term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Dectin 1 mediated noncanonical nf kb signaling
10
43
3.015074
0.002569
P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,50,518,621,449,123,62
589,2839,2113,590,1188,1709,1712,449,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,2470,1011,1640,1733,1890,1810,1139,2803,2399,3384,1654,1975,1824,621,1165,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.0032099369180387514,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444...
3,642
Auf1 hnrnp d0 binds and destabilizes mrna
10
42
3.008975
0.002621
P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,1446,785,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,1565,1139,2803,1572,3384,1654,1824,621,1165,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,0.10549180847782079,0.4676910964650831,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2...
3,642
Cdt1 association with the cdc6 orc origin complex
11
42
3.004435
0.002661
P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070,Q9Y619
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,50,518,621,449,123,62,299
589,2839,2113,590,1188,1712,2912,449,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,1139,2803,1307,3384,1654,1824,621,1165,2514,518,1523,299
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.5833007240749342,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3....
3,642
Metabolism of polyamines
10
40
2.967461
0.003003
P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,824,2296,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2747,2307,568,1011,1640,1733,1890,1139,2803,3384,1654,1824,621,1165,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,0.4314806144175144,-0.2569259022510854,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3....
3,642
Organelle inner membrane
78
286
2.965293
0.003024
P49748,P52815,Q99720,Q70HW3,Q99595,Q9Y6N5,Q14739,O60830,Q9BYD2,P03886,Q9Y5J6,Q13185,Q15070,O43772,O95831,Q03252,Q9H4I9,P00403,Q6DKK2,P23786,P62995,P82932,O75380,Q69YU5,Q8N442,Q9BQT8,O60313,Q9HD33,O95167,O75964,Q9NQ50,Q9Y2R0,Q9Y5J9,Q8N983,Q9BTV4,Q9H3K2,O43676,P20674,Q567V2,Q13405,O95139,P21912,Q9BYD3,P00846,P56556,Q6UX0...
Localization
GO Cellular component
msigdb_gocc
494,495,9,17,22,557,31,33,582,49,588,573,574,59,64,571,66,560,69,74,569,570,79,82,619,624,90,627,595,108,115,121,122,663,667,670,136,139,140,654,634,638,152,162,645,704,178,714,176,681,184,208,203,205,221,212,229,234,268,264,275,299,295,292,287,340,337,344,343,374,377,365,388,390,391,394,469,521
1186,2280,343,1859,344,1048,2010,136,2011,59,1372,90,33,3572,1375,993,79,3172,234,1713,1281,2448,2364,3133,1865,871,388,108,2368,3428,2725,634,595,2450,184,1441,2120,3289,1791,64,681,1793,3400,560,162,49,2729,2371,3089,390,3249,2213,2918,2453,936,1795,1445,2217,3363,3475,3015,1379,727,3136,391,683,937,2127,365,1288,139...
0.21417390765469435,-0.2569259022510854,0.9020601005809601,-0.07568886835881676,0.9020601005809601,0.28661790671407417,-0.14817681559539894,1.5892531387800641,-0.14817681559539894,2.4202850586689473,0.14172133947363577,1.986811502084436,3.286571983805788,-1.8545831244298248,0.14172133947363577,0.3228367256941829,2.1313...
3,642
EF-Hand 1, calcium-binding site [IPR018247]
10
41
2.95618
0.003115
Q9Y680,Q9NWM8,Q9NZM3,P80303,O43852,Q02818,Q14257,Q96AY3,P0DP25,Q8NI22
Sequence
InterPro Binding site
interpro_binding_site
101,71,106,11,78,15,80,54,85,61
445,78,2207,3133,1441,2653,1718,85,488,2658,417,1625,2735,1383,1056,566,686,1800,11,15,3294,370,80,2756,1020,1661,2409,2252,61,54,3494,3578,132,716,1767,71,106,813,3635,1933,101
0.7573020385339275,2.1313283265493896,-0.2206738976316064,-0.7647060824085025,0.10549180847782079,-0.43822119087257283,-0.0032099369180387514,2.059073169203502,0.7211076503875371,-0.43822119087257283,0.7934944666326158,0.03302618423136544,-0.4744874152715812,0.14172133947363577,0.28661790671407417,0.6487129491004436,0....
3,642
Recruitment of mitotic centrosome proteins and complexes
18
39
2.949933
0.003178
O15078,O75935,P61163,P62258,Q9UPN4,Q96CW5,Q9NXR1,P41208,Q9BSJ2,P30153,O94927,O43805,Q15691,Q14203,Q9H6D7,O95684,Q96CS2,Q13561
Processes and pathways
Reactome Pathways
msigdb_reactome
345,102,498,499,442,291,181,566,407,419,322,200,371,329,88,58,92,190
345,200,102,322,58,1716,872,1870,1051,3175,1452,789,419,566,2744,3292,498,1212,499,3255,1892,796,190,2400,329,3295,611,371,2404,1582,2873,92,291,1682,407,1261,88,181,442
0.9020601005809601,1.299988629982995,1.8784066596115039,0.9382447978183553,2.4563975818909127,-0.0032099369180387514,0.39526806690703153,-0.07568886835881676,0.28661790671407417,-0.8009947951684113,0.10549180847782079,0.4676910964650831,0.7934944666326158,0.6487129491004436,-0.4744874152715812,-0.9098765594461098,0.721...
3,642
Hedgehog on state
11
44
2.948746
0.003191
P28072,P49721,O00231,O00487,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,590,568,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,824,50,1199,828,1628,1722,1126,62,34,1200,2532,2224,1727,1007,1061,123,5,1207,2307,568,1011,1640,1733,1890,1139,2803,1961,3384,1654,1662,1824,2418,621,1165,518,1523,677
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3.0700792274589883,0.2...
3,642
Signaling by notch4
10
45
2.94491
0.00323
P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,824,50,1199,828,1628,1722,1126,62,34,1200,1001,2224,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,1471,1810,1013,1139,2803,797,2399,1654,1824,3067,621,1165,518,1523,2003
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3.0700792274589883,0.2...
3,642
Endopeptidase complex
17
53
2.915213
0.003554
P28072,P49721,Q96S52,O75832,O00231,O00487,P60900,O43396,Q92643,Q9UMX0,P20618,P17980,Q9UL46,Q99436,P28070,P49720,P54727
Localization
GO Cellular component
msigdb_gocc
34,5,807,449,589,590,568,722,248,519,50,824,518,621,62,123,688
589,2839,2113,590,1188,1712,2358,722,449,2653,1625,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,1806,688,2307,1466,568,1011,1640,1733,1890,1139,2803,3384,1654,1656,2317,2482,1824,248,1980,807,621,1165,518,519,1523,2716
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.293180236639351,0.50389952531643,0.7573020385339275,-0.43822119087257283,0.03302618423136544,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.00...
3,642
Foot dorsiflexor weakness
14
33
2.912928
0.003581
Q9Y281,P06753,Q9NR77,P39210,Q99720,P07196,Q7LG56,O14908,Q15046,P02545,Q9BQT8,P38935,Q96BR5,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,682,267,212,9,73,429,482,696,726,624,454,540,31
2719,482,3170,2964,1372,1788,726,2372,682,73,454,212,1549,1802,2032,833,1553,1466,2538,1651,1573,31,696,743,2161,3063,1492,429,540,9,624,267,297
-0.4744874152715812,0.7211076503875371,-0.8009947951684113,-0.6195767634991557,0.14172133947363577,-0.039448282981301534,0.50389952531643,-0.293180236639351,0.5401059130940894,2.2035770349778274,0.7573020385339275,1.2638225352277326,0.06926009468413799,-0.039448282981301534,-0.14817681559539894,0.4314806144175144,0.069...
3,642
Programmed cell death
31
106
2.900248
0.003729
Q16625,P49721,P41440,Q9H444,P62258,P08670,P31946,P42771,Q9NR28,P28072,Q13177,Q04917,P20618,P28070,Q07021,P31751,P60900,Q07157,P26583,Q99436,O75832,O60313,Q9P289,O00231,O00487,P49354,Q9Y3E7,Q13813,P35611,Q9UL46,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
659,5,6,671,499,148,639,642,157,34,652,532,50,62,186,564,568,690,324,621,449,90,766,589,590,237,383,370,605,518,123
2838,589,2839,2113,1706,1110,590,3448,1188,2521,1712,1371,90,449,2119,726,1717,3250,1051,148,2214,2734,3596,2025,2921,824,50,788,1199,828,1628,1722,324,1382,2379,1126,62,34,1200,2740,3048,1001,564,639,1876,605,2224,3178,6,642,1727,1007,2930,237,123,5,1465,1207,1805,2307,568,1011,1212,1640,1733,499,1890,1471,3255,532,33...
-0.5470271646093248,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,-0.0032099369180387514,0.2503969717100796,0.6125126132127564,-1.2003461062830174,0.21417390765469435,-0.36569595808664096,-0.0032099369180387514,0.14172133947363577,1.986811502084436,0.7573020385339275,-0.18442420720352415,0.50389952531643,...
3,642
Orc1 removal from chromatin
13
52
2.897295
0.003764
P28072,P49721,O00231,O00487,P60900,P33993,P20618,Q9UL46,Q99436,O75832,P49720,P28070,Q9Y619
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,590,568,565,50,518,621,449,123,62,299
589,2839,2113,590,1188,1712,2912,449,824,50,1627,882,1199,828,1628,1722,1126,62,34,1200,1002,2607,565,2224,1727,1007,123,5,644,1207,2307,568,1011,1640,1733,1890,1810,1139,2803,1570,1307,2399,1653,3384,1654,1824,621,1165,2514,518,1523,299
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.5833007240749342,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.03302618423136544,0.39526806690703153,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514...
3,642
Synthesis of dna
23
88
2.896207
0.003777
Q9NRF9,P49721,P41440,Q9UJX4,P40937,P49736,Q9Y619,P28072,P20618,P28070,P33993,P60900,Q9BRT9,Q99436,Q9NR33,O75832,Q16763,O00231,Q9UJX3,O00487,Q9Y248,Q9UL46,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
269,5,6,412,641,644,299,34,50,62,565,568,207,621,220,449,98,589,770,590,772,518,123
589,2839,2113,590,1188,1712,2912,3472,449,2845,2021,875,824,729,50,1627,882,1199,828,1628,1722,2925,1126,62,34,1200,1629,2381,1002,2607,565,3177,1947,1799,2223,2224,1059,641,1547,6,1727,1007,1062,2031,1131,123,5,644,1207,2307,892,568,1011,1640,1733,1890,1810,1139,2677,2803,1570,1307,2399,3491,1653,3384,1654,98,1824,207...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.5833007240749342,-1.2729912830023138,0.7573020385339275,-0.5470271646093248,-0.14817681559539894,0.39526806690703153,0.4314806144175144,0.50389952531643,2.7091423080596084,0.03302618423136544,0.3...
3,642
Peptidase complex
20
63
2.894016
0.003803
P49721,Q96S52,Q9NPA8,Q9UPT9,P67812,P28072,P20618,P28070,P54727,P60900,P17980,Q99436,O75832,O00231,O00487,O43396,Q92643,Q9UMX0,Q9UL46,P49720
Localization
GO Cellular component
msigdb_gocc
5,807,549,144,648,34,50,62,688,568,824,621,449,589,590,722,248,519,518,123
589,2839,2113,590,1188,1712,2358,722,2447,449,2653,1625,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,1806,688,2307,1466,568,1134,1011,1640,1733,1890,648,1139,2860,2803,3384,2050,1654,1656,2317,2482,1824,248,1980,3197,807,621,1165,549,518,519,1523,144,2835,1428,2716
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.293180236639351,0.50389952531643,-0.32943691658390756,0.7573020385339275,-0.43822119087257283,0.03302618423136544,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03...
3,642
The role of gtse1 in g2 m progression after g2 checkpoint
11
49
2.892917
0.003817
P28072,P49721,O00231,P60900,Q15691,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,371,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,1716,1717,872,1051,1376,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,3292,2307,568,1011,1640,1733,1890,1892,1139,2803,1652,3384,1654,371,1824,621,1165,2089,973,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,-0.0032099369180387514,-0.0032099369180387514,0.39526806690703153,0.28661790671407417,0.14172133947363577,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175...
3,642
Distal muscle weakness
18
70
2.885739
0.003905
P18887,O95831,Q71SY5,Q9NR77,P00846,P41440,Q99720,P35637,Q7LG56,P07196,Q96T60,Q8TD16,Q00796,Q14203,P38935,O14908,Q7Z406,P39210
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
489,64,164,267,162,6,9,286,429,73,544,113,326,329,454,482,317,212
482,3170,2964,2207,1282,1788,2594,64,162,726,682,73,996,1871,2601,489,2846,1873,1380,2223,286,1203,454,212,2928,1948,6,1726,1549,1802,1636,2032,2976,833,1730,1466,1952,3221,326,1566,1738,329,3295,1573,1483,2161,3483,2481,3228,3063,2063,1492,164,429,317,1973,3195,113,540,3623,1831,544,9,624,267,2348,2579,1428,3042,817
0.7211076503875371,-0.8009947951684113,-0.6195767634991557,-0.2206738976316064,0.17794870135979338,-0.039448282981301534,-0.40195737736821424,2.348055342926024,1.44463503950887,0.50389952531643,0.5401059130940894,2.2035770349778274,0.3228367256941829,-0.07568886835881676,-0.40195737736821424,0.7211076503875371,-0.54702...
