,105,511,1364
-0.6905352848819015,0.44780670716336934,0.40388571004367557,0.2713697941390661,-0.2705751034304403,0.04792884656143651,-0.8812303292626974,-1.0259824528918617,-0.6905352848819015,-1.0259824528918617,3.707979800175326,0.7087759672510602,-1.0745728164819957,0.40388571004367557,0.31566841450154726,0.9230188420539016,-0.2705751034304403,0.22694294684786878,1.753055360618528,0.7948174485841241,0.13769972233839525,1.9543521336080658,1.5493709586917743,1.631137115186846,2.0342222402293983,0.18238666517970953,-1.2706853562868108,-0.40921015652470366,1.631137115186846,0.880398505056007,0.2713697941390661
3,216
Eukaryotic translation initiation
31
101
2.449926
0.014289
Q9UBQ5,P62854,P42766,P62750,P62753,P06730,P62841,P62910,P46778,P15880,P63220,Q14152,P46782,P62899,P62847,P61513,Q9Y3U8,O75821,P60866,P84098,P62081,P25398,P55010,P49770,Q13144,P62857,P62244,Q7L2H7,Q04637,P62269,P05388
Processes and pathways
Reactome Pathways
msigdb_reactome
408,127,4,392,270,630,22,150,148,635,647,713,416,48,53,708,621,687,464,76,75,699,211,458,234,104,585,662,505,503,113
1423,1754,1019,1425,687,1375,1229,3128,113,630,1308,1610,2253,635,2664,2086,904,1174,1034,2310,699,744,906,1540,1826,1828,2360,2778,1713,2574,1112,4,1181,704,148,1434,1385,416,2808,1664,1544,458,1116,211,1668,1547,1121,1390,464,978,1980,1391,708,803,75,1187,585,1981,1392,1326,503,1496,1620,804,1393,1257,392,270,1497,22,53,1498,127,104,1499,858,48,1050,150,1441,1125,1927,647,1189,1879,76,2715,1672,505,2156,234,1504,713,983,1448,662,1359,408,2184,1089,621
0.18238666517970953,-0.0877392581795479,0.44780670716336934,0.18238666517970953,0.7087759672510602,0.22694294684786878,0.31566841450154726,-1.8770253627023152,1.5903032740149434,0.7518547618980741,0.2713697941390661,0.04792884656143651,-0.5023739774096585,0.7518547618980741,-0.8812303292626974,-0.3628519054147641,0.5352790715213577,0.35983999646262926,0.44780670716336934,-0.5491826755969934,0.7087759672510602,0.6655800443025545,0.5352790715213577,0.09288087174021684,-0.1332370713235067,-0.1332370713235067,-0.5961446978316173,-1.0259824528918617,-0.04237989884272554,-0.7855591810728211,0.40388571004367557,3.707979800175326,0.35983999646262926,0.7087759672510602,1.4672078084816735,0.18238666517970953,0.22694294684786878,0.9655270061034027,-1.0745728164819957,0.0028423592723265142,0.09288087174021684,0.9230188420539016,0.40388571004367557,1.301665163375922,0.0028423592723265142,0.09288087174021684,0.40388571004367557,0.22694294684786878,0.9230188420539016,0.4916041220297551,-0.2705751034304403,0.22694294684786878,0.7087759672510602,0.6222659574604167,1.753055360618528,0.35983999646262926,0.7948174485841241,-0.2705751034304403,0.22694294684786878,0.2713697941390661,0.880398505056007,0.13769972233839525,0.04792884656143651,0.6222659574604167,0.22694294684786878,0.31566841450154726,1.007923945841884,1.1764179680733708,0.13769972233839525,2.428239255449916,1.9543521336080658,0.13769972233839525,1.5493709586917743,1.631137115186846,0.13769972233839525,0.5788326555578377,2.0342222402293983,0.44780670716336934,1.4672078084816735,0.18238666517970953,0.40388571004367557,-0.22465358348725983,0.7518547618980741,0.35983999646262926,-0.17887471357436416,1.753055360618528,-0.9293131233315839,0.0028423592723265142,0.880398505056007,-0.40921015652470366,1.2600213316709783,0.13769972233839525,0.7087759672510602,0.4916041220297551,0.18238666517970953,0.7518547618980741,0.2713697941390661,1.007923945841884,-0.40921015652470366,0.44780670716336934,0.7948174485841241
3,216
Abc family proteins mediated transport
38
50
2.449393
0.01431
P41091,Q99460,O00232,P25788,Q9UNM6,P28072,P35998,P49721,O43242,P40855,O00231,P61289,P25786,P20042,Q99436,P51665,P20618,P43686,P62191,P28066,P28074,P49720,Q9UL46,Q15008,O00233,P55036,P25787,P25789,O75832,P60900,Q13200,P62333,Q92530,P62195,P17980,P05198,Q06323,P55072
Processes and pathways
Reactome Pathways
msigdb_reactome
1112,1074,376,637,566,638,639,39,1161,532,1017,915,794,1174,723,1048,1175,1046,1186,1037,1038,189,90,984,204,212,82,208,956,1122,981,586,513,584,1233,1229,354,1119
1017,376,204,1296,2517,1161,2656,2658,956,2308,1229,1233,1174,1175,794,82,637,208,1037,1825,638,1038,3000,639,532,1112,1046,1249,189,39,1048,212,1119,1122,915,1186,584,586,354,981,2373,984,1407,513,723,1074,2014,1586,90,566
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,-0.7379672099364472,0.35983999646262926,-0.8812303292626974,-0.8812303292626974,0.4916041220297551,-0.5491826755969934,0.31566841450154726,0.31566841450154726,0.35983999646262926,0.35983999646262926,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,-1.4196669272842548,0.7518547618980741,0.837665032712619,0.40388571004367557,0.44780670716336934,0.31566841450154726,1.3432048961451049,2.1533494389689003,0.44780670716336934,1.301665163375922,0.40388571004367557,0.40388571004367557,0.5352790715213577,0.35983999646262926,0.7948174485841241,0.7948174485841241,1.0502105964224744,0.4916041220297551,-0.5961446978316173,0.4916041220297551,0.22694294684786878,0.880398505056007,0.7087759672510602,0.44780670716336934,-0.2705751034304403,0.09288087174021684,1.7125124116396768,0.837665032712619
3,216
Signaling by robo receptors
83
142
2.446781
0.014414
P15170,P42766,Q99460,Q9UNM6,P62841,P49721,P23396,O00231,P62899,P62847,P51665,P43686,P62906,P28066,P28074,Q9Y3U8,P84098,P62081,Q9UL46,P25787,P60900,P62917,P62333,P62857,P62244,P62195,P50914,P05388,P62854,P25788,P07737,P62910,P46778,P15880,P28072,P35998,P63220,P83731,O43242,Q99436,P20618,P46776,P62191,P62241,P61513,P49720,O75122,P25398,O00233,P55036,P46777,P25789,Q9Y5S9,P26373,P62495,P62753,Q9HAU5,P25786,P61927,P62280,Q15369,Q06323,P62888,O00232,P62750,O14786,P18621,P27635,P61289,P46782,P62877,Q15370,P60866,Q15008,P12931,O75832,Q13200,Q92530,P61247,P16333,Q04637,P62269,Q7Z460
Processes and pathways
Reactome Pathways
msigdb_reactome
496,4,1074,566,22,39,1034,1017,48,53,1048,1046,1050,1037,1038,621,76,75,90,82,1122,1125,586,104,585,584,1116,113,127,637,631,150,148,635,638,639,647,1189,1161,723,1175,1181,1186,1187,708,189,686,699,204,212,704,208,781,744,751,270,829,794,803,804,314,354,858,376,392,893,904,906,915,416,418,424,464,984,451,956,981,513,978,969,505,503,1065
1017,376,204,1296,893,2517,1161,686,956,1703,2034,3128,113,631,1308,1610,2253,451,1707,496,635,969,1485,1233,2664,2086,904,1175,1034,699,794,82,637,208,744,906,1037,1825,638,1038,1540,1826,1432,1828,639,2360,2807,2778,1713,2574,4,1046,1181,704,148,1434,1385,416,2808,1664,1249,1544,189,39,1116,1048,2093,212,464,1122,1325,978,915,1980,1391,708,1185,803,75,1186,584,1187,585,1981,1392,1326,503,1496,1620,804,586,1393,751,1257,392,270,1497,22,53,1498,127,104,1499,418,858,48,1050,150,1441,1125,1836,1927,647,1189,1879,76,1880,2715,1672,505,354,2156,1725,1726,981,1262,2373,984,2536,314,424,1993,1065,1513,513,723,1074,829,90,566,621,781
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,0.5352790715213577,-0.7379672099364472,0.35983999646262926,0.7087759672510602,0.4916041220297551,-0.04237989884272554,-0.31664072016034606,-1.8770253627023152,1.5903032740149434,0.7518547618980741,0.2713697941390661,0.04792884656143651,-0.5023739774096585,0.9230188420539016,-0.04237989884272554,0.880398505056007,0.7518547618980741,0.4916041220297551,0.13769972233839525,0.31566841450154726,-0.8812303292626974,-0.3628519054147641,0.5352790715213577,0.35983999646262926,0.44780670716336934,0.7087759672510602,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.6655800443025545,0.5352790715213577,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,0.09288087174021684,-0.1332370713235067,0.18238666517970953,-0.1332370713235067,0.7518547618980741,-0.5961446978316173,-1.0745728164819957,-1.0259824528918617,-0.04237989884272554,-0.7855591810728211,3.707979800175326,0.44780670716336934,0.35983999646262926,0.7087759672510602,1.4672078084816735,0.18238666517970953,0.22694294684786878,0.9655270061034027,-1.0745728164819957,0.0028423592723265142,0.31566841450154726,0.09288087174021684,1.3432048961451049,2.1533494389689003,0.40388571004367557,0.44780670716336934,-0.3628519054147641,1.301665163375922,0