term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial myopathy
10
28
3.233196
0.001224
O75306,P00403,P03886,P00846,P12235,Q9Y606,O75380,Q9Y6M9,O43676,Q9NPL8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,162,3,4,253,269,292,246,145,161
2498,145,2747,974,226,292,1705,1081,162,4,3,253,2434,2380,1325,1259,2078,2407,993,895,822,311,1981,161,1545,1032,269,246
-0.5045745330084603,1.6539488897454098,-0.6811632058277461,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.025548389325393668,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,1.2572514626291789,-0.44656700343867023,-0.41772541135227015,0.18851682862821462,0.2147447157493263,-0.21890038394992256,-0.41772541135227015,0.3949590324162235,0.4703509047116417,0.5199959431965512,1.1041400729155888,-0.16309171563110678,1.6133853485657363,0.08241993256639264,0.3695803896161305,1.2139174422855383,1.3002667781715258
3,401
Polysomal ribosome
12
26
3.211834
0.001319
P62266,P84098,Q02543,P62854,Q07020,P62917,Q02878,P83731,P62424,P83881,P62910,Q9Y3U8
Localization
GO Cellular component
msigdb_gocc
165,171,105,234,149,113,119,217,118,222,191,192
1072,1159,165,118,234,1327,1169,1376,308,191,1052,113,541,678,217,222,171,105,119,149,2392,1058,2122,2949,2980,192
0.3184545058121038,0.2668410830881398,1.5930038530109396,1.8136359864985119,1.32165710213149,0.18851682862821462,0.2668410830881398,0.16216987090011553,1.1041400729155888,1.4692762530118126,0.3440786823573308,1.8333179734584413,0.7613131382611684,0.6178655297596958,1.385368830001817,1.3642073059600701,1.5725549938573544,1.8920056904356866,1.8136359864985119,1.6539488897454098,-0.41772541135227015,0.3440786823573308,-0.2469724530743794,-0.8615367583845711,-0.8919614192603897,1.4692762530118126
3,401
Steroid biosynthesis
10
23
3.198523
0.001381
Q9UHQ9,Q9UBM7,Q9UKR5,Q15392,O75845,Q13131,P04035,Q14739,Q16850,P48449
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
362,39,137,7,316,425,443,106,53,125
316,1308,443,1464,2008,125,465,2693,984,425,1523,106,7,1270,2573,53,780,2267,2769,1184,39,362,137
1.0819296780167726,0.18851682862821462,0.9010133357750852,0.10912089420536077,-0.19093998781040267,1.7740895644817878,0.8779778896871095,-0.6218757596842738,0.3949590324162235,0.9239525336517246,0.08241993256639264,1.8920056904356866,4.133951074558761,0.2147447157493263,-0.5337396628232933,2.487824819755659,0.544638339789795,-0.3318542687573309,-0.6811632058277461,0.2668410830881398,2.8019254667161024,1.014770461288004,1.7143052013527764
3,401
Nucleotide transmembrane transporter activity
10
14
3.146995
0.00165
Q9BSK2,O43808,P12235,P41440,Q9HC21,O00400,Q8TB61,Q99808,P12236,Q9H2D1
Functions
GO Molecular function
msigdb_gomf
32,35,253,70,74,11,140,274,462,484
11,1607,35,537,253,462,70,1057,2404,140,274,32,484,74
3.8544190981954287,0.028667653788611115,2.8360067907741575,0.7613131382611684,1.2572514626291789,0.8779778896871095,2.177822330333986,0.3440786823573308,-0.41772541135227015,1.6942507925226085,1.1921286759414857,2.9540811147426025,0.8548449707097387,2.1404139980394676
3,401
Organophosphate ester transmembrane transporter activity
10
14
3.146995
0.00165
Q9BSK2,O43808,P12235,P41440,Q9HC21,O00400,Q8TB61,Q99808,P12236,Q9H2D1
Functions
GO Molecular function
msigdb_gomf
32,35,253,70,74,11,140,274,462,484
11,1607,35,537,253,462,70,1057,2404,140,274,32,484,74
3.8544190981954287,0.028667653788611115,2.8360067907741575,0.7613131382611684,1.2572514626291789,0.8779778896871095,2.177822330333986,0.3440786823573308,-0.41772541135227015,1.6942507925226085,1.1921286759414857,2.9540811147426025,0.8548449707097387,2.1404139980394676
3,401
Abnormal erythrocyte enzyme level
12
21
3.142762
0.001674
P62847,P08708,P18077,P46777,P61313,P62854,Q07020,P00813,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,331,109,234,149,18,367,402,339,221
18,508,444,2992,221,331,2111,402,367,109,339,843,773,297,234,1327,1376,1052,149,591,1978
3.53430786323273,0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.7139285396999346,-0.16309171563110678
3,401
Abnormal urine ph
12
41
3.125611
0.001774
P03886,P00846,Q4G176,P12235,Q9HC21,P08397,Q96RQ3,O43772,Q9Y399,P48735,P23786,O75880
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,4,132,253,74,232,410,47,350,19,364,28
47,28,1081,4,3,1364,2431,232,1557,253,2781,1369,364,1858,910,2691,1214,19,2384,1124,2113,1518,400,1126,984,2400,1383,2699,132,1684,1822,1346,410,1294,1745,74,2542,2462,1749,350,1755
2.629109857257126,3.020731201810017,0.3184545058121038,4.4328621068997585,4.544166984823674,0.16216987090011553,-0.44656700343867023,1.32165710213149,0.05560201529260138,1.2572514626291789,-0.710964802828651,0.16216987090011553,0.9922045075089839,-0.10773337464269757,0.4453447000259606,-0.6218757596842738,0.2408529853896325,3.53430786323273,-0.41772541135227015,0.2927084466196836,-0.2469724530743794,0.08241993256639264,0.9467966825508827,0.2927084466196836,0.3949590324162235,-0.41772541135227015,0.16216987090011553,-0.6218757596842738,1.7342960667860914,0.001617352823824191,-0.08022423571315228,0.18851682862821462,0.9467966825508827,0.2147447157493263,-0.025548389325393668,2.1404139980394676,-0.5045745330084603,-0.44656700343867023,-0.025548389325393668,1.037245922867657,-0.025548389325393668
3,401
Optic neuropathy
6
21
3.122127
0.001795
O75306,P03886,P00846,Q9Y6M9,O43676,Q9NPL8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,3,4,246,145,161
2498,145,974,226,292,1705,1081,4,3,2434,2380,1046,1325,2407,919,993,822,161,1545,929,246
-0.5045745330084603,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.025548389325393668,0.3184545058121038,4.4328621068997585,4.544166984823674,-0.44656700343867023,-0.41772541135227015,0.3440786823573308,0.18851682862821462,-0.41772541135227015,0.4453447000259606,0.3949590324162235,0.5199959431965512,1.6133853485657363,0.08241993256639264,0.4453447000259606,1.3002667781715258
3,401
Translation
95
220
3.106347
0.001894
P08708,O43324,P62841,P62750,P63173,P67812,Q15629,P46776,P49207,P60059,Q9Y2R9,Q9UI30,Q9P015,Q9BRJ2,P60228,P26640,Q15070,Q9NX20,Q02543,P61313,P62753,Q9P0M9,P62917,Q02878,Q14240,P62424,P09132,P35268,Q14152,Q13144,O60841,Q07020,P36578,Q05639,P18124,Q8TAE8,P18621,P62266,P63220,P84098,O43776,P50914,P27635,P40429,P13798,Q9BYD1,Q9H9J2,P62263,P62910,Q9Y3U8,P61927,Q5ST30,P62241,O15235,P39023,P49406,P62269,P83731,P15880,P83881,P42766,P46779,P47914,P82933,P62854,P62701,P82914,O75616,P46778,P62277,P55010,P82912,P46781,P62847,Q9Y5M8,P62906,P61513,P61247,Q9Y2R5,P26373,P46777,Q9Y399,P82930,P61353,P61254,Q9NYK5,P60866,P32969,P82675,P62280,P18077,P61619,O76094,P26641,Q9Y262
Processes and pathways
Reactome Pathways
msigdb_reactome
508,502,529,540,541,42,52,557,558,561,599,617,613,610,604,603,104,634,105,109,110,112,113,119,120,118,117,621,653,651,642,149,148,649,154,685,164,165,678,171,667,169,174,175,673,177,717,190,191,192,189,709,195,692,205,702,705,217,215,222,221,227,228,235,234,233,249,262,264,265,267,280,279,297,301,308,307,306,328,317,331,350,340,339,367,414,402,422,424,447,444,467,459,476,500
1840,692,936,1072,502,667,642,262,1509,2336,459,2286,1800,2148,3007,1709,1311,1765,2880,508,2149,1042,117,1663,1010,673,1558,1366,215,444,154,164,1044,2005,1317,2290,1617,2108,317,1667,603,476,174,2560,1162,422,621,148,2437,2992,205,2249,175,2605,1955,221,2293,1046,1121,557,331,264,227,279,801,2111,1048,228,558,702,1900,2653,2297,2969,1565,1472,169,944,2153,3042,1166,2654,267,1717,2254,3089,561,604,878,2348,402,1776,1718,306,367,109,339,307,467,189,843,195,773,1569,190,165,705,265,447,118,1624,233,540,110,706,529,297,844,234,1327,2608,1169,1376,308,191,1052,113,541,678,42,2972,1570,2993,424,280,249,340,235,217,222,171,105,119,2258,649,149,2519,2393,651,2446,1268,2448,653,1382,1630,120,2731,742,1680,2353,104,2572,52,1094,2526,709,1682,781,1867,1335,811,960,1135,2736,685,1528,2981,1490,1022,2671,1394,2318,2271,610,761,177,1023,2741,1182,1142,1143,717,1650,2363,1448,1540,2225,1350,2744,1544,634,414,613,112,1401,1501,1068,617,500,1191,1031,328,599,1032,350,2282,1107,2775,192,301
-0.10773337464269757,0.5935714761388575,0.42021400684349175,0.3184545058121038,0.8082816835493837,0.6178655297596958,0.642046718499613,1.2356247347543958,0.08241993256639264,-0.3889924804727667,0.8779778896871095,-0.3603686262084453,-0.08022423571315228,-0.27515574959433703,-0.9531181920204688,-0.025548389325393668,0.18851682862821462,-0.05282908073775324,-0.8009966357602808,0.8082816835493837,-0.27515574959433703,0.3440786823573308,1.8136359864985119,0.001617352823824191,0.3695803896161305,0.6178655297596958,0.05560201529260138,0.16216987090011553,1.385368830001817,0.9010133357750852,1.6337001434401104,1.5930038530109396,0.3440786823573308,-0.19093998781040267,0.18851682862821462,-0.3603686262084453,0.028667653788611115,-0.2469724530743794,1.0819296780167726,0.001617352823824191,0.6900767143139638,0.8548449707097387,1.5520380971271386,-0.5337396628232933,0.2668410830881398,0.9239525336517246,0.6661166045339998,1.6539488897454098,-0.44656700343867023,-0.9224886791663648,1.4064557073170705,-0.3318542687573309,1.5520380971271386,-0.5630118383388776,-0.16309171563110678,1.3642073059600701,-0.3603686262084453,0.3440786823573308,0.2927084466196836,0.7376735390494176,1.059631974750273,1.2356247347543958,1.3429703349028668,1.1702575091989806,0.5199959431965512,-0.2469724530743794,0.3440786823573308,1.3429703349028668,0.7376735390494176,0.5935714761388575,-0.135356023882502,-0.5923906667876935,-0.3603686262084453,-0.8919614192603897,0.05560201529260138,0.10912089420536077,1.5725549938573544,0.42021400684349175,-0.27515574959433703,-1.0146826095408896,0.2668410830881398,-0.5923906667876935,1.2139174422855383,-0.025548389325393668,-0.3318542687573309,-1.1077876774028323,0.7376735390494176,0.6900767143139638,0.4703509047116417,-0.3889924804727667,0.9467966825508827,-0.05282908073775324,-0.025548389325393668,1.1041400729155888,0.9922045075089839,1.872502281604809,1.037245922867657,1.1041400729155888,0.8779778896871095,1.4692762530118126,0.49523405136401416,1.4484086529903741,0.544638339789795,0.05560201529260138,1.4692762530118126,1.5930038530109396,0.5935714761388575,1.2356247347543958,0.9010133357750852,1.8136359864985119,0.028667653788611115,1.32165710213149,0.7613131382611684,1.872502281604809,0.5935714761388575,0.7848487317778781,1.1262641794309365,0.49523405136401416,1.32165710213149,0.18851682862821462,-0.5630118383388776,0.2668410830881398,0.16216987090011553,1.1041400729155888,1.4692762530118126,0.3440786823573308,1.8333179734584413,0.7613131382611684,0.6178655297596958,2.7160278165306524,-0.8919614192603897,0.05560201529260138,-0.9224886791663648,0.9239525336517246,1.1702575091989806,1.2787985183948616,1.037245922867657,1.32165710213149,1.385368830001817,1.3642073059600701,1.5725549938573544,1.8920056904356866,1.8136359864985119,-0.3318542687573309,0.642046718499613,1.6539488897454098,-0.5045745330084603,-0.41772541135227015,0.642046718499613,-0.44656700343867023,0.2147447157493263,-0.44656700343867023,0.642046718499613,0.16216987090011553,0.028667653788611115,1.8136359864985119,-0.6514667327479815,0.5691629585556126,0.001617352823824191,-0.3889924804727667,1.9114506472351467,-0.5337396628232933,2.487824819755659,0.3184545058121038,-0.5045745330084603,0.5935714761388575,0.001617352823824191,0.544638339789795,-0.10773337464269757,0.18851682862821462,0.5199959431965512,0.42021400684349175,0.2927084466196836,-0.6514667327479815,0.6178655297596958,0.08241993256639264,-0.8919614192603897,0.10912089420536077,0.3695803896161305,-0.5923906667876935,0.16216987090011553,-0.3603686262084453,-0.3318542687573309,0.6900767143139638,0.5691629585556126,1.531452477522874,0.3695803896161305,-0.6514667327479815,0.2668410830881398,0.2927084466196836,0.2927084466196836,0.5935714761388575,0.028667653788611115,-0.3889924804727667,0.13570438202306856,0.08241993256639264,-0.30344983319990226,0.18851682862821462,-0.6514667327479815,0.08241993256639264,0.6661166045339998,0.9467966825508827,0.6900767143139638,1.852939889172417,0.16216987090011553,0.10912089420536077,0.3440786823573308,0.6900767143139638,0.8316133279582852,0.2668410830881398,0.3695803896161305,1.0819296780167726,0.7139285396999346,0.3695803896161305,1.037245922867657,-0.3318542687573309,0.3184545058121038,-0.6811632058277461,1.4692762530118126,1.1262641794309365
3,401
Nadh dehydrogenase complex assembly
9
26
3.102788
0.001917
O75306,P03886,Q15070,O95139,Q9Y6M9,Q9H061,Q16795,O43676,O43674
Processes and pathways
GO Biological process
msigdb_gobp
226,3,104,44,246,82,183,145,94
2498,94,145,974,226,2472,1705,44,248,838,1081,3,2380,366,104,2698,183,2407,993,822,82,1294,1545,929,830,246
-0.5045745330084603,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,-0.4755168460231504,-0.025548389325393668,2.6813851107199134,1.2787985183948616,0.49523405136401416,0.3184545058121038,4.544166984823674,-0.41772541135227015,0.9922045075089839,1.9114506472351467,-0.6218757596842738,1.4900722702883373,-0.41772541135227015,0.3949590324162235,0.5199959431965512,2.083908822428111,0.2147447157493263,0.08241993256639264,0.4453447000259606,0.5199959431965512,1.3002667781715258
3,401
Abnormal brainstem mri signal intensity
6
20
3.101769
0.001924
O75306,P03886,O95831,Q9Y6M9,O43676,Q9NPL8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,3,46,246,145,161
2498,145,974,226,292,1705,46,1081,3,2434,2380,2062,1325,2407,755,993,822,161,1545,246
-0.5045745330084603,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.025548389325393668,2.664001817387791,0.3184545058121038,4.544166984823674,-0.44656700343867023,-0.41772541135227015,-0.21890038394992256,0.18851682862821462,-0.41772541135227015,0.5691629585556126,0.3949590324162235,0.5199959431965512,1.6133853485657363,0.08241993256639264,1.3002667781715258
3,401
Water soluble vitamin metabolic process
8
20
3.100709
0.001931
P00374,Q969G6,P41440,Q9NRN7,Q9HC21,Q9NVS9,Q96RQ3,Q9H2D1
Processes and pathways
GO Biological process
msigdb_gobp
2,431,70,299,74,572,410,484
2,2685,1896,556,1562,70,1859,1164,2300,2490,1684,431,1346,410,1287,484,74,299,572,2367
5.0422806067498716,-0.6218757596842738,-0.135356023882502,0.7376735390494176,0.05560201529260138,2.177822330333986,-0.10773337464269757,0.2668410830881398,-0.3603686262084453,-0.4755168460231504,0.001617352823824191,0.9239525336517246,0.18851682862821462,0.9467966825508827,0.2147447157493263,0.8548449707097387,2.1404139980394676,1.1262641794309365,0.7376735390494176,-0.3889924804727667
3,401
Abnormal circulating carboxylic acid concentration
19
86
3.088088
0.002014
P03886,P22695,P00846,Q4G176,P05067,Q96RQ3,P48735,P00390,P55263,Q9Y619,O75880,Q6PGP7,Q9NVS9,P28288,Q5XKP0,P41440,O75845,Q14739,P23786
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,509,4,132,263,410,19,146,401,26,28,428,572,302,450,70,316,106,364
1655,553,2806,3051,316,28,1081,146,2051,4,3,2597,263,1364,2431,2375,1614,1661,1042,1512,2507,3008,1556,2432,1313,2781,3103,2474,1465,1368,1369,509,1211,364,3055,302,1515,910,2008,1470,2691,1715,2649,70,701,19,2113,1518,1126,401,1718,647,2612,1086,106,1680,2400,2699,132,2026,450,428,1387,1433,1822,1346,410,1287,1588,1289,2088,1745,2542,1350,572,929,2462,2276,2928,2325,1697,1653,794,2367,26,1755
