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Opioid tolerance develops to all of the following actions, except:
Ans. is 'a' i.e., Wasis Tolerance is exhibited to most actions of morphine except for miosis and constipation.
1
Miosis
Analgesia
Euphoria
Nausea and vomiting
Pharmacology
null
427e4fc4-c2f9-48bf-91ed-6a0f4f0b4889
multi
Which among the following help in folding of Proteins
Chaperones also called as heat shock proteins are auxillary proteins that assist in protein folding.
2
Proteosomes
Chaperones
Glycoproteins
Proteases
Biochemistry
null
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single
A 46- Years old female presented at the eye OPD in a hospital. Her vision in the right eye was 6/60 and in left eye 3/60. Under the National Programme for Control of Blindness, she will be classified as
Low Vision - Visual Acuity - NPCB, India Category 1 - <6/18 – 6/60 - Low Vision Category 2 - <6/60 – 3/60 - Economic Blindness Blindness Category 3 - <3/60 – 1/60 - Social Blindness Category 4 - <1/60 – PL+ - Manifest Blindness Category 5 - PL– - Absolute Blindness
1
Low vision
Socially blind
Economically blind
Normal vision
Social & Preventive Medicine
null
5fe3f11e-c2ee-4778-8e10-df40bcef5ac7
multi
Function of superior oblique muscle is:
The primary action of the superior oblique muscle is intorsion (internal rotation), the secondary action is depression (primarily in the adducted position) and the teiary action is abduction.
3
Intorsion, adduction and depression
Intorsion, abduction and elevation
Intorsion, abduction and depression
Extorsion, abduction and depression
Anatomy
null
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single
Which of the following inhalational agent can cause coronary steal phenomenon-
Isoflurane more than other inhalational agents increases coronary blood flow many times beyond that of the myocardial oxygen demand, thereby, creating potential for "Steel", steel is diversion of blood from a myocardial bed with limited or inadequate perfusion to a bed with more adequate perfusion.
1
Isoflurane
Sevoflurane
Desflurane
Halothane
Anaesthesia
Inhalational Anesthetic Agents
61471cf6-298e-4dd8-9e8e-80de22307e19
single
Screening are for trachoma is:
Ans. b. 1-9 years
2
Below 5 years school child only
1-9 years
9-14 years
5-15 years
Social & Preventive Medicine
null
e33e61bf-5461-44c4-bb94-42a9983afee1
single
Slowest conduction is seen in the following pa of the cardiac conducting system:
Depolarization initiated in the SA node spreads radially through the atria, then converges on the AV node. Atrial depolarization is complete in about 0.1 s. Because conduction in the AV node is slow, a delay of about 0.1 s (AV nodal delay) occurs before excitation spreads to the ventricles. This delay is shoened by sti...
3
SA node
Purkinje fibres
AV node
Bundle of his
Physiology
null
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single
What is the best stimulus for release of vasopressin
Best / most impoant stimulus for ADH - Hypeonicity Next - hypotension Water deficit | |extracellular osmolarity |Osmoreceptors | ADH secretion (posterior pituitary) | |Plasma ADH | H2O permeability in |distal tubules. Collecting ducts | |H2O reabsorption | |H2O excreted 1. | Osmolality / tonicity 2. Aerial baroreceptor...
3
Hypotonicity of extracellular fluid
Hypeension
Hypotension
Hypo-osmolality of extracellular fluid
Physiology
FMGE 2018
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single
Despite its "age," penicillin G remains the drug of choice in the treatment of infections caused by
Indications for the use of penicillin G are currently limited for a number of reasons. The drug has a narrow spectrum, is susceptible to beta-lactamases, and may cause hypersensitivity, and alternative antibiotics are available. However, penicillin G remains the drug of choice in syphilis, usually given IM as benzathin...
2
B. fragilis
T. pallidum
H. influenzae
E. coli
Pharmacology
Anti Microbial
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multi
Components separation technique in hernia helps by:
Ramirez first described the components separation technique. Components separation entails the creation of large subcutaneous flaps lateral to the fascial defect followed by incision of the external oblique muscles and, if necessary, incision of the posterior rectus sheath bilaterally. Fascial releases allow for primar...
2
Lesser infection
Decrease suture line tension
Lower recurrence
None of the above
Surgery
null
135abdc5-56ba-4a87-8d7e-7eb11e115fb0
multi
Volatile agent which causes most renal toxicity is
Methoxyflurane is most metabolized and produces more than 80 micromol/litre of flouride in blood. The amount of fluoride ions produced: Methoxyflurane: 50uM Sevoflurane: 20-30 uM Enflurane: 20uM Isoflurane and desflurane: 5uM
3
Ether
Isoflurane
Methoxyflurane
Sevoflurane
Anaesthesia
Inhalational Anesthetic Agents
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single
Bacteria with tuft of flagellae at one end are called -
Ans. is 'd' i.e., Lophotrichate Two projections from the cells are impoant in relation to bacteria? i) Flagella ii) Fimbriae Flagella Flagella are the organs of locomotion. All motile bacteria except for spirochetes possess flagella. Flagella are made up of protein antigen flagellin Though flagella of different genera ...
