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True about hepatitis A viurs ?
Ans. is 'c' i.e., Common cause of hepatitis in children HAV is the most common cause of hepatitis in children. HAV does not cause chronic hepatitis or cirrhosis. HBV (no HAV) helps in HDV replication.
3
Causes cirrhosis
Helps HDV replication
Common cause of hepatitis in children
Causes chronic hepatitis
Microbiology
null
ae29e3d1-085f-4e58-935d-893261415feb
multi
The following tests may be useful in the assessment of a patient with sarcoidosis
Investigations in Sarcoidosis Lymphopenia is characteristic and liver function tests may be mildly deranged. Hypercalcaemia may be present (reflecting increased formation of calcitriol - 1,25-dihydroxyvitamin D - by alveolar macrophages), paicularly if the patient has been exposed to strong sunlight. Hypercalciuria may...
4
Chest X-ray
ACE
Serum calcium
All of the above
Medicine
Immune system
4cf53dd4-1047-472f-877b-cb9a62d360b9
multi
which of the following SSRI is hea safe
SSRI * IMPOANCE Most widely prescribed antidepressant * MECHANISM Specifically acts on serotonin transpoers and increases serotonin in synapse. DRUGS FLUOXETINE FLUVOXAMINE DAPOXETINE CITALOPRAM ESCITALOPRAM ESCITALOPRAM SERALINE PAROXETINE USE FLUOXETINE=============CHILDHOOD DEPRESSION FLUVOXAMINE===========OCD DAPOX...
1
escitalopram
clomipramine
fluoxetine
amitriptilline
Psychiatry
Pharmacotherapy in psychiatry
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Choose the appropriate lettered structure in this MRI scan showing a transaxial section through the head. Which structure may be obliterated by a pituitary tumor?
(c) The suprasellar cistern can be obliterated by a pituitary tumor.
3
A
B
C
D
Anatomy
Head & Neck
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Pedigree Chart -
Ans. is 'c' i.e., Used to see genetic transmission Pedigreeo Provide graphic depiction of a family structure medical history'.o Person providing information is formed as pro band,o Special symbol is used for each designation,o Three generation pedigree should be made.o Closer the relationship of proband to the person, ...
3
Used for growth monitoring.
To assess side effect during chemotherapy
Used to see genetic transmission.
To assess developmental delay in infant
Pediatrics
Genetics And Genetic Disorders
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True about cornea –a) Power is 43 Db) Majority of refraction occur at air – tear interfacec) With the rule astigmatism is present because vertical meridian more steep than horizontal meridiand) Spherical structuree) Refractive index 1.334
It has already been explained in this chapter that maximum refraction occurs from the anterior surface of the cornea (at the air-tear interface) because the difference between refractive index of two medium is maximum at this site. The air has a refractive index of 1.00 and cornea has refractive index 1.376, the differ...
3
ab
bc
abc
bcd
Ophthalmology
null
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multi
Following is/ are the clinical feature/ s of lepromatous leprosy -
Ans. is 'd' i.e., All the above Important clinical features oflepromatous leprosyo Diffuse erythema, tingling, nasal stuffiness or ep is tax is are earliest manifestations.o Nodules with predeliction for external ears,o Madarosis (loss of eye lashes and eye brow s),o Saddle nose (Collapse of nasal bridge) and perforati...
4
Leonine facies
Loss of libido and impotence
Saddle nose
All the above
Skin
C. Mycobacteria
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multi
Causes of macrocephaly includes?
Causes of Megalencephaly Lysosomal storage diseases: Gangliosidosis, MPS Carbohydrate disorder: Galactosemia Aminoacidurias: Maple Syrup urine disease, Glutaric aciduria type-1 Neurogenerative diseases: Alexander disease, Canavan disease, Metachromatic leukodystrophy Neurocutaneous diseases: Neurofibromatosis, Tuberous...
4
Galactosemia
Weaver syndrome
Soto's syndrome
All of the above
Anatomy
General anatomy
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multi
The maximum dose of isotretinoin should not exceed
Oral isotretinoin duration of treatment varies according to dose but post-therapy relapse is minimized by treatment courses that amount to the total of 120-150 mg/kg Ref Harrison 20th edition pg 1233
4
30-60mg/kg
60-90 mg/kg
90-120 mg/kg
120-150 mg/kg
Dental
All India exam
cb346e41-7afd-4e14-8a96-779b317a8a5b
single
Which of the following is feature of reticulocyte?
Reticulocytes are non-nucleated spherical cells bigger than normal RBCs and are polychromatic (having a blue color) d/t the presence of free ribosomes & RNA. They are identified with supravital staining. Best stain to identify them is new methylene blue.
2
Constitute 10% of the red cells
No nucleus
Smaller in the size than RBCs
Mature in lymph nodes
Pathology
Hematopoeisis: Basic concepts
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multi
Nanotechnology has found tremendous application in the diagnosis of cancers because of all of following advantages, except
Ans'd. Nanocrystals exhibit a narrow difference between their excitation and emission peak spectra
4
Nanocrystals exibit bright, photostable fluorescence
Nonocrystals have a narrow spectrum wavelength
Peak spectrum wavelength is tunable
Nanocrystals exhibit a narrow difference between their excitation and emission peak spectra
Pathology
null
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multi
Complications of sphenoid sinus surgery are all except:
(d) Orbital emphysema(Ref. Cummings, 6th ed., 778)Orbital complications will follow maxillary, ethmoid and frontal sinus surgeries due to close proximity.
