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A 5-year-old girl came with history of progressively increasing pallor since bih and hepatosplenomegaly. Which is the most relevant test for achieving diagnosis?
Progressive increasing pallor along with hepatosplenomegaly in a five-year-old girl is consistent with a diagnosis of thalassemia. (Thalassemia intermedia) 'Hemoglobin electrophoresis' is the test of choice of diagnosing this condition and hence is the option of choice here.
1
Hb electrophoresis
Peripheral smear examination
Osmo c fragility test
Bone marrow examination
Physiology
All India exam
055fc135-e603-4705-8665-dfdb50c133ce
multi
Creatine is made up of all, except -
Ans. is 'b' i.e., Alanine o Creatine and creatinine are not amino acids, but specialized products of amino acids. Creatine is synthesized from glycine, arginine and methionine. Synthesis start with formation of guanidoacetate from glycine and arginine in kidney. Further reactions takes place in liver and muscle.Thus, b...
2
Glycine
Alanine
Methionine
Arginine
Biochemistry
Miscellaneous (Structure & Function of Proteins)
591077e8-d0f6-4b9c-a74a-4e2ad01eadda
multi
which of the following class antidepressent used in the management of smoking sessation
NDRI * IMPOANCE Anti-depressant which does not deal with serotonin neurotransmission Also called as Zyban * MECHANISM Prevents reuptake of nor adrenaline and dopamine * DRUGS Bupropion * USE ADHD SMOKING CESSATION HYPOACTIVE SEXUAL DESIRE DISORDER * SIDE EFFECTS seizures Ref. kaplon and sadock, synopsis of psychiatry, ...
3
SSRI
MAOI
NDRI
RIMA
Psychiatry
Pharmacotherapy in psychiatry
415f223c-c54c-4ee0-87bd-4dbcefe19c8e
single
False statement about bilirubin is
Bilirubin transpo: Bilirubin circulates in plasma noncovalently, bound to albumin. It is taken up across the sinusoidal membrane of hepatocytes by a carrier-mediated mechanism. Bilirubin uptake is mediated by a liver-specific sinusoidal organic anion transpo protein, (OATP1B1, SLC21A6) Then bilirubin is directed by cyt...
3
Bilirubin circulating in plasma by covalently binding with albumin
Bilirubin is taken up across the sinusoidal (basolateral) membrane of hepatocytes by a carrier-mediated mechanism
Conjugated bilirubin in plasma undergoes stool elimination
Conjugated bilirubin is then directed primarily toward the canalicular (apical) membrane
Medicine
null
b2d73430-2b7d-4807-844f-10beab7ab25c
multi
The cause of death in cyanide poisoning is
Anoxic anoxia: caused by a complete lack of oxygen to the brain. It occurs when a person is in an environment without enough oxygen, such as at high altitudes.Anemic anoxia: Anoxia due to anemia is not severe at rest unless hemoglobin deficiency is marked. However anemic patients may have considerable difficulty during...
3
Anoxic anoxia
Anaemic anoxia
Histotoxic anoxia
Stagnant anoxia
Physiology
Respiratory system
d775a7a2-af6d-4bdc-8d1e-54f4badf00e8
single
Which of the following chromosomal abnormalities is most likely to cause mental retardation?
Ans. D. Trisomy 21An extra chromosome 21 is the most common genetic abnormality found in Down syndrome, and the abnormality most likely to cause mental retardation. Abnormalities in autosomal chromosomes are, in general, associated with mental retardation. The chromosomal aberration represented by 46 chromosomes with f...
4
Klinefelter's syndrome
Fusion of chromosomes 21 and 15
Turner's syndrome
Trisomy 21
Psychiatry
Child Psychiatry
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single
Which pa of subclan aery is affected by stenosis is:
Most common etiology of subclan stenosis is atherosclerosis, and it mostly affects the ostium or proximal pa of subclan aery. Ref: Peripheral and Cerebrovascular Intervention By Deepak L. Bhatt, Page 102
1
First pa
Second pa
Third pa
All pas are equally affected
Surgery
null
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multi
Valley fever or desse rheumatism is caused by
Coccidioides causes primary pulmonary disease which can be mild influenza-like fever ( valley fever) to severe pneumonia. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition
1
Coccidioides
Cladosporium
Phialophora
Histoplasma
Microbiology
mycology
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multi
Ductus arteriosus obliterates to form:
Ans. D. Ligamentum arteriosumChanges in Fetal Circulation Just after Birth After birth, the placenta is separated from newborn and lung startsoxygenating the blood, i.e., respiration is established. Now the oxygenated blood comes to heart from the lungs. As a result, the following changes take place in fetal circulatio...