.9230188420539016,0.40388571004367557,0.2713697941390661,0.4916041220297551,0.5352790715213577,-0.2705751034304403,0.22694294684786878,0.7087759672510602,0.35983999646262926,0.6222659574604167,1.753055360618528,0.35983999646262926,0.7948174485841241,0.35983999646262926,0.7948174485841241,-0.2705751034304403,0.22694294684786878,0.2713697941390661,0.880398505056007,0.13769972233839525,0.04792884656143651,0.6222659574604167,0.7948174485841241,0.22694294684786878,0.6655800443025545,0.31566841450154726,1.007923945841884,1.1764179680733708,0.13769972233839525,2.428239255449916,1.9543521336080658,0.13769972233839525,1.5493709586917743,1.631137115186846,0.13769972233839525,0.9655270061034027,0.5788326555578377,2.0342222402293983,0.44780670716336934,1.4672078084816735,0.18238666517970953,0.40388571004367557,-0.1332370713235067,-0.22465358348725983,0.7518547618980741,0.35983999646262926,-0.17887471357436416,1.753055360618528,-0.17887471357436416,-0.9293131233315839,0.0028423592723265142,0.880398505056007,1.0502105964224744,-0.40921015652470366,-0.04237989884272554,-0.04237989884272554,0.4916041220297551,0.31566841450154726,-0.5961446978316173,0.4916041220297551,-0.7379672099364472,1.0923878797824702,0.9655270061034027,-0.2705751034304403,0.44780670716336934,0.13769972233839525,0.880398505056007,0.7087759672510602,0.44780670716336934,0.6222659574604167,1.7125124116396768,0.837665032712619,0.7948174485841241,0.6655800443025545
3,216
Regulation of proteasomal ubiquitin dependent protein catabolic process
32
52
2.440246
0.014677
P54578,P48506,Q9BW61,Q9UL15,Q9Y4X5,P24941,Q9UNE7,Q99497,Q8NEZ5,Q9ULT8,Q9NZL4,O14980,P78559,O15294,O14965,Q96KB5,P08238,P62877,O15372,P63244,Q15370,Q9Y5K5,Q9C0D3,O75925,O75832,Q86UE8,O14908,P46379,Q92990,P10398,P45974,P55072
Processes and pathways
GO Biological process
msigdb_gobp
249,1114,139,142,1091,385,565,164,294,1217,40,1159,289,1018,787,178,1168,418,1019,537,424,336,476,957,956,763,840,344,515,1102,854,1119
840,787,1159,1018,1019,1532,956,957,2471,1228,1165,2352,1168,1817,1102,385,854,344,1114,1833,2478,1979,249,2263,1119,1721,418,1441,537,289,2429,2586,424,763,2053,294,2685,515,1742,1743,178,164,139,476,1954,40,142,1217,565,1091,2137,336
0.5788326555578377,0.6222659574604167,0.35983999646262926,0.44780670716336934,0.44780670716336934,0.09288087174021684,0.4916041220297551,0.4916041220297551,-0.6905352848819015,0.31566841450154726,0.35983999646262926,-0.5961446978316173,0.35983999646262926,-0.1332370713235067,0.40388571004367557,1.007923945841884,0.5788326555578377,1.0502105964224744,0.40388571004367557,-0.1332370713235067,-0.6905352848819015,-0.2705751034304403,1.2182725531206917,-0.5023739774096585,0.40388571004367557,-0.04237989884272554,0.9655270061034027,0.18238666517970953,0.837665032712619,1.1344567049048861,-0.6432616792979482,-0.7855591810728211,0.9655270061034027,0.6655800443025545,-0.31664072016034606,1.1344567049048861,-0.8812303292626974,0.880398505056007,-0.04237989884272554,-0.04237989884272554,1.3846413663706636,1.4259753991464208,1.5083393975097876,0.9230188420539016,-0.22465358348725983,2.1533494389689003,1.5083393975097876,0.35983999646262926,0.837665032712619,0.44780670716336934,-0.3628519054147641,1.0923878797824702
3,216
Microtubule polymerization or depolymerization
23
43
2.437495
0.014789
Q08379,Q15691,P29372,Q9NVX0,P78559,Q8IX90,Q14008,Q96P70,Q15555,Q92597,O00139,Q02790,Q9Y295,O43670,O75122,Q9P1Y5,Q9BTW9,P46821,Q92974,Q13526,P04350,Q96S59,Q7Z460
Processes and pathways
GO Biological process
msigdb_gobp
754,653,137,1082,289,176,541,326,173,996,783,807,729,305,686,617,880,209,514,591,103,1072,1065
783,1753,305,686,103,1817,1231,1034,137,2205,1542,209,1492,1836,289,807,754,591,541,1191,2270,173,653,1993,2274,1934,1065,176,1944,996,514,1277,326,1072,1893,1470,880,1082,2339,617,1420,2889,729
0.6222659574604167,-0.0877392581795479,1.0923878797824702,0.7087759672510602,1.631137115186846,-0.1332370713235067,0.31566841450154726,0.44780670716336934,1.5083393975097876,-0.45571699704574653,0.09288087174021684,1.301665163375922,0.13769972233839525,-0.1332370713235067,1.1344567049048861,0.6222659574604167,0.6655800443025545,0.7948174485841241,0.837665032712619,0.35983999646262926,-0.5023739774096585,1.3846413663706636,0.7518547618980741,-0.2705751034304403,-0.5023739774096585,-0.22465358348725983,0.44780670716336934,1.3846413663706636,-0.22465358348725983,0.4916041220297551,0.880398505056007,0.31566841450154726,1.0923878797824702,0.44780670716336934,-0.17887471357436416,0.18238666517970953,0.5788326555578377,0.44780670716336934,-0.5491826755969934,0.7948174485841241,0.22694294684786878,-1.1722747921416414,0.7087759672510602
3,216
Antigen processing ubiquitination proteasome degradation
59
102
2.430552
0.015076
Q9GZZ9,Q05086,Q99460,O00232,Q15386,P25788,Q8TDB6,Q9NXK8,Q9UNM6,P61081,Q9UNE7,P28072,P35998,Q8NEZ5,Q13404,P49721,P63208,Q13309,O00231,P61289,P62877,Q13616,P25786,P51665,Q99436,P43686,Q7Z6Z7,Q9C0C9,P28066,Q15370,Q7Z7E8,P49720,Q8IWV7,Q9Y4B6,O95352,Q15369,Q9UII4,Q5VTB9,P68036,Q9UL46,P55786,Q13867,O00233,P55036,P25787,Q8TBC4,P25789,Q15008,O75832,A0AVT1,Q13200,P62333,Q92530,P62195,Q92990,P52888,P29144,Q06323,Q93034
Processes and pathways
Reactome Pathways
msigdb_reactome
672,753,1074,376,651,637,18,1084,566,390,565,638,639,294,160,39,159,290,1017,915,418,540,794,1048,723,1046,600,331,1037,424,319,189,873,1015,307,314,618,316,465,90,86,214,204,212,82,362,208,984,956,837,981,586,513,584,515,977,971,354,933
837,1017,376,204,1296,2517,1161,956,1915,2471,307,1228,2869,1233,1175,1316,794,82,637,208,1037,1825,638,1038,971,2418,639,1046,1249,189,39,1048,977,212,86,2365,1122,390,1721,1495,915,1186,584,586,418,159,465,753,354,2848,981,290,160,540,1262,1559,214,1331,2586,2212,2373,2678,984,1780,314,424,651,3209,1335,1194,316,1936,1197,600,319,873,294,362,18,513,515,933,2498,2857,723,1074,331,672,2126,1084,618,2610,2185,1806,1807,1420,90,1217,565,566,1422,1015
0.5788326555578377,0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,-0.7379672099364472,0.35983999646262926,0.4916041220297551,-0.22465358348725983,-0.6905352848819015,1.0923878797824702,0.31566841450154726,-1.1722747921416414,0.31566841450154726,0.35983999646262926,0.2713697941390661,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,0.4916041220297551,-0.6432616792979482,0.7518547618980741,0.44780670716336934,0.31566841450154726,1.3432048961451049,2.1533494389689003,0.44780670716336934,0.4916041220297551,1.301665163375922,1.7125124116396768,-0.5961446978316173,0.40388571004367557,1.007923945841884,-0.04237989884272554,0.13769972233839525,0.5352790715213577,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.9655270061034027,1.4259753991464208,0.9230188420539016,0.6655800443025545,1.0502105964224744,-1.1233362600271486,0.4916041220297551,1.1344567049048861,1.4259753991464208,0.837665032712619,0.31566841450154726,0.09288087174021684,1.301665163375922,0.2713697941390661,-0.7855591810728211,-0.45571699704574653,-0.5961446978316173,-0.8812303292626974,0.4916041220297551,-0.0877392581795479,1.0923878797824702,0.9655270061034027,0.7518547618980741,-3.887194361900442,0.2713697941390661,0.35983999646262926,1.0923878797824702,-0.22465358348725983,0.35983999646262926,0.7948174485841241,1.0923878797824702,0.5788326555578377,1.1344567049048861,1.0502105964224744,2.583450148616519,0.880398505056007,0.880398505056007,0.5352790715213577,-0.6905352848819015,-1.1233362600271486,0.7087759672510602,0.44780670716336934,1.0923878797824702,0.7518547618980741,-0.3628519054147641,0.44780670716336934,0.7948174485841241,-0.7855591810728211,-0.40921015652470366,-0.0877392581795479,-0.0877392581795479,0.22694294684786878,1.7125124116396768,0.35983999646262926,0.837665032712619,0.837665032712619,0.22694294684786878,0.4916041220297551
3,216
Limbic system development
6
21
2.424302
0.015338
Q6PIY7,P21359,P46109,Q13144,P23634,P27695
Processes and pathways
GO Biological process
msigdb_gobp
95,68,69,234,136,147
837,893,849,68,136,147,703,974,69,1833,2713,1440,251,860,2714,234,1328,1566,2215,95,2395