4
Monotrichate
Peritrichate
Bipolar
Lophotrichate
Microbiology
null
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multi
Positive ECG sign(s) of ischemia in Tread mill test is/ are-
Answer- B. Downsloping depression of the ST segment >0.1 mV below baselineThc ischemia ST:-segment respone generally is defined as flat or downsloping depression of the ST segmant >O.1 mVbelow baseline (i.e., tha PR segnent) and lasting longer than O.08s.Upsloping or junctional ST-segment changes are not considered cha...
2
Upsloping depression of the ST segment mV below baseline
Downsloping depression of the ST segment >0.1 mV below baseline
Junctional ST-segment
Tachycardia
Medicine
null
5407a05c-1275-4745-be90-89f96e7e92f9
single
The splenic aery usually follows a touous course along which of the following structure?
The splenic aery, the largest branch of the celiac trunk, follows a touous course posterior to the omental bursa, anterior to the left kidney, and along the superior border of the pancreas.
3
Left kidney
Greater curvature of the stomach
Pancreas
Transverse colon
Microbiology
All India exam
87ea4c1a-c47d-4b6f-8e0e-41bcb354c9b7
multi
Cetuxirnab (an EGFR antagonist) can be used in
Palliation in head Neck cancer Cetuximab is a monoclonal antibody that acts against EGFR (Epidermal growth factor receptor). EGFR is a signalling protein that normally controls cell division. In some cancers this is altered to cause uncontrolled cell division. Cetuximab attaches itself to EGFR and prevents the receptor...
1
Palliation in head and neck cancer
Anal canal ca
Gastric ca
Lung ca
Pharmacology
null
cc1228bc-3756-4b32-b8ce-2e41466a01d0
multi
Spanish windlass is an example of which of the following methods of crime?
In garrotting, a ligature is thrown over the neck of the victim and is quickly tightened by twisting it with a lever. In Spanish windlass, an iron collar is tightened by a screw. Ref: Essentials of Forensic Medicine and Toxicology by Narayan Reddy, 21st Edition, Page 300.
2
Bansdola
Garrotting
Throttling
Mugging
Forensic Medicine
null
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single
Investigation of choice for cryptococcosis is -
Ans. is 'b' i.e., India ink o C. neoformans is best demonstrated in CSF by direct microscopy. The capsule is seen as a clear halo around the yeast cells in unstained wet preparations of CSF mixed with a drop of India ink or nigrosine. Methenamine silver stain would be the best choice for a tissue sample.CRYPTOCOCCUS NE...
2
Culture
India ink
PCR
Acid faststain
Microbiology
Mycology
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single
Cause of nail bed infarctions a) H.D b) Wegener's granulomatosis c) Infective endocardities d) Surge strauss syndrome e) PAN
null
2
abc
bc
bd
cd
Medicine
null
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single
Demand of fetus for iron is evident after_____ weeks
Ans. c (25 weeks) (Ref. Nelson Textbook of Pediatrics 17th/pg. 545)IRON REQUIREMENT IN PREGNANCY# Mineral supplementation is not needed in healthy women.- The exception is iron.# The iron requirements of pregnancy are total about 1 gram.# Demand of fetus for iron is evident in last 12 weeks of pregnancy.
3
10
20
25
30
Gynaecology & Obstetrics
Miscellaneous (Gynae)
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All are true about the features of erythromelalgia , EXCEPT:
Erythromelalgia Syndrome of unknown etiology It is associated with thrombocytosis Manifested by erythema, warmth, and pain of the affected appendage and occasionally digital infarction. It usually respond to salicylates. Ref: Harrison, E-18,P-903
4
Unknown aetiology
Thrombocytosis is seen
Digital infarction is seen
Treatment is steroids
Medicine
null
5b4e1d67-7453-4e1e-a99c-c1d36bcae0ad
multi
Organism most frequently associated with urinary tract infections is
null
2
Neisseria gonorrhea
Escherichia coli
T-strain mycoplasma
Streptococcus fecalis
Microbiology
null
c0924c0d-30c1-4625-a2ce-fe939c358b92
single
The most impoant constituent in soda lime for reabsorption of CO2 in a closed circuit
Sodalime is most common Co2 absorbant . Indicators added to sodalime changes the color of sodalime . It contains 94% Ca(OH)2 , 5%NaOH,1% KOH.
3
Sodium hydroxide
Barium hydroxide
Calcium hydroxide
Potassium hydroxide
Anaesthesia
Anaesthetic equipments
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single
Osteomalacia is adverse effect of :
null
2
Primidone
Phenytoin
Carbamazepine
Valproic acid
Pharmacology
null
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single
Disease transmitted from men to animals:
Ans. b. Zooanthroponoses
2
Antropozoonoses
Zooanthroponoses
Amphixenoses
Aptozoonoses
Microbiology
null
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single
X–ray film should be taken in closed pneumothorax during-
Usual chest X-ray is PA view in full inspiration. For pneumothorax PA view in full expiration is the most appropriate view.
1
Deep expiration
Deep inspiration
In supine position
In lateral position
Radiology
null
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single
Lifespan of RBCs in premature neonate
Adults - 120 days. Term infant - 60 - 90 days. Premature neonate - 35 - 50 days.
4
120 days
60 days
90 days
40 days
Medicine
null
89a53b03-bd40-46f7-ba75-2c2296e31401
single
Which of the following is a Type 2 Hypersensitivity reaction?
