term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Splenomegaly | 30 | 79 | 2.988581 | 0.002803 | P16930,Q14739,O00754,Q13510,P36551,P16278,Q15392,P00813,Q14108,P33991,Q96A33,P04066,P07602,P04062,Q96HY6,P11166,P21964,P15586,Q9NZJ7,Q9BT22,P31749,Q10713,P28070,Q9NZ08,P14174,P10253,O15118,P51798,Q96AD5,P54802 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 506,260,502,6,520,16,281,20,22,276,418,295,43,171,439,310,317,187,457,195,196,197,463,341,80,218,93,101,240,113 | 2648,2458,2330,502,2421,738,93,1382,2115,2558,1197,2066,1835,20,1979,171,295,2653,1198,3003,1384,2119,43,218,310,2463,2685,1014,2686,80,187,16,506,2337,1246,317,1733,2771,463,986,2532,196,276,520,2296,1933,1602,2248,1253,101,1996,1649,113,2935,870,1058,197,682,3010,6,934,22,260,281,2046,768,2402,1807,1562,2639,418,240,1666,439,547,195,2549,341,457 | -0.7489239882266361,-0.606267828635831,-0.5358936496388635,0.6160695351919047,-0.5827403002940941,0.3060621463513644,2.35701295367094,-0.10401912304964674,-0.44302020696238215,-0.6772732957307089,-0.01596607463826186,-0.4199698464474526,-0.3057028045175211,3.890193613688759,-0.3740674450103724,1.7190419968762196,1.1470081486218546,-0.7489239882266361,-0.01596607463826186,-2.0250500657604884,-0.10401912304964674,-0.44302020696238215,3.154426526604387,1.409965539103894,1.0896107895774603,-0.606267828635831,-0.7729534155941898,0.09278259830834672,-0.7729534155941898,2.5546987479486667,1.5930794075923984,3.9467246428005365,0.6160695351919047,-0.5358936496388635,-0.037890347716938104,1.070393382836239,-0.2604471495603937,-0.8698150771053541,0.69684344960622,0.11436040160061789,-0.6535338132122217,1.5385430296065519,1.2040279643762803,0.5957548236023519,-0.5125735357359387,-0.35121448743560607,-0.1930361462854971,-0.48932157771479984,-0.037890347716938104,2.273374172038848,-0.3740674450103724,-0.21544405120141735,2.120868736002922,-1.2698263697676262,0.20011058306743956,0.07114797485870293,1.5385430296065519,0.36899000714620145,-2.1684205196784307,4.797294388390134,0.15734698889488374,3.7041893683460807,1.2606762141367405,1.2040279643762803,-0.39698574608401843,0.2849798960714869,-0.5592824068345678,-0.2830431922681599,-0.17069011224710406,-0.724967851906094,0.7768548054179463,1.3356392751731447,-0.21544405120141735,0.7369433540186023,0.5549779266548395,1.5567592001978614,-0.6535338132122217,0.9930928138653216,0.7169170935451981 | 3,039 |
Alzheimers disease and mirna effects | 20 | 89 | 2.983426 | 0.00285 | P21796,P49721,P45880,P31751,Q9BVA1,Q9Y277,Q13885,P04350,Q92542,P31749,P20618,Q9BUF5,P28072,P07437,P16615,P27361,Q9NQC3,O95197,P68371,P14735 | Processes and pathways | WikiPathways | msigdb_wp | 4,130,7,268,153,294,168,167,183,196,207,222,224,105,233,237,127,112,124,249 | 1473,2833,656,1293,1346,1195,2459,2332,1632,838,112,167,2068,757,306,1926,105,759,721,249,233,2852,983,1785,1989,207,4,790,2240,1482,1685,2466,237,1840,463,224,374,2428,196,268,891,743,2243,955,792,1896,7,1787,892,1602,924,130,1995,2299,567,469,1212,1021,2300,2633,124,745,2254,931,555,797,1941,2209,2474,168,1611,2661,801,2754,183,399,753,2054,2317,2668,222,153,908,127,1157,2675,1522,294,1584 | -0.14840553567250234,-0.9678943672344994,0.3898607435766084,-0.059873687391535715,-0.08191648177571846,-0.01596607463826186,-0.606267828635831,-0.5358936496388635,-0.21544405120141735,0.22140963170165096,2.120868736002922,1.736891982086496,-0.4199698464474526,0.2849798960714869,1.1087855671016753,-0.35121448743560607,2.205908584221655,0.2849798960714869,0.32709103081034985,1.2982381726059844,1.3542800263786563,-0.9926088412170806,0.11436040160061789,-0.2830431922681599,-0.3740674450103724,1.483667990965456,5.053064615984644,0.26384394974348613,-0.48932157771479984,-0.14840553567250234,-0.23791424484342957,-0.606267828635831,1.3356392751731447,-0.3057028045175211,0.69684344960622,1.3914429554854009,0.875822884605927,-0.5827403002940941,1.5385430296065519,1.2229517085712236,0.17875648445362774,0.3060621463513644,-0.48932157771479984,0.13588174593938243,0.26384394974348613,-0.3284264225634382,4.548247176509721,-0.2830431922681599,0.17875648445362774,-0.1930361462854971,0.15734698889488374,2.0004591255918744,-0.3740674450103724,-0.5125735357359387,0.5140024586389151,0.6767221488954713,-0.01596607463826186,0.09278259830834672,-0.5125735357359387,-0.724967851906094,2.0694603911174667,0.3060621463513644,-0.48932157771479984,0.15734698889488374,0.5345151608497005,0.26384394974348613,-0.35121448743560607,-0.46613729363893336,-0.606267828635831,1.736891982086496,-0.1930361462854971,-0.7489239882266361,0.26384394974348613,-0.8454869482570131,1.6652764555563804,0.8363732981403815,0.3060621463513644,-0.39698574608401843,-0.5125735357359387,-0.7489239882266361,1.409965539103894,1.8608535136088946,0.17875648445362774,2.0350255192397007,0.027706804197958748,-0.7489239882266361,-0.14840553567250234,1.166056404831489,-0.17069011224710406 | 3,039 |
Azurophil granule membrane | 9 | 19 | 2.978159 | 0.0029 | P27105,Q07065,P07602,P42785,P51809,P13473,Q92542,P10253,O15260 | Localization | GO Cellular component | msigdb_gocc | 234,202,43,47,367,111,183,218,27 | 27,1588,2288,43,218,607,111,234,2129,47,763,367,202,846,710,183,1111,457,1338 | 3.6025482837872342,-0.1930361462854971,-0.5125735357359387,3.154426526604387,1.409965539103894,0.4521617483820871,2.137940388935406,1.3542800263786563,-0.44302020696238215,3.123793940195311,0.2849798960714869,0.895479624968376,1.5019976151465506,0.22140963170165096,0.34806687646145595,1.6652764555563804,0.04945616636338176,0.7169170935451981,-0.059873687391535715 | 3,039 |
Transport vesicle | 25 | 86 | 2.972549 | 0.002953 | P24390,O43760,P49755,O95249,Q7L0J3,P49257,P20339,O75396,O15260,P50897,O43752,Q9NR31,Q9Y3B3,Q92542,Q96A57,Q15363,Q9BT78,Q15286,P51790,Q86Y82,P51809,P61020,O76024,Q9BVK6,O00461 | Localization | GO Cellular component | msigdb_gocc | 1,257,387,262,395,269,405,275,27,31,541,562,309,183,185,65,455,337,219,362,367,368,484,381,121 | 1381,121,859,1082,27,549,1163,2628,541,257,755,1881,1831,275,1636,484,2740,262,1167,1637,1727,1087,863,864,607,787,760,627,405,1641,583,1,1483,1302,1392,2194,1207,269,387,31,896,1935,219,367,2783,2250,1996,1054,368,1210,1055,844,1097,680,2136,820,1609,2092,845,2536,726,337,2262,65,1136,395,1697,362,1419,183,1422,971,185,455,381,878,1287,562,2487,1578,2416,2645,309,2367,1008,914 | -0.10401912304964674,2.0866288849685453,0.20011058306743956,0.04945616636338176,3.6025482837872342,0.5345151608497005,0.005899515949245535,-0.724967851906094,0.5549779266548395,1.2794774054002804,0.2849798960714869,-0.3284264225634382,-0.3057028045175211,1.2040279643762803,-0.21544405120141735,0.6363354713395758,-0.8454869482570131,1.2418343865431385,0.005899515949245535,-0.21544405120141735,-0.2604471495603937,0.04945616636338176,0.20011058306743956,0.20011058306743956,0.4521617483820871,0.26384394974348613,0.2849798960714869,0.4314463011221435,0.7967405306725779,-0.21544405120141735,0.4934395229159375,5.339593503895038,-0.14840553567250234,-0.059873687391535715,-0.10401912304964674,-0.46613729363893336,-0.01596607463826186,1.2229517085712236,0.856120860427004,3.470285289418032,0.17875648445362774,-0.35121448743560607,1.409965539103894,0.895479624968376,-0.8942192990435678,-0.48932157771479984,-0.3740674450103724,0.07114797485870293,0.895479624968376,-0.01596607463826186,0.07114797485870293,0.22140963170165096,0.04945616636338176,0.36899000714620145,-0.44302020696238215,0.24265397388246301,-0.1930361462854971,-0.4199698464474526,0.22140963170165096,-0.6535338132122217,0.32709103081034985,0.9930928138653216,-0.48932157771479984,2.748257927082434,0.027706804197958748,0.8363732981403815,-0.23791424484342957,0.9150913335574359,-0.10401912304964674,1.6652764555563804,-0.10401912304964674,0.13588174593938243,1.629251338660244,0.7169170935451981,0.875822884605927,0.20011058306743956,-0.037890347716938104,0.5345151608497005,-0.606267828635831,-0.17069011224710406,-0.5592824068345678,-0.724967851906094,1.1087855671016753,-0.5358936496388635,0.11436040160061789,0.17875648445362774 | 3,039 |
Organic acid transmembrane transport | 19 | 32 | 2.965565 | 0.003021 | O43772,P31751,Q9Y289,Q96QD8,Q02978,O75915,Q9UJS0,P53985,Q9H2J7,P11166,Q9H936,P31749,Q9UBX3,O60831,P08183,P23786,Q9H2D1,Q9Y619,P50416 | Processes and pathways | GO Biological process | msigdb_gobp | 129,268,540,270,529,542,164,412,442,310,456,196,77,582,107,108,120,382,245 | 779,129,582,1085,542,2704,1200,107,783,310,108,986,196,268,2429,2654,245,723,412,529,749,900,875,270,120,442,456,641,77,164,540,382 | 0.26384394974348613,2.0004591255918744,0.4934395229159375,0.04945616636338176,0.5549779266548395,-0.7970566811673792,-0.01596607463826186,2.1719878809978588,0.26384394974348613,1.0896107895774603,2.154980055528231,0.11436040160061789,1.5385430296065519,1.2229517085712236,-0.5827403002940941,-0.7489239882266361,1.3169587262701798,0.32709103081034985,0.7768548054179463,0.5753910503793658,0.3060621463513644,0.17875648445362774,0.20011058306743956,1.2229517085712236,2.1037649504595,0.7369433540186023,0.7169170935451981,0.4314463011221435,2.603467193814167,1.7902287843769074,0.5753910503793658,0.875822884605927 | 3,039 |
Ragged red muscle fibers | 7 | 19 | 2.964968 | 0.003027 | P03886,Q70HW3,O95831,Q9Y276,Q7LG56,Q9H2D1,P00846 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 38,137,74,144,212,120,63 | 1831,74,226,63,38,759,2340,1313,2746,746,1804,137,212,558,379,1149,120,144,1343 | -0.3057028045175211,2.651981080000916,1.3728811852532863,2.7642080742589887,3.275983050297943,0.2849798960714869,-0.5358936496388635,-0.059873687391535715,-0.8454869482570131,0.3060621463513644,-0.2830431922681599,1.9309268460754112,1.4653001660607239,0.5345151608497005,0.875822884605927,0.027706804197958748,2.1037649504595,1.9134596354218771,-0.059873687391535715 | 3,039 |
Golgi apparatus | 90 | 298 | 2.951439 | 0.003163 | P24390,O43852,P16278,Q14108,O15260,O15258,Q96RL7,P50897,P80303,O43752,O15127,Q9Y3A6,Q9NR31,O15498,O43505,Q9NPR9,Q15363,Q96PU5,Q8TB61,Q8NCH0,Q9P2W9,O75503,O15118,Q5VW38,Q8N4V1,Q8IV08,O95197,O00461,O75695,Q92504,Q93050,Q9H2C2,P04062,Q9HC07,Q92542,Q96A57,P06280,Q9NX62,Q10713,Q10472,Q8NBJ4,Q9UQB8,Q9Y282,Q8NBN3,P51790,O14773,P27361,P51572,Q16739,O95249,P49257,Q9H7Z7,Q15392,Q9Y3E0,P35613,O75396,Q92520,O95070,Q02818,Q5T9L3,Q9Y3B3,P11166,Q9UM00,Q9NX40,P05023,Q8IZA0,Q8NEW0,Q9BTU6,Q86Y82,P51809,Q9BVK6,P53367,Q8TD16,P49755,Q13596,Q96S66,Q6ZRP7,Q4J6C6,P54646,Q9UP83,Q15642,O95456,Q8N3F8,L0R6Q1,Q96M27,Q9C0D9,Q9UID3,Q9NTJ5,Q7LGA3,Q7Z3D4 | Localization | GO Cellular component | msigdb_gocc | 1,503,16,22,27,526,547,31,33,541,36,564,562,549,550,53,65,70,72,75,82,94,93,95,99,103,112,121,122,131,136,163,171,174,183,185,191,193,197,203,204,210,213,215,219,231,237,251,265,262,269,271,281,283,277,275,293,287,300,307,309,310,323,326,334,339,345,363,362,367,381,376,388,387,394,410,416,414,413,444,438,434,451,459,479,480,500,498,492,510 | 459,2458,1381,2330,121,859,2421,2909,1972,231,674,1431,1082,93,36,526,27,549,1778,2237,1163,550,2628,541,2585,1238,503,696,755,1881,2461,275,94,1682,1636,122,287,112,262,1590,1048,434,1726,1727,3028,171,1087,334,191,1242,2683,2070,1385,863,2998,864,310,787,16,2852,951,1442,627,1641,583,2878,1124,2706,3008,1,790,1126,237,2771,2494,1930,1390,1735,1392,277,1600,1932,955,1645,792,2080,2430,647,1207,2597,269,1602,387,1448,925,2248,31,896,1935,251,219,367,1357,2249,376,2783,2250,630,413,2903,2040,1650,1054,898,1210,1055,1097,1548,2981,680,1316,869,33,870,1495,2136,1552,2254,300,555,991,1748,1365,203,2257,197,820,1059,765,632,1609,2304,2092,2473,394,1693,2002,22,1319,993,2004,2603,1101,2693,2983,1906,2260,2262,65,2213,281,1136,438,1413,265,414,307,1757,95,2399,729,2972,1325,2956,2694,416,2730,492,1065,2637,570,510,2267,750,1697,2146,2610,362,2268,103,1144,339,451,969,99,773,204,215,75,2048,345,710,72,1419,2442,388,2407,2942,2513,2873,131,293,2049,183,1422,2924,1466,1276,136,906,938,1700,185,2807,479,70,547,410,1705,637,1569,2969,363,1708,638,381,2156,1336,1669,1863,2361,2826,480,1771,878,851,163,975,1711,271,1074,1961,174,1287,2989,1231,53,2671,562,498,326,193,1377,2363,1338,2025,82,2487,1521,2416,500,2059,2675,1580,1628,323,1675,620,3018,444,643,856,210,1116,213,2645,2831,2280,1526,2996,2646,564,309,283,1161,2367,1008,914 | 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| 3,039 |
Mitochondrial respiratory chain complex assembly | 17 | 33 | 2.945835 | 0.003221 | O96000,O75880,Q9Y6M9,P03886,Q69YU5,O43678,O95831,Q9Y276,Q9H061,O95168,Q86Y39,Q6DKK2,O75306,O43676,Q15070,Q96CU9,Q9Y2R0 | Processes and pathways | GO Biological process | msigdb_gobp | 505,474,383,38,8,445,74,144,12,232,361,338,182,62,378,61,30 | 3030,2521,62,445,1044,182,1239,474,232,2651,74,505,38,2378,1356,2135,378,1501,2307,8,338,772,361,1330,61,12,1625,1519,1520,144,30,525,383 | -3.4336046535863733,-0.6535338132122217,2.7642080742589887,0.7169170935451981,0.07114797485870293,1.6652764555563804,-0.037890347716938104,0.6565529155942527,1.3542800263786563,-0.7489239882266361,2.651981080000916,0.6160695351919047,3.275983050297943,-0.5592824068345678,-0.08191648177571846,-0.44302020696238215,0.875822884605927,-0.14840553567250234,-0.5125735357359387,4.534968841122839,0.9930928138653216,0.2849798960714869,0.9150913335574359,-0.059873687391535715,2.7801310971571085,4.058825415756852,-0.1930361462854971,-0.14840553567250234,-0.14840553567250234,1.9134596354218771,3.5439873534993933,0.5957548236023519,0.875822884605927 | 3,039 |
Glycoside hydrolase superfamily [IPR017853] | 9 | 15 | 2.944639 | 0.003233 | P06865,Q9BTY2,P10253,P04062,P16278,P54802,P07686,O60502,P06280 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 100,198,218,171,16,113,55,274,191 | 274,171,295,191,100,55,783,218,16,2192,113,2343,2004,198,1336 | 1.2040279643762803,1.7190419968762196,1.1470081486218546,1.574937930723592,2.273374172038848,2.859343234867589,0.26384394974348613,1.409965539103894,3.9467246428005365,-0.46613729363893336,2.120868736002922,-0.5358936496388635,-0.3740674450103724,1.5385430296065519,-0.059873687391535715 | 3,039 |
Phospholipid binding | 23 | 90 | 2.943716 | 0.003243 | P21796,P45880,Q13596,O60443,Q9UM22,Q92783,Q14108,Q8TEW0,P50897,O76054,P07602,O60749,Q9Y5X3,Q9NZJ7,P31749,Q8N3F8,O60313,Q15286,Q8NCC3,Q8WTV0,O14773,Q9Y4G8,P53367 | Functions | GO Molecular function | msigdb_gomf | 4,7,394,267,14,398,22,408,31,286,43,176,458,457,196,451,461,337,92,96,231,255,376 | 1119,2330,467,231,1347,2557,1433,2585,461,267,176,1588,2288,286,1780,2837,43,1980,1981,1298,2071,1537,2463,1301,1642,4,2706,701,196,2497,628,7,814,1447,2597,31,1252,376,1057,1553,650,2092,1656,394,22,993,2693,1906,1944,337,903,847,511,827,451,92,2941,408,96,2049,398,1810,1467,1111,2758,1707,639,1670,976,2322,1189,457,2847,1580,1628,1290,882,14,1291,539,945,883,1776,2233,255,1584,1161,2556,458,2763 | 0.027706804197958748,-0.5358936496388635,0.6767221488954713,1.3542800263786563,-0.08191648177571846,-0.6772732957307089,-0.12618200751855965,-0.7010844658862807,0.69684344960622,1.2229517085712236,1.7011561976657679,-0.1930361462854971,-0.5125735357359387,1.166056404831489,-0.2830431922681599,-0.9678943672344994,3.154426526604387,-0.3740674450103724,-0.3740674450103724,-0.059873687391535715,-0.4199698464474526,-0.17069011224710406,-0.606267828635831,-0.059873687391535715,-0.21544405120141735,5.053064615984644,-0.7970566811673792,0.34806687646145595,1.5385430296065519,-0.629865496214547,0.4314463011221435,4.548247176509721,0.24265397388246301,-0.12618200751855965,-0.7010844658862807,3.470285289418032,-0.037890347716938104,0.875822884605927,0.07114797485870293,-0.17069011224710406,0.4106794033765102,-0.4199698464474526,-0.21544405120141735,0.8363732981403815,3.7041893683460807,0.11436040160061789,-0.7729534155941898,-0.3284264225634382,-0.35121448743560607,0.9930928138653216,0.17875648445362774,0.22140963170165096,0.6160695351919047,0.24265397388246301,0.7169170935451981,2.373649642410284,-1.2955321839628167,0.7967405306725779,2.3236489114327066,-0.39698574608401843,0.8363732981403815,-0.2830431922681599,-0.12618200751855965,0.04945616636338176,-0.8454869482570131,-0.23791424484342957,0.4314463011221435,-0.21544405120141735,0.13588174593938243,-0.5125735357359387,0.005899515949245535,0.7169170935451981,-0.9678943672344994,-0.17069011224710406,-0.1930361462854971,-0.037890347716938104,0.20011058306743956,4.002933771034834,-0.037890347716938104,0.5753910503793658,0.15734698889488374,0.20011058306743956,-0.2604471495603937,-0.46613729363893336,1.2982381726059844,-0.17069011224710406,0.027706804197958748,-0.6535338132122217,0.7169170935451981,-0.8454869482570131 | 3,039 |
Hyperlipidemia | 9 | 28 | 2.942918 | 0.003251 | Q9UJS0,O75844,P31751,P23786,O95470,P22830,Q96AD5,P50416,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 164,73,268,108,140,15,240,245,191 | 1973,860,739,73,140,1979,191,1123,15,108,463,1891,268,2192,1933,269,676,245,1649,650,1750,999,732,1423,240,1708,164,1874 | -0.3740674450103724,0.20011058306743956,0.3060621463513644,2.668096362263561,1.9134596354218771,-0.3740674450103724,1.574937930723592,0.027706804197958748,3.9608069288536765,2.154980055528231,0.69684344960622,-0.3284264225634382,1.2229517085712236,-0.46613729363893336,-0.35121448743560607,1.2229517085712236,0.36899000714620145,1.3169587262701798,-0.21544405120141735,0.4106794033765102,-0.2604471495603937,0.11436040160061789,0.32709103081034985,-0.10401912304964674,1.3356392751731447,-0.23791424484342957,1.7902287843769074,-0.3057028045175211 | 3,039 |
SLC superfamily of solute carriers | 21 | 45 | 2.93609 | 0.003324 | Q92504,O43772,Q8WWI5,Q70HW3,Q7L0J3,Q96QD8,Q8IXU6,Q9UJS0,P53985,Q6NT16,Q9HC07,Q9H2J7,P11166,Q9NZJ7,Q8TB61,Q9UBX3,Q9H2V7,Q8NEW0,O43808,Q9H2D1,Q9Y619 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 131,129,266,137,395,270,155,164,412,172,174,442,310,457,72,77,87,345,353,120,382 | 129,353,1085,782,2704,757,783,310,759,721,2654,723,412,2784,928,529,900,3029,172,799,1855,137,395,155,345,72,266,131,875,270,775,120,442,87,456,641,174,618,457,77,164,540,382,1118,3006 | 2.0004591255918744,0.9346582601951924,0.04945616636338176,0.26384394974348613,-0.7970566811673792,0.2849798960714869,0.26384394974348613,1.0896107895774603,0.2849798960714869,0.32709103081034985,-0.7489239882266361,0.32709103081034985,0.7768548054179463,-0.8942192990435678,0.15734698889488374,0.5753910503793658,0.17875648445362774,-3.296126993909492,1.7190419968762196,0.26384394974348613,-0.3057028045175211,1.9309268460754112,0.8363732981403815,1.843249435681901,0.9736587559602312,2.6841838337725745,1.2418343865431385,2.0004591255918744,0.20011058306743956,1.2229517085712236,0.2849798960714869,2.1037649504595,0.7369433540186023,2.4233799652318058,0.7169170935451981,0.4314463011221435,1.7190419968762196,0.4521617483820871,0.7169170935451981,2.603467193814167,1.7902287843769074,0.5753910503793658,0.875822884605927,0.04945616636338176,-2.0820597615696625 | 3,039 |