3,642
Mitotic prometaphase
28
108
2.870872
0.004093
P55735,P61163,Q9BSJ2,P67870,Q9BS16,Q9UPN4,Q96CW5,Q9NXR1,P30153,O60566,P36873,Q96IY1,O95684,Q13561,Q8NBT2,Q9Y6D9,O94927,O43805,Q9H3R5,Q14203,Q9H6D7,Q96CS2,O15078,Q96EA4,Q6P1K2,O75935,Q15691,Q12834
Processes and pathways
Reactome Pathways
msigdb_reactome
497,498,407,393,156,442,291,181,419,301,420,319,58,190,468,65,322,200,86,329,88,92,345,100,507,102,371,119
1046,2786,345,868,1861,2284,200,2359,301,3044,102,322,1621,58,1716,872,1870,1051,3175,1719,789,419,884,420,566,2744,2225,2974,2466,2853,3292,497,1639,498,1212,499,3255,393,1892,1137,1069,3404,119,1221,1018,796,190,1652,2400,329,3295,1741,2049,2546,1899,2050,2157,611,371,1079,1486,1150,802,2404,3492,507,958,1582,2873,28...
0.28661790671407417,-0.5107560674697893,0.9020601005809601,0.39526806690703153,-0.07568886835881676,-0.2569259022510854,1.299988629982995,-0.293180236639351,1.0106084847967511,-0.6921363540246968,1.8784066596115039,0.9382447978183553,0.03302618423136544,2.4563975818909127,-0.0032099369180387514,0.39526806690703153,-0.0...
3,642
Centrosome
51
191
2.86873
0.004121
Q9Y496,Q13432,P41440,P53990,P61163,Q9BSJ2,P16219,Q9UJC3,Q9Y366,Q9H981,Q9UPN4,Q96CW5,Q9NXR1,Q5SW79,O95684,Q86UY6,Q13561,Q9Y6D9,Q9UIJ7,Q6DKK2,P41208,A0AVF1,Q96RK4,O94927,Q14498,O43805,O14974,P0DP25,Q9UPT5,Q9H6D7,Q14203,Q9Y5Y2,Q96CS2,Q9Y5K6,O15078,Q15154,O75935,P16104,Q9H814,O43809,Q9NZM3,Q9Y448,Q9Y5K8,Q15650,Q8TD16,Q1569...
Localization
GO Cellular component
msigdb_gocc
677,129,6,496,498,407,637,294,443,40,442,291,181,304,58,191,190,65,339,69,566,558,206,322,463,200,321,85,629,88,329,252,92,630,345,611,102,600,378,592,106,244,522,238,113,371,233,119,606,363,487
558,1046,2281,1782,3551,321,345,868,2358,200,592,776,233,1374,1280,1863,3472,3012,680,102,2119,322,58,363,1717,2915,872,1196,2020,997,85,487,1942,2021,998,600,637,3175,1943,789,1627,882,1199,2795,1200,829,2381,732,1876,1129,1724,2136,606,2304,566,6,2744,643,2227,1061,1462,891,1636,1804,1464,2034,1729,3292,3585,1209,496...
0.6487129491004436,0.28661790671407417,-0.2569259022510854,-0.039448282981301534,-1.6727503201710714,0.9382447978183553,0.9020601005809601,0.39526806690703153,-0.293180236639351,1.299988629982995,0.6125126132127564,0.4676910964650831,1.1914848887169478,0.14172133947363577,0.17794870135979338,-0.07568886835881676,-1.272...
3,642
Hedgehog off state
13
54
2.865052
0.004169
P28072,Q9Y366,P49721,O00231,O00487,P10644,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,443,5,589,590,487,568,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,1716,487,998,3175,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,1061,123,5,1462,1207,2307,568,1011,1640,1733,1890,1810,1892,1139,2803,2399,1652,3384,1654,3030,1824,2418,621,1165,2089,973,518,1523,443,677
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,-0.0032099369180387514,0.7211076503875371,0.3228367256941829,-0.8009947951684113,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-...
3,642
Degradation of gli1 by the proteasome
10
42
2.855524
0.004297
P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,3175,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,1810,1139,2803,2399,3384,1654,1824,2418,621,1165,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,-0.8009947951684113,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3....
3,642
Proteasome complex
11
47
2.852002
0.004344
P28072,P49721,O00231,P60900,Q9UMX0,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Localization
GO Cellular component
msigdb_gocc
34,5,589,568,519,50,518,621,449,123,62
589,2839,2113,590,1188,1712,722,449,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,1806,688,2307,1466,568,1011,1640,1733,1890,1139,2803,3384,1654,1656,2317,2482,1824,621,1165,518,519,1523,2716
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.50389952531643,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3.070...
3,642
Recruitment of numa to mitotic centrosomes
18
42
2.843517
0.004462
O15078,O75935,P61163,P62258,Q9UPN4,Q96CW5,Q9NXR1,P41208,Q9BSJ2,P30153,O94927,O43805,Q15691,Q14203,Q9H6D7,O95684,Q96CS2,Q13561
Processes and pathways
Reactome Pathways
msigdb_reactome
345,102,498,499,442,291,181,566,407,419,322,200,371,329,88,58,92,190
345,200,102,322,58,1716,872,1870,1051,3175,789,419,566,2744,3292,498,1212,499,3255,1892,796,190,1652,2400,329,3295,2546,611,371,2404,1582,2873,92,291,1682,407,2089,1261,973,88,181,442
0.9020601005809601,1.299988629982995,1.8784066596115039,0.9382447978183553,2.4563975818909127,-0.0032099369180387514,0.39526806690703153,-0.07568886835881676,0.28661790671407417,-0.8009947951684113,0.4676910964650831,0.7934944666326158,0.6487129491004436,-0.4744874152715812,-0.9098765594461098,0.7211076503875371,0.2141...
3,642
Fceri mediated nf kb activation
10
46
2.832345
0.004621
P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,50,518,621,449,123,62
589,2839,2113,590,1188,2963,1709,1712,2587,449,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,894,1011,1640,1733,1890,1810,1139,2803,1649,2399,3384,1654,2054,1824,621,1165,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.6195767634991557,-0.0032099369180387514,-0.0032099369180387514,-0.40195737736821424,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.003209936918038...
3,642
Inner mitochondrial membrane protein complex
21
89
2.830054
0.004654
O43676,P20674,O75947,Q99595,P06576,P22695,O60830,P00846,P03886,Q9H4I9,O95182,Q9NWR8,Q9NX63,Q13505,O75380,O14949,O14548,Q96CU9,O75964,O75438,P18859
Localization
GO Cellular component
msigdb_gocc
136,139,388,22,390,275,33,162,49,66,184,337,208,203,79,344,343,374,108,234,365
1186,2280,343,1859,344,2010,136,2011,33,1375,993,79,3172,234,1281,388,108,634,595,2450,184,2120,681,3400,560,162,49,2729,390,2213,936,1445,3015,727,3136,391,683,365,1288,139,638,275,730,2458,1201,1632,790,1128,791,2385,1299,2611,3179,1953,1886,2038,645,203,1021,2402,1315,1902,3296,844,3111,1906,3517,1974,374,3235,22,11...
0.21417390765469435,-0.2569259022510854,0.9020601005809601,-0.07568886835881676,0.9020601005809601,-0.14817681559539894,1.5892531387800641,-0.14817681559539894,3.286571983805788,0.14172133947363577,0.3228367256941829,2.1313283265493896,-0.8009947951684113,1.1914848887169478,0.17794870135979338,0.8296849457389607,1.8061...
3,642
Oxidative phosphorylation
29
69
2.800008
0.00511
Q9H3K2,O43676,P20674,O95139,O75947,P06576,P14927,P22695,Q9UJZ1,P00846,O75323,P56556,P31930,P03886,Q9BSK2,O96000,P00403,O95182,P15954,O75380,O14949,O14548,O95167,O75964,P13073,O75438,P24539,P27144,P18859
Processes and pathways
GO Biological process
msigdb_gobp
670,136,139,634,388,390,391,275,295,162,165,645,790,49,714,681,560,184,683,79,344,343,595,108,727,234,730,731,365
1186,2280,343,344,2010,136,2011,1375,993,165,79,234,1281,388,108,634,595,2450,184,2120,681,3400,560,162,49,2729,872,390,2213,2215,1445,727,3136,391,683,365,1288,139,275,730,2458,731,1201,2133,1632,790,1545,791,1298,1299,2611,3179,1466,1953,2038,645,1021,2402,3451,1320,1336,2956,3443,2420,714,670,1043,295,2519
0.21417390765469435,-0.2569259022510854,0.9020601005809601,0.9020601005809601,-0.14817681559539894,1.5892531387800641,-0.14817681559539894,0.14172133947363577,0.3228367256941829,1.4084761139436706,2.1313283265493896,1.1914848887169478,0.17794870135979338,0.8296849457389607,1.8061284441617231,0.5763102717789569,0.612512...
3,642
Muscle cell differentiation
15
73
2.790561
0.005262
Q9Y281,Q96PU8,Q9H7B4,Q96EB6,P41440,Q53EL6,Q13049,Q14012,Q7Z4V5,O43707,P09493,Q9NYL9,P19022,P10644,P12814
Processes and pathways
GO Biological process
msigdb_gobp
297,435,4,292,6,226,43,397,145,445,174,116,312,487,488
445,776,1784,1785,1374,931,1865,2119,1714,726,2124,2844,872,174,487,3606,1942,488,1448,1625,312,2026,1543,1292,883,1127,1001,2532,2461,1876,1057,6,2743,1008,944,2034,1555,1472,3018,2149,3257,2238,3223,691,43,3144,397,1573,1077,1483,1901,2246,1080,226,1972,145,3148,2077,292,1030,435,1504,3624,1684,547,2185,1767,4,116,16...
0.7573020385339275,0.4676910964650831,-0.039448282981301534,-0.039448282981301534,0.14172133947363577,0.3590534415201943,-0.07568886835881676,-0.18442420720352415,-0.0032099369180387514,0.50389952531643,-0.18442420720352415,-0.5470271646093248,0.39526806690703153,1.3723154099889678,0.7211076503875371,-2.400586343744602...
3,642
Cellular modified amino acid metabolic process
7
57
2.786047
0.005336
P00374,Q8NCC3,Q9UHG3,P41440,O60725,P23786,P48507
Processes and pathways
GO Biological process
msigdb_gobp
0,2,37,6,137,74,177
2784,1858,300,2523,723,137,933,1117,0,1283,2019,2124,2371,3606,1942,2218,2293,1379,874,684,3251,2131,74,1946,2848,2380,2382,2301,1545,6,1635,177,1460,3565,3432,3625,2391,3436,1477,2394,2979,2548,1491,2693,1086,2,3567,2956,2994,1342,2826,229,1035,438,37,2108,2715
-0.5107560674697893,-0.07568886835881676,1.0106084847967511,-0.36569595808664096,0.50389952531643,1.5892531387800641,0.3590534415201943,0.2503969717100796,9.69022063780281,0.17794870135979338,-0.14817681559539894,-0.18442420720352415,-0.293180236639351,-2.4005863437446022,-0.11193170763769089,-0.2206738976316064,-0.256...
3,642
Mitochondria
68
462
2.778484
0.005461
P00374,Q5JPH6,Q9BYN8,Q9BXK5,Q70HW3,Q7Z4V5,Q16740,Q9NQH7,Q9H3H1,Q99595,O75947,P06576,P22695,Q96H78,Q96A26,Q9NR28,Q9HCL2,P13674,P82912,O60830,O75323,Q96EB6,Q13084,Q8WVI0,Q96HJ9,Q86VD7,Q9P0J1,Q9GZY8,P30837,Q96AY3,Q9NS69,O43772,P28070,O95831,Q9H4I9,Q07820,Q07021,O95182,Q9Y5L4,Q6DKK2,O00165,Q9UIJ7,P23786,Q9NX63,Q9NWR8,Q1350...
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
0,401,264,142,17,145,279,20,282,22,388,390,275,27,155,157,30,274,394,33,165,292,287,42,306,178,47,51,53,54,55,59,62,64,66,187,186,184,340,69,72,339,74,208,337,203,205,333,331,82,327,90,228,251,229,344,343,374,108,243,110,241,375,115,118,234,121,365
72,1186,2198,2355,2280,343,2005,2116,1859,344,2520,3332,2647,2358,1048,2010,59,1372,1437,90,2721,1191,447,33,3572,3086,993,165,3335,2650,3172,234,1713,1281,2843,2448,2364,2209,2012,388,108,2368,1714,3245,634,1788,2450,184,1441,2120,64,1793,0,3400,2124,2597,1717,3089,3462,390,2212,2733,2213,1794,2215,936,1795,2657,1445,...