4
CSF leak
Optic nerve injury
Lateral rectus palsy
Orbital emphysema
ENT
Nose and PNS
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multi
Erosive ahritis is seen in all, except
Ref Semantischolar.org
1
SLE
Gout
Osteoahritis
Old age
Medicine
Immune system
806d1d4d-a49d-470f-a731-babad4a4d583
multi
A 9 1/2 -year-old girl presents to your office with an approximately 1 1/4 -cm nodule in her neck, just to the left of the midline and below her cricoid cartilage. It is nontender and moves when she swallows. It has been enlarging over the last several months and was not seen by the pediatrician at her 9-year-old check...
While reactive lymphadenopathy is by far the most common cause of neck masses in children; a lymph node should not move with deglutition and is more likely to be tender. A branchial cleft syst should be more lateral and the thyroglossal duct cyst should be higher and in the midline (although they can sometimes present ...
2
Reactive viral lymphadenopathy
Papillary thyroid cancer
A brachial cleft cyst
A follicular adenoma of the thyroid
Surgery
Plastic & Reconstructive Surgery
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Site of transplantation in Islet cell transplant for Diabetes mellitus is
The islets are then purified from the dispersed tissue by density-gradient centrifugation and can be delivered into the recepient liver (the preferred site for transplantation) by injection into the poal vein Ref: Bailey and love 27th edition Pgno :1552
2
Skin
Injected into the poal vein
Liver
Pelvis
Anatomy
General anatomy
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A young pt presents with jaundice. Total bilirubin is 21, direct is 9.6, alkphosis 84 KA units. Diagnosis is:
Answer is D (Obstructive jaundice): Direct bilirubinemia (conjugated birirubin > 15% of total bilirubin) along with high serum alkaline phosphatase (6-7 times normal) suggests the diagnosis of obstructive jaundice. AffirghnfeAre Total bilirubin (mg/di) 0.3 to 1.0 21.0 Direct bilirubin is 45% of total bilirubin Conjugat...
4
Hemolytic jaundice
Viral hepatitis
Chronic active hepatitis
Obstructive jaundice
Medicine
null
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A 20 year old man presents with swelling of left lower limb and hydrocoele. All of the following may be the causative agent EXCEPT:
Ans. (d) Onchocerca volvulusRef: Diagnostic medical parasitology 3rd/275, Park 19th /221* Onchocerca volvulus results in river blindness and subcutaneous nodules.* "Lymphatic filariasis" covers infection with three closely related nematode worms - W.Bancrofti, B. Malayi and B. timoria.* All three infections are transmi...
4
Brugia malayi
Brugia timoria
Wuchereria bancrofti
Onchocerca volvulus
Microbiology
Mycology
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Very high intraocular pressure, veically oval mid-dilated pupil and shallow anterior chamber is seen in:
Ans. B: Acute primary angle closure glaucoma
2
Primary open angle glaucoma
Acute primary angle closure glaucoma
Malignant glaucoma
Pupillary block glaucoma
Ophthalmology
null
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multi
Which of the following vaccines can be used in pregnancy in normal circumstances?
Pregnancy is not a contraindication or precaution for Influenza trivalent vaccine. This vaccine is recommended for women who will be pregnant during influenza season. Influenza live attenuated vaccine is contra indicated. Must Know - Principle: Live-virus vaccines are contraindicated during pregnancy because of the pos...
3
MMR vaccine
Varicella vaccine
Influenza trivalent vaccine
Hepatitis A vaccine
Social & Preventive Medicine
null
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True statement about listeria:
Ans. is. 'b' i. e., Motile by peritrichous flagella
2
Gram negative bacillus
Motile by peritrichous flagella
Commonest cause of community acquired meningitis
Only one serovar is known
Microbiology
null
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Acute graft rejection occurs within?
Hyperacute rejection: type 2 HSR, happens over span of few minutes to hours. Eg: kidney transplant Acute rejection: Few weeks to months(< 6 months) Chronic rejection: After 6 months. Graft vs host disease (Runt Disease): Acute GVH: < 100 days Chronic GVH: > 100 days
3
Few minutes
Few hours
< 6 months
6-12 months
Pathology
FMGE 2019
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The protein that carries iron from the gut to the body tissues is called
null
4
Ferritin
Haemosiderin
Myoglobin
Transferrin
Pathology
null
c8ae46e5-eb0a-4864-bc20-5179d0891e92
multi
After an endoscopy a technician kept the instrument for sterilization. Which of the following agent is used for sterilization of fibre optic instruments?
Glutaraldehyde, which has two reactive aldehyde groups, is 10 times more effective than formaldehyde and is less toxic. It denatures proteins and nucleic acids. Both proteins and nucleic acids contain essential -NH2 and -OH groups, which are the main sites of alkylation. In hospitals, it is used to sterilize respirator...
1
Glutaraldehyde
Chlorine
Autoclave
Phenol
Microbiology
null
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Cytokinee are secreted in sepsis in and systemic inflammatory response syndrome (SIRS) by:
ref Harrison 18/e p2223_2225 , Robbins 7/e p202 Cytokines are the peptide mediators or intercellular messangers which regulate immunological, inflammation,reparative host response.they are produced by widely distributed cells like macrophages ,monocytes, lymphocytes, platelets,fibroblast, endothelium,stromal cells etc....