Hepatomegaly | 55 | 155 | 2.930684 | 0.003382 | P16930,O96000,Q14739,O43772,O00754,Q13510,P00374,P36551,P09601,P31751,P16278,P00813,Q14108,Q01844,P33991,P20674,Q96A33,Q9UJS0,P03886,P04066,Q9NVI7,P07602,P04062,Q9Y5Y5,Q9HC07,Q96HY6,Q9UP83,O75306,P07686,Q16134,P40939,Q96CU9,P11166,O43676,P00846,P15586,Q9NZJ7,Q9BT22,Q15067,Q10713,P28070,P14174,P10253,O15118,O75880,P49748,P51798,Q9Y3E5,P23786,Q86Y39,Q96AD5,P54802,Q9Y619,P50416,Q9Y6M9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 506,505,260,129,502,6,393,520,13,268,16,20,22,528,276,32,418,164,38,295,298,43,171,304,174,439,444,182,55,313,435,61,310,62,63,187,457,195,449,197,463,80,218,93,474,228,101,518,108,361,240,113,382,245,383 | 2458,3030,2330,502,2421,93,62,129,1382,2115,1044,182,1831,598,739,1239,1197,474,2372,2066,505,2986,393,20,63,1979,38,171,295,3032,2182,1123,2119,43,55,2184,13,720,218,310,3024,3033,2686,1987,80,2374,2631,187,16,506,2033,32,2970,1246,1733,3008,108,2377,2771,463,986,2378,1891,2427,268,276,3015,743,2192,2193,520,2296,2077,1933,744,435,2131,1132,1602,795,228,2881,245,1845,1253,101,723,1313,2746,1649,113,1359,1651,1548,1494,870,528,1058,2089,197,682,1750,6,934,1498,22,2043,260,449,2046,768,313,2971,1804,2402,1807,2047,2637,361,1330,1462,2314,1765,2639,418,240,1666,61,1767,439,547,940,2577,195,616,174,618,298,2058,2549,457,1519,669,853,164,670,444,1922,2553,1676,518,2366,304,382,383 | -0.606267828635831,-3.4336046535863733,-0.5358936496388635,0.6160695351919047,-0.5827403002940941,2.35701295367094,2.7642080742589887,2.0004591255918744,-0.10401912304964674,-0.44302020696238215,0.07114797485870293,1.6652764555563804,-0.3057028045175211,0.47282605375654435,0.3060621463513644,-0.037890347716938104,-0.01596607463826186,0.6565529155942527,-0.5592824068345678,-0.4199698464474526,0.6160695351919047,-1.637897883649052,0.8363732981403815,3.890193613688759,2.7642080742589887,-0.3740674450103724,3.275983050297943,1.7190419968762196,1.1470081486218546,-3.79023183405523,-0.46613729363893336,0.027706804197958748,-0.44302020696238215,3.154426526604387,2.859343234867589,-0.46613729363893336,4.030919006514059,0.32709103081034985,1.409965539103894,1.0896107895774603,-2.803971123021496,-3.938478591705629,-0.7729534155941898,-0.3740674450103724,2.5546987479486667,-0.5592824068345678,-0.724967851906094,1.5930794075923984,3.9467246428005365,0.6160695351919047,-0.39698574608401843,3.4554772633739423,-1.477950289982449,-0.037890347716938104,-0.2604471495603937,-2.1395193234509033,2.154980055528231,-0.5592824068345678,-0.8698150771053541,0.69684344960622,0.11436040160061789,-0.5592824068345678,-0.3284264225634382,-0.5827403002940941,1.2229517085712236,1.2040279643762803,-2.403894850464115,0.3060621463513644,-0.46613729363893336,-0.46613729363893336,0.5957548236023519,-0.5125735357359387,-0.4199698464474526,-0.35121448743560607,0.3060621463513644,0.7369433540186023,-0.44302020696238215,0.027706804197958748,-0.1930361462854971,0.26384394974348613,1.3728811852532863,-1.067229155753125,1.3169587262701798,-0.3057028045175211,-0.037890347716938104,2.273374172038848,0.32709103081034985,-0.059873687391535715,-0.8454869482570131,-0.21544405120141735,2.120868736002922,-0.08191648177571846,-0.21544405120141735,-0.17069011224710406,-0.14840553567250234,0.20011058306743956,0.5753910503793658,0.07114797485870293,-0.4199698464474526,1.5385430296065519,0.36899000714620145,-0.2604471495603937,4.797294388390134,0.15734698889488374,-0.14840553567250234,3.7041893683460807,-0.39698574608401843,1.2606762141367405,0.7169170935451981,-0.39698574608401843,0.2849798960714869,1.0896107895774603,-1.477950289982449,-0.2830431922681599,-0.5592824068345678,-0.2830431922681599,-0.39698574608401843,-0.724967851906094,0.9150913335574359,-0.059873687391535715,-0.12618200751855965,-0.5125735357359387,-0.2604471495603937,-0.724967851906094,0.7768548054179463,1.3356392751731447,-0.21544405120141735,2.7801310971571085,-0.2604471495603937,0.7369433540186023,0.5549779266548395,0.15734698889488374,-0.6772732957307089,1.5567592001978614,0.4521617483820871,1.7190419968762196,0.4521617483820871,1.1470081486218546,-0.39698574608401843,-0.6535338132122217,0.7169170935451981,-0.14840553567250234,0.3898607435766084,0.22140963170165096,1.7902287843769074,0.3898607435766084,0.7369433540186023,-0.3284264225634382,-0.6535338132122217,-0.21544405120141735,0.6160695351919047,-0.5358936496388635,1.1279179444266103,0.875822884605927,0.875822884605927 | 3,039 |
Organic acid transport | 20 | 47 | 2.930351 | 0.003386 | O43772,Q7L0J3,P31751,Q9Y289,Q96QD8,Q02978,Q9UJS0,P53985,Q9H2J7,P11166,Q9H936,P31749,Q9UBX3,P14174,O43808,P08183,P23786,Q9H2D1,Q9Y619,P50416 | Processes and pathways | GO Biological process | msigdb_gobp | 129,395,268,540,270,529,164,412,442,310,456,196,77,80,353,107,108,120,382,245 | 779,1237,129,353,582,1085,542,2704,1726,2559,1780,1200,2493,107,783,310,80,1642,108,986,196,268,2429,2654,245,723,412,2784,2390,529,749,2260,900,1855,686,395,875,270,120,442,456,641,1517,77,164,540,382 | 0.26384394974348613,-0.037890347716938104,2.0004591255918744,0.9346582601951924,0.4934395229159375,0.04945616636338176,0.5549779266548395,-0.7970566811673792,-0.2604471495603937,-0.6772732957307089,-0.2830431922681599,-0.01596607463826186,-0.629865496214547,2.1719878809978588,0.26384394974348613,1.0896107895774603,2.5546987479486667,-0.21544405120141735,2.154980055528231,0.11436040160061789,1.5385430296065519,1.2229517085712236,-0.5827403002940941,-0.7489239882266361,1.3169587262701798,0.32709103081034985,0.7768548054179463,-0.8942192990435678,-0.5592824068345678,0.5753910503793658,0.3060621463513644,-0.48932157771479984,0.17875648445362774,-0.3057028045175211,0.36899000714620145,0.8363732981403815,0.20011058306743956,1.2229517085712236,2.1037649504595,0.7369433540186023,0.7169170935451981,0.4314463011221435,-0.14840553567250234,2.603467193814167,1.7902287843769074,0.5753910503793658,0.875822884605927 | 3,039 |
SLC25 family of mitochondrial transporters | 15 | 19 | 2.928531 | 0.003406 | Q9H936,P53007,O43808,Q9HC21,P05141,P12235,O43772,Q9UJS0,Q70HW3,Q9UBX3,Q9H2D1,Q9Y619,Q02978,P12236,Q9NZJ7 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 456,723,353,618,757,759,129,164,137,77,120,382,529,721,457 | 129,353,1085,757,759,721,723,928,529,799,137,120,456,618,457,77,164,382,1118 | 2.0004591255918744,0.9346582601951924,0.04945616636338176,0.2849798960714869,0.2849798960714869,0.32709103081034985,0.32709103081034985,0.15734698889488374,0.5753910503793658,0.26384394974348613,1.9309268460754112,2.1037649504595,0.7169170935451981,0.4521617483820871,0.7169170935451981,2.603467193814167,1.7902287843769074,0.875822884605927,0.04945616636338176 | 3,039 |
Mitochondrial substrate/solute carrier [IPR018108] | 15 | 19 | 2.928531 | 0.003406 | Q9H936,P53007,O43808,Q9HC21,P05141,P12235,O43772,Q9UJS0,Q70HW3,Q9UBX3,Q9H2D1,Q9Y619,Q02978,P12236,Q9NZJ7 | Sequence | InterPro Repeat | interpro_repeat | 456,723,353,618,757,759,129,164,137,77,120,382,529,721,457 | 129,353,1085,757,759,721,723,928,529,799,137,120,456,618,457,77,164,382,1118 | 2.0004591255918744,0.9346582601951924,0.04945616636338176,0.2849798960714869,0.2849798960714869,0.32709103081034985,0.32709103081034985,0.15734698889488374,0.5753910503793658,0.26384394974348613,1.9309268460754112,2.1037649504595,0.7169170935451981,0.4521617483820871,0.7169170935451981,2.603467193814167,1.7902287843769074,0.875822884605927,0.04945616636338176 | 3,039 |
Mitochondrial carrier domain superfamily [IPR023395] | 15 | 19 | 2.928531 | 0.003406 | Q9H936,P53007,O43808,Q9HC21,P05141,P12235,O43772,Q9UJS0,Q70HW3,Q9UBX3,Q9H2D1,Q9Y619,Q02978,P12236,Q9NZJ7 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 456,723,353,618,757,759,129,164,137,77,120,382,529,721,457 | 129,353,1085,757,759,721,723,928,529,799,137,120,456,618,457,77,164,382,1118 | 2.0004591255918744,0.9346582601951924,0.04945616636338176,0.2849798960714869,0.2849798960714869,0.32709103081034985,0.32709103081034985,0.15734698889488374,0.5753910503793658,0.26384394974348613,1.9309268460754112,2.1037649504595,0.7169170935451981,0.4521617483820871,0.7169170935451981,2.603467193814167,1.7902287843769074,0.875822884605927,0.04945616636338176 | 3,039 |
Cholesterol metabolism with bloch and kandutschrussell pathways | 11 | 24 | 2.922116 | 0.003477 | Q14739,Q15800,P37268,Q15125,Q15392,Q9BWD1,P48449,Q14534,Q16850,O95864,P14324 | Processes and pathways | WikiPathways | msigdb_wp | 260,264,236,10,281,179,278,148,52,243,118 | 622,1294,324,1726,243,118,2429,236,278,1602,2385,3002,1058,2658,148,260,10,1453,281,1026,264,52,179,1626 | 0.4314463011221435,-0.059873687391535715,1.0511331158891664,-0.2604471495603937,1.3169587262701798,2.1037649504595,-0.5827403002940941,1.3542800263786563,1.2040279643762803,-0.1930361462854971,-0.5592824068345678,-1.9967112632049284,0.07114797485870293,-0.7489239882266361,1.895958450657215,1.2606762141367405,4.2383322485299875,-0.12618200751855965,1.2040279643762803,0.09278259830834672,1.2418343865431385,2.9847119746833544,1.6832344093740115,-0.1930361462854971 | 3,039 |
Sterol biosynthetic process | 13 | 28 | 2.920053 | 0.0035 | Q9H2C2,Q14739,O76054,Q15800,Q6P1A2,Q15125,P37268,Q15392,P48449,Q14534,Q16850,P14324,P16435 | Processes and pathways | GO Biological process | msigdb_gobp | 163,260,286,264,200,10,236,281,278,148,52,118,184 | 286,324,887,1439,1014,118,184,236,2727,278,1254,2385,413,3002,1058,2658,148,260,10,1453,281,1026,264,52,200,163,1626,2582 | 1.166056404831489,1.0511331158891664,0.17875648445362774,-0.12618200751855965,0.09278259830834672,2.1037649504595,1.629251338660244,1.3542800263786563,-0.8212343386218275,1.2040279643762803,-0.037890347716938104,-0.5592824068345678,0.7768548054179463,-1.9967112632049284,0.07114797485870293,-0.7489239882266361,1.895958450657215,1.2606762141367405,4.2383322485299875,-0.12618200751855965,1.2040279643762803,0.09278259830834672,1.2418343865431385,2.9847119746833544,1.5202892310550606,1.7902287843769074,-0.1930361462854971,-0.6772732957307089 | 3,039 |
Intrinsic component of mitochondrial inner membrane | 23 | 30 | 2.916558 | 0.003539 | O60830,Q9Y512,Q13505,Q99595,Q53H12,Q5XKP0,Q9H9P8,Q9Y2R0,Q6P4A7,Q16134,Q9NVH1,O14925,Q9NX63,Q9HC21,O75880,Q6UXV4,Q9Y4W6,O75431,Q9H9B4,Q9BUR5,Q9UG56,Q15070,Q16891 | Localization | GO Cellular component | msigdb_gocc | 3,525,135,9,651,406,156,30,686,313,714,214,482,618,474,613,644,739,641,638,517,378,770 | 214,3,739,474,2704,2561,895,928,135,378,313,770,651,1695,406,686,613,801,875,9,638,641,156,618,714,482,517,30,644,525 | 1.4284491364966743,5.053064615984644,0.3060621463513644,0.6565529155942527,-0.7970566811673792,-0.6772732957307089,0.17875648445362774,0.15734698889488374,1.9657599830182004,0.875822884605927,1.0896107895774603,0.2849798960714869,0.4106794033765102,-0.23791424484342957,0.7967405306725779,0.36899000714620145,0.4521617483820871,0.26384394974348613,0.20011058306743956,4.495028981433672,0.4314463011221435,0.4314463011221435,1.843249435681901,0.4521617483820871,0.34806687646145595,0.6565529155942527,0.6160695351919047,3.5439873534993933,0.4314463011221435,0.5957548236023519 | 3,039 |
Parkinsons disease | 13 | 52 | 2.910454 | 0.003609 | P20674,P00403,P21796,P03886,P45880,O95168,P14406,O75306,Q9UDW1,O14949,P00846,O43676,Q9Y277 | Processes and pathways | KEGG Pathways | msigdb_kegg | 32,226,4,38,7,232,146,182,54,56,63,62,294 | 3030,915,2459,56,2521,62,445,1044,182,1239,697,232,1166,2651,505,226,63,38,757,698,1243,740,759,721,386,146,2631,841,2033,32,4,789,2426,699,289,1387,2378,2340,2379,1486,7,2562,2881,1356,1747,1941,1501,2307,2756,54,294,383 | -3.4336046535863733,0.15734698889488374,-0.606267828635831,2.843554170946297,-0.6535338132122217,2.7642080742589887,0.7169170935451981,0.07114797485870293,1.6652764555563804,-0.037890347716938104,0.34806687646145595,1.3542800263786563,0.005899515949245535,-0.7489239882266361,0.6160695351919047,1.3728811852532863,2.7642080742589887,3.275983050297943,0.2849798960714869,0.34806687646145595,-0.037890347716938104,0.3060621463513644,0.2849798960714869,0.32709103081034985,0.856120860427004,1.895958450657215,-0.724967851906094,0.22140963170165096,-0.39698574608401843,3.4554772633739423,5.053064615984644,0.26384394974348613,-0.5827403002940941,0.34806687646145595,1.166056404831489,-0.10401912304964674,-0.5592824068345678,-0.5358936496388635,-0.5592824068345678,-0.14840553567250234,4.548247176509721,-0.6772732957307089,-1.067229155753125,-0.08191648177571846,-0.2604471495603937,-0.35121448743560607,-0.14840553567250234,-0.5125735357359387,-0.8454869482570131,2.890842077222198,1.166056404831489,0.875822884605927 | 3,039 |
Neutrophil degranulation | 32 | 167 | 2.908257 | 0.003634 | Q13510,Q93050,Q9H7Z7,P16278,P10619,P30519,Q969Q5,P17900,O15260,O00584,P04066,P07602,P42785,P07686,Q92542,P15586,P06280,P09960,Q9BTY2,O00264,Q07065,O43681,P20618,P14174,Q99536,P10253,P12956,P15289,P27105,P07437,P13473,P68371 | Processes and pathways | Reactome Pathways | msigdb_reactome | 6,136,271,16,145,19,282,152,27,166,295,43,47,55,183,187,191,192,198,327,202,332,207,80,217,218,354,355,234,105,111,124 | 593,2833,327,1293,467,1194,166,502,858,2459,27,1825,838,332,1976,1588,2288,1779,1589,1833,1439,1835,295,2653,1297,1087,191,1123,1384,2837,1926,105,43,55,1478,1479,1480,2769,1298,192,2185,1440,218,864,145,1537,1386,607,787,1354,354,1683,111,1985,1299,80,1783,2987,355,187,3027,16,1015,152,2770,983,2072,2293,1641,207,984,1203,1482,234,1840,2560,19,866,1485,2192,2243,1393,1305,2129,47,1447,487,1448,2298,763,896,1995,1254,2783,630,1741,2085,368,1210,1055,1789,869,2772,2633,124,2709,1175,681,2390,2303,202,3025,1791,2347,2209,1217,1795,2304,6,1656,1556,705,1499,2729,1320,1611,707,1659,1806,846,1141,2265,2146,2610,1764,710,1183,183,453,136,282,1109,1811,2925,753,2790,2054,217,1111,733,198,2734,1863,1918,271,1231,2643,457,1338,2059,1522,1775,981,1340,1117,1342,2283 | 0.47282605375654435,-0.9678943672344994,1.0318297557529534,-0.059873687391535715,0.6767221488954713,-0.01596607463826186,1.736891982086496,0.6160695351919047,0.20011058306743956,-0.606267828635831,3.6025482837872342,-0.3057028045175211,0.22140963170165096,1.0124830674261933,-0.3740674450103724,-0.1930361462854971,-0.5125735357359387,-0.2830431922681599,-0.1930361462854971,-0.3057028045175211,-0.12618200751855965,-0.3057028045175211,1.1470081486218546,-0.7489239882266361,-0.059873687391535715,0.04945616636338176,1.574937930723592,0.027706804197958748,-0.10401912304964674,-0.9678943672344994,-0.35121448743560607,2.205908584221655,3.154426526604387,2.859343234867589,-0.14840553567250234,-0.14840553567250234,-0.14840553567250234,-0.8698150771053541,-0.059873687391535715,1.574937930723592,-0.46613729363893336,-0.12618200751855965,1.409965539103894,0.20011058306743956,1.895958450657215,-0.17069011224710406,-0.10401912304964674,0.4521617483820871,0.26384394974348613,-0.08191648177571846,0.9346582601951924,-0.23791424484342957,2.137940388935406,-0.3740674450103724,-0.059873687391535715,2.5546987479486667,-0.2830431922681599,-1.6648910028012767,0.9346582601951924,1.5930794075923984,-3.1613896324023307,3.9467246428005365,0.09278259830834672,1.8608535136088946,-0.8698150771053541,0.11436040160061789,-0.4199698464474526,-0.5125735357359387,-0.21544405120141735,1.483667990965456,0.11436040160061789,-0.01596607463826186,-0.14840553567250234,1.3542800263786563,-0.3057028045175211,-0.6772732957307089,3.9043567944213824,0.20011058306743956,-0.14840553567250234,-0.46613729363893336,-0.48932157771479984,-0.10401912304964674,-0.059873687391535715,-0.44302020696238215,3.123793940195311,-0.12618200751855965,0.6363354713395758,-0.12618200751855965,-0.5125735357359387,0.2849798960714869,0.17875648445362774,-0.3740674450103724,-0.037890347716938104,-0.8942192990435678,0.4314463011221435,-0.2604471495603937,-0.4199698464474526,0.895479624968376,-0.01596607463826186,0.07114797485870293,-0.2830431922681599,0.20011058306743956,-0.8698150771053541,-0.724967851906094,2.0694603911174667,-0.7970566811673792,0.005899515949245535,0.36899000714620145,-0.5592824068345678,-0.5125735357359387,1.5019976151465506,-2.835711100846623,-0.2830431922681599,-0.5358936496388635,-0.46613729363893336,-0.01596607463826186,-0.2830431922681599,-0.5125735357359387,4.797294388390134,-0.21544405120141735,-0.17069011224710406,0.34806687646145595,-0.14840553567250234,-0.8212343386218275,-0.059873687391535715,-0.1930361462854971,0.34806687646145595,-0.21544405120141735,-0.2830431922681599,0.22140963170165096,0.027706804197958748,-0.48932157771479984,-0.44302020696238215,-0.7010844658862807,-0.2604471495603937,0.34806687646145595,0.005899515949245535,1.6652764555563804,0.7169170935451981,1.9483602424077069,1.2040279643762803,0.04945616636338176,-0.2830431922681599,-1.1932239737205523,0.3060621463513644,-0.8942192990435678,-0.39698574608401843,1.4284491364966743,0.04945616636338176,0.32709103081034985,1.5385430296065519,-0.8212343386218275,-0.3057028045175211,-0.3284264225634382,1.2229517085712236,-0.01596607463826186,-0.724967851906094,0.7169170935451981,-0.059873687391535715,-0.39698574608401843,-0.14840553567250234,-0.2604471495603937,0.13588174593938243,-0.059873687391535715,0.04945616636338176,-0.059873687391535715,-0.48932157771479984 | 3,039 |
FAD/NAD(P)-binding domain superfamily [IPR036188] | 7 | 19 | 2.90716 | 0.003647 | Q6NUM9,O95831,Q14534,Q16134,Q9H9P8,Q96CU9,Q9UHG3 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 258,74,148,313,156,61,29 | 1042,74,1534,720,2125,2340,1390,793,895,1448,148,313,2397,258,663,340,61,156,29 | 0.07114797485870293,2.651981080000916,-0.17069011224710406,0.32709103081034985,-0.44302020696238215,-0.5358936496388635,-0.10401912304964674,0.26384394974348613,0.17875648445362774,-0.12618200751855965,1.895958450657215,1.0896107895774603,-0.5592824068345678,1.2794774054002804,0.3898607435766084,0.9930928138653216,2.7801310971571085,1.843249435681901,3.5879411184001437 | 3,039 |
Intracellular protein transmembrane transport | 11 | 22 | 2.902019 | 0.003708 | Q99442,O60830,Q99595,O95831,P31751,Q9Y5Y5,O43615,Q15388,Q15629,O75298,O14925 | Processes and pathways | GO Biological process | msigdb_gobp | 454,3,9,74,268,304,460,114,211,151,214 | 214,460,3,151,598,2178,74,862,2684,268,2251,1651,2252,114,211,1503,511,454,9,1672,853,304 | 1.4284491364966743,0.69684344960622,5.053064615984644,1.8608535136088946,0.47282605375654435,-0.46613729363893336,2.651981080000916,0.20011058306743956,-0.7729534155941898,1.2229517085712236,-0.48932157771479984,-0.21544405120141735,-0.48932157771479984,2.120868736002922,1.4653001660607239,-0.14840553567250234,0.6160695351919047,0.7169170935451981,4.495028981433672,-0.21544405120141735,0.22140963170165096,1.1279179444266103 | 3,039 |
Abnormality of the biliary system | 30 | 100 | 2.90123 | 0.003717 | Q14739,Q9Y4P3,Q13510,Q8WWI5,P00374,Q9Y276,P09601,P22830,Q14108,Q5XKP0,Q96A33,Q9UJS0,P04066,P55263,Q9NSD9,P07602,P04062,Q9Y5Y5,Q16134,P40939,P11166,P21964,Q10713,O43681,P14174,O15118,P15289,P49748,Q96AD5,Q9Y3Z3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,261,6,266,393,144,13,15,22,406,418,164,295,296,432,43,171,304,313,435,310,317,197,332,80,93,355,228,240,248 | 2938,1631,2648,738,93,332,598,782,2986,1168,393,1979,171,295,2653,1198,1123,1384,43,2183,1781,13,840,310,2463,1014,2686,1987,80,355,2687,2337,2970,317,15,986,1737,2193,520,1786,1393,2077,1933,744,435,2744,1091,1132,228,1845,1253,926,1996,2746,1649,2133,296,1491,2935,2205,870,2135,1057,2257,197,682,2393,6,22,260,1322,768,313,1804,406,2402,1807,2314,266,2481,1562,2446,418,240,940,851,2898,1711,432,457,1626,2699,164,670,2675,144,248,261,737,304 | -1.2955321839628167,-0.21544405120141735,-0.7489239882266361,0.3060621463513644,2.35701295367094,1.0124830674261933,0.47282605375654435,0.26384394974348613,-1.637897883649052,0.005899515949245535,0.8363732981403815,-0.3740674450103724,1.7190419968762196,1.1470081486218546,-0.7489239882266361,-0.01596607463826186,0.027706804197958748,-0.10401912304964674,3.154426526604387,-0.46613729363893336,-0.2830431922681599,4.030919006514059,0.22140963170165096,1.0896107895774603,-0.606267828635831,0.09278259830834672,-0.7729534155941898,-0.3740674450103724,2.5546987479486667,0.9346582601951924,-0.7729534155941898,-0.5358936496388635,-1.477950289982449,1.070393382836239,3.9608069288536765,0.11436040160061789,-0.2604471495603937,-0.46613729363893336,0.5957548236023519,-0.2830431922681599,-0.10401912304964674,-0.4199698464474526,-0.35121448743560607,0.3060621463513644,0.7369433540186023,-0.8454869482570131,0.04945616636338176,0.027706804197958748,1.3728811852532863,-0.3057028045175211,-0.037890347716938104,0.15734698889488374,-0.3740674450103724,-0.8454869482570131,-0.21544405120141735,-0.44302020696238215,1.1470081486218546,-0.14840553567250234,-1.2698263697676262,-0.46613729363893336,0.20011058306743956,-0.44302020696238215,0.07114797485870293,-0.48932157771479984,1.5385430296065519,0.36899000714620145,-0.5592824068345678,4.797294388390134,3.7041893683460807,1.2606762141367405,-0.059873687391535715,0.2849798960714869,1.0896107895774603,-0.2830431922681599,0.7967405306725779,-0.5592824068345678,-0.2830431922681599,-0.5125735357359387,1.2418343865431385,-0.606267828635831,-0.17069011224710406,-0.5827403002940941,0.7768548054179463,1.3356392751731447,0.15734698889488374,0.22140963170165096,-1.0922636419622016,-0.23791424484342957,0.7569225018513692,0.7169170935451981,-0.1930361462854971,-0.7729534155941898,1.7902287843769074,0.3898607435766084,-0.7489239882266361,1.9134596354218771,1.3169587262701798,1.2606762141367405,0.32709103081034985,1.1279179444266103 | 3,039 |