0.001617352823824191,0.7376735390494176,-0.7408711516403494,-1.0456168391676224,1.0819296780167726,3.020731201810017,0.3184545058121038,1.6539488897454098,-0.21890038394992256,4.4328621068997585,4.544166984823674,-0.5630118383388776,1.2356247347543958,0.16216987090011553,-0.44656700343867023,-0.41772541135227015,0.028667653788611115,0.001617352823824191,0.3440786823573308,0.08241993256639264,-0.5045745330084603,-0.9531181920204688,0.05560201529260138,-0.44656700343867023,0.18851682862821462,-0.710964802828651,-1.139023630624162,-0.4755168460231504,0.10912089420536077,0.16216987090011553,0.16216987090011553,0.8082816835493837,0.2408529853896325,0.9922045075089839,-1.0456168391676224,1.1041400729155888,0.08241993256639264,0.4453447000259606,-0.19093998781040267,0.10912089420536077,-0.6218757596842738,-0.025548389325393668,-0.5923906667876935,2.177822330333986,0.5935714761388575,3.53430786323273,-0.2469724530743794,0.08241993256639264,0.2927084466196836,0.9467966825508827,-0.025548389325393668,0.642046718499613,-0.5630118383388776,0.3184545058121038,1.8920056904356866,0.001617352823824191,-0.41772541135227015,-0.6218757596842738,1.7342960667860914,-0.19093998781040267,0.9010133357750852,0.9239525336517246,0.16216987090011553,0.13570438202306856,-0.08022423571315228,0.18851682862821462,0.9467966825508827,0.2147447157493263,0.05560201529260138,0.2147447157493263,-0.21890038394992256,-0.025548389325393668,-0.5045745330084603,0.18851682862821462,0.7376735390494176,0.4453447000259606,-0.44656700343867023,-0.3318542687573309,-0.8312150461506137,-0.3603686262084453,0.001617352823824191,0.028667653788611115,0.544638339789795,-0.3889924804727667,3.053838714425047,-0.025548389325393668
3,401
Erythroid hypoplasia
12
20
3.086389
0.002026
P62847,P08708,P18077,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P62263,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,331,109,234,149,367,402,339,190,221
508,444,2992,221,331,2111,402,367,109,339,843,773,190,297,234,1327,1376,1052,149,591
0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.4692762530118126,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.7139285396999346
3,401
Abnormal mitochondria in muscle tissue
6
20
3.065183
0.002175
O75306,P00403,P03886,Q9Y6M9,O43676,Q9NPL8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,162,3,246,145,161
2498,145,974,226,292,1705,1081,162,3,2434,2380,1258,1325,2407,993,822,161,1545,2328,246
-0.5045745330084603,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.025548389325393668,0.3184545058121038,1.5930038530109396,4.544166984823674,-0.44656700343867023,-0.41772541135227015,0.2147447157493263,0.18851682862821462,-0.41772541135227015,0.3949590324162235,0.5199959431965512,1.6133853485657363,0.08241993256639264,-0.3603686262084453,1.3002667781715258
3,401
Carbohydrate derivative transport
12
20
3.059402
0.002218
O43808,P12235,P05141,P41440,Q9HC21,O00400,Q8TB61,Q99808,P12236,Q9NZJ7,Q96AA3,Q08722
Processes and pathways
GO Biological process
msigdb_gobp
35,253,537,70,74,11,140,274,462,285,159,63
552,11,1607,35,537,2643,253,462,70,3363,63,1057,2404,140,2705,1343,159,274,74,285
0.7376735390494176,3.8544190981954287,0.028667653788611115,2.8360067907741575,0.7613131382611684,-0.5923906667876935,1.2572514626291789,0.8779778896871095,2.177822330333986,-2.397336531738707,2.233550772463256,0.3440786823573308,-0.41772541135227015,1.6942507925226085,-0.6218757596842738,0.18851682862821462,1.6133853485657363,1.1921286759414857,2.1404139980394676,1.1702575091989806
3,401
Oxidoreductase
26
114
3.057173
0.002234
P00374,P03886,Q15392,P00390,O75880,Q15067,P00403,Q9UBM7,P14406,O75380,Q53FA7,O95831,O15254,Q8N8N7,Q16850,Q16795,O43169,O75845,O43674,O75306,Q00796,Q14739,Q9Y6M9,Q8N4Q0,P51970,O95168
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
2,3,7,146,28,404,162,39,163,292,426,46,418,49,53,183,69,316,94,226,101,106,246,375,366,248
2498,2426,666,1198,418,1548,69,2806,1460,94,419,1940,974,226,292,2472,316,28,2240,3347,248,46,1255,1158,536,2,146,162,3,2241,1707,2682,1613,1512,2507,1256,1557,2432,695,2781,2685,163,1896,3238,2559,907,1368,1119,1161,2721,2380,1856,1318,1619,3283,1258,489,1951,2291,910,2691,2649,2692,1771,2196,3395,2384,1901,1518,366,1958,1419,1218,101,2303,2567,846,1329,1781,106,2943,404,7,2573,2400,2698,183,53,2619,3198,426,888,990,375,49,2828,991,786,1736,993,2893,1738,3309,3170,1649,1294,1745,1597,572,2461,929,39,1749,246
-0.5045745330084603,-0.44656700343867023,0.6178655297596958,0.2408529853896325,0.9239525336517246,0.05560201529260138,2.177822330333986,-0.7408711516403494,0.10912089420536077,2.0078167090146146,0.9239525336517246,-0.16309171563110678,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,1.0819296780167726,3.020731201810017,-0.3318542687573309,-2.189703350368514,1.2787985183948616,2.664001817387791,0.2147447157493263,0.2668410830881398,0.7613131382611684,5.0422806067498716,1.6539488897454098,1.5930038530109396,4.544166984823674,-0.3318542687573309,-0.025548389325393668,-0.6218757596842738,0.028667653788611115,0.08241993256639264,-0.5045745330084603,0.2147447157493263,0.05560201529260138,-0.44656700343867023,0.5935714761388575,-0.710964802828651,-0.6218757596842738,1.5930038530109396,-0.135356023882502,-1.4891452293299312,-0.5337396628232933,0.4453447000259606,0.16216987090011553,0.2927084466196836,0.2668410830881398,-0.6514667327479815,-0.41772541135227015,-0.10773337464269757,0.18851682862821462,0.028667653788611115,-1.6850711931610414,0.2147447157493263,0.8316133279582852,-0.16309171563110678,-0.3603686262084453,0.4453447000259606,-0.6218757596842738,-0.5923906667876935,-0.6218757596842738,-0.05282908073775324,-0.30344983319990226,-4.445149495859484,-0.41772541135227015,-0.135356023882502,0.08241993256639264,0.9922045075089839,-0.16309171563110678,0.13570438202306856,0.2408529853896325,1.9501672914836015,-0.3603686262084453,-0.5337396628232933,0.49523405136401416,0.18851682862821462,-0.05282908073775324,1.8920056904356866,-0.8615367583845711,0.9467966825508827,4.133951074558761,-0.5337396628232933,-0.41772541135227015,-0.6218757596842738,1.4900722702883373,2.487824819755659,-0.5630118383388776,-1.3604554853890702,0.9239525336517246,0.4703509047116417,0.3949590324162235,0.9922045075089839,2.576453896227463,-0.7408711516403494,0.3949590324162235,0.544638339789795,-0.025548389325393668,0.3949590324162235,-0.8009966357602808,-0.025548389325393668,-1.784318714613512,-1.2966959112582077,0.028667653788611115,0.2147447157493263,-0.025548389325393668,0.05560201529260138,0.7376735390494176,-0.44656700343867023,0.4453447000259606,2.8019254667161024,-0.025548389325393668,1.3002667781715258
3,401
Complex i biogenesis
10
28
3.029482
0.00245
O75306,P03886,O75380,O95139,Q9Y6M9,Q16795,O43676,O95168,O43674,Q9NPL8
Processes and pathways
Reactome Pathways
msigdb_reactome
226,3,292,44,246,183,145,248,94,161
2498,94,145,974,226,292,2472,1705,44,248,1999,838,1081,3,2434,2380,1325,366,2698,183,2407,1593,822,1294,161,1545,929,246
-0.5045745330084603,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,4.544166984823674,-0.44656700343867023,-0.41772541135227015,0.18851682862821462,0.9922045075089839,-0.6218757596842738,1.4900722702883373,-0.41772541135227015,0.05560201529260138,0.5199959431965512,0.2147447157493263,1.6133853485657363,0.08241993256639264,0.4453447000259606,1.3002667781715258
3,401
Organic acid transport
20
46
3.018208
0.002543
P53985,Q9Y619,P53007,P14174,P21359,O43808,Q15041,Q13131,O43772,P28288,P41440,O60831,Q02978,P30825,Q9H2D1,P08183,Q9H936,Q9UBX3,Q6P4A7,P23786
Processes and pathways
GO Biological process
msigdb_gobp
133,26,400,29,287,35,37,425,47,302,70,202,332,88,484,338,359,121,514,364
2332,1607,47,35,202,872,837,506,2596,2337,2002,2242,1765,338,2003,29,287,364,302,3085,88,1857,1418,70,2786,400,133,1809,332,425,37,1524,2790,1866,514,2705,894,3114,484,1233,359,1692,121,1697,2233,26
-0.3889924804727667,0.028667653788611115,2.629109857257126,2.8360067907741575,1.4064557073170705,0.4703509047116417,0.49523405136401416,0.8082816835493837,-0.5630118383388776,-0.3889924804727667,-0.19093998781040267,-0.3318542687573309,-0.05282908073775324,1.037245922867657,-0.19093998781040267,2.9874793053049182,1.1483029978313013,0.9922045075089839,1.1041400729155888,-1.1077876774028323,2.0459717130687864,-0.10773337464269757,0.13570438202306856,2.177822330333986,-0.710964802828651,0.9467966825508827,1.7143052013527764,-0.08022423571315228,1.059631974750273,0.9239525336517246,2.8189856921283467,0.08241993256639264,-0.710964802828651,-0.10773337464269757,0.8082816835493837,-0.6218757596842738,0.4703509047116417,-1.139023630624162,0.8548449707097387,0.2408529853896325,1.014770461288004,0.001617352823824191,1.8136359864985119,0.001617352823824191,-0.30344983319990226,3.053838714425047
3,401
Muscle abnormality related to mitochondrial dysfunction
12
36
3.008271
0.002627
O75306,P00403,P03886,P00846,P12235,Q9Y606,O75380,Q9Y6M9,O43676,Q9UBX3,Q9Y2R0,Q9NPL8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,162,3,4,253,269,292,246,145,121,24,161
2498,666,145,2747,974,226,292,1705,3051,1081,162,4,3,253,2434,2380,1807,1325,1259,1126,2078,2407,2949,993,895,1442,822,311,1981,161,1545,121,24,1032,269,246
-0.5045745330084603,0.6178655297596958,1.6539488897454098,-0.6811632058277461,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.025548389325393668,-1.0456168391676224,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,1.2572514626291789,-0.44656700343867023,-0.41772541135227015,-0.08022423571315228,0.18851682862821462,0.2147447157493263,0.2927084466196836,-0.21890038394992256,-0.41772541135227015,-0.8615367583845711,0.3949590324162235,0.4703509047116417,0.13570438202306856,0.5199959431965512,1.1041400729155888,-0.16309171563110678,1.6133853485657363,0.08241993256639264,1.8136359864985119,3.2334307204873185,0.3695803896161305,1.2139174422855383,1.3002667781715258
3,401
Reduced consciousness confusion
39
125
3.003461
0.002669
P03886,P08708,P12235,P05067,Q96RQ3,Q07020,O43676,O14802,Q9NZJ7,Q9UHD2,Q9Y619,P60866,Q9NPL8,P35610,P00403,P00367,P62847,Q9UBM7,O75380,O43772,P26358,O43819,P19447,Q9NWS8,P18077,Q9HC21,P46777,P61353,P40818,P42766,O75306,Q9H936,P08397,P61313,P62854,Q9Y6M9,Q5U5X0,P61254,P23786
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,508,253,263,410,149,145,525,285,551,26,402,161,157,162,536,297,39,292,47,176,419,554,597,444,74,331,339,220,221,226,359,232,109,234,246,491,367,364
795,2498,3310,525,145,1995,47,419,974,226,292,1705,1081,1799,536,162,1309,3,873,263,1364,2431,2643,232,1661,508,2507,1556,1557,253,2781,444,2434,554,1368,1369,364,2810,176,2721,2380,2647,1857,2247,1515,157,1319,1858,910,2754,2691,2992,2756,220,1214,2058,221,1808,2294,331,2111,1324,2384,1472,2062,1325,1124,2786,1861,402,367,109,339,843,773,297,234,1327,1376,1052,149,1962,651,1329,1630,3045,2400,1383,491,2407,2863,1227,2454,1822,591,3243,993,1346,1686,410,895,3000,3226,822,359,2134,74,2542,161,2225,597,2177,1836,285,1545,39,551,1697,3066,3387,1107,794,26,1755,246
0.5199959431965512,-0.5045745330084603,-1.8175896931885265,0.7848487317778781,1.6539488897454098,-0.19093998781040267,2.629109857257126,0.9239525336517246,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.025548389325393668,0.3184545058121038,-0.08022423571315228,0.7613131382611684,1.5930038530109396,0.18851682862821462,4.544166984823674,0.4703509047116417,1.2356247347543958,0.16216987090011553,-0.44656700343867023,-0.5923906667876935,1.32165710213149,0.001617352823824191,0.8082816835493837,-0.5045745330084603,0.05560201529260138,0.05560201529260138,1.2572514626291789,-0.710964802828651,0.9010133357750852,-0.44656700343867023,0.7376735390494176,0.16216987090011553,0.16216987090011553,0.9922045075089839,-0.7408711516403494,1.531452477522874,-0.6514667327479815,-0.41772541135227015,-0.5923906667876935,-0.10773337464269757,-0.3318542687573309,0.08241993256639264,1.6133853485657363,0.18851682862821462,-0.10773337464269757,0.4453447000259606,-0.6811632058277461,-0.6218757596842738,-0.9224886791663648,-0.6811632058277461,1.3642073059600701,0.2408529853896325,-0.21890038394992256,1.3642073059600701,-0.08022423571315228,-0.3603686262084453,1.059631974750273,-0.2469724530743794,0.18851682862821462,-0.41772541135227015,0.10912089420536077,-0.21890038394992256,0.18851682862821462,0.2927084466196836,-0.710964802828651,-0.10773337464269757,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,-0.16309171563110678,0.642046718499613,0.18851682862821462,0.028667653788611115,-1.0146826095408896,-0.41772541135227015,0.16216987090011553,0.8316133279582852,-0.41772541135227015,-0.7708818840672291,0.2408529853896325,-0.44656700343867023,-0.08022423571315228,0.7139285396999346,-1.4891452293299312,0.3949590324162235,0.18851682862821462,0.001617352823824191,0.9467966825508827,0.4703509047116417,-0.9224886791663648,-1.4246060531713614,0.5199959431965512,1.014770461288004,-0.2469724530743794,2.1404139980394676,-0.5045745330084603,1.6133853485657363,-0.30344983319990226,0.7139285396999346,-0.27515574959433703,-0.08022423571315228,1.1702575091989806,0.08241993256639264,2.8019254667161024,0.7613131382611684,0.001617352823824191,-1.0456168391676224,-3.2596380799554647,0.3184545058121038,0.544638339789795,3.053838714425047,-0.025548389325393668,1.3002667781715258
3,401
Anion transmembrane transport
22
44
2.997623
0.002721
P12235,P53985,O95563,Q8TB61,Q9Y619,P53007,O43808,Q15041,P45880,P41440,Q9Y277,Q9HC21,O60831,Q02978,P12236,P30825,Q9UHG3,Q9H2D1,P08183,Q9H936,P21796,Q9UBX3
Processes and pathways
GO Biological process
msigdb_gobp
253,133,506,140,26,400,35,37,295,70,72,74,202,332,462,88,91,484,338,359,240,121
1607,35,202,872,837,506,1801,537,2242,338,2003,253,462,240,88,70,295,2198,3320,1217,400,133,1809,741,332,37,2790,2355,140,2705,894,1445,484,359,1692,74,3021,121,91,1697,72,724,26,866
0.028667653788611115,2.8360067907741575,1.4064557073170705,0.4703509047116417,0.49523405136401416,0.8082816835493837,-0.08022423571315228,0.7613131382611684,-0.3318542687573309,1.037245922867657,-0.19093998781040267,1.2572514626291789,0.8779778896871095,1.3002667781715258,2.0459717130687864,2.177822330333986,1.1262641794309365,-0.30344983319990226,-1.884412751971023,0.2408529853896325,0.9467966825508827,1.7143052013527764,-0.08022423571315228,0.5691629585556126,1.059631974750273,2.8189856921283467,-0.710964802828651,-0.3889924804727667,1.6942507925226085,-0.6218757596842738,0.4703509047116417,0.13570438202306856,0.8548449707097387,1.014770461288004,0.001617352823824191,2.1404139980394676,-0.9531181920204688,1.8136359864985119,2.0459717130687864,0.001617352823824191,2.1591440513142732,0.5935714761388575,3.053838714425047,0.49523405136401416
3,401
Mitochondrial complex i assembly model oxphos system
9
27
2.996124
0.002734
O75306,P03886,O75380,O95139,Q9Y6M9,O43676,O95168,O43674,Q9NPL8
Processes and pathways
WikiPathways
msigdb_wp
226,3,292,44,246,145,248,94,161
94,145,226,292,2472,1705,44,248,1999,838,1081,3,2434,2380,1325,366,2698,2407,993,1593,822,1289,1294,161,1545,929,246