4
Ligamentum venosum
Ligamentum teres
Ligamentum hepatis
Ligamentum arteriosum
Anatomy
Embryology
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single
What is the likely source of infection for Pus from sphenoethmoidal recess?
Ans: (a) Sphenoid sinusRef: Dhingra's ENT 6th ed. /138* Spheno ethmoidal recess is situmated above the superior turbine. Sphenoid sinus opens into is* Sphenoid sinus. It has an anterior part & posterior part.Anterior Part: roof related to the olfactory tract, optic chiasma, frontal lobe while the lateral wall is relate...
1
Sphenoid sinus
Ethmoidal sinus
Maxillary sinus
Frontal sinus
ENT
Paranasal Sinuses
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single
The above nail changes are seen in:
Salmon patch or translucent oil drop like discoloration beneath nail plate is calssically seen in Psoraisis.
3
Lichen planus
Alopecia areata
Psoriasis
Onycholysis
Dental
null
5d1e77c5-3bd1-45a2-a784-3ad9d4db8a9a
multi
Resource person for Training ofASHA are
Ans. is 'b i.e., AWW and ANM o Angan-Wadi Workers (AWW) and Auxiliary Nurse Midwife (ANM) act as resource persons far training of ASHA (Accredited Social Health Activist).
2
AWW and MPW
AWW and ANM
MPW and ANM
ANM and MO
Social & Preventive Medicine
null
b1ed28c9-87c0-4759-942d-919cfd83f045
single
Most common site of tuberculosis of spine is?
Ans. (a) ThoracolumbarRef: Apley 387-389, Schwartz's Principles of Surgery 9th ed ch-29 M Tuli 3rded p-192
1
Thoracolumbar
Sacral
Cervical
Lumbosacral
Orthopaedics
Skeletal Infections
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single
Advantages of wrought gold alloy clasp wires over cast gold clasps of the same cross sectional area are
null
3
Coarser grain
Higher yield strength
Greater flexibility
More accurate adaptation to the tooth
Dental
null
736eb304-cd67-4f89-acf4-91cde8a21911
multi
Angiography is the investigation of choice in:
Ans. Central serous retinopathy
4
Posterior vitreous detachment
Rhegmatogenous retinal detachment
Retinoschisis
Central serous retinopathy
Ophthalmology
null
b378fd4c-42e8-4169-8b23-d33b6f2b39a4
single
Half life of insulin is -
Ans. is 'a' i.e., 5 min o The half-life of insulin in the circulation in humans is about 5 min. Insulin binds to insulin receptors, and some is internalized. It is destroyed by proteases in the endosomes formed by the endocytotic process.
1
5min
1hr
12hr
24hr
Physiology
Endocrinology metabolism
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single
Cultivable (in vitro) hepatitis virus is -
HAV can be grown in some human and simian cell cultures and is the only human hepatitis virus which can be cultivated in vitro. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-541
1
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Microbiology
Virology
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single
High inguinal orchiectomy specimen showed teratoma testis with involvement of epididymis; stage is
null
1
T 1
T 2
T 3
T 4 b
Surgery
null
3ca27d0a-c2ba-42fd-8119-c72cc8883e41
single
Development of heart is from which of the following:
ANS. DThere has been a rising trend of asking embryology images in AIIMS. May session had asked the development of nucleus pulposus (Answer was notochord). Development of cerebral cortexDevelopment of palate and anomalies of it* Midline cleft lip: Due to non-fusion of 2 median nasal process* Harelip (not midline): Due ...