Organelle membrane contact site | 9 | 17 | 2.894577 | 0.003797 | Q96N66,Q9Y320,O43865,O95772,Q15388,Q5XKP0,Q14849,Q96S66,P51572 | Localization | GO Cellular component | msigdb_gocc | 186,466,333,110,114,406,25,410,251 | 1119,333,1294,110,862,890,251,25,114,406,1183,186,410,973,2317,498,466 | 0.027706804197958748,1.0124830674261933,-0.059873687391535715,2.137940388935406,0.20011058306743956,0.17875648445362774,1.2982381726059844,3.646238633225624,2.120868736002922,0.7967405306725779,0.005899515949245535,1.629251338660244,0.7967405306725779,0.13588174593938243,-0.5125735357359387,0.6363354713395758,0.69684344960622 | 3,039 |
Glycosidase | 9 | 15 | 2.890728 | 0.003844 | P06865,Q9BTY2,P10253,P04062,P16278,P54802,P07686,O60502,P06280 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 100,198,218,171,16,113,55,274,191 | 502,695,274,171,295,191,100,55,218,16,2192,113,1498,2004,198 | 0.6160695351919047,0.34806687646145595,1.2040279643762803,1.7190419968762196,1.1470081486218546,1.574937930723592,2.273374172038848,2.859343234867589,1.409965539103894,3.9467246428005365,-0.46613729363893336,2.120868736002922,-0.14840553567250234,-0.3740674450103724,1.5385430296065519 | 3,039 |
Vascular skin abnormality | 28 | 106 | 2.876506 | 0.004021 | Q14739,P38435,Q15125,P49257,P22830,P16278,P10619,Q14108,Q8NC56,P03886,P04066,P04062,Q9BXW9,O75306,P21964,P06280,P00846,P31749,O75844,Q8NCH0,Q8IZA0,P53701,P00403,P51798,Q13126,P51648,Q9NWM8,Q9Y3Z3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,263,10,269,15,16,145,22,292,38,295,171,308,182,317,191,63,196,73,75,339,343,226,101,229,104,242,248 | 1120,2648,1973,2522,1382,2115,1436,182,73,1725,2066,226,63,1979,38,171,295,191,2119,2526,145,840,1353,2686,3027,16,1731,1887,2796,2878,1642,789,317,3008,15,2771,1891,1304,196,1542,743,1249,2632,2296,263,2194,1739,2195,269,1602,2198,104,101,1174,343,1996,1788,1491,2254,2255,1058,349,2208,555,477,682,229,3010,1750,2473,22,2882,2504,260,2693,10,1800,1755,1026,2940,1757,2822,799,1855,1140,339,292,75,1421,1562,1423,2639,1226,1111,308,2617,1816,242,2549,1626,2676,1525,1676,248,420,737 | 0.027706804197958748,-0.7489239882266361,-0.3740674450103724,-0.6535338132122217,-0.10401912304964674,-0.44302020696238215,-0.12618200751855965,1.6652764555563804,2.668096362263561,-0.2604471495603937,-0.4199698464474526,1.3728811852532863,2.7642080742589887,-0.3740674450103724,3.275983050297943,1.7190419968762196,1.1470081486218546,1.574937930723592,-0.44302020696238215,-0.6535338132122217,1.895958450657215,0.22140963170165096,-0.08191648177571846,-0.7729534155941898,-3.1613896324023307,3.9467246428005365,-0.2604471495603937,-0.3284264225634382,-0.9187001949064155,-1.067229155753125,-0.21544405120141735,0.26384394974348613,1.070393382836239,-2.1395193234509033,3.9608069288536765,-0.8698150771053541,-0.3284264225634382,-0.059873687391535715,1.5385430296065519,-0.17069011224710406,0.3060621463513644,-0.037890347716938104,-0.724967851906094,-0.5125735357359387,1.2418343865431385,-0.46613729363893336,-0.2604471495603937,-0.46613729363893336,1.2229517085712236,-0.1930361462854971,-0.46613729363893336,2.2397036396343815,2.273374172038848,0.005899515949245535,0.9736587559602312,-0.3740674450103724,-0.2830431922681599,-0.14840553567250234,-0.48932157771479984,-0.48932157771479984,0.07114797485870293,0.9541806525094901,-0.46613729363893336,0.5345151608497005,0.6565529155942527,0.36899000714620145,1.3728811852532863,-2.1684205196784307,-0.2604471495603937,-0.606267828635831,3.7041893683460807,-1.067229155753125,-0.629865496214547,1.2606762141367405,-0.7729534155941898,4.2383322485299875,-0.2830431922681599,-0.2604471495603937,0.09278259830834672,-1.2955321839628167,-0.2604471495603937,-0.9432583526028255,0.26384394974348613,-0.3057028045175211,0.027706804197958748,0.9930928138653216,1.166056404831489,2.651981080000916,-0.10401912304964674,-0.17069011224710406,-0.10401912304964674,-0.724967851906094,-0.01596607463826186,0.04945616636338176,1.1087855671016753,-0.7010844658862807,-0.2830431922681599,1.3356392751731447,-0.6535338132122217,-0.1930361462854971,-0.7489239882266361,-0.14840553567250234,-0.21544405120141735,1.3169587262701798,0.7768548054179463,0.32709103081034985 | 3,039 |
Cellular lipid metabolic process | 76 | 203 | 2.873499 | 0.00406 | Q6NUM9,Q9UBV2,Q13510,Q8WWI5,Q16739,Q15800,Q8NHP8,P31751,O95470,P16278,Q9H7Z7,A1L0T0,P48449,Q8N2K0,P17900,Q8N4Q0,P50897,P27544,Q9H2C2,P07099,P54646,P04066,Q9BY49,P07602,Q96G23,P04062,Q13011,Q86YN1,Q53GQ0,Q9BWD1,Q14914,Q9P035,O00116,Q16134,P07686,P16435,Q96N66,P40939,Q8N5B7,P06280,Q9NZJ7,Q9NX62,Q9BT22,P31749,Q10713,Q9HB40,Q15067,O75844,Q6P1A2,P14174,P35790,Q8NBX0,O15254,P34913,Q8NCC3,Q9C0D9,Q06136,O15269,Q96F25,Q8WTV0,O43808,P06865,P49748,Q9BTU6,P51648,P37268,Q9NTJ5,Q9NPH0,P23786,Q9UG56,Q96AD5,Q8IXJ6,P14324,P50416,O95864,Q8TBX8 | Processes and pathways | GO Biological process | msigdb_gobp | 258,391,6,266,265,264,11,268,140,16,271,400,278,407,152,158,31,161,163,37,413,295,431,43,44,171,46,302,427,179,177,443,181,313,55,184,186,435,452,191,457,193,195,196,197,71,449,73,200,80,83,84,85,468,92,480,349,347,379,96,353,100,228,363,104,236,498,497,108,517,240,247,118,245,243,126 | 400,2963,181,1162,2330,656,3035,622,779,1039,2909,837,85,347,595,1433,353,1294,1476,1382,1831,2768,1636,1723,73,1779,887,1048,140,1726,2849,243,3028,171,295,1780,3032,2182,191,100,37,1242,43,55,2769,3024,2630,1987,80,118,1538,3031,16,184,2852,152,2965,2706,646,108,2377,2467,161,986,2560,2861,843,196,268,2429,468,83,236,2077,435,1394,1688,2727,1250,2246,278,2195,1602,228,245,31,104,1253,1254,2385,1095,413,2133,2817,2390,3002,1552,1058,349,545,555,2912,197,46,3036,3010,6,2658,177,449,612,1453,2801,264,313,707,265,685,1414,1220,822,427,651,1415,846,533,258,200,1855,1222,2477,302,247,1505,407,158,452,904,937,84,92,664,2754,710,11,126,731,96,1223,829,266,1331,1333,1765,1423,240,1184,2929,379,44,186,876,2577,2317,1335,2668,655,195,363,1571,1623,3038,179,1515,431,639,480,163,271,1625,71,515,1517,497,1962,498,2947,193,1377,578,457,443,1338,1521,391,517,2416,2329,1290,537,694,1160,2368 | 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| 3,039 |
Abnormal biliary tract morphology | 12 | 23 | 2.871414 | 0.004086 | P15289,Q14739,Q10713,Q9NSD9,Q9Y276,P07602,P09601,P04062,O43681,P14174,Q5XKP0,Q14108 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 355,260,197,432,144,43,13,171,332,80,406,22 | 332,1979,171,43,13,80,355,2970,1786,1132,1253,2746,197,682,22,260,406,2446,432,457,670,144,737 | 1.0124830674261933,-0.3740674450103724,1.7190419968762196,3.154426526604387,4.030919006514059,2.5546987479486667,0.9346582601951924,-1.477950289982449,-0.2830431922681599,0.027706804197958748,-0.037890347716938104,-0.8454869482570131,1.5385430296065519,0.36899000714620145,3.7041893683460807,1.2606762141367405,0.7967405306725779,-0.5827403002940941,0.7569225018513692,0.7169170935451981,0.3898607435766084,1.9134596354218771,0.32709103081034985 | 3,039 |
Sterol binding | 6 | 15 | 2.867583 | 0.004136 | P21796,P45880,O95772,Q14108,Q14849,O15118 | Functions | GO Molecular function | msigdb_gomf | 4,7,110,22,25,93 | 93,887,110,1981,4,2706,646,235,7,22,25,1705,1669,639,776 | 2.35701295367094,0.17875648445362774,2.137940388935406,-0.3740674450103724,5.053064615984644,-0.7970566811673792,0.4106794033765102,1.3542800263786563,4.548247176509721,3.7041893683460807,3.646238633225624,-0.23791424484342957,-0.21544405120141735,0.4314463011221435,0.2849798960714869 | 3,039 |
primary active transporter | 7 | 20 | 2.85493 | 0.004305 | Q92504,Q9NS69,P16615,P05023,O60888,Q15388,Q8N4H5 | Functions | Panther Protein class | panther_protein_class | 131,5,233,334,139,114,58 | 139,598,2178,862,334,1441,233,760,959,114,900,686,58,131,875,850,442,641,1672,5 | 1.9134596354218771,0.47282605375654435,-0.46613729363893336,0.20011058306743956,1.0124830674261933,-0.12618200751855965,1.3542800263786563,0.2849798960714869,0.13588174593938243,2.120868736002922,0.17875648445362774,0.36899000714620145,2.843554170946297,2.0004591255918744,0.20011058306743956,0.22140963170165096,0.7369433540186023,0.4314463011221435,-0.21544405120141735,4.964265885140395 | 3,039 |
Regulation of hormone levels | 18 | 56 | 2.846751 | 0.004417 | Q6NUM9,Q8N5M9,P42892,P53985,Q9HB40,Q06520,O75844,P30536,Q53GQ0,P05023,O95470,P51809,Q96AD5,P50416,Q14849,P40939,P16435,P14735 | Processes and pathways | GO Biological process | msigdb_gobp | 258,344,68,412,71,88,73,235,427,334,140,367,240,245,25,435,184,249 | 1719,2910,1041,1294,1476,73,140,2704,920,1780,334,1781,249,1538,184,1015,2706,235,1541,435,68,2655,245,1253,367,412,680,88,797,820,1059,471,25,685,1414,427,258,2967,2611,1330,344,937,848,801,731,240,2665,1334,2756,2668,1571,71,1626,1582,945,1160 | -0.2604471495603937,-1.142578020067442,0.07114797485870293,-0.059873687391535715,-0.14840553567250234,2.668096362263561,1.9134596354218771,-0.7970566811673792,0.15734698889488374,-0.2830431922681599,1.0124830674261933,-0.2830431922681599,1.2982381726059844,-0.17069011224710406,1.629251338660244,0.09278259830834672,-0.7970566811673792,1.3542800263786563,-0.17069011224710406,0.7369433540186023,2.716275809025029,-0.7489239882266361,1.3169587262701798,-0.037890347716938104,0.895479624968376,0.7768548054179463,0.36899000714620145,2.4068330171621493,0.26384394974348613,0.24265397388246301,0.07114797485870293,0.6767221488954713,3.646238633225624,0.36899000714620145,-0.10401912304964674,0.7569225018513692,1.2794774054002804,-1.451619920580497,-0.7010844658862807,-0.059873687391535715,0.9736587559602312,0.15734698889488374,0.22140963170165096,0.26384394974348613,0.32709103081034985,1.3356392751731447,-0.7489239882266361,-0.059873687391535715,-0.8454869482570131,-0.7489239882266361,-0.17069011224710406,2.7002436108444896,-0.1930361462854971,-0.17069011224710406,0.15734698889488374,0.027706804197958748 | 3,039 |
Tetrapyrrole binding | 9 | 16 | 2.844011 | 0.004455 | O43169,O00264,P09601,Q9H7Z7,P30519,Q16850,O15173,P53701,Q8WUJ1 | Functions | GO Molecular function | msigdb_gomf | 35,327,13,271,19,52,51,343,159 | 327,51,35,1243,13,1733,19,343,52,371,159,1767,1001,271,2989,1078 | 1.0318297557529534,3.0002666726045604,3.3211717072673803,-0.037890347716938104,4.030919006514059,-0.2604471495603937,3.9043567944213824,0.9736587559602312,2.9847119746833544,0.895479624968376,1.8256107323317246,-0.2604471495603937,0.11436040160061789,1.2229517085712236,-1.719172153536557,0.07114797485870293 | 3,039 |
Liposaccharide metabolic process | 8 | 14 | 2.840075 | 0.00451 | P06865,Q16739,P04062,P16278,Q8NBX0,P07686,P17900,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 100,265,171,16,84,55,152,191 | 1433,1382,171,295,191,100,55,16,152,545,265,84,1423,2577 | -0.12618200751855965,-0.10401912304964674,1.7190419968762196,1.1470081486218546,1.574937930723592,2.273374172038848,2.859343234867589,3.9467246428005365,1.8608535136088946,0.5549779266548395,1.2418343865431385,2.5383854672922426,-0.10401912304964674,-0.6772732957307089 | 3,039 |
Cellular hormone metabolic process | 6 | 17 | 2.837278 | 0.00455 | P42892,Q9HB40,P30536,O95470,Q96AD5,Q14849 | Processes and pathways | GO Biological process | msigdb_gobp | 68,71,235,140,240,25 | 1476,140,1538,235,68,1253,25,427,258,937,848,731,240,2668,1571,71,1160 | -0.14840553567250234,1.9134596354218771,-0.17069011224710406,1.3542800263786563,2.716275809025029,-0.037890347716938104,3.646238633225624,0.7569225018513692,1.2794774054002804,0.15734698889488374,0.22140963170165096,0.32709103081034985,1.3356392751731447,-0.7489239882266361,-0.17069011224710406,2.7002436108444896,0.027706804197958748 | 3,039 |
FDA approved drug targets | 32 | 119 | 2.836359 | 0.004563 | P49721,Q16739,P38435,P00374,Q7L0J3,Q96QD8,P49356,P00813,Q14534,Q14145,P03886,Q8N0U8,Q16850,Q16134,P21964,P05023,P20618,Q7LG56,P10253,P50416,Q99720,Q13423,P07437,P16615,P23786,P27361,P14324,O95864,P05091,P68371,P28074,P14735 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 130,265,263,393,395,270,401,20,148,279,38,41,52,313,317,334,207,212,218,245,97,102,105,233,108,237,118,243,117,124,374,249 | 858,2175,755,2116,597,1779,243,1050,393,1534,1835,1592,20,1383,38,1780,475,2068,1729,334,117,757,1200,2525,2837,105,2070,2769,2071,1536,2526,218,1983,2876,626,759,721,1354,1984,2814,921,1985,118,249,1538,233,760,207,583,984,1246,1888,317,1733,2464,2294,108,2879,2075,237,2901,374,1929,1991,2861,2428,2340,791,1842,1600,955,263,1205,2707,792,1994,794,1602,488,401,130,2384,245,1254,1095,413,2784,554,124,2389,1607,2819,2254,2391,2208,102,2304,1942,279,148,2004,900,313,1180,265,1414,52,2397,395,212,41,2015,270,1001,2668,97,1429,473,883 | 0.20011058306743956,-0.46613729363893336,0.2849798960714869,-0.44302020696238215,0.47282605375654435,-0.2830431922681599,1.3169587262701798,0.07114797485870293,0.8363732981403815,-0.17069011224710406,-0.3057028045175211,-0.1930361462854971,3.890193613688759,-0.10401912304964674,3.275983050297943,-0.2830431922681599,0.6565529155942527,-0.4199698464474526,-0.2604471495603937,1.0124830674261933,2.1037649504595,0.2849798960714869,-0.01596607463826186,-0.6535338132122217,-0.9678943672344994,2.205908584221655,-0.4199698464474526,-0.8698150771053541,-0.4199698464474526,-0.17069011224710406,-0.6535338132122217,1.409965539103894,-0.3740674450103724,-1.067229155753125,0.4314463011221435,0.2849798960714869,0.32709103081034985,-0.08191648177571846,-0.3740674450103724,-0.9432583526028255,0.15734698889488374,-0.3740674450103724,2.1037649504595,1.2982381726059844,-0.17069011224710406,1.3542800263786563,0.2849798960714869,1.483667990965456,0.4934395229159375,0.11436040160061789,-0.037890347716938104,-0.3284264225634382,1.070393382836239,-0.2604471495603937,-0.606267828635831,-0.5125735357359387,2.154980055528231,-1.067229155753125,-0.4199698464474526,1.3356392751731447,-1.1173797137356305,0.875822884605927,-0.35121448743560607,-0.3740674450103724,-1.0174023844038849,-0.5827403002940941,-0.5358936496388635,0.26384394974348613,-0.3057028045175211,-0.1930361462854971,0.13588174593938243,1.2418343865431385,-0.01596607463826186,-0.7970566811673792,0.26384394974348613,-0.3740674450103724,0.26384394974348613,-0.1930361462854971,0.6363354713395758,0.8165799411791222,2.0004591255918744,-0.5592824068345678,1.3169587262701798,-0.037890347716938104,0.04945616636338176,0.7768548054179463,-0.8942192990435678,0.5345151608497005,2.0694603911174667,-0.5592824068345678,-0.1930361462854971,-0.9432583526028255,-0.48932157771479984,-0.5592824068345678,-0.46613729363893336,2.273374172038848,-0.5125735357359387,-0.35121448743560607,1.2040279643762803,1.895958450657215,-0.3740674450103724,0.17875648445362774,1.0896107895774603,0.005899515949245535,1.2418343865431385,-0.10401912304964674,2.9847119746833544,-0.5592824068345678,0.8363732981403815,1.4653001660607239,3.230580299955269,-0.3740674450103724,1.2229517085712236,0.11436040160061789,-0.7489239882266361,2.3236489114327066,-0.10401912304964674,0.6767221488954713,0.20011058306743956 | 3,039 |
FDA approved drug targets | 32 | 119 | 2.836359 | 0.004563 | P49721,Q16739,P38435,P00374,Q7L0J3,Q96QD8,P49356,P00813,Q14534,Q14145,P03886,Q8N0U8,Q16850,Q16134,P21964,P05023,P20618,Q7LG56,P10253,P50416,Q99720,Q13423,P07437,P16615,P23786,P27361,P14324,O95864,P05091,P68371,P28074,P14735 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 130,265,263,393,395,270,401,20,148,279,38,41,52,313,317,334,207,212,218,245,97,102,105,233,108,237,118,243,117,124,374,249 | 858,2175,755,2116,597,1779,243,1050,393,1534,1835,1592,20,1383,38,1780,475,2068,1729,334,117,757,1200,2525,2837,105,2070,2769,2071,1536,2526,218,1983,2876,626,759,721,1354,1984,2814,921,1985,118,249,1538,233,760,207,583,984,1246,1888,317,1733,2464,2294,108,2879,2075,237,2901,374,1929,1991,2861,2428,2340,791,1842,1600,955,263,1205,2707,792,1994,794,1602,488,401,130,2384,245,1254,1095,413,2784,554,124,2389,1607,2819,2254,2391,2208,102,2304,1942,279,148,2004,900,313,1180,265,1414,52,2397,395,212,41,2015,270,1001,2668,97,1429,473,883 | 0.20011058306743956,-0.46613729363893336,0.2849798960714869,-0.44302020696238215,0.47282605375654435,-0.2830431922681599,1.3169587262701798,0.07114797485870293,0.8363732981403815,-0.17069011224710406,-0.3057028045175211,-0.1930361462854971,3.890193613688759,-0.10401912304964674,3.275983050297943,-0.2830431922681599,0.6565529155942527,-0.4199698464474526,-0.2604471495603937,1.0124830674261933,2.1037649504595,0.2849798960714869,-0.01596607463826186,-0.6535338132122217,-0.9678943672344994,2.205908584221655,-0.4199698464474526,-0.8698150771053541,-0.4199698464474526,-0.17069011224710406,-0.6535338132122217,1.409965539103894,-0.3740674450103724,-1.067229155753125,0.4314463011221435,0.2849798960714869,0.32709103081034985,-0.08191648177571846,-0.3740674450103724,-0.9432583526028255,0.15734698889488374,-0.3740674450103724,2.1037649504595,1.2982381726059844,-0.17069011224710406,1.3542800263786563,0.2849798960714869,1.483667990965456,0.4934395229159375,0.11436040160061789,-0.037890347716938104,-0.3284264225634382,1.070393382836239,-0.2604471495603937,-0.606267828635831,-0.5125735357359387,2.154980055528231,-1.067229155753125,-0.4199698464474526,1.3356392751731447,-1.1173797137356305,0.875822884605927,-0.35121448743560607,-0.3740674450103724,-1.0174023844038849,-0.5827403002940941,-0.5358936496388635,0.26384394974348613,-0.3057028045175211,-0.1930361462854971,0.13588174593938243,1.2418343865431385,-0.01596607463826186,-0.7970566811673792,0.26384394974348613,-0.3740674450103724,0.26384394974348613,-0.1930361462854971,0.6363354713395758,0.8165799411791222,2.0004591255918744,-0.5592824068345678,1.3169587262701798,-0.037890347716938104,0.04945616636338176,0.7768548054179463,-0.8942192990435678,0.5345151608497005,2.0694603911174667,-0.5592824068345678,-0.1930361462854971,-0.9432583526028255,-0.48932157771479984,-0.5592824068345678,-0.46613729363893336,2.273374172038848,-0.5125735357359387,-0.35121448743560607,1.2040279643762803,1.895958450657215,-0.3740674450103724,0.17875648445362774,1.0896107895774603,0.005899515949245535,1.2418343865431385,-0.10401912304964674,2.9847119746833544,-0.5592824068345678,0.8363732981403815,1.4653001660607239,3.230580299955269,-0.3740674450103724,1.2229517085712236,0.11436040160061789,-0.7489239882266361,2.3236489114327066,-0.10401912304964674,0.6767221488954713,0.20011058306743956 | 3,039 |