Ref: Robbins E-Book, P 135* Choice A is type of type 4 Hypersensitivity reaction.* Choice C is type of type 3 Hypersensitivity reaction.* Choice D is type of type 4 Hypersensitivity reaction.Examples of type ii hypersensitivityDiseaseTarget antigenMechanism of diseaseClinicopathologic ManifestationsAutoimmune hemolytic...
2
Chronic Kidney Rejection episode
Autoimmune Hemolytic anaemia
Arthus reaction
Mitsuda reaction
Pathology
Immunity
a6f8902b-e77f-4277-a26c-acb65c83017f
single
Purple toe syndrome is associated with which of the following drugs?
null
1
Warfarin
Phenytoin
Theophylline
Thalidomide
Medicine
null
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single
The gene that predisposes to retinoblastoma is located at -
Robbins basic pathology 6th edition. Chapter Neoplasia. page no. 287. The mutations required to produce retinoblastoma involve Rb gene located on chromosome 13q14.
1
Chromosome 13q14
Chromosome 15q11
Chromosome 11p13
Chromosome 22q11
Pathology
General pathology
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single
A 23-year-old female presented with jaundice and pallor for 2 months. Her peripheral blood smear shows the presence of spherocytes. The most relevant investigation to arrive at a diagnosis is;
Ans. c. Coombs test (Ref: Robbins 9/e p643-644; Chandrasoma and Taylor 3/e p401)History of jaundice in a 23-year old female with pallor and spherocytes in peripheral blood points towards the diagnosis of autoimmune hemolytic anemia (AIHA). The diagnostic test for AIHA is the antiglobulin test (Coombs' test).Autoimmune ...
3
Reticulocyte count
Osmotic fragility test
Coombs test
Tests fro PNH
Pathology
Blood
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multi
A 57 year old male suffering from acute pancreatitis develops sudden onset breathlessness with a CVP< 18mmHg. The chest xray shows bilateral infiltrates. The possible diagnosis is
Answer- A. ARDSARDS CriteriaAcute, meaning onset over 1 week or less.Bilateral opacities consistent with pulmonary edema must be present and may be detected on CT or chest radiograph.PF ratio < 300 mmHg with a minimum of 5 cmH20 PEEP (or CPAP).CVP < l8 mmHg.
1
ARDS
Myocardial infarction
Congestive left hea failure
Pulmonary embolism
Surgery
null
a54478c8-ee11-4f3e-a20a-161888207f43
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Partner treatment is not required in all of the following except
Trichomoniasis is acquired by sexual route by tranmission of T.vaginalis and hence partner treatment is required.
4
Bacterial vaginosis
Herpes genitalis
Candidal vaginitis
Trichomoniasis
Dental
null
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multi
A 10-degree decrease in temperature causes decreases in cerebral metabolic rate by :
D i.e. 70%With each degree fall in temperature, the metabolic rate is reduced by 70%.So by reducing temperature by 10-degree celsius, the metabolic rate is reduced by 70%.Cerebra coex is protected for 10 mins at 30-degree celsius and for 1 hr at 15-degree celsius.
4
10%
30%
50%
70%
Physiology
null
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single
For diagnosis of Acute Rheumatic fever, essential is:
null
3
Prior h/o rheumatic fever
Recent sore throat infection
1 major and 2 minor criteria's
Erythema marginatum
Medicine
null
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single
The polysaccharide capsule of following bacteria has in role in their infectivity except
The polysaccharide capsule of Bordetella peusis has no significant role in its infectivity. Bordetella fresh cultures demonstrated capsules but its virulence is mainly toxin-mediated.
4
Haemophilus influenza
Neisseria meningitides
Streptococcus pneumoniae
Bordetella peussis
Microbiology
All India exam
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multi
Therapeutic aboion was accepted by -
Therapeutic aboion In 1970 the World Medical Association drew up a Statement on Therapeutic Aboion. This code, known as the Declaration of Oslo, was amended by the 35th World Medical Assembly, Venice, Italy in October 1983 and states: The first moral principle imposed upon the physician is respect of human life from it...
2
Declaration of Geneva (1948
Declaration of Oslo (1970)
Declaration of Helsinki
Declaration of Tokyo
Social & Preventive Medicine
Non communicable diseases
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single
IPC 94 related to
Section 94:- Act to which a person is compelled by threats Except murder, and other offences punishable with death, nothing is an offence which is done by a person who is compelled to do it by threats of instant death Explanations A perso seized by a gang of dacoits, and forced, by threat of instant death, to do a thin...
4
Consent in emergency situations
Criminal responsibility of an act done by a person < 7 years
Criminal responsibility of an act done by an intoxicated person
Criminal responsibility of an act Compelled by threats
Forensic Medicine
Legal sections
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single
Spinal shock is characterized by all of the following, Except :
Answer is A (Spastic paralysis): Spinal Shock is associated with Flaccid paralysis and not Spastic paralysis Spinal shock Flaccid Paralysis (complete motor paralysis) Areflexia Sensory loss (anesthesia to all modalities) Bladder Involvement (usually areflexic bladder with urinary retention)
1
Spastic paralysis
Flaccid paralysis
Urinary Bladder involvement
Areflexia
Medicine
null
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multi
Unequal division of the conus cordis resulting from anterior displacement of the conotruncal septum gives rise to
C. i.e. Tetralogy of Fallot
3
Persistent truncus aeriosus
Coarctation of aoa
Tetralogy of Fallot
Transposition of great vessels
Anatomy
null
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multi
Most common postprandial motility is seen in
It&;s sigmoid colon Tonic and phasic colonic motility and compliance of the transverse and sigmoid colon were therefore assessed using a combined barostat-manometry assembly in 22 healthy subjects. Measured colonic compliance was corrected by subtraction of the compliance of the closed barostat system. The mean (SEM) p...