0.5788326555578377,0.5352790715213577,0.5788326555578377,1.7935028231987427,1.5083393975097876,1.4672078084816735,0.7087759672510602,0.4916041220297551,1.7935028231987427,-0.1332370713235067,-0.9293131233315839,0.18238666517970953,1.2182725531206917,0.5788326555578377,-0.9293131233315839,1.2600213316709783,0.2713697941390661,0.09288087174021684,-0.45571699704574653,1.671873243824585,-0.5961446978316173
3,216
Female sex differentiation
9
18
2.419281
0.015551
O75874,Q13144,O95470,P24468,Q12948,P42575,P42574,P12931,P49770
Processes and pathways
GO Biological process
msigdb_gobp
738,234,382,698,232,85,703,451,458
738,1703,382,451,698,972,1977,703,85,458,2627,753,232,234,1556,1350,1644,2184
0.6655800443025545,-0.04237989884272554,1.007923945841884,0.9230188420539016,0.7087759672510602,0.4916041220297551,-0.2705751034304403,0.7087759672510602,1.7125124116396768,0.9230188420539016,-0.8333129569784509,0.6655800443025545,1.2600213316709783,1.2600213316709783,0.09288087174021684,0.2713697941390661,0.04792884656143651,-0.40921015652470366
3,216
Toll like receptor cascades
12
25
2.414781
0.015745
Q13404,P51452,Q02750,P63208,Q6SZW1,P28482,P09429,P30154,Q13616,Q06124,P30153,Q13546
Processes and pathways
Reactome Pathways
msigdb_reactome
160,642,752,159,138,796,739,268,540,353,453,254
1298,1306,739,2871,796,453,268,1491,642,1495,159,752,353,160,254,540,1507,2162,1568,865,1931,138,1280,2447,1749
0.2713697941390661,0.2713697941390661,0.6655800443025545,-1.1722747921416414,0.6222659574604167,0.9230188420539016,1.1764179680733708,0.13769972233839525,0.7518547618980741,0.13769972233839525,1.4259753991464208,0.6655800443025545,1.0502105964224744,1.4259753991464208,1.2182725531206917,0.837665032712619,0.13769972233839525,-0.40921015652470366,0.09288087174021684,0.5788326555578377,-0.22465358348725983,1.5083393975097876,0.31566841450154726,-0.6432616792979482,-0.04237989884272554
3,216
Phase ii conjugation of compounds
15
32
2.413663
0.015793
Q8WUX2,O95340,Q16851,P21266,O43252,O75223,Q9HBK9,P78417,P14550,Q9UI30,P23526,P48637,O95861,Q99707,Q96IU4
Processes and pathways
Reactome Pathways
msigdb_reactome
197,492,988,187,337,339,278,43,846,60,851,855,448,825,199
2027,337,1370,1163,339,492,448,1819,846,187,1315,851,1177,1318,1114,1248,855,43,988,1845,197,199,1684,825,2792,2178,278,1801,1011,60,2457,1529
-0.31664072016034606,1.0502105964224744,0.22694294684786878,0.35983999646262926,1.0502105964224744,0.880398505056007,0.9230188420539016,-0.1332370713235067,0.5788326555578377,1.3432048961451049,0.2713697941390661,0.5788326555578377,0.35983999646262926,0.2713697941390661,0.40388571004367557,0.31566841450154726,0.5788326555578377,2.07402103934834,0.4916041220297551,-0.1332370713235067,1.3432048961451049,1.3432048961451049,0.0028423592723265142,0.6222659574604167,-1.0259824528918617,-0.40921015652470366,1.1764179680733708,-0.0877392581795479,0.4916041220297551,1.874114172198667,-0.6432616792979482,0.13769972233839525
3,216
Dna replication
18
31
2.411821
0.015873
P18858,P40937,P49736,P35250,P35249,P49643,Q14181,P49005,P27694,P33991,Q9NR33,P12004,O75792,P25205,P39748,P09884,P35244,Q15054
Processes and pathways
KEGG Pathways
msigdb_kegg
741,702,126,455,745,188,506,640,700,577,772,528,380,793,171,632,83,468
380,632,528,2525,741,793,700,1039,577,1241,1488,83,745,455,1489,171,702,1045,640,799,188,126,2094,3028,980,506,1450,468,772,2645,2862
1.007923945841884,0.7518547618980741,0.837665032712619,-0.7379672099364472,0.6655800443025545,0.6222659574604167,0.7087759672510602,0.44780670716336934,0.7948174485841241,0.31566841450154726,0.13769972233839525,1.7125124116396768,0.6655800443025545,0.9230188420539016,0.13769972233839525,1.3846413663706636,0.7087759672510602,0.44780670716336934,0.7518547618980741,0.6222659574604167,1.3432048961451049,1.5493709586917743,-0.3628519054147641,-1.4697004768647024,0.4916041220297551,0.880398505056007,0.18238666517970953,0.9230188420539016,0.6655800443025545,-0.8333129569784509,-1.1233362600271486
3,216
Purine nucleoside monophosphate biosynthetic process
12
15
2.391802
0.016766
P22102,Q01433,P22234,P12268,P30520,P07741,P11908,P00492,Q06203,P49915,P20839,P31939
Processes and pathways
GO Biological process
msigdb_gobp
742,311,1107,495,500,1099,229,628,1052,210,636,576
1160,628,1099,229,495,636,742,1107,500,1487,576,210,1324,311,1052
0.35983999646262926,0.7518547618980741,0.40388571004367557,1.2600213316709783,0.880398505056007,0.7518547618980741,0.6655800443025545,0.40388571004367557,0.880398505056007,0.13769972233839525,0.7948174485841241,1.301665163375922,0.2713697941390661,1.0923878797824702,0.44780670716336934
3,216
Stress activated protein kinase signaling cascade
8
35
2.390525
0.016824
O75844,P46109,P29372,Q53EL6,Q99956,Q96KB5,Q99873,Q13546
Processes and pathways
GO Biological process
msigdb_gobp
62,69,137,13,275,178,200,254
1753,1816,1964,62,2409,1428,961,1536,739,1032,1918,796,137,1040,2668,974,69,1766,1250,642,1325,1185,752,1882,809,254,1931,13,363,2498,178,200,275,2724,885
-0.0877392581795479,-0.1332370713235067,-0.2705751034304403,1.8338555224412796,-0.6432616792979482,0.18238666517970953,0.4916041220297551,0.09288087174021684,0.6655800443025545,0.44780670716336934,-0.22465358348725983,0.6222659574604167,1.5083393975097876,0.44780670716336934,-0.8812303292626974,0.4916041220297551,1.7935028231987427,-0.0877392581795479,0.31566841450154726,0.7518547618980741,0.2713697941390661,0.35983999646262926,0.6655800443025545,-0.17887471357436416,0.6222659574604167,1.2182725531206917,-0.22465358348725983,2.889968945701032,1.0502105964224744,-0.6905352848819015,1.3846413663706636,1.3432048961451049,1.1764179680733708,-0.9293131233315839,0.5788326555578377
3,216
Tgf beta signaling pathway
7
11
2.390203
0.016839
P63208,Q13464,P30154,Q13616,P62877,O75116,P30153
Processes and pathways
KEGG Pathways
msigdb_kegg
159,757,268,540,418,572,453
572,796,453,268,1185,418,159,757,1556,540,1269
0.7948174485841241,0.6222659574604167,0.9230188420539016,1.1764179680733708,0.35983999646262926,0.9655270061034027,1.4259753991464208,0.6655800443025545,0.09288087174021684,0.837665032712619,0.31566841450154726
3,216
Copi mediated anterograde transport
25
55
2.385933
0.017036
P24390,Q08379,P47756,O43237,Q14204,O15155,Q13561,P84085,O75935,O60763,Q9BUF5,Q96FJ2,Q12893,Q96JB2,P47755,O14579,P68371,Q13885,P53618,Q8N6T3,Q9NZ32,Q14789,P04350,Q01082,Q92538
Processes and pathways
Reactome Pathways
msigdb_reactome
5,754,746,263,815,378,152,271,146,625,434,295,649,37,42,785,419,422,802,606,616,508,103,861,401
785,378,1020,263,625,146,103,3211,1710,5,1178,2423,42,746,1246,1716,1923,802,1546,1773,1619,2580,1439,1188,419,271,861,754,649,1054,1056,2481,152,1929,422,1191,815,508,924,2329,606,401,295,37,1951,434,1852,1582,616,1646,1014,1291,2243,1960,1366
0.6222659574604167,1.007923945841884,0.44780670716336934,1.1764179680733708,0.7518547618980741,1.4672078084816735,1.631137115186846,-4.43459238328647,-0.04237989884272554,3.6350375895465477,0.35983999646262926,-0.6432616792979482,2.07402103934834,0.6655800443025545,0.31566841450154726,-0.04237989884272554,-0.22465358348725983,0.6222659574604167,0.09288087174021684,-0.0877392581795479,0.04792884656143651,-0.7855591810728211,0.18238666517970953,0.35983999646262926,0.9655270061034027,1.1764179680733708,0.5788326555578377,0.6655800443025545,0.7518547618980741,0.44780670716336934,0.44780670716336934,-0.6905352848819015,1.4672078084816735,-0.22465358348725983,0.9655270061034027,0.35983999646262926,0.6222659574604167,0.880398505056007,0.5352790715213577,-0.5491826755969934,0.7948174485841241,1.007923945841884,1.1344567049048861,2.1928803390588034,-0.22465358348725983,0.9655270061034027,-0.1332370713235067,0.09288087174021684,0.7948174485841241,0.04792884656143651,0.4916041220297551,0.31566841450154726,-0.45571699704574653,-0.22465358348725983,0.2713697941390661
3,216
Activation of the pre replicative complex
11
21
2.383768
0.017136
P49736,Q14181,P49643,P27694,Q9NR33,P25205,P09884,P35244,P24941,O43929,P33991
Processes and pathways
Reactome Pathways
msigdb_reactome
126,506,188,700,772,793,632,83,385,144,577
1654,144,632,2525,385,793,700,577,1241,1488,83,799,188,126,2094,980,506,1450,772,2645,1085