Coated vesicle | 18 | 84 | 2.831386 | 0.004635 | Q5VW38,Q15363,P24390,P42892,O95070,P49755,P49257,O00165,P51809,Q8N511,Q15286,Q9Y282,Q14108,Q9Y3B3,O75396,Q9BVK6,Q9P253,P51572 | Localization | GO Cellular component | msigdb_gocc | 95,65,1,68,287,387,269,331,367,50,337,213,22,309,275,381,352,251 | 331,2458,2330,859,1346,1082,1163,2628,541,1881,1831,275,1589,2740,287,1167,1637,1727,1383,1087,863,864,2684,1537,787,405,583,1,1392,68,1207,269,387,925,1935,251,367,2783,2250,630,815,1996,1054,1055,1097,1746,2136,1552,1748,765,1609,2092,22,993,337,65,1136,95,2399,50,938,1666,1564,381,1863,851,640,1287,562,642,352,2487,1578,2059,1580,1675,213,564,309,1161,2367,1008,2763,914 | 1.0124830674261933,-0.606267828635831,-0.5358936496388635,0.20011058306743956,-0.08191648177571846,0.04945616636338176,0.005899515949245535,-0.724967851906094,0.5549779266548395,-0.3284264225634382,-0.3057028045175211,1.2040279643762803,-0.1930361462854971,-0.8454869482570131,1.166056404831489,0.005899515949245535,-0.21544405120141735,-0.2604471495603937,-0.10401912304964674,0.04945616636338176,0.20011058306743956,0.20011058306743956,-0.7729534155941898,-0.17069011224710406,0.26384394974348613,0.7967405306725779,0.4934395229159375,5.339593503895038,-0.10401912304964674,2.716275809025029,-0.01596607463826186,1.2229517085712236,0.856120860427004,0.15734698889488374,-0.35121448743560607,1.2982381726059844,0.895479624968376,-0.8942192990435678,-0.48932157771479984,0.4314463011221435,0.24265397388246301,-0.3740674450103724,0.07114797485870293,0.07114797485870293,0.04945616636338176,-0.2604471495603937,-0.44302020696238215,-0.17069011224710406,-0.2604471495603937,0.2849798960714869,-0.1930361462854971,-0.4199698464474526,3.7041893683460807,0.11436040160061789,0.9930928138653216,2.748257927082434,0.027706804197958748,2.3236489114327066,-0.5592824068345678,3.0312996064863214,0.15734698889488374,-0.21544405120141735,-0.17069011224710406,0.875822884605927,-0.3057028045175211,0.22140963170165096,0.4314463011221435,-0.037890347716938104,0.5345151608497005,0.4314463011221435,0.9541806525094901,-0.606267828635831,-0.17069011224710406,-0.39698574608401843,-0.17069011224710406,-0.21544405120141735,1.446893946428851,0.5345151608497005,1.1087855671016753,0.027706804197958748,-0.5358936496388635,0.11436040160061789,-0.8454869482570131,0.17875648445362774 | 3,039 |
Abnormal circulating cholesterol concentration | 10 | 29 | 2.824428 | 0.004737 | Q9UJS0,Q14739,Q15800,P37268,Q15125,Q9NVI7,P07602,Q15392,Q8N511,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 164,260,264,236,10,298,43,281,50,457 | 739,1979,1123,43,468,236,1933,2080,600,676,1845,1257,1552,1365,650,260,10,281,1026,264,768,50,999,1708,298,457,1626,164,1008 | 0.3060621463513644,-0.3740674450103724,0.027706804197958748,3.154426526604387,0.6767221488954713,1.3542800263786563,-0.35121448743560607,-0.4199698464474526,0.47282605375654435,0.36899000714620145,-0.3057028045175211,-0.037890347716938104,-0.17069011224710406,-0.08191648177571846,0.4106794033765102,1.2606762141367405,4.2383322485299875,1.2040279643762803,0.09278259830834672,1.2418343865431385,0.2849798960714869,3.0312996064863214,0.11436040160061789,-0.23791424484342957,1.1470081486218546,0.7169170935451981,-0.1930361462854971,1.7902287843769074,0.11436040160061789 | 3,039 |
Proton transmembrane transport | 12 | 41 | 2.823155 | 0.004755 | P20674,P00403,P24539,O75964,P13073,Q13423,P05023,Q7KZN9,Q9UDW1,Q96ES6,P51790,P00846 | Processes and pathways | GO Biological process | msigdb_gobp | 32,226,289,134,386,102,334,371,54,346,219,63 | 915,1237,860,1044,697,134,226,63,334,757,698,1243,740,759,386,32,1246,1888,289,1387,2428,2379,1486,2632,2194,2562,219,602,816,844,928,102,371,346,2756,1335,456,54,2416,1190,1290 | 0.15734698889488374,-0.037890347716938104,0.20011058306743956,0.07114797485870293,0.34806687646145595,1.9657599830182004,1.3728811852532863,2.7642080742589887,1.0124830674261933,0.2849798960714869,0.34806687646145595,-0.037890347716938104,0.3060621463513644,0.2849798960714869,0.856120860427004,3.4554772633739423,-0.037890347716938104,-0.3284264225634382,1.166056404831489,-0.10401912304964674,-0.5827403002940941,-0.5592824068345678,-0.14840553567250234,-0.724967851906094,-0.46613729363893336,-0.6772732957307089,1.409965539103894,0.47282605375654435,0.24265397388246301,0.22140963170165096,0.15734698889488374,2.273374172038848,0.895479624968376,0.9736587559602312,-0.8454869482570131,-0.059873687391535715,0.7169170935451981,2.890842077222198,-0.5592824068345678,0.005899515949245535,-0.037890347716938104 | 3,039 |
Establishment of protein localization to membrane | 29 | 84 | 2.810002 | 0.004954 | Q9Y5J9,Q9NS69,Q9Y512,Q9Y276,P31751,P46379,Q8TEW0,P43307,Q07812,Q96A33,Q4J6C6,Q9UHB9,Q5J8M3,Q9Y5Y5,Q9NQG6,O14737,Q8WWC4,Q9HD20,Q99442,Q8N3F8,O43681,O60725,Q15629,O00560,O15118,Q8N4V1,P27105,Q15070,Q86YS7 | Processes and pathways | GO Biological process | msigdb_gobp | 392,5,525,144,268,23,408,28,545,418,414,563,556,304,175,305,572,66,454,451,332,76,211,467,93,99,234,378,511 | 2832,2458,467,305,1082,93,1633,332,565,76,1723,1437,2178,1726,1479,2741,234,2339,1390,268,1892,1305,744,1843,28,23,2430,893,896,1255,2251,1054,1651,1210,2252,2432,745,1057,545,632,2475,766,749,2260,378,211,768,414,2605,651,556,3007,511,1144,451,99,2010,1031,408,572,418,1148,454,2361,2932,1074,942,66,1287,175,5,2323,1520,853,563,2416,1580,1628,643,144,2170,525,392,304 | -0.9678943672344994,-0.606267828635831,0.6767221488954713,1.1087855671016753,0.04945616636338176,2.35701295367094,-0.21544405120141735,1.0124830674261933,0.5140024586389151,2.603467193814167,-0.2604471495603937,-0.12618200751855965,-0.46613729363893336,-0.2604471495603937,-0.14840553567250234,-0.8454869482570131,1.3542800263786563,-0.5358936496388635,-0.10401912304964674,1.2229517085712236,-0.3284264225634382,-0.059873687391535715,0.3060621463513644,-0.3057028045175211,3.5879411184001437,3.675257034989104,-0.5827403002940941,0.17875648445362774,0.17875648445362774,-0.037890347716938104,-0.48932157771479984,0.07114797485870293,-0.21544405120141735,-0.01596607463826186,-0.48932157771479984,-0.5827403002940941,0.3060621463513644,0.07114797485870293,0.5549779266548395,0.4314463011221435,-0.606267828635831,0.2849798960714869,0.3060621463513644,-0.48932157771479984,0.875822884605927,1.4653001660607239,0.2849798960714869,0.7768548054179463,-0.7010844658862807,0.4106794033765102,0.5345151608497005,-2.110732770289434,0.6160695351919047,0.027706804197958748,0.7169170935451981,2.2901630892549574,-0.3740674450103724,0.09278259830834672,0.7967405306725779,0.5140024586389151,0.7768548054179463,0.027706804197958748,0.7169170935451981,-0.5358936496388635,-1.2442068622654376,0.07114797485870293,0.15734698889488374,2.748257927082434,-0.037890347716938104,1.7190419968762196,4.964265885140395,-0.5125735357359387,-0.14840553567250234,0.22140963170165096,0.5345151608497005,-0.5592824068345678,-0.17069011224710406,-0.1930361462854971,0.4314463011221435,1.9134596354218771,-0.44302020696238215,0.5957548236023519,0.856120860427004,1.1279179444266103 | 3,039 |
Vacuole organization | 17 | 49 | 2.797373 | 0.005152 | P11117,P16615,P04062,O14773,Q86Y82,Q9HC07,P54802,Q8N511,Q15286,O75503,Q14108,P07686,O75396,P10253,Q9P253,Q8TBX8,P50897 | Processes and pathways | GO Biological process | msigdb_gobp | 227,233,171,231,362,174,113,50,337,94,22,55,275,218,352,126,31 | 2458,231,275,94,2372,1833,171,2837,55,218,227,233,405,792,2248,31,896,113,2040,1055,680,704,22,2260,337,846,570,362,50,2754,126,2513,1666,2666,1148,2361,878,640,2932,174,2323,835,352,3018,1081,2280,2646,1776,1584 | -0.606267828635831,1.3542800263786563,1.2040279643762803,2.35701295367094,-0.5592824068345678,-0.3057028045175211,1.7190419968762196,-0.9678943672344994,2.859343234867589,1.409965539103894,1.3728811852532863,1.3542800263786563,0.7967405306725779,0.26384394974348613,-0.48932157771479984,3.470285289418032,0.17875648445362774,2.120868736002922,-0.39698574608401843,0.07114797485870293,0.36899000714620145,0.34806687646145595,3.7041893683460807,-0.48932157771479984,0.9930928138653216,0.22140963170165096,0.5140024586389151,0.9150913335574359,3.0312996064863214,-0.8454869482570131,2.052259319406885,-0.629865496214547,-0.21544405120141735,-0.7489239882266361,0.027706804197958748,-0.5358936496388635,0.20011058306743956,0.4314463011221435,-1.2442068622654376,1.7190419968762196,-0.5125735357359387,0.24265397388246301,0.9541806525094901,-2.4338801984065768,0.07114797485870293,-0.48932157771479984,-0.724967851906094,-0.2604471495603937,-0.17069011224710406 | 3,039 |
Progressive neurologic deterioration | 10 | 21 | 2.79679 | 0.005161 | P15289,Q10713,P07602,P04062,O43681,P16278,P54802,Q7LG56,Q5XKP0,P07686 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 355,197,43,171,332,16,113,212,406,55 | 332,171,43,55,1595,355,16,761,789,2340,2383,113,1788,2085,197,1799,406,2509,212,2668,457 | 1.0124830674261933,1.7190419968762196,3.154426526604387,2.859343234867589,-0.1930361462854971,0.9346582601951924,3.9467246428005365,0.2849798960714869,0.26384394974348613,-0.5358936496388635,-0.5592824068345678,2.120868736002922,-0.2830431922681599,-0.4199698464474526,1.5385430296065519,-0.2830431922681599,0.7967405306725779,-0.629865496214547,1.4653001660607239,-0.7489239882266361,0.7169170935451981 | 3,039 |
Endoplasmic reticulum golgi intermediate compartment | 14 | 47 | 2.793854 | 0.005208 | P24390,P80303,Q15363,O95070,Q10472,P49257,Q02818,Q8N511,Q9Y3B3,Q9Y282,Q9BVK6,O75396,O15260,P51572 | Localization | GO Cellular component | msigdb_gocc | 1,33,65,287,203,269,300,50,309,213,381,275,27,251 | 526,27,549,275,287,982,1298,1,2771,1930,269,387,1311,251,2783,630,1741,898,33,300,1748,203,765,1609,1101,2261,65,768,2399,2268,50,2049,2924,906,938,2807,381,2919,878,2453,2487,2416,213,564,309,2367,914 | 0.5753910503793658,3.6025482837872342,0.5345151608497005,1.2040279643762803,1.166056404831489,0.11436040160061789,-0.059873687391535715,5.339593503895038,-0.8698150771053541,-0.35121448743560607,1.2229517085712236,0.856120860427004,-0.059873687391535715,1.2982381726059844,-0.8942192990435678,0.4314463011221435,-0.2604471495603937,0.17875648445362774,3.4554772633739423,1.1279179444266103,-0.2604471495603937,1.5019976151465506,0.2849798960714869,-0.1930361462854971,0.04945616636338176,-0.48932157771479984,2.748257927082434,0.2849798960714869,-0.5592824068345678,-0.48932157771479984,3.0312996064863214,-0.39698574608401843,-1.1932239737205523,0.17875648445362774,0.15734698889488374,-0.9187001949064155,0.875822884605927,-1.167859218190506,0.20011058306743956,-0.5827403002940941,-0.606267828635831,-0.5592824068345678,1.446893946428851,0.5345151608497005,1.1087855671016753,-0.5358936496388635,0.17875648445362774 | 3,039 |
Variable expressivity | 15 | 76 | 2.793046 | 0.005221 | P00403,Q13510,P03886,Q13885,Q70HW3,Q15125,Q9Y276,Q9H061,P04350,P07602,O95470,Q96AD5,P17900,Q9BVA1,Q9BUF5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 226,6,38,168,137,10,144,12,167,43,140,240,152,153,222 | 3030,1381,860,1382,1296,2372,2066,140,393,226,1979,38,167,1594,1169,43,1781,1595,720,310,152,2294,1017,1391,2194,1130,2744,1250,1092,487,2469,1309,2198,2978,2746,1936,2085,1359,1257,871,2136,746,2912,1408,6,1556,1796,168,2004,10,1755,651,2215,2308,686,687,137,1146,388,2222,240,222,153,12,2999,1230,2056,457,1233,591,694,144,1922,248,644,1343 | -3.4336046535863733,-0.10401912304964674,0.20011058306743956,-0.10401912304964674,-0.059873687391535715,-0.5592824068345678,-0.4199698464474526,1.9134596354218771,0.8363732981403815,1.3728811852532863,-0.3740674450103724,3.275983050297943,1.736891982086496,-0.1930361462854971,0.005899515949245535,3.154426526604387,-0.2830431922681599,-0.1930361462854971,0.32709103081034985,1.0896107895774603,1.8608535136088946,-0.5125735357359387,0.09278259830834672,-0.10401912304964674,-0.46613729363893336,0.027706804197958748,-0.8454869482570131,-0.037890347716938104,0.04945616636338176,0.6363354713395758,-0.606267828635831,-0.059873687391535715,-0.46613729363893336,-1.5308885852988285,-0.8454869482570131,-0.35121448743560607,-0.4199698464474526,-0.08191648177571846,-0.037890347716938104,0.20011058306743956,-0.44302020696238215,0.3060621463513644,-1.142578020067442,-0.10401912304964674,4.797294388390134,-0.17069011224710406,-0.2830431922681599,1.736891982086496,-0.3740674450103724,4.2383322485299875,-0.2604471495603937,0.4106794033765102,-0.46613729363893336,-0.5125735357359387,0.36899000714620145,0.36899000714620145,1.9309268460754112,0.027706804197958748,0.856120860427004,-0.46613729363893336,1.3356392751731447,1.409965539103894,1.8608535136088946,4.058825415756852,-1.8289388777427835,-0.01596607463826186,-0.39698574608401843,0.7169170935451981,-0.01596607463826186,0.4934395229159375,0.36899000714620145,1.9134596354218771,-0.3284264225634382,1.3169587262701798,0.4314463011221435,-0.059873687391535715 | 3,039 |
Vacuolar membrane | 26 | 114 | 2.785377 | 0.005347 | Q93050,Q9UIQ6,P10619,Q14108,Q14849,O15260,P07602,P04062,Q9HC07,P42785,Q8N511,Q92542,Q8TCT8,P42892,Q07065,Q9H2V7,P10253,P51790,O75503,O15118,Q8WTV0,P11117,P51798,Q8IV08,O95772,P13473 | Localization | GO Cellular component | msigdb_gocc | 136,143,145,22,25,27,43,171,174,47,50,183,188,68,202,87,218,219,94,93,96,227,101,103,110,111 | 2458,2421,779,93,27,2628,1434,1588,2288,94,373,1589,110,1727,171,1199,2837,43,1981,783,1480,1385,863,218,145,227,1537,607,111,583,1246,1888,2426,234,1052,891,2632,2194,2129,2654,792,47,68,2430,763,896,219,101,367,815,2040,898,1055,844,1746,544,1551,2136,1849,202,555,2748,2257,22,25,2213,846,570,103,752,50,664,710,188,96,2873,183,136,1666,1564,1509,2974,1148,547,2757,1111,363,3038,1863,908,851,640,87,2517,174,1287,2989,835,457,1773,1338,352,2847,1190,143,1675,620,1081,981,1526,2646,1776,420,1342 | -0.606267828635831,-0.5827403002940941,0.26384394974348613,2.35701295367094,3.6025482837872342,-0.724967851906094,-0.12618200751855965,-0.1930361462854971,-0.5125735357359387,2.35701295367094,0.875822884605927,-0.1930361462854971,2.137940388935406,-0.2604471495603937,1.7190419968762196,-0.01596607463826186,-0.9678943672344994,3.154426526604387,-0.3740674450103724,0.26384394974348613,-0.14840553567250234,-0.10401912304964674,0.20011058306743956,1.409965539103894,1.895958450657215,1.3728811852532863,-0.17069011224710406,0.4521617483820871,2.137940388935406,0.4934395229159375,-0.037890347716938104,-0.3284264225634382,-0.5827403002940941,1.3542800263786563,0.07114797485870293,0.17875648445362774,-0.724967851906094,-0.46613729363893336,-0.44302020696238215,-0.7489239882266361,0.26384394974348613,3.123793940195311,2.716275809025029,-0.5827403002940941,0.2849798960714869,0.17875648445362774,1.409965539103894,2.273374172038848,0.895479624968376,0.24265397388246301,-0.39698574608401843,0.17875648445362774,0.07114797485870293,0.22140963170165096,-0.2604471495603937,0.5549779266548395,-0.17069011224710406,-0.44302020696238215,-0.3057028045175211,1.5019976151465506,0.5345151608497005,-0.8454869482570131,-0.48932157771479984,3.7041893683460807,3.646238633225624,-0.46613729363893336,0.22140963170165096,0.5140024586389151,2.273374172038848,0.3060621463513644,3.0312996064863214,0.3898607435766084,0.34806687646145595,1.5930794075923984,2.3236489114327066,-1.0422756142123357,1.6652764555563804,1.9483602424077069,-0.21544405120141735,-0.17069011224710406,-0.14840553567250234,-1.477950289982449,0.027706804197958748,0.5549779266548395,-0.8454869482570131,0.04945616636338176,0.9150913335574359,-14.138461661029716,-0.3057028045175211,0.17875648445362774,0.22140963170165096,0.4314463011221435,2.4233799652318058,-0.629865496214547,1.7190419968762196,-0.037890347716938104,-1.719172153536557,0.24265397388246301,0.7169170935451981,-0.2604471495603937,-0.059873687391535715,0.9541806525094901,-0.9678943672344994,0.005899515949245535,1.9134596354218771,-0.21544405120141735,0.4521617483820871,0.07114797485870293,0.13588174593938243,-0.14840553567250234,-0.724967851906094,-0.2604471495603937,0.7768548054179463,-0.059873687391535715 | 3,039 |
Endomembrane system organization | 53 | 171 | 2.777664 | 0.005475 | O43760,P49755,Q16739,P31751,P49257,Q92783,Q9UNF0,Q9ULX6,Q14108,P46379,O75396,Q8WUM4,O15260,Q9BRG1,Q96A33,P78537,Q8NC56,Q9H2C2,O43752,Q9Y3A6,Q53FT3,Q5J8M3,Q86XL3,Q9UP83,Q96CP7,Q9Y3B3,Q7Z3C6,Q15363,P31749,Q8N3F8,O75844,Q6P1A2,O43681,Q9P2W9,Q9UQB8,Q15629,Q8N5M9,P51790,Q9P253,P57088,Q8N4V1,Q9UID3,Q9BTU6,P16615,P27361,O95197,P61020,Q00765,Q8IXJ6,Q9BVK6,Q7Z3D4,O75955,Q9NQC3 | Processes and pathways | GO Biological process | msigdb_gobp | 257,387,265,268,269,398,539,538,22,23,275,409,27,548,418,544,292,163,541,564,415,556,49,444,178,309,570,65,196,451,73,200,332,82,210,211,344,219,352,476,99,500,363,233,237,112,368,370,247,381,510,373,127 | 1119,2029,1381,2421,1972,1237,1347,1431,1082,27,2520,1633,332,541,257,565,1881,2461,2424,275,2859,2739,73,373,781,2740,112,1590,1979,758,1981,233,2592,761,2706,237,196,268,1249,955,1645,2654,2080,1250,23,2430,892,269,387,676,925,896,219,2084,1741,476,1650,898,368,1210,2252,680,1056,544,870,370,1057,2254,1748,704,820,765,632,660,1793,1609,22,1366,1411,2603,1101,766,749,2260,1944,1800,65,211,265,1502,1659,415,556,1182,1104,2896,846,200,903,3007,1065,2637,570,510,2267,2146,49,1144,247,827,1105,451,99,344,2010,292,2048,2754,2613,2218,1419,2942,409,2049,1952,2924,398,418,178,2974,2223,1569,548,1707,363,1708,381,1709,851,163,2932,976,1074,942,1231,1038,127,835,1377,1773,1338,352,82,500,1159,1379,538,539,3018,444,210,1081,2456,2280,778,2646,564,309,1776,1161,914 | 0.027706804197958748,-0.39698574608401843,-0.10401912304964674,-0.5827403002940941,-0.3740674450103724,-0.037890347716938104,-0.08191648177571846,-0.12618200751855965,0.04945616636338176,3.6025482837872342,-0.6535338132122217,-0.21544405120141735,1.0124830674261933,0.5549779266548395,1.2794774054002804,0.5140024586389151,-0.3284264225634382,-0.606267828635831,-0.5827403002940941,1.2040279643762803,-1.0174023844038849,-0.8454869482570131,2.668096362263561,0.875822884605927,0.26384394974348613,-0.8454869482570131,2.120868736002922,-0.1930361462854971,-0.3740674450103724,0.2849798960714869,-0.3740674450103724,1.3542800263786563,-0.7010844658862807,0.2849798960714869,-0.7970566811673792,1.3356392751731447,1.5385430296065519,1.2229517085712236,-0.037890347716938104,0.13588174593938243,-0.21544405120141735,-0.7489239882266361,-0.4199698464474526,-0.037890347716938104,3.675257034989104,-0.5827403002940941,0.17875648445362774,1.2229517085712236,0.856120860427004,0.36899000714620145,0.15734698889488374,0.17875648445362774,1.409965539103894,-0.4199698464474526,-0.2604471495603937,0.6565529155942527,-0.21544405120141735,0.17875648445362774,0.895479624968376,-0.01596607463826186,-0.48932157771479984,0.36899000714620145,0.07114797485870293,0.5549779266548395,0.20011058306743956,0.895479624968376,0.07114797485870293,-0.48932157771479984,-0.2604471495603937,0.34806687646145595,0.24265397388246301,0.2849798960714869,0.4314463011221435,0.3898607435766084,-0.2830431922681599,-0.1930361462854971,3.7041893683460807,-0.08191648177571846,-0.10401912304964674,-0.7010844658862807,0.04945616636338176,0.2849798960714869,0.3060621463513644,-0.48932157771479984,-0.35121448743560607,-0.2830431922681599,2.748257927082434,1.4653001660607239,1.2418343865431385,-0.14840553567250234,-0.21544405120141735,0.7768548054179463,0.5345151608497005,0.005899515949245535,0.04945616636338176,-1.0922636419622016,0.22140963170165096,1.5202892310550606,0.17875648445362774,-2.110732770289434,0.07114797485870293,-0.724967851906094,0.5140024586389151,0.6160695351919047,-0.48932157771479984,-0.44302020696238215,3.04677804479763,0.027706804197958748,1.3169587262701798,0.24265397388246301,0.04945616636338176,0.7169170935451981,2.2901630892549574,0.9736587559602312,-0.3740674450103724,1.166056404831489,-0.39698574608401843,-0.8454869482570131,-0.7010844658862807,-0.46613729363893336,-0.10401912304964674,-1.2955321839628167,0.7967405306725779,-0.39698574608401843,-0.35121448743560607,-1.1932239737205523,0.8363732981403815,0.7768548054179463,1.6832344093740115,-1.477950289982449,-0.46613729363893336,-0.17069011224710406,0.5549779266548395,-0.23791424484342957,0.9150913335574359,-0.23791424484342957,0.875822884605927,-0.23791424484342957,0.22140963170165096,1.7902287843769074,-1.2442068622654376,0.13588174593938243,0.07114797485870293,0.15734698889488374,-0.01596607463826186,0.09278259830834672,2.0350255192397007,0.24265397388246301,-0.08191648177571846,-0.2604471495603937,-0.059873687391535715,0.9541806525094901,2.5546987479486667,0.6363354713395758,0.027706804197958748,-0.08191648177571846,0.5753910503793658,0.5753910503793658,-2.4338801984065768,0.7369433540186023,1.483667990965456,0.07114797485870293,-0.5827403002940941,-0.48932157771479984,0.2849798960714869,-0.724967851906094,0.5345151608497005,1.1087855671016753,-0.2604471495603937,0.027706804197958748,0.17875648445362774 | 3,039 |