2.2035770349778274,0.21417390765469435,-0.2206738976316064,-0.293180236639351,-0.2569259022510854,0.9020601005809601,-0.14817681559539894,-0.18442420720352415,-0.07568886835881676,0.9020601005809601,-0.36569595808664096,-0.9824776229443855,-0.43822119087257283,-0.293180236639351,0.28661790671407417,-0.14817681559539894...
3,642
Transcriptional regulation by runx1
15
72
2.776853
0.005489
P28072,P49721,O00231,O75832,O00487,Q12824,P60900,P20618,Q9UL46,Q99436,P16104,P28070,P67870,P49720,Q9HCL2
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,449,590,534,568,50,518,621,600,62,393,123,30
589,2839,2113,590,1187,1188,2117,1712,449,2526,600,937,824,1719,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,2798,1207,2307,568,1011,3103,1640,1733,1890,2148,393,1137,2149,2043,3019,1139,690,534,2803,3144,3384,1654,2051,659,2619,2624,2256,1824,1979,1826,1090,1257,2418,2767,621,1165,854,2769,2181,1990,2340...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,0.21417390765469435,-0.18442420720352415,-0.0032099369180387514,0.7573020385339275,-0.36569595808664096,0.6125126132127564,0.3590534415201943,0.4314806144175144,-0.0032099369180387514,2.7091423080596084,0.2141739076546943...
3,642
Signaling by the b cell receptor bcr
12
48
2.776712
0.005491
P28072,P49721,O00231,P60900,P49720,P20618,Q9UL46,Q99436,P62993,O75832,P62942,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,123,50,518,621,278,449,60,62
589,2839,2113,590,1188,2963,1709,1712,2587,821,449,3576,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,60,278,1810,1139,2238,2803,2399,3384,1654,1824,621,1165,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.6195767634991557,-0.0032099369180387514,-0.0032099369180387514,-0.40195737736821424,0.4314806144175144,0.7573020385339275,-1.8909594859139407,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144...
3,642
Oxidative phosphorylation
28
68
2.770019
0.005605
O43676,P20674,O95139,O75947,P06576,P21912,P14927,P36543,P22695,P00846,P56556,P31930,P03886,O96000,P00403,O95182,P15954,O75380,O14949,O14548,Q9Y5K8,O95167,O75964,P21281,P13073,O75438,P24539,P18859
Processes and pathways
KEGG Pathways
msigdb_kegg
136,139,634,388,390,638,391,276,275,162,645,790,49,681,560,184,683,79,344,343,522,595,108,601,727,234,730,365
1186,2280,343,344,2010,136,2011,1375,993,79,234,1281,388,108,634,595,2450,184,2120,681,3400,560,162,49,2729,390,2213,936,1445,727,3136,391,683,365,1288,139,601,2792,638,275,730,2458,1201,1632,790,791,276,2384,1299,2611,3179,1953,2038,645,1211,3024,3267,1021,2402,1320,1906,1089,2705,1043,2106,1275,522,2519
0.21417390765469435,-0.2569259022510854,0.9020601005809601,0.9020601005809601,-0.14817681559539894,1.5892531387800641,-0.14817681559539894,0.14172133947363577,0.3228367256941829,2.1313283265493896,1.1914848887169478,0.17794870135979338,0.8296849457389607,1.8061284441617231,0.5763102717789569,0.6125126132127564,-0.32943...
3,642
Degradation of beta catenin by the destruction complex
11
52
2.766008
0.005675
P28072,P49721,O00231,P60900,P30153,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,419,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,824,50,1199,828,1628,1722,1126,62,34,1200,419,884,1876,2224,1727,1007,1061,123,5,1462,1207,2307,1808,568,1011,1640,1733,1890,1810,1138,1139,2803,1018,950,3144,2399,2049,3384,1654,1079,1824,621,1165,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3.0700792274589883,0.2...
3,642
Signaling by notch
13
65
2.761344
0.005756
P28072,P49721,O00231,O00487,P60900,Q9BZK7,P20618,Q9UL46,Q99436,O75832,P78536,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,590,568,548,50,518,621,449,351,123,62
589,2839,2113,590,1188,1712,449,1717,823,600,1448,824,50,1199,828,1628,1722,1126,62,34,1200,1001,2532,2224,1949,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,2148,1471,1810,1472,351,2149,1013,1138,1139,2803,3144,797,2399,1654,2682,2053,1824,3067,2496,2418,621,1165,548,2829,2340,1359,518,1523,2003
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,-0.0032099369180387514,0.4314806144175144,0.6125126132127564,0.10549180847782079,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-...
3,642
Apoptosis
32
92
2.750631
0.005948
Q16625,P49721,P62258,P08670,P31946,P42771,Q9NR28,P28072,Q13177,P20700,Q04917,P20618,P28070,Q07021,P31751,P60900,Q07157,P26583,P17980,Q99436,P25787,O75832,O60313,Q9P289,O00231,O00487,P02545,P49354,Q13813,P35611,Q9UL46,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
659,5,499,148,639,642,157,34,652,788,532,50,62,186,564,568,690,324,824,621,828,449,90,766,589,590,726,237,370,605,518,123
2838,589,2839,2113,1706,1110,590,1188,1712,90,449,726,1717,3250,148,2214,2734,3596,2025,2921,824,50,788,1199,828,1628,1722,324,1382,2379,1126,62,34,1200,2740,3048,1001,564,639,1876,605,2224,3178,642,1727,1007,2930,237,123,5,1465,1207,1805,2307,568,1011,1212,1640,1733,499,1890,1471,3255,532,3383,1139,186,690,652,2803,83...
-0.5470271646093248,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,-0.0032099369180387514,0.2503969717100796,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,1.986811502084436,0.7573020385339275,0.50389952531643,-0.0032099369180387514,-0.8735800140144077,1.516947591835183,-0.2206738976316064,-...
3,642
Transcriptional regulation by runx2
11
52
2.745715
0.006038
P28072,P31751,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,564,5,589,568,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,872,784,937,824,50,1199,828,1628,1722,2379,1126,62,34,1200,2740,1001,564,2224,1949,1727,1007,123,5,1462,1207,2307,568,1011,1640,1733,1890,1810,1139,2803,1570,2399,3384,1654,1824,1164,621,1165,518,2271,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,0.39526806690703153,0.4676910964650831,0.3590534415201943,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,-...
3,642
Cellular response to hypoxia
10
43
2.732968
0.006277
P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,568,50,518,621,449,123,62
589,2839,2113,590,1188,1712,449,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,1139,2803,1650,3384,1654,3266,3346,1824,621,1165,2101,518,1523,1612
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3.0700792274589883,0.2...
3,642
Diseases of signal transduction by growth factor receptors and second messengers
40
153
2.721542
0.006498
P49721,Q92734,Q9BZK7,P13984,P62993,P31946,P30086,O95429,P28072,Q01082,Q96PU8,P84095,P30153,P20618,P11274,P36873,O95684,O43252,P62942,P28070,Q13438,P06753,P67936,Q9NRY5,P31751,P60900,Q9UBW7,Q13555,Q99436,Q14203,P26038,P78536,O75832,O00231,O00487,P02545,Q9UL46,P33176,P49720,P10644
Processes and pathways
Reactome Pathways
msigdb_reactome
5,262,548,636,278,639,26,161,34,650,435,168,419,50,175,420,58,57,60,62,189,682,185,70,564,568,479,694,621,329,451,351,449,589,590,726,518,732,123,487
2279,589,2839,2113,1047,590,1188,1709,1431,1433,1712,57,990,449,1282,1194,3288,161,58,726,1196,682,1051,487,175,1053,636,824,825,2735,1796,877,50,2664,1199,828,1628,1722,451,1946,2379,1126,62,34,1200,2740,26,419,884,2666,1001,564,2382,639,2532,732,1876,1128,831,1057,2224,420,3178,1457,1949,2743,1727,888,1007,1061,2144,...
-0.2569259022510854,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.28661790671407417,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.10549180847782079,0.10549180847782079,-0.0032099369180387514,2.4563975818909127,0.3228367256941829,0.7573020385339275,0.17794870135979338,0.2141739076546943...
3,642
S phase
31
101
2.693082
0.007079
Q9NRF9,P25205,P49721,P41440,P15927,Q9UJX4,P40937,P49736,Q9Y619,P28072,P11802,P20618,Q8WVM7,P28070,P33993,P31751,P60900,Q9BRT9,P17980,Q99436,P25787,Q9NR33,O75832,Q16763,O00231,Q9UJX3,O00487,Q9Y248,P18858,Q9UL46,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
269,882,5,6,875,412,641,644,299,34,784,50,847,62,565,564,568,207,824,621,828,220,449,98,589,770,590,772,729,518,123
589,2839,2113,590,1188,1712,2912,2359,3472,449,2845,784,2021,875,824,729,50,1627,882,1199,828,1628,1722,2925,1126,62,34,1200,1629,2381,1001,564,1002,2607,565,3177,1947,1799,2223,2224,1059,641,1547,6,1727,1007,1062,2031,1131,123,5,644,1462,1207,2307,892,568,1011,1640,1733,1890,1810,1139,2677,1217,2803,1570,1307,2399,349...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.5833007240749342,-0.293180236639351,-1.2729912830023138,0.7573020385339275,-0.5470271646093248,0.4676910964650831,-0.14817681559539894,0.39526806690703153,0.4314806144175144,0.50389952531643,2.70...
3,642
Cell cycle
75
333
2.688001
0.007188
P00374,Q9NRF9,P49721,P41440,P53990,P55735,P61163,P62258,Q9UJX4,Q9H444,Q9BSJ2,Q86XL3,P31946,P67870,P40937,Q9BS16,P42771,Q9Y619,Q14739,O60763,P28072,Q9UPN4,Q96CW5,Q9NXR1,Q9UQ84,Q9NYB0,P30153,Q04917,P20618,O60566,P36873,O95684,Q96IY1,P28070,Q13561,Q8NBT2,Q9Y6D9,Q8NC56,P33993,P31751,Q99640,P41208,P60900,Q9BRT9,O94927,Q1657...
Processes and pathways
Reactome Pathways
msigdb_reactome
0,269,5,6,496,497,498,499,412,671,407,150,639,393,641,156,642,299,31,525,34,442,291,181,310,309,419,532,50,301,420,58,319,62,190,468,65,469,565,564,474,566,568,207,322,613,200,321,86,329,88,221,220,449,621,92,213,345,611,100,98,507,102,589,590,600,596,371,383,518,119,120,606,664,123
1046,589,2839,2113,1707,590,2585,1188,3551,321,2786,345,3333,1433,868,1712,1861,1371,2284,200,2912,2359,2360,301,525,3378,2363,3044,1280,3472,3087,3379,449,102,2725,322,1938,1621,58,3362,2211,596,0,726,3248,1716,1717,2371,872,1196,1870,1051,1376,2845,3135,784,2021,1053,875,600,3175,824,3450,729,1796,877,1719,50,788,145...
0.28661790671407417,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,-0.0032099369180387514,0.6125126132127564,-0.40195737736821424,0.21417390765469435,-1.6727503201710714,0.9382447978183553,-0.5107560674697893,0.9020601005809601,-0.9824776229443855,0.10549180847782079,0.39526806690703153,-0.0032099369180387...
3,642
Tetratricopeptide-like helical domain superfamily [IPR011990]
25
92
2.679015
0.007384
Q9H7B4,Q9H7Z3,Q9UJX4,Q96DB5,Q5R3I4,Q32P28,O75718,P13674,Q96BR5,P49321,O14579,O75153,Q9BQ70,Q13217,P61201,Q6DKK2,A0AVF1,Q96RK4,Q13451,Q96LZ7,Q15006,O00231,Q9Y3D6,Q02790,Q7L5D6
Sequence
InterPro Superfamily
interpro_homologous_superfamily
4,672,412,543,21,280,387,274,540,529,523,48,179,303,302,69,558,206,693,756,610,589,243,369,662
558,988,589,2355,523,2520,1112,2521,1113,1712,1531,3086,48,387,3213,1049,1714,2369,1940,274,2381,1294,2028,2743,1950,529,2974,1301,2467,1210,302,2044,369,1070,836,1071,1648,303,2804,693,2048,2681,610,1654,3422,801,280,21,1154,69,2620,1579,1490,2941,1494,662,2944,1255,2627,540,543,913,1256,756,206,970,2887,1683,1507,179...
0.6487129491004436,0.3228367256941829,0.6125126132127564,-0.293180236639351,0.6849112910125618,-0.36569595808664096,0.2503969717100796,-0.36569595808664096,0.2503969717100796,-0.0032099369180387514,0.06926009468413799,-0.7284199416787922,2.7091423080596084,0.8296849457389607,-0.8372860991952851,0.28661790671407417,-0.0...
3,642
Neddylation
18
81
2.651472
0.008014
P28072,O60826,P49721,O00231,Q9NX08,P60900,Q86X83,Q99627,Q9UBW8,Q16576,P20618,P61201,Q9UL46,Q99436,O75832,Q9H9Q2,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,160,5,589,439,568,430,622,242,613,50,302,518,621,449,219,123,62
589,2839,2113,590,1188,1712,160,1374,449,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,2470,302,1011,1068,3103,1640,1733,1890,1810,1139,1568,2803,1570,2046,2399,1650,1961,1310,3261,3384,1654,2051,3345,3266,3346,2318,613,2481,1405,1243,2407,430,2691,1975,1824,3577,1825,1914,2629,621,1165,6...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,1.44463503950887,0.14172133947363577,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.3...