1
Neutrophils
Adrenal
Platelets
Collecting duct
Anatomy
General anatomy
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Necrotizing lymphadenitis is seen in:
Kikuchi Fujimoto disease Or histiocytic necrotizing lymphadenitis It is Benign and self-limited disorder in young individuals characterized by regional cervical lymphadenopathy with tenderness Accompanied with mild fever and night sweats Diagnosed on the basis of an excisional biopsy of affected lymph nodes which shows...
2
Kimura disease
Kikuchi Fujimoto disease
Hodgkin disease
Castelman disease
Pathology
Auto Immune Disorders Introduction
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Enucleation of the eyeball is contraindicated in
Endophthalmities is treated by intravitreal injection of antibiotics. If not managed and removal of eye of eye is indicated.we should go for evisceration. This is because the outer coats of the eyeball are not involved and hence we should not remove it. Also it is more convenient to put aificial eye then orbital implan...
1
Endophthalmities
Panophthalmities
Intraoccular tumours
Painful blind eye
Ophthalmology
Diseases of orbit, Lids and lacrimal apparatus
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Colostrums has in compared to normal milk -
Colostrum contains a high concentration of proteins as compared to normal milk.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-491
3
Decreased K
Decreased Na
Increased proteins
Increased calories
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
3ee93576-d484-4bff-9171-c3375cd5428a
single
The prognosis of rhabdomyosarcoma is likely to be poor if the site of the tumor is ?
Ans. is 'c' i.e. Extremity Rhabdomyosarcomas of the extremities have alveolar histology which is associated with aggressive tumor biology. Also know RMS is the most common malignant tumor of the soft tissues in infants and children. MC site is head & neck region Among head & neck, orbit is the most common site.
3
Orbit
Paratesticular
Extremity
Urinary bladder
Surgery
null
cef4da9b-e2e4-4f6e-a3f2-7f3b75916ee3
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Pipkin classification is used for
COMMON FRACTURES CLASSIFICATION FRACTURECLASSIFICATIONOpen fracturesGustilo & Anderson Supracondylar Humerus Galand ( based on displacement )Proximal Humerus Neer ( 4 pa fractures )Distal Radius Frykman , FermandezPelvis Young & Burgess, TileFemoral head Pipkin's classificationFemoral neck ( Pediatric )Delbet classific...
3
Acetabular fractures
Pelvis ring fracture
Femoral head fracture
Femoral shaft fracture
Orthopaedics
All India exam
13d1a16b-7679-4da4-9ee1-c2cc3a7ce60b
single
Osteoarthritis does not affect:
Ans: d (Metacarpophalangeal joint)Ref: Maheshwari Ortho, 3rd ed, p. 252 & Harrison, 15thed, p. 1990
4
Knee joint
Hip joint
Interphalangial joint
Metacarpophalangial joint
Orthopaedics
Arthritis
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single
Most common viral cause of acquired aqueductal stenosis is ?
Out of the given options, only mumps and toxoplasma cause aqueductal stenosis. Toxoplasma is not a virus. Hence, the answer is mumps.
2
Rubella
Mumps
Toxoplasma
Enterovirus
Pediatrics
null
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Pulsatile GnRH is used for managing:
Ans. is d, i.e. Anovulatory infertilityPulsatile GnRH is used for:* Ovulation induction (in managing anovulatory infertility)* Delayed, puberty
4
Precocious puberty
Fibroid
DUB
Anovulatory infertility
Gynaecology & Obstetrics
Physiology & Histology
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The regional aerial resistance of the mesentery and kidney vessels is reduced by
In hyperdynamic sepsis, the peripheral aeriolar tone and BP are low but the cardiac output is often high; therefore the vasoconstrictor noradrenaline (norepinephrine) is appropriate to restore BP, usually at the price of some reduction in cardiac output.In most cases, a vasoconstrictor such as noradrenaline (norepineph...
3
Dopamine
Dobutamine
Nor adrenaline
Isoprenaline
Medicine
C.V.S
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All true about pisiform, except Manipal 11
Ans. Can be seen on newborn X-ray
3
Last carpal bone to ossify
Attached to flexor carpi ulnaris
Can be seen on newborn X-ray
It is a sesamoid bone
Forensic Medicine
null
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Which of the following is an indication for using mifepristone?
Mifepristone, also known as RU486, is an antiprogestin that has been used for treatment of leiomyomas. Mifepristone diminishes leiomyoma volume by approximately half and it is effective in improving symptoms. Other uses of mifepristone: For termination of early pregnancy For emergency postcoital contraception Endometri...
2
Ectopic pregnancy
Fibroid uterus
Molar pregnancy
Habitual aboion
Gynaecology & Obstetrics
null
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After passing his physical exam, a 19 year old army recruit gives urine and blood samples for fuher testing. Serum analysis yields elevated ALT, HBsAg, Anti-HBc, HBeAg, and bilirubin. All other values are normal. Which of the following is the hepatitis B status of this recruit?
The presence of elevated ALT, HBsAg, anti-HBc, HBeAg, and bilirubin all point to active hepatitis B. An asymptomatic carrier does not have elevated ALT and bilirubin. The absence of findings on physical examination rules out fulminant hepatitis B. Recovery from acute self-limited HBV is associated with the presence of ...
2
Asymptomatic carrier
Chronic active carrier
Fulminant hepatitis B
Recovered from acute self-limited HBV
Microbiology
null
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Which of the following organs does not show pale infarct?