2.0078167090146146,1.6539488897454098,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,4.544166984823674,-0.44656700343867023,-0.41772541135227015,0.18851682862821462,0.9922045075089839,-0.6218757596842738,-0.41772541135227015,0.3949590324162235,0.05560201529260138,0.5199959431965512,0.2147447157493263,0.2147447157493263,1.6133853485657363,0.08241993256639264,0.4453447000259606,1.3002667781715258
3,401
Nadh dehydrogenase complex
9
24
2.993897
0.002754
O75306,P03886,O75380,O95139,Q9Y6M9,Q16795,O43676,O95168,O43674
Localization
GO Cellular component
msigdb_gocc
226,3,292,44,246,183,145,248,94
2498,666,94,145,974,226,292,2472,1705,44,248,1999,838,1081,3,2434,2380,1325,366,2698,183,993,929,246
-0.5045745330084603,0.6178655297596958,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,4.544166984823674,-0.44656700343867023,-0.41772541135227015,0.18851682862821462,0.9922045075089839,-0.6218757596842738,1.4900722702883373,0.3949590324162235,0.4453447000259606,1.3002667781715258
3,401
Energy derivation by oxidation of organic compounds
32
126
2.973255
0.002947
P03886,P22695,P00846,Q6P444,Q9H3K2,P48735,Q04446,O43676,Q9BSK2,P00403,P14406,O95139,Q9NZ45,O75964,O75380,O43819,Q16795,P61586,O75874,P56134,P46976,P24539,P13073,O43674,O75306,Q9H936,Q15070,Q9Y6M9,P30405,Q5U5X0,P51970,O95168
Processes and pathways
GO Biological process
msigdb_gobp
3,509,4,385,13,19,530,145,32,162,163,44,45,168,292,419,183,423,61,446,319,71,463,94,226,359,104,246,488,491,366,248
2498,666,1198,94,145,419,1940,974,226,975,292,1555,2472,1705,872,61,2808,168,44,248,1999,838,1081,162,4,3,873,2241,2964,671,2849,601,2375,1614,1661,1850,2507,939,2555,1256,2556,2645,1557,463,2781,1011,163,619,1315,3238,907,3143,2434,1368,2106,1119,2245,509,71,3055,1804,2380,488,1213,1258,1857,733,1562,734,1014,1621,2755,2691,2649,2692,539,1321,1771,319,2383,19,2384,1325,943,1901,366,1126,2942,446,2255,423,1568,1906,1677,530,776,2789,1329,104,2996,743,2400,2698,183,2484,491,1057,956,385,783,2949,3138,2413,2221,1792,32,1981,13,359,1187,45,1694,2462,1697,3050,246
-0.5045745330084603,0.6178655297596958,0.2408529853896325,2.0078167090146146,1.6539488897454098,0.9239525336517246,-0.16309171563110678,0.3949590324162235,1.3429703349028668,0.3949590324162235,1.1262641794309365,0.05560201529260138,-0.4755168460231504,-0.025548389325393668,0.4703509047116417,2.2520261761745286,-0.7408711516403494,1.5725549938573544,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,0.4703509047116417,-0.3318542687573309,-0.8919614192603897,0.6178655297596958,-0.7708818840672291,0.6900767143139638,-0.41772541135227015,0.028667653788611115,0.001617352823824191,-0.10773337464269757,-0.5045745330084603,0.42021400684349175,-0.5337396628232933,0.2147447157493263,-0.5337396628232933,-0.5923906667876935,0.05560201529260138,0.8779778896871095,-0.710964802828651,0.3695803896161305,1.5930038530109396,0.6661166045339998,0.18851682862821462,-1.4891452293299312,0.4453447000259606,-1.233329760418191,-0.44656700343867023,0.16216987090011553,-0.2469724530743794,0.2927084466196836,-0.3318542687573309,0.8082816835493837,2.1591440513142732,-1.0456168391676224,-0.08022423571315228,-0.41772541135227015,0.8316133279582852,0.2408529853896325,0.2147447157493263,-0.10773337464269757,0.5691629585556126,0.05560201529260138,0.5691629585556126,0.3695803896161305,0.028667653788611115,-0.6811632058277461,-0.6218757596842738,-0.5923906667876935,-0.6218757596842738,0.7613131382611684,0.18851682862821462,-0.05282908073775324,1.0819296780167726,-0.41772541135227015,3.53430786323273,-0.41772541135227015,0.18851682862821462,0.42021400684349175,-0.135356023882502,0.9922045075089839,0.2927084466196836,-0.8615367583845711,0.9010133357750852,-0.3318542687573309,0.9239525336517246,0.05560201529260138,-0.135356023882502,0.001617352823824191,0.7848487317778781,0.544638339789795,-0.710964802828651,0.18851682862821462,1.9114506472351467,-0.9224886791663648,0.5691629585556126,-0.41772541135227015,-0.6218757596842738,1.4900722702883373,-0.4755168460231504,0.8316133279582852,0.3440786823573308,0.42021400684349175,0.9695469569963517,0.544638339789795,-0.8615367583845711,-1.201794990466699,-0.41772541135227015,-0.30344983319990226,-0.05282908073775324,2.9540811147426025,-0.16309171563110678,3.6882822134218296,1.014770461288004,0.2668410830881398,2.6813851107199134,0.001617352823824191,-0.44656700343867023,0.001617352823824191,-1.0146826095408896,1.3002667781715258
3,401
Influenza infection
53
128
2.972433
0.002954
P08708,P46778,P62277,Q07020,P62841,P36578,P60866,P18124,P46781,P62750,P63173,P18621,P62266,P62847,P84098,P50914,P27635,P40429,P32969,P62906,P46776,P61247,P61513,P49207,P62263,P62910,Q9Y3U8,P62280,P61927,P62241,P26373,P18077,P46777,P39023,P12236,P83731,P15880,P13984,P61353,P83881,P42766,P46779,P47914,Q02543,P61313,P62753,P62701,P62854,P62917,Q02878,P61254,P62424,P52434
Processes and pathways
Reactome Pathways
msigdb_reactome
508,264,265,149,529,148,402,154,279,540,541,164,165,297,171,169,174,175,422,308,557,306,307,558,190,191,192,447,189,195,317,444,331,205,462,217,215,214,339,222,221,227,228,105,109,110,233,234,113,119,367,118,123
933,1505,1889,833,1199,2844,2780,3007,1709,2598,508,2149,3219,1895,462,3220,214,215,444,154,164,2991,2939,1713,1317,2852,2108,317,174,3290,2512,1162,1468,422,621,3252,2515,148,2690,2992,205,175,221,557,331,264,227,279,801,2111,228,558,3010,2062,169,2440,2854,123,2607,2441,402,306,367,109,339,307,189,843,195,773,1569,190,165,705,265,447,118,2390,233,540,110,805,706,529,297,844,234,1327,2608,2068,1169,1376,308,191,1052,113,541,678,2884,217,222,171,1627,105,119,149,1520,2158,1908,2617,607,3232,2530,2862,2621,1061,3397,3203,2622,590,1922,3226,1443,3270,2037,2364,2897,192
0.42021400684349175,0.08241993256639264,-0.135356023882502,0.49523405136401416,0.2408529853896325,-0.7708818840672291,-0.710964802828651,-0.9531181920204688,-0.025548389325393668,-0.5630118383388776,0.8082816835493837,-0.27515574959433703,-1.4246060531713614,-0.135356023882502,0.8779778896871095,-1.4246060531713614,1.385368830001817,1.385368830001817,0.9010133357750852,1.6337001434401104,1.5930038530109396,-0.9224886791663648,-0.8615367583845711,-0.025548389325393668,0.18851682862821462,-0.7708818840672291,-0.2469724530743794,1.0819296780167726,1.5520380971271386,-1.7180591941474048,-0.5045745330084603,0.2668410830881398,0.10912089420536077,0.9239525336517246,0.6661166045339998,-1.5540706716205697,-0.5045745330084603,1.6539488897454098,-0.6218757596842738,-0.9224886791663648,1.4064557073170705,1.5520380971271386,1.3642073059600701,0.7376735390494176,1.059631974750273,1.2356247347543958,1.3429703349028668,1.1702575091989806,0.5199959431965512,-0.2469724530743794,1.3429703349028668,0.7376735390494176,-0.9531181920204688,-0.21890038394992256,1.5725549938573544,-0.44656700343867023,-0.7708818840672291,1.7938933718647914,-0.5630118383388776,-0.44656700343867023,0.9467966825508827,1.1041400729155888,0.9922045075089839,1.872502281604809,1.037245922867657,1.1041400729155888,1.4692762530118126,0.49523405136401416,1.4484086529903741,0.544638339789795,0.05560201529260138,1.4692762530118126,1.5930038530109396,0.5935714761388575,1.2356247347543958,0.9010133357750852,1.8136359864985119,-0.41772541135227015,1.32165710213149,0.7613131382611684,1.872502281604809,0.5199959431965512,0.5935714761388575,0.7848487317778781,1.1262641794309365,0.49523405136401416,1.32165710213149,0.18851682862821462,-0.5630118383388776,-0.21890038394992256,0.2668410830881398,0.16216987090011553,1.1041400729155888,1.4692762530118126,0.3440786823573308,1.8333179734584413,0.7613131382611684,0.6178655297596958,-0.8009966357602808,1.385368830001817,1.3642073059600701,1.5725549938573544,0.028667653788611115,1.8920056904356866,1.8136359864985119,1.6539488897454098,0.08241993256639264,-0.27515574959433703,-0.135356023882502,-0.5630118383388776,0.6900767143139638,-1.4568272125871744,-0.5045745330084603,-0.7708818840672291,-0.5630118383388776,0.3440786823573308,-5.74858942686859,-1.3604554853890702,-0.5630118383388776,0.7139285396999346,-0.135356023882502,-1.4246060531713614,0.13570438202306856,-1.6193800795521127,-0.19093998781040267,-0.3889924804727667,-0.8009966357602808,1.4692762530118126
3,401
Mitotic g1 phase and g1 s transition
24
82
2.952597
0.003151
P28070,P00374,Q13309,P35244,Q9Y619,P06493,P49720,P28074,Q9UBD5,P28072,P49721,Q14181,P20248,O43242,Q9NR33,P24941,O43913,Q00534,Q07864,P20618,P31350,O75832,P25786,P14635
Processes and pathways
Reactome Pathways
msigdb_reactome
255,2,510,147,26,671,296,59,721,194,67,321,445,329,79,464,213,341,606,103,489,487,620,619
1504,2046,1034,1604,2237,329,213,3101,487,2,874,1310,671,2599,2376,2937,839,2684,619,906,2753,445,103,464,2007,620,1666,977,909,1948,1416,255,194,59,1212,698,489,1857,2342,1620,1953,147,1954,1085,2110,1622,1163,1216,296,67,2061,1672,1810,1474,803,2011,1720,1959,1375,1377,1017,341,2305,606,1572,510,1477,2159,1479,321,2483,1018,2922,790,1494,79,2136,721,1696,1301,1457,26
0.08241993256639264,-0.21890038394992256,0.3440786823573308,0.028667653788611115,-0.3318542687573309,1.059631974750273,1.385368830001817,-1.139023630624162,0.8316133279582852,5.0422806067498716,0.4703509047116417,0.18851682862821462,0.6178655297596958,-0.5630118383388776,-0.41772541135227015,-0.8615367583845711,0.49523405136401416,-0.6218757596842738,0.6661166045339998,0.4453447000259606,-0.6811632058277461,0.9010133357750852,1.930837675632946,0.8779778896871095,-0.19093998781040267,0.6661166045339998,0.001617352823824191,0.3949590324162235,0.4453447000259606,-0.16309171563110678,0.13570438202306856,1.2572514626291789,1.4484086529903741,2.270451887980421,0.2408529853896325,0.5935714761388575,0.8316133279582852,-0.10773337464269757,-0.3889924804727667,0.028667653788611115,-0.16309171563110678,1.6539488897454098,-0.16309171563110678,0.3184545058121038,-0.2469724530743794,0.028667653788611115,0.2668410830881398,0.2408529853896325,1.1262641794309365,2.1964492630808774,-0.21890038394992256,0.001617352823824191,-0.08022423571315228,0.10912089420536077,0.5199959431965512,-0.19093998781040267,-0.025548389325393668,-0.16309171563110678,0.16216987090011553,0.16216987090011553,0.3695803896161305,1.037245922867657,-0.3603686262084453,0.6900767143139638,0.05560201529260138,0.8082816835493837,0.10912089420536077,-0.27515574959433703,0.10912089420536077,1.0819296780167726,-0.4755168460231504,0.3695803896161305,-0.8312150461506137,0.544638339789795,0.10912089420536077,2.1216317365456785,-0.2469724530743794,0.5935714761388575,0.001617352823824191,0.2147447157493263,0.13570438202306856,3.053838714425047
3,401
kinase
7
20
2.941026
0.003271
Q9HBU6,Q9NVE7,P35790,Q8WVC6,Q9BTU6,Q9HA64,Q8TBX8
Functions
Panther Protein class
panther_protein_class
136,333,14,207,242,211,124
1113,1712,1083,1465,940,14,2344,1372,1267,1221,2078,124,207,454,242,211,136,3126,333,1299
0.2927084466196836,-0.025548389325393668,0.3184545058121038,0.10912089420536077,0.42021400684349175,3.642391628326361,-0.3889924804727667,0.16216987090011553,0.2147447157493263,0.2408529853896325,-0.21890038394992256,1.7938933718647914,1.4064557073170705,0.9010133357750852,1.3002667781715258,1.4064557073170705,1.7143052013527764,-1.1703595082645744,1.059631974750273,0.2147447157493263
3,401
Mitochondrial electron transport nadh to ubiquinone
9
25
2.935928
0.003326
O75306,P03886,O75380,O95139,Q9Y6M9,Q16795,O43676,O95168,O43674
Processes and pathways
GO Biological process
msigdb_gobp
226,3,292,44,246,183,145,248,94
2498,666,94,145,974,226,292,2472,1705,44,248,1999,838,1081,3,2507,2434,2380,1325,366,2698,183,2413,1981,246
-0.5045745330084603,0.6178655297596958,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,4.544166984823674,-0.5045745330084603,-0.44656700343867023,-0.41772541135227015,0.18851682862821462,0.9922045075089839,-0.6218757596842738,1.4900722702883373,-0.41772541135227015,-0.16309171563110678,1.3002667781715258
3,401
Nadp binding
6
20
2.933993
0.003346
P00374,Q9UBM7,Q53FA7,Q14739,P00390,O75874
Functions
GO Molecular function
msigdb_gomf
2,39,426,106,146,61
61,2,146,443,1707,1512,2432,2509,1951,1515,2883,1958,1961,1329,106,3198,426,2275,39,1749
2.2520261761745286,5.0422806067498716,1.6539488897454098,0.9010133357750852,-0.025548389325393668,0.08241993256639264,-0.44656700343867023,-0.5045745330084603,-0.16309171563110678,0.08241993256639264,-0.8009966357602808,-0.16309171563110678,-0.16309171563110678,0.18851682862821462,1.8920056904356866,-1.3604554853890702,0.9239525336517246,-0.3318542687573309,2.8019254667161024,-0.025548389325393668
3,401
Cytosolic small ribosomal subunit
22
32
2.921595
0.003482
Q7Z478,P08708,P62277,P62244,P62841,P60866,P82912,P46781,P62266,P62847,P63220,P46782,P61247,P62263,P62280,P62241,P62269,P15880,P62081,P62854,P62753,P62701
Localization
GO Cellular component
msigdb_gocc
657,508,265,773,529,402,280,279,165,297,678,801,306,190,447,195,705,215,843,234,110,233
2148,508,2149,215,1317,2108,2992,279,801,2111,402,306,843,195,773,1569,190,165,705,265,447,233,110,529,297,844,234,1327,678,280,657,1290
-0.27515574959433703,0.8082816835493837,-0.27515574959433703,1.385368830001817,0.18851682862821462,-0.2469724530743794,-0.9224886791663648,1.1702575091989806,0.5199959431965512,-0.2469724530743794,0.9467966825508827,1.1041400729155888,0.49523405136401416,1.4484086529903741,0.544638339789795,0.05560201529260138,1.4692762530118126,1.5930038530109396,0.5935714761388575,1.2356247347543958,0.9010133357750852,1.32165710213149,1.872502281604809,0.7848487317778781,1.1262641794309365,0.49523405136401416,1.32165710213149,0.18851682862821462,0.6178655297596958,1.1702575091989806,0.642046718499613,0.2147447157493263
3,401
Activation of gene expression by srebf srebp
7
20
2.911227
0.0036
Q15648,O75845,Q9UBM7,O00767,Q9HCL2,Q16850,P48449
Processes and pathways
Reactome Pathways
msigdb_reactome
357,316,39,138,111,53,125
2776,138,316,443,1464,2008,125,1324,2693,984,680,1523,1781,357,53,1021,2584,1742,111,39
-0.710964802828651,1.6942507925226085,1.0819296780167726,0.9010133357750852,0.10912089420536077,-0.19093998781040267,1.7740895644817878,0.18851682862821462,-0.6218757596842738,0.3949590324162235,0.6178655297596958,0.08241993256639264,-0.05282908073775324,1.014770461288004,2.487824819755659,0.3695803896161305,-0.5337396628232933,-0.025548389325393668,1.852939889172417,2.8019254667161024
3,401
Adenocarcinoma of the colon
12
21
2.911146
0.003601
P62847,P08708,P18077,Q969E8,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,591,331,109,234,149,367,402,339,221
508,444,1257,2992,221,331,2111,402,367,109,339,843,773,297,234,1327,1376,1052,149,606,591
0.8082816835493837,0.9010133357750852,0.2147447157493263,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.6900767143139638,0.7139285396999346
3,401
Anion transmembrane transporter activity
22
49
2.894243
0.003801
P12235,P53985,O95563,O00400,Q8TB61,Q99808,Q9Y619,P53007,P0CG08,O43808,P45880,P41440,Q9Y277,Q9HC21,Q02978,P12236,Q9C0H2,P30825,Q9H2D1,Q9H936,P21796,Q9UBX3
Functions
GO Molecular function
msigdb_gomf
253,133,506,11,140,274,26,400,278,35,295,70,72,74,332,462,347,88,484,359,240,121
2187,11,2332,1607,1995,35,872,506,1801,537,2003,278,253,462,240,88,70,295,2198,3320,1217,400,133,1809,332,655,2790,2355,1057,2404,1866,140,2705,894,1643,274,1445,347,484,359,1692,74,3271,121,1697,72,26,1111,866