0.0028423592723265142,1.4672078084816735,0.7518547618980741,-0.7379672099364472,1.007923945841884,0.6222659574604167,0.7087759672510602,0.7948174485841241,0.31566841450154726,0.13769972233839525,1.7125124116396768,0.6222659574604167,1.3432048961451049,1.5493709586917743,-0.3628519054147641,0.4916041220297551,0.880398505056007,0.18238666517970953,0.6655800443025545,-0.8333129569784509,0.44780670716336934
3,216
Cytoprotection by hmox1
25
68
2.367024
0.017932
P30519,O00232,P25788,Q8TCT9,Q9UNM6,P28072,P35998,P49721,P63208,Q13309,Q86X55,P62877,Q13616,P49720,P19784,Q9UL46,O00233,P55036,P25787,P25789,P67870,P62333,Q92530,P62195,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
9,376,637,19,566,638,639,39,159,290,714,418,540,189,186,90,204,212,82,208,587,586,513,584,354
1017,376,204,2515,1296,2517,1161,1602,1964,956,2079,2251,1029,2950,2144,2623,1233,186,1175,2417,794,82,637,208,1037,1825,638,1038,3067,9,639,1615,2420,1046,1249,189,39,1048,1436,212,1122,915,1186,584,586,418,159,587,2925,354,981,290,540,1559,2586,2373,984,2214,714,19,513,2821,723,1074,3058,90,566,2702
0.44780670716336934,1.007923945841884,1.301665163375922,-0.7379672099364472,0.2713697941390661,-0.7379672099364472,0.35983999646262926,0.04792884656143651,-0.2705751034304403,0.4916041220297551,-0.3628519054147641,-0.5023739774096585,0.44780670716336934,-1.3201616086849464,-0.40921015652470366,-0.8333129569784509,0.31566841450154726,1.3432048961451049,0.35983999646262926,-0.6432616792979482,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,-1.5703409161105824,3.191510823142953,0.7518547618980741,0.04792884656143651,-0.6432616792979482,0.44780670716336934,0.31566841450154726,1.3432048961451049,2.1533494389689003,0.44780670716336934,0.18238666517970953,1.301665163375922,0.40388571004367557,0.5352790715213577,0.35983999646262926,0.7948174485841241,0.7948174485841241,0.9655270061034027,1.4259753991464208,0.7948174485841241,-1.2706853562868108,1.0502105964224744,0.4916041220297551,1.1344567049048861,0.837665032712619,0.09288087174021684,-0.7855591810728211,-0.5961446978316173,0.4916041220297551,-0.45571699704574653,0.7087759672510602,2.5447719062106122,0.880398505056007,-1.0745728164819957,0.7087759672510602,0.44780670716336934,-1.5199243531109388,1.7125124116396768,0.837665032712619,-0.8812303292626974
3,216
Retinoblastoma gene in cancer
28
50
2.364011
0.018078
P14635,O14757,Q00534,P35249,P09884,P11802,P24941,Q14527,P06493,P26358,Q13309,P12004,P31350,Q16204,P25205,Q15054,P52701,P49642,P40937,O95239,Q9UNN5,P27694,P35244,P33991,O75446,P06400,Q07864,P09429
Processes and pathways
WikiPathways
msigdb_wp
740,246,251,745,632,633,385,650,899,530,290,528,414,543,793,468,800,799,702,688,619,700,83,577,954,341,980,739
246,954,1759,688,1534,2771,1609,341,899,739,632,2951,633,528,740,2525,1231,1238,385,793,530,970,700,414,1875,577,1488,83,745,702,1045,799,800,2094,1722,251,980,1503,290,1328,650,1450,2587,468,543,2821,2062,2019,619,2066
1.2182725531206917,0.4916041220297551,-0.0877392581795479,0.7087759672510602,0.09288087174021684,-1.0259824528918617,0.04792884656143651,1.0502105964224744,0.5352790715213577,0.6655800443025545,0.7518547618980741,-1.3201616086849464,0.7518547618980741,0.837665032712619,0.6655800443025545,-0.7379672099364472,0.31566841450154726,0.31566841450154726,1.007923945841884,0.6222659574604167,0.837665032712619,0.4916041220297551,0.7087759672510602,0.9655270061034027,-0.17887471357436416,0.7948174485841241,0.13769972233839525,1.7125124116396768,0.6655800443025545,0.7087759672510602,0.44780670716336934,0.6222659574604167,0.6222659574604167,-0.3628519054147641,-0.04237989884272554,1.2182725531206917,0.4916041220297551,0.13769972233839525,1.1344567049048861,0.2713697941390661,0.7518547618980741,0.18238666517970953,-0.7855591810728211,0.9230188420539016,0.837665032712619,-1.0745728164819957,-0.31664072016034606,-0.2705751034304403,0.7948174485841241,-0.31664072016034606
3,216
Synthesis of substrates in n glycan biosythesis
8
17
2.362539
0.01815
Q9NR45,Q9UJ70,Q16222,Q96EK6,O60547,P16278,O95394,O14772
Processes and pathways
Reactome Pathways
msigdb_reactome
614,182,315,274,73,452,170,570
570,73,2031,170,1818,452,797,588,315,1066,2282,274,1206,614,182,1695,2730
0.7948174485841241,1.753055360618528,-0.31664072016034606,1.3846413663706636,-0.1332370713235067,0.9230188420539016,0.6222659574604167,0.7948174485841241,1.0923878797824702,0.44780670716336934,-0.5023739774096585,1.1764179680733708,0.35983999646262926,0.7948174485841241,1.3846413663706636,0.0028423592723265142,-0.9293131233315839
3,216
Negative regulation of proteasomal ubiquitin dependent protein catabolic process
6
19
2.360699
0.018241
P54578,Q99497,Q9UL15,P78559,Q96KB5,Q9Y5K5
Processes and pathways
GO Biological process
msigdb_gobp
249,164,142,289,178,336
840,1018,1019,1532,1168,344,249,1441,289,2429,763,2053,2685,1742,1743,178,164,142,336
0.5788326555578377,0.44780670716336934,0.44780670716336934,0.09288087174021684,0.35983999646262926,1.0502105964224744,1.2182725531206917,0.18238666517970953,1.1344567049048861,-0.6432616792979482,0.6655800443025545,-0.31664072016034606,-0.8812303292626974,-0.04237989884272554,-0.04237989884272554,1.3846413663706636,1.4259753991464208,1.5083393975097876,1.0923878797824702
3,216
Development of primary female sexual characteristics
9
17
2.359541
0.018298
O75874,Q13144,O95470,P24468,Q12948,P42575,P42574,P12931,P49770
Processes and pathways
GO Biological process
msigdb_gobp
738,234,382,698,232,85,703,451,458
738,1703,382,451,698,972,1977,703,85,458,2627,753,232,234,1556,1350,2184
0.6655800443025545,-0.04237989884272554,1.007923945841884,0.9230188420539016,0.7087759672510602,0.4916041220297551,-0.2705751034304403,0.7087759672510602,1.7125124116396768,0.9230188420539016,-0.8333129569784509,0.6655800443025545,1.2600213316709783,1.2600213316709783,0.09288087174021684,0.2713697941390661,-0.40921015652470366
3,216
Cilium assembly
34
55
2.351194
0.018713
Q96CS2,Q15691,O60645,O94927,Q14204,Q13561,P07437,Q9NVX0,O75935,Q96KP1,Q9BUF5,P06493,Q96FJ2,Q9Y496,Q14203,P17987,P63167,P68371,Q8IW35,Q14008,Q13885,Q9H6D7,P50990,P48643,Q15154,Q9Y547,P30153,P78371,O00471,P43034,P04350,Q7Z460,Q92538,Q9BW83
Processes and pathways
Reactome Pathways
msigdb_reactome
934,653,490,626,815,152,267,1082,146,430,434,899,295,1220,1191,903,1188,419,175,541,422,332,706,705,1264,100,453,1127,838,974,103,1065,401,670
838,490,146,626,103,899,267,1307,1485,903,1710,453,3094,1542,974,705,1322,706,1252,1979,1775,1619,2672,2713,1188,419,1127,2097,2481,152,422,541,1191,815,1508,1264,653,1065,175,1575,2284,401,1275,934,295,430,434,670,2125,332,1901,1905,1082,1220,100
0.5788326555578377,0.880398505056007,1.4672078084816735,0.7518547618980741,1.631137115186846,0.5352790715213577,1.1764179680733708,0.2713697941390661,0.13769972233839525,0.5352790715213577,-0.04237989884272554,0.9230188420539016,-1.671761793740974,0.09288087174021684,0.4916041220297551,0.7087759672510602,0.2713697941390661,0.7087759672510602,0.31566841450154726,-0.2705751034304403,-0.0877392581795479,0.04792884656143651,-0.8812303292626974,-0.9293131233315839,0.35983999646262926,0.9655270061034027,0.40388571004367557,-0.3628519054147641,-0.6905352848819015,1.4672078084816735,0.9655270061034027,0.837665032712619,0.35983999646262926,0.6222659574604167,0.13769972233839525,0.31566841450154726,0.7518547618980741,0.44780670716336934,1.3846413663706636,0.09288087174021684,-0.5023739774096585,1.007923945841884,0.31566841450154726,0.5352790715213577,1.1344567049048861,0.9655270061034027,0.9655270061034027,0.7518547618980741,-0.3628519054147641,1.0923878797824702,-0.17887471357436416,-0.17887471357436416,0.44780670716336934,0.35983999646262926,1.671873243824585
3,216
Heart morphogenesis
7
30
2.349072
0.01882
O75844,P46109,P62942,Q53EL6,Q8NC56,Q12948,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
62,69,10,13,154,232,333
893,62,1703,1481,1761,2771,2414,383,1537,2709,1180,69,1325,10,1188,1553,2264,232,1447,1556,924,2214,865,13,2929,2930,154,333,1081,1644