Gap junction | 6 | 15 | 2.775702 | 0.005508 | Q13885,P07437,P04350,Q9BVA1,P68371,Q9BUF5 | Processes and pathways | KEGG Pathways | msigdb_kegg | 168,105,167,153,124,222 | 167,1593,758,105,1385,1731,237,955,1316,124,2254,1901,168,222,153 | 1.736891982086496,-0.1930361462854971,0.2849798960714869,2.205908584221655,-0.10401912304964674,-0.2604471495603937,1.3356392751731447,0.13588174593938243,-0.059873687391535715,2.0694603911174667,-0.48932157771479984,-0.3284264225634382,1.736891982086496,1.409965539103894,1.8608535136088946 | 3,039 |
Retrograde transport endosome to golgi | 15 | 35 | 2.771411 | 0.005581 | Q4J6C6,O43752,Q93009,Q9UID3,Q13596,O95249,P49257,O60749,Q4KMP7,Q8NBN3,Q9BVK6,O15260,O75503,Q9Y5X3,P53367 | Processes and pathways | GO Biological process | msigdb_gobp | 414,541,325,500,394,262,269,176,350,215,381,27,94,458,376 | 27,549,541,1434,176,1722,94,262,1641,1645,269,896,376,2136,1609,394,1411,414,350,1757,1144,215,2049,325,1148,381,2020,2847,1079,500,1628,1291,945,2556,458 | 3.6025482837872342,0.5345151608497005,0.5549779266548395,-0.12618200751855965,1.7011561976657679,-0.2604471495603937,2.35701295367094,1.2418343865431385,-0.21544405120141735,-0.21544405120141735,1.2229517085712236,0.17875648445362774,0.875822884605927,-0.44302020696238215,-0.1930361462854971,0.8363732981403815,-0.10401912304964674,0.7768548054179463,0.9541806525094901,-0.2604471495603937,0.027706804197958748,1.4284491364966743,-0.39698574608401843,1.0511331158891664,0.027706804197958748,0.875822884605927,-0.3740674450103724,-0.9678943672344994,0.07114797485870293,0.6363354713395758,-0.1930361462854971,-0.037890347716938104,0.15734698889488374,-0.6535338132122217,0.7169170935451981 | 3,039 |
Membrane lipid catabolic process | 8 | 11 | 2.76656 | 0.005665 | P06280,P06865,Q13510,P04062,O95470,P07686,P17900,P50897 | Processes and pathways | GO Biological process | msigdb_gobp | 191,100,6,171,140,55,152,31 | 140,171,295,191,100,55,152,31,6,655,1377 | 1.9134596354218771,1.7190419968762196,1.1470081486218546,1.574937930723592,2.273374172038848,2.859343234867589,1.8608535136088946,3.470285289418032,4.797294388390134,0.4106794033765102,-0.08191648177571846 | 3,039 |
Biliary tract abnormality | 12 | 26 | 2.762564 | 0.005735 | P15289,Q14739,Q10713,Q9NSD9,Q9Y276,P07602,P09601,P04062,O43681,P14174,Q5XKP0,Q14108 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 355,260,197,432,144,43,13,171,332,80,406,22 | 332,782,1168,1979,171,43,13,80,355,2970,1786,1132,1253,2746,197,682,2393,22,260,406,2446,432,457,670,144,737 | 1.0124830674261933,0.26384394974348613,0.005899515949245535,-0.3740674450103724,1.7190419968762196,3.154426526604387,4.030919006514059,2.5546987479486667,0.9346582601951924,-1.477950289982449,-0.2830431922681599,0.027706804197958748,-0.037890347716938104,-0.8454869482570131,1.5385430296065519,0.36899000714620145,-0.5592824068345678,3.7041893683460807,1.2606762141367405,0.7967405306725779,-0.5827403002940941,0.7569225018513692,0.7169170935451981,0.3898607435766084,1.9134596354218771,0.32709103081034985 | 3,039 |
Cation transport | 49 | 144 | 2.762437 | 0.005737 | P21796,O95747,Q92504,O43772,O75964,Q8WWI5,Q70HW3,P13073,Q9Y289,Q96QD8,P20674,Q07812,P24539,Q9HC07,P62942,O15173,Q9H2J7,Q9UDW1,Q8WWC4,P00846,Q9H936,Q9HD20,Q9UM00,P31749,Q96PU5,P24941,O75844,O43865,P05023,P56134,Q13555,Q8NEW0,Q96ES6,P51790,O43808,Q9HC21,Q8N4V1,P00403,Q13423,P27105,P30536,P16615,Q9Y4W6,P51809,Q9H9B4,Q7KZN9,Q9Y619,O76024,Q12955 | Processes and pathways | GO Biological process | msigdb_gobp | 4,504,131,129,134,266,137,386,540,270,32,545,289,174,554,51,442,54,572,63,456,66,323,196,70,447,73,333,334,602,471,345,346,219,353,618,99,226,102,234,235,233,644,367,641,371,382,484,632 | 1381,915,1237,738,51,860,129,353,333,1976,1043,1044,2424,2333,73,697,134,484,782,504,226,63,1383,1593,334,757,1200,698,2837,1926,1981,783,1243,740,2463,1014,759,386,865,233,1731,2770,2965,760,627,32,1246,1888,2878,4,289,447,1387,234,1483,2428,235,1541,196,2379,891,743,1893,1486,2632,2194,2080,2430,647,1740,2562,925,219,367,2386,959,2784,602,816,1547,844,2252,961,554,1262,928,745,2136,1655,930,725,545,1318,797,2748,632,102,471,2262,900,2141,2307,1659,1760,137,371,1910,99,801,345,572,266,131,1225,346,2665,875,70,270,2756,1335,2915,775,2808,442,1575,456,641,174,618,66,2989,54,2416,1190,1290,323,2061,945,540,1117,644,382,3006 | -0.10401912304964674,0.15734698889488374,-0.037890347716938104,0.3060621463513644,3.0002666726045604,0.20011058306743956,2.0004591255918744,0.9346582601951924,1.0124830674261933,-0.3740674450103724,0.07114797485870293,0.07114797485870293,-0.5827403002940941,-0.5358936496388635,2.668096362263561,0.34806687646145595,1.9657599830182004,0.6363354713395758,0.26384394974348613,0.6160695351919047,1.3728811852532863,2.7642080742589887,-0.10401912304964674,-0.1930361462854971,1.0124830674261933,0.2849798960714869,-0.01596607463826186,0.34806687646145595,-0.9678943672344994,-0.35121448743560607,-0.3740674450103724,0.26384394974348613,-0.037890347716938104,0.3060621463513644,-0.606267828635831,0.09278259830834672,0.2849798960714869,0.856120860427004,0.20011058306743956,1.3542800263786563,-0.2604471495603937,-0.8698150771053541,-1.451619920580497,0.2849798960714869,0.4314463011221435,3.4554772633739423,-0.037890347716938104,-0.3284264225634382,-1.067229155753125,5.053064615984644,1.166056404831489,0.7169170935451981,-0.10401912304964674,1.3542800263786563,-0.14840553567250234,-0.5827403002940941,1.3542800263786563,-0.17069011224710406,1.5385430296065519,-0.5592824068345678,0.17875648445362774,0.3060621463513644,-0.3284264225634382,-0.14840553567250234,-0.724967851906094,-0.46613729363893336,-0.4199698464474526,-0.5827403002940941,0.4106794033765102,-0.2604471495603937,-0.6772732957307089,0.15734698889488374,1.409965539103894,0.895479624968376,-0.5592824068345678,0.13588174593938243,-0.8942192990435678,0.47282605375654435,0.24265397388246301,-0.17069011224710406,0.22140963170165096,-0.48932157771479984,0.13588174593938243,0.5345151608497005,-0.037890347716938104,0.15734698889488374,0.3060621463513644,-0.44302020696238215,-0.21544405120141735,0.15734698889488374,0.32709103081034985,0.5549779266548395,-0.059873687391535715,0.26384394974348613,-0.8454869482570131,0.4314463011221435,2.273374172038848,0.6767221488954713,-0.48932157771479984,0.17875648445362774,-0.44302020696238215,-0.5125735357359387,-0.21544405120141735,-0.2604471495603937,1.9309268460754112,0.895479624968376,-0.3284264225634382,2.2901630892549574,0.26384394974348613,0.9736587559602312,0.5140024586389151,1.2418343865431385,2.0004591255918744,-0.01596607463826186,0.9736587559602312,-0.7489239882266361,0.20011058306743956,2.7002436108444896,1.2229517085712236,-0.8454869482570131,-0.059873687391535715,-1.142578020067442,0.2849798960714869,-0.9187001949064155,0.7369433540186023,-0.17069011224710406,0.7169170935451981,0.4314463011221435,1.7190419968762196,0.4521617483820871,2.748257927082434,-1.719172153536557,2.890842077222198,-0.5592824068345678,0.005899515949245535,-0.037890347716938104,1.070393382836239,-0.39698574608401843,0.15734698889488374,0.5753910503793658,0.04945616636338176,0.4314463011221435,0.875822884605927,-2.0820597615696625 | 3,039 |
Arthritis | 12 | 38 | 2.760185 | 0.005777 | Q14739,P51798,Q13510,O75844,P04062,Q9NZ08,Q96HY6,P14174,Q9Y3Z3,Q14108,P21964,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,101,6,73,171,341,439,80,248,22,317,191 | 1120,2648,1475,73,1592,1979,171,191,1781,864,2032,80,317,2426,463,1602,2248,101,2250,1996,1491,2252,1552,1058,6,22,260,1852,2973,709,1562,439,547,1154,1712,341,778,248 | 0.027706804197958748,-0.7489239882266361,-0.14840553567250234,2.668096362263561,-0.1930361462854971,-0.3740674450103724,1.7190419968762196,1.574937930723592,-0.2830431922681599,0.20011058306743956,-0.39698574608401843,2.5546987479486667,1.070393382836239,-0.5827403002940941,0.69684344960622,-0.1930361462854971,-0.48932157771479984,2.273374172038848,-0.48932157771479984,-0.3740674450103724,-0.14840553567250234,-0.48932157771479984,-0.17069011224710406,0.07114797485870293,4.797294388390134,3.7041893683460807,1.2606762141367405,-0.3057028045175211,-1.477950289982449,0.34806687646145595,-0.17069011224710406,0.7369433540186023,0.5549779266548395,0.027706804197958748,-0.23791424484342957,0.9930928138653216,0.2849798960714869,1.3169587262701798 | 3,039 |
Cilium assembly | 11 | 67 | 2.756694 | 0.005839 | Q9BVA1,Q10713,Q13885,A6NIH7,P07437,O43924,P04350,O95684,O43805,O75695,P68371 | Processes and pathways | Reactome Pathways | msigdb_reactome | 153,197,168,40,105,42,167,150,24,122,124 | 592,40,1971,24,42,696,122,384,551,150,167,758,105,1479,1731,951,1442,2294,843,1932,1306,1250,600,1544,2298,1546,2084,1054,609,1098,961,2772,124,1175,197,1265,611,168,2749,1411,2729,726,965,1413,824,2267,2511,800,827,2048,1950,1951,2049,417,1108,1278,712,1565,2576,222,153,2156,481,2160,1189,2057,1005 | 0.47282605375654435,3.245738490444791,-0.3740674450103724,3.646238633225624,3.1697059703407153,0.34806687646145595,2.0866288849685453,0.856120860427004,0.5345151608497005,1.8784231307888182,1.736891982086496,0.2849798960714869,2.205908584221655,-0.14840553567250234,-0.2604471495603937,0.13588174593938243,-0.12618200751855965,-0.5125735357359387,0.22140963170165096,-0.35121448743560607,-0.059873687391535715,-0.037890347716938104,0.47282605375654435,-0.17069011224710406,-0.5125735357359387,-0.17069011224710406,-0.4199698464474526,0.07114797485870293,0.4521617483820871,0.04945616636338176,0.13588174593938243,-0.8698150771053541,2.0694603911174667,0.005899515949245535,1.5385430296065519,-0.037890347716938104,0.4521617483820871,1.736891982086496,-0.8454869482570131,-0.10401912304964674,-0.8212343386218275,0.32709103081034985,0.13588174593938243,-0.10401912304964674,0.24265397388246301,-0.48932157771479984,-0.629865496214547,0.26384394974348613,0.24265397388246301,-0.39698574608401843,-0.35121448743560607,-0.35121448743560607,-0.39698574608401843,0.7768548054179463,0.04945616636338176,-0.037890347716938104,0.34806687646145595,-0.17069011224710406,-0.6772732957307089,1.409965539103894,1.8608535136088946,-0.44302020696238215,0.6565529155942527,-0.44302020696238215,0.005899515949245535,-0.39698574608401843,0.11436040160061789 | 3,039 |
Metabolism of steroids | 17 | 49 | 2.753082 | 0.005904 | Q9H2C2,Q14739,Q15800,P38435,Q15125,P04062,P37268,P30536,O95772,Q15392,Q9BWD1,P48449,Q14534,Q16850,P14324,Q14849,Q99538 | Processes and pathways | Reactome Pathways | msigdb_reactome | 163,260,264,263,10,171,236,235,110,281,179,278,148,52,118,25,221 | 3035,622,1039,324,1167,1637,110,171,118,1538,2706,646,2125,235,236,263,278,1602,1253,2385,1996,867,1315,3002,1058,3036,2658,148,260,25,1320,10,1453,281,1136,1026,264,52,427,1458,848,1705,221,179,163,776,515,1626,1008 | -4.013890522384447,0.4314463011221435,0.07114797485870293,1.0511331158891664,0.005899515949245535,-0.21544405120141735,2.137940388935406,1.7190419968762196,2.1037649504595,-0.17069011224710406,-0.7970566811673792,0.4106794033765102,-0.44302020696238215,1.3542800263786563,1.3542800263786563,1.2418343865431385,1.2040279643762803,-0.1930361462854971,-0.037890347716938104,-0.5592824068345678,-0.3740674450103724,0.20011058306743956,-0.059873687391535715,-1.9967112632049284,0.07114797485870293,-4.404868850320807,-0.7489239882266361,1.895958450657215,1.2606762141367405,3.646238633225624,-0.059873687391535715,4.2383322485299875,-0.12618200751855965,1.2040279643762803,0.027706804197958748,0.09278259830834672,1.2418343865431385,2.9847119746833544,0.7569225018513692,-0.12618200751855965,0.22140963170165096,-0.23791424484342957,1.409965539103894,1.6832344093740115,1.7902287843769074,0.2849798960714869,0.6160695351919047,-0.1930361462854971,0.11436040160061789 | 3,039 |
Sphingolipid metabolism | 9 | 12 | 2.75202 | 0.005923 | Q13510,Q16739,O15269,O43681,P04062,O95470,P16278,Q06136,P06280 | Processes and pathways | KEGG Pathways | msigdb_kegg | 6,265,347,332,171,140,16,349,191 | 347,595,332,140,171,191,355,16,349,6,265,1377 | 0.9541806525094901,0.47282605375654435,1.0124830674261933,1.9134596354218771,1.7190419968762196,1.574937930723592,0.9346582601951924,3.9467246428005365,0.9541806525094901,4.797294388390134,1.2418343865431385,-0.08191648177571846 | 3,039 |
Alcohol binding | 6 | 14 | 2.7494 | 0.00597 | P21796,P45880,O95772,Q14108,Q14849,O15118 | Functions | GO Molecular function | msigdb_gomf | 4,7,110,22,25,93 | 2909,93,1382,887,110,1981,4,646,235,7,22,25,639,776 | -1.142578020067442,2.35701295367094,-0.10401912304964674,0.17875648445362774,2.137940388935406,-0.3740674450103724,5.053064615984644,0.4106794033765102,1.3542800263786563,4.548247176509721,3.7041893683460807,3.646238633225624,0.4314463011221435,0.2849798960714869 | 3,039 |
Cholesterol metabolism | 10 | 24 | 2.747922 | 0.005997 | Q9H2C2,Q14739,Q15800,P37268,Q15125,P04062,Q15392,Q16850,P14324,O15118 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 163,260,264,236,10,171,281,52,118,93 | 93,324,887,1439,171,118,2125,236,2385,413,1998,3002,1058,2658,260,10,1453,281,1026,264,52,163,1626,2327 | 2.35701295367094,1.0511331158891664,0.17875648445362774,-0.12618200751855965,1.7190419968762196,2.1037649504595,-0.44302020696238215,1.3542800263786563,-0.5592824068345678,0.7768548054179463,-0.3740674450103724,-1.9967112632049284,0.07114797485870293,-0.7489239882266361,1.2606762141367405,4.2383322485299875,-0.12618200751855965,1.2040279643762803,0.09278259830834672,1.2418343865431385,2.9847119746833544,1.7902287843769074,-0.1930361462854971,-0.5125735357359387 | 3,039 |
Intrinsic component of mitochondrial membrane | 28 | 47 | 2.747643 | 0.006003 | O60830,P12235,Q9Y512,Q13505,Q99595,Q53H12,Q5XKP0,Q9H9P8,Q9Y2R0,Q6P4A7,Q16134,P57105,Q9NVH1,O14925,Q9NX63,Q9HC21,O75880,Q9BUB7,Q6UXV4,Q9Y4W6,O75431,Q9H9B4,Q15388,Q9BUR5,P50416,Q9UG56,Q15070,Q16891 | Localization | GO Cellular component | msigdb_gocc | 3,759,525,135,9,651,406,156,30,686,313,312,714,214,482,618,474,616,613,644,739,641,114,638,245,517,378,770 | 214,3,739,474,2178,2372,2704,862,759,2561,895,245,312,928,135,378,114,313,2141,770,651,1695,406,686,613,826,1145,1461,801,1618,875,9,2915,616,638,641,156,618,2989,2486,714,482,517,854,30,644,525 | 1.4284491364966743,5.053064615984644,0.3060621463513644,0.6565529155942527,-0.46613729363893336,-0.5592824068345678,-0.7970566811673792,0.20011058306743956,0.2849798960714869,-0.6772732957307089,0.17875648445362774,1.3169587262701798,1.0896107895774603,0.15734698889488374,1.9657599830182004,0.875822884605927,2.120868736002922,1.0896107895774603,-0.44302020696238215,0.2849798960714869,0.4106794033765102,-0.23791424484342957,0.7967405306725779,0.36899000714620145,0.4521617483820871,0.24265397388246301,0.027706804197958748,-0.12618200751855965,0.26384394974348613,-0.1930361462854971,0.20011058306743956,4.495028981433672,-1.142578020067442,0.4521617483820871,0.4314463011221435,0.4314463011221435,1.843249435681901,0.4521617483820871,-1.719172153536557,-0.606267828635831,0.34806687646145595,0.6565529155942527,0.6160695351919047,0.22140963170165096,3.5439873534993933,0.4314463011221435,0.5957548236023519 | 3,039 |
Cholesterol binding | 6 | 12 | 2.747302 | 0.006009 | P21796,P45880,O95772,Q14108,Q14849,O15118 | Functions | GO Molecular function | msigdb_gomf | 4,7,110,22,25,93 | 93,887,110,1981,4,646,235,7,22,25,639,776 | 2.35701295367094,0.17875648445362774,2.137940388935406,-0.3740674450103724,5.053064615984644,0.4106794033765102,1.3542800263786563,4.548247176509721,3.7041893683460807,3.646238633225624,0.4314463011221435,0.2849798960714869 | 3,039 |
Progressive visual loss | 6 | 21 | 2.741955 | 0.006107 | P31749,P03886,O75306,P50897,O75503,P00846 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 196,38,182,31,94,63 | 1120,1381,231,461,182,94,2372,63,38,2850,2493,2687,1642,196,743,1932,31,1799,1505,731,1277 | 0.027706804197958748,-0.10401912304964674,1.3542800263786563,0.69684344960622,1.6652764555563804,2.35701295367094,-0.5592824068345678,2.7642080742589887,3.275983050297943,-0.9926088412170806,-0.629865496214547,-0.7729534155941898,-0.21544405120141735,1.5385430296065519,0.3060621463513644,-0.35121448743560607,3.470285289418032,-0.2830431922681599,-0.14840553567250234,0.32709103081034985,-0.037890347716938104 | 3,039 |
Secretory vesicle | 55 | 247 | 2.738309 | 0.006176 | O43760,P49755,Q13510,P45880,Q93050,Q7L0J3,Q9H7Z7,P16278,P10619,P30519,P20339,Q969Q5,P35613,P17900,O15260,Q08380,P50897,Q92520,O00584,P04066,P07602,P42785,P07686,Q92542,Q96A57,Q9NUQ9,P15586,P06280,P09960,Q15363,P42892,Q9BTY2,O00264,Q07065,O43681,P20618,Q8NBM8,P14174,Q9UQB8,Q8NBX0,Q15286,Q99536,P10253,P51790,P12956,P15289,P06865,P27105,P07437,Q86Y82,P13473,P51809,P61020,Q9BVK6,P68371 | Localization | GO Cellular component | msigdb_gocc | 257,387,6,7,136,395,271,16,145,19,405,282,277,152,27,291,31,293,166,295,43,47,55,183,185,316,187,191,192,65,68,198,327,202,332,207,340,80,210,84,337,217,218,219,354,355,100,234,105,362,111,367,368,381,124 | 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| 3,039 |
Delusions | 10 | 18 | 2.729055 | 0.006352 | Q9BQE5,P15289,Q9UJS0,O00754,P04062,P07602,P36551,O43681,P21964,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,355,164,502,171,43,520,332,317,457 | 502,332,171,43,1013,355,317,520,2080,1018,895,798,2138,547,0,2547,457,164 | 0.6160695351919047,1.0124830674261933,1.7190419968762196,3.154426526604387,0.09278259830834672,0.9346582601951924,1.070393382836239,0.5957548236023519,-0.4199698464474526,0.09278259830834672,0.17875648445362774,0.26384394974348613,-0.44302020696238215,0.5549779266548395,6.006249952883581,-0.6535338132122217,0.7169170935451981,1.7902287843769074 | 3,039 |
