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BioDecision-4B v2: training data
The exact data BioDecision-4B v2 was trained and tested on: typed biomedical decisions (Choice, Yes/No, Score) in the Tev1 / Jev prompt format. The training pool (train) has 1,750,239 rows; one shuffled epoch processed 1,750,208 of them (the trainer drops the final incomplete batch of 31).
BioDecision family
| BioDecision v2 (this release) | BioDecision v1 (previous) | |
|---|---|---|
| Full model: merged weights, load and run | biodecision-v2-4b | biodecision-tev1-4b |
| LoRA adapter for Qwen/Qwen3.5-4B | biodecision-v2-4b-lora | BioDecision v1 LoRA adapter |
| Training data, test sets and overlap masks | biodecision-v2-data | BioDecision v1 training data + part 2 |
| Live demo | biodecision-demo |
What changed from BioDecision v1
- Training pool: 1,750,239 decisions, 766,914,222 tokens (BioDecision v1: 1,100,763 and 433,417,407).
- 22 new sources: VAERS, FDA MAUDE, OnSIDES, PHEE (drug and device safety); FDA recalls, FDA warning letters, drug-label sections (regulatory); CDISC COSMoS, MedConceptsQA (standards and coding); ClinicalTrials.gov, TrialPanorama, Chia (trial design); CIViC, ClinVar, Open Targets (genomics); PrimeKG; DDXPlus; BioNLI, BC5CDR; MedInfo; CMExam, CMB (Chinese exams). BioDecision v1's second-stage sources (CT Open training questions, MedHallu, rule-built grounding checks) are counted with v1.
- BioDecision v1's data re-screened: detected matches to benchmark group IDs, NCT identifiers and normalised complete evidence states were removed during construction; further detected overlaps are excluded through the evaluation masks. DDI and DrugProt were rebuilt with every candidate pair; TrialBench label priors were capped.
- Robustness variants across existing and newly added sources (prompt injection inside the source, number and unit flips, long documents, not-enough-information cases), with labels derived by deterministic rules.
Tasks
| Use case | BioDecision v1 decisions | BioDecision v2 decisions | share | sources |
|---|---|---|---|---|
| Medical exams (English) | 321,305 | 325,451 | 18.6% | headqa, medmcqa, medqa, sciq, ultramedical_medqa_evol, ultramedical_textbookqa |
| Evidence QA over papers | 282,050 | 290,954 | 16.6% | evidence_inference, medical_abstracts, pubmed_rct, pubmedqa_artificial, pubmedqa_labeled |
| Trial design and protocol screening | 0 | 132,217 | 7.6% | chia (new), ctgov_usdm (new), trialpanorama (new) |
| Trial outcome prediction | 139,817 | 114,375 | 6.5% | ct_open_train, trialbench_adverse_event, trialbench_mortality_rate, trialbench_patient_dropout, trialbench_trial_approval, trialbench_trial_duration, trialbench_trial_failure_reason |
| Patient drug reviews | 108,882 | 112,868 | 6.4% | drug_reviews_condition, drug_reviews_rating |
| Drug and device safety | 7,928 | 109,136 | 6.2% | ade_corpus, maude (new), onsides (new), phee (new), vaers (new) |
| Drug, protein and chemical relations | 26,278 | 99,487 | 5.7% | bc5cdr (new), ddi_corpus, drugprot |
| Genomics and precision oncology | 4,068 | 79,414 | 4.5% | civic (new), clinvar (new), gad, opentargets (new) |
| Judging answers against a source | 71,044 | 73,417 | 4.2% | grounding_synth, mcq_noul, medhallu_artificial |
| Patient–trial matching | 65,597 | 64,187 | 3.7% | trec_ct |
| Data standards and coding (CDISC, ICD, ATC) | 0 | 60,802 | 3.5% | cosmos (new), medconceptsqa (new) |