4
Ascending colon
Transverse colons
Descending colon
Sigmoid colon
Physiology
G.I.T
9bc9e2d0-4924-451a-b2fd-faff1ef68f03
single
Which is not a tumor suppressor gene?
D i.e. RASGenes that promote autonomous cell growth in cancer cells are called oncogenes and their normal cellular counterpasQ are called proto-oncogenesQ. RAS is an oncogeneQ.Growth factorGrowth factor receptorsProteins involved in signaltransductionNuclear regulatory proteinsProtooncogeneEncodeProtooncogeneEncodeProt...
4
WT-1
Rb
p53
RAS
Biochemistry
null
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single
Which of the following is not a clinical presentation of Peripheral arterial occlusion
null
4
Pain
Pallor
Anesthesia
None of the above
Surgery
null
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multi
Frequent periodontal abscesses appear to be an important periodontal feature in
null
2
Nutrition deficiency
Diabetes Mellitus
Hormonal imbalance
Cardiovascular diseases
Dental
null
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single
The following are related to corpous luteum except
The estrogen attains a lower level and maintains a plateau curve as against a peak rise in follicular phase. Progesterone attains its highest peak about 8 days(22nd day of menstual cycle) after the LH peak Regression of corpus luteum is attrubuted to fall in LH level and rise in the level of estrogen and PGF2alpha. Ref...
4
Luteinised granulosa cells produce progesterone
Estrogen continues to be produced by the luteinised granulosa cells
Luteolysis is due to estrogen, PGF2a and endothelin
The peak steriod production is between 23 and 25th day
Gynaecology & Obstetrics
Reproductive physiology and hormones in females
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Best Diagnosis for Ectopic gastric mucosa of meckels diveiculum -
Ans is 'd' ie. Radionuclide scan "If a Meckels diveiculum is suspected because of repeated gastrointestinal haemorrhage the abdomen can be scanned after the injection of 99Tc-labelled peechnetate intravenously. This may localise heterotopic gastric mucosa revealing the site of a meckels diveiculum in 90% of cases." - B...
4
Fluoroscopy
Occult blood test in stool
Ultrasound abdomen
Radionuclide scan
Surgery
null
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single
Autoimmune hepatitis asso with -a) Anti LKM antibodyb) ANAc) ANCAd) SLA-antibody
null
2
acd
abd
abc
ab
Medicine
null
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single
A 40-yr-old female who is known as the case of ischemic heart disease (IHD) is diagnosed with having hypothyroidism. Which of the following would be the most appropriate line of management for her -
null
1
Start levothyroxine at low dose
Do not start levothyroxine
Use levothyroxine
Thyroid extract is a better option
Medicine
null
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A 2-year-old male is admitted to the hospital with testicular pain. Physical examination reveals an enlarged scrotum. An otoscope is placed beneath the lateral side of the scrotum and the testis is transilluminated through the scrotal sac. Which of the following best describes the signs observed in this patient?
(d) Source: GAS 448-451; GA 224-225 As seen in the photograph, the swollen scrotum contains mostly a clear fluid. Since hydrocele is the accumulation of fluid between the visceral and parietal layers of the tunica vaginalis, this condition best accounts for the findings in this patient.
4
Varicocele
Rectocele
Cystocele
Hydrocele
Anatomy
Abdomen & Pelvis
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single
The most life threatening complications of septic abortion includes:
Ans. is c, i.e. Respiratory distress syndromeRef. Dutta Obs. 7/e, p 164, 165; COGDT 10/e, p 987According to COGDT 10/e, p 987"The most common cause of death in patients with this condition is respiratory insufficiency secondary to ARDS."According to Williams Obs. 23/e, p 222"With severe sepsis syndrome, acute respirato...
3
Peritonitis
Renal failure
Respiratory distress syndrome
Septicemia
Gynaecology & Obstetrics
Abortion
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single
Plateau phase of cardiac cycle is due to -
Ans. is 'c' i.e., Ca2+ o Phase 0 (phase of rapid depolarization)- opening of fast sodium channels with Na4 influxo Phase 1 (initial phase of rapid repolarization)- closure of fast sodium channelso Phase 2 (plateu phase)- opening of voltage gated slow Ca++ channels with calcium influx.o Phase 3 (final repolarization)- o...
3
Na+
K+
Ca2+
Cl-
Physiology
Heart, Circulation, and Blood
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single
Stimulant drug is given to child for ?
Ans.D. ADHDStimulants (like methylphenidate, dextramphetamine) are the drugs of choice for ADHD.