Pale infarcts are typically seen in hea, kidney and spleen. Red infarcts principally occur in organs with dual blood supply such as lungs, or in those organs with extensive collateral circulation such as brain and small intestine. In both types of infarcts, infarcted area shows coagulative necrosis, but in red infarct ...
1
Lung
Hea
Kidney
Spleen
Pathology
null
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Mitochondrial chromosomal abnormality leads to
Ref Robbins 8/e p171;9/e p172 Example of mitochondrial inheritance is leber's hereditary optic neuropathy.leigh's disease ,MELAS - Mitochondrial encephalopathy Lactic acid Stroke like syndrome Neuropathy , ataxia, retinitis, Kearns Sayre syndromes, chronic progressive external opthalmoplegia,Pearson syndrome M
1
Leber's hereditary optic neuropathy
Angelman syndrome
Prader villi syndrome
Myotonic dystrophy
Anatomy
General anatomy
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Gestational sac is seen by TVS at-
Ans. is 'a' i.e., 5 weeks [Ref: Dutta's Obs 7th/ep. 68}TVS showso Gestational sac & yolk sac - 5th weeko Fetal pole & cardiac activity - 6th weeko Embryonic movements - 7th weeko Fetal gestational age is best determined by CRL between 7th to 12th weeks (variation +/- 5 days)o Doppler effect of ultrasound can pick up he...
1
5 weeks
6 weeks
7 weeks
8 weeks
Gynaecology & Obstetrics
Diagnosis of Pregnancy
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Mechanism of action of transexaminic acid is?
Ans. is 'd' i.e., Prevents fibrinolysis o Tranexamic acid binds to the lysine binding sites on plasminogen and prevents its combination with fibrin and thus prevents fibrinolysis.
4
Decrease vascular permeability
Smooth muscle contraction
Activates Plasmin formation
Prevents fibrinolysis
Pharmacology
null
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Rotator interval is between:
(c) Supraspinatus and subscapularis- Rotator interval is a triangular portion of shoulder capsule which lies between supraspinatus and subscapularis tendon and coracohumeral ligament passes through it.
3
Supraspinatus and teres minor
Teres major and teres minor
Supraspinatus and subscapularis
Subscapularis and infraspinatus
Orthopaedics
Injuries Around Shoulder
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Which of the following drug is used as a Transcranial patch for Parkinson's disease
Rotigotine is a non-ergot dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS). It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours. However, it was withdrawn in 2008 because of crystal ...
2
Levodopa
Rotigotine
Selegiline
Carbidopa
Pharmacology
null
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The treatment of Acute Manic Episodes is
Lithium
2
ECT
ECT
Diazepam
Sodium valproate
Psychiatry
null
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In cochlear implants electrodes are most commonly placed at -
null
2
Oval window
Round window
Horizontal semicircular canal
Cochlea
ENT
null
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Hypersensitivity vasculitis is most commonly seen in:
. Post capillary venules
1
Post capillary venules
Aerioles
Veins
Capillaries
Pathology
null
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Hill Sach&;s lesion is most commonly seen in
HILL-SACH&;S lesion is most commonly seen in recurent shoulder dislocation. It is a posterolateral defect in the head of the humerus.This is produced due to the impact of posterolateral pa of the head of the humerus against the sharp anteraior margion of the glenoid rim. ref:textbook of ohopedics ,john ebnezar,4th edit...
1
Recurrent shoulder dislocation
Posterior shoulder dislocation
Fracture neck of humerus
Anterior shoulder dislocation
Orthopaedics
Shoulder and arm injuries
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Natural killer cell is -
Ans. is 'c' i.e., Null cells Null cells (Large granular lymphocytes or LGLIo Null cells are called so because they lack features of surface markers of both B and T lymphocytes. The account for 5 to 10% of peripheral blood lymphocytes.o They are also called "large granular lymphocytes (LGL)"as they contain large azuroph...
3
MHC restricted
Antibody dependent
Null cells
B-lymphocytes
Microbiology
Immunology
455bd18a-8840-415f-b6ba-cdf2dc55df5d
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Radionucleide of choice for the assessment of renal function?
Ans: b (DTPA) Ref: Bailey, 24th ed, p. 129999Tc DTPA (diethyl triamino penta acetic acid)Useful to assess the functional status of kidney.DTPA behaves like inulin: completely filtered by the glomeruli, and not absorbed by the tubules. On using a gamma camera the dynamic action of kidney can be assessed.Other substances...
2
MIBG
DTPA
Thallium
Sulphur
Radiology
Genito Urinary System
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Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone?
Ans. A. Mefloquine. (Ref. H-17th/pg 1292; Table 203-6)Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone is Mefloquine.Regimens for the Rx of MalariaType of Disease or RxRegimen(s)Uncomplicated Malaria Known chloroquine- sensitive strains of Plas...
1
Mefloquine
Doxycycline
Ataquinone/Proguanil
Primaquine
Medicine
Infection
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Most common nerve injured in ligation of superior thyroid aery:
The external laryngeal nerve lies in relation to superior thyroid aery. The recurrent laryngeal nerve lies close to inferior thyroid aery.