| Diagnosis from symptoms | 0 | 54,257 | 3.1% | ddxplus (new) |
| Regulatory and quality | 0 | 53,279 | 3.0% | fda_enforcement (new), fda_warning_letters (new), spl_sections (new) |
| Biomedical knowledge graph | 0 | 47,100 | 2.7% | primekg (new) |
| General decisions (Tev1 replay) | 36,867 | 43,133 | 2.5% | tev1_general |
| Medical exams (Chinese) | 0 | 37,353 | 2.1% | cmb (new), cmexam (new) |
| Claim checking and medical NLI | 23,247 | 36,978 | 2.1% | bionli (new), medical_question_pairs, mediqa_rqe, nli4ct, pubhealth, scifact |
| Medical information questions | 13,680 | 15,831 | 0.9% | medinfo_qtype (new), medquad |
| Total | 1,100,763 | 1,750,239 | 100% | 57 sources |
Splits
| Split | Decisions | Use |
|---|---|---|
| train | 1,750,239 | training (one epoch) |
| dev | 23,847 | model selection |
| calibration | 21,407 | temperature and confidence-gate fitting, after overlap screening |
| benchmark | 46,199 | processed rows from the official test/dev splits of the 28 original benchmarks |
| benchmark_new | 21,798 | held-out test rows of the 22 sources added in BioDecision v2 |
Overlap masks
masks/<split>.json records the rows flagged by the conservative union of two overlap-screening scans, with the reasons: group (shared non-empty group ID), input (same normalised question, evidence and options, in any order), nct (a shared NCT number), or neardup:<train id> (at least half of a sampled sketch of its distinctive 13-word phrases occurs in one training row); scan1 / scan2 record which scan flagged it. Unflagged rows may still share evidence with training. Reported results exclude flagged rows: 1,958 of 46,199 benchmark rows, 2,607 of 21,798 added-source rows, 2,666 calibration rows and 3,206 dev rows. The script is decontam.py.
Where labels come from
label_origin is recorded for 1,729,863 training rows; 20,376 second-stage rows from BioDecision v1 have no value, shown below as unset:
| label_origin | train rows | meaning |
|---|---|---|
| gold | 1,235,373 | the source's own label |
| derived | 182,927 | follows deterministically from a source label by a rule: e.g. the yes/no form of an MCQ, and the robustness variants (prompt injection, number and unit flips, long documents) |
| synthetic_llm | 132,929 | LLM-written exam questions and answers from UltraMedical (85,190 textbook + 47,739 MedQA-evol) |
| gold_heuristic | 109,065 | a source's heuristic or machine-extracted label: PubMedQA's artificial labels (74,447), DDXPlus's simulated differentials (33,114), OnSIDES's model-extracted adverse events (1,504) |
| rule | 49,235 | built by a rule with a known answer |
| unset | 20,376 | no value recorded (BioDecision v1 second-stage rows: 8,979 CT Open, 7,712 MedHallu with LLM-written candidate answers, 3,685 rule-built grounding checks); labels from the source or a rule |
| augmented | 20,334 | earlier augmentations: 17,606 exam 'none of the listed' variants, 1,559 DrugProt other-relation variants, 1,169 Evidence Inference evidence substitutions |
No Jev predictions were used as training labels. The pool does include upstream LLM-generated material: UltraMedical's questions and answers (written with GPT-4) and MedHallu's hallucinated answers.
Sources and licences
Research use only: several sources are non-commercial. commercial_ok is recorded where available; 20,376 training rows have no value, which does not establish commercial permission. Respect each source's licence; benchmark test sets belong to their authors.