4
Conduct disorder
Speech developmental disorder
Pervasive disorder
ADHD
Psychiatry
null
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single
CNS tumor seen in Von Hippel Lindau syndrome is-
null
2
Meningioma
Cerebellar hemangioblastoma
CNS lymphoma
Glioma
Medicine
null
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single
The food item associated with B.cereus emetic food-type poisoning is:
Option 1, 4 Food items associated: Diarrheal type - Meat, vegetables, dried beans, cereals. Emetic type - Rice (Chinese fried rice). 1. Bacillus cereus food poisoning is of two types. Emetic type and Diarrheal type abdominal cramps are common features in both. Other features are: a) Emetic Type: History of intake of fr...
4
Meat
Milk products
Canned food
Fried rice
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
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single
A child was operated for small intestine mass with intussusception and after the operation the tumor was diagnosed in histological section. Which is the most likely tumor associated?
SMALL-BOWEL NEOPLASM - MC tumor of small bowel: Leiomyoma > Adenoma - MC tumor of small bowel in children : Lymphoma - MC malignant tumor of small bowel : Adenocarcinoma >Carcinoid - MC site of small bowel malignancy, carcinoids, lymphoma: Ileum
3
Carcinoid
Villous adnoma
Lymphoma
Smooth muscle tumor
Surgery
Intestinal obstruction
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multi
For elimination of measles, vaccine Coverage should be (in successive brith cohart) -
Ans. is 'd' i.e., > 95% o WHO's measles elimination strategy comprises a three part vaccination strategy, i.e.:-i) Catch-up - One-time, nationwide vaccination campaign targeting usually all children aged 9 months to 14 years regardless of history of measles disease or vaccination status.ii) Keep-up - Routine services a...
4
>70%
> 80%
>90%
> 95%
Social & Preventive Medicine
Measles
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single
In LVH, SV1 +RV6 is more than mm
Ans. is 'c' i.e., 35 Arrhythmias by Kathryn Lewis p. 219] o In LVH, SV-1 plus RV-6 is more than 15 mm. To diagnose the left ventricular hyperophy on ECG one of the following criteria should be met :? The sokolow-lyon criteria is most often used - R in V, or V6 + 5 in V > 35 mm in men The cornell-criteria has different ...
3
25
30
35
45
Medicine
null
dc02803f-537e-49b3-8666-3dd6b043eef5
single
Serum marker of rickets is -
Ans. is 'b' i.e., Alkaline phosphataseo Amongst the given options, alkaline phosphatase is best because it is raised in all type of rickets.o The primary (Basic) investigations in a child of rickets are :?Serum calciumSerum phosphorusAlkaline phosphataseo If patient does not respond to calcium and Vit D therapy, second...
2
Acid phosphates
Alkaline phoshpatase
Decreased serum calcium
Urinary posphates
Pathology
null
d900b9c4-f6e0-47e3-96c4-ed4f81f41c73
single
The adjuvant used in IL PT vaccine is -
null
1
Al
Mg
Zn
Formaldehyde
Social & Preventive Medicine
null
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single
Which of the following is seen in Schwannoma?
Ans. c. Antoni A and Antoni B pattern (Ref: Robbins 9/e p257. 854, 8/e p1340)Antoni A and Antoni B pattern is seen in schwannoma.'Schwannoma: In the Antoni AQ pattern of growth, elongated cells with cytoplasmic processes are arranged in fascicles in areas of moderate to high cellularity and scant stromal matrix; the 'n...
3
Storiform pattern
Spindle cells
Antoni A and Antoni B pattern
Target cells
Pathology
Tumors
241dafe0-8b30-437b-9869-97f33228ea8e
single
RDA in infant of Vit A is -
- daily intake of vitamin A recommended by ICMR for infants is 350 mcg retinol. - daily intake of vitamin A recommended by ICMR for infants is 2800 mcg beta carotene. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:616 <\p>
1
350 g
450 g
600 g
1000 g
Social & Preventive Medicine
Nutrition and health
352d05ff-814f-4d68-9b59-9b541cce1b7b
single
Synthetic Orygen carrier is made up of_
Ans. is 'd' i.e., FlurineBlood doping is a form of fraudulent increase in the oxygen carrying capacity of a person, widely used to improve the aerobic capacity of athletes.
4
Iron
Bronze
Molybdenum
Flurine
Biochemistry
null
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single
Which of the following is not true for hemophilia A
null
4
Hemophilia A is due to deficiency of factor VIII
In hemophilia A females are carriers
Desmopressin is useful in the management of hemophilia A
Levels of factor VIII Less than 50% are associated with spontaneous hemorrhage
Pathology
null
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multi
At usual therapeutic doses (blood levels), expected effects of aspirin include which of the following?
Aspirin inhibits synthesis of prostaglandins that are impoant in the pathophysiology, signs, and symptoms of a host of inflammatory or ahritic states. It does so, of course, by inhibiting both COX-I and -2. Acetaminophen lacks this propey, and so acetaminophen is much less efficacious for managing inflammation. Aspirin...
1
Efficacy greater than acetaminophen as an anti-inflammatory agent
Efficacy less than acetaminophen for relieving simple headache pain
Inhibited growth, or killing, of bacteria that cause fever as a symptom of infection
Inhibition of leukotriene synthesis, protection against bronchopasm in asthmatics
Pharmacology
Autacoids
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single
The most impoant stimulus controlling the level of resting ventilation is:
The most impoant stimulus comes from the pH of the CSF on the central chemoreceptors. The other choices are incorrect: The effect of PO2 on the peripheral chemoreceptors under normoxic conditions is very small. Changes in PCO2 do affect the peripheral chemoreceptors, but the magnitude is less than that for the central ...