Myoclonus | 16 | 84 | 2.723581 | 0.006458 | P27544,P00403,Q9H2C2,P31749,Q10713,P03886,Q13510,P07602,P04062,Q9UBX3,O14773,O75503,Q14108,Q96CU9,P00846,P50897 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 161,226,163,196,197,38,6,43,171,77,231,94,22,61,63,31 | 915,2765,231,738,2369,94,1725,2067,862,393,226,63,38,171,1297,43,1595,310,386,1785,1246,2593,161,1644,2340,196,2381,2193,628,2194,2080,2469,2881,2198,31,2745,1313,2746,1491,1098,2633,871,2136,470,964,1177,1849,797,197,1408,3010,6,1556,22,2729,2504,1757,2509,1271,2611,1763,1031,1146,1277,61,1564,1510,1703,2925,654,2857,1771,693,163,456,2161,2548,457,77,1081,2232,255,644,2762 | 0.15734698889488374,-0.8698150771053541,1.3542800263786563,0.3060621463513644,-0.5592824068345678,2.35701295367094,-0.2604471495603937,-0.4199698464474526,0.20011058306743956,0.8363732981403815,1.3728811852532863,2.7642080742589887,3.275983050297943,1.7190419968762196,-0.059873687391535715,3.154426526604387,-0.1930361462854971,1.0896107895774603,0.856120860427004,-0.2830431922681599,-0.037890347716938104,-0.7010844658862807,1.8079372376287888,-0.21544405120141735,-0.5358936496388635,1.5385430296065519,-0.5592824068345678,-0.46613729363893336,0.4314463011221435,-0.46613729363893336,-0.4199698464474526,-0.606267828635831,-1.067229155753125,-0.46613729363893336,3.470285289418032,-0.8454869482570131,-0.059873687391535715,-0.8454869482570131,-0.14840553567250234,0.04945616636338176,-0.724967851906094,0.20011058306743956,-0.44302020696238215,0.6767221488954713,0.13588174593938243,0.005899515949245535,-0.3057028045175211,0.26384394974348613,1.5385430296065519,-0.10401912304964674,-2.1684205196784307,4.797294388390134,-0.17069011224710406,3.7041893683460807,-0.8212343386218275,-0.629865496214547,-0.2604471495603937,-0.629865496214547,-0.037890347716938104,-0.7010844658862807,-0.2604471495603937,0.09278259830834672,0.027706804197958748,-0.037890347716938104,2.7801310971571085,-0.17069011224710406,-0.14840553567250234,-0.23791424484342957,-1.1932239737205523,0.4106794033765102,-0.9926088412170806,-0.2604471495603937,0.36899000714620145,1.7902287843769074,0.7169170935451981,-0.44302020696238215,-0.6535338132122217,0.7169170935451981,2.603467193814167,0.07114797485870293,-0.46613729363893336,1.2982381726059844,0.4314463011221435,-0.8454869482570131 | 3,039 |
Activation of nmda receptors and postsynaptic events | 8 | 22 | 2.708066 | 0.006768 | P54646,Q13885,P04350,P27361,Q14168,Q9BVA1,P68371,Q9BUF5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 413,168,167,237,239,153,124,222 | 738,167,1169,840,1596,1731,237,1398,1174,1357,1095,413,869,124,471,168,1366,239,2262,2751,222,153 | 0.3060621463513644,1.736891982086496,0.005899515949245535,0.22140963170165096,-0.1930361462854971,-0.2604471495603937,1.3356392751731447,-0.10401912304964674,0.005899515949245535,-0.08191648177571846,0.04945616636338176,0.7768548054179463,0.20011058306743956,2.0694603911174667,0.6767221488954713,1.736891982086496,-0.08191648177571846,1.3356392751731447,-0.48932157771479984,-0.8454869482570131,1.409965539103894,1.8608535136088946 | 3,039 |
Primary active transmembrane transporter activity | 15 | 49 | 2.705406 | 0.006822 | P20674,Q9HD20,P00403,P51798,P03886,P16615,P08183,O95168,P05023,Q15388,Q7KZN9,Q9UDW1,O75306,Q9Y6M9,O43676 | Functions | GO Molecular function | msigdb_gomf | 32,66,226,101,38,233,107,232,334,114,371,54,182,383,62 | 3030,915,779,2521,62,445,1043,1044,182,1239,232,1166,2651,505,226,38,334,698,107,1243,740,386,233,2033,760,32,1246,1888,986,2378,2379,2632,2194,2881,101,1356,844,114,1501,2307,371,66,2989,2486,1520,54,1190,1342,383 | -3.4336046535863733,0.15734698889488374,0.26384394974348613,-0.6535338132122217,2.7642080742589887,0.7169170935451981,0.07114797485870293,0.07114797485870293,1.6652764555563804,-0.037890347716938104,1.3542800263786563,0.005899515949245535,-0.7489239882266361,0.6160695351919047,1.3728811852532863,3.275983050297943,1.0124830674261933,0.34806687646145595,2.1719878809978588,-0.037890347716938104,0.3060621463513644,0.856120860427004,1.3542800263786563,-0.39698574608401843,0.2849798960714869,3.4554772633739423,-0.037890347716938104,-0.3284264225634382,0.11436040160061789,-0.5592824068345678,-0.5592824068345678,-0.724967851906094,-0.46613729363893336,-1.067229155753125,2.273374172038848,-0.08191648177571846,0.22140963170165096,2.120868736002922,-0.14840553567250234,-0.5125735357359387,0.895479624968376,2.748257927082434,-1.719172153536557,-0.606267828635831,-0.14840553567250234,2.890842077222198,0.005899515949245535,-0.059873687391535715,0.875822884605927 | 3,039 |
Blindness | 14 | 74 | 2.700792 | 0.006917 | P06865,P51798,P03886,P07602,P16278,Q9H6K4,O75306,P07686,P17900,O75695,Q96CU9,P00846,O43676,P50897 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 100,101,38,43,16,48,182,55,152,122,61,63,62,31 | 2419,1120,3030,656,1721,1121,550,62,1587,2177,1044,182,1239,2680,122,2587,505,2291,63,38,2850,3003,100,43,55,2335,16,152,2033,984,1642,789,2125,2378,2340,196,1842,743,1932,1786,1130,1602,1018,2881,2384,31,101,2978,343,2746,2255,798,1750,2138,1500,2309,2608,2266,361,2270,1330,2150,1373,1277,61,1001,2668,48,2547,341,457,1519,1343,383 | -0.5827403002940941,0.027706804197958748,-3.4336046535863733,0.3898607435766084,-0.2604471495603937,0.027706804197958748,0.5345151608497005,2.7642080742589887,-0.1930361462854971,-0.46613729363893336,0.07114797485870293,1.6652764555563804,-0.037890347716938104,-0.7729534155941898,2.0866288849685453,-0.7010844658862807,0.6160695351919047,-0.5125735357359387,2.7642080742589887,3.275983050297943,-0.9926088412170806,-2.0250500657604884,2.273374172038848,3.154426526604387,2.859343234867589,-0.5358936496388635,3.9467246428005365,1.8608535136088946,-0.39698574608401843,0.11436040160061789,-0.21544405120141735,0.26384394974348613,-0.44302020696238215,-0.5592824068345678,-0.5358936496388635,1.5385430296065519,-0.3057028045175211,0.3060621463513644,-0.35121448743560607,-0.2830431922681599,0.027706804197958748,-0.1930361462854971,0.09278259830834672,-1.067229155753125,-0.5592824068345678,3.470285289418032,2.273374172038848,-1.5308885852988285,0.9736587559602312,-0.8454869482570131,-0.48932157771479984,0.26384394974348613,-0.2604471495603937,-0.44302020696238215,-0.14840553567250234,-0.5125735357359387,-0.7010844658862807,-0.48932157771479984,0.9150913335574359,-0.48932157771479984,-0.059873687391535715,-0.44302020696238215,-0.08191648177571846,-0.037890347716938104,2.7801310971571085,0.11436040160061789,-0.7489239882266361,3.1084406050615825,-0.6535338132122217,0.9930928138653216,0.7169170935451981,-0.14840553567250234,-0.059873687391535715,0.875822884605927 | 3,039 |
Ion channel transport | 10 | 27 | 2.699514 | 0.006944 | Q9HD20,P51798,Q96PU5,Q93050,P27105,Q9C0H2,P16615,P05023,P51790,Q9Y487 | Processes and pathways | Reactome Pathways | msigdb_reactome | 66,101,70,136,234,138,233,334,219,420 | 334,233,760,1246,1888,234,1541,2632,2194,219,101,959,844,2258,934,471,768,1659,2398,136,70,138,1575,66,1190,420,1342 | 1.0124830674261933,1.3542800263786563,0.2849798960714869,-0.037890347716938104,-0.3284264225634382,1.3542800263786563,-0.17069011224710406,-0.724967851906094,-0.46613729363893336,1.409965539103894,2.273374172038848,0.13588174593938243,0.22140963170165096,-0.48932157771479984,0.15734698889488374,0.6767221488954713,0.2849798960714869,-0.21544405120141735,-0.5592824068345678,1.9483602424077069,2.7002436108444896,1.9309268460754112,-0.17069011224710406,2.748257927082434,0.005899515949245535,0.7768548054179463,-0.059873687391535715 | 3,039 |
Abnormality of pulmonary circulation | 9 | 25 | 2.698344 | 0.006969 | P20674,P00403,P31749,P51798,P03886,O75844,P04062,Q9NZ08,Q14108 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,226,196,101,38,73,171,341,22 | 779,2859,73,505,226,1979,38,171,32,2878,1642,1387,196,2079,1602,101,1356,22,2043,799,339,2942,1666,1114,341 | 0.26384394974348613,-1.0174023844038849,2.668096362263561,0.6160695351919047,1.3728811852532863,-0.3740674450103724,3.275983050297943,1.7190419968762196,3.4554772633739423,-1.067229155753125,-0.21544405120141735,-0.10401912304964674,1.5385430296065519,-0.4199698464474526,-0.1930361462854971,2.273374172038848,-0.08191648177571846,3.7041893683460807,-0.39698574608401843,0.26384394974348613,0.9930928138653216,-1.2955321839628167,-0.21544405120141735,0.04945616636338176,0.9930928138653216 | 3,039 |
Nervous system process | 26 | 96 | 2.696684 | 0.007003 | Q9Y5J9,O60443,Q14108,P17900,Q8TEW0,P50897,Q9BPZ3,O43924,P04062,Q9H6K4,P07686,Q92542,Q13641,Q13432,P31749,O75844,O00264,Q99797,Q9UQB8,P10253,Q99538,O14773,P27361,Q14168,Q9Y6M9,O75695 | Processes and pathways | GO Biological process | msigdb_gobp | 392,267,22,152,408,31,170,42,171,48,55,183,437,64,196,73,327,209,210,218,221,231,237,239,383,122 | 1718,327,1237,231,42,461,267,1976,1680,2558,2116,1122,1636,122,1085,73,542,484,2523,171,2181,2850,1200,1384,1169,55,218,152,1442,1732,1642,237,196,1485,1687,2297,792,2080,1250,3014,2469,1310,31,630,1789,724,1262,2389,745,2390,1177,725,797,932,632,64,2092,437,22,239,1411,2260,1800,2262,1500,2822,2694,1141,2973,534,1698,1031,2573,408,183,2483,2666,2733,1148,221,1034,209,2867,170,1771,1817,2159,48,1866,2933,1675,2830,210,1081,392,383 | -0.2604471495603937,1.0318297557529534,-0.037890347716938104,1.3542800263786563,3.1697059703407153,0.69684344960622,1.2229517085712236,-0.3740674450103724,-0.23791424484342957,-0.6772732957307089,-0.44302020696238215,0.027706804197958748,-0.21544405120141735,2.0866288849685453,0.04945616636338176,2.668096362263561,0.5549779266548395,0.6363354713395758,-0.6535338132122217,1.7190419968762196,-0.46613729363893336,-0.9926088412170806,-0.01596607463826186,-0.10401912304964674,0.005899515949245535,2.859343234867589,1.409965539103894,1.8608535136088946,-0.12618200751855965,-0.2604471495603937,-0.21544405120141735,1.3356392751731447,1.5385430296065519,-0.14840553567250234,-0.23791424484342957,-0.5125735357359387,0.26384394974348613,-0.4199698464474526,-0.037890347716938104,-2.255823209902375,-0.606267828635831,-0.059873687391535715,3.470285289418032,0.4314463011221435,-0.2830431922681599,0.32709103081034985,-0.037890347716938104,-0.5592824068345678,0.3060621463513644,-0.5592824068345678,0.005899515949245535,0.32709103081034985,0.26384394974348613,0.15734698889488374,0.4314463011221435,2.748257927082434,-0.4199698464474526,0.7369433540186023,3.7041893683460807,1.3356392751731447,-0.10401912304964674,-0.48932157771479984,-0.2830431922681599,-0.48932157771479984,-0.14840553567250234,-0.9432583526028255,-0.7729534155941898,0.027706804197958748,-1.477950289982449,0.5753910503793658,-0.23791424484342957,0.09278259830834672,-0.6772732957307089,0.7967405306725779,1.6652764555563804,-0.606267828635831,-0.7489239882266361,-0.8212343386218275,0.027706804197958748,1.409965539103894,0.09278259830834672,1.483667990965456,-1.0174023844038849,1.736891982086496,-0.2604471495603937,-0.2830431922681599,-0.44302020696238215,3.1084406050615825,-0.3057028045175211,-1.2442068622654376,-0.21544405120141735,-0.9432583526028255,1.483667990965456,0.07114797485870293,0.856120860427004,0.875822884605927 | 3,039 |
Protein transporter activity | 7 | 14 | 2.692394 | 0.007094 | Q9HD20,O60830,Q9Y5J9,Q9NS69,Q99595,Q15388,O14925 | Functions | GO Molecular function | msigdb_gomf | 66,3,392,5,9,114,214 | 214,3,2178,862,387,2252,1902,114,1031,9,66,5,853,392 | 1.4284491364966743,5.053064615984644,-0.46613729363893336,0.20011058306743956,0.856120860427004,-0.48932157771479984,-0.3284264225634382,2.120868736002922,0.09278259830834672,4.495028981433672,2.748257927082434,4.964265885140395,0.22140963170165096,0.856120860427004 | 3,039 |
Abnormality of the spleen | 26 | 108 | 2.6883 | 0.007182 | Q14739,Q13510,P16278,P10619,Q15392,P00813,Q14108,P33991,Q9UJS0,P04066,P07602,P04062,P07686,P11166,P21964,P15586,Q9BT22,P31749,Q10713,P14174,P10253,O15118,P51798,Q96AD5,P54802,Q9Y3Z3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,6,16,145,281,20,22,276,164,295,43,171,55,310,317,187,195,196,197,80,218,93,101,240,113,248 | 2648,2458,2330,502,2421,738,93,1382,2115,2558,1197,782,2066,1168,1835,20,1979,171,295,2653,1198,3003,1384,2119,43,55,1927,218,145,310,2463,2685,1014,2686,80,187,16,506,2337,1246,317,1733,3008,2771,463,986,2532,196,276,520,2296,1933,1739,2744,2079,1091,1132,1602,2248,1845,1253,101,1996,1649,113,1491,2935,1548,870,1058,2343,197,682,3010,2393,6,934,1498,22,260,2603,281,2046,768,2402,1807,1459,2314,2942,2481,1562,2639,418,240,1666,439,2576,547,195,2549,341,457,164,444,1874,778,248,1344 | -0.7489239882266361,-0.606267828635831,-0.5358936496388635,0.6160695351919047,-0.5827403002940941,0.3060621463513644,2.35701295367094,-0.10401912304964674,-0.44302020696238215,-0.6772732957307089,-0.01596607463826186,0.26384394974348613,-0.4199698464474526,0.005899515949245535,-0.3057028045175211,3.890193613688759,-0.3740674450103724,1.7190419968762196,1.1470081486218546,-0.7489239882266361,-0.01596607463826186,-2.0250500657604884,-0.10401912304964674,-0.44302020696238215,3.154426526604387,2.859343234867589,-0.35121448743560607,1.409965539103894,1.895958450657215,1.0896107895774603,-0.606267828635831,-0.7729534155941898,0.09278259830834672,-0.7729534155941898,2.5546987479486667,1.5930794075923984,3.9467246428005365,0.6160695351919047,-0.5358936496388635,-0.037890347716938104,1.070393382836239,-0.2604471495603937,-2.1395193234509033,-0.8698150771053541,0.69684344960622,0.11436040160061789,-0.6535338132122217,1.5385430296065519,1.2040279643762803,0.5957548236023519,-0.5125735357359387,-0.35121448743560607,-0.2604471495603937,-0.8454869482570131,-0.4199698464474526,0.04945616636338176,0.027706804197958748,-0.1930361462854971,-0.48932157771479984,-0.3057028045175211,-0.037890347716938104,2.273374172038848,-0.3740674450103724,-0.21544405120141735,2.120868736002922,-0.14840553567250234,-1.2698263697676262,-0.17069011224710406,0.20011058306743956,0.07114797485870293,-0.5358936496388635,1.5385430296065519,0.36899000714620145,-2.1684205196784307,-0.5592824068345678,4.797294388390134,0.15734698889488374,-0.14840553567250234,3.7041893683460807,1.2606762141367405,-0.7010844658862807,1.2040279643762803,-0.39698574608401843,0.2849798960714869,-0.5592824068345678,-0.2830431922681599,-0.12618200751855965,-0.5125735357359387,-1.2955321839628167,-0.606267828635831,-0.17069011224710406,-0.724967851906094,0.7768548054179463,1.3356392751731447,-0.21544405120141735,0.7369433540186023,-0.6772732957307089,0.5549779266548395,1.5567592001978614,-0.6535338132122217,0.9930928138653216,0.7169170935451981,1.7902287843769074,0.7369433540186023,-0.3057028045175211,0.2849798960714869,1.3169587262701798,-0.059873687391535715 | 3,039 |
Abnormal cellular phenotype | 44 | 175 | 2.685646 | 0.007239 | Q14739,O43772,Q13510,P13073,Q70HW3,P09601,P00813,Q14108,P33991,Q9Y2R0,P20674,Q4J6C6,Q9UJS0,P03886,P07602,P04062,Q9BXW9,O75306,Q16134,P40939,Q96CU9,P11166,O43676,P00846,P15586,P21964,Q9NZJ7,P31749,O75844,O43678,Q9UBX3,P14174,Q7LG56,O75503,P00403,P49748,P51798,Q9Y6M9,P23786,O14773,Q86Y39,Q96AD5,Q7KZN9,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,129,6,386,137,13,20,22,276,30,32,414,164,38,43,171,308,182,313,435,61,310,62,63,187,317,457,196,73,445,77,80,212,94,226,228,101,383,108,231,361,240,371,244 | 2648,2458,3030,1381,2330,915,502,231,2980,62,445,129,918,1680,1044,182,1239,94,73,474,2651,1725,2066,1834,505,226,1835,20,63,1979,1383,38,171,1198,43,2335,13,720,2292,310,2685,786,3024,2032,759,2686,2527,386,1987,80,187,3027,812,1887,2687,2033,2796,32,2970,2878,789,317,2125,108,1388,2075,1889,463,2378,2468,2532,2861,2340,196,276,244,2193,2077,1739,435,792,2383,2131,487,1132,1602,228,2881,2198,2248,101,1356,2132,1313,1996,2746,1689,2085,1022,928,1552,1654,1058,725,2912,682,1793,3010,1750,6,934,1498,22,260,1799,1453,2046,995,768,313,2307,1414,1503,1854,414,1804,2308,2509,2897,1807,137,371,212,2973,361,1330,1949,2405,1952,2445,1562,1277,1423,2222,240,1666,61,1510,2887,940,2668,1149,616,308,2226,2808,1625,2107,2163,457,1519,1520,2550,77,164,670,540,981,30,1193,2366,644,737,1344,383 | -0.7489239882266361,-0.606267828635831,-3.4336046535863733,-0.10401912304964674,-0.5358936496388635,0.15734698889488374,0.6160695351919047,1.3542800263786563,-1.5842022719894953,2.7642080742589887,0.7169170935451981,2.0004591255918744,0.15734698889488374,-0.23791424484342957,0.07114797485870293,1.6652764555563804,-0.037890347716938104,2.35701295367094,2.668096362263561,0.6565529155942527,-0.7489239882266361,-0.2604471495603937,-0.4199698464474526,-0.3057028045175211,0.6160695351919047,1.3728811852532863,-0.3057028045175211,3.890193613688759,2.7642080742589887,-0.3740674450103724,-0.10401912304964674,3.275983050297943,1.7190419968762196,-0.01596607463826186,3.154426526604387,-0.5358936496388635,4.030919006514059,0.32709103081034985,-0.5125735357359387,1.0896107895774603,-0.7729534155941898,0.26384394974348613,-2.803971123021496,-0.39698574608401843,0.2849798960714869,-0.7729534155941898,-0.6535338132122217,0.856120860427004,-0.3740674450103724,2.5546987479486667,1.5930794075923984,-3.1613896324023307,0.24265397388246301,-0.3284264225634382,-0.7729534155941898,-0.39698574608401843,-0.9187001949064155,3.4554772633739423,-1.477950289982449,-1.067229155753125,0.26384394974348613,1.070393382836239,-0.44302020696238215,2.154980055528231,-0.10401912304964674,-0.4199698464474526,-0.3284264225634382,0.69684344960622,-0.5592824068345678,-0.606267828635831,-0.6535338132122217,-1.0174023844038849,-0.5358936496388635,1.5385430296065519,1.2040279643762803,1.3169587262701798,-0.46613729363893336,-0.4199698464474526,-0.2604471495603937,0.7369433540186023,0.26384394974348613,-0.5592824068345678,-0.44302020696238215,0.6363354713395758,0.027706804197958748,-0.1930361462854971,1.3728811852532863,-1.067229155753125,-0.46613729363893336,-0.48932157771479984,2.273374172038848,-0.08191648177571846,-0.44302020696238215,-0.059873687391535715,-0.3740674450103724,-0.8454869482570131,-0.23791424484342957,-0.4199698464474526,0.09278259830834672,0.15734698889488374,-0.17069011224710406,-0.21544405120141735,0.07114797485870293,0.32709103081034985,-1.142578020067442,0.36899000714620145,-0.2830431922681599,-2.1684205196784307,-0.2604471495603937,4.797294388390134,0.15734698889488374,-0.14840553567250234,3.7041893683460807,1.2606762141367405,-0.2830431922681599,-0.12618200751855965,-0.39698574608401843,0.11436040160061789,0.2849798960714869,1.0896107895774603,-0.5125735357359387,-0.10401912304964674,-0.14840553567250234,-0.3057028045175211,0.7768548054179463,-0.2830431922681599,-0.5125735357359387,-0.629865496214547,-1.0922636419622016,-0.2830431922681599,1.9309268460754112,0.895479624968376,1.4653001660607239,-1.477950289982449,0.9150913335574359,-0.059873687391535715,-0.35121448743560607,-0.5592824068345678,-0.35121448743560607,-0.5827403002940941,-0.17069011224710406,-0.037890347716938104,-0.10401912304964674,-0.46613729363893336,1.3356392751731447,-0.21544405120141735,2.7801310971571085,-0.14840553567250234,-1.067229155753125,0.15734698889488374,-0.7489239882266361,0.027706804197958748,0.4521617483820871,1.1087855671016753,-0.46613729363893336,-0.9187001949064155,-0.1930361462854971,-0.4199698464474526,-0.44302020696238215,0.7169170935451981,-0.14840553567250234,-0.14840553567250234,-0.6535338132122217,2.603467193814167,1.7902287843769074,0.3898607435766084,0.5753910503793658,0.13588174593938243,3.5439873534993933,0.005899515949245535,-0.5358936496388635,0.4314463011221435,0.32709103081034985,-0.059873687391535715,0.875822884605927 | 3,039 |
Cardiac muscle contraction | 7 | 17 | 2.685413 | 0.007244 | P20674,P00403,P16615,P05023,P14406,Q9UDW1,O14949 | Processes and pathways | KEGG Pathways | msigdb_kegg | 32,226,233,334,146,54,56 | 56,226,334,1594,1243,740,386,146,2631,841,233,32,699,2379,959,1260,54 | 2.843554170946297,1.3728811852532863,1.0124830674261933,-0.1930361462854971,-0.037890347716938104,0.3060621463513644,0.856120860427004,1.895958450657215,-0.724967851906094,0.22140963170165096,1.3542800263786563,3.4554772633739423,0.34806687646145595,-0.5592824068345678,0.13588174593938243,-0.037890347716938104,2.890842077222198 | 3,039 |