3,642
Switching of origins to a post replicative state
14
61
2.637968
0.00834
P28072,Q16763,P49721,O00231,O75832,P60900,Q9UJX4,P20618,Q9UL46,Q99436,P28070,P49720,Q9Y619,P33993
Processes and pathways
Reactome Pathways
msigdb_reactome
34,98,5,589,449,568,412,50,518,621,62,123,299,565
589,2839,2113,590,1188,1712,2912,449,824,50,1627,882,1199,828,1628,1722,1126,62,34,1200,2381,1002,2607,565,2224,1727,1007,123,5,644,1207,2307,568,1011,1640,1733,1890,1810,1139,2803,1570,1307,2399,1653,3384,1654,98,1824,2079,621,1165,3305,2514,3307,770,412,3460,2516,518,1523,299
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.5833007240749342,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.03302618423136544,0.39526806690703153,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514...
3,642
Class i mhc mediated antigen processing presentation
11
126
2.636656
0.008373
P28072,Q16763,P49721,P30511,Q13049,Q9NZ08,P20618,Q12834,P55786,P19474,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,98,5,10,43,75,50,119,24,56,62
2645,589,2839,2113,590,1188,2963,1709,483,2911,1712,1192,449,3399,349,1194,3288,3174,1867,2015,3362,2452,2598,2731,2214,783,824,56,50,1873,1199,828,1628,1722,883,491,1126,62,34,1200,3313,1454,2381,10,2224,1727,1007,123,5,1465,1207,687,2036,2307,497,24,1887,3053,256,568,2470,1391,894,1011,3514,1640,1733,1890,1810,1811,2...
-0.43822119087257283,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.6195767634991557,-0.0032099369180387514,0.7211076503875371,-0.5833007240749342,-0.0032099369180387514,0.21417390765469435,0.7573020385339275,-1.0913994610234883,0.9020601005809601,0.214173907654694...
3,642
Anchoring of the basal body to the plasma membrane
16
40
2.621436
0.008756
O15078,O75935,P61163,P62258,Q9UPN4,P41208,Q9NXR1,O94927,P30153,Q15691,O43805,Q14203,Q9H6D7,O95684,Q96CS2,Q13561
Processes and pathways
Reactome Pathways
msigdb_reactome
345,102,498,499,442,566,181,322,419,371,200,329,88,58,92,190
345,200,102,322,58,1716,872,1870,1051,3175,789,419,566,2744,3292,2146,498,1212,499,3255,1892,796,190,2400,329,3295,1313,799,611,371,2404,1155,1582,2873,92,1682,1261,88,181,442
0.9020601005809601,1.299988629982995,1.8784066596115039,0.9382447978183553,2.4563975818909127,-0.0032099369180387514,0.39526806690703153,-0.07568886835881676,0.28661790671407417,-0.8009947951684113,0.4676910964650831,0.7934944666326158,0.6487129491004436,-0.4744874152715812,-0.9098765594461098,-0.18442420720352415,0.72...
3,642
Negative regulation of neuron death
9
44
2.616068
0.008895
Q96EB6,P09601,P48681,P07196,P30511,Q9UMX5,P48507,P09104,Q01105
Processes and pathways
GO Biological process
msigdb_gobp
292,166,224,73,10,16,177,273,213
3043,1116,3213,1790,2968,2124,1869,73,1376,273,166,10,1001,2532,1876,1298,1635,177,224,1802,1462,3180,2034,1882,1640,1956,2750,2978,213,1565,838,841,400,292,1337,2956,3442,2893,671,1689,2515,16,771,556
-0.6921363540246968,0.2503969717100796,-0.8372860991952851,-0.039448282981301534,-0.6195767634991557,-0.18442420720352415,-0.07568886835881676,2.2035770349778274,0.14172133947363577,1.082964630935729,1.4084761139436706,5.7728828739278075,0.3228367256941829,-0.36569595808664096,-0.07568886835881676,0.17794870135979338,0...
3,642
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
27
74
2.613603
0.008959
O43676,P20674,O95139,O75947,P06576,P21912,P14927,P22695,P00846,P56556,Q7L592,P31930,P03886,Q8TB37,O96000,P00403,O95182,P15954,O75380,O14949,O14548,O95167,O75964,P13073,O75438,P24539,P18859
Processes and pathways
Reactome Pathways
msigdb_reactome
136,139,634,388,390,638,391,275,162,645,705,790,49,579,681,560,184,683,79,344,343,595,108,727,234,730,365
1186,2280,343,344,2010,136,2011,1372,1375,993,79,234,1281,871,388,108,634,595,2450,184,2120,681,3400,560,162,49,2729,390,2213,936,1445,727,2022,391,683,365,1288,139,638,275,730,2458,1201,1632,790,791,2137,1950,1299,2611,3179,1953,2038,645,1737,1228,1021,2402,705,1906,2946,1026,2558,579,2885,1167,1921,3411,1515,3445,210...
0.21417390765469435,-0.2569259022510854,0.9020601005809601,0.9020601005809601,-0.14817681559539894,1.5892531387800641,-0.14817681559539894,0.14172133947363577,0.14172133947363577,0.3228367256941829,2.1313283265493896,1.1914848887169478,0.17794870135979338,0.39526806690703153,0.8296849457389607,1.8061284441617231,0.5763...
3,642
Regulation of hmox1 expression and activity
12
50
2.609756
0.009061
P28072,P49721,P09601,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P67870,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,166,589,568,50,518,621,449,393,123,62
589,2839,2113,590,1188,1712,449,166,824,1719,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,1810,393,1137,3383,1139,2803,1570,2399,1961,3261,3384,1654,2820,1824,621,1165,3497,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,0.7573020385339275,1.4084761139436706,0.4314806144175144,-0.0032099369180387514,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.250396971710079...
3,642
Cellular response to chemical stress
19
82
2.606843
0.009138
P49721,P20674,Q9BZK7,P67870,P28072,P09601,P20618,P28070,P00403,P07237,P60900,P30519,Q99436,O75832,Q16881,O00231,O14548,Q9UL46,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
5,139,548,393,34,166,50,62,560,562,568,325,621,449,505,589,343,518,123
589,2839,2113,2280,590,343,1188,1712,1372,449,871,1283,3400,560,2124,562,166,936,1445,727,683,824,1719,50,139,1199,828,1628,1722,1126,62,34,1200,2222,1874,1453,325,2606,733,2224,3178,1950,1727,1007,123,5,1207,2799,2307,568,1011,1640,1733,1890,1810,393,1137,3383,1139,2803,1570,2399,1961,3261,3384,1654,2548,505,1321,2558...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,-0.2569259022510854,0.6125126132127564,0.9020601005809601,0.21417390765469435,-0.0032099369180387514,0.14172133947363577,0.7573020385339275,0.39526806690703153,0.17794870135979338,-1.0913994610234883,0.6487129491004436,-0.18442420720352415,0.6487129491004436,1...
3,642
Regulation of mrna stability by proteins that bind au rich elements
14
66
2.600451
0.00931
Q92945,P28072,P49721,O00231,O00487,P60900,P20618,Q9NQT5,Q9UL46,Q99436,O75832,P49720,Q01105,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
512,34,5,589,590,568,50,550,518,621,449,123,213,62
589,2839,2113,590,1188,2786,1712,449,2014,1446,785,824,50,1199,828,1628,1722,1126,62,34,1200,1001,639,2383,2224,1456,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,1471,213,1565,3383,1645,1139,2803,2805,1572,3384,1654,2313,1485,1080,1317,1824,512,1162,2628,621,1165,1600,977,2830,550,518,1523,2109,3041
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.5107560674697893,-0.0032099369180387514,0.7573020385339275,-0.14817681559539894,0.10549180847782079,0.4676910964650831,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0...
3,642
Amide binding
12
118
2.598917
0.009352
P00374,Q9Y680,Q15392,Q9UM22,P41440,P26885,P30511,Q9NZ08,Q96AY3,P55786,P30533,P62942
Functions
GO Molecular function
msigdb_gomf
0,101,3,35,6,103,10,75,54,24,117,60
2783,1365,773,1934,2584,3571,2115,3471,3132,253,483,2648,3416,446,724,2843,1714,0,3636,2452,2598,2371,3462,3513,1376,350,2292,783,3363,3546,2023,2126,3251,2793,2297,2530,881,103,883,2848,2133,1631,10,117,3488,2383,1725,314,2928,6,3401,2305,3340,1460,2930,494,3252,2974,1301,1803,2035,1805,2853,24,1557,3514,1067,60,1956,...
-0.5107560674697893,0.14172133947363577,0.4676910964650831,-0.11193170763769089,-0.40195737736821424,-1.8545831244298248,-0.18442420720352415,-1.2729912830023138,-0.7647060824085025,1.1191399017046813,0.7211076503875371,-0.43822119087257283,-1.127712223754586,0.7573020385339275,0.50389952531643,-0.5470271646093248,-0.0...
3,642
Mitochondrial protein import
9
37
2.593779
0.009493
Q8N4H5,O60830,Q9Y5L4,Q9NX63,Q5JRX3,Q13505,Q99595,Q9NS69,Q9Y5J9
Processes and pathways
Reactome Pathways
msigdb_reactome
228,33,340,208,331,203,22,55,122
1859,1048,33,2650,3172,1713,3133,1714,1793,390,2213,2217,3475,3015,2793,2458,2385,2670,837,203,1484,1902,331,228,22,2084,1420,55,208,2712,2961,1527,2517,588,1183,122,340
-0.07568886835881676,0.28661790671407417,3.286571983805788,-0.43822119087257283,-0.8009947951684113,-0.0032099369180387514,-0.7647060824085025,-0.0032099369180387514,-0.039448282981301534,0.8296849457389607,-0.2206738976316064,-0.2206738976316064,-1.2729912830023138,-0.6558553007676541,-0.5107560674697893,-0.3294369165...
3,642
Negative regulation of cell population proliferation
24
112
2.59097
0.009571
Q15392,Q9NR77,O43324,Q32P28,P67870,O94788,Q01664,Q71SY5,Q9Y366,P09601,Q13049,Q96G23,P09493,Q9Y4G8,Q8IZP0,Q9Y6D9,Q13043,O14737,Q96DY7,P98175,Q53EL6,P57105,P22466,O14745
Processes and pathways
GO Biological process
msigdb_gobp
3,267,384,280,393,28,395,164,443,166,43,44,174,198,193,65,188,183,77,104,226,118,246,359
2198,183,359,2283,819,1431,384,990,415,3545,28,1788,726,2124,1717,3573,1196,174,166,997,487,823,2920,2294,1626,246,2378,2458,2738,3547,1056,1455,1876,1128,606,3178,1457,1949,642,891,1388,1389,1808,118,3052,3255,393,501,104,2043,738,395,1896,3548,1217,1071,534,3621,1219,188,43,3021,2472,1018,950,1739,655,1399,1964,1965,...
-0.2206738976316064,1.3361529184365946,0.8658734867848911,-0.2569259022510854,0.4314806144175144,0.10549180847782079,0.8296849457389607,0.3228367256941829,0.7934944666326158,-1.6363933493954572,3.5390831401508613,-0.039448282981301534,0.50389952531643,-0.18442420720352415,-0.0032099369180387514,-1.8545831244298248,0.21...
3,642
Protein transmembrane transport
10
31
2.590314
0.009589
O95831,O60830,Q07820,O75298,Q15629,Q86WA8,P11274,Q99595,Q9NS69,O00189
Processes and pathways
GO Biological process
msigdb_gobp
64,33,187,448,426,577,175,22,55,481
481,1859,1048,33,448,2649,1714,64,1793,2217,175,564,943,1301,1887,3053,1557,3514,187,3107,1484,426,1902,577,2690,1919,22,1420,55,1772,2517
0.7211076503875371,-0.07568886835881676,0.28661790671407417,3.286571983805788,0.7573020385339275,-0.43822119087257283,-0.0032099369180387514,2.348055342926024,-0.039448282981301534,-0.2206738976316064,1.3723154099889678,0.6487129491004436,0.3590534415201943,0.17794870135979338,-0.07568886835881676,-0.6921363540246968,0...
3,642
Outer membrane
18
101
2.581844
0.009827
Q8N2A8,Q8N4H5,Q07820,O75323,P09601,O00165,Q99720,Q9NX63,Q9Y3D6,Q13505,Q9UBM7,Q9GZY8,Q8IWB1,P57105,Q9NS69,O60313,Q8N0X7,Q9HCL2
Localization
GO Cellular component
msigdb_gocc
99,228,187,165,166,72,9,208,243,203,284,51,23,118,55,90,194,30
72,773,1110,3571,1434,90,2721,165,3172,1714,1788,3045,1793,3088,2374,2453,166,2376,2846,2793,3547,1295,420,2385,2743,1950,3340,891,2391,1729,1952,118,3183,187,3366,203,1483,1484,801,2981,1315,3296,2939,844,2405,957,3111,1241,2408,23,2409,2252,194,99,228,2764,3503,2491,2561,2414,1756,3116,3604,2080,852,1831,970,1339,116...