0.5352790715213577,1.8338555224412796,-0.04237989884272554,0.13769972233839525,-0.0877392581795479,-1.0259824528918617,-0.6432616792979482,1.007923945841884,0.09288087174021684,-0.9293131233315839,0.35983999646262926,1.7935028231987427,0.2713697941390661,3.003616357853454,0.35983999646262926,0.09288087174021684,-0.5023739774096585,1.2600213316709783,0.18238666517970953,0.09288087174021684,0.5352790715213577,-0.45571699704574653,0.5788326555578377,2.889968945701032,-1.2706853562868108,-1.2706853562868108,1.4672078084816735,1.0923878797824702,0.44780670716336934,0.04792884656143651
3,216
Neuron projection organization
16
24
2.348566
0.018846
Q9UQB8,Q14203,O00401,Q9UJU6,Q05086,Q9NUL3,O60678,Q14651,P60953,Q96QK1,P78559,P43034,Q13614,P23528,Q00535,P61160
Processes and pathways
GO Biological process
msigdb_gobp
374,1191,524,410,753,482,185,191,1325,938,289,974,1129,1236,860,536
524,185,1236,974,1833,1325,536,289,860,753,1397,1129,1191,1561,1563,191,1567,1781,1949,938,2015,482,410,374
0.837665032712619,1.3432048961451049,0.31566841450154726,0.4916041220297551,-0.1332370713235067,0.2713697941390661,0.837665032712619,1.1344567049048861,0.5788326555578377,0.6655800443025545,0.22694294684786878,0.40388571004367557,0.35983999646262926,0.09288087174021684,0.09288087174021684,1.3432048961451049,0.09288087174021684,-0.0877392581795479,-0.22465358348725983,0.5352790715213577,-0.2705751034304403,0.9230188420539016,1.007923945841884,1.0502105964224744
3,216
Cortical actin cytoskeleton
13
31
2.335815
0.019501
P46939,Q9UJU6,O00401,Q9Y5X1,Q9NS86,P35579,P46940,Q7L5Y9,P61160,P31146,Q14651,P17655,P60981
Localization
GO Cellular component
msigdb_gocc
457,410,524,442,279,501,286,426,536,413,191,384,389
524,2245,1700,1164,3043,2353,634,384,2526,413,1041,501,457,286,389,536,1188,861,1880,1929,1990,1561,2431,191,1567,1781,426,2019,279,410,442
0.837665032712619,-0.5023739774096585,-0.04237989884272554,0.35983999646262926,-1.5199243531109388,-0.5961446978316173,0.7518547618980741,1.007923945841884,-0.7379672099364472,0.9655270061034027,0.44780670716336934,0.880398505056007,0.9230188420539016,1.1344567049048861,1.007923945841884,0.837665032712619,0.35983999646262926,0.5788326555578377,-0.17887471357436416,-0.22465358348725983,-0.2705751034304403,0.09288087174021684,-0.6432616792979482,1.3432048961451049,0.09288087174021684,-0.0877392581795479,0.9655270061034027,-0.2705751034304403,1.1764179680733708,1.007923945841884,0.9655270061034027
3,216
Renal hypoplasia aplasia
27
82
2.333474
0.019623
P62854,P42766,Q00534,Q9UHX1,Q15392,Q2VPK5,Q6UVJ0,O43709,P62899,P62847,Q9BZH6,P21359,O00443,O43175,Q9NVI1,P60866,P62081,Q15477,P30153,P41227,P35250,P62857,P62244,Q13045,O60828,Q06124,P38398
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
127,4,251,12,652,14,548,282,48,53,475,68,682,684,615,464,75,594,453,579,455,104,585,233,338,353,115
2076,682,1868,684,282,1602,1869,338,2306,1308,1763,1874,2664,1821,68,1315,453,1241,455,1178,115,2710,2778,579,2259,4,2260,704,2808,1667,2781,1926,464,1325,1980,1391,75,585,1496,53,127,104,48,1441,2316,1723,251,353,2156,233,652,2850,594,1930,14,1510,2930,1788,548,2543,2328,2107,2000,2001,2486,1575,3102,2443,999,2551,3011,475,2125,615,1644,3077,12,2759,1420,2134,2068,2650
-0.3628519054147641,0.7087759672510602,-0.17887471357436416,0.7087759672510602,1.1344567049048861,0.04792884656143651,-0.17887471357436416,1.0502105964224744,-0.5491826755969934,0.2713697941390661,-0.0877392581795479,-0.17887471357436416,-0.8812303292626974,-0.1332370713235067,1.7935028231987427,0.2713697941390661,0.9230188420539016,0.31566841450154726,0.9230188420539016,0.35983999646262926,1.5903032740149434,-0.9293131233315839,-1.0259824528918617,0.7948174485841241,-0.5023739774096585,3.707979800175326,-0.5023739774096585,0.7087759672510602,-1.0745728164819957,0.0028423592723265142,-1.0259824528918617,-0.22465358348725983,0.9230188420539016,0.2713697941390661,-0.2705751034304403,0.22694294684786878,1.753055360618528,0.7948174485841241,0.13769972233839525,1.9543521336080658,1.5493709586917743,1.631137115186846,2.0342222402293983,0.18238666517970953,-0.5491826755969934,-0.04237989884272554,1.2182725531206917,1.0502105964224744,-0.40921015652470366,1.2600213316709783,0.7518547618980741,-1.1233362600271486,0.7948174485841241,-0.22465358348725983,2.6605610794808094,0.13769972233839525,-1.2706853562868108,-0.0877392581795479,0.837665032712619,-0.7379672099364472,-0.5491826755969934,-0.3628519054147641,-0.2705751034304403,-0.2705751034304403,-0.6905352848819015,0.09288087174021684,-1.671761793740974,-0.6432616792979482,0.4916041220297551,-0.7379672099364472,-1.4196669272842548,0.9230188420539016,-0.3628519054147641,0.7948174485841241,0.04792884656143651,-1.5703409161105824,2.9279284709975264,-0.977563199292741,0.22694294684786878,-0.3628519054147641,-0.31664072016034606,-0.8333129569784509
3,216
Protein kinase domain [IPR000719]
31
71
2.32704
0.019963
O14757,Q00534,Q02750,P11802,P24941,Q99986,Q9BUB5,P06493,Q9NYV4,P07947,P28482,O14965,Q96KB5,Q9UHY1,Q15208,O95747,P19784,Q8TD19,Q9H2G2,P12931,O75116,Q96SB4,O95819,P78362,Q86UE8,Q13464,Q00535,Q96GX5,P25098,O14976,Q13546
Sequence
InterPro Domain
interpro_domain
246,251,752,633,385,298,300,899,437,901,796,787,178,335,469,67,186,876,1006,451,572,368,961,213,763,757,860,120,852,735,254
246,2462,787,735,1298,1478,572,3113,67,961,2034,2353,899,901,1536,1102,633,451,1485,1918,186,2036,385,852,1824,796,1875,2668,1113,2363,1833,1047,1979,1387,213,251,860,979,752,1553,2925,1555,1726,1883,1447,757,2955,254,1558,1674,469,2589,1568,1993,1131,1931,2220,763,876,120,178,1412,368,1280,2393,298,300,1006,437,1749,335
1.2182725531206917,-0.6905352848819015,0.6222659574604167,0.6655800443025545,0.2713697941390661,0.13769972233839525,0.7948174485841241,-1.773983015941078,1.7935028231987427,0.4916041220297551,-0.31664072016034606,-0.5961446978316173,0.5352790715213577,0.5352790715213577,0.09288087174021684,0.40388571004367557,0.7518547618980741,0.9230188420539016,0.13769972233839525,-0.22465358348725983,1.3432048961451049,-0.31664072016034606,1.007923945841884,0.5788326555578377,-0.1332370713235067,0.6222659574604167,-0.17887471357436416,-0.8812303292626974,0.40388571004367557,-0.5961446978316173,-0.1332370713235067,0.44780670716336934,-0.2705751034304403,0.22694294684786878,1.301665163375922,1.2182725531206917,0.5788326555578377,0.4916041220297551,0.6655800443025545,0.09288087174021684,-1.2706853562868108,0.09288087174021684,-0.04237989884272554,-0.17887471357436416,0.18238666517970953,0.6655800443025545,-1.3201616086849464,1.2182725531206917,0.09288087174021684,0.0028423592723265142,0.9230188420539016,-0.7855591810728211,0.09288087174021684,-0.2705751034304403,0.40388571004367557,-0.22465358348725983,-0.45571699704574653,0.6655800443025545,0.5788326555578377,1.5903032740149434,1.3846413663706636,0.22694294684786878,1.0502105964224744,0.31566841450154726,-0.5961446978316173,1.1344567049048861,1.1344567049048861,0.4916041220297551,0.9655270061034027,-0.04237989884272554,1.0923878797824702
3,216
G2 m checkpoints
46
83
2.323728
0.02014
P14635,O14757,P49736,P35249,Q99460,O00232,P25788,Q9UBD5,Q9UNM6,P24941,O43929,P28072,P35998,P06493,P49721,O00231,P61289,P40938,P25205,P25786,P51665,Q99436,P43686,Q9NWV8,P28066,P28074,P40937,P49720,Q9UL46,O00233,P55036,P35244,P25787,P27694,P25789,Q15008,P33991,Q9NXR7,O75832,P35250,Q13200,P62333,Q92530,P62195,Q06323,P38398
Processes and pathways
Reactome Pathways
msigdb_reactome
740,246,126,745,1074,376,637,1085,566,385,144,638,639,899,39,1017,915,1045,793,794,1048,723,1046,202,1037,1038,702,189,90,204,212,83,82,700,208,984,577,373,956,455,981,586,513,584,354,115
1017,376,204,1296,246,2517,1161,1654,144,2835,956,1759,2869,1761,2771,899,740,2525,1233,1175,385,793,794,82,637,208,2528,700,1037,1825,638,1038,1661,577,1241,1488,83,745,455,639,115,702,1045,1046,1249,189,39,126,2736,1048,2577,212,1122,1495,915,2672,1186,584,2713,586,2369,2629,1501,354,2430,981,1450,2269,2373,984,513,1138,2881,723,1074,2393,2062,202,373,1085,90,566,2133