-0.30344983319990226,3.8544190981954287,-0.3889924804727667,0.028667653788611115,-0.19093998781040267,2.8360067907741575,0.4703509047116417,0.8082816835493837,-0.08022423571315228,0.7613131382611684,-0.19093998781040267,1.1702575091989806,1.2572514626291789,0.8779778896871095,1.3002667781715258,2.0459717130687864,2.177822330333986,1.1262641794309365,-0.30344983319990226,-1.884412751971023,0.2408529853896325,0.9467966825508827,1.7143052013527764,-0.08022423571315228,1.059631974750273,0.642046718499613,-0.710964802828651,-0.3889924804727667,0.3440786823573308,-0.41772541135227015,-0.10773337464269757,1.6942507925226085,-0.6218757596842738,0.4703509047116417,0.028667653788611115,1.1921286759414857,0.13570438202306856,1.037245922867657,0.8548449707097387,1.014770461288004,0.001617352823824191,2.1404139980394676,-1.6193800795521127,1.8136359864985119,0.001617352823824191,2.1591440513142732,3.053838714425047,0.3184545058121038,0.49523405136401416
3,401
Persistence of hemoglobin f
11
22
2.893016
0.003816
P62847,P08708,P18077,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,331,109,234,149,367,402,339,221
508,444,2992,221,331,2111,402,1718,367,109,339,843,773,297,234,1327,1376,1052,149,2026,591,1653
0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,-0.025548389325393668,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,-0.19093998781040267,0.7139285396999346,0.028667653788611115
3,401
Cholesterol biosynthesis
6
16
2.889112
0.003863
Q15392,O75845,Q9UBM7,Q14739,Q16850,P48449
Processes and pathways
Reactome Pathways
msigdb_reactome
7,316,39,106,53,125
316,443,1464,2008,125,2693,984,1523,1781,106,7,1270,2573,53,2323,39
1.0819296780167726,0.9010133357750852,0.10912089420536077,-0.19093998781040267,1.7740895644817878,-0.6218757596842738,0.3949590324162235,0.08241993256639264,-0.05282908073775324,1.8920056904356866,4.133951074558761,0.2147447157493263,-0.5337396628232933,2.487824819755659,-0.3603686262084453,2.8019254667161024
3,401
Reticulocytopenia
14
21
2.87026
0.004101
P62847,P08708,Q9BXW9,P18077,Q969E8,P46777,P61313,P62854,P62244,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,762,444,591,331,109,234,773,149,367,402,339,221
508,444,2992,221,331,2111,402,367,109,339,843,773,297,234,1327,1376,1052,149,591,762,1653
0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.7139285396999346,0.5691629585556126,0.028667653788611115
3,401
Mitochondrial transport
23
91
2.854659
0.004308
P00846,P12235,P19784,Q8N8Q8,Q07812,P05141,P45880,P55786,Q13131,O75964,O95831,O43772,P30536,P56134,P24539,O95429,O60830,P62072,Q15070,Q9Y584,P30405,Q9UBX3,P23786
Processes and pathways
GO Biological process
msigdb_gobp
4,253,270,143,289,537,295,170,425,168,46,47,294,446,71,203,458,93,104,245,488,121,364
1112,900,1757,1606,1361,47,2099,458,2749,1892,2808,168,2504,1117,203,2906,46,1799,4,2964,537,2849,2598,1206,3193,253,3143,270,364,71,3055,488,1371,294,2688,1621,2059,295,2383,1859,1323,943,2786,583,1372,170,446,2255,93,1777,289,1054,425,104,1816,2822,1093,2078,1273,2404,1096,2124,1434,143,2665,2314,570,1586,3000,2035,1588,2416,2835,2137,2226,929,1985,1794,121,2956,1697,3050,830,3355,2233,2184,1149,245,1503,832,1302
0.2927084466196836,0.4453447000259606,-0.05282908073775324,0.028667653788611115,0.16216987090011553,2.629109857257126,-0.2469724530743794,0.8779778896871095,-0.6811632058277461,-0.135356023882502,-0.7408711516403494,1.5725549938573544,-0.5045745330084603,0.2927084466196836,1.4064557073170705,-0.8312150461506137,2.664001817387791,-0.08022423571315228,4.4328621068997585,-0.8919614192603897,0.7613131382611684,-0.7708818840672291,-0.5630118383388776,0.2408529853896325,-1.3604554853890702,1.2572514626291789,-1.233329760418191,1.1921286759414857,0.9922045075089839,2.1591440513142732,-1.0456168391676224,0.8316133279582852,0.16216987090011553,1.1262641794309365,-0.6218757596842738,0.028667653788611115,-0.21890038394992256,1.1262641794309365,-0.41772541135227015,-0.10773337464269757,0.18851682862821462,0.42021400684349175,-0.710964802828651,0.7139285396999346,0.16216987090011553,1.5725549938573544,0.9010133357750852,-0.3318542687573309,2.0269216832537302,-0.05282908073775324,1.1483029978313013,0.3440786823573308,0.9239525336517246,1.9114506472351467,-0.08022423571315228,-0.7408711516403494,0.3184545058121038,-0.21890038394992256,0.2147447157493263,-0.41772541135227015,0.3184545058121038,-0.2469724530743794,0.13570438202306856,1.6741322290310687,-0.5923906667876935,-0.3603686262084453,0.7376735390494176,0.05560201529260138,-0.9224886791663648,-0.19093998781040267,0.05560201529260138,-0.41772541135227015,-0.7408711516403494,-0.2469724530743794,-0.30344983319990226,0.4453447000259606,-0.16309171563110678,-0.05282908073775324,1.8136359864985119,-0.8615367583845711,0.001617352823824191,-1.0146826095408896,0.5199959431965512,-2.2240827955771967,-0.30344983319990226,-0.27515574959433703,0.2927084466196836,1.3002667781715258,0.10912089420536077,0.5199959431965512,0.2147447157493263
3,401
Abnormality of the thenar eminence
11
19
2.843695
0.004459
P62847,P08708,P18077,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,331,109,234,149,367,402,339,221
508,444,2992,221,331,2111,402,367,109,339,843,773,297,234,1327,1376,1052,149,591
0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.7139285396999346
3,401
Active transmembrane transporter activity
24
79
2.843474
0.004462
P03886,P53985,P12235,O00400,O43676,P53007,Q9HD20,P00403,O95202,O95139,O75380,Q16795,P28288,P41440,Q02978,P13073,P08183,O43674,O75306,Q9H936,Q9Y6M9,Q9UBX3,P51970,O95168
Functions
GO Molecular function
msigdb_gomf
3,133,253,11,145,400,160,162,293,44,292,183,302,70,332,463,338,94,226,359,246,121,366,248
2498,11,666,1198,1607,94,145,1843,974,226,292,2472,1705,44,248,1999,293,838,1081,162,3,1801,2052,2848,537,2849,338,2003,1850,1256,253,462,463,908,2434,2687,1368,1766,2510,2006,302,2380,733,1319,2562,2784,70,1325,2198,3320,1217,366,400,133,1809,2389,3277,741,332,3350,655,1816,2790,2698,183,783,1974,1445,1233,359,160,3171,2137,929,121,1356,1109,866,246
-0.5045745330084603,3.8544190981954287,0.6178655297596958,0.2408529853896325,0.028667653788611115,2.0078167090146146,1.6539488897454098,-0.10773337464269757,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,2.6813851107199134,1.2787985183948616,-0.19093998781040267,1.1262641794309365,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.544166984823674,-0.08022423571315228,-0.21890038394992256,-0.7708818840672291,0.7613131382611684,-0.7708818840672291,1.037245922867657,-0.19093998781040267,-0.10773337464269757,0.2147447157493263,1.2572514626291789,0.8779778896871095,0.8779778896871095,0.4453447000259606,-0.44656700343867023,-0.6218757596842738,0.16216987090011553,-0.05282908073775324,-0.5045745330084603,-0.19093998781040267,1.1041400729155888,-0.41772541135227015,0.5691629585556126,0.18851682862821462,-0.5337396628232933,-0.710964802828651,2.177822330333986,0.18851682862821462,-0.30344983319990226,-1.884412751971023,0.2408529853896325,0.9922045075089839,0.9467966825508827,1.7143052013527764,-0.08022423571315228,-0.41772541135227015,-1.6521780628439882,0.5691629585556126,1.059631974750273,-2.189703350368514,0.642046718499613,-0.08022423571315228,-0.710964802828651,-0.6218757596842738,1.4900722702883373,0.544638339789795,-0.16309171563110678,0.13570438202306856,0.2408529853896325,1.014770461288004,1.6133853485657363,-1.2966959112582077,-0.2469724530743794,0.4453447000259606,1.8136359864985119,0.18851682862821462,0.3184545058121038,0.49523405136401416,1.3002667781715258
3,401
Purine nucleotide transport
8
13
2.843446
0.004463
O43808,P12235,P41440,O00400,Q8TB61,Q99808,P12236,Q08722
Processes and pathways
GO Biological process
msigdb_gobp
35,253,70,11,140,274,462,63
11,1607,35,537,253,462,70,63,1057,2404,140,2705,274
3.8544190981954287,0.028667653788611115,2.8360067907741575,0.7613131382611684,1.2572514626291789,0.8779778896871095,2.177822330333986,2.233550772463256,0.3440786823573308,-0.41772541135227015,1.6942507925226085,-0.6218757596842738,1.1921286759414857
3,401
Purine nucleotide transmembrane transporter activity
7
11
2.837698
0.004544
O43808,P12235,P41440,O00400,Q8TB61,Q99808,P12236
Functions
GO Molecular function
msigdb_gomf
35,253,70,11,140,274,462
11,1607,35,537,253,462,70,1057,2404,140,274
3.8544190981954287,0.028667653788611115,2.8360067907741575,0.7613131382611684,1.2572514626291789,0.8779778896871095,2.177822330333986,0.3440786823573308,-0.41772541135227015,1.6942507925226085,1.1921286759414857
3,401
Carbohydrate derivative transmembrane transporter activity
8
11
2.834153
0.004595
O43808,P12235,P41440,P05141,O00400,Q8TB61,Q99808,P12236
Functions
GO Molecular function
msigdb_gomf
35,253,70,537,11,140,274,462
552,11,35,537,253,462,70,1057,2404,140,274
0.7376735390494176,3.8544190981954287,2.8360067907741575,0.7613131382611684,1.2572514626291789,0.8779778896871095,2.177822330333986,0.3440786823573308,-0.41772541135227015,1.6942507925226085,1.1921286759414857
3,401
Malignant genitourinary tract tumor
15
22
2.827804
0.004687
P62847,P08708,P18077,Q969E8,P46777,P61313,P62854,P62244,Q07020,P61254,P60866,P61353,P62081,P52701,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,591,331,109,234,773,149,367,402,339,843,560,221
508,444,2992,221,1321,331,2111,560,842,402,367,109,339,843,773,297,234,1327,1376,1052,149,591
0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,0.18851682862821462,1.059631974750273,-0.2469724530743794,0.7376735390494176,0.49523405136401416,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.7139285396999346
3,401
Rab geranylgeranylation
14
21
2.804792
0.005035
P53611,P51148,O95716,P20340,P61026,Q13636,P61020,P61019,P61006,P61106,Q9NP72,P62820,P51149,Q9H0U4
Processes and pathways
Reactome Pathways
msigdb_reactome
128,911,1008,254,478,949,704,772,646,584,1026,804,1015,261
1008,1852,1665,1045,254,911,1015,1326,128,646,772,704,478,584,804,949,1729,2033,261,1026,1456
0.3695803896161305,-0.10773337464269757,0.001617352823824191,0.3440786823573308,1.2572514626291789,0.4453447000259606,0.3695803896161305,0.18851682862821462,1.7542239904369825,0.642046718499613,0.544638339789795,0.5935714761388575,0.8548449707097387,0.7139285396999346,0.5199959431965512,0.42021400684349175,-0.025548389325393668,-0.19093998781040267,1.2572514626291789,0.3695803896161305,0.13570438202306856
3,401
Intrinsic component of organelle membrane
41
136
2.801595
0.005085
P12235,O95563,O95470,O00767,P57088,Q8TB61,Q9H3K2,Q8N8Q8,Q9Y282,Q9Y2R0,Q9BUN8,O75880,Q12981,O43752,O15258,O43808,Q15041,Q9UBM7,Q5J8M3,Q9UM00,O43819,O15118,Q15629,Q8N4V1,Q5XKP0,Q9HC21,P57105,P61619,O60830,Q13505,P17152,O60499,Q6NTF9,P42892,Q15070,Q9BWH2,Q14739,Q6P4A7,O75844,Q9NQC3,Q6Y1H2
Localization
GO Cellular component
msigdb_gocc
253,506,505,138,139,140,13,143,415,24,27,28,156,397,396,35,37,39,309,315,419,417,52,54,450,74,466,467,458,480,219,92,98,355,104,497,106,514,122,126,515
1886,552,138,1606,417,396,1250,1073,397,35,419,92,458,2638,2749,122,28,2640,2504,1893,504,1117,505,506,1799,1846,1309,1708,767,253,3353,219,2687,1852,1045,3290,2512,3144,3056,355,3194,1124,2786,1015,583,139,466,704,467,3277,741,3350,1476,156,480,1725,106,3240,37,104,1816,52,2400,2076,2450,2078,2915,1784,309,953,450,98,514,987,515,888,2406,855,623,1337,2124,1434,54,2892,143,1060,785,1974,2665,140,686,589,2864,2409,754,1874,3047,894,2084,1229,2035,3346,2833,1181,1289,27,497,1066,13,1692,1745,74,718,3171,1002,126,2137,633,3081,2461,1984,1695,2365,39,1986,1300,3003,315,415,24,2424,2233,1357,2328,1149,1110
-0.135356023882502,0.7376735390494176,1.6942507925226085,0.028667653788611115,0.9239525336517246,0.9467966825508827,0.2147447157493263,0.3184545058121038,0.9467966825508827,2.8360067907741575,0.9239525336517246,2.0269216832537302,0.8779778896871095,-0.5923906667876935,-0.6811632058277461,1.7938933718647914,3.020731201810017,-0.5923906667876935,-0.5045745330084603,-0.135356023882502,0.8082816835493837,0.2927084466196836,0.8082816835493837,0.8082816835493837,-0.08022423571315228,-0.10773337464269757,0.18851682862821462,-0.025548389325393668,0.544638339789795,1.2572514626291789,-2.2240827955771967,1.3642073059600701,-0.6218757596842738,-0.10773337464269757,0.3440786823573308,-1.7180591941474048,-0.5045745330084603,-1.233329760418191,-1.0456168391676224,1.014770461288004,-1.3604554853890702,0.2927084466196836,-0.710964802828651,0.3695803896161305,0.7139285396999346,1.6942507925226085,0.8779778896871095,0.5935714761388575,0.8779778896871095,-1.6521780628439882,0.5691629585556126,-2.189703350368514,0.10912089420536077,1.6337001434401104,0.8548449707097387,-0.025548389325393668,1.8920056904356866,-1.4891452293299312,2.8189856921283467,1.9114506472351467,-0.08022423571315228,2.487824819755659,-0.41772541135227015,-0.21890038394992256,-0.44656700343867023,-0.21890038394992256,-0.8312150461506137,-0.05282908073775324,1.1041400729155888,0.42021400684349175,0.9010133357750852,1.9694400030270989,0.8082816835493837,0.3949590324162235,0.8082816835493837,0.4703509047116417,-0.41772541135227015,0.49523405136401416,0.6661166045339998,0.18851682862821462,-0.2469724530743794,0.13570438202306856,2.4699656883852037,-0.8009966357602808,1.6741322290310687,0.3440786823573308,0.544638339789795,-0.16309171563110678,-0.5923906667876935,1.6942507925226085,0.6178655297596958,0.7139285396999346,-0.7708818840672291,-0.41772541135227015,0.5691629585556126,-0.10773337464269757,-1.0146826095408896,0.4703509047116417,-0.21890038394992256,0.2408529853896325,-0.19093998781040267,-2.1554148991440814,-0.7408711516403494,0.2668410830881398,0.2147447157493263,3.037302888343568,0.8316133279582852,0.3440786823573308,3.6882822134218296,0.001617352823824191,-0.025548389325393668,2.1404139980394676,0.5935714761388575,-1.2966959112582077,0.3949590324162235,1.7740895644817878,-0.2469724530743794,0.6661166045339998,-1.0766519715520646,-0.44656700343867023,-0.16309171563110678,0.001617352823824191,-0.3889924804727667,2.8019254667161024,-0.16309171563110678,0.2147447157493263,-0.9224886791663648,1.1041400729155888,0.9467966825508827,3.2334307204873185,-0.41772541135227015,-0.30344983319990226,0.18851682862821462,-0.3603686262084453,0.2927084466196836,0.3184545058121038
3,401
Cholesterol biosynthesis
6
15
2.784526
0.005361
P04035,Q9UBM7,Q15392,Q13131,Q14739,Q16850
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
443,39,7,425,106,53
1308,443,1464,2008,465,2693,984,425,1523,106,7,1270,2573,53,39
0.18851682862821462,0.9010133357750852,0.10912089420536077,-0.19093998781040267,0.8779778896871095,-0.6218757596842738,0.3949590324162235,0.9239525336517246,0.08241993256639264,1.8920056904356866,4.133951074558761,0.2147447157493263,-0.5337396628232933,2.487824819755659,2.8019254667161024
3,401
Serine hydrolase activity
6
19
2.770195
0.005602
Q6NTF9,P42785,P67812,Q9HB40,Q9H3G5,O14773
Functions
GO Molecular function
msigdb_gomf
98,73,42,12,209,22
22,727,2907,673,1949,2754,73,1772,2607,2154,42,281,3223,810,1273,98,2214,209,12
3.4405094326495345,0.5691629585556126,-0.8312150461506137,0.6178655297596958,-0.16309171563110678,-0.6811632058277461,2.1404139980394676,-0.05282908073775324,-0.5630118383388776,-0.27515574959433703,2.7160278165306524,1.1702575091989806,-1.4246060531713614,0.5199959431965512,0.2147447157493263,1.9694400030270989,-0.30344983319990226,1.4064557073170705,3.703522774064278