2.2035770349778274,0.4676910964650831,0.2503969717100796,-1.8545831244298248,0.10549180847782079,1.986811502084436,-0.4744874152715812,1.4084761139436706,-0.8009947951684113,-0.0032099369180387514,-0.039448282981301534,-0.6921363540246968,-0.039448282981301534,-0.7284199416787922,-0.293180236639351,-0.32943691658390756...
3,642
Separation of sister chromatids
27
118
2.571672
0.010121
P49721,P55735,Q9UJX4,Q9BS16,P28072,Q9NXR1,P30153,P20618,O60566,P36873,Q96IY1,P28070,Q8NBT2,Q9Y6D9,P60900,Q9H3R5,Q99436,O75832,Q96EA4,Q16763,O00231,Q6P1K2,O00487,Q15691,Q9UL46,Q12834,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
5,497,412,156,34,181,419,50,301,420,319,62,468,65,568,86,621,449,100,98,589,507,590,371,518,119,123
1046,589,2839,2113,590,1188,2786,868,1712,1861,2284,2359,301,3044,449,1716,824,50,1199,828,1628,1722,1126,62,34,1200,419,884,2381,2224,420,2744,1727,2225,1007,123,5,2974,2466,1207,2853,3292,2307,497,1639,568,1011,1640,1733,1890,3255,1892,1069,1139,3404,119,2803,1221,1018,796,1652,2400,3295,1741,2049,3384,2050,1654,371,...
0.28661790671407417,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.5107560674697893,0.39526806690703153,-0.0032099369180387514,-0.07568886835881676,-0.2569259022510854,-0.293180236639351,1.0106084847967511,-0.6921363540246968,0.7573020385339275,-0.00320993691803875...
3,642
Rotamase
11
24
2.56288
0.010381
Q9Y680,Q00688,Q9NWM8,P26885,Q13427,Q13451,Q9Y3C6,Q9Y237,Q96AY3,Q02790,P62942
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
101,609,71,103,692,693,382,381,54,369,60
2648,2530,103,2133,1631,2305,60,609,369,836,692,693,1072,2048,2160,750,54,2257,1034,71,1694,381,382,101
-0.43822119087257283,-0.36569595808664096,1.8784066596115039,-0.18442420720352415,0.03302618423136544,-0.2569259022510854,2.4202850586689473,0.6125126132127564,0.8658734867848911,0.4314806144175144,0.5401059130940894,0.5401059130940894,0.28661790671407417,-0.14817681559539894,-0.18442420720352415,0.50389952531643,2.564...
3,642
M phase
54
218
2.559007
0.010497
P49721,P53990,P55735,P61163,P62258,Q9UJX4,Q9BSJ2,Q86XL3,P67870,Q9BS16,Q14739,O60763,P28072,Q9UPN4,Q96CW5,Q9NXR1,P30153,P20618,O60566,P36873,O95684,Q96IY1,P28070,Q13561,Q8NBT2,Q9Y6D9,Q8NC56,P41208,P60900,O94927,O43805,Q9H3R5,Q99436,Q9H6D7,Q14203,O75832,Q96CS2,Q01105,O15078,Q15154,Q96EA4,Q16763,O00231,O75935,O00487,P1610...
Processes and pathways
Reactome Pathways
msigdb_reactome
5,496,497,498,499,412,407,150,393,156,31,525,34,442,291,181,419,50,301,420,58,319,62,190,468,65,469,566,568,322,200,86,621,88,329,449,92,213,345,611,100,98,589,102,590,600,507,371,383,518,119,606,664,123
1046,589,2839,2113,590,1188,2786,345,3333,868,1712,1861,1371,2284,200,2359,301,525,3044,3087,3379,449,102,322,1938,1621,58,726,1716,872,1870,1051,1053,600,3175,824,3450,1719,50,788,789,1199,828,1628,1722,2379,1126,62,34,1200,2740,419,884,2381,2383,2224,420,606,566,1634,886,3096,2744,1727,2225,1007,123,5,3252,2974,891,2...
0.28661790671407417,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.5107560674697893,0.9020601005809601,-0.9824776229443855,0.39526806690703153,-0.0032099369180387514,-0.07568886835881676,0.14172133947363577,-0.2569259022510854,1.299988629982995,-0.293180236639351,1...
3,642
Predicted secreted proteins
13
64
2.557982
0.010528
Q9UM22,Q07021,Q8WUJ1,Q15165,Q9H6E4,P80303,Q9NZ08,P07942,Q9UMX5,Q02818,P04083,O60888,P22466
Functions
Protein Atlas Protein class
protein_atlas_protein_class
35,186,7,8,170,11,75,109,16,15,236,52,246
3599,3043,723,52,387,2651,362,994,3616,236,3573,1869,2917,109,2214,3363,2601,599,2023,937,246,2530,324,2973,734,1882,3220,1884,3620,3018,11,3591,257,15,186,3476,1219,1142,2475,8,701,2483,704,467,1086,3575,963,7,1913,1331,1254,1412,3390,3468,3037,1416,3498,170,975,3554,75,35,16,2781
-2.218500306818185,-0.6921363540246968,0.50389952531643,2.6008322724488426,0.8296849457389607,-0.43822119087257283,0.8658734867848911,0.3228367256941829,-2.6556413424811107,1.1914848887169478,-1.8545831244298248,-0.07568886835881676,-0.5833007240749342,1.8061284441617231,-0.2206738976316064,-1.0187821821884444,-0.40195...
3,642
Condensed chromosome centromeric region
23
85
2.556535
0.010572
Q9UEE9,P55735,Q9NZZ3,Q9BS16,Q9UFC0,Q9NXR1,O60566,P36873,Q96IY1,Q13185,Q13561,Q8NBT2,Q9Y6D9,Q96DY7,O14974,Q9H3R5,Q14203,Q96EA4,Q6P1K2,O75935,Q9Y448,Q9Y3E7,Q8NFH3
Localization
GO Cellular component
msigdb_gocc
133,497,552,156,159,181,301,420,319,573,190,468,65,77,321,86,329,100,507,102,244,383,664
321,2786,868,1861,1371,2284,301,3044,102,1538,1053,2028,420,3096,2744,1130,2225,2386,1061,2466,2853,3292,497,1639,3255,3257,1069,3404,2544,573,1221,1307,190,2400,1398,329,1741,1898,2050,1313,2157,1314,1150,507,958,1582,2818,1820,2066,468,664,805,2072,2697,1976,1253,2079,77,100,1029,2988,319,2990,2767,1982,2334,156,2998...
0.9382447978183553,-0.5107560674697893,0.39526806690703153,-0.07568886835881676,0.14172133947363577,-0.2569259022510854,1.0106084847967511,-0.6921363540246968,1.8784066596115039,0.06926009468413799,0.28661790671407417,-0.14817681559539894,0.7934944666326158,-0.7284199416787922,-0.4744874152715812,0.2503969717100796,-0....
3,642
Cytoprotection by hmox1
17
72
2.521601
0.011682
P28072,P00403,P49721,P09601,O00231,O14548,P60900,P20674,P30519,Q9BZK7,P20618,Q9UL46,Q99436,O75832,P67870,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,560,5,166,589,343,568,139,325,548,50,518,621,449,393,123,62
589,2839,2113,2280,590,343,1188,1712,1372,449,871,3400,560,166,936,1445,727,683,824,1719,50,139,1199,828,1628,1722,1126,62,34,1200,325,733,2224,3178,1950,1727,1007,123,5,1207,2799,2307,568,1011,1640,1733,1890,1810,393,1137,3383,1139,2803,1570,2399,1961,3261,3384,1654,2548,1321,2558,2820,1824,2885,2767,621,1165,3497,548...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,-0.2569259022510854,0.6125126132127564,0.9020601005809601,0.21417390765469435,-0.0032099369180387514,0.14172133947363577,0.7573020385339275,0.39526806690703153,-1.0913994610234883,0.6487129491004436,1.4084761139436706,0.3590534415201943,0.10549180847782079,0.5...
3,642
Primary mitochondrial disease
29
109
2.515932
0.011872
Q9UMS0,Q5JPH6,P52815,O43676,P20674,Q70HW3,Q9H3H1,P14927,P22695,P00846,P56556,Q8NFF5,Q7LG56,Q5JTZ9,P03886,Q8TB37,O95831,P00403,Q07021,Q6DKK2,O75380,Q9BQT8,O60313,P39210,Q9NWS8,O14949,Q96CU9,Q9UGM6,Q9Y2R0
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
134,401,495,136,139,17,282,391,275,162,645,709,429,575,49,579,64,560,186,69,79,624,90,212,251,344,374,515,121
1186,2280,344,136,2011,1372,90,1375,993,79,1281,2012,871,2120,64,3400,560,162,49,2729,2733,2213,2918,1795,3475,727,391,1288,139,275,2458,1201,1632,212,1950,1877,1299,1063,3179,495,1208,833,645,736,1474,1476,186,2402,3296,401,575,1233,2059,3483,844,69,2814,17,1320,2321,429,1906,707,2946,1026,747,709,1669,579,1911,1915,3...
0.21417390765469435,-0.2569259022510854,0.9020601005809601,1.5892531387800641,-0.14817681559539894,0.14172133947363577,1.986811502084436,0.14172133947363577,0.3228367256941829,2.1313283265493896,0.17794870135979338,-0.14817681559539894,0.39526806690703153,-0.18442420720352415,2.348055342926024,-1.0913994610234883,0.648...
3,642
Ub specific processing proteases
7
80
2.504736
0.012254
P28072,P49721,Q9UPT9,P20618,Q12834,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,144,50,119,123,62
589,2839,2113,590,1188,819,1712,2587,385,2447,449,1714,3429,1717,2023,824,50,2793,1199,828,1628,1722,1126,62,34,1200,2532,2224,2303,1727,3340,1878,1007,123,5,1207,167,1806,2307,568,1011,1640,1733,1890,1139,119,2860,2803,1570,2311,3261,2048,1965,2980,3384,1654,1484,2054,2317,803,2252,1824,1499,3033,849,2500,2332,2333,62...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,0.4314806144175144,-0.0032099369180387514,-0.40195737736821424,0.8296849457389607,-0.32943691658390756,0.7573020385339275,-0.0032099369180387514,-1.1640277646940118,-0.0032099369180387514,-0.14817681559539894,0.4314806144...
3,642
EF-hand domain [IPR002048]
11
50
2.502706
0.012325
Q9Y680,Q9NWM8,Q9NZM3,P80303,O43852,Q02818,Q14257,Q96AY3,P0DP25,Q8NI22,Q9BRK5
Sequence
InterPro Domain
interpro_domain
101,71,106,11,78,15,80,54,85,61,132
445,78,3598,2207,3133,1441,2653,1718,85,488,2658,417,1625,2735,1383,1056,566,686,1800,893,11,15,3294,370,80,2756,1020,163,3347,1661,2409,2252,3517,2948,61,54,1500,3494,3578,132,377,716,1767,71,106,813,3635,2712,1933,101
0.7573020385339275,2.1313283265493896,-2.182093097988025,-0.2206738976316064,-0.7647060824085025,0.10549180847782079,-0.43822119087257283,-0.0032099369180387514,2.059073169203502,0.7211076503875371,-0.43822119087257283,0.7934944666326158,0.03302618423136544,-0.4744874152715812,0.14172133947363577,0.28661790671407417,0....
3,642
Mapk6 mapk4 signaling
12
49
2.499202
0.012447
P28072,P49721,O00231,O00487,P60900,P20618,P25685,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,590,568,50,602,518,621,449,123,62
589,2839,2113,590,1188,2786,1712,449,872,3175,824,50,602,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,568,1731,1011,1640,1733,1890,3106,1139,652,2803,3384,1654,1314,2936,1824,621,1165,2340,1175,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.5107560674697893,-0.0032099369180387514,0.7573020385339275,0.39526806690703153,-0.8009947951684113,0.4314806144175144,2.7091423080596084,0.6125126132127564,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0....
3,642
Abc transporter disorders
11
47
2.496013
0.01256
Q13438,P28072,P49721,O00231,P60900,P20618,Q9UL46,Q99436,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
189,34,5,589,568,50,518,621,449,123,62
589,2839,2113,590,721,1188,1712,1533,449,1282,824,50,1199,828,1628,1722,1126,62,34,1200,2224,1727,1007,123,5,1207,2307,1466,568,1011,1640,1733,1890,1139,2803,189,3384,1654,1824,621,1165,2771,718,3602,1359,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.50389952531643,0.21417390765469435,-0.0032099369180387514,0.06926009468413799,0.7573020385339275,0.17794870135979338,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0....