4
Pharyngeal arches
Forebrain
Upper limb
Heart
Anatomy
Embryology
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single
Which of the following mutations in a tumor suppressor agent causes breast carcinoma
Ref Robbins 9/e p294 Mutation in p53 tumor suppressor gene is strongly associated with breast cancer,as well as many other sarcomas and carcinomas .this condition is called li Fraumeni syndrome Li-Fraumeni syndrome is a rare, autosomal dominant, hereditary disorder that pre-disposes carriers to cancer development This ...
2
P43
P53
P73
P83
Anatomy
General anatomy
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single
Increased permeability in acute inflammation is due to
Formation of endothelial gaps in venules, i.e. immediate transient response is the most common mechanism causing increased vascular permeability in acute inflammation, Mediators involved in this mechanism are i. Immediate (more important): Histamine, bradykinin, leukotrienes, neuropeptide substance P. ii. Somewhat del...
1
Histamine
IL-2
TGF-p
FGF
Pathology
null
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Iodine gives red colour with
Amylose: Gives blue with iodine testAmylopectin: Gives reddish violet with iodine testGlycogen: With iodine-: deep red colour
4
Starch
Dextrin
Inulin
Glycogen
Biochemistry
All India exam
bbddee4f-f497-406e-ac27-7ea808c90543
single
Essential fatty acid -
Ans. is 'a' i.e., Linoleic acid o The three polyunsaturatedfatty acids (PUFAs), namely, linoleic acidQ linolenic acidQ, and arachidonic acidQ are called essential fatty acids.o They are called essential fatty acids because human beings require these fatty acids but cannot synthesize themQ,o Humans lack the enzymes to i...
1
Linoleic acid
Palmitoleic acid
Oleic acid
Arachidonic acid
Biochemistry
Biosynthesis of Fatty Acids and Eicosanoids
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Centrally acting anti hypertensive drug is -
Ans. is 'b' i.e., Methyl Dopa Centrally Aeting Svmpatholvticso These drugs reduce sympathetic outflow from vesopressor centers in brainstem. Examples are :1 .Clonidine3.Guanabenz5. Rilmenidine2. Methyldopa4. Guanfacine6. MoxonidineClonidineo It acts (partial agonist) on a, receptors, especially a2A in brainstem - Stimu...
2
Phenoxybenzamine
Methyl dopa
Propanolol
Prazosin
Pharmacology
Anti-Hypertensive
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multi
Local anaesthetics act by?
Ans. is 'a' i.e., Na channel inhibition inside gate Local anesthetics act by inhibiting Na' channels from inside. Mechanism of action of LA Local anaesthetics block generation and conduction of nerve impulse at all pa of neuron where they come in contact, without causing structural damage. Thus not only sensory but mot...
1
Na channel inhibition inside gate
Na channel inhibition outside gate
K channel inhibition inside gate
K channel inhibition outside gate
Anaesthesia
null
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single
APACHE II score involves all except?
Ans. (d) Serum amylaseRef-.Harrison 19th edition, Chapter 267* Acute Physiology and Chronic Health Evaluation II is the most commonly used Severity of illness scoring system in America* Age, type of ICU admission (after elective surgery vs. nonsurgical or after emergency surgery), a chronic health problem score, and 12...
4
GCS
Arterial PH
Mean BP
Serum amylase
Medicine
C.N.S.
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multi
Extensive surgical debridement, decompression or amputation may be indicated in the following clinical setting except
Superficial thrombophlebitis management This is a superficial venous thrombosis. An abnormal endothelium is a much more common precipitating factor than in most DVTs. Common causes include external trauma (especially to varicose veins), venepunctures and infusions of hyperosmolar solutions and drugs. The presence of an...
2
Progressive synergistic gangrene
Acute thrombophlebitis
Acute haemolytic streptococcal cellulitis
Acute rhabdomyolysis
Surgery
Urology
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multi
Acetyl CoA is used for synthesis of following, except :
Acetyl-CoA is the third branch point of primary metabolic control, and coordinates carbohydrate, ketone, and fat/lipid pathways.Acetyl-CoA is the product of carbohydrate, protein, and lipid catabolism.Acetyl-CoA is a substrate for the citric acid cycle and can be oxidized to generate energy. It is not used for the synt...