0.44780670716336934,1.007923945841884,1.301665163375922,0.2713697941390661,1.2182725531206917,-0.7379672099364472,0.35983999646262926,0.0028423592723265142,1.4672078084816735,-1.1233362600271486,0.4916041220297551,-0.0877392581795479,-1.1722747921416414,-0.0877392581795479,-1.0259824528918617,0.5352790715213577,0.6655800443025545,-0.7379672099364472,0.31566841450154726,0.35983999646262926,1.007923945841884,0.6222659574604167,0.6222659574604167,1.7125124116396768,0.7518547618980741,1.301665163375922,-0.7379672099364472,0.7087759672510602,0.44780670716336934,-0.1332370713235067,0.7518547618980741,0.44780670716336934,0.0028423592723265142,0.7948174485841241,0.31566841450154726,0.13769972233839525,1.7125124116396768,0.6655800443025545,0.9230188420539016,0.7518547618980741,1.5903032740149434,0.7087759672510602,0.44780670716336934,0.44780670716336934,0.31566841450154726,1.3432048961451049,2.1533494389689003,1.5493709586917743,-0.977563199292741,0.44780670716336934,-0.7855591810728211,1.301665163375922,0.40388571004367557,0.13769972233839525,0.5352790715213577,-0.8812303292626974,0.35983999646262926,0.7948174485841241,-0.9293131233315839,0.7948174485841241,-0.5961446978316173,-0.8333129569784509,0.13769972233839525,1.0502105964224744,-0.6432616792979482,0.4916041220297551,0.18238666517970953,-0.5023739774096585,-0.5961446978316173,0.4916041220297551,0.880398505056007,0.40388571004367557,-1.1722747921416414,0.7087759672510602,0.44780670716336934,-0.5961446978316173,-0.31664072016034606,1.3432048961451049,1.0502105964224744,0.44780670716336934,1.7125124116396768,0.837665032712619,-0.3628519054147641
3,216
Cysteine protease
20
49
2.322429
0.02021
P54578,Q9NVG8,P17655,Q9Y4P1,Q6GQQ9,Q99497,P55210,Q14674,Q92820,Q9Y5K5,Q13867,P42575,P49915,P55212,Q06210,Q9UPT9,Q66K14,Q96FW1,Q4KMP7,Q96RU2
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
249,141,384,567,293,164,535,423,609,336,214,85,210,93,588,111,509,107,657,132
2654,896,960,1303,1098,1306,1101,384,1033,2952,1431,2898,703,85,854,210,913,249,535,93,978,1500,1052,588,1987,214,423,1400,657,2375,509,293,3126,1514,1946,609,1742,107,1353,132,164,1521,675,141,3090,111,948,567,336
-0.8812303292626974,0.5352790715213577,0.4916041220297551,0.2713697941390661,0.40388571004367557,0.2713697941390661,0.40388571004367557,1.007923945841884,0.44780670716336934,-1.3201616086849464,0.18238666517970953,-1.2213904611668245,0.7087759672510602,1.7125124116396768,0.5788326555578377,1.301665163375922,0.5352790715213577,1.2182725531206917,0.837665032712619,1.671873243824585,0.4916041220297551,0.13769972233839525,0.44780670716336934,0.7948174485841241,-0.2705751034304403,1.301665163375922,0.9655270061034027,0.22694294684786878,0.7518547618980741,-0.5961446978316173,0.880398505056007,1.1344567049048861,-1.8254002143947679,0.13769972233839525,-0.22465358348725983,0.7948174485841241,-0.04237989884272554,1.631137115186846,0.2713697941390661,1.5493709586917743,1.4259753991464208,0.13769972233839525,0.7518547618980741,1.5083393975097876,-1.620952575855485,1.631137115186846,0.5352790715213577,0.837665032712619,1.0923878797824702
3,216
Hsp90 protein binding
12
18
2.321676
0.02025
O95801,O95433,Q9UHD1,Q9Y4R8,Q16543,Q15185,P23396,Q00535,P37198,Q9H3U1,Q08752,Q9UNE7
Functions
GO Molecular function
msigdb_gomf
575,92,409,834,1060,923,1034,860,84,1078,919,565
1303,92,575,1034,1712,84,2091,1118,1925,860,919,1451,923,1060,1078,409,565,834
0.2713697941390661,1.671873243824585,0.7948174485841241,0.44780670716336934,-0.04237989884272554,1.7125124116396768,-0.3628519054147641,0.40388571004367557,-0.22465358348725983,0.5788326555578377,0.5352790715213577,0.18238666517970953,0.5352790715213577,0.44780670716336934,0.44780670716336934,1.007923945841884,0.837665032712619,0.6222659574604167
3,216
Nucleotide sugar biosynthetic process
6
8
2.318843
0.020404
Q06210,Q9NR45,Q16222,Q96EK6,O60547,O95394
Processes and pathways
GO Biological process
msigdb_gobp
588,614,315,274,73,170
73,1163,170,797,588,315,274,614
1.753055360618528,0.35983999646262926,1.3846413663706636,0.6222659574604167,0.7948174485841241,1.0923878797824702,1.1764179680733708,0.7948174485841241
3,216
Serine protease
7
26
2.311053
0.02083
Q15366,Q86TI2,P42785,Q15365,P48147,Q9HB40,Q9H3G5
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
94,196,6,236,345,156,27
1752,377,1818,1030,971,2777,6,345,2972,2152,2368,2159,236,94,196,3087,1406,996,1139,1792,2010,27,156,1957,1086,1912
-0.0877392581795479,1.007923945841884,-0.1332370713235067,0.44780670716336934,0.4916041220297551,-1.0259824528918617,3.598463949293977,1.0502105964224744,-1.369821392742899,-0.40921015652470366,-0.5961446978316173,-0.40921015652470366,1.2600213316709783,1.671873243824585,1.3432048961451049,-1.620952575855485,0.22694294684786878,0.4916041220297551,0.40388571004367557,-0.0877392581795479,-0.2705751034304403,2.3501300710324777,1.4672078084816735,-0.22465358348725983,0.44780670716336934,-0.17887471357436416
3,216
Cell cycle g1 s phase transition
23
64
2.307361
0.021035
P15170,Q00534,P23634,O95905,P62753,Q6UVJ0,P06730,P27695,P24941,Q9UKG1,Q96DY7,Q13309,P31350,Q13616,Q7L2J0,Q9UL46,P42575,O00743,P42771,P06400,Q06323,Q04637,Q7Z7L1
Processes and pathways
GO Biological process
msigdb_gobp
496,251,136,135,270,548,630,147,385,303,45,290,414,540,318,90,85,444,580,341,354,505,398
1368,2516,444,3042,135,1028,2771,2841,341,630,633,496,2525,2146,136,1238,385,147,414,1041,85,580,1830,915,270,1722,251,860,979,505,354,862,980,1260,290,540,1262,1559,1560,1329,1988,2215,1887,2541,548,1789,318,398,1135,1790,3186,1460,2546,933,45,1743,3033,1899,1808,303,90,1750,2612,1422
0.22694294684786878,-0.7379672099364472,0.9230188420539016,-1.5199243531109388,1.5083393975097876,0.44780670716336934,-1.0259824528918617,-1.1233362600271486,1.0502105964224744,0.7518547618980741,0.7518547618980741,0.880398505056007,-0.7379672099364472,-0.40921015652470366,1.5083393975097876,0.31566841450154726,1.007923945841884,1.4672078084816735,0.9655270061034027,0.44780670716336934,1.7125124116396768,0.7948174485841241,-0.1332370713235067,0.5352790715213577,1.1764179680733708,-0.04237989884272554,1.2182725531206917,0.5788326555578377,0.4916041220297551,0.880398505056007,1.0502105964224744,0.5788326555578377,0.4916041220297551,0.31566841450154726,1.1344567049048861,0.837665032712619,0.31566841450154726,0.09288087174021684,0.09288087174021684,0.2713697941390661,-0.2705751034304403,-0.45571699704574653,-0.17887471357436416,-0.7379672099364472,0.837665032712619,-0.0877392581795479,1.0923878797824702,1.007923945841884,0.40388571004367557,-0.0877392581795479,-2.405349762622622,0.18238666517970953,-0.7379672099364472,0.5352790715213577,2.07402103934834,-0.04237989884272554,-1.4697004768647024,-0.17887471357436416,-0.0877392581795479,1.1344567049048861,1.7125124116396768,-0.04237989884272554,-0.7855591810728211,0.22694294684786878
3,216
Pyrimidine nucleobase metabolic process
11
14
2.301304
0.021374
Q9NRF8,P28482,P30085,O76075,Q14195,P17812,P11172,Q16555,Q02252,O14531,Q9BPU6
Processes and pathways
GO Biological process
msigdb_gobp
675,796,907,227,814,1033,1170,655,1051,733,768
733,227,1609,1170,1033,1431,796,907,1180,1051,814,655,768,675
0.6655800443025545,1.2600213316709783,0.04792884656143651,0.35983999646262926,0.44780670716336934,0.18238666517970953,0.6222659574604167,0.5352790715213577,0.35983999646262926,0.44780670716336934,0.6222659574604167,0.7518547618980741,0.6655800443025545,0.7518547618980741
3,216
Nucleobase metabolic process
19
25
2.298375
0.02154
P22102,Q9NRF8,Q14195,P00492,P60891,P28482,P30085,P17812,P11172,Q06203,Q02252,P49915,Q9BPU6,P34896,P22234,P07741,O76075,Q16555,O14531
Processes and pathways
GO Biological process
msigdb_gobp
742,675,814,628,646,796,907,1033,1170,1052,1051,210,768,454,1107,1099,227,655,733
733,2348,227,628,1609,1099,1170,1033,742,1107,1431,796,907,454,2806,1180,210,646,1051,1052,814,655,768,675,1475
0.6655800443025545,-0.5961446978316173,1.2600213316709783,0.7518547618980741,0.04792884656143651,0.40388571004367557,0.35983999646262926,0.44780670716336934,0.6655800443025545,0.40388571004367557,0.18238666517970953,0.6222659574604167,0.5352790715213577,0.9230188420539016,-1.0745728164819957,0.35983999646262926,1.301665163375922,0.7518547618980741,0.44780670716336934,0.44780670716336934,0.6222659574604167,0.7518547618980741,0.6655800443025545,0.7518547618980741,0.18238666517970953