Intrinsic component of plasma membrane | 39 | 70 | 2.683128 | 0.007294 | Q9UIQ6,P36551,Q9Y289,Q96QD8,O60637,O43657,Q8N2K0,P35613,Q02978,Q9UJS0,P53985,O15498,Q07954,Q9H2J7,Q92542,Q13641,P11166,O96005,O76062,Q8NAN2,O00264,Q8NBJ4,P20645,Q9H1Z9,P05023,Q99797,Q9UNN8,O00560,P51790,O15118,Q9UNK0,Q8WTV0,Q9NR28,Q9BTU6,P27105,P16615,O95864,Q9Y4G8,P51572 | Localization | GO Cellular component | msigdb_gocc | 143,520,540,270,17,21,407,277,529,164,412,549,555,442,183,437,310,194,324,571,327,204,583,78,334,209,473,467,219,93,620,96,619,363,234,233,243,255,251 | 1119,327,467,1040,1632,93,549,21,17,324,243,194,1383,1087,334,757,1200,864,675,310,607,787,759,233,1838,760,583,234,890,1248,277,520,2654,251,219,412,959,2784,1653,928,529,555,765,1410,437,2262,900,903,1559,407,571,204,1183,96,183,270,209,363,3038,78,442,2161,619,2058,143,164,620,473,540,255 | 0.027706804197958748,1.0318297557529534,0.6767221488954713,0.07114797485870293,-0.21544405120141735,2.35701295367094,0.5345151608497005,3.7474278391803297,3.918499645749727,1.0511331158891664,1.3169587262701798,1.5567592001978614,-0.10401912304964674,0.04945616636338176,1.0124830674261933,0.2849798960714869,-0.01596607463826186,0.20011058306743956,0.36899000714620145,1.0896107895774603,0.4521617483820871,0.26384394974348613,0.2849798960714869,1.3542800263786563,-0.3057028045175211,0.2849798960714869,0.4934395229159375,1.3542800263786563,0.17875648445362774,-0.037890347716938104,1.2040279643762803,0.5957548236023519,-0.7489239882266361,1.2982381726059844,1.409965539103894,0.7768548054179463,0.13588174593938243,-0.8942192990435678,-0.21544405120141735,0.15734698889488374,0.5753910503793658,0.5345151608497005,0.2849798960714869,-0.10401912304964674,0.7369433540186023,-0.48932157771479984,0.17875648445362774,0.17875648445362774,-0.17069011224710406,0.7967405306725779,0.5140024586389151,1.5019976151465506,0.005899515949245535,2.3236489114327066,1.6652764555563804,1.2229517085712236,1.483667990965456,0.9150913335574359,-14.138461661029716,2.570983381448192,0.7369433540186023,-0.44302020696238215,0.4521617483820871,-0.39698574608401843,1.9134596354218771,1.7902287843769074,0.4521617483820871,0.6767221488954713,0.5753910503793658,1.2982381726059844 | 3,039 |
Peptidase activity | 39 | 108 | 2.678406 | 0.007397 | Q15005,P49721,O75976,P36551,Q9UIQ6,P67812,P10619,Q9H3G5,Q4J6C6,Q8TCT9,P42785,P45974,Q92542,Q969V3,Q8TCT8,P55786,P09960,P55210,Q9H300,Q9BT78,P42892,Q10713,Q9HB40,Q93009,Q92820,O75844,Q16740,P28070,P20618,Q99797,Q9NZ08,P60900,Q7Z2K6,Q99538,P28072,Q96K76,O14773,P28074,P14735 | Functions | GO Molecular function | msigdb_gomf | 507,130,385,520,143,141,145,34,414,559,47,553,183,315,188,60,192,567,321,455,68,197,71,325,453,73,586,463,207,209,341,469,220,221,224,357,231,374,249 | 673,1293,231,717,1433,916,2333,73,385,1296,1724,2067,1383,1926,192,145,2686,1299,249,2852,207,699,2466,463,224,374,2494,2532,2242,520,1786,47,68,553,957,924,130,3000,1995,1846,1208,2499,630,1399,567,60,469,648,141,3021,1099,197,2864,682,1266,1061,2659,507,586,414,2005,728,901,604,1614,2309,1761,1369,220,2097,828,188,559,183,453,1562,971,2446,325,315,2449,1859,357,1812,830,753,2756,221,209,1111,455,974,321,34,2106,2452,1284,71,852,944,1712,2581,341,2674,143,1524,644,2921 | 0.36899000714620145,-0.059873687391535715,1.3542800263786563,0.32709103081034985,-0.12618200751855965,0.15734698889488374,-0.5358936496388635,2.668096362263561,0.856120860427004,-0.059873687391535715,-0.2604471495603937,-0.4199698464474526,-0.10401912304964674,-0.35121448743560607,1.574937930723592,1.895958450657215,-0.7729534155941898,-0.059873687391535715,1.2982381726059844,-0.9926088412170806,1.483667990965456,0.34806687646145595,-0.606267828635831,0.69684344960622,1.3914429554854009,0.875822884605927,-0.629865496214547,-0.6535338132122217,-0.48932157771479984,0.5957548236023519,-0.2830431922681599,3.123793940195311,2.716275809025029,0.5345151608497005,0.13588174593938243,0.15734698889488374,2.0004591255918744,-1.8566367899690628,-0.3740674450103724,-0.3057028045175211,-0.01596607463826186,-0.629865496214547,0.4314463011221435,-0.10401912304964674,0.5140024586389151,2.7801310971571085,0.6767221488954713,0.4106794033765102,1.9134596354218771,-2.67843410440958,0.04945616636338176,1.5385430296065519,-1.0174023844038849,0.36899000714620145,-0.037890347716938104,0.07114797485870293,-0.7489239882266361,0.6160695351919047,0.4934395229159375,0.7768548054179463,-0.3740674450103724,0.32709103081034985,0.17875648445362774,0.47282605375654435,-0.1930361462854971,-0.5125735357359387,-0.2604471495603937,-0.08191648177571846,1.409965539103894,-0.4199698464474526,0.24265397388246301,1.5930794075923984,0.5345151608497005,1.6652764555563804,0.7169170935451981,-0.17069011224710406,0.13588174593938243,-0.5827403002940941,1.0511331158891664,1.0896107895774603,-0.5827403002940941,-0.3057028045175211,0.9346582601951924,-0.2830431922681599,0.24265397388246301,0.3060621463513644,-0.8454869482570131,1.409965539103894,1.483667990965456,0.04945616636338176,0.7169170935451981,0.13588174593938243,1.070393382836239,3.440646503624223,-0.4199698464474526,-0.5827403002940941,-0.037890347716938104,2.7002436108444896,0.22140963170165096,0.15734698889488374,-0.23791424484342957,-0.6772732957307089,0.9930928138653216,-0.7489239882266361,1.9134596354218771,-0.14840553567250234,0.4314463011221435,-1.167859218190506 | 3,039 |
Steroid metabolism | 11 | 27 | 2.674459 | 0.007485 | Q9H2C2,Q14739,Q15800,P37268,Q15125,P04062,Q15392,Q16850,P14324,Q06520,O15118 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 163,260,264,236,10,171,281,52,118,88,93 | 93,324,887,1439,171,118,2125,236,2385,413,1998,3002,1058,88,2658,260,10,1453,281,1026,264,52,2668,163,1626,2327,2582 | 2.35701295367094,1.0511331158891664,0.17875648445362774,-0.12618200751855965,1.7190419968762196,2.1037649504595,-0.44302020696238215,1.3542800263786563,-0.5592824068345678,0.7768548054179463,-0.3740674450103724,-1.9967112632049284,0.07114797485870293,2.4068330171621493,-0.7489239882266361,1.2606762141367405,4.2383322485299875,-0.12618200751855965,1.2040279643762803,0.09278259830834672,1.2418343865431385,2.9847119746833544,-0.7489239882266361,1.7902287843769074,-0.1930361462854971,-0.5125735357359387,-0.6772732957307089 | 3,039 |
Chemical homeostasis | 47 | 171 | 2.674187 | 0.007491 | Q92504,Q16739,Q93050,Q7L0J3,P09601,P30519,O15260,Q9Y487,P50897,Q96A33,P54646,P53985,P04062,Q9HC07,P42785,P62995,Q8N511,Q96CP7,Q9P035,P07686,Q9Y5X3,Q16531,Q9HD20,Q9UM00,P31749,Q15067,Q96PU5,P05023,O15254,Q8N5M9,Q5BJF2,Q8NEW0,P51790,P34913,O75503,O15118,Q8WTV0,O75880,P30536,P16615,P27361,Q96AD5,P52789,O76024,Q9HCL2,P51572,Q9NQC3 | Processes and pathways | GO Biological process | msigdb_gobp | 131,265,136,395,13,19,27,420,31,418,413,412,171,174,47,423,50,178,443,55,458,319,66,323,196,449,70,334,85,344,89,345,219,468,94,93,96,474,235,233,237,240,489,484,515,251,127 | 1719,2458,656,1194,2421,1237,93,1474,85,27,1976,919,1043,94,474,2891,484,2523,782,1590,1167,2704,1638,1383,171,2181,1593,334,698,1123,1384,55,1981,1781,1298,13,1536,2998,1984,865,1886,1538,233,741,2239,2839,1731,2965,2337,760,1124,2706,237,1483,2771,1891,2532,19,235,1541,196,468,2194,1739,2079,47,2080,1132,1647,1251,31,896,1489,251,219,2690,489,412,413,959,2784,844,961,1939,554,423,2432,1262,745,2390,1177,545,797,820,632,3036,2092,1658,449,612,1800,2262,768,319,2141,265,685,770,89,846,1760,2967,395,2611,1910,1330,50,344,633,801,345,710,96,572,131,136,418,240,1666,178,2929,2665,70,1334,973,2756,2915,1623,775,2919,2055,2698,2808,2159,833,1575,668,174,514,515,66,2989,1517,127,2058,836,443,2327,2416,1190,1290,912,323,1292,420,644,458,2584,1008,1118,3006 | -0.2604471495603937,-0.606267828635831,0.3898607435766084,-0.01596607463826186,-0.5827403002940941,-0.037890347716938104,2.35701295367094,-0.14840553567250234,2.472843405594802,3.6025482837872342,-0.3740674450103724,0.15734698889488374,0.07114797485870293,2.35701295367094,0.6565529155942527,-1.0922636419622016,0.6363354713395758,-0.6535338132122217,0.26384394974348613,-0.1930361462854971,0.005899515949245535,-0.7970566811673792,-0.21544405120141735,-0.10401912304964674,1.7190419968762196,-0.46613729363893336,-0.1930361462854971,1.0124830674261933,0.34806687646145595,0.027706804197958748,-0.10401912304964674,2.859343234867589,-0.3740674450103724,-0.2830431922681599,-0.059873687391535715,4.030919006514059,-0.17069011224710406,-1.801344384543344,-0.3740674450103724,0.20011058306743956,-0.3284264225634382,-0.17069011224710406,1.3542800263786563,0.3060621463513644,-0.48932157771479984,-0.9678943672344994,-0.2604471495603937,-1.451619920580497,-0.5358936496388635,0.2849798960714869,0.027706804197958748,-0.7970566811673792,1.3356392751731447,-0.14840553567250234,-0.8698150771053541,-0.3284264225634382,-0.6535338132122217,3.9043567944213824,1.3542800263786563,-0.17069011224710406,1.5385430296065519,0.6767221488954713,-0.46613729363893336,-0.2604471495603937,-0.4199698464474526,3.123793940195311,-0.4199698464474526,0.027706804197958748,-0.21544405120141735,-0.037890347716938104,3.470285289418032,0.17875648445362774,-0.14840553567250234,1.2982381726059844,1.409965539103894,-0.7729534155941898,0.6363354713395758,0.7768548054179463,0.7768548054179463,0.13588174593938243,-0.8942192990435678,0.22140963170165096,0.13588174593938243,-0.35121448743560607,0.5345151608497005,0.7569225018513692,-0.5827403002940941,-0.037890347716938104,0.3060621463513644,-0.5592824068345678,0.005899515949245535,0.5549779266548395,0.26384394974348613,0.24265397388246301,0.4314463011221435,-4.404868850320807,-0.4199698464474526,-0.21544405120141735,0.7169170935451981,0.4521617483820871,-0.2830431922681599,-0.48932157771479984,0.2849798960714869,1.070393382836239,-0.44302020696238215,1.2418343865431385,0.36899000714620145,0.2849798960714869,2.4068330171621493,0.22140963170165096,-0.2604471495603937,-1.451619920580497,0.8363732981403815,-0.7010844658862807,-0.3284264225634382,-0.059873687391535715,3.0312996064863214,0.9736587559602312,0.4314463011221435,0.26384394974348613,0.9736587559602312,0.34806687646145595,2.3236489114327066,0.5140024586389151,2.0004591255918744,1.9483602424077069,0.7768548054179463,1.3356392751731447,-0.21544405120141735,1.6832344093740115,-1.2186729608033915,-0.7489239882266361,2.7002436108444896,-0.059873687391535715,0.13588174593938243,-0.8454869482570131,-1.142578020067442,-0.1930361462854971,0.2849798960714869,-1.167859218190506,-0.39698574608401843,-0.7729534155941898,-0.9187001949064155,-0.44302020696238215,0.24265397388246301,-0.17069011224710406,0.3898607435766084,1.7190419968762196,0.6160695351919047,0.6160695351919047,2.748257927082434,-1.719172153536557,-0.14840553567250234,2.0350255192397007,-0.39698574608401843,0.24265397388246301,0.7369433540186023,-0.5125735357359387,-0.5592824068345678,0.005899515949245535,-0.037890347716938104,0.17875648445362774,1.070393382836239,-0.037890347716938104,0.7768548054179463,0.4314463011221435,0.7169170935451981,-0.6772732957307089,0.11436040160061789,0.04945616636338176,-2.0820597615696625 | 3,039 |
Oxidoreductase activity | 58 | 224 | 2.672821 | 0.007522 | Q9NVH6,Q6NUM9,Q14739,P13073,Q15800,P00374,P09601,Q9H7Z7,Q15392,P14406,P30519,Q14534,Q9H9P8,Q9UHG3,Q8N4Q0,P20674,Q6ZRP7,O43169,P03886,Q8N0U8,Q6YN16,Q9BY49,Q53GQ0,Q14914,Q16850,O00116,Q9UDW1,O75306,P16435,Q16134,Q9NRG7,Q96CU9,P40939,O43676,O76062,Q15067,O43678,O95831,Q8NBM8,Q7LG56,Q8NBX0,O15254,Q99536,Q06136,P00403,P49748,Q9Y6M9,Q13423,P51648,O95168,P13674,Q7KZN9,Q96LJ7,O95864,O00625,P05091,Q3SXM5,P61457 | Functions | GO Molecular function | msigdb_gomf | 128,258,260,386,264,393,13,271,281,146,19,148,156,29,158,32,416,35,38,41,297,431,427,177,52,181,54,182,184,313,190,61,435,62,324,449,445,74,340,212,84,85,217,349,226,228,383,102,104,232,360,371,119,243,116,117,125,377 | 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| 3,039 |
Primary mitochondrial disease | 25 | 83 | 2.671626 | 0.007548 | P13073,Q70HW3,Q9Y276,Q96IX5,Q5XKP0,Q9Y2R0,P20674,P03886,Q8NFF5,O75306,O14949,Q96CU9,O43676,P00846,O43678,O95831,Q9UBX3,O60313,Q99797,Q7LG56,Q6DKK2,P00403,Q86Y39,Q7KZN9,Q9Y6M9 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 386,137,144,399,406,30,32,38,429,182,56,61,62,63,445,74,77,461,209,212,338,226,361,371,383 | 3030,915,56,62,445,461,1044,182,1239,2118,474,2651,74,226,63,38,2335,1243,2184,759,386,2631,2033,32,699,1387,2378,2340,2383,2131,795,2881,2132,1313,2746,2501,2533,2135,2089,2307,651,1804,996,1324,2308,406,338,686,137,371,2609,212,361,2477,1330,429,1146,2405,2222,61,399,940,209,2720,1149,616,1468,2226,1625,1230,1871,1519,1520,2550,77,144,30,1922,2553,2027,1193,2795,383 | -3.4336046535863733,0.15734698889488374,2.843554170946297,2.7642080742589887,0.7169170935451981,0.69684344960622,0.07114797485870293,1.6652764555563804,-0.037890347716938104,-0.44302020696238215,0.6565529155942527,-0.7489239882266361,2.651981080000916,1.3728811852532863,2.7642080742589887,3.275983050297943,-0.5358936496388635,-0.037890347716938104,-0.46613729363893336,0.2849798960714869,0.856120860427004,-0.724967851906094,-0.39698574608401843,3.4554772633739423,0.34806687646145595,-0.10401912304964674,-0.5592824068345678,-0.5358936496388635,-0.5592824068345678,-0.44302020696238215,0.26384394974348613,-1.067229155753125,-0.44302020696238215,-0.059873687391535715,-0.8454869482570131,-0.629865496214547,-0.6535338132122217,-0.44302020696238215,-0.4199698464474526,-0.5125735357359387,0.4106794033765102,-0.2830431922681599,0.11436040160061789,-0.059873687391535715,-0.5125735357359387,0.7967405306725779,0.9930928138653216,0.36899000714620145,1.9309268460754112,0.895479624968376,-0.7010844658862807,1.4653001660607239,0.9150913335574359,-0.606267828635831,-0.059873687391535715,0.7569225018513692,0.027706804197958748,-0.5592824068345678,-0.46613729363893336,2.7801310971571085,0.8363732981403815,0.15734698889488374,1.483667990965456,-0.7970566811673792,0.027706804197958748,0.4521617483820871,-0.12618200751855965,-0.46613729363893336,-0.1930361462854971,-0.01596607463826186,-0.3057028045175211,-0.14840553567250234,-0.14840553567250234,-0.6535338132122217,2.603467193814167,1.9134596354218771,3.5439873534993933,-0.3284264225634382,-0.6535338132122217,-0.3740674450103724,0.005899515949245535,-0.8942192990435678,0.875822884605927 | 3,039 |
Behavior | 21 | 72 | 2.667904 | 0.007633 | Q8N2K0,P17900,Q96RL7,P50897,P53985,Q9BPZ3,P04062,P07686,Q92542,Q13641,P31749,O00264,O75844,P10253,P51790,Q99538,O15118,P30536,P54802,O76024,P50416 | Processes and pathways | GO Biological process | msigdb_gobp | 407,152,547,31,412,170,171,55,183,437,196,327,73,218,219,221,93,235,113,484,245 | 1718,327,93,2702,73,542,484,2523,1592,171,1297,2181,1198,1200,1351,1384,55,1478,1535,218,2852,152,1442,1642,1389,235,196,1687,2297,1739,792,2080,1250,1207,245,31,219,412,113,1789,2389,745,2344,1177,1497,2092,437,1411,992,965,2262,2694,1615,2973,800,752,407,1031,183,2015,2666,1148,547,1860,2756,221,1034,170,2159,2413,1866,1236 | -0.2604471495603937,1.0318297557529534,2.35701295367094,-0.7970566811673792,2.668096362263561,0.5549779266548395,0.6363354713395758,-0.6535338132122217,-0.1930361462854971,1.7190419968762196,-0.059873687391535715,-0.46613729363893336,-0.01596607463826186,-0.01596607463826186,-0.08191648177571846,-0.10401912304964674,2.859343234867589,-0.14840553567250234,-0.17069011224710406,1.409965539103894,-0.9926088412170806,1.8608535136088946,-0.12618200751855965,-0.21544405120141735,-0.10401912304964674,1.3542800263786563,1.5385430296065519,-0.23791424484342957,-0.5125735357359387,-0.2604471495603937,0.26384394974348613,-0.4199698464474526,-0.037890347716938104,-0.01596607463826186,1.3169587262701798,3.470285289418032,1.409965539103894,0.7768548054179463,2.120868736002922,-0.2830431922681599,-0.5592824068345678,0.3060621463513644,-0.5358936496388635,0.005899515949245535,-0.14840553567250234,-0.4199698464474526,0.7369433540186023,-0.10401912304964674,0.11436040160061789,0.13588174593938243,-0.48932157771479984,-0.7729534155941898,-0.1930361462854971,-1.477950289982449,0.26384394974348613,0.3060621463513644,0.7967405306725779,0.09278259830834672,1.6652764555563804,-0.3740674450103724,-0.7489239882266361,0.027706804197958748,0.5549779266548395,-0.3057028045175211,-0.8454869482570131,1.409965539103894,0.09278259830834672,1.736891982086496,-0.44302020696238215,-0.5592824068345678,-0.3057028045175211,-0.01596607463826186 | 3,039 |
Organic anion transport | 28 | 45 | 2.662603 | 0.007754 | P05141,P12235,Q7L0J3,Q6NUK1,Q9Y289,Q96QD8,Q02978,O75915,Q9UJS0,P53985,P07602,Q14728,Q9H2J7,P11166,Q9NZJ7,Q9H936,Q8TB61,Q9UBX3,O60831,P14174,P12236,P53007,O43808,Q9HC21,Q15041,Q9H9B4,Q9H2D1,Q9Y619 | Processes and pathways | GO Biological process | msigdb_gobp | 757,759,395,799,540,270,529,542,164,412,43,426,442,310,457,456,72,77,582,80,721,723,353,618,749,641,120,382 | 1237,353,582,1085,542,2704,1780,757,1200,43,783,310,759,721,80,1642,986,2654,723,412,2784,529,426,749,2260,900,799,1855,395,72,875,270,120,442,456,641,618,1517,457,77,2582,164,540,382,3006 | -0.037890347716938104,0.9346582601951924,0.4934395229159375,0.04945616636338176,0.5549779266548395,-0.7970566811673792,-0.2830431922681599,0.2849798960714869,-0.01596607463826186,3.154426526604387,0.26384394974348613,1.0896107895774603,0.2849798960714869,0.32709103081034985,2.5546987479486667,-0.21544405120141735,0.11436040160061789,-0.7489239882266361,0.32709103081034985,0.7768548054179463,-0.8942192990435678,0.5753910503793658,0.7569225018513692,0.3060621463513644,-0.48932157771479984,0.17875648445362774,0.26384394974348613,-0.3057028045175211,0.8363732981403815,2.6841838337725745,0.20011058306743956,1.2229517085712236,2.1037649504595,0.7369433540186023,0.7169170935451981,0.4314463011221435,0.4521617483820871,-0.14840553567250234,0.7169170935451981,2.603467193814167,-0.6772732957307089,1.7902287843769074,0.5753910503793658,0.875822884605927,-2.0820597615696625 | 3,039 |
Bruising susceptibility | 8 | 24 | 2.655776 | 0.007913 | Q13126,P51798,P38435,Q8NCH0,P04062,P49257,Q9NWM8,Q14108 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 229,101,263,75,171,269,242,22 | 1120,171,2119,840,1731,2878,1304,1249,263,1739,269,1602,101,2254,2255,229,22,2693,1800,1140,75,308,242,2676 | 0.027706804197958748,1.7190419968762196,-0.44302020696238215,0.22140963170165096,-0.2604471495603937,-1.067229155753125,-0.059873687391535715,-0.037890347716938104,1.2418343865431385,-0.2604471495603937,1.2229517085712236,-0.1930361462854971,2.273374172038848,-0.48932157771479984,-0.48932157771479984,1.3728811852532863,3.7041893683460807,-0.7729534155941898,-0.2830431922681599,0.027706804197958748,2.651981080000916,1.1087855671016753,1.3356392751731447,-0.7489239882266361 | 3,039 |
serine protease | 8 | 17 | 2.654737 | 0.007937 | Q9H300,Q9H3G5,Q9HB40,O14773,P67812,P42785,P10619,Q8N2K0 | Functions | Panther Protein class | panther_protein_class | 321,34,71,231,141,47,145,407 | 231,145,2336,1299,2532,1786,47,957,141,586,414,407,1952,321,34,71,1627 | 1.3542800263786563,1.895958450657215,-0.5358936496388635,-0.059873687391535715,-0.6535338132122217,-0.2830431922681599,3.123793940195311,0.13588174593938243,1.9134596354218771,0.4934395229159375,0.7768548054179463,0.7967405306725779,-0.35121448743560607,1.070393382836239,3.440646503624223,2.7002436108444896,-0.1930361462854971 | 3,039 |