3,401
Partial duplication of the phalanx of hand
15
22
2.745499
0.006042
Q8WVQ1,P08708,P62847,Q9BXW9,P18077,Q969E8,P46777,P61313,P62854,P62244,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
787,508,297,762,444,591,331,109,234,773,149,367,402,339,221
508,444,2992,221,331,2111,2441,402,367,109,339,843,773,297,234,1327,1376,1052,149,787,591,762
0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,-0.44656700343867023,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.544638339789795,0.7139285396999346,0.5691629585556126
3,401
Lymphocyte apoptotic process
6
17
2.734036
0.006256
Q07812,P62753,Q9HCL2,P00813,Q96EY1,P14174
Processes and pathways
GO Biological process
msigdb_gobp
289,110,111,18,283,29
2235,18,2964,2599,29,365,2010,1324,110,289,883,1484,283,1284,967,111,2185
-0.3318542687573309,3.53430786323273,-0.8919614192603897,-0.5630118383388776,2.9874793053049182,0.9922045075089839,-0.19093998781040267,0.18851682862821462,1.872502281604809,1.1483029978313013,0.4703509047116417,0.10912089420536077,1.1702575091989806,0.2147447157493263,0.42021400684349175,1.852939889172417,-0.27515574959433703
3,401
Nucleotide transmembrane transport
7
10
2.705173
0.006827
Q9BSK2,O43808,P12235,P41440,Q8TB61,P12236,Q9H2D1
Processes and pathways
GO Biological process
msigdb_gobp
32,35,253,70,140,462,484
1607,35,537,253,462,70,140,2705,32,484
0.028667653788611115,2.8360067907741575,0.7613131382611684,1.2572514626291789,0.8779778896871095,2.177822330333986,1.6942507925226085,-0.6218757596842738,2.9540811147426025,0.8548449707097387
3,401
Macrocytic anemia
15
37
2.693083
0.007079
P00374,P62847,P08708,P41440,P18077,P46777,P61313,P62854,Q07020,P61254,Q6P4A7,P60866,P61353,P62263,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,297,508,70,444,331,109,234,149,367,514,402,339,190,221
1248,2806,2747,2640,2,1658,508,2150,1662,444,1947,2992,70,221,331,2111,402,1718,367,109,339,843,773,190,297,234,1327,1376,1052,149,2026,514,1433,591,1287,1401,1653
0.2147447157493263,-0.7408711516403494,-0.6811632058277461,-0.5923906667876935,5.0422806067498716,0.001617352823824191,0.8082816835493837,-0.27515574959433703,0.001617352823824191,0.9010133357750852,-0.16309171563110678,-0.9224886791663648,2.177822330333986,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,-0.025548389325393668,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.4692762530118126,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,-0.19093998781040267,0.8082816835493837,0.13570438202306856,0.7139285396999346,0.2147447157493263,0.16216987090011553,0.028667653788611115
3,401
Osteosarcoma
12
26
2.685793
0.007236
Q13126,P62847,P08708,P18077,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,297,508,444,331,109,234,149,367,402,339,221
1461,2430,2964,508,444,2992,221,1085,331,2111,402,367,109,339,843,773,297,234,1327,1376,1052,149,0,1863,591,2628
0.10912089420536077,-0.44656700343867023,-0.8919614192603897,0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,0.3184545058121038,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,6.004280351550185,-0.10773337464269757,0.7139285396999346,-0.5630118383388776
3,401
Mitochondrial nucleotide transporter subfamily
7
10
2.672146
0.007537
Q9BSK2,O43808,P12235,Q70HW3,Q9HC21,P12236,Q9H2D1
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
32,35,253,102,74,462,484
35,537,253,462,1057,2404,102,32,484,74
2.8360067907741575,0.7613131382611684,1.2572514626291789,0.8779778896871095,0.3440786823573308,-0.41772541135227015,1.9501672914836015,2.9540811147426025,0.8548449707097387,2.1404139980394676
3,401
Pore complex
6
9
2.663278
0.007738
Q07812,P12235,Q9Y277,P45880,P30405,P21796
Localization
GO Cellular component
msigdb_gocc
289,253,72,295,488,240
1799,537,253,240,488,295,1904,289,72
-0.08022423571315228,0.7613131382611684,1.2572514626291789,1.3002667781715258,0.8316133279582852,1.1262641794309365,-0.135356023882502,1.1483029978313013,2.1591440513142732
3,401
Oxidoreduction driven active transmembrane transporter activity
11
31
2.655575
0.007917
O75306,P00403,P03886,O75380,O95139,Q9Y6M9,Q16795,O43676,P51970,O95168,O43674
Functions
GO Molecular function
msigdb_gomf
226,162,3,292,44,246,183,145,366,248,94
2498,666,1198,94,145,974,226,292,2472,1705,44,248,1999,838,1081,162,3,1850,1256,463,2434,1368,2380,733,1325,366,2698,183,783,929,246
-0.5045745330084603,0.6178655297596958,0.2408529853896325,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.544166984823674,-0.10773337464269757,0.2147447157493263,0.8779778896871095,-0.44656700343867023,0.16216987090011553,-0.41772541135227015,0.5691629585556126,0.18851682862821462,0.9922045075089839,-0.6218757596842738,1.4900722702883373,0.544638339789795,0.4453447000259606,1.3002667781715258
3,401
Rough endoplasmic reticulum
18
39
2.655366
0.007922
O60568,P62266,Q15041,Q9Y5M8,P05067,Q5VV42,P60059,Q9UQB8,P61353,Q5BJF2,Q07020,P61619,P62854,Q02878,P36578,P61106,Q8TCT9,Q07065
Localization
GO Cellular component
msigdb_gocc
225,165,37,301,263,198,561,80,339,48,149,467,234,119,148,584,686,158
2426,225,2104,2286,1800,263,1712,1947,2512,1950,148,2653,2153,561,878,584,339,467,165,234,1327,678,2567,119,149,158,37,48,198,2793,686,1874,1229,2134,823,1299,2325,80,301
-0.44656700343867023,1.3429703349028668,-0.2469724530743794,-0.3603686262084453,-0.08022423571315228,1.2356247347543958,-0.025548389325393668,-0.16309171563110678,-0.5045745330084603,-0.16309171563110678,1.6539488897454098,-0.5923906667876935,-0.27515574959433703,0.7376735390494176,0.4703509047116417,0.7139285396999346,1.037245922867657,0.8779778896871095,1.5930038530109396,1.32165710213149,0.18851682862821462,0.6178655297596958,-0.5337396628232933,1.8136359864985119,1.6539488897454098,1.6133853485657363,2.8189856921283467,2.576453896227463,1.4274687241394302,-0.710964802828651,0.6178655297596958,-0.10773337464269757,0.2408529853896325,-0.2469724530743794,0.5199959431965512,0.2147447157493263,-0.3603686262084453,2.1216317365456785,1.1262641794309365
3,401
Small ribosomal subunit
30
47
2.645171
0.008165
Q7Z478,P08708,P62277,P62244,P62841,P60866,P82912,P46781,P62266,P62847,P63220,P82675,P46782,P61247,Q9Y2R5,P62263,P62280,Q9Y2R9,P62241,O15235,Q9Y399,P62269,P15880,P82930,P62081,P82933,P62854,P62753,P62701,P82914
Localization
GO Cellular component
msigdb_gocc
657,508,265,773,529,402,280,279,165,297,678,424,801,306,328,190,447,599,195,692,350,705,215,340,843,235,234,110,233,249
692,2148,508,2149,215,1317,2108,2992,279,801,2111,944,402,306,843,195,773,1569,190,165,705,265,447,233,110,529,297,844,234,1327,678,1263,2972,2993,424,280,249,340,235,657,1528,1290,1031,328,599,350,1107
0.5935714761388575,-0.27515574959433703,0.8082816835493837,-0.27515574959433703,1.385368830001817,0.18851682862821462,-0.2469724530743794,-0.9224886791663648,1.1702575091989806,0.5199959431965512,-0.2469724530743794,0.42021400684349175,0.9467966825508827,1.1041400729155888,0.49523405136401416,1.4484086529903741,0.544638339789795,0.05560201529260138,1.4692762530118126,1.5930038530109396,0.5935714761388575,1.2356247347543958,0.9010133357750852,1.32165710213149,1.872502281604809,0.7848487317778781,1.1262641794309365,0.49523405136401416,1.32165710213149,0.18851682862821462,0.6178655297596958,0.2147447157493263,-0.8919614192603897,-0.9224886791663648,0.9239525336517246,1.1702575091989806,1.2787985183948616,1.037245922867657,1.32165710213149,0.642046718499613,0.08241993256639264,0.2147447157493263,0.3695803896161305,1.0819296780167726,0.7139285396999346,1.037245922867657,0.3184545058121038
3,401
Abnormal number of erythroid precursors
13
25
2.642929
0.008219
P62847,P08708,P18077,Q9Y606,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P62263,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,269,331,109,234,149,367,402,339,190,221
1203,2642,2964,1659,508,444,2992,221,331,2111,402,367,109,339,843,773,190,297,234,1327,1376,1052,149,591,269
0.2408529853896325,-0.5923906667876935,-0.8919614192603897,0.001617352823824191,0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.4692762530118126,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.7139285396999346,1.2139174422855383
3,401
Amino acid transport
6
20
2.624863
0.008668
Q9H936,Q15041,O60831,P30825,Q9Y619,P21359
Processes and pathways
GO Biological process
msigdb_gobp
359,37,202,88,26,287
2332,202,872,837,2242,2003,287,88,1809,37,1524,2790,514,2705,894,1233,359,1692,1697,26
-0.3889924804727667,1.4064557073170705,0.4703509047116417,0.49523405136401416,-0.3318542687573309,-0.19093998781040267,1.1483029978313013,2.0459717130687864,-0.08022423571315228,2.8189856921283467,0.08241993256639264,-0.710964802828651,0.8082816835493837,-0.6218757596842738,0.4703509047116417,0.2408529853896325,1.014770461288004,0.001617352823824191,0.001617352823824191,3.053838714425047
3,401
Synthesis of dna
19
92
2.621871
0.008745
P28070,P49005,P35244,Q9Y619,Q9Y248,P49720,P28074,P28072,P49721,Q14181,P41440,P20248,O43242,Q9NR33,P24941,O43913,Q14691,P20618,O75832
Processes and pathways
Reactome Pathways
msigdb_reactome
255,399,147,26,300,296,59,194,67,321,70,445,329,79,464,213,342,103,487
1504,2046,1034,1604,2237,329,213,3101,487,2376,2684,906,2753,1084,445,103,464,2007,620,1666,977,909,1948,1416,255,194,59,1257,1467,2342,1620,1953,147,2722,1469,643,1954,980,1669,2650,70,2110,1622,399,1163,1216,296,67,2061,1259,1672,1810,1474,803,2011,1720,1959,1375,1017,2305,606,2017,1572,510,1477,1479,321,2483,342,1018,3344,2922,3137,790,1494,1288,2624,2628,79,2136,721,1696,1698,2142,2043,3367,1301,1987,1457,300,2183,26
0.08241993256639264,-0.21890038394992256,0.3440786823573308,0.028667653788611115,-0.3318542687573309,1.059631974750273,1.385368830001817,-1.139023630624162,0.8316133279582852,-0.41772541135227015,-0.6218757596842738,0.4453447000259606,-0.6811632058277461,0.3184545058121038,0.9010133357750852,1.930837675632946,0.8779778896871095,-0.19093998781040267,0.6661166045339998,0.001617352823824191,0.3949590324162235,0.4453447000259606,-0.16309171563110678,0.13570438202306856,1.2572514626291789,1.4484086529903741,2.270451887980421,0.2147447157493263,0.10912089420536077,-0.3889924804727667,0.028667653788611115,-0.16309171563110678,1.6539488897454098,-0.6514667327479815,0.10912089420536077,0.642046718499613,-0.16309171563110678,0.3949590324162235,0.001617352823824191,-0.5923906667876935,2.177822330333986,-0.2469724530743794,0.028667653788611115,0.9467966825508827,0.2668410830881398,0.2408529853896325,1.1262641794309365,2.1964492630808774,-0.21890038394992256,0.2147447157493263,0.001617352823824191,-0.08022423571315228,0.10912089420536077,0.5199959431965512,-0.19093998781040267,-0.025548389325393668,-0.16309171563110678,0.16216987090011553,0.3695803896161305,-0.3603686262084453,0.6900767143139638,-0.19093998781040267,0.05560201529260138,0.8082816835493837,0.10912089420536077,0.10912089420536077,1.0819296780167726,-0.4755168460231504,1.037245922867657,0.3695803896161305,-2.1554148991440814,-0.8312150461506137,-1.201794990466699,0.544638339789795,0.10912089420536077,0.2147447157493263,-0.5630118383388776,-0.5630118383388776,2.1216317365456785,-0.2469724530743794,0.5935714761388575,0.001617352823824191,0.001617352823824191,-0.2469724530743794,-0.19093998781040267,-2.4672666629853417,0.2147447157493263,-0.16309171563110678,0.13570438202306856,1.1262641794309365,-0.27515574959433703,3.053838714425047
3,401
Transporter activity
56
185
2.620529
0.008779
P03886,P00846,P53985,P12235,O00400,Q8TB61,Q99808,Q8IXU6,O43676,Q9Y619,P53007,Q96AA3,P0CG08,Q9BSK2,Q9H2V7,Q9HD20,O43808,P00403,Q07812,P45880,O95202,O95139,O75964,O75380,O43772,Q9UM00,P30536,Q9NVV0,O15118,Q16795,Q8N4V1,P28288,P56134,P41440,P24539,Q9Y277,Q9HC21,Q02978,P61619,P13073,P12236,O15173,Q9C0H2,P30825,O60830,P08183,O43674,O75306,Q9H936,Q70HW3,Q9Y6M9,Q9Y584,P21796,Q9UBX3,P51970,O95168
Functions
GO Molecular function
msigdb_gomf
3,4,133,253,11,140,274,21,145,26,400,159,278,32,33,160,35,162,289,295,293,44,168,292,47,315,294,312,417,183,54,302,446,70,71,72,74,332,467,463,462,86,347,88,458,338,94,226,359,102,246,245,240,121,366,248
552,2498,2187,11,666,1198,2332,1606,417,86,1607,94,145,1995,47,35,458,1843,974,226,292,2472,1705,872,2808,168,2504,44,248,1999,293,838,506,1081,1799,162,4,3,873,1801,2052,2848,537,2849,3025,3371,3192,338,2003,1850,278,1256,253,462,463,908,3142,3143,2434,2687,1368,1766,2510,240,1803,2006,71,3055,302,2380,294,88,733,1319,1621,2562,942,2784,70,295,2383,1049,737,1325,2198,3320,1217,366,1623,2607,400,133,1809,446,2255,561,2389,467,3363,3277,2610,741,1053,332,3350,289,650,1329,3181,1172,655,1816,2790,2698,183,2355,1057,2404,1866,514,1731,2452,102,783,1336,21,54,1176,2031,1974,140,2705,1343,626,1345,159,3047,2494,894,1643,2709,3226,2035,1588,274,1740,32,595,1929,1445,3321,3376,347,1878,2273,484,1233,33,2802,359,1692,74,160,3171,2137,2226,1834,312,3271,929,121,2325,1356,1697,315,2092,72,1195,245,832,1109,26,1111,866,246
0.7376735390494176,-0.5045745330084603,-0.30344983319990226,3.8544190981954287,0.6178655297596958,0.2408529853896325,-0.3889924804727667,0.028667653788611115,0.9239525336517246,2.0459717130687864,0.028667653788611115,2.0078167090146146,1.6539488897454098,-0.19093998781040267,2.629109857257126,2.8360067907741575,0.8779778896871095,-0.10773337464269757,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,0.4703509047116417,-0.7408711516403494,1.5725549938573544,-0.5045745330084603,2.6813851107199134,1.2787985183948616,-0.19093998781040267,1.1262641794309365,0.49523405136401416,0.8082816835493837,0.3184545058121038,-0.08022423571315228,1.5930038530109396,4.4328621068997585,4.544166984823674,0.4703509047116417,-0.08022423571315228,-0.21890038394992256,-0.7708818840672291,0.7613131382611684,-0.7708818840672291,-0.9838496152113808,-2.608194452751914,-1.3604554853890702,1.037245922867657,-0.19093998781040267,-0.10773337464269757,1.1702575091989806,0.2147447157493263,1.2572514626291789,0.8779778896871095,0.8779778896871095,0.4453447000259606,-1.233329760418191,-1.233329760418191,-0.44656700343867023,-0.6218757596842738,0.16216987090011553,-0.05282908073775324,-0.5045745330084603,1.3002667781715258,-0.08022423571315228,-0.19093998781040267,2.1591440513142732,-1.0456168391676224,1.1041400729155888,-0.41772541135227015,1.1262641794309365,2.0459717130687864,0.5691629585556126,0.18851682862821462,0.028667653788611115,-0.5337396628232933,0.42021400684349175,-0.710964802828651,2.177822330333986,1.1262641794309365,-0.41772541135227015,0.3440786823573308,0.5691629585556126,0.18851682862821462,-0.30344983319990226,-1.884412751971023,0.2408529853896325,0.9922045075089839,0.028667653788611115,-0.5630118383388776,0.9467966825508827,1.7143052013527764,-0.08022423571315228,0.9010133357750852,-0.3318542687573309,0.7376735390494176,-0.41772541135227015,0.8779778896871095,-2.397336531738707,-1.6521780628439882,-0.5630118383388776,0.5691629585556126,0.3440786823573308,1.059631974750273,-2.189703350368514,1.1483029978313013,0.642046718499613,0.18851682862821462,-1.328526673320553,0.2668410830881398,0.642046718499613,-0.08022423571315228,-0.710964802828651,-0.6218757596842738,1.4900722702883373,-0.3889924804727667,0.3440786823573308,-0.41772541135227015,-0.10773337464269757,0.8082816835493837,-0.025548389325393668,-0.44656700343867023,1.9501672914836015,0.544638339789795,0.18851682862821462,3.45621827618043,2.4699656883852037,0.2668410830881398,-0.19093998781040267,-0.16309171563110678,1.6942507925226085,-0.6218757596842738,0.18851682862821462,0.6661166045339998,0.18851682862821462,1.6133853485657363,-1.0146826095408896,-0.4755168460231504,0.4703509047116417,0.028667653788611115,-0.6218757596842738,-1.4246060531713614,-0.19093998781040267,0.05560201529260138,1.1921286759414857,-0.025548389325393668,2.9540811147426025,0.7139285396999346,-0.135356023882502,0.13570438202306856,-1.884412751971023,-2.6791885162262963,1.037245922867657,-0.10773337464269757,-0.3318542687573309,0.8548449707097387,0.2408529853896325,2.886837996870774,-0.710964802828651,1.014770461288004,0.001617352823824191,2.1404139980394676,1.6133853485657363,-1.2966959112582077,-0.2469724530743794,-0.30344983319990226,-0.08022423571315228,1.1041400729155888,-1.6193800795521127,0.4453447000259606,1.8136359864985119,-0.3603686262084453,0.18851682862821462,0.001617352823824191,1.1041400729155888,-0.21890038394992256,2.1591440513142732,0.2668410830881398,1.3002667781715258,0.5199959431965512,0.3184545058121038,3.053838714425047,0.3184545058121038,0.49523405136401416,1.3002667781715258