3,642
EF-hand domain pair [IPR011992]
11
55
2.486739
0.012892
Q9Y680,Q9NWM8,Q9NZM3,P80303,O43852,Q02818,Q14257,Q96AY3,P0DP25,Q8NI22,Q9BRK5
Sequence
InterPro Superfamily
interpro_homologous_superfamily
101,71,106,11,78,15,80,54,85,61,132
445,78,3598,2207,3133,1441,2653,1718,85,488,2658,417,1625,2735,1383,1056,566,686,1800,941,893,2039,11,15,3294,370,80,2756,1020,163,3347,1661,1085,2409,2252,3517,2876,2948,61,54,1500,3494,3578,132,377,716,1767,809,71,106,813,3635,2712,1933,101
0.7573020385339275,2.1313283265493896,-2.182093097988025,-0.2206738976316064,-0.7647060824085025,0.10549180847782079,-0.43822119087257283,-0.0032099369180387514,2.059073169203502,0.7211076503875371,-0.43822119087257283,0.7934944666326158,0.03302618423136544,-0.4744874152715812,0.14172133947363577,0.28661790671407417,0....
3,642
Regulation of plk1 activity at g2 m transition
17
42
2.482554
0.013044
O15078,O75935,P61163,P62258,Q9UPN4,P41208,Q9NXR1,O94927,P30153,Q15691,O43805,O14974,Q14203,Q9H6D7,O95684,Q96CS2,Q13561
Processes and pathways
Reactome Pathways
msigdb_reactome
345,102,498,499,442,566,181,322,419,371,200,321,329,88,58,92,190
3551,321,345,200,102,322,58,1716,872,1870,1051,3175,789,419,566,2744,3292,2146,498,1212,2147,499,3255,1810,1892,796,190,2399,2400,329,3295,611,371,2404,1582,2873,92,1682,1261,88,181,442
-1.6727503201710714,0.9382447978183553,0.9020601005809601,1.299988629982995,1.8784066596115039,0.9382447978183553,2.4563975818909127,-0.0032099369180387514,0.39526806690703153,-0.07568886835881676,0.28661790671407417,-0.8009947951684113,0.4676910964650831,0.7934944666326158,0.6487129491004436,-0.4744874152715812,-0.909...
3,642
Protein peptidyl prolyl isomerization
12
29
2.475211
0.013316
Q9Y680,Q00688,Q9NWM8,P26885,Q13427,Q13451,Q9Y3C6,Q6UX04,Q9Y237,Q96AY3,Q02790,P62942
Processes and pathways
GO Biological process
msigdb_gobp
101,609,71,103,692,693,382,703,381,54,369,60
988,2648,2530,103,2133,1631,2305,2974,60,609,369,836,1222,692,693,1072,2048,2160,1402,703,750,54,2257,1034,71,1694,381,382,101
0.3228367256941829,-0.43822119087257283,-0.36569595808664096,1.8784066596115039,-0.18442420720352415,0.03302618423136544,-0.2569259022510854,-0.6195767634991557,2.4202850586689473,0.6125126132127564,0.8658734867848911,0.4314806144175144,0.21417390765469435,0.5401059130940894,0.5401059130940894,0.28661790671407417,-0.14...
3,642
Apc c mediated degradation of cell cycle proteins
14
59
2.465118
0.013697
P28072,Q16763,P49721,O00231,P60900,Q9UJX4,P20618,O60566,Q99436,Q9UL46,O75832,Q12834,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,98,5,589,568,412,50,301,621,518,449,119,123,62
589,2839,2113,590,1188,3551,1712,2284,301,449,872,824,50,1627,1199,828,1628,1722,1126,62,34,1200,2381,2224,1727,1007,123,5,1207,3292,2307,568,1011,1640,1733,1890,1810,1139,119,2803,1221,1570,2399,3384,1654,98,1824,2079,2988,621,1165,3305,3307,770,412,3460,2516,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-1.6727503201710714,-0.0032099369180387514,-0.2569259022510854,1.0106084847967511,0.7573020385339275,0.39526806690703153,0.4314806144175144,2.7091423080596084,0.03302618423136544,0.21417390765469435,0.4314806144175144,0.0...
3,642
Microtubule organizing center
60
235
2.464191
0.013732
Q9Y496,Q13432,P41440,P53990,P61163,Q15555,Q9BSJ2,P16219,P08670,Q9UFC0,O60763,Q9UNZ2,Q9UJC3,Q9Y366,Q9H981,Q86SX3,Q9UPN4,Q96CW5,Q9NXR1,Q5SW79,O60566,O95684,P28070,Q86UY6,Q13561,Q9Y6D9,Q9UIJ7,Q6DKK2,P41208,A0AVF1,Q96RK4,O94927,Q14498,O43805,O14974,P0DP25,Q9UPT5,Q9H6D7,Q14203,Q9Y5Y2,Q96CS2,Q9Y5K6,O15078,Q15154,Q96EA4,O7593...
Localization
GO Cellular component
msigdb_gocc
677,129,6,496,498,399,407,637,148,159,525,296,294,443,40,169,442,291,181,304,301,58,62,191,190,65,339,69,566,558,206,322,463,200,321,85,629,88,329,252,92,630,345,611,100,102,600,378,592,106,244,522,238,113,371,233,119,606,363,487
558,1046,2281,1782,3551,321,345,868,2358,200,592,776,301,1439,525,233,3044,1374,1280,1863,3472,3012,680,102,2119,322,58,3362,363,1717,2915,872,1196,148,2020,997,85,487,3135,1942,2021,998,787,600,637,3175,1943,789,1627,882,1199,2795,2531,62,1200,2740,829,2381,1001,732,1876,1129,1724,2136,606,3140,2304,566,6,2744,643,222...
0.6487129491004436,0.28661790671407417,-0.2569259022510854,-0.039448282981301534,-1.6727503201710714,0.9382447978183553,0.9020601005809601,0.39526806690703153,-0.293180236639351,1.299988629982995,0.6125126132127564,0.4676910964650831,1.0106084847967511,0.10549180847782079,0.6849112910125618,1.1914848887169478,-0.692136...
3,642
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
6
52
2.464092
0.013736
P28072,Q16763,P49721,P20618,Q12834,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,98,5,50,119,62
589,2839,2113,590,1188,3551,1712,449,824,50,1199,828,1628,1722,1126,62,34,1200,2381,2224,1727,1007,123,5,1207,3292,2307,568,1011,1640,1733,1890,1139,119,2803,1570,3384,1654,98,1824,2079,2988,621,1165,3305,3307,770,412,3460,2516,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-1.6727503201710714,-0.0032099369180387514,0.7573020385339275,0.4314806144175144,2.7091423080596084,0.21417390765469435,0.4314806144175144,0.03302618423136544,-0.0032099369180387514,0.2503969717100796,2.384170981359444,3....
3,642
Antigen processing ubiquitination proteasome degradation
9
98
2.459398
0.013917
P28072,Q16763,P49721,Q13049,P20618,Q12834,P55786,P19474,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,98,5,43,50,119,24,56,62
2645,589,2839,2113,590,1188,2911,1712,449,3399,349,3288,3174,3362,824,56,50,1873,1199,828,1628,1722,1126,62,34,1200,3313,2381,2224,1727,1007,123,5,1207,687,2307,24,256,568,2470,1391,894,1011,1640,1733,1890,1810,1811,1139,119,43,2803,1570,1649,2399,1650,1961,3188,1480,3261,2862,3384,1654,3345,3266,3346,1656,98,3061,3027...
-0.43822119087257283,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.5833007240749342,-0.0032099369180387514,0.7573020385339275,-1.0913994610234883,0.9020601005809601,-0.9098765594461098,-0.8009947951684113,-1.0187821821884444,0.4314806144175144,2.4925085579988733,2...
3,642
Global genome nucleotide excision repair gg ner
14
46
2.450049
0.014284
P18887,Q9NRF9,Q9H9Q2,P41440,Q9H981,P41208,Q99627,Q9UBW8,Q92759,P61201,Q9NR33,P61956,P40937,P54727
Processes and pathways
Reactome Pathways
msigdb_reactome
489,269,219,6,40,566,622,242,372,302,220,423,641,688
2526,1285,2021,875,2456,729,489,1450,2026,2925,1629,1385,3177,1947,1799,2223,641,1547,566,6,1062,1300,688,892,894,302,423,2677,1568,1310,2318,1405,3113,372,1825,622,1168,40,219,220,269,242,2515,1361,2906,2274
-0.36569595808664096,0.17794870135979338,-0.14817681559539894,0.39526806690703153,-0.32943691658390756,0.50389952531643,0.7211076503875371,0.10549180847782079,-0.14817681559539894,-0.5833007240749342,0.03302618423136544,0.14172133947363577,-0.8009947951684113,-0.11193170763769089,-0.039448282981301534,-0.22067389763160...
3,642
Response to organic cyclic compound
25
189
2.448239
0.014356
P00374,Q9H7B4,P49721,P41440,Q9P1Z2,P07099,Q13126,O15173,P09104,O94788,Q96EB6,P48507,Q9Y4G8,O95831,P07196,P26583,P0DP25,Q01130,O94874,Q15650,P04083,O75116,Q02790,Q9UER7,O14745
Processes and pathways
GO Biological process
msigdb_gobp
0,4,5,6,410,13,18,147,273,28,292,177,198,64,73,324,85,97,349,238,236,233,369,120,359
2646,2198,3571,1187,2840,359,3480,1431,147,1784,1439,559,233,2447,1864,933,1117,934,2119,28,2651,1714,349,2592,64,2017,3502,2211,0,2968,236,2124,2371,2372,3573,872,995,1869,1196,13,73,2599,1376,2020,273,2655,1285,997,85,3363,1446,1942,784,2021,3538,527,3580,787,3617,684,2295,2126,3175,1541,2128,1944,1381,3539,2457,2458...
-0.43822119087257283,-0.2206738976316064,-1.8545831244298248,0.21417390765469435,-0.5470271646093248,0.8658734867848911,-1.309318164869637,0.10549180847782079,1.516947591835183,-0.039448282981301534,0.10549180847782079,0.6487129491004436,1.1914848887169478,-0.32943691658390756,-0.07568886835881676,0.3590534415201943,0....
3,642
Positive regulation of cytokine production
16
67
2.446482
0.014426
Q9NUQ9,Q9NRA0,Q9UJZ1,Q96EB6,P41440,P09601,P30511,Q13049,P26583,P04083,O75787,O75116,P23396,P14373,P78536,Q02952
Processes and pathways
GO Biological process
msigdb_gobp
270,268,295,292,6,166,10,43,324,236,235,233,176,450,351,459
2281,1368,1709,2587,724,559,233,235,2119,1714,2018,236,1868,2598,3573,1051,2214,166,997,2217,3363,599,450,2846,1626,176,324,2132,10,1128,3140,3178,6,1949,943,896,351,2752,650,3560,459,3019,3344,43,460,2311,1399,1080,1241,1331,1672,2496,1028,2077,292,3276,2956,3467,1260,1686,2894,3075,268,2897,270,2346,295
-0.2569259022510854,0.14172133947363577,-0.0032099369180387514,-0.40195737736821424,0.50389952531643,0.6487129491004436,1.1914848887169478,1.1914848887169478,-0.18442420720352415,-0.0032099369180387514,-0.14817681559539894,1.1914848887169478,-0.07568886835881676,-0.40195737736821424,-1.8545831244298248,0.28661790671407...
3,642
Cell cycle checkpoints
39
154
2.443684
0.014538
P49721,P55735,P62258,Q9UJX4,P31946,P40937,P42771,Q9BS16,Q9Y619,P28072,Q9NXR1,Q04917,Q9UQ84,P30153,P20618,O60566,P36873,Q96IY1,P28070,P33993,Q8NBT2,Q9Y6D9,Q99640,P60900,Q9H3R5,Q99436,O75832,Q96EA4,Q16763,O00231,Q6P1K2,O00487,O96028,Q15691,Q9UL46,Q12834,P16104,Q8NFH3,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
5,497,499,412,639,641,642,156,299,34,181,532,310,419,50,301,420,319,62,565,468,65,474,568,86,621,449,100,98,589,507,590,596,371,518,119,600,664,123
1046,589,2839,2113,1707,590,1188,2786,868,1712,1861,2284,2912,301,2363,3044,3472,449,3362,2211,596,1717,872,875,600,824,50,1627,882,1199,828,1628,1722,1382,2925,1126,62,34,1200,419,884,2381,639,1002,2607,565,3177,1947,1799,2224,420,3140,641,1547,642,2744,1727,2225,1007,123,5,644,2974,890,2466,1207,2853,3292,2231,2307,4...
0.28661790671407417,0.6125126132127564,-0.5470271646093248,-0.18442420720352415,-0.0032099369180387514,0.6125126132127564,0.21417390765469435,-0.5107560674697893,0.39526806690703153,-0.0032099369180387514,-0.07568886835881676,-0.2569259022510854,-0.5833007240749342,1.0106084847967511,-0.293180236639351,-0.6921363540246...