4
Carbohydrates
Ketone bodies
Cholesterol
Non-ketogenic amino acids only
Biochemistry
null
2dfc018a-a08b-442b-b15d-97089cadfd28
multi
All of the following are absolute indications for tonsillectomy, except
Recurrent throat infections, peritonsillar abcess, tonsillitis causing febrile seizures, hyperophy of tonsils causing sleep apnoea or speech interference and any suspicion of malignancy are absolute indications for tonsillectomy.
4
Recurrent attacks
Peritonsillar abscess
Suspected malignancy
Acute tonsillitis
ENT
null
045e8869-370f-448f-ab38-51026b71a102
multi
Which of the following is found in secondary granules of neutrophils?
Neutrophils have two main types of granules The smaller specific (secondary) granules contain lysozyme, collagenase, gelatinase, lactoferrin, plasminogen activator, histaminase, and alkaline phosphatase. The larger azurophil (primary) granules contain myeloperoxidase, bactericidal factors (such as defensins), acid hydro...
4
Catalase
Gangliosidase
Proteolytic enzyme
Lactoferrin
Pathology
null
7d79045b-b41e-43a2-a60a-fc716e0146bc
single
Deep peroneal nerve doesn't supply -
Muscles of anterior compartment of leg are supplied by deep peroneal nerve. Muscles of lateral compartment of leg (Peroneus longus, peroneus brevis) are supplied by superficial peroneal nerve.
4
Tibialis anterior
Extensor hallucis longus
Extensor digitorum longus
Peroneus brevis
Anatomy
null
3139ed09-d99e-4d07-9dd4-4e6970ffb50c
multi
In carcinoma base of tongue pain is referred to ear through
Ans. is 'c' i.e., Glossopharyngeal Referred otalgiao As ear receives nerve supply from Vth (auriculotemporal branch), IXth (tympanic branch) and IXth (auricular branch) cranial nerves; and from C2 (lesser occipital) and C2 and C3 (greater auricular), pain may be referred from these remote areas.Via IXth cranial nerveDe...
3
Trochlea
Olfactory
Glossopharyngeal
Abducent
Unknown
null
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single
Clinical feature(s) seen in Kwashiorkar is/are _______
Kwashiorkar is a form of severe acute malnutrition (SAM) characterized by edema and apathy. Edema is most likely to appear first on the feet and then in the lower legs. It can develop into generalized edema affecting the hands, arms and face. Moon face Skin changes include depigmentation of skin, dermatoses, dark, crac...
4
Loose wrinkled skin
Hunger pangs
Simian facies
Edema and apathy
Pediatrics
Nutrition
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A 25 year old male presented with pigmentation of nose and pinna. After voiding, his urine becomes dark. His spine is most likely to show-
Ans. is 'd' i.e., Calcification of disc Clinical features of the patient suggests the diagnosis of AlkaptonuriaClinical problems arise from degenerative changes in articular cartilage with the development of ochronotic arthritis and from calcification of intervertebral discsOther clinical features areScleral pigmentati...
4
Atlantoaxial subluxation
Spondyloptosis
Basilar invagination
Calcification of disc
Medicine
Immunology and Rheumatology
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Following is a doctrine related to negligence -
Ans. is 'a' i.e. Therapeutic misadventureo Diagnostic or Therapeutic misadventure is the occurrence of misadventure causing injury or death of the patient due to inherent risk of procedure or drug, e.g. adverse effects of a drug. It is unintentional.Doctrines related with negligence1) Resp Ipsa Loquitar (fact speaks fo...
1
Therapeutic misadventure
Privileged communication
Professional secrecy
All of the above
Forensic Medicine
Medical Negligence
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multi
On one side kidney is normal, while other side kidney is contracted with scar, what is the most probable diagnosis?
null
1
Chronic pyelonephritis
Polycystic kidney
Renal artery stenosis
Tuberculosis of kidney
Pathology
null
273c5c46-008c-4682-ba1a-caff1e7f8bd4
single
If amphotericin B is administered, the patient should be premedicated with :
null
4
Diphenhydramine
Ibuprofen
Prednisone
Any of the above
Pharmacology
null
fd13bbce-af48-4b91-a89f-e543ee73ceda
multi
Cytokine causing fever -
Ans. is 'a' i.e., IL-6 Pyrogeneso Pyrogenes are substances that cause fever,o Pyrogens may be exogenous or endogenousExogenous - Bacterial toxinsEndogenous - IL-1, TNF-a, IL-6, Interferons, Ciliory's neurotropic factoro These pyrogenes increase the level of PGE2 in the hypothalamus that elevates the thermoregulatory se...