4
PO2 on peripheral chemoreceptors
PCO2 on peripheral chemoreceptors
pH on peripheral chemoreceptors
pH of CSF on central chemoreceptors
Physiology
Respiratory System Pa 2
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single
Intraocular calcification in eye in child -
Ans. is 'b' i.e., Retinoblastoma o In retinoblastoma, there are areas of necrosis and calcification.o In the presence of calcification, endophytic retinoblastoma gives the typical 'cottage cheese' appearance.
2
Toxocara
Retinoblastoma
Angiomatosis retinae
Malignant melanoma of choroid
Ophthalmology
Intra Ocular Tumour
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single
Treatment of carcinoma cervix stage MB include
Ans. a. Concurrent chemoradiation
1
Concurrent chemoradiation
Surgery
Neoadjuvant chemotherapy followed by radiotherapy
Only radiotherapy
Gynaecology & Obstetrics
null
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single
Predominant class of immunoglobulin during primary immune response is -
IgM antibodies appear early in the course of an infection and usually reappear, to a lesser extent, after fuher exposure. Ref: Ananthanarayan & Parkers textbook of microbiology 9th edition pg:98
3
IgA
IgE
IgM
IgG
Microbiology
Immunology
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single
All are true of actue rheumatic fever except ?
Ans. is 'c' i.e., Microthrombi in aeriole
3
Aschoff nodule in mycoacardium
Focal myocardial fiber necrosis
Microthrombi in aeriole
Lymphocytic myocarditis
Pathology
null
a74e8e10-d3b0-4404-9fc4-11e1beaec6c6
multi
Man with gynaecomatsia and infeility, cause?
Cimetidine (but not other H2 blockers) has antiandrogenic action. It displaces dihydrotestosterone from its cytoplasmic receptor. It also increases plasma prolactin and inhibits degradation of estradiol by liver. High doses given for long periods have produced gynaecomastia, loss of libido, impotence and temporary decr...
1
Cimetidine
Omeprazole
Erythromycin
Digitalis
Medicine
Endocrinology
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single
Wrong about dhatura seeds is ?
Ans. is 'd' i.e.,Convex smooth surface Features of Dhatura sees are :-Large & thickOdourlersKidney - shapedLaterally compressed and double edged at convex border (not smooth)Yellowisk brown Bitter
4
Kidney shaped
Odourless
Yellow brown
Convex smooth surface
Forensic Medicine
null
94027983-e50e-4229-a8f9-76658b3f4def
single
Predisposing factor for carcinoma vulva is all Except
The etiologic role of ceain viruses in carcinogenesis, paicularly high-risk HPV types 16 and 18, in these sites is well documented. Mention has already been made about the preceding stage of vulval epithelial disorders, paicularly squamous hyperplasia, in the development of these lesions. Ref: HARSH MOHAN TEXTBOOK OF P...
3
Smoking
HPV
Fibroepithelial polyp
Leukoplakia
Pathology
miscellaneous
33ed8a81-8b1b-4ef6-985c-46bc1bebb7a4
multi
Sharp pain is transmitted by which type of fibers
Sharp pain is transmitted by A delta nerve fibres Ref: guyton and hall textbook of medical physiology 12 edition page number: 698,699,700
3
Aa
Ab
Ad
C
Physiology
Nervous system
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single
Virulence factors for meningococci ?
Ans. is 'a' i.e., Capsule; 'b' i.e., Pili & 'c' i.e., Endotoxin The capsular polysaccharide - It is a major virulence factors - It has antiphagocytic and antibactericidal propeies. - Based on capsular polysaccharide, meningococci have been divided into serogroups. Outer membrane proteins - Pili - Facilitate adhesions -...
4
Capsule
Pili
Endotoxin
All
Microbiology
null
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multi
Modes of death are all except -
Modes of death are coma, syncope and asphyxia whereas molecular death is a type of death. Dr. Narayana Reddys Synopsis of Forensic Medicine & Toxicology 27th edition pg.66,67
4
Syncope
Coma
Asphyxia
Shock/molecular death
Forensic Medicine
Death and postmortem changes
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multi
Which is not an assisted reproduction technique:
Assisted reproductive technology (ART) is the technology used to achieve pregnancy in procedures such as fertility medication, in vitro fertilization and surrogacy. It is reproductive technology used primarily for infertility treatments and is also known as a fertility treatment. It mainly belongs to the field of repro...
4
GIFT
ZIFT
IVF and ET
Artificial insemination
Gynaecology & Obstetrics
null
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single
Nausea, Vomiting, Blue line on gums, Wrist/ foot drops, Pallor, Colic are manifestations of poisoning due to
Ans. (d) Inorganic leadRef: K. Park 23rd ed. / 807-808* Insomnia is caused by organic lead poisoning.* Organic lead poisoning causes CNS side effects while Inorganic lead poisoning causes non-CNS side effects.Due to Organic Lead (CNS effects)Due to Inorganic Lead (Non-CNS effects)* Insomnia* Mental confusion* Headache*...