3,401
Dicarboxylic acid transport
7
16
2.617516
0.008857
Q9H936,Q15041,P41440,O60831,Q02978,Q9UBX3,P21359
Processes and pathways
GO Biological process
msigdb_gobp
359,37,70,202,332,121,287
202,872,837,2242,287,70,1809,332,37,1524,2790,2705,484,359,121,1697
1.4064557073170705,0.4703509047116417,0.49523405136401416,-0.3318542687573309,1.1483029978313013,2.177822330333986,-0.08022423571315228,1.059631974750273,2.8189856921283467,0.08241993256639264,-0.710964802828651,-0.6218757596842738,0.8548449707097387,1.014770461288004,1.8136359864985119,0.001617352823824191
3,401
Cation transmembrane transporter activity
21
75
2.605095
0.009185
P00846,P12235,O00400,Q99808,Q9Y619,Q9HD20,P00403,O43808,O95202,O75964,Q9UM00,O43772,Q9NVV0,Q8N4V1,P56134,P24539,Q9HC21,P61619,P30825,Q9H936,Q70HW3
Functions
GO Molecular function
msigdb_gomf
4,253,11,274,26,160,162,35,293,168,315,47,312,54,446,71,74,467,88,359,102
11,1198,47,35,2808,168,293,162,4,2052,2848,537,2849,3025,3192,2003,1850,1256,253,463,908,3143,2687,1368,1766,2510,2006,71,3055,88,733,1319,1621,2562,2784,2383,2198,1809,446,2255,2389,467,3277,741,1053,1329,655,2790,2355,1731,2452,102,783,54,1974,626,1345,3047,894,274,1445,1878,1233,359,1692,74,160,312,3271,1356,315,1195,1109,26,866
3.8544190981954287,0.2408529853896325,2.629109857257126,2.8360067907741575,-0.7408711516403494,1.5725549938573544,1.1262641794309365,1.5930038530109396,4.4328621068997585,-0.21890038394992256,-0.7708818840672291,0.7613131382611684,-0.7708818840672291,-0.9838496152113808,-1.3604554853890702,-0.19093998781040267,-0.10773337464269757,0.2147447157493263,1.2572514626291789,0.8779778896871095,0.4453447000259606,-1.233329760418191,-0.6218757596842738,0.16216987090011553,-0.05282908073775324,-0.5045745330084603,-0.19093998781040267,2.1591440513142732,-1.0456168391676224,2.0459717130687864,0.5691629585556126,0.18851682862821462,0.028667653788611115,-0.5337396628232933,-0.710964802828651,-0.41772541135227015,-0.30344983319990226,-0.08022423571315228,0.9010133357750852,-0.3318542687573309,-0.41772541135227015,0.8779778896871095,-1.6521780628439882,0.5691629585556126,0.3440786823573308,0.18851682862821462,0.642046718499613,-0.710964802828651,-0.3889924804727667,-0.025548389325393668,-0.44656700343867023,1.9501672914836015,0.544638339789795,2.4699656883852037,-0.16309171563110678,0.6661166045339998,0.18851682862821462,-1.0146826095408896,0.4703509047116417,1.1921286759414857,0.13570438202306856,-0.10773337464269757,0.2408529853896325,1.014770461288004,0.001617352823824191,2.1404139980394676,1.6133853485657363,1.1041400729155888,-1.6193800795521127,0.18851682862821462,1.1041400729155888,0.2668410830881398,0.3184545058121038,3.053838714425047,0.49523405136401416
3,401
Nucleophile aminohydrolases, N-terminal [IPR029055]
12
18
2.601596
0.009279
P28070,P28072,P49721,Q99436,P20618,P49720,P08243,P60900,P25786,Q06210,P28074,P25789
Sequence
InterPro Superfamily
interpro_homologous_superfamily
255,194,67,790,103,296,672,803,620,776,59,909
2237,672,103,620,1666,977,909,1416,255,194,59,296,67,803,1423,776,790,2464
-0.3318542687573309,0.6178655297596958,1.930837675632946,0.6661166045339998,0.001617352823824191,0.3949590324162235,0.4453447000259606,0.13570438202306856,1.2572514626291789,1.4484086529903741,2.270451887980421,1.1262641794309365,2.1964492630808774,0.5199959431965512,0.13570438202306856,0.544638339789795,0.544638339789795,-0.44656700343867023
3,401
Migraine
7
25
2.594921
0.009461
P00403,P03886,Q4G176,P12235,P05067,Q9NQZ5,P21359
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
162,3,132,253,263,115,287
900,1248,2466,2747,1846,162,2051,1309,3,263,253,287,1321,1324,560,945,402,984,1265,2025,132,1227,895,115,1836
0.4453447000259606,0.2147447157493263,-0.4755168460231504,-0.6811632058277461,-0.10773337464269757,1.5930038530109396,-0.21890038394992256,0.18851682862821462,4.544166984823674,1.2356247347543958,1.2572514626291789,1.1483029978313013,0.18851682862821462,0.18851682862821462,0.7376735390494176,0.42021400684349175,0.9467966825508827,0.3949590324162235,0.2147447157493263,-0.19093998781040267,1.7342960667860914,0.2408529853896325,0.4703509047116417,1.8333179734584413,-0.08022423571315228
3,401
Diamond-Blackfan anemia
10
17
2.58413
0.009762
P62847,P08708,P18077,P46777,P62854,P61313,Q07020,P61254,P61353,P42766
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
297,508,444,331,234,109,149,367,339,221
508,444,2992,221,331,2111,367,109,339,843,773,297,234,1327,1052,149,591
0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.3440786823573308,1.6539488897454098,0.7139285396999346
3,401
Lipid biosynthesis
25
62
2.580013
0.00988
Q96G23,Q15392,Q9UKR5,Q9HBU6,O00767,Q6Y1H2,P35790,O15121,Q16739,Q9UBM7,Q13131,Q16850,Q92604,O75845,Q96BW9,P04035,P54646,O95864,O95674,Q9UHQ9,Q96N66,Q14739,Q9HCL2,P48449,O14735
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
6,7,137,136,138,515,14,526,290,39,425,53,453,316,592,443,465,337,336,362,237,106,111,125,127
1197,2776,138,127,526,316,336,337,1308,443,1313,1464,2853,14,2008,3073,125,1122,1324,841,877,465,2693,984,680,425,1523,106,743,7,1270,2573,290,53,1092,780,3378,515,989,2267,1582,589,453,592,6,237,1589,3019,2769,3170,1184,1649,136,111,2459,927,2461,1984,39,1986,362,137
0.2408529853896325,-0.710964802828651,1.6942507925226085,1.7542239904369825,0.7848487317778781,1.0819296780167726,1.037245922867657,1.037245922867657,0.18851682862821462,0.9010133357750852,0.18851682862821462,0.10912089420536077,-0.7708818840672291,3.642391628326361,-0.19093998781040267,-1.0766519715520646,1.7740895644817878,0.2927084466196836,0.18851682862821462,0.49523405136401416,0.4703509047116417,0.8779778896871095,-0.6218757596842738,0.3949590324162235,0.6178655297596958,0.9239525336517246,0.08241993256639264,1.8920056904356866,0.5691629585556126,4.133951074558761,0.2147447157493263,-0.5337396628232933,1.1483029978313013,2.487824819755659,0.3184545058121038,0.544638339789795,-2.7863373702683543,0.8082816835493837,0.3949590324162235,-0.3318542687573309,0.05560201529260138,0.7139285396999346,0.9010133357750852,0.7139285396999346,4.234710223736134,1.32165710213149,0.05560201529260138,-0.9531181920204688,-0.6811632058277461,-1.2966959112582077,0.2668410830881398,0.028667653788611115,1.7143052013527764,1.852939889172417,-0.44656700343867023,0.4453447000259606,-0.44656700343867023,-0.16309171563110678,2.8019254667161024,-0.16309171563110678,1.014770461288004,1.7143052013527764
3,401
Cytoprotection by hmox1
32
69
2.572999
0.010082
Q15008,P28070,Q13309,Q99436,P63208,P19784,Q8N8Q8,P67870,P30519,P15954,P68400,Q8TCT9,O75880,P25789,P00403,O00483,P49720,O43819,P60900,P28074,P28072,P49721,O43242,P13073,P25788,Q15648,P20618,Q13618,O75832,P25786,Q14145,Q86X55
Processes and pathways
Reactome Pathways
msigdb_reactome
1018,255,510,790,1017,270,143,648,23,907,774,686,28,909,162,666,296,419,803,59,194,67,329,463,977,357,103,884,487,620,622,1021
1504,2046,1034,666,1604,1198,2237,329,419,1609,487,28,162,1462,1851,1256,463,907,2753,270,103,1368,620,1666,977,909,1416,255,194,59,23,1954,2756,1807,2110,1622,296,67,1672,1419,1810,803,2011,1720,1959,1375,1017,648,774,2305,1572,510,1479,884,622,1018,357,1021,143,686,2922,2584,2866,790,1494,1442,1742,1301,1457
0.08241993256639264,-0.21890038394992256,0.3440786823573308,0.6178655297596958,0.028667653788611115,0.2408529853896325,-0.3318542687573309,1.059631974750273,0.9239525336517246,0.028667653788611115,0.8316133279582852,3.020731201810017,1.5930038530109396,0.10912089420536077,-0.10773337464269757,0.2147447157493263,0.8779778896871095,0.4453447000259606,-0.6811632058277461,1.1921286759414857,1.930837675632946,0.16216987090011553,0.6661166045339998,0.001617352823824191,0.3949590324162235,0.4453447000259606,0.13570438202306856,1.2572514626291789,1.4484086529903741,2.270451887980421,3.4405094326495345,-0.16309171563110678,-0.6811632058277461,-0.08022423571315228,-0.2469724530743794,0.028667653788611115,1.1262641794309365,2.1964492630808774,0.001617352823824191,0.13570438202306856,-0.08022423571315228,0.5199959431965512,-0.19093998781040267,-0.025548389325393668,-0.16309171563110678,0.16216987090011553,0.3695803896161305,0.642046718499613,0.544638339789795,-0.3603686262084453,0.05560201529260138,0.8082816835493837,0.10912089420536077,0.4703509047116417,0.6661166045339998,0.3695803896161305,1.014770461288004,0.3695803896161305,1.6741322290310687,0.6178655297596958,-0.8312150461506137,-0.5337396628232933,-0.7708818840672291,0.544638339789795,0.10912089420536077,0.13570438202306856,-0.025548389325393668,0.2147447157493263,0.13570438202306856
3,401
Increased serum lactate
34
107
2.558869
0.010501
Q7KZN9,P03886,P00846,P22695,P12235,Q9Y606,O75880,P35610,P00403,Q9BU61,Q8N5M1,O00483,Q9NVS9,O95831,O43819,Q16795,Q9H9J2,Q5XKP0,Q9NWS8,P13073,P82930,Q969Y2,O75306,Q9BW92,Q6P4A7,Q70HW3,P06737,Q9Y6M9,Q9Y584,Q5U5X0,Q9UBX3,P51970,Q00325,Q8NI60
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
783,3,4,509,253,269,28,157,162,822,814,666,572,46,419,183,717,450,597,463,340,755,226,761,514,102,601,246,245,491,121,366,741,517
2498,1248,666,419,974,226,1892,1705,3051,28,838,46,1158,162,2337,4,3,601,1661,1850,1042,2507,1313,253,463,3238,2434,1368,1119,509,2810,2380,2648,1258,157,1858,2754,2692,1807,1046,1900,1325,3011,366,3042,1126,1166,2654,2972,2993,340,741,882,1677,1266,1680,183,1093,2078,1094,1273,2526,1682,1635,491,450,1971,514,1867,102,783,1387,2998,2407,814,2454,517,2949,755,993,2271,895,1738,1588,1442,822,1289,761,2323,2586,1981,1294,717,1450,572,597,2675,929,121,830,1031,1032,1107,245,269,1755,246
-0.5045745330084603,0.2147447157493263,0.6178655297596958,0.9239525336517246,0.3949590324162235,1.3429703349028668,-0.135356023882502,-0.025548389325393668,-1.0456168391676224,3.020731201810017,0.49523405136401416,2.664001817387791,0.2668410830881398,1.5930038530109396,-0.3889924804727667,4.4328621068997585,4.544166984823674,0.6900767143139638,0.001617352823824191,-0.10773337464269757,0.3440786823573308,-0.5045745330084603,0.18851682862821462,1.2572514626291789,0.8779778896871095,-1.4891452293299312,-0.44656700343867023,0.16216987090011553,0.2927084466196836,0.8082816835493837,-0.7408711516403494,-0.41772541135227015,-0.5923906667876935,0.2147447157493263,1.6133853485657363,-0.10773337464269757,-0.6811632058277461,-0.6218757596842738,-0.08022423571315228,0.3440786823573308,-0.135356023882502,0.18851682862821462,-0.9531181920204688,0.9922045075089839,-1.0146826095408896,0.2927084466196836,0.2668410830881398,-0.5923906667876935,-0.8919614192603897,-0.9224886791663648,1.037245922867657,0.5691629585556126,0.4703509047116417,0.001617352823824191,0.2147447157493263,0.001617352823824191,1.4900722702883373,0.3184545058121038,-0.21890038394992256,0.3184545058121038,0.2147447157493263,-0.5045745330084603,0.001617352823824191,0.028667653788611115,0.8316133279582852,0.9010133357750852,-0.16309171563110678,0.8082816835493837,-0.10773337464269757,1.9501672914836015,0.544638339789795,0.16216987090011553,-0.9224886791663648,-0.41772541135227015,0.5199959431965512,-0.44656700343867023,0.8082816835493837,-0.8615367583845711,0.5691629585556126,0.3949590324162235,-0.3318542687573309,0.4703509047116417,-0.025548389325393668,0.05560201529260138,0.13570438202306856,0.5199959431965512,0.2147447157493263,0.5691629585556126,-0.3603686262084453,-0.5337396628232933,-0.16309171563110678,0.2147447157493263,0.5935714761388575,0.13570438202306856,0.7376735390494176,0.7139285396999346,-0.5923906667876935,0.4453447000259606,1.8136359864985119,0.5199959431965512,0.3695803896161305,0.3695803896161305,0.3184545058121038,1.3002667781715258,1.2139174422855383,-0.025548389325393668,1.3002667781715258
3,401
Atp metabolic process
26
115
2.550398
0.01076
P03886,P00846,P05067,Q9H3K2,O43676,Q9BSK2,P00403,P14406,Q13131,O95139,O75964,O75380,P30536,Q16795,P61586,Q9BRR6,P56134,P24539,P13073,P54646,O43674,O75306,Q9Y6M9,P30405,P51970,O95168
Processes and pathways
GO Biological process
msigdb_gobp
3,4,263,13,145,32,162,163,425,44,168,292,294,183,423,454,446,71,463,465,94,226,246,488,366,248
2498,1248,666,1198,1758,94,145,974,226,975,1609,292,2472,1705,872,2808,168,2641,44,248,1999,838,1081,1158,162,2051,2879,4,3,2001,1707,2964,2848,263,671,2849,2505,1612,1614,1850,2244,2507,1895,2965,3178,1256,2683,463,163,1712,619,3238,907,768,1946,3143,1465,2434,1368,1766,2245,509,71,3055,1804,2380,488,294,1258,733,1562,1014,1621,2689,2784,2756,1321,2383,1325,2112,366,1372,877,465,2757,2942,446,2255,3089,2442,423,1475,2071,1677,425,2698,183,1057,956,783,1137,2413,454,32,1981,13,1187,3126,1027,2956,1697,3050,1881,2233,246
-0.5045745330084603,0.2147447157493263,0.6178655297596958,0.2408529853896325,-0.05282908073775324,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,0.3949590324162235,0.028667653788611115,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,0.4703509047116417,-0.7408711516403494,1.5725549938573544,-0.5923906667876935,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,0.2668410830881398,1.5930038530109396,-0.21890038394992256,-0.8009966357602808,4.4328621068997585,4.544166984823674,-0.19093998781040267,-0.025548389325393668,-0.8919614192603897,-0.7708818840672291,1.2356247347543958,0.6178655297596958,-0.7708818840672291,-0.5045745330084603,0.028667653788611115,0.028667653788611115,-0.10773337464269757,-0.3318542687573309,-0.5045745330084603,-0.135356023882502,-0.8919614192603897,-1.328526673320553,0.2147447157493263,-0.6218757596842738,0.8779778896871095,1.5930038530109396,-0.025548389325393668,0.6661166045339998,-1.4891452293299312,0.4453447000259606,0.544638339789795,-0.16309171563110678,-1.233329760418191,0.10912089420536077,-0.44656700343867023,0.16216987090011553,-0.05282908073775324,-0.3318542687573309,0.8082816835493837,2.1591440513142732,-1.0456168391676224,-0.08022423571315228,-0.41772541135227015,0.8316133279582852,1.1262641794309365,0.2147447157493263,0.5691629585556126,0.05560201529260138,0.3695803896161305,0.028667653788611115,-0.6218757596842738,-0.710964802828651,-0.6811632058277461,0.18851682862821462,-0.41772541135227015,0.18851682862821462,-0.2469724530743794,0.9922045075089839,0.16216987090011553,0.4703509047116417,0.8779778896871095,-0.6811632058277461,-0.8615367583845711,0.9010133357750852,-0.3318542687573309,-1.1077876774028323,-0.44656700343867023,0.9239525336517246,0.10912089420536077,-0.21890038394992256,0.001617352823824191,0.9239525336517246,-0.6218757596842738,1.4900722702883373,0.3440786823573308,0.42021400684349175,0.544638339789795,0.2927084466196836,-0.41772541135227015,0.9010133357750852,2.9540811147426025,-0.16309171563110678,3.6882822134218296,0.2668410830881398,-1.1703595082645744,0.3695803896161305,-0.8615367583845711,0.001617352823824191,-1.0146826095408896,-0.10773337464269757,-0.30344983319990226,1.3002667781715258