4
Recurrent laryngeal nerve
Facial nerve
Mandibular nerve
External laryngeal nerve
ENT
null
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Antiphospholipid syndrome ( APS) is associated with all of the following except:
Indications for APLA testing 3 or more consecutive first trimester losses Unexplained IUGR Early onset severe preeclampsia Unexplained thrombosis Autoimmune connective tissue diseases like SLE False positive serological test for syphilis (refer pgno:333 sheila 2nd edition)
1
pancytopenia
Recurrent aboions
Venous thrombosis
pulmonary hypeension
Gynaecology & Obstetrics
General obstetrics
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Duret hemorrhage seen in -
Ans. is 'a' i.e., Brain o Duret - Bernard hemorrhage can be seen with severe compression of the midbrain and other brainstem areas during transtentorial herniation.
1
Brain
Kidney
Heart
Lung
Medicine
C.N.S.
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Which of the following is/are features of dishpan digit?
Dishpan digit Finger of the child who indulges in sucking habit. On examination, it will provide valuable information about the habits. They are: Reddened. Exceptionally clean thumb / nail / finger. Fibrous rough callus.
4
Reddened finger
Exceptionally clean thumb
Fibrous rough callus
All of the above
Dental
null
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Age limit for HDI?
According to previous editions of Park (21st/e) the minimum and maximum established values for life expectancy atbirth was 25 years and 85 years, respectively.   However, Now the minimum established value is 20 years and maximum value is the highest observed value during time series, i.e. the country which has the high...
1
25 to 85 yrs
25 to 50 yrs
15 to 45 yrs
50 to 75 yrs
Unknown
null
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35-year-old woman presents to OPD with complains of headache after hitting her head accidentally with the wall while doing household chores . An MRI was ordered which confirmed presence of blood clot in the great cerebral vein of Galen. Obstructed vein is a direct tributary of which of the following venous structures?
Veins of the brain are direct tributaries of dural venous sinuses. Emissary veins connect dural venous sinuses with the veins of scalp; Pterygoid venous plexus communicates with cavernous sinus through an emissary vein; Diploic veins lie in channels in the diploe of skull and communicate with dural sinuses, veins of sc...
4
Emissary veins
Pterygoid venous plexus
Diploic veins
Dural venous sinuses
Anatomy
Brainstem lesions and blood supply of CNS
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multi
Cystocoele is prolapse of
Cystocoele is prolapse of the anterior 2/3rd vaginal wall while prolapse of lower 1/3rd of the anterior vaginal wall is called as urethrocele. The anterior wall prolapse or cystocele is the most common form of female pelvic organ prolapse Rectocele is prolapse of lower 2/3rd of the posterior vaginal wall Enterocoele is...
1
Upper 2/3rd of anterior vaginal wall
Lower 2/3rd of anterior vaginal wall
Upper 1/3 of anterior vaginal wall
Lower 1/3 of anterior vaginal wall
Microbiology
All India exam
21e8bc04-fb23-45b1-b232-38e3a05943fd
multi
All of the following drugs cause discolouration of urine EXCEPT :
null
2
Nitrofurantoin
Digoxin
Azo dyes
Rifampicin
Pharmacology
null
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multi
All are true about bulbar urethral rupture, except:
Ans. (b) Floating prostate on per rectal examination* Floating prostate is seen in membranous urethral injury* Perineal hematoma seen in Bulbar urethral injury.* Deep Perineal pouch hematoma is seen in Membranous urethral injury.
2
Perineal hematoma
Floating prostate on per rectal examination
Collection of urine in perineum
Bleeding per urethra
Surgery
Urethra & Penis
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multi
Which of the following is mechanism of action of dapsone?
Dapsone is analogue of PABA Competively inhibits dihyropteroate synthase - decreases folic acid synthesis. It can cause mild hemolysis, anemia and psychosis. Uses: Leprosy Malaria Prophylaxis of pneumocystitis Dermatitis herpetiformis
4
Inhibit the cell wall synthesis
Inhibit the sterol of cell wall
Inhibit the protein synthesis
Compete with PABA in folic acid synthesis
Pharmacology
Mycobacterial Diseases (TB, Leprosy and MAC)
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multi
In a 4-year old boy who has history of pyogenic infections by bacteria with polysaccharide-rich capsules, which of the following investigations should he done?
Ans. d. IgA and IgG2 deficiency Recurrent episodes of pyogenic infections by capsulated organisms are most commonly observed in patients with selective IgA deficiency and decreased IgA or IgG subclass levels (especially IgG2). "Specific Antibody Deficiency (SAD) patients generally present with recurrent upper and/or lo...
4
IgA deficiency
IgG 1 deficiency
IgG2 deficiency
IgA and IgG2 deficiency
Microbiology
null
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single
Hurthle cell tumour is:
HURTHLE CELL CARCINOMA: Hurthle cell carcinomas account for approximately 3% of all thyroid malignancies. Considered to be a subtype of follicular thyroid cancer.
2
Papillary carcinoma thyroid
Follicular carcinoma thyroid
Medullary carcinoma
None of the above
Surgery
null
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multi
Rhinophyma is associated with-
Rhinophyma is a slow-growing benign tumor due to hypertrophy of sebaceous gland.
1
Hypertrophy of the sebaceous glands
Hypertrophy of sweat glands
Hyperplasia of endothelial cells
Hyperplasia of epithelial cells
ENT
null
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single
Amphotericin B toxicity can be reduced by?