3,216
Regulation of cell matrix adhesion
17
30
2.297163
0.021609
P42771,P46939,P21359,Q00534,P51452,Q9P258,O75122,Q9H2G2,Q9P1Y5,Q9UPN3,P14923,P49593,Q13464,O75116,P12931,O95819,O14786
Processes and pathways
GO Biological process
msigdb_gobp
580,457,68,251,642,280,686,1006,617,484,847,347,757,572,451,961,893
893,2462,572,686,961,451,847,1820,1106,68,580,457,347,1833,642,1185,1836,1188,251,1553,757,1065,1516,1006,2064,617,280,2300,484,2862
0.5352790715213577,-0.6905352848819015,0.7948174485841241,0.7087759672510602,0.4916041220297551,0.9230188420539016,0.5788326555578377,-0.1332370713235067,0.40388571004367557,1.7935028231987427,0.7948174485841241,0.9230188420539016,1.0502105964224744,-0.1332370713235067,0.7518547618980741,0.35983999646262926,-0.1332370713235067,0.35983999646262926,1.2182725531206917,0.09288087174021684,0.6655800443025545,0.44780670716336934,0.13769972233839525,0.4916041220297551,-0.31664072016034606,0.7948174485841241,1.1764179680733708,-0.5023739774096585,0.9230188420539016,-1.1233362600271486
3,216
Secondary metabolic process
7
12
2.291684
0.021924
Q9UKG1,O14908,P40616,Q9HBK9,P30046,Q9Y4G8,O43488
Processes and pathways
GO Biological process
msigdb_gobp
303,840,285,278,531,521,445
840,445,1301,846,1708,531,285,1136,278,303,521,1529
0.5788326555578377,0.9230188420539016,0.2713697941390661,0.5788326555578377,-0.04237989884272554,0.837665032712619,1.1344567049048861,0.40388571004367557,1.1764179680733708,1.1344567049048861,0.880398505056007,0.13769972233839525
3,216
Golgi organization
29
56
2.291279
0.021947
Q15363,Q02750,Q9UL15,Q08379,Q9BTU6,O15155,O15027,Q9H8Y8,Q9UID3,O60763,Q99986,Q13190,Q9UJC3,P06493,Q96JB2,P40616,P28482,O43264,Q92614,Q7Z6Z7,Q9H0V9,O75122,Q9P1Y5,Q14789,Q8NF91,Q9H4A6,Q7Z460,O14976,Q92538
Processes and pathways
GO Biological process
msigdb_gobp
924,752,142,754,941,378,21,1079,564,625,298,1056,167,899,37,285,796,1021,323,600,478,686,617,508,259,121,1065,735,401
1477,735,21,378,1653,1021,625,686,2867,899,796,2668,285,2670,1714,1716,1491,1325,2366,1439,2629,752,754,1398,1056,508,2678,924,1265,1734,1065,600,1575,259,1137,1680,401,323,2790,37,298,941,1852,478,121,1079,617,2400,564,167,142,1291,2067,1911,2243,1650
0.13769972233839525,0.6655800443025545,2.467167035925966,1.007923945841884,0.0028423592723265142,0.44780670716336934,0.7518547618980741,0.7087759672510602,-1.1722747921416414,0.5352790715213577,0.6222659574604167,-0.8812303292626974,1.1344567049048861,-0.8812303292626974,-0.04237989884272554,-0.04237989884272554,0.13769972233839525,0.2713697941390661,-0.5961446978316173,0.18238666517970953,-0.8333129569784509,0.6655800443025545,0.6655800443025545,0.22694294684786878,0.44780670716336934,0.880398505056007,-0.8812303292626974,0.5352790715213577,0.31566841450154726,-0.04237989884272554,0.44780670716336934,0.7948174485841241,0.09288087174021684,1.2182725531206917,0.40388571004367557,0.0028423592723265142,1.007923945841884,1.0923878797824702,-1.0259824528918617,2.1928803390588034,1.1344567049048861,0.5352790715213577,-0.1332370713235067,0.9230188420539016,1.5903032740149434,0.44780670716336934,0.7948174485841241,-0.5961446978316173,0.837665032712619,1.4259753991464208,1.5083393975097876,0.31566841450154726,-0.31664072016034606,-0.17887471357436416,-0.45571699704574653,0.04792884656143651
3,216
Thiol protease
15
37
2.288282
0.022121
P54578,Q9Y5K5,P55212,Q96BN8,Q9UPT9,Q9H8M7,Q96FW1,P55210,P17655,Q13867,P42575,Q14674,Q96RU2,Q9Y4P1,Q6GQQ9
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
249,336,93,365,111,479,107,535,384,214,85,423,132,567,293
1423,2654,960,1303,1098,1306,384,2898,703,85,854,913,249,535,93,1500,214,423,1400,293,601,3126,1946,1276,1742,365,107,1353,132,2937,479,2020,3090,111,1594,567,336
0.18238666517970953,-0.8812303292626974,0.4916041220297551,0.2713697941390661,0.40388571004367557,0.2713697941390661,1.007923945841884,-1.2213904611668245,0.7087759672510602,1.7125124116396768,0.5788326555578377,0.5352790715213577,1.2182725531206917,0.837665032712619,1.671873243824585,0.13769972233839525,1.301665163375922,0.9655270061034027,0.22694294684786878,1.1344567049048861,0.7948174485841241,-1.8254002143947679,-0.22465358348725983,0.31566841450154726,-0.04237989884272554,1.0502105964224744,1.631137115186846,0.2713697941390661,1.5493709586917743,-1.2706853562868108,0.9230188420539016,-0.2705751034304403,-1.620952575855485,1.631137115186846,0.09288087174021684,0.837665032712619,1.0923878797824702
3,216
Lysosome
32
48
5.364977
0
P07858,O75503,Q9UMR5,Q14108,P11717,P11117,Q99523,P06865,O14773,Q93050,P06280,P20645,P15586,P07602,P38571,Q15904,P16278,P04066,P50897,Q8NCC3,P17900,P07686,P13473,P53634,Q13510,P11279,P61916,P10253,P54802,P10619,P08236,O15118
Processes and pathways
KEGG Pathways
msigdb_kegg
0,2,7,11,12,17,18,23,24,157,26,155,27,29,30,32,33,35,36,40,42,44,45,51,52,56,61,64,69,79,86,107
2462,1187,24,107,449,1988,2,159,35,26,23,29,44,0,86,2002,2102,64,79,17,56,12,45,488,27,33,42,155,30,36,51,69,2026,61,1131,2760,52,11,32,40,157,18,2606,2732,2608,7,1270,1093
-0.40402796001592817,0.12650352299120168,4.277231780522513,1.6664604613196916,0.6047441298103642,-0.19312440504741912,5.67744432884677,1.2579598722922671,3.87251063452273,4.26176622208897,4.292640613113165,4.103903861507434,3.4815095543021095,5.753445296545432,2.041713109359675,-0.19312440504741912,-0.23458778988890483,2.8413768979798424,2.168593039711846,4.560717760021575,3.0310607725274514,4.7578979042593295,3.4628646813851485,0.56959932165332,4.215025312761425,3.9231664931029746,3.500074419325368,1.3185597442809507,4.0877879744567425,3.838402606892822,3.252302731114541,2.6656619725373503,-0.19312440504741912,2.9055148859879574,0.16502117881402548,-0.5794889536111877,3.212899993952183,4.932922918773284,3.939918756974266,3.5735462991655385,1.3185597442809507,4.517217269678972,-0.447313538439276,-0.5350376937165657,-0.447313538439276,5.200738426526624,0.12650352299120168,0.2032352560941832
3,282
Vacuolar lumen
28
64
4.75267
0.000002
P07858,Q8NHP8,Q9UMR5,Q14108,O00584,P11117,Q9BTY2,P06865,O14773,P06280,P15586,P07602,P38571,P16278,P04066,P50897,P17900,P07686,P13473,P53634,Q92820,Q13510,Q8IV08,P61916,P10253,P54802,P10619,Q13217
Localization
GO Cellular component
msigdb_gocc
0,6,7,11,14,17,22,23,24,26,27,29,30,33,35,36,42,44,45,51,53,52,60,61,64,69,79,85
191,14,24,449,2683,159,35,26,23,1682,2000,29,44,0,1780,86,64,79,17,2618,261,45,488,27,33,42,2108,1295,2399,428,30,1913,36,1598,2625,51,236,69,2329,1603,61,2992,2497,85,52,11,599,60,219,1246,6,53,2718,851,2065,336,22,1960,199,719,2284,2606,7,1758
1.1029366858806233,4.6604814214743495,4.277231780522513,0.6047441298103642,-0.5350376937165657,1.2579598722922671,3.87251063452273,4.26176622208897,4.292640613113165,-0.0707984520875663,-0.19312440504741912,4.103903861507434,3.4815095543021095,5.753445296545432,-0.111235007560292,2.041713109359675,2.8413768979798424,2.168593039711846,4.560717760021575,-0.49098136096966877,0.9099005907750538,3.4628646813851485,0.56959932165332,4.215025312761425,3.9231664931029746,3.500074419325368,-0.23458778988890483,0.08767781508561892,-0.3611185057888075,0.6396323861878013,4.0877879744567425,-0.15200858779369664,3.838402606892822,-0.030693823997864408,-0.49098136096966877,3.252302731114541,0.9751275234742037,2.6656619725373503,-0.3185791975969145,-0.030693823997864408,2.9055148859879574,-0.8548695870458013,-0.40402796001592817,2.06737403906276,3.212899993952183,4.932922918773284,0.46259025776509327,2.9687348703738783,1.0394655325228437,0.12650352299120168,5.237597947054696,3.212899993952183,-0.5350376937165657,0.3160993567708542,-0.19312440504741912,0.7766874995730636,4.353716272878836,-0.15200858779369664,1.1029366858806233,0.3899020970665093,-0.2764041947467008,-0.447313538439276,5.200738426526624,-0.0707984520875663
3,282
Lysosomal lumen
24
34
4.543797
0.000006
P07858,Q8NHP8,Q9UMR5,Q14108,O00584,P11117,P06865,O14773,P06280,P15586,P07602,P38571,P16278,P04066,P50897,P17900,P07686,P13473,Q13510,Q8IV08,P61916,P10253,P54802,P10619
Localization
GO Cellular component
msigdb_gocc