3,401
Cellular response to chemical stress
22
78
2.550008
0.010772
P28070,Q13309,P19784,Q8N8Q8,P67870,P30519,P00390,Q8TCT9,O75880,P00403,P49720,O43819,P28074,P28072,P49721,O43242,P13073,Q15648,P20618,O75832,P25786,Q14145
Processes and pathways
Reactome Pathways
msigdb_reactome
255,510,270,143,648,23,146,686,28,162,296,419,59,194,67,329,463,357,103,487,620,622
1504,2046,1034,666,1604,1198,2237,329,419,1609,487,28,146,162,2241,3084,1462,1851,1256,463,907,2753,270,103,1368,620,1666,977,909,1416,255,194,59,1318,1370,1619,23,2291,1954,2756,1807,2110,1622,296,67,1672,1419,1810,803,2011,1720,1959,1375,1017,648,774,2305,1572,510,1479,884,622,1018,357,2619,1021,143,686,2922,2893,2584,2866,790,1494,1442,1742,1301,1457
0.08241993256639264,-0.21890038394992256,0.3440786823573308,0.6178655297596958,0.028667653788611115,0.2408529853896325,-0.3318542687573309,1.059631974750273,0.9239525336517246,0.028667653788611115,0.8316133279582852,3.020731201810017,1.6539488897454098,1.5930038530109396,-0.3318542687573309,-1.1077876774028323,0.10912089420536077,-0.10773337464269757,0.2147447157493263,0.8779778896871095,0.4453447000259606,-0.6811632058277461,1.1921286759414857,1.930837675632946,0.16216987090011553,0.6661166045339998,0.001617352823824191,0.3949590324162235,0.4453447000259606,0.13570438202306856,1.2572514626291789,1.4484086529903741,2.270451887980421,0.18851682862821462,0.16216987090011553,0.028667653788611115,3.4405094326495345,-0.3603686262084453,-0.16309171563110678,-0.6811632058277461,-0.08022423571315228,-0.2469724530743794,0.028667653788611115,1.1262641794309365,2.1964492630808774,0.001617352823824191,0.13570438202306856,-0.08022423571315228,0.5199959431965512,-0.19093998781040267,-0.025548389325393668,-0.16309171563110678,0.16216987090011553,0.3695803896161305,0.642046718499613,0.544638339789795,-0.3603686262084453,0.05560201529260138,0.8082816835493837,0.10912089420536077,0.4703509047116417,0.6661166045339998,0.3695803896161305,1.014770461288004,-0.5630118383388776,0.3695803896161305,1.6741322290310687,0.6178655297596958,-0.8312150461506137,-0.8009966357602808,-0.5337396628232933,-0.7708818840672291,0.544638339789795,0.10912089420536077,0.13570438202306856,-0.025548389325393668,0.2147447157493263,0.13570438202306856
3,401
Protease
13
88
2.536968
0.011182
P28072,P42785,P67812,P55786,Q9HB40,Q9UIQ6,Q96FZ2,Q9H3G5,P81605,O14773,O75844,P28074,P40818
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
194,73,42,170,12,76,17,209,216,22,122,59,220
1840,1604,22,639,1892,122,727,2102,2878,2105,1764,507,905,2907,2377,1315,2191,194,59,2604,1949,2754,220,2345,73,355,1471,1772,644,740,1566,2607,2518,2154,1903,1373,3168,170,1776,42,1778,216,2522,564,2731,281,3223,810,1273,1334,2763,3184,959,2214,1097,686,2864,892,818,1440,1395,17,1141,2583,996,1286,790,2413,1644,1588,456,209,2224,2743,520,12,1693,1880,1599,2986,1836,1985,76,723,2327,3022,2328,2329
-0.10773337464269757,0.028667653788611115,3.4405094326495345,0.642046718499613,-0.135356023882502,1.7938933718647914,0.5691629585556126,-0.2469724530743794,-0.8009966357602808,-0.2469724530743794,-0.05282908073775324,0.8082816835493837,0.4453447000259606,-0.8312150461506137,-0.41772541135227015,0.18851682862821462,-0.30344983319990226,1.4484086529903741,2.270451887980421,-0.5630118383388776,-0.16309171563110678,-0.6811632058277461,1.3642073059600701,-0.3889924804727667,2.1404139980394676,1.014770461288004,0.10912089420536077,-0.05282908073775324,0.642046718499613,0.5691629585556126,0.05560201529260138,-0.5630118383388776,-0.5045745330084603,-0.27515574959433703,-0.135356023882502,0.16216987090011553,-1.2966959112582077,1.5725549938573544,-0.05282908073775324,2.7160278165306524,-0.05282908073775324,1.385368830001817,-0.5045745330084603,0.7376735390494176,-0.6514667327479815,1.1702575091989806,-1.4246060531713614,0.5199959431965512,0.2147447157493263,0.18851682862821462,-0.6811632058277461,-1.328526673320553,0.42021400684349175,-0.30344983319990226,0.3184545058121038,0.6178655297596958,-0.7708818840672291,0.4703509047116417,0.5199959431965512,0.13570438202306856,0.16216987090011553,3.549836075975699,0.2927084466196836,-0.5337396628232933,0.3949590324162235,0.2147447157493263,0.544638339789795,-0.41772541135227015,0.028667653788611115,0.05560201529260138,0.9010133357750852,1.4064557073170705,-0.30344983319990226,-0.6514667327479815,0.8082816835493837,3.703522774064278,0.001617352823824191,-0.10773337464269757,0.05560201529260138,-0.8919614192603897,-0.08022423571315228,-0.16309171563110678,2.1404139980394676,0.5935714761388575,-0.3603686262084453,-0.9531181920204688,-0.3603686262084453,-0.3603686262084453
3,401
Proximal tubulopathy
6
23
2.536331
0.011202
O75306,P00403,P03886,Q9Y6M9,O43676,Q9NPL8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,162,3,246,145,161
2498,145,974,226,292,1705,1081,162,3,2781,2434,2380,2691,1325,882,2400,2407,993,822,161,1545,2094,246
-0.5045745330084603,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.025548389325393668,0.3184545058121038,1.5930038530109396,4.544166984823674,-0.710964802828651,-0.44656700343867023,-0.41772541135227015,-0.6218757596842738,0.18851682862821462,0.4703509047116417,-0.41772541135227015,-0.41772541135227015,0.3949590324162235,0.5199959431965512,1.6133853485657363,0.08241993256639264,-0.21890038394992256,1.3002667781715258
3,401
Mitochondrial carrier protein [IPR002067]
6
11
2.524222
0.011595
O43808,Q9H936,P12235,Q9HC21,P12236,P53007
Sequence
InterPro Family
interpro_family
35,359,253,74,462,400
35,872,537,253,462,400,1057,2404,359,74,1697
2.8360067907741575,0.4703509047116417,0.7613131382611684,1.2572514626291789,0.8779778896871095,0.9467966825508827,0.3440786823573308,-0.41772541135227015,1.014770461288004,2.1404139980394676,0.001617352823824191
3,401
Parkinsons disease
21
55
2.524037
0.011602
P03886,P00846,P22695,P12235,O43676,P00403,P14406,P45880,O75380,O95139,Q16795,P24539,Q9Y277,P13073,P12236,O43674,O75306,Q9Y6M9,P21796,P51970,O95168
Processes and pathways
KEGG Pathways
msigdb_kegg
3,4,509,253,145,162,163,295,292,44,183,71,72,463,462,94,226,246,240,366,248
2498,666,1198,94,145,974,226,292,2472,1705,2808,44,248,1999,838,1081,162,4,3,537,2849,1850,1851,1256,253,462,463,163,3238,907,3143,2434,1368,240,1119,1947,509,71,3055,2380,1258,733,1621,2345,295,2383,1325,366,1777,2815,2698,183,2413,72,246
-0.5045745330084603,0.6178655297596958,0.2408529853896325,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,-0.7408711516403494,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,0.7613131382611684,-0.7708818840672291,-0.10773337464269757,-0.10773337464269757,0.2147447157493263,1.2572514626291789,0.8779778896871095,0.8779778896871095,1.5930038530109396,-1.4891452293299312,0.4453447000259606,-1.233329760418191,-0.44656700343867023,0.16216987090011553,1.3002667781715258,0.2927084466196836,-0.16309171563110678,0.8082816835493837,2.1591440513142732,-1.0456168391676224,-0.41772541135227015,0.2147447157493263,0.5691629585556126,0.028667653788611115,-0.3889924804727667,1.1262641794309365,-0.41772541135227015,0.18851682862821462,0.9922045075089839,-0.05282908073775324,-0.7408711516403494,-0.6218757596842738,1.4900722702883373,-0.41772541135227015,2.1591440513142732,1.3002667781715258
3,401
Oxidative phosphorylation
21
62
2.519863
0.01174
P03886,P00846,Q9H3K2,O43676,Q9BSK2,P00403,P14406,O75380,O95139,O75964,P61586,Q16795,P56134,P24539,P13073,O43674,O75306,Q9Y6M9,P30405,P51970,O95168
Processes and pathways
GO Biological process
msigdb_gobp
3,4,13,145,32,162,163,292,44,168,423,183,446,71,463,94,226,246,488,366,248
2498,666,1198,94,145,974,226,975,292,2472,1705,2808,168,44,248,1999,838,1081,162,4,3,671,2849,1850,2507,1256,463,163,619,3238,907,3143,2434,1368,509,71,3055,1804,2380,488,1258,733,1562,1621,1321,2383,1325,366,2942,446,2255,423,2698,183,956,783,2413,32,1981,13,3050,246
-0.5045745330084603,0.6178655297596958,0.2408529853896325,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,0.3949590324162235,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,-0.7408711516403494,1.5725549938573544,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,0.6178655297596958,-0.7708818840672291,-0.10773337464269757,-0.5045745330084603,0.2147447157493263,0.8779778896871095,1.5930038530109396,0.6661166045339998,-1.4891452293299312,0.4453447000259606,-1.233329760418191,-0.44656700343867023,0.16216987090011553,0.8082816835493837,2.1591440513142732,-1.0456168391676224,-0.08022423571315228,-0.41772541135227015,0.8316133279582852,0.2147447157493263,0.5691629585556126,0.05560201529260138,0.028667653788611115,0.18851682862821462,-0.41772541135227015,0.18851682862821462,0.9922045075089839,-0.8615367583845711,0.9010133357750852,-0.3318542687573309,0.9239525336517246,-0.6218757596842738,1.4900722702883373,0.42021400684349175,0.544638339789795,-0.41772541135227015,2.9540811147426025,-0.16309171563110678,3.6882822134218296,-1.0146826095408896,1.3002667781715258
3,401
Electron transport chain oxphos system in mitochondria
21
52
2.511435
0.012024
P03886,P00846,P22695,P12235,O43676,O75880,P00403,P14406,O75380,O95139,O75964,Q16795,P56134,P24539,P13073,P12236,O43674,O75306,Q9Y6M9,P51970,O95168
Processes and pathways
WikiPathways
msigdb_wp
3,4,509,253,145,28,162,163,292,44,168,183,446,71,463,462,94,226,246,366,248
2498,666,1198,94,145,974,226,292,2472,1705,28,2808,168,44,248,1999,838,1081,162,4,3,537,2849,1851,1256,253,462,463,163,3238,907,3143,2434,1368,1119,509,71,3055,2380,1258,733,1621,2383,1325,366,446,2255,2698,183,783,2956,246
-0.5045745330084603,0.6178655297596958,0.2408529853896325,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,3.020731201810017,-0.7408711516403494,1.5725549938573544,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,0.7613131382611684,-0.7708818840672291,-0.10773337464269757,0.2147447157493263,1.2572514626291789,0.8779778896871095,0.8779778896871095,1.5930038530109396,-1.4891452293299312,0.4453447000259606,-1.233329760418191,-0.44656700343867023,0.16216987090011553,0.2927084466196836,0.8082816835493837,2.1591440513142732,-1.0456168391676224,-0.41772541135227015,0.2147447157493263,0.5691629585556126,0.028667653788611115,-0.41772541135227015,0.18851682862821462,0.9922045075089839,0.9010133357750852,-0.3318542687573309,-0.6218757596842738,1.4900722702883373,0.544638339789795,-0.8615367583845711,1.3002667781715258
3,401
Pure red cell aplasia
11
21
2.511407
0.012025
P62847,P08708,P18077,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,331,109,234,149,367,402,339,221
2642,2964,508,444,2992,221,331,2111,402,367,109,339,843,773,297,234,1327,1376,1052,149,591
-0.5923906667876935,-0.8919614192603897,0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.7139285396999346
3,401
Purine containing compound transmembrane transport
6
9
2.507795
0.012149
O43808,P12235,P41440,Q8TB61,Q99808,P12236
Processes and pathways
GO Biological process
msigdb_gobp
35,253,70,140,274,462
1607,35,537,253,462,70,140,2705,274
0.028667653788611115,2.8360067907741575,0.7613131382611684,1.2572514626291789,0.8779778896871095,2.177822330333986,1.6942507925226085,-0.6218757596842738,1.1921286759414857
3,401
Oxidative phosphorylation
12
33
2.505465
0.012229
O75306,P03886,P00846,P24539,O75380,O75964,O95139,Q9Y6M9,Q16795,P51970,O95168,O43674
Processes and pathways
WikiPathways
msigdb_wp
226,3,4,71,292,168,44,246,183,366,248,94
2498,666,94,974,226,292,2472,1705,1762,2808,168,44,248,1999,838,1081,4,3,2849,3143,2434,71,3055,2380,2383,1325,366,446,2255,2574,2698,183,246
-0.5045745330084603,0.6178655297596958,2.0078167090146146,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,-0.05282908073775324,-0.7408711516403494,1.5725549938573544,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,4.4328621068997585,4.544166984823674,-0.7708818840672291,-1.233329760418191,-0.44656700343867023,2.1591440513142732,-1.0456168391676224,-0.41772541135227015,-0.41772541135227015,0.18851682862821462,0.9922045075089839,0.9010133357750852,-0.3318542687573309,-0.5337396628232933,-0.6218757596842738,1.4900722702883373,1.3002667781715258
3,401
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
19
62
2.503642
0.012292
P03886,P00846,Q8N8Q8,O43676,O75880,Q9NPL8,P00403,O75380,O95139,O75964,O43819,Q16795,P56134,P24539,O43674,O75306,Q9Y6M9,P51970,O95168
Processes and pathways
Reactome Pathways
msigdb_reactome
3,4,143,145,28,161,162,292,44,168,419,183,446,71,94,226,246,366,248
2498,666,1198,94,145,419,974,226,292,2472,1705,28,2808,168,44,248,1999,838,1081,162,4,3,2849,1850,1851,1256,463,2781,3238,907,3143,2434,1368,1119,509,71,3055,2380,1258,733,1621,2691,1807,2383,1325,366,446,2255,2789,2400,2698,183,2407,143,1593,1442,822,1294,161,1545,929,246
-0.5045745330084603,0.6178655297596958,0.2408529853896325,2.0078167090146146,1.6539488897454098,0.9239525336517246,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,3.020731201810017,-0.7408711516403494,1.5725549938573544,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,-0.7708818840672291,-0.10773337464269757,-0.10773337464269757,0.2147447157493263,0.8779778896871095,-0.710964802828651,-1.4891452293299312,0.4453447000259606,-1.233329760418191,-0.44656700343867023,0.16216987090011553,0.2927084466196836,0.8082816835493837,2.1591440513142732,-1.0456168391676224,-0.41772541135227015,0.2147447157493263,0.5691629585556126,0.028667653788611115,-0.6218757596842738,-0.08022423571315228,-0.41772541135227015,0.18851682862821462,0.9922045075089839,0.9010133357750852,-0.3318542687573309,-0.710964802828651,-0.41772541135227015,-0.6218757596842738,1.4900722702883373,-0.41772541135227015,1.6741322290310687,0.05560201529260138,0.13570438202306856,0.5199959431965512,0.2147447157493263,1.6133853485657363,0.08241993256639264,0.4453447000259606,1.3002667781715258
3,401
rRNA-binding
8
19
2.503458
0.012299
P62280,P61927,O75616,P46777,P62701,P62917,Q9Y2R5,P46781
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
447,189,262,331,233,113,328,279
262,331,279,189,705,447,233,540,1052,113,1685,1528,2169,1394,1001,1297,2771,2675,328
1.2356247347543958,1.059631974750273,1.1702575091989806,1.4692762530118126,0.5935714761388575,0.9010133357750852,1.32165710213149,0.7613131382611684,0.3440786823573308,1.8333179734584413,0.001617352823824191,0.08241993256639264,-0.27515574959433703,0.16216987090011553,0.3949590324162235,0.2147447157493263,-0.6811632058277461,-0.5923906667876935,1.0819296780167726