New amphotericin B formulations: In an attempt to improve tolerability of i.v. infusion of AMB, reduce its toxicity and achieve targeted delivery, 3 new lipid formulations of AMB have been produced. (a) Amphotericin B lipid complex (ABLC): Contains 35% AMB incorporated in ribbon like paicles of dimyristoyl phospholipid...
1
Incorporating it in liposomal complex
Combining with fluconazole
Combining with flucytosine
Injecting the drug with dextrose
Pharmacology
Chemotherapy
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single
Which of the following sonographic finding confirms intra uterine pregnancy
Normal gestational sac implants eccentrically in the endometrium. Anechoic center surrounded by single echogenic rim = intra-decidual sign. Two concentric rings echogenic surrounding sac = Double decidual sign.
4
An echogenic rim along one side of decidua.
Two concentric echogenic rings surrounding the sac.
A sac positioned eccentrically within endometrium.
All of the above.
Gynaecology & Obstetrics
null
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multi
Founder members of vision 2020 are A/E
B i.e. UNICEF
2
WHO
UNICEF
ORBIS
International Agency for prevention of blindness
Ophthalmology
null
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single
Which of the following is the auto antibody associated with Rheumatoid arthritis -
Anti CCP
2
Anti DLE
Anti CCP
Antids DNA
Antihistone
Unknown
null
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single
In preterm labour which drug has Neuro-protective role?
Ans. (a) MgSO4 Ref: Williams Obstetrics 25th Ed; Page No-730* To prevent convulsions; Administer IV MgSO4 and Continue IV MgSO4 for 24 hours after delivery.* Always avoid Nifedipine and b-blockers, because they cause severe maternal complication.Antihypertensive Drug Therapy Issues* Discontinue medications: This may be...
1
MgSO4
Nifedipine
Ritoridine
Isoxsuprine
Gynaecology & Obstetrics
Pharmacotherapeutic in Obstetrics
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single
Dosage of Vitamin–A for children between 1–3 years –
null
2
1250 IU
1333 IU
1667 IU
2333 IU
Pediatrics
null
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single
Accommodation is brought about by:
Ans: d (Ciliary body contraction) Ref:Ganong, 22th ed, p. 154Accommodation is brought about by ciliary muscle contractionAccommodationThe process by which the curvature of the lens is increased is called accommodation.Mechanism: At rest the lens is under tension by lens ligaments & lens is pulled into a flattened state...
4
Dilation of iris
Dilation of pupil
Lens zonules made tense
Ciliary body contraction
Ophthalmology
Elementary Optics
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single
A patient with suspected subarachnoid haemorrhage presents with blood isolated in the fouh ventricle on a CT scan. Aneurysmal rupture is likely to have resulted from
*Saccular aneurysm at size of >7mm and at top of basilar aery and at origin of posterior communicating aery are at greater risk of rupture . Ref Harrison20th edition pg 2445
3
Posterior Inferior Cerebellar Aery Aneurysm
Anterior Communicating Aery Aneurysm
Posterior Communicating Aery Aneurysm
Basilar Aery Tip Aneurysm
Medicine
C.N.S
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The term 'disease control' employs all of the following except-
Ans. is 'd' i.e., Reducing the prevalence of the disease o The term disease control describes, reducing the i) The incidence of disease ii) The duration of disease and consequently the risk of transmission iii) The effects of infection, including its complications iv) Financial burden to the community
4
Reducing the complications
Reducing the risk of fuher transmission
Reducing the incidence of disease
Reducing the prevalence of the disease
Social & Preventive Medicine
null
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multi
In haemoptysis blood usually comes from
null
3
Bronchial veins
Pulmonary veins
Bronchial arteries
Pulmonary arteries
Medicine
null
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multi
Internationally quarantinable disease are -
Ans. is 'd' i.e., All of the above Quarantinable diseases o Diphtheria o Yellow fever o Infectious TB o SARS o Plague o Small pox o Viral hemorrhagic fever Also Know : Quarantine was first applied for plague. Quarantine period for yellow fever is 6 days. Quarantine has been 'replaced by active surveillance'.
4
Plague
Cholera
Yellow fever
All of the above
Social & Preventive Medicine
null
eea5b2b7-6b90-4ee5-9f4b-35c6ea77ec6b
multi
Projections from substantia nigra pars compacta to striatum releases
null
2
GABA
Dopamine
Glutamate
Aspartate
Physiology
null
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single
Sublingual nitroglycerin for treatment of acutechest pain can cause ?
Ans. is 'b' i.e., Headache Due to vasodilatation there may be tachycardia, palpitation, flushing, headache, dizziness and fainting may occur. Adverse effects Due to vasodilatation tachycardia, palpitation, flushing, headache, dizziness and fainting may occur. Rashes are common paicularly with pentaerythritol tetranitra...
2
Hypeension
Headache
Bradycardia
Sexual dysfunction
Pharmacology
null
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single
Denominator in dependency ratio ?
Ans. is 'b' i.e., Age group 15-65 years Dependency ratio The propoion of persons above 65 years of age and children below 15 years of age are considered to be dependent on the economically productive age group (15-64 years). The ratio of combined age group 0-14 years plus 65 years and above to the 15-65 years age group...