4
Mercury
Arsenic
Organic lead
Inorganic lead
Social & Preventive Medicine
Occupational Health
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multi
Which of the following is MOST commonly affected in U.C
Ans. is 'b' i.e., Rectum The most common site of involvement in Ulcerative colitis is the rectum. Ulcerative colitis (involvement is limited to the colon) Ulcerative colitis typically stas in the rectum and may progress with continuous lesions (no skip lesions) in a retrograde manner to involve the entire colon (Pancol...
2
Cecum
Rectum
Sigmoid colon
Terminal leum
Medicine
null
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single
The differential diagnosis of lesion, histologically resembling giant cell tumour in the small bones of the hands or feet, includes all of the following except:
Ans. is 'b' i.e. Fibrosarcoma Histological differential diagnosis of Giant cell tumorGiant cell reparative granuloma (a benign reactive condition)Brown tumor of hyperparathyroidism Non-ossifying fibroma Benign fibrous histiocytoma Aneurysmal bone cyst Osteosarcoma with prominent giant cells.Metastatic ca with giant cel...
2
Aneursymal bone cyst
Fibrosarcoma
Osteosarcoma
Hyperparathyroidism
Orthopaedics
Giant Cell Tumor (GCT) or Osteoclastoma
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multi
Antemoem Abrasions can be confused with?
Postmoem ant bites on dead bodies may produce marks which simulate antemoem abrasions. Ref: Forensic Pathology By J.M. Di Maio, 2nd Edition, Page 196; Modi's Textbook of Medical Jurisprudence and Toxicology; Principles of Forensic Medicine and Toxicology By Rajesh Bardale, Page 174; Forensic Medicine and Toxicology By ...
2
Eczema
Ant bite marks
Chemical burn
Joule burn
Forensic Medicine
null
707d2633-0524-40af-8fc7-59e7eed396cc
single
Pyomyositis is caused by which of the following?
Pyomyositis is an acute bacterial infection of the skeletal muscle caused by Staphylococcus aureus. It may be primary or secondary to a penetrating injury or contiguous anatomic infection. It typically affects the major muscles of the lower extremity and the gluteal muscles. Patients usually presents with pain, tendern...
1
Streptococcus aureus
Streptococcus pneumonia
Salmonella typhi
E. coli
Microbiology
null
f339161b-3870-4f2b-bdd5-7d069376ca25
single
Increased intracranial tension is seen with:
ANSWER: (A) KetamineREF: Morgans clinical anesthesia 3rd edition page 141"Remember always Ketamine increases not only intracranial pressure but all the pressures of the body, like blood pressure, intraocular pressure, and intragastric pressure"Agents that increase intracranial pressure (ICP) can be remembered as Mnemon...
1
Ketamine
Thiopentone
Halothane
Propofol
Anaesthesia
Anesthesia for Neurosurgery
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single
Which of the following is the most common functioning pancreatic islet cell tumour ?
null
3
Gastrinoma
Glucagonoma
Insulinoma
Vipoma
Medicine
null
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single
Prophylaxis with Cotrimoxazole is recommended in the following situation except –
A) Cotrimoxazole prophylaxis in HIV exposed infant is recommended for :- All HIV exposed infants (started at 4-6 weeks of age and continued until HIV infection can be excluded). HIV exposed breast feeding children of any age (Prophylaxis should be continued until HIV infection can be excluded at least six weeks after ...
1
All symptomatic HIV infected children > 5 years of age irrespective of CD4
All HIV exposed infants till HIV infection can be ruled out
All HIV infected infants less than 1 year age irrespective of symptoms or CD4 counts
As secondary prophylaxis after initial treatment for pneumocystis carini pnetunonia
Pediatrics
null
682c0763-848a-460b-a7fe-2119fed6a78d
multi
True regarding foetal trunk movements in third trimester NOT RELATED - GYN
By term, the normal number of generalized movements is reduced as a result of cerebral maturation processes, rather than as a consequence of the decrease in the amniotic fluid volume.
1
Increases towards term
Decreases towards term
Remain unchanged
None of the above
Pharmacology
All India exam
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multi
MELD score includes A/E
Ans. is 'a' i.e., Sr. creatinine The Model for End-stage Liver Disese (MELD) is a prospectively developed and validated chronic liver disease severity scoring system that uses a patient's laboratory values for - Li Serum bilirubin Serum creatinine The international normalized ratio (INR) for prothrombin time to predict...
1
Sr. creatinine
Transaminase
Albumin
Alkaline phosphatase
Medicine
null
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single
Visual Hallucinations are commonly seen in :
Frontotemporal dementia is Characterized by Visual Hallucinations.
3
Alzheimer's disease
Lewy body dementia
Frontotemporal dementia
Vascular dementia
Psychiatry
null
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multi
All of the following drugs are useful in detrusor instability except:
Ans. (D) Duloxetine(Ref: Principles of Pharmacology, 1/e p157, 159; KDT 8th/e p124)Anticholinergic drugs decrease the motility of urinary tract and thus may result in urinary retention (therefore contra-indicated in BHP).Dicyclomine, flavoxate and oxybutynin are useful for the treatment of urinary incontinence due to d...
4
Solefenacin
Tolterodine
Flavoxate
Duloxetine
Pharmacology
A.N.S.