0,6,7,11,14,17,23,24,26,27,29,30,33,35,36,42,44,45,52,60,61,64,69,79
14,24,449,159,35,26,23,29,44,0,1780,86,64,79,17,2618,45,488,27,33,42,428,30,36,69,61,52,11,60,1246,6,1960,2606,7
4.6604814214743495,4.277231780522513,0.6047441298103642,1.2579598722922671,3.87251063452273,4.26176622208897,4.292640613113165,4.103903861507434,3.4815095543021095,5.753445296545432,-0.111235007560292,2.041713109359675,2.8413768979798424,2.168593039711846,4.560717760021575,-0.49098136096966877,3.4628646813851485,0.56959932165332,4.215025312761425,3.9231664931029746,3.500074419325368,0.6396323861878013,4.0877879744567425,3.838402606892822,2.6656619725373503,2.9055148859879574,3.212899993952183,4.932922918773284,2.9687348703738783,0.12650352299120168,5.237597947054696,-0.15200858779369664,-0.447313538439276,5.200738426526624
3,282
Predicted secreted proteins
19
50
4.458864
0.000008
P07858,P05067,Q9HB40,Q8WUJ1,O00584,P02786,Q9BTY2,Q08380,Q13740,Q9UMX5,P81605,O94813,P61916,O14786,O60888,Q6UX07,P78310,P80303,Q02818
Functions
Protein Atlas Protein class
protein_atlas_protein_class
0,4,5,13,14,16,22,25,168,38,39,49,61,73,76,218,94,239,121
14,73,76,1676,49,398,16,3134,4,1470,1682,0,1574,1033,1472,1474,2960,1293,1482,690,1041,406,61,94,239,39,692,121,269,25,1923,598,168,3038,218,2430,2714,13,438,921,2651,1257,22,3162,2659,5,1353,2286,38,1359
4.6604814214743495,2.5522102634243087,2.4121580026151745,-0.0707984520875663,3.3107473082227377,0.6742675203720525,4.603767689214678,-1.2985357058248468,5.3462035778791,0.009083862508249637,-0.0707984520875663,5.753445296545432,-0.030693823997864408,0.2032352560941832,0.009083862508249637,0.009083862508249637,-0.8079049323129223,0.08767781508561892,0.009083862508249637,0.3899020970665093,0.2032352560941832,0.6742675203720525,2.9055148859879574,1.8846389427321497,0.9751275234742037,3.6991826624021256,0.3899020970665093,1.5533696386158045,0.9099005907750538,4.277231780522513,-0.15200858779369664,0.46259025776509327,1.2273627870166264,-0.9501402031747567,1.0394655325228437,-0.3611185057888075,-0.5350376937165657,4.7302981957844255,0.6396323861878013,0.27877010153248377,-0.49098136096966877,0.12650352299120168,4.353716272878836,-1.4555046969677865,-0.49098136096966877,5.3462035778791,0.08767781508561892,-0.2764041947467008,3.7519220076034654,0.08767781508561892
3,282
Azurophil granule
29
67
4.225593
0.000024
Q92542,P11216,O00584,Q9BTY2,P06865,P06280,P15586,P07602,P42785,P16278,P04066,P17900,P07686,P13473,P53634,Q92820,P11279,P61916,P10253,Q9H0E2,O00560,P10619,Q13217,P08236,Q8N1F8,P51809,O15260,P53990,Q6IAA8
Localization
GO Cellular component
msigdb_gocc
132,261,14,22,23,26,27,29,31,33,35,42,44,45,51,53,56,61,64,199,191,79,85,86,219,215,99,236,253
1096,191,14,99,259,449,881,2303,2683,35,26,23,1682,2000,29,44,86,64,79,261,56,45,488,27,33,42,2108,1295,2399,1590,31,1913,1598,1805,404,215,2625,51,236,2329,1603,61,2992,2497,2900,85,599,253,219,1246,1068,132,53,2718,851,2065,3043,336,22,199,785,719,338,2284,2606,1750,1758
0.16502117881402548,1.1029366858806233,4.6604814214743495,1.804031534347235,0.9099005907750538,0.6047441298103642,0.27877010153248377,-0.3185791975969145,-0.5350376937165657,3.87251063452273,4.26176622208897,4.292640613113165,-0.0707984520875663,-0.19312440504741912,4.103903861507434,3.4815095543021095,2.041713109359675,2.8413768979798424,2.168593039711846,0.9099005907750538,3.0310607725274514,3.4628646813851485,0.56959932165332,4.215025312761425,3.9231664931029746,3.500074419325368,-0.23458778988890483,0.08767781508561892,-0.3611185057888075,-0.030693823997864408,3.989783179076656,-0.15200858779369664,-0.030693823997864408,-0.111235007560292,0.6742675203720525,1.0394655325228437,-0.49098136096966877,3.252302731114541,0.9751275234742037,-0.3185791975969145,-0.030693823997864408,2.9055148859879574,-0.8548695870458013,-0.40402796001592817,-0.7152788300849903,2.06737403906276,0.46259025776509327,0.9426265837130483,1.0394655325228437,0.12650352299120168,0.2032352560941832,1.4667004291339405,3.212899993952183,-0.5350376937165657,0.3160993567708542,-0.19312440504741912,-0.9501402031747567,0.7766874995730636,4.353716272878836,1.1029366858806233,0.35314201253011507,0.3899020970665093,0.7766874995730636,-0.2764041947467008,-0.447313538439276,-0.0707984520875663,-0.0707984520875663
3,282
Azurophil granule lumen
18
43
4.141138
0.000035
P16278,Q9H0E2,P04066,Q8N1F8,O00560,P17900,P07686,O00584,P10619,P53634,Q92820,Q13217,Q9BTY2,P08236,P53990,P06280,P15586,P61916
Localization
GO Cellular component
msigdb_gocc
33,199,35,219,191,42,44,14,79,51,53,85,22,86,236,26,27,61
191,14,449,2683,35,26,1682,2000,44,86,79,261,488,27,33,42,2108,1295,2399,1913,1598,2625,51,236,2329,1603,61,2992,2497,85,599,219,1246,53,2718,851,2065,336,22,199,719,2284,1758
1.1029366858806233,4.6604814214743495,0.6047441298103642,-0.5350376937165657,3.87251063452273,4.26176622208897,-0.0707984520875663,-0.19312440504741912,3.4815095543021095,2.041713109359675,2.168593039711846,0.9099005907750538,0.56959932165332,4.215025312761425,3.9231664931029746,3.500074419325368,-0.23458778988890483,0.08767781508561892,-0.3611185057888075,-0.15200858779369664,-0.030693823997864408,-0.49098136096966877,3.252302731114541,0.9751275234742037,-0.3185791975969145,-0.030693823997864408,2.9055148859879574,-0.8548695870458013,-0.40402796001592817,2.06737403906276,0.46259025776509327,1.0394655325228437,0.12650352299120168,3.212899993952183,-0.5350376937165657,0.3160993567708542,-0.19312440504741912,0.7766874995730636,4.353716272878836,1.1029366858806233,0.3899020970665093,-0.2764041947467008,-0.0707984520875663
3,282
Receptor
21
42
4.122068
0.000038
Q14108,P11717,P02786,Q99523,Q8WTV0,P20645,P35613,Q99720,P11279,O15173,O43731,Q9UBG0,O14786,P01130,P78310,P30825,O15118,Q9Y624,Q15375,Q14739,O75787
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
11,12,16,18,19,155,160,37,56,182,67,70,73,84,94,119,107,114,116,251,125
798,73,107,182,67,125,84,16,346,806,2557,2745,2310,887,56,12,1033,1474,155,1208,3195,119,160,94,2132,598,11,251,116,302,19,2266,18,580,37,275,2074,70,1452,2733,1455,114
0.3160993567708542,2.5522102634243087,1.6664604613196916,1.134353871041638,2.7102464547228364,1.4957705084798452,2.06737403906276,4.603767689214678,0.7427918101594553,0.3160993567708542,-0.447313538439276,-0.5794889536111877,-0.3185791975969145,0.27877010153248377,3.0310607725274514,4.7578979042593295,0.2032352560941832,0.009083862508249637,1.3185597442809507,0.12650352299120168,-1.7283355176816686,1.5533696386158045,1.2579598722922671,1.8846389427321497,-0.23458778988890483,0.46259025776509327,4.932922918773284,0.9426265837130483,1.581902787928283,0.8437618381301556,4.502615473564737,-0.2764041947467008,4.517217269678972,0.49852598917224417,3.769358541744768,0.9099005907750538,-0.19312440504741912,2.6656619725373503,0.04853948483886928,-0.5350376937165657,0.04853948483886928,1.6102610028367177
3,282
Endocytic vesicle membrane
15
42
4.057498
0.00005
O95782,Q06481,Q14108,P11717,Q9ULC3,P13473,P04439,P02786,P10321,Q8WTV0,P01130,P11279,Q93050,Q5T9L3,P01889
Localization
GO Cellular component
msigdb_gocc
135,10,11,12,143,45,75,16,78,19,84,56,157,95,63
1096,1282,740,135,84,63,16,75,520,78,56,12,45,490,155,814,2407,1039,215,2897,1807,2026,1128,1131,1497,10,1315,2035,907,11,765,1053,834,604,95,19,157,2355,2654,3205,143,1093
0.16502117881402548,0.08767781508561892,0.35314201253011507,1.437447216839773,2.06737403906276,2.862859742674559,4.603767689214678,2.4358057896568965,0.5341944639917007,2.2183679057537216,3.0310607725274514,4.7578979042593295,3.4628646813851485,0.56959932165332,1.3185597442809507,0.3160993567708542,-0.3611185057888075,0.2032352560941832,1.0394655325228437,-0.7152788300849903,-0.111235007560292,-0.19312440504741912,0.16502117881402548,0.16502117881402548,0.009083862508249637,4.95919967585301,0.08767781508561892,-0.19312440504741912,0.27877010153248377,4.932922918773284,0.35314201253011507,0.2032352560941832,0.3160993567708542,0.46259025776509327,1.8846389427321497,4.502615473564737,1.3185597442809507,-0.3185791975969145,-0.49098136096966877,-1.784685260337117,1.408008734553272,0.2032352560941832
3,282