Visual loss | 15 | 46 | 2.652304 | 0.007994 | P00403,P31749,Q10713,P03886,P51798,Q9NZJ7,P07602,O14773,P48449,O75503,O75306,P53701,P40939,P00846,P50897 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 226,196,197,38,101,457,43,231,278,94,182,343,435,63,31 | 2938,2419,1120,1381,231,1475,461,182,2333,94,1197,2372,226,2291,63,38,2850,1087,43,2493,2526,2687,1642,196,743,1932,435,278,31,1253,101,2978,343,2746,1057,197,1408,2820,1799,1505,731,732,1277,1226,2668,457 | -1.2955321839628167,-0.5827403002940941,0.027706804197958748,-0.10401912304964674,1.3542800263786563,-0.14840553567250234,0.69684344960622,1.6652764555563804,-0.5358936496388635,2.35701295367094,-0.01596607463826186,-0.5592824068345678,1.3728811852532863,-0.5125735357359387,2.7642080742589887,3.275983050297943,-0.9926088412170806,0.04945616636338176,3.154426526604387,-0.629865496214547,-0.6535338132122217,-0.7729534155941898,-0.21544405120141735,1.5385430296065519,0.3060621463513644,-0.35121448743560607,0.7369433540186023,1.2040279643762803,3.470285289418032,-0.037890347716938104,2.273374172038848,-1.5308885852988285,0.9736587559602312,-0.8454869482570131,0.07114797485870293,1.5385430296065519,-0.10401912304964674,-0.9432583526028255,-0.2830431922681599,-0.14840553567250234,0.32709103081034985,0.32709103081034985,-0.037890347716938104,-0.01596607463826186,-0.7489239882266361,0.7169170935451981 | 3,039 |
Abnormality of extrapyramidal motor function | 18 | 70 | 2.650951 | 0.008027 | P35637,P98175,O14949,P06865,Q9Y4P3,P07602,P04062,P16278,Q9H6K4,Q6DKK2,Q7LG56,Q9Y3Z3,P07686,P17900,Q9H9P8,P11166,P61457,Q99720 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 244,290,56,100,261,43,171,16,48,338,212,248,55,152,156,310,377,97 | 56,1044,1122,862,1592,171,1594,100,43,55,784,310,626,759,16,2839,152,1887,2796,1785,2377,2379,1737,1391,244,1091,2080,629,2746,1936,2085,1491,377,2205,290,871,2343,2344,725,1060,1793,1411,1322,1804,338,2979,2694,2570,212,399,1148,547,2756,97,2915,693,908,48,156,2161,457,716,2699,1582,1081,694,2232,248,261,644 | 2.843554170946297,0.07114797485870293,0.027706804197958748,0.20011058306743956,-0.1930361462854971,1.7190419968762196,-0.1930361462854971,2.273374172038848,3.154426526604387,2.859343234867589,0.26384394974348613,1.0896107895774603,0.4314463011221435,0.2849798960714869,3.9467246428005365,-0.9678943672344994,1.8608535136088946,-0.3284264225634382,-0.9187001949064155,-0.2830431922681599,-0.5592824068345678,-0.5592824068345678,-0.2604471495603937,-0.10401912304964674,1.3169587262701798,0.04945616636338176,-0.4199698464474526,0.4314463011221435,-0.8454869482570131,-0.35121448743560607,-0.4199698464474526,-0.14840553567250234,0.875822884605927,-0.46613729363893336,1.166056404831489,0.20011058306743956,-0.5358936496388635,-0.5358936496388635,0.32709103081034985,0.07114797485870293,-0.2830431922681599,-0.10401912304964674,-0.059873687391535715,-0.2830431922681599,0.9930928138653216,-1.557498100569569,-0.7729534155941898,-0.6772732957307089,1.4653001660607239,0.8363732981403815,0.027706804197958748,0.5549779266548395,-0.8454869482570131,2.3236489114327066,-1.142578020067442,0.36899000714620145,0.17875648445362774,3.1084406050615825,1.843249435681901,-0.44302020696238215,0.7169170935451981,0.34806687646145595,-0.7729534155941898,-0.17069011224710406,0.07114797485870293,0.36899000714620145,-0.46613729363893336,1.3169587262701798,1.2606762141367405,0.4314463011221435 | 3,039 |
Optic disc pallor | 17 | 47 | 2.644839 | 0.008173 | O96000,Q9Y6M9,Q10713,P03886,P51798,O95831,Q9H061,Q8WWV3,Q86Y39,O60313,Q9H6K4,O75306,Q9UG56,Q96S66,Q96CU9,O43676,P00846 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 505,383,197,38,101,74,12,494,361,461,48,182,517,410,61,62,63 | 3030,1381,502,738,1721,62,1587,461,1044,182,2333,1239,2680,2372,74,505,63,38,1087,2186,2337,2033,984,2378,2881,101,2935,1058,197,2608,361,827,1330,1463,494,2150,1276,61,410,2360,12,908,48,1519,517,644,383 | -3.4336046535863733,-0.10401912304964674,0.6160695351919047,0.3060621463513644,-0.2604471495603937,2.7642080742589887,-0.1930361462854971,0.69684344960622,0.07114797485870293,1.6652764555563804,-0.5358936496388635,-0.037890347716938104,-0.7729534155941898,-0.5592824068345678,2.651981080000916,0.6160695351919047,2.7642080742589887,3.275983050297943,0.04945616636338176,-0.46613729363893336,-0.5358936496388635,-0.39698574608401843,0.11436040160061789,-0.5592824068345678,-1.067229155753125,2.273374172038848,-1.2698263697676262,0.07114797485870293,1.5385430296065519,-0.7010844658862807,0.9150913335574359,0.24265397388246301,-0.059873687391535715,-0.12618200751855965,0.6363354713395758,-0.44302020696238215,-0.037890347716938104,2.7801310971571085,0.7967405306725779,-0.5358936496388635,4.058825415756852,0.17875648445362774,3.1084406050615825,-0.14840553567250234,0.6160695351919047,0.4314463011221435,0.875822884605927 | 3,039 |
Cherry red spot of the macula | 6 | 9 | 2.642786 | 0.008223 | P06865,Q13510,P07602,P16278,P10619,P07686 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 100,6,43,16,145,55 | 100,43,55,145,2186,16,152,6,457 | 2.273374172038848,3.154426526604387,2.859343234867589,1.895958450657215,-0.46613729363893336,3.9467246428005365,1.8608535136088946,4.797294388390134,0.7169170935451981 | 3,039 |
Sterol metabolism | 10 | 25 | 2.640858 | 0.00827 | Q9H2C2,Q14739,Q15800,P37268,Q15125,P04062,Q15392,Q16850,P14324,O15118 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 163,260,264,236,10,171,281,52,118,93 | 93,324,887,1439,171,118,2125,236,2385,413,1998,3002,1058,2658,260,10,1453,281,1026,264,52,163,1626,2327,2582 | 2.35701295367094,1.0511331158891664,0.17875648445362774,-0.12618200751855965,1.7190419968762196,2.1037649504595,-0.44302020696238215,1.3542800263786563,-0.5592824068345678,0.7768548054179463,-0.3740674450103724,-1.9967112632049284,0.07114797485870293,-0.7489239882266361,1.2606762141367405,4.2383322485299875,-0.12618200751855965,1.2040279643762803,0.09278259830834672,1.2418343865431385,2.9847119746833544,1.7902287843769074,-0.1930361462854971,-0.5125735357359387,-0.6772732957307089 | 3,039 |
Steroid biosynthesis | 7 | 11 | 2.639427 | 0.008305 | Q15800,P37268,Q15125,Q15392,Q16850,Q14534,P48449 | Processes and pathways | KEGG Pathways | msigdb_kegg | 264,236,10,281,52,148,278 | 324,236,1933,278,148,10,281,1026,264,52,1626 | 1.0511331158891664,1.3542800263786563,-0.35121448743560607,1.2040279643762803,1.895958450657215,4.2383322485299875,1.2040279643762803,0.09278259830834672,1.2418343865431385,2.9847119746833544,-0.1930361462854971 | 3,039 |
Dyspnea | 18 | 90 | 2.638772 | 0.008321 | P06280,Q9UHX1,P49748,P03886,Q13510,Q92804,O75844,O95831,P07602,P23786,P04350,P04062,Q96AD5,Q7LG56,O75306,Q15165,P10253,P00846 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 191,133,228,38,6,201,73,74,43,108,167,171,240,212,182,57,218,63 | 1829,2114,1382,182,1832,73,1590,2066,74,1439,63,1979,38,171,167,191,2119,43,1980,1385,2184,785,218,840,3024,759,1987,2374,3027,2072,1246,1733,2426,108,1304,244,2381,1393,2077,1739,1092,487,3014,228,2976,1252,677,1356,723,1313,2250,343,2746,2085,1359,1651,989,1790,928,871,1793,2800,6,1498,1411,2043,2693,2349,1800,57,313,1140,212,732,201,2446,1423,938,2222,240,1666,1767,1149,2808,2159,457,133,1081,1676,382 | -0.3057028045175211,-0.44302020696238215,-0.10401912304964674,1.6652764555563804,-0.3057028045175211,2.668096362263561,-0.1930361462854971,-0.4199698464474526,2.651981080000916,-0.12618200751855965,2.7642080742589887,-0.3740674450103724,3.275983050297943,1.7190419968762196,1.736891982086496,1.574937930723592,-0.44302020696238215,3.154426526604387,-0.3740674450103724,-0.10401912304964674,-0.46613729363893336,0.26384394974348613,1.409965539103894,0.22140963170165096,-2.803971123021496,0.2849798960714869,-0.3740674450103724,-0.5592824068345678,-3.1613896324023307,-0.4199698464474526,-0.037890347716938104,-0.2604471495603937,-0.5827403002940941,2.154980055528231,-0.059873687391535715,1.3169587262701798,-0.5592824068345678,-0.10401912304964674,-0.4199698464474526,-0.2604471495603937,0.04945616636338176,0.6363354713395758,-2.255823209902375,1.3728811852532863,-1.5043729151258898,-0.037890347716938104,0.36899000714620145,-0.08191648177571846,0.32709103081034985,-0.059873687391535715,-0.48932157771479984,0.9736587559602312,-0.8454869482570131,-0.4199698464474526,-0.08191648177571846,-0.21544405120141735,0.11436040160061789,-0.2830431922681599,0.15734698889488374,0.20011058306743956,-0.2830431922681599,-0.9187001949064155,4.797294388390134,-0.14840553567250234,-0.10401912304964674,-0.39698574608401843,-0.7729534155941898,-0.5358936496388635,-0.2830431922681599,2.843554170946297,1.0896107895774603,0.027706804197958748,1.4653001660607239,0.32709103081034985,1.5202892310550606,-0.5827403002940941,-0.10401912304964674,0.15734698889488374,-0.46613729363893336,1.3356392751731447,-0.21544405120141735,-0.2604471495603937,0.027706804197958748,-0.9187001949064155,-0.44302020696238215,0.7169170935451981,2.0004591255918744,0.07114797485870293,-0.21544405120141735,0.875822884605927 | 3,039 |
Metalloprotease | 9 | 27 | 2.633263 | 0.008457 | P09960,P42892,O75844,Q9UIQ6,Q99797,Q9NZ08,Q7Z2K6,P55786,P14735 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 192,68,73,143,209,341,220,60,249 | 1293,916,2333,73,385,2067,192,2686,249,68,1208,60,728,1614,220,971,1812,830,209,974,2106,852,944,2581,341,143,644 | -0.059873687391535715,0.15734698889488374,-0.5358936496388635,2.668096362263561,0.856120860427004,-0.4199698464474526,1.574937930723592,-0.7729534155941898,1.2982381726059844,2.716275809025029,-0.01596607463826186,2.7801310971571085,0.32709103081034985,-0.1930361462854971,1.409965539103894,0.13588174593938243,-0.2830431922681599,0.24265397388246301,1.483667990965456,0.13588174593938243,-0.4199698464474526,0.22140963170165096,0.15734698889488374,-0.6772732957307089,0.9930928138653216,1.9134596354218771,0.4314463011221435 | 3,039 |
oxidoreductase | 16 | 44 | 2.631127 | 0.00851 | P00403,O43169,Q15067,Q9Y6M9,Q8N0U8,O43678,O95831,O95168,Q86Y39,O15254,Q16134,O75306,P16435,O43676,O14949,Q8N4Q0 | Functions | Panther Protein class | panther_protein_class | 226,35,449,383,41,445,74,232,361,85,313,182,184,62,56,158 | 3030,915,56,85,35,839,2521,62,445,182,232,1166,74,505,226,2181,720,1987,184,2125,2074,1991,1893,2077,2892,2881,1356,932,1025,449,313,1501,2307,1613,936,361,41,158,2665,2668,2022,1577,466,383 | -3.4336046535863733,0.15734698889488374,2.843554170946297,2.472843405594802,3.3211717072673803,0.22140963170165096,-0.6535338132122217,2.7642080742589887,0.7169170935451981,1.6652764555563804,1.3542800263786563,0.005899515949245535,2.651981080000916,0.6160695351919047,1.3728811852532863,-0.46613729363893336,0.32709103081034985,-0.3740674450103724,1.629251338660244,-0.44302020696238215,-0.4199698464474526,-0.3740674450103724,-0.3284264225634382,-0.4199698464474526,-1.0922636419622016,-1.067229155753125,-0.08191648177571846,0.15734698889488374,0.09278259830834672,0.7169170935451981,1.0896107895774603,-0.14840553567250234,-0.5125735357359387,-0.1930361462854971,0.15734698889488374,0.9150913335574359,3.230580299955269,1.8256107323317246,-0.7489239882266361,-0.7489239882266361,-0.3740674450103724,-0.17069011224710406,0.69684344960622,0.875822884605927 | 3,039 |
Active transmembrane transporter activity | 26 | 71 | 2.626715 | 0.008621 | O96000,P13073,Q96QD8,Q9Y289,P20674,P53985,P03886,Q9H2J7,O75306,Q9UDW1,O43676,Q9H936,Q9HD20,O43678,P05023,Q9UBX3,Q96ES6,P51790,P00403,P51798,P16615,P08183,O95168,Q15388,Q7KZN9,Q9Y6M9 | Functions | GO Molecular function | msigdb_gomf | 505,386,270,540,32,412,38,442,182,54,62,456,66,445,334,77,346,219,226,101,233,107,232,114,371,383 | 3030,915,779,2521,62,445,1043,1044,182,1239,232,1166,782,2651,505,226,38,334,757,698,107,783,1243,740,759,721,386,233,2033,760,32,1246,1888,986,2378,2379,2632,2194,2654,2881,219,101,1356,723,412,2784,844,928,529,114,900,1501,2307,371,801,346,270,775,442,456,66,2989,2486,1520,77,54,1190,540,1342,3006,383 | -3.4336046535863733,0.15734698889488374,0.26384394974348613,-0.6535338132122217,2.7642080742589887,0.7169170935451981,0.07114797485870293,0.07114797485870293,1.6652764555563804,-0.037890347716938104,1.3542800263786563,0.005899515949245535,0.26384394974348613,-0.7489239882266361,0.6160695351919047,1.3728811852532863,3.275983050297943,1.0124830674261933,0.2849798960714869,0.34806687646145595,2.1719878809978588,0.26384394974348613,-0.037890347716938104,0.3060621463513644,0.2849798960714869,0.32709103081034985,0.856120860427004,1.3542800263786563,-0.39698574608401843,0.2849798960714869,3.4554772633739423,-0.037890347716938104,-0.3284264225634382,0.11436040160061789,-0.5592824068345678,-0.5592824068345678,-0.724967851906094,-0.46613729363893336,-0.7489239882266361,-1.067229155753125,1.409965539103894,2.273374172038848,-0.08191648177571846,0.32709103081034985,0.7768548054179463,-0.8942192990435678,0.22140963170165096,0.15734698889488374,0.5753910503793658,2.120868736002922,0.17875648445362774,-0.14840553567250234,-0.5125735357359387,0.895479624968376,0.26384394974348613,0.9736587559602312,1.2229517085712236,0.2849798960714869,0.7369433540186023,0.7169170935451981,2.748257927082434,-1.719172153536557,-0.606267828635831,-0.14840553567250234,2.603467193814167,2.890842077222198,0.005899515949245535,0.5753910503793658,-0.059873687391535715,-2.0820597615696625,0.875822884605927 | 3,039 |
Sphingolipid biosynthetic process | 9 | 15 | 2.624969 | 0.008666 | P27544,Q13510,Q16739,P04062,Q96G23,O95470,Q9P035,Q06136,O15269 | Processes and pathways | GO Biological process | msigdb_gobp | 161,6,265,171,44,140,443,349,347 | 347,595,140,171,2706,161,349,6,265,651,452,44,1377,443,1338 | 0.9541806525094901,0.47282605375654435,1.9134596354218771,1.7190419968762196,-0.7970566811673792,1.8079372376287888,0.9541806525094901,4.797294388390134,1.2418343865431385,0.4106794033765102,0.7169170935451981,3.154426526604387,-0.08191648177571846,0.7369433540186023,-0.059873687391535715 | 3,039 |
Juvenile onset | 8 | 40 | 2.62157 | 0.008753 | P51798,Q13510,O14773,P16278,P54802,Q14566,O15118,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 101,6,231,16,113,280,93,191 | 231,93,1043,1050,1979,1297,191,1594,1169,16,2188,1249,1932,1933,1739,2654,600,1018,2384,676,925,2689,101,113,1257,964,746,798,6,2138,280,319,2216,1505,2356,1952,2808,640,2547,737 | 1.3542800263786563,2.35701295367094,0.07114797485870293,0.07114797485870293,-0.3740674450103724,-0.059873687391535715,1.574937930723592,-0.1930361462854971,0.005899515949245535,3.9467246428005365,-0.46613729363893336,-0.037890347716938104,-0.35121448743560607,-0.35121448743560607,-0.2604471495603937,-0.7489239882266361,0.47282605375654435,0.09278259830834672,-0.5592824068345678,0.36899000714620145,0.15734698889488374,-0.7729534155941898,2.273374172038848,2.120868736002922,-0.037890347716938104,0.13588174593938243,0.3060621463513644,0.26384394974348613,4.797294388390134,-0.44302020696238215,1.2040279643762803,1.070393382836239,-0.46613729363893336,-0.14840553567250234,-0.5358936496388635,-0.35121448743560607,-0.9187001949064155,0.4314463011221435,-0.6535338132122217,0.32709103081034985 | 3,039 |
Elevated pulmonary artery pressure | 7 | 21 | 2.620936 | 0.008769 | P20674,P00403,P51798,P03886,O75844,P04062,Q14108 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,226,101,38,73,171,22 | 779,2859,73,505,226,1979,38,171,32,2878,1642,1387,2079,101,1356,22,799,339,2942,1666,1114 | 0.26384394974348613,-1.0174023844038849,2.668096362263561,0.6160695351919047,1.3728811852532863,-0.3740674450103724,3.275983050297943,1.7190419968762196,3.4554772633739423,-1.067229155753125,-0.21544405120141735,-0.10401912304964674,-0.4199698464474526,2.273374172038848,-0.08191648177571846,3.7041893683460807,0.26384394974348613,0.9930928138653216,-1.2955321839628167,-0.21544405120141735,0.04945616636338176 | 3,039 |
Oxidoreductase | 33 | 111 | 2.616635 | 0.00888 | Q14739,Q15800,P00374,Q9H7Z7,Q15392,P14406,Q14534,Q9H9P8,O15260,Q8N4Q0,P20674,Q6ZRP7,O43169,P03886,Q8N0U8,Q9BY49,Q14914,Q16850,Q9UDW1,O75306,Q16134,Q96CU9,O76062,Q15067,O95831,Q7LG56,O15254,P00403,P49748,Q9Y6M9,Q13423,O95168,P05091 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 260,264,393,271,281,146,148,156,27,158,32,416,35,38,41,431,177,52,54,182,313,61,324,449,74,212,85,226,228,383,102,232,117 | 3030,2625,915,85,27,35,527,2237,2521,445,1587,1044,182,474,2891,324,232,74,888,1050,920,393,1534,226,38,2181,2068,117,2525,1595,720,740,3024,1014,2630,1987,1782,146,1836,2631,1538,841,32,789,2593,2879,2467,2378,2427,2560,1929,1484,1128,2340,791,2840,1992,520,2077,1894,2707,793,2655,3014,228,2384,1449,2689,1356,1312,926,1788,2951,796,2255,2347,102,148,260,177,449,281,264,313,1501,2307,52,2397,1613,416,1222,212,41,158,904,2773,731,61,2665,2668,535,431,271,1625,156,578,1520,1626,1233,54,383 | -3.4336046535863733,-0.724967851906094,0.15734698889488374,2.472843405594802,3.6025482837872342,3.3211717072673803,0.5753910503793658,-0.48932157771479984,-0.6535338132122217,0.7169170935451981,-0.1930361462854971,0.07114797485870293,1.6652764555563804,0.6565529155942527,-1.0922636419622016,1.0511331158891664,1.3542800263786563,2.651981080000916,0.17875648445362774,0.07114797485870293,0.15734698889488374,0.8363732981403815,-0.17069011224710406,1.3728811852532863,3.275983050297943,-0.46613729363893336,-0.4199698464474526,2.1037649504595,-0.6535338132122217,-0.1930361462854971,0.32709103081034985,0.3060621463513644,-2.803971123021496,0.09278259830834672,-0.724967851906094,-0.3740674450103724,-0.2830431922681599,1.895958450657215,-0.3057028045175211,-0.724967851906094,-0.17069011224710406,0.22140963170165096,3.4554772633739423,0.26384394974348613,-0.7010844658862807,-1.067229155753125,-0.606267828635831,-0.5592824068345678,-0.5827403002940941,-0.6772732957307089,-0.35121448743560607,-0.14840553567250234,0.027706804197958748,-0.5358936496388635,0.26384394974348613,-0.9678943672344994,-0.3740674450103724,0.5957548236023519,-0.4199698464474526,-0.3284264225634382,-0.7970566811673792,0.26384394974348613,-0.7489239882266361,-2.255823209902375,1.3728811852532863,-0.5592824068345678,-0.12618200751855965,-0.7729534155941898,-0.08191648177571846,-0.059873687391535715,0.15734698889488374,-0.2830431922681599,-1.3472055809727788,0.26384394974348613,-0.48932157771479984,-0.5358936496388635,2.273374172038848,1.895958450657215,1.2606762141367405,1.6832344093740115,0.7169170935451981,1.2040279643762803,1.2418343865431385,1.0896107895774603,-0.14840553567250234,-0.5125735357359387,2.9847119746833544,-0.5592824068345678,-0.1930361462854971,0.7768548054179463,-0.01596607463826186,1.4653001660607239,3.230580299955269,1.8256107323317246,0.17875648445362774,-0.8698150771053541,0.32709103081034985,2.7801310971571085,-0.7489239882266361,-0.7489239882266361,0.5753910503793658,0.7569225018513692,1.2229517085712236,-0.1930361462854971,1.843249435681901,0.5140024586389151,-0.14840553567250234,-0.1930361462854971,-0.01596607463826186,2.890842077222198,0.875822884605927 | 3,039 |
Morphological abnormality of the pyramidal tract | 7 | 21 | 2.614445 | 0.008937 | Q9Y4P3,O95831,O75298,P35637,Q9H9P8,P11166,P00846 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 261,74,151,244,156,310,63 | 151,1122,1590,74,63,310,786,1737,244,2085,2205,704,650,1793,1411,1322,156,716,2699,261,382 | 1.8608535136088946,0.027706804197958748,-0.1930361462854971,2.651981080000916,2.7642080742589887,1.0896107895774603,0.26384394974348613,-0.2604471495603937,1.3169587262701798,-0.4199698464474526,-0.46613729363893336,0.34806687646145595,0.4106794033765102,-0.2830431922681599,-0.10401912304964674,-0.059873687391535715,1.843249435681901,0.34806687646145595,-0.7729534155941898,1.2606762141367405,0.875822884605927 | 3,039 |
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