| Source | Train decisions | Licence | New in BioDecision v2 |
|---|---|---|---|
| pubmed_rct | 195,000 | unknown | |
| medmcqa | 156,175 | Apache-2.0 | |
| ultramedical_textbookqa | 90,782 | MIT | |
| pubmedqa_artificial | 76,467 | MIT | |
| trec_ct | 64,187 | CC BY-SA 4.0 (qrels) | |
| mcq_noul | 62,020 | as parent MCQ | |
| trialpanorama | 61,373 | Apache-2.0 (TrialPanorama); ClinicalTrials.gov public domain; PubMed abstracts (publisher copyright) | yes |
| drug_reviews_rating | 57,875 | CC BY 4.0 | |
| drug_reviews_condition | 54,993 | CC BY 4.0 | |
| ddxplus | 54,257 | CC-BY-4.0 (DDXPlus, Mila / Dialogue Health Technologies) | yes |
| drugprot | 53,560 | CC BY 4.0 | |
| ctgov_usdm | 53,360 | ClinicalTrials.gov (public domain, U.S. NLM) | yes |
| ultramedical_medqa_evol | 51,072 | MIT | |
| primekg | 47,100 | CC0-1.0 (PrimeKG); upstream DrugCentral CC BY-SA 4.0; upstream HPO annotations (HPO licence, attribution); upstream DisGeNET CC BY-NC-SA 4.0 | yes |
| tev1_general | 43,133 | mixed (Together Tev1) | |
| medconceptsqa | 38,919 | Apache-2.0 (MedConceptsQA); ICD code sets are U.S. government works (public domain); ATC (c) WHOCC Oslo, no commercial copying or distribution | yes |
| vaers | 37,901 | Public domain (US Gov, CDC/FDA VAERS); via HF mirrors vaers-outcomes (Apache-2.0) and vaers-narrative-generation (CC0-1.0); MedDRA terms | yes |
| maude | 35,786 | CC0-1.0 (openFDA MAUDE, public domain) | yes |
| ddi_corpus | 35,202 | CC BY-NC 4.0 | |
| trialbench_trial_duration | 30,623 | unknown (TrialBench) | |
| fda_enforcement | 29,308 | CC0-1.0 (openFDA, public domain) | yes |
| opentargets | 28,383 | CC0-1.0 | yes |
| clinvar | 23,668 | ClinVar (NCBI): attribution requested; submitter-authored text may carry submitter rights; ClinVar (NCBI): US-government public domain facts; attribution requested | yes |
| civic | 22,214 | CC0-1.0 | yes |
| trialbench_trial_approval | 22,051 | unknown (TrialBench) | |
| cosmos | 21,883 | CDISC COSMoS (permission confirmed by CDISC) | yes |
| onsides | 19,248 | CC-BY-4.0 (OnSIDES v3.1.1; MedDRA term names) | yes |
| cmexam | 19,120 | Apache-2.0 (github.com/williamliujl/CMExam LICENSE) + README: academic/research use only | yes |
| spl_sections | 18,980 | CC0-1.0 (openFDA drug labels, public domain) | yes |
| cmb | 18,233 | Apache-2.0 (github.com/FreedomIntelligence/CMB LICENSE) | yes |
| chia | 17,484 | CC-BY-4.0 (Chia, Kury et al. 2020) | yes |
| trialbench_trial_failure_reason | 15,010 | unknown (TrialBench) | |
| medquad | 14,931 | CC BY 4.0 | |
| trialbench_patient_dropout | 14,799 | unknown (TrialBench) | |
| bionli | 12,844 | CC BY 4.0 (BioNLI README, github.com/StonyBrookNLP/BioNLI) | yes |
| sciq | 12,765 | CC BY-NC 3.0 | |
| trialbench_mortality_rate | 12,179 | unknown (TrialBench) | |
| evidence_inference | 11,243 | MIT | |
| trialbench_adverse_event | 10,734 | unknown (TrialBench) | |
| bc5cdr | 10,725 | Public domain (NCBI/NLM US Government Work notice in CDR_Data/README.txt) | yes |
| mediqa_rqe | 9,730 | unknown | |
| medqa | 9,571 | CC BY 4.0 | |
| ade_corpus | 9,073 | unknown | |
| ct_open_train | 8,979 | see CT Open (BioDecision v1 training data, part 2) | |
| medhallu_artificial | 7,712 | see MedHallu (BioDecision v1 training data, part 2) | |
| medical_abstracts | 7,160 | CC BY-SA 3.0 | |
| phee | 7,128 | MIT (PHEE, github.com/ZhaoyueSun/PHEE) | yes |
| pubhealth | 6,313 | MIT | |
| gad | 5,149 | CC BY 4.0 | |
| headqa | 5,086 | MIT | |
| fda_warning_letters | 4,991 | Public domain (FDA warning letters, fda.gov) via HF mirror tim-a-wood/fda-warning-letters (card: other); eCFR public domain | yes |
| medical_question_pairs | 3,822 | unknown | |
| grounding_synth | 3,685 | derived from licensed rows (BioDecision v1 training data, part 2) | |
| nli4ct | 2,469 | CC BY-SA 4.0 | |
| scifact | 1,800 | CC BY-NC 2.0 | |
| pubmedqa_labeled | 1,084 | MIT | |
| medinfo_qtype | 900 | CC-BY-4.0 (MedicationQA, Ben Abacha et al. 2019) | yes |
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