2
Age group < 15 years
Age group 15-65 years
Age group > 65 years
< 15 years and > 65 yeas
Social & Preventive Medicine
null
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single
Metal ceramic restorations fail usually due to fracture of the cervical material. This can be avoided if:
null
2
Occlusal forces are minimal
Casting is so designed as to reduce stress on ceramic material
Metal is not more than 0.5 mm thick
Ceramic is at least 1.5 mm thick
Dental
null
b4d58c84-55e0-437a-ad51-d5de19dc2fc6
multi
Skin lesion in meningococcal meningitidis is due to-
null
2
Exotoxin
Endotoxin
Allergic reaction
Direct vascular Damage
Microbiology
null
f1f9342d-8187-48a0-8d52-5e6ab7fa87f2
multi
Hand and foot syndrome is an adverse effect of:
Capecitabine and 5-FU can cause hand and foot syndrome. Diarrhea is the most common adverse effect of 5-FU. 5-FU can also cause bone marrow suppression. Drugs commonly implicated are: Capecitabine 5-Fluorouracil Cytarabine Pemetrexed Doxorubicin
1
5-Fluorouracil
Bleomycin
Etoposide
Actinomycin D
Pharmacology
Cytotoxic Anticancer Drugs
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single
Which of the following skin conditions is treated with PUVA therapy?
PUVA is used to treat extensive psoriasis and psoriasis that has not responded to other therapies. PUVA stands for psoralens plus UVA. Psoralens are used orally followed by exposure of lesions to measured amount of a type of ultraviolet light-UVA. Sho term side effects of PUVA therapy include tanning, pruritus, nausea,...
1
Psoriasis
Tinea versicolor
Lichen planus
Porphyria cutanea tarda
Skin
null
5bd7c211-d519-4173-a982-1b501e1943a6
single
Products of complete hydrolysis of cardiolipin are:
3 glycerol, 4 fatty acids , 2 phosphates Cardiolipin is a complex phospholipid, which can be antigenic. The structure is glycerol attached to two phosphatidic acids. Each phosphatidic acid contains one glycerol, 2 FA and one phosphate. So in total 3 glycerol, 4 fatty acids, 2 phosphates are present in cardiolipin.
1
3 glycerol, 4 fatty acids , 2 phosphates
3 glycerol, 4 fatty acids , 1 phosphates
3 glycerol, 3 fatty acids , 2 phosphates
5 glycerol, 4 fatty acids , 2 phosphates
Biochemistry
Chemistry of Lipids
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single
All of the following are used for monitoring air pollution except
Indicator for air pollution Remarks Sulphur dioxide Best Smoke and soiling index Air filtered through white paper and stained is measured under photoelectric meter Grit and dust measurement Deposit gauzes collect grit dust and others solid Coefficient of haze Amount of smoke and other aerosol in the air Air pollution i...
4
SO2
Soiling index
Coefficient of haze
E. coli
Social & Preventive Medicine
Environment
101ffce9-309d-44b3-9728-cc577aa81302
multi
A newborn with respiratory distress was noted to have marked nasal flaring, audible grunting, minimal intercostal chest retarction. The respiratory rate was 30/min. The Silverman score of this child would be? NOT RELATED- MEDICINE
.
4
1
2
3
6
Pharmacology
All India exam
1201e6c5-5070-45c8-b141-3c3f0c2754d1
single
The symptoms of Hyperparathyroidism include ?
Ans. is 'd' i.e., All of the above
4
Constipation & muscle weakness
Anorexia & weight loss
Polydipsia & polyuria
All of the above
Surgery
null
f7a5befc-c9d7-47bf-a625-52b623c87c25
multi
Main pancreatic duct is derived from ?
The pancreas develops from the two endodermal buds, dorsal and ventral, that arise from the pa of the gut that later forms the second pa of the duodenum. The ventral bud forms the lower pa of the head, and the uncinate process of the pancreas, while the upper pa of the head, the body and the tail are formed from the do...
1
Paly from the dorsal pancreatic bud and paly from the ventral pancreatic bud
Dorsal pancreatic bud only
Ventral pancreatic bud only
None of the above
Anatomy
null
1166931d-79a9-4d69-96b7-83c4aa9c0208
multi
Ahritis mutilans is seen in:
Psoriatic Ahropathy
4
OA
Rheumatoid ahritis
Reiters syndrome
Psoriatic Ahropathy
Surgery
null
e82ebf61-292c-4d7f-a01e-8e39008842a7
single
Which of the following is TRUE about cholera toxin?
V cholerae produce a heat-labile enterotoxin. Ganglioside GM1 serves as the mucosal receptor for subunit B, which promotes entry of subunit A into the cell. Cholera toxin catalyzes the ADP ribosylation of the G protein, rendering it unable to dissociate from the active adenylate cyclase complex. This causes persistent ...
3
Increases the levels of intracellular cyclic GMP
Acts through the receptor the opiates
Causes continued activation of adenylate cyclase
Inhibits the enzyme phosphodiesterase
Microbiology
null
65be5346-6230-4900-be9d-1a598c785997
multi
Glucose transporters present in the Beta cells of the Islets of Langerhans is:
Ans. B. GLUT2GLUTTissue LocationFunctionGLUT 1Brain, Placenta, Kidney, RBCBasal Glucose UptakeGLUT 2Liver, Pancreas, IntestinePancreas-Insulin SecretionGLUT 3Brain (Neurons), PlacentaBasal Glucose UptakeGLUT 4Skeletal Muscle, Adipose Tissue, Cardiac MuscleInsulin stimulated uptake after mealsGLUT 5Small Intestine, Test...