3,642
Electron transport chain oxphos system in mitochondria
25
59
2.439875
0.014692
O43676,P20674,O95139,O75947,P06576,P21912,P14927,P22695,P00846,P56556,P31930,P03886,O96000,P00403,O95182,P15954,O75380,O14949,O14548,O95167,O75964,P13073,O75438,P24539,P18859
Processes and pathways
WikiPathways
msigdb_wp
136,139,634,388,390,638,391,275,162,645,790,49,681,560,184,683,79,344,343,595,108,727,234,730,365
1186,2280,343,344,2010,136,2011,1375,993,79,234,1281,871,388,108,634,595,2450,184,2120,681,3400,560,162,49,2729,3089,390,936,1445,3475,3015,727,3136,391,683,365,1288,139,638,275,730,2458,1201,1632,790,791,1299,2611,3179,1953,2038,645,1021,2402,1320,1043,1270,2519
0.21417390765469435,-0.2569259022510854,0.9020601005809601,0.9020601005809601,-0.14817681559539894,1.5892531387800641,-0.14817681559539894,0.14172133947363577,0.3228367256941829,2.1313283265493896,1.1914848887169478,0.17794870135979338,0.39526806690703153,0.8296849457389607,1.8061284441617231,0.5763102717789569,0.61251...
3,642
Fc epsilon receptor fceri signaling
12
55
2.432478
0.014996
P28072,P49721,O00231,O00487,P60900,P20618,Q9UL46,Q99436,P62993,O75832,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,589,590,568,50,518,621,278,449,123,62
589,2839,2113,590,1188,2963,1709,1712,2587,821,449,824,2735,50,1199,828,1628,1722,2379,1126,62,34,1200,2740,2224,1727,1007,123,5,1207,2307,568,894,1011,1640,1733,1890,278,3106,1810,1139,2238,652,2803,1649,2399,3384,1654,2054,2936,1824,621,1165,518,1523
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.6195767634991557,-0.0032099369180387514,-0.0032099369180387514,-0.40195737736821424,0.4314806144175144,0.7573020385339275,0.4314806144175144,-0.4744874152715812,2.7091423080596084,0.21417390765469435,0.4314806144175144...
3,642
Protein targeting
36
132
2.432112
0.015011
Q9H444,Q9H9H4,P62258,O60725,Q86VX9,Q99595,P55786,P31946,O95429,O60830,Q15629,Q86WA8,Q9GZY8,Q9NS69,Q9Y5J6,P40855,O95831,Q13438,Q9Y5L4,P31751,O14737,O00165,Q5JRX3,P43307,Q9Y2T2,Q9H0F7,Q8N4H5,P49257,P46379,Q9Y3D6,O14908,Q9UNL2,P57105,Q9Y5J9,O00189,Q7L5D6
Processes and pathways
GO Biological process
msigdb_gobp
671,673,499,137,149,22,24,639,161,33,426,577,51,55,588,314,64,189,340,564,183,72,331,202,222,625,228,455,96,243,482,380,118,122,481,662
3360,72,988,481,2279,3448,3310,183,482,1859,819,1048,1114,1531,137,33,2649,1713,1049,1714,1788,3174,161,2122,64,1793,1051,2970,2600,2217,3363,1446,3607,1719,879,3138,1382,2795,3547,1384,564,639,1798,2029,1725,314,202,96,455,2390,1008,1301,2032,1465,24,118,1887,3053,1134,1557,3514,1212,499,1213,1471,1811,2978,837,1016,1...
-1.0187821821884444,2.2035770349778274,0.3228367256941829,0.7211076503875371,-0.2569259022510854,-1.2003461062830174,-0.9461757556124973,1.3361529184365946,0.7211076503875371,-0.07568886835881676,0.4314806144175144,0.28661790671407417,0.2503969717100796,0.06926009468413799,1.5892531387800641,3.286571983805788,-0.438221...
3,642
Regeneration
6
36
2.428446
0.015164
P00374,P09601,P07196,P10586,Q96G23,Q7Z4V5
Processes and pathways
GO Biological process
msigdb_gobp
0,166,73,138,44,145
2198,2840,3551,0,236,2371,872,73,166,138,2601,3618,2021,3538,1719,1944,3547,2382,1455,1459,2391,1805,3052,1555,1393,1896,2238,653,2548,1901,2981,145,1911,44,475,1598
-0.2206738976316064,-0.5470271646093248,-1.6727503201710714,9.69022063780281,1.1914848887169478,-0.293180236639351,0.39526806690703153,2.2035770349778274,1.4084761139436706,1.5892531387800641,-0.40195737736821424,-2.6920900992839396,-0.14817681559539894,-1.5636887670185675,-0.0032099369180387514,-0.11193170763769089,-1...
3,642
Deubiquitination
8
98
2.425937
0.015269
P28072,P49721,Q9H981,Q9UPT9,P20618,Q12834,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,40,144,50,119,123,62
589,2839,2113,590,1188,819,2521,1712,2587,385,2447,449,1714,3429,1790,2526,1717,872,2023,824,50,2793,2026,1199,828,1628,1722,1126,62,34,1200,2532,2224,3140,2303,1727,3340,1878,1007,123,5,2229,1207,167,1806,688,2307,1466,568,1011,1640,1733,1890,1139,119,2860,2803,1570,2311,3261,2154,2048,1965,2980,3384,1654,1743,1484,20...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,0.4314806144175144,-0.36569595808664096,-0.0032099369180387514,-0.40195737736821424,0.8296849457389607,-0.32943691658390756,0.7573020385339275,-0.0032099369180387514,-1.1640277646940118,-0.039448282981301534,-0.3656959580...
3,642
Limb muscle weakness
35
89
2.420953
0.01548
Q9BTV4,Q9NR77,Q92734,Q99720,Q15067,Q96T60,Q13126,Q9Y5P6,Q96BR5,Q14739,Q9Y281,P00846,Q12824,Q13049,Q7LG56,Q7RTS9,Q99496,Q7Z406,Q8N0X7,P06753,Q3ZAQ7,P07196,Q15046,O75298,Q00796,Q14203,Q9BQT8,Q15120,P38935,P39210,Q15650,P02545,P37198,O14908,Q15813
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
667,267,262,9,398,544,18,817,540,31,297,162,534,43,429,46,854,317,194,682,843,73,696,448,326,329,624,840,454,212,238,726,606,482,743
2719,3241,482,3170,2964,1372,448,1282,1788,162,726,2372,682,73,1718,996,2217,3475,2846,1632,1001,1203,606,454,212,2928,1948,1549,1802,2536,891,1636,2032,2976,833,1730,1553,1466,1952,3100,2538,326,1813,3057,534,43,18,3633,1651,329,3295,1573,31,696,398,840,1483,238,743,2809,2161,843,3483,3063,1492,429,46,317,1973,3195,19...
-0.4744874152715812,-0.8735800140144077,0.7211076503875371,-0.8009947951684113,-0.6195767634991557,0.14172133947363577,0.7573020385339275,0.17794870135979338,-0.039448282981301534,1.44463503950887,0.50389952531643,-0.293180236639351,0.5401059130940894,2.2035770349778274,-0.0032099369180387514,0.3228367256941829,-0.2206...
3,642
Calcium ion binding
21
93
2.420175
0.015513
P80303,P55327,Q02818,Q66K14,Q9UM22,P61201,Q96AY3,Q9Y4G8,P19022,Q8NI22,P67936,Q9NWM8,O43852,Q14257,P0DP25,Q9Y680,Q9NZM3,Q9BUP0,P04083,Q13813,Q9BRK5
Functions
GO Molecular function
msigdb_gomf
11,255,15,163,35,302,54,198,312,61,185,71,78,80,85,101,106,377,236,370,132
1045,360,1114,445,78,1278,1936,3598,2207,1864,3133,2651,1441,3636,236,1716,2653,2917,1718,3134,85,3538,488,873,2658,417,527,1448,1625,312,2735,878,883,491,2221,1383,1056,1798,566,686,1800,888,2537,255,893,2039,302,185,11,15,3294,1013,2238,1071,370,2241,80,3614,2756,1020,163,3347,1661,2690,2409,2252,3517,2948,61,1027,75...
0.28661790671407417,0.8658734867848911,0.2503969717100796,0.7573020385339275,2.1313283265493896,0.17794870135979338,-0.11193170763769089,-2.182093097988025,-0.2206738976316064,-0.07568886835881676,-0.7647060824085025,-0.43822119087257283,0.10549180847782079,-4.627653579320756,1.1914848887169478,-0.0032099369180387514,-...
3,642
Cis trans isomerase activity
12
30
2.414604
0.015752
Q9Y680,Q00688,Q9NWM8,P26885,Q13427,Q13451,Q9Y3C6,Q6UX04,Q9Y237,Q96AY3,Q02790,P62942
Functions
GO Molecular function
msigdb_gomf
101,609,71,103,692,693,382,703,381,54,369,60
988,2648,2523,2530,103,2133,1631,2305,2974,60,609,369,836,1222,692,693,1072,2048,2160,1402,703,750,54,2257,1034,71,1694,381,382,101
0.3228367256941829,-0.43822119087257283,-0.36569595808664096,-0.36569595808664096,1.8784066596115039,-0.18442420720352415,0.03302618423136544,-0.2569259022510854,-0.6195767634991557,2.4202850586689473,0.6125126132127564,0.8658734867848911,0.4314806144175144,0.21417390765469435,0.5401059130940894,0.5401059130940894,0.28...
3,642
Neuron apoptotic process
9
49
2.411165
0.015902
O95831,Q07820,P09601,Q99720,P07196,P48507,Q96A26,Q9NR28,Q01105
Processes and pathways
GO Biological process
msigdb_gobp
64,187,166,9,73,177,155,157,213
3043,3416,1116,3213,1790,64,2968,2124,1868,1717,3573,1869,73,1376,166,1285,1942,564,2532,1876,1298,1635,177,224,2930,1802,3180,2034,1882,1731,2470,2978,213,187,838,2046,841,1900,3067,1980,155,3069,2956,3442,9,2893,157,771,556
-0.6921363540246968,-1.127712223754586,0.2503969717100796,-0.8372860991952851,-0.039448282981301534,2.348055342926024,-0.6195767634991557,-0.18442420720352415,-0.07568886835881676,-0.0032099369180387514,-1.8545831244298248,-0.07568886835881676,2.2035770349778274,0.14172133947363577,1.4084761139436706,0.1779487013597933...
3,642
Oxidative phosphorylation
14
37
2.409307
0.015983
O96000,P00846,O95182,P56556,O95167,O75964,O75380,P03886,O75787,O95139,O75947,O75438,P06576,P18859
Processes and pathways
WikiPathways
msigdb_wp
681,162,184,645,595,108,79,49,235,634,388,234,390,365
1186,2280,2010,2011,1375,993,79,234,1281,235,388,108,634,595,2450,184,2120,681,162,49,2729,390,365,1288,730,2458,1201,2611,3179,1953,2038,645,3267,1021,2402,1906,2519
0.21417390765469435,-0.2569259022510854,-0.14817681559539894,-0.14817681559539894,0.14172133947363577,0.3228367256941829,2.1313283265493896,1.1914848887169478,0.17794870135979338,1.1914848887169478,0.8296849457389607,1.8061284441617231,0.5763102717789569,0.6125126132127564,-0.32943691658390756,1.3361529184365946,-0.184...
3,642
Abnormality of the mitochondrion
18
102
2.403474
0.01624
Q9UMS0,Q5JPH6,P00846,O43676,Q4J6C6,P23786,P20674,P35637,Q96CU9,Q7LG56,Q9P0J1,O75380,Q70HW3,P03886,Q9GZY8,Q9Y2R0,Q7Z406,O43772
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
134,401,162,136,41,74,139,286,374,429,47,79,17,49,51,121,317,59
1186,2198,1110,2280,136,2011,59,1375,993,79,1281,2209,871,2120,681,3400,560,162,49,2729,2733,2215,1795,2657,1122,3606,3475,727,2022,1288,139,638,2922,74,1543,1201,3092,1632,286,3139,2137,2928,1950,1877,1549,494,3179,1301,495,1208,833,1133,1466,645,2236,3420,1738,696,1228,2402,3058,1902,427,41,401,3483,3110,17,1320,429,...
0.21417390765469435,-0.2206738976316064,0.2503969717100796,-0.2569259022510854,1.5892531387800641,-0.14817681559539894,2.4202850586689473,0.14172133947363577,0.3228367256941829,2.1313283265493896,0.17794870135979338,-0.2206738976316064,0.39526806690703153,-0.18442420720352415,0.5401059130940894,-1.0913994610234883,0.64...
3,642
Muscle structure development
21
105
2.396725
0.016542
Q9H7B4,P41440,Q14012,Q7Z4V5,Q9Y281,Q96PU8,Q96EB6,Q13049,P09493,P61201,Q7Z406,P62942,P19022,Q8NC56,O43707,Q53EL6,Q15650,Q9NYL9,O75446,P10644,P12814
Processes and pathways
GO Biological process
msigdb_gobp
4,6,397,145,297,435,292,43,174,302,317,60,312,469,445,226,238,116,484,487,488
1185,445,776,1784,1785,1374,931,2286,484,1865,2119,1714,3429,726,2124,2844,872,174,487,3606,1942,488,3596,1448,1625,1541,312,2026,1543,1292,883,1127,1383,1001,2532,2461,1876,1057,6,2743,941,1008,891,944,1206,2034,1555,893,302,60,1472,3018,1214,2149,2978,3257,2238,3223,691,43,3144,1651,397,2680,1573,740,1077,1483,2548,2...