1
IL-6
IFN-y
IL-18
EL-4
Pathology
Cellular Pathology
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single
Best diagnosed with USG at first trimester
Ans. A. Anencephaly Ref: DC Dutta's obstetric p408ExplanationIn the first half of pregnancy, the diagnosis of anencephaly is made by elevated alpha-fetoprotein in amniotic fluid and confirmed by sonography.Question not recalled properly: Imerslund-Grasbeck syndrome, its cause was asked.ExplanationCaused by low levels o...
1
Anencephaly
NT defects
Meningocele
Option not recalled
Gynaecology & Obstetrics
Diagnosis in Obstetrics
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multi
GFR is increased when -
D i.e., Increased renal blood flow
4
Plasma oncotic pressure is increased
Glomerular hydrostatic pressure is decreased
Tubular hydrostatic pressure is increased
increased renal blood blow
Physiology
null
455b0fb6-8f82-45ec-8b73-18dae822ad64
single
What is the investigation going on in Ophthalmology examination
Goldmann Applanation tonometry Gold standard. Based on Imbe Fick law. If cornea is thinner than reading is falsely low. If cornea is thicker, it is falsely high. Applanation tonometry Other Options Pachymetry: Corneal thickness Biometry: Calculation of Power of IOL to be implanted after cataract surgery LASER interfero...
2
Pachymetry
Tonometry
Biometry
LASER interferometry
Ophthalmology
Glaucoma
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The most common site of nasopharyngeal carcinoma is
The commonest site of origin of nasopharyngeal carcinoma is fossa of Rosenmuller in the lateral wall of the nasopharynx. Tumor can spread to the following areas:- Cranium through foramen lacerum & ovale → cranial nerves involvement (III, IV, V, VI); facial pain, and ophthalmic symptoms. Parapharyngeal space → cranial ...
1
Fossa of Rosenmuller
Palatine tonsils
Antrochoanal region
Valleculae
ENT
null
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multi
All of them are true about ERG except
Electroretinography (ERG) is the record of changes in the resting potential of the eye induced by a flash of light. Components of normal electroretinogram (ERG) a-wave. It is a negative wave possibly arising from the rods and cones (photoreceptors). b-wave. It is a large positive wave which is generated by Muller's cel...
4
Measures the potential difference of the neurosensory layer of retina
The negative A wave is produced by the hyperpolarization of the photoreceptors
The positive B wave is due to the bipolar and Muller's cells
Flash ERG is a good for detection of macular diseases
Ophthalmology
Ophthalmology Q Bank
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multi
Contracted socket occurs because of all the following except:
Ans. Loss of fatty tissue during surgery of enucleation
4
Chronic low grade infection
Chronic mechanical irritation
Irradiation
Loss of fatty tissue during surgery of enucleation
Ophthalmology
null
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In a population of 100 prevalence of candida glabrata was found to be 80%. If the investigator has to repeat the prevalence with 95% confidence what will the prevalence be
Confidence Intervals for Population proportions (For 95% Confidence) CI = P + 2 SEP = P + 2 √pq/n Here, P=0.80 (80%); p=0.80; q= 1-p = 1-0.80 = 0.20; n=100 CI = 0.80 + 2 √0.8*0.2/100 = 0.80 + 0.08 = 0.72, 0.88 (72%, 88%)
2
78-82%
72-88%
76-84%
74-86%
Social & Preventive Medicine
null
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Trendelenburg test is positive in which of the following condition:
In L5 S1 PIVD Superior gluteal nerve is effected which supplies the abductors of hip i.e Gluteus medius and minimus causes trendelenburg gait. TRENDELENBURG SIGN Normally when the body weight is suppoed on one limb, the glutei (medius and minimus) of the suppoed side contract and raise the opposite and unsuppoed side o...
2
L3 L4 PIVD
L5 S1 PIVD
Synovitis of the hip
Femoroacetabular Impingement