2
GLUT1
GLUT2
GLUT3
GLUT4
Biochemistry
Carbohydrates
b3c251fc-d600-49f0-b005-db8fc46c14cc
single
Muscular timidity caused by opioids is due to the agonist effect on which receptor
Refer Miller 7/ep781 Truncal rigidity caused by highly lipid soluble opioids like Fentanyl is supraspinal in origin. It is mainly caused by stimulation of mu receptors whereas kappa and delta receptors tend to reduce the rigidity
1
Mu
Kappa
Delta
Sigma
Pharmacology
Anesthesia
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single
Maximum radiopaque shadow in ovary is seen in
Teratoma is most radio-opaque because of its calcifications (Ref: Radiology Review Manual by Wolfgang Dahne 6thEtd, 1010)
1
Teratoma
Dysgerminoma
Mucinous cyst adenoma
Granulose cell tumour
Radiology
All India exam
9e14a61e-9991-453a-a7fb-5b0d7251cea0
single
Indication for induction of labour is :
PIH at term
2
Placenta pre
PIH at term
Hea disease at term
Breech
Gynaecology & Obstetrics
null
397a34a4-f6ea-4958-bf79-933cddc691c7
single
Antibiotic of choice for lymphedema is ?
<p> Lymphoedema Accumulation of fluid in extracellular and extravascular fluid compament , commonly in subcutaneous tissue. Classification: 1. Primary - without any identifiable disease. 2. Secondary- acquired due to definitive cause. Primary lymphoedema:- Affects commonly females. Common in lower limb and left side. I...
1
Penicillin
Amikacin
Metronidazole
Ceftazidime
Surgery
Vascular surgery
266c3949-61fc-4dfd-98d4-dec06bc18bcd
single
What is the content of ethinyl estradiol in very low
null
3
30µg
25µg
20µg
15µg
Social & Preventive Medicine
null
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single
The first step in fatty acid synthesis involves:
Ans. A. Acetyl-CoA carboxylase(Ref Harper 31/e page 217)Fatty Acid SynthesisBy two enzyme system1. Acetyl-CoA carboxylase2. Fatty acid synthase complexAcetyl-CoA CarboxylaseConverts acetyl-CoA (2C) to malonyl-CoA in the presence of ATP.Acetyl-CoA carboxylase has a requirement for the B vitamin biotin.It is a multienzym...
1
Acetyl-CoA carboxylase
Hydroxyl-CoA dehydrogenase
Acetyl dehydrogenase
Pyruvate kinase
Biochemistry
Lipids
99d67a98-3952-49bd-9bee-2e551e245e25
multi
Maxillary sinus opens into which meatus?
Ans. c (Middle meatus). (Ref. Bhargaw, 5th ed.151)THE LATERAL NASAL WALL# It consists anteriorly of the nasal bone, frontal process of maxilla & the lacrimal bone.# Posterior to lacrimal bone, the lateral wall of nasal cavity is formed by ethmoid labyrinth, maxillary & inferior concha.# Perpendicular plate of palatine ...
3
Inferior
Superior
Middle
All
ENT
Nose and PNS
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multi
Which of the following is not true about Xenon anesthesia?
Ans. c. Slow induction and slow recovery Xenon anaesthesia is inert, non-explosive, environment friendly having low blood solubility with minimal cardiovascular side effects. Lower blood gas coefficient of Xenon results in rapid induction and recovery.Xenon Anesthesia* Xenon was isolated by William Ramsay (Nobel prize ...
3
Non explosive
Minimal cardiovascular side effects
Slow induction and slow recovery
Low blood gas solubility
Anaesthesia
Miscellaneous General Anesthesia
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multi
A male with azoospermia. On examination size of testis normal FSH normal testosterone normal. Most probable cause is:
Ans. is d, i.e. VAS obstructionSince all FSH, LH and Testosterone are normal therefore, it has to be an obstructive cause. Amongst the option, VAS obstruction is the only obstructive cause and hence our answer.
4
MAL descended testis
Klinefelter's syndrome
Kallmann's syndrome
VAS obstruction
Gynaecology & Obstetrics
Endometriosis and Infertility
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multi
a 40 yr old man underwent renal transplantation two months after transplantation he developed fever and features suggestive of bilateral diffuse interstitial pnuemonitis. what is causative agent ?
PERSONS WITH HIGH RISK OF CMV INFECTION : organ transplantation with malignant tumors who are recieving chemotherapy with hiv/aids viral excreation is icreased and prolonged diffuse interstitial pneumonia is common complication ref : ananthanaryana 9th ed
2
HSV
CMV
EBV
VZV
Microbiology
All India exam
e4012dca-8632-44f1-b40d-a28dd7cf8fe7
single
Infants acquire adult hemoglobin level at:
null
2
Birth
End of 1st year
Puberty
4 years
Physiology
null
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single
A child presented to the emergency depament with seizures. On examination oval hypopigmented macules were noted on the trunk, along with sub-normal IQ. What is the probable diagnosis?
Essentials of Diagnosis & Typical Features of Tuberous sclerosis: Facial angiofibromas or subungual fibromas. Often hypomelanotic macules, gingival fibromas. Retinal hamaomas. Coical tubers or subependymal glial nodules, often calcified. Renal angiomyolipomas. Seizures are the most common presenting symptom. Up to 20% ...
3
Neurofibromatosis
Sturge Weber
Tuberous sclerosis
Incontinentia Pigmenti
Pediatrics
null
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single