0.21417390765469435,0.7573020385339275,0.4676910964650831,-0.039448282981301534,-0.039448282981301534,0.14172133947363577,0.3590534415201943,-0.2569259022510854,0.7211076503875371,-0.07568886835881676,-0.18442420720352415,-0.0032099369180387514,-1.1640277646940118,0.50389952531643,-0.18442420720352415,-0.54702716460932...
3,642
Abnormal peripheral nervous system physiology
15
55
2.396655
0.016545
O95831,Q71SY5,Q9NR77,Q92734,Q99720,P07196,Q7LG56,Q9GZY8,Q00796,P38935,O95721,O60313,Q7Z406,Q9Y619,P39210
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
64,164,267,262,9,73,429,51,326,454,363,90,317,299,212
3170,2964,1114,1783,90,1788,363,64,726,73,3513,2846,1450,788,790,454,212,1948,1726,2227,1802,1636,2032,1951,833,1466,3181,3221,326,3107,2679,3295,840,2481,3063,1492,164,429,317,2693,1911,262,1831,544,9,51,3392,2895,267,1993,3239,3039,983,2579,299
-0.8009947951684113,-0.6195767634991557,0.2503969717100796,-0.039448282981301534,1.986811502084436,-0.039448282981301534,0.8658734867848911,2.348055342926024,0.50389952531643,2.2035770349778274,-1.454654879347933,-0.5470271646093248,0.10549180847782079,0.4676910964650831,0.4676910964650831,0.7573020385339275,1.26382253...
3,642
Endopeptidase activity
13
70
2.396403
0.016557
Q13043,P28072,P49721,P51784,Q4J6C6,Q9NZ08,Q5JRX3,Q92643,Q16740,P20618,P22695,P49720,P28070
Functions
GO Molecular function
msigdb_gomf
188,34,5,167,41,75,331,248,279,50,275,123,62
3471,3564,2358,1438,1713,1865,2788,2653,1718,2659,2023,1625,50,275,1722,62,34,1200,3313,1454,1633,2303,3401,1878,3098,123,5,167,687,3585,1806,568,648,351,837,188,3188,2980,279,1229,41,331,1577,3317,701,803,577,1326,3455,2820,3067,248,1825,3033,849,2332,2333,1505,621,3442,2259,3072,3121,547,1514,75,3308,1702,1703,1428
-1.2729912830023138,-1.781840294008653,-0.293180236639351,0.10549180847782079,-0.0032099369180387514,-0.07568886835881676,-0.5107560674697893,-0.43822119087257283,-0.0032099369180387514,-0.43822119087257283,-0.14817681559539894,0.03302618423136544,2.7091423080596084,1.082964630935729,-0.0032099369180387514,2.3841709813...
3,642
Dna replication pre initiation
16
68
2.395439
0.0166
Q9NRF9,P28072,P49721,O00231,O75832,O00487,P60900,P20618,Q9UL46,Q99436,P16104,P28070,P49720,Q9NR33,Q9Y619,P33993
Processes and pathways
Reactome Pathways
msigdb_reactome
269,34,5,589,449,590,568,50,518,621,600,62,123,220,299,565
589,2839,2113,1707,590,1188,1712,2912,724,3472,449,2845,875,600,824,50,1627,882,1199,828,1628,1722,2925,1126,62,34,1200,1002,2607,565,3177,2224,1727,1007,2031,1131,123,5,644,1207,1805,2307,892,568,1011,1640,1733,1890,2148,2149,1139,2677,2803,1307,3491,1653,2312,3384,1654,1824,621,1165,220,269,2514,518,1523,299
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,-0.0032099369180387514,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.5833007240749342,0.50389952531643,-1.2729912830023138,0.7573020385339275,-0.5470271646093248,0.39526806690703153,0.6125126132127564,0.4314806144175144,2.7091423080596084,0....
3,642
Slowly progressive
13
58
2.379045
0.017358
Q9Y281,O95831,Q9NR77,P41440,Q92734,Q99720,P07196,Q13049,O43707,Q9BRK0,O75787,Q14203,O75190
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,64,267,6,262,9,73,43,445,83,235,329,361
1110,3599,3471,1430,2201,445,361,2207,235,1282,1788,64,726,2372,73,3475,2919,2378,565,2223,454,1948,6,1549,644,891,1636,2034,1553,2538,43,329,3295,1573,740,840,2809,843,1232,3483,2551,2063,1492,3148,2693,262,540,2956,9,83,667,3392,267,1995,3446,1929,297,1428
0.2503969717100796,-2.218500306818185,-1.2729912830023138,0.10549180847782079,-0.2206738976316064,0.7573020385339275,0.8658734867848911,-0.2206738976316064,1.1914848887169478,0.17794870135979338,-0.039448282981301534,2.348055342926024,0.50389952531643,-0.293180236639351,2.2035770349778274,-1.2729912830023138,-0.5833007...
3,642
Pten regulation
14
71
2.374894
0.017554
P28072,P49721,P31751,O00231,P60900,Q16576,P20618,Q9UL46,P14373,Q99436,O75832,P67870,P49720,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,5,564,589,568,613,50,518,450,621,449,393,123,62
589,2839,2113,590,1188,1712,1784,3336,449,3173,2017,1717,450,824,1719,50,1199,828,1628,1722,2379,1126,62,34,1200,2740,1001,564,2224,2743,1727,1007,123,5,1207,2307,568,1011,1640,1733,1890,393,1137,1139,1217,2803,2473,3144,2155,3384,1654,3189,2245,1901,613,956,2557,1330,1824,2496,849,621,1165,854,1990,2340,2350,518,2271,...
0.6125126132127564,-0.5470271646093248,-0.18442420720352415,0.6125126132127564,0.21417390765469435,-0.0032099369180387514,-0.039448282981301534,-0.9824776229443855,0.7573020385339275,-0.8009947951684113,-0.14817681559539894,-0.0032099369180387514,0.7573020385339275,0.4314806144175144,-0.0032099369180387514,2.7091423080...
3,642
Negative regulation of response to external stimulus
11
58
2.363705
0.018093
Q07021,O43657,Q96RK4,P30511,P80303,Q96G23,Q9UMX5,P11274,P55011,P19474,P28070
Processes and pathways
GO Biological process
msigdb_gobp
186,346,206,10,11,44,16,175,277,56,62
3043,2283,346,3044,3087,2651,561,3636,2452,2968,2598,175,599,2735,56,1199,62,2132,10,2606,2532,885,887,2746,277,3100,3052,501,11,2673,3383,186,2242,1816,1080,3316,1156,1582,3509,1158,1499,44,2418,1679,1337,206,855,1763,2185,1349,1519,411,2435,3165,16,1427,1702,2000
-0.6921363540246968,-0.2569259022510854,0.9020601005809601,-0.6921363540246968,-0.7284199416787922,-0.43822119087257283,0.6487129491004436,-4.627653579320756,-0.32943691658390756,-0.6195767634991557,-0.40195737736821424,1.3723154099889678,0.6125126132127564,-0.4744874152715812,2.4925085579988733,0.21417390765469435,2.3...
3,642
Cytokine production
25
112
2.352321
0.018657
Q9NUQ9,Q9NRA0,P41440,Q9UBC1,P30511,Q9HCL2,Q9UJZ1,Q96EB6,P09601,Q13049,P23396,P19474,Q9Y6M1,Q07021,P26583,P14373,P78536,Q8NCF5,Q02952,Q13283,Q53EL6,P04083,O75787,O75116,Q9Y639
Processes and pathways
GO Biological process
msigdb_gobp
270,268,6,411,10,30,295,292,166,43,176,56,342,186,324,450,351,354,459,460,226,236,235,233,272
1529,2281,1368,1709,2587,2446,724,559,233,3087,235,2119,1714,2018,2452,2968,236,1868,2598,3573,2731,1051,1376,2214,166,2845,997,2217,3363,599,450,787,1625,2846,56,1626,2128,176,2026,324,2132,10,3547,2973,2532,1128,3140,3178,1457,6,1949,888,2464,943,896,3106,351,501,2752,650,3560,459,3019,3548,186,3344,835,43,460,2311,1...
0.06926009468413799,-0.2569259022510854,0.14172133947363577,-0.0032099369180387514,-0.40195737736821424,-0.32943691658390756,0.50389952531643,0.6487129491004436,1.1914848887169478,-0.7284199416787922,1.1914848887169478,-0.18442420720352415,-0.0032099369180387514,-0.14817681559539894,-0.32943691658390756,-0.619576763499...
3,642
Negative regulation of response to stimulus
61
265
2.338334
0.01937
P18887,Q9BW85,Q9NUQ9,Q9H3K2,Q9UBC1,P30511,P80303,Q99471,Q9UMX5,Q13641,O95881,Q8IWB1,Q9Y4L1,P55011,P30086,O60826,Q96EB6,P09601,Q13049,Q96G23,Q7LG56,P30153,P48507,P11274,P23396,P19474,Q9UKV5,P62942,Q8N0X7,P19022,P28070,Q96HY6,Q13043,Q07820,Q07021,Q8NC56,P00813,Q96RK4,Q6DKJ4,P26583,P14373,O75832,P78536,O60313,Q96C57,Q1328...
Processes and pathways
GO Biological process
msigdb_gobp
489,668,270,670,411,10,11,545,16,655,635,23,556,277,26,160,292,166,43,44,429,419,177,175,176,56,587,60,194,312,62,472,188,187,186,469,561,206,615,324,450,449,351,90,216,460,630,614,346,349,226,599,519,236,118,606,501,666,117,661,359
2646,2719,2198,2281,359,3043,2283,819,346,1531,90,1784,1937,160,3044,2207,1281,3087,449,934,3213,2651,349,2592,1788,1790,635,2211,561,3636,2452,726,2290,2968,236,2124,2598,1717,2915,3089,2844,2374,2731,2020,166,997,3363,175,873,599,450,787,3576,1123,3175,937,2127,489,312,2735,56,1719,176,3539,1199,324,883,62,2132,26,41...
-0.43822119087257283,-0.4744874152715812,-0.2206738976316064,-0.2569259022510854,0.8658734867848911,-0.6921363540246968,-0.2569259022510854,0.4314806144175144,0.9020601005809601,0.06926009468413799,1.986811502084436,-0.039448282981301534,-0.11193170763769089,1.44463503950887,-0.6921363540246968,-0.2206738976316064,0.17...
3,642
Demyelinating peripheral neuropathy
6
20
2.336956
0.019441
Q9NR77,P00846,P41440,P07196,P03886,Q13217
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
267,162,6,73,49,303
2591,2122,162,49,2729,73,2456,2846,1450,2223,6,833,3100,303,429,710,2084,267,1427,1428
-0.40195737736821424,-0.18442420720352415,1.44463503950887,2.7091423080596084,-0.4744874152715812,2.2035770349778274,-0.32943691658390756,-0.5470271646093248,0.10549180847782079,-0.2206738976316064,6.744295549381935,0.4314806144175144,-0.7284199416787922,1.0106084847967511,0.7934944666326158,0.5401059130940894,-0.14817...
3,642
Ras protein signal transduction
10
78
2.331928
0.019704
Q15392,Q86VI3,Q07960,P41440,P84095,Q9Y6W5,P11274,P57105,O75116,Q9Y4G8
Processes and pathways
GO Biological process
msigdb_gobp
3,227,128,6,168,245,175,118,233,198
3448,3043,2521,233,2119,1788,1790,1717,2844,822,175,1123,1872,2663,1627,1543,1384,2135,606,2303,6,642,887,2609,1636,945,1551,118,1731,3102,2614,278,3106,3255,168,1013,128,3223,2152,1569,460,838,1961,1964,3227,2312,2618,952,3,399,1487,1154,2940,3298,1581,227,1821,1757,3117,511,1028,1916,2766,2333,2956,2637,3207,768,3165...
-1.2003461062830174,-0.6921363540246968,-0.36569595808664096,1.1914848887169478,-0.18442420720352415,-0.039448282981301534,-0.039448282981301534,-0.0032099369180387514,-0.5470271646093248,0.4314806144175144,1.3723154099889678,0.2503969717100796,-0.07568886835881676,-0.43822119087257283,0.03302618423136544,0.06926009468...
3,642
Respirasome
19
53
2.326024
0.020017
O43676,P20674,O95139,P21912,P14927,P22695,P56556,P03886,O96000,P00403,O95182,Q6DKK2,P15954,O75380,O14949,O14548,Q96CU9,O95167,O75438
Localization
GO Cellular component
msigdb_gocc
136,139,634,638,391,275,645,49,681,560,184,69,683,79,344,343,374,595,234
1186,2280,343,344,2010,136,2011,1375,993,79,234,1281,634,595,2450,184,2120,681,3400,560,49,2729,2213,936,1445,727,3136,391,683,1288,139,638,275,1201,1632,790,1299,3179,645,1740,1021,2402,69,1320,1906,374,1593,3445,1929,1043,1612,2961,2519
0.21417390765469435,-0.2569259022510854,0.9020601005809601,0.9020601005809601,-0.14817681559539894,1.5892531387800641,-0.14817681559539894,0.14172133947363577,0.3228367256941829,2.1313283265493896,1.1914848887169478,0.17794870135979338,0.5763102717789569,0.6125126132127564,-0.32943691658390756,1.3361529184365946,-0.184...
3,642