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multi
Fatal level of ethanol in blood: NIMHAS 13
Ans. 300-400 mg/dl
3
100-200 mg/dl
200-300 mg/dl
300-400 mg/dl
> 500 mg/dl
Medicine
null
70ca4793-b90a-4ef7-b607-5242d7684e81
single
Tylectomy literally means-
Lumpectomy (Tylectomy): Surgical procedure designed to remove a discrete lump.
1
Excision of a lump
Excision of LN
Excision of breast
Excision of skin
Surgery
null
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multi
A 24-year old man falls on the ground when he is struck in the right temple by a baseball. While being driven to the hospital, he lapses into coma. He is unresponsive with the dilated right pupil when he reaches the emergency department. The most important step in initial management is :
Coma with a dilated pupil after a lucid interval following a head injury must be assumed to represent an epidural hematoma. Emergency evacuation of the clot without time-consuming studies is vital to restore cerebral function. CT scan is done with a patient in less critical condition.
1
Craniotomy
CT scan of the head
X-ray of the skull and cervical spine
Doppler ultrasound examination of the neck
Surgery
null
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multi
Burkitt's Lymphoma is associated with which of the following viruses
Answer is A (t(8:14)) 'Demonstration of very high proliferative fraction and the presence of the t (8; 14) or one of its variants t (2; 8) or t(8:22) can be confirmatory of Burkitt's lymphoma /leukemia'
1
EBV
HTLV-1
HHV- 8
Adenovirus
Medicine
null
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single
Small fiber neuropathy is seen in?
Small unmyelinated peripheral nerve fibers, Categorized as C fibers, In skin and organs. Innervate the skin (somatic fibers) , Help to control autonomic function. Causes of Small Fiber Neuropathy: 1. Diabetes mellitus 2. Leprosy 3. Amyloidosis 4. Tangier's disease 5. Sjogren syndrome 6. HIV 7. Sarcoidosis
1
HIV
Vitamin B12 deficiency
AIP
Cisplatin toxicity
Medicine
Channelopathies and Neuropathies
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multi
All of the following are contents of Posterior Mediastinum except
Ascending Aoa is present in middle mediastinum.Contents of posterior mediastinum are1) Oesophagus 2) Aeries: Descending thoracic aoa and its branches.3) Veins: (i) Azygos vein, (ii) Hemiazygos vein, and (iii) Accessory hemiazygos vein.4) Nerves: (i) Vagus, (ii) Splanchnic nerves5) Lymph nodes and lymphatics (i) Posteri...
1
Ascending Aoa
Hemiazygous vein
Thoracic duct
Oesophagus
Anatomy
Thorax
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multi
Transfer of DNA from one bacterium to other by a bacteriophage is known as
Ans. c (Transduction). (Ref. Textbook of Microbiology by Anantanarayan, 6th/53)TRANSMISSION OF GENETIC MATERIAL IN BACTERIA IS BY:# Transformation:- Transfer of genetic information through agency of free DNA.# Transduction:- Transfer of a portion of DNA from one bacteria to another by transduction phase.- It is not con...
3
Formation
Conjugation
Transduction
Transcription
Microbiology
General
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single
Pericardial effusion is best diagnosed by: September 2009
Ans. B: Echocardiography Echocardiography is the imaging modality of choice for the diagnosis of pericardial effusion. Most impoantly, the contribution of pericardial effusion to overall cardiac enlargement and the relative roles of tamponade and myocardial dysfunction to altered hemodynamics can be evaluated with echo...
2
Chest X-ray
Echocardiography
ECG
Angiography
Medicine
null
71fba271-3625-49f5-bfe6-f2215b3012eb
single
Which of the following opens directly into right atrium?
Following opens into right atrium -        Superior vena cava -        Inferior vena cava -        Coronary sinus -        Venae cordis minimae -        Anterior cardiac vein -        Right marginal vein
1
Anterior cardiac vein
Oblique vein
Middle cardiac vein
Great cardiac vein
Anatomy
null
fdb40ab1-e0c0-405d-a8f3-73f52b787f19
single
Which of the following is caused by congenital A-17 hydroxylase deficiency:
17 -hydroxylase (17 -OH) deficiency syndrome is a rare genetic disorder of steroid biosynthesis causing decreased production of glucocoicoids and sex steroids and increased synthesis of mineralocoicoid precursors. Reduced or absent levels of both gonadal and adrenal sex hormones result in sexual infantilism in 46, XX f...
4
hypercalemia
Hyperkalemia
Hermaphroditism
Hypeension
Pediatrics
All India exam
00c34add-87f1-499b-9d06-67d606f2d8c7
single
Conductive hearing loss is seen in all of the following except:
Endolymphatic hydrops i.e menieres disease leads to SNHL and not conductive hearing loss.
3
Otosclerosis
Otitis media with effusion
Endolymphatic hydrops
Suppurative otitis media
ENT
null
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multi
Main aerial supply of the tonsil is from :
A i.e. Facial aery
1
Facial aery
Ascending pharyngeal aery
Palatine aery
Palatine aery
Anatomy
null
564c25c2-e153-4b70-98e6-ea848af95093
single
Koenen's tumor associated with ?
Ans. is 'a' i.e., Tuberous sclerosis Koenen's periungual fibroma is seen in tuberous sclerosis
1
Tuberous sclerosis
Neurofibromatosis
Psoriasis
Alopecia aerata
Skin
null
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single