3,401
Polyneuropathy
6
22
2.48776
0.012855
P03886,P00846,Q15041,Q9HC21,O95831,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,4,37,74,46,285
2747,3177,46,1846,4,3,670,2643,2753,287,733,1319,1859,3229,2612,37,2571,1867,2979,74,285,2988
-0.6811632058277461,-1.328526673320553,2.664001817387791,-0.10773337464269757,4.4328621068997585,4.544166984823674,0.6178655297596958,-0.5923906667876935,-0.6811632058277461,1.1483029978313013,0.5691629585556126,0.18851682862821462,-0.10773337464269757,-1.4568272125871744,-0.5630118383388776,2.8189856921283467,-0.5337396628232933,-0.10773337464269757,-0.8919614192603897,2.1404139980394676,1.1702575091989806,-0.8919614192603897
3,401
Inner mitochondrial membrane protein complex
23
77
2.478941
0.013177
P03886,P00846,O43676,P00403,P14406,O95139,O75964,O75380,Q16795,Q5XKP0,P56134,P24539,P13073,P12236,O60830,Q13505,P62072,O43674,O75306,Q9Y6M9,Q9Y584,P51970,O95168
Localization
GO Cellular component
msigdb_gocc
3,4,145,162,163,44,168,292,183,450,446,71,463,462,458,480,93,94,226,246,245,366,248
2498,666,1198,1606,94,145,458,974,226,292,2749,2472,1705,2808,168,44,248,1999,838,1081,162,4,3,2849,1850,1851,1256,462,463,163,3238,907,3143,2434,1368,1119,509,71,3055,2380,1258,733,2783,1621,3056,2383,1325,366,446,2255,93,480,2698,183,2450,1093,2078,1784,450,987,1435,1974,993,1686,2035,2456,3346,2835,633,3081,929,830,2328,1149,245,1503,246
-0.5045745330084603,0.6178655297596958,0.2408529853896325,0.028667653788611115,2.0078167090146146,1.6539488897454098,0.8779778896871095,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.6811632058277461,-0.4755168460231504,-0.025548389325393668,-0.7408711516403494,1.5725549938573544,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,-0.7708818840672291,-0.10773337464269757,-0.10773337464269757,0.2147447157493263,0.8779778896871095,0.8779778896871095,1.5930038530109396,-1.4891452293299312,0.4453447000259606,-1.233329760418191,-0.44656700343867023,0.16216987090011553,0.2927084466196836,0.8082816835493837,2.1591440513142732,-1.0456168391676224,-0.41772541135227015,0.2147447157493263,0.5691629585556126,-0.710964802828651,0.028667653788611115,-1.0456168391676224,-0.41772541135227015,0.18851682862821462,0.9922045075089839,0.9010133357750852,-0.3318542687573309,2.0269216832537302,0.8548449707097387,-0.6218757596842738,1.4900722702883373,-0.44656700343867023,0.3184545058121038,-0.21890038394992256,-0.05282908073775324,0.9010133357750852,0.3949590324162235,0.13570438202306856,-0.16309171563110678,0.3949590324162235,0.001617352823824191,-0.19093998781040267,-0.44656700343867023,-2.1554148991440814,-0.7408711516403494,0.6661166045339998,-1.0766519715520646,0.4453447000259606,0.5199959431965512,-0.3603686262084453,0.2927084466196836,1.3002667781715258,0.10912089420536077,1.3002667781715258
3,401
Network map of sarscov2 signaling pathway
14
31
2.468865
0.013554
P14635,Q9NYZ3,P42345,P07858,Q53FA7,P62753,P31350,Q8N122,Q9P253,Q96J02,Q14240,Q9UHD2,Q96B36,Q9H269
Processes and pathways
WikiPathways
msigdb_wp
619,131,539,507,426,110,489,493,313,628,120,551,518,689
2146,1077,671,1311,1764,507,2683,619,489,2194,539,2345,1775,110,1262,1266,1779,120,426,1058,2791,1388,493,1823,518,628,1740,689,131,313,551
-0.27515574959433703,0.3184545058121038,0.6178655297596958,0.18851682862821462,-0.05282908073775324,0.8082816835493837,-0.6218757596842738,0.6661166045339998,0.8316133279582852,-0.30344983319990226,0.7613131382611684,-0.3889924804727667,-0.05282908073775324,1.872502281604809,0.2147447157493263,0.2147447157493263,-0.05282908073775324,1.8136359864985119,0.9239525336517246,0.3440786823573308,-0.710964802828651,0.16216987090011553,0.8316133279582852,-0.08022423571315228,0.8082816835493837,0.6661166045339998,-0.025548389325393668,0.6178655297596958,1.7542239904369825,1.1041400729155888,0.7613131382611684
3,401
Secondary active transmembrane transporter activity
11
24
2.464282
0.013729
Q9H936,P12235,P05141,P53985,P41440,O00400,O95202,Q02978,P12236,Q9UBX3,P53007
Functions
GO Molecular function
msigdb_gomf
359,253,537,133,70,11,293,332,462,121,400
11,293,1801,537,2003,253,462,70,2198,3320,1217,400,133,1809,741,332,655,2790,1974,1445,1233,359,121,866
3.8544190981954287,1.1262641794309365,-0.08022423571315228,0.7613131382611684,-0.19093998781040267,1.2572514626291789,0.8779778896871095,2.177822330333986,-0.30344983319990226,-1.884412751971023,0.2408529853896325,0.9467966825508827,1.7143052013527764,-0.08022423571315228,0.5691629585556126,1.059631974750273,0.642046718499613,-0.710964802828651,-0.16309171563110678,0.13570438202306856,0.2408529853896325,1.014770461288004,1.8136359864985119,0.49523405136401416
3,401
Organic aciduria
9
37
2.464193
0.013732
Q4G176,P12235,Q9HC21,P08397,Q96RQ3,O43772,P48735,P23786,O75880
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
132,253,74,232,410,47,19,364,28
47,28,1081,1364,2431,232,1557,253,2781,1369,364,1858,910,2691,1214,19,2384,1124,2113,1518,400,1126,984,2400,1383,2699,132,1684,1822,1346,410,1294,1745,74,2542,2462,1749
2.629109857257126,3.020731201810017,0.3184545058121038,0.16216987090011553,-0.44656700343867023,1.32165710213149,0.05560201529260138,1.2572514626291789,-0.710964802828651,0.16216987090011553,0.9922045075089839,-0.10773337464269757,0.4453447000259606,-0.6218757596842738,0.2408529853896325,3.53430786323273,-0.41772541135227015,0.2927084466196836,-0.2469724530743794,0.08241993256639264,0.9467966825508827,0.2927084466196836,0.3949590324162235,-0.41772541135227015,0.16216987090011553,-0.6218757596842738,1.7342960667860914,0.001617352823824191,-0.08022423571315228,0.18851682862821462,0.9467966825508827,0.2147447157493263,-0.025548389325393668,2.1404139980394676,-0.5045745330084603,-0.44656700343867023,-0.025548389325393668
3,401
Abnormal metabolic brain imaging by mrs
6
16
2.440701
0.014659
P35610,O75306,P00403,P03886,O43819,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
157,226,162,3,419,285
1248,525,419,226,162,3,2643,1206,1119,2810,157,1126,1680,1738,822,285
0.2147447157493263,0.7848487317778781,0.9239525336517246,1.3429703349028668,1.5930038530109396,4.544166984823674,-0.5923906667876935,0.2408529853896325,0.2927084466196836,-0.7408711516403494,1.6133853485657363,0.2927084466196836,0.001617352823824191,-0.025548389325393668,0.5199959431965512,1.1702575091989806
3,401
Normochromic anemia
11
24
2.439826
0.014694
P62847,P08708,P18077,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,331,109,234,149,367,402,339,221
1203,2001,508,444,1465,2992,221,331,2111,2442,402,367,109,339,843,773,297,234,1327,1376,1052,2726,149,591
0.2408529853896325,-0.19093998781040267,0.8082816835493837,0.9010133357750852,0.10912089420536077,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,-0.44656700343867023,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,-0.6514667327479815,1.6539488897454098,0.7139285396999346
3,401
Glycerophospholipid metabolism
7
20
2.436045
0.014849
Q9HBU6,Q96N66,P35790,Q9HCL2,O15228,O95674,O14735
Processes and pathways
KEGG Pathways
msigdb_kegg
136,237,14,111,212,336,127
127,212,1156,336,1461,14,1771,1122,1092,3378,989,1341,1582,453,237,1589,3019,136,111,1986
1.7542239904369825,1.385368830001817,0.2668410830881398,1.037245922867657,0.10912089420536077,3.642391628326361,-0.05282908073775324,0.2927084466196836,0.3184545058121038,-2.7863373702683543,0.3949590324162235,0.18851682862821462,0.05560201529260138,0.9010133357750852,1.32165710213149,0.05560201529260138,-0.9531181920204688,1.7143052013527764,1.852939889172417,-0.16309171563110678
3,401
Adenocarcinoma of the intestines
12
25
2.434573
0.014909
P62847,P08708,P18077,Q969E8,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,591,331,109,234,149,367,402,339,221
508,444,2379,1257,2992,221,1321,331,2111,402,367,109,339,843,773,297,234,1327,1376,1052,880,149,606,2352,591
0.8082816835493837,0.9010133357750852,-0.41772541135227015,0.2147447157493263,-0.9224886791663648,1.3642073059600701,0.18851682862821462,1.059631974750273,-0.2469724530743794,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,0.4703509047116417,1.6539488897454098,0.6900767143139638,-0.3889924804727667,0.7139285396999346
3,401
Duplication of thumb phalanx
15
25
2.430989
0.015058
Q8WVQ1,P08708,P62847,Q9BXW9,P18077,Q969E8,P46777,P61313,P62854,P62244,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
787,508,297,762,444,591,331,109,234,773,149,367,402,339,221
508,444,1562,2992,2058,221,331,2111,2441,402,367,109,339,843,773,297,234,1327,1376,1052,149,787,591,762,2713
0.8082816835493837,0.9010133357750852,0.05560201529260138,-0.9224886791663648,-0.21890038394992256,1.3642073059600701,1.059631974750273,-0.2469724530743794,-0.44656700343867023,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,1.6539488897454098,0.544638339789795,0.7139285396999346,0.5691629585556126,-0.6218757596842738
3,401
Mitochondrial complex iv assembly
7
13
2.429522
0.015119
P00403,P14406,O00483,Q8N8Q8,O43819,P13073,Q9Y2R0
Processes and pathways
WikiPathways
msigdb_wp
162,163,666,143,419,463,24
666,419,162,1851,1256,463,163,907,1368,783,143,1442,24
0.6178655297596958,0.9239525336517246,1.5930038530109396,-0.10773337464269757,0.2147447157493263,0.8779778896871095,1.5930038530109396,0.4453447000259606,0.16216987090011553,0.544638339789795,1.6741322290310687,0.13570438202306856,3.2334307204873185
3,401
Developmental glaucoma
16
27
2.420888
0.015483
Q8WVQ1,P08708,P62847,Q14118,P18077,Q969E8,P46777,P61313,P62854,P62244,Q07020,P61254,P60866,P61353,P62081,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
787,508,297,356,444,591,331,109,234,773,149,367,402,339,843,221
508,444,1415,1013,2992,221,331,2111,2253,402,367,109,339,843,773,297,234,1327,1376,1052,882,149,356,787,591,2134,1194
0.8082816835493837,0.9010133357750852,0.13570438202306856,0.3695803896161305,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,-0.3318542687573309,0.9467966825508827,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,0.4703509047116417,1.6539488897454098,1.014770461288004,0.544638339789795,0.7139285396999346,-0.2469724530743794,0.2668410830881398
3,401
Respiratory chain
10
30
2.419906
0.015525
O75306,P00403,P03886,O75380,O95139,Q9Y6M9,Q16795,O43676,O95168,O43674
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
226,162,3,292,44,246,183,145,248,94
2498,666,94,145,974,226,292,2472,1705,44,248,1999,838,1081,162,3,1850,3238,2434,509,2380,733,1325,366,2698,183,955,993,929,246
-0.5045745330084603,0.6178655297596958,2.0078167090146146,1.6539488897454098,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.4755168460231504,-0.025548389325393668,2.6813851107199134,1.2787985183948616,-0.19093998781040267,0.49523405136401416,0.3184545058121038,1.5930038530109396,4.544166984823674,-0.10773337464269757,-1.4891452293299312,-0.44656700343867023,0.8082816835493837,-0.41772541135227015,0.5691629585556126,0.18851682862821462,0.9922045075089839,-0.6218757596842738,1.4900722702883373,0.42021400684349175,0.3949590324162235,0.4453447000259606,1.3002667781715258
3,401
Regulation of cholesterol biosynthesis by srebp srebf
7
26
2.385515
0.017055
Q15648,O75845,Q9UBM7,O00767,Q9HCL2,Q16850,P48449
Processes and pathways
Reactome Pathways
msigdb_reactome
357,316,39,138,111,53,125
2776,138,316,1079,1610,443,1464,2008,125,1324,2064,805,2693,984,680,1523,1781,2617,1633,357,53,1021,2584,1742,111,39
-0.710964802828651,1.6942507925226085,1.0819296780167726,0.3184545058121038,0.028667653788611115,0.9010133357750852,0.10912089420536077,-0.19093998781040267,1.7740895644817878,0.18851682862821462,-0.21890038394992256,0.5199959431965512,-0.6218757596842738,0.3949590324162235,0.6178655297596958,0.08241993256639264,-0.05282908073775324,-0.5630118383388776,0.028667653788611115,1.014770461288004,2.487824819755659,0.3695803896161305,-0.5337396628232933,-0.025548389325393668,1.852939889172417,2.8019254667161024
3,401
Increased mean corpuscular volume
11
25
2.327155
0.019957
P62847,P08708,P18077,P46777,P61313,P62854,Q07020,P61254,P60866,P61353,P42766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,508,444,331,109,234,149,367,402,339,221
508,444,2992,221,331,2111,402,1718,367,109,339,843,773,297,234,1327,1376,1052,1086,149,2026,1433,591,3171,1653
0.8082816835493837,0.9010133357750852,-0.9224886791663648,1.3642073059600701,1.059631974750273,-0.2469724530743794,0.9467966825508827,-0.025548389325393668,0.9922045075089839,1.872502281604809,1.037245922867657,0.49523405136401416,0.544638339789795,1.1262641794309365,1.32165710213149,0.18851682862821462,0.16216987090011553,0.3440786823573308,0.3184545058121038,1.6539488897454098,-0.19093998781040267,0.13570438202306856,0.7139285396999346,-1.2966959112582077,0.028667653788611115
3,401
Intrinsic component of mitochondrial inner membrane
12
34
2.32686
0.019973
O60830,Q15070,Q9HC21,Q9H3K2,Q8N8Q8,O43819,Q6P4A7,Q9Y2R0,Q13505,P17152,O75880,Q5XKP0
Localization
GO Cellular component
msigdb_gocc
458,104,74,13,143,419,514,24,480,219,28,450
1606,419,458,2749,28,506,219,3056,1124,741,480,104,2400,2450,2078,1784,450,514,987,143,1974,3047,894,2035,13,1692,1745,74,633,3081,1986,24,2328,1149
0.028667653788611115,0.9239525336517246,0.8779778896871095,-0.6811632058277461,3.020731201810017,0.8082816835493837,1.3642073059600701,-1.0456168391676224,0.2927084466196836,0.5691629585556126,0.8548449707097387,1.9114506472351467,-0.41772541135227015,-0.44656700343867023,-0.21890038394992256,-0.05282908073775324,0.9010133357750852,0.8082816835493837,0.3949590324162235,1.6741322290310687,-0.16309171563110678,-1.0146826095408896,0.4703509047116417,-0.19093998781040267,3.6882822134218296,0.001617352823824191,-0.025548389325393668,2.1404139980394676,0.6661166045339998,-1.0766519715520646,-0.16309171563110678,3.2334307204873185,-0.3603686262084453,0.2927084466196836
3,401
Increased csf lactate
15
48
2.326654
0.019984
O75306,P00403,P03886,P00846,Q9HC21,O75380,O95831,Q9Y6M9,O43819,P13073,Q16795,O43676,P51970,P82930,Q9NPL8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,162,3,4,74,292,46,246,419,463,183,145,366,340,161
2498,666,145,419,974,226,292,1705,838,46,1081,162,4,3,1661,463,2434,2380,2648,1258,2754,2692,1807,1325,3011,366,1126,340,183,1682,1867,783,1387,2407,2454,517,2949,993,2271,1738,1442,822,74,161,597,1545,929,246
-0.5045745330084603,0.6178655297596958,1.6539488897454098,0.9239525336517246,0.3949590324162235,1.3429703349028668,1.1262641794309365,-0.025548389325393668,0.49523405136401416,2.664001817387791,0.3184545058121038,1.5930038530109396,4.4328621068997585,4.544166984823674,0.001617352823824191,0.8779778896871095,-0.44656700343867023,-0.41772541135227015,-0.5923906667876935,0.2147447157493263,-0.6811632058277461,-0.6218757596842738,-0.08022423571315228,0.18851682862821462,-0.9531181920204688,0.9922045075089839,0.2927084466196836,1.037245922867657,1.4900722702883373,0.001617352823824191,-0.10773337464269757,0.544638339789795,0.16216987090011553,-0.41772541135227015,-0.44656700343867023,0.8082816835493837,-0.8615367583845711,0.3949590324162235,-0.3318542687573309,-0.025548389325393668,0.13570438202306856,0.5199959431965512,2.1404139980394676,1.6133853485657363,0.7139285396999346,0.08241993256639264,0.4453447000259606,1.3002667781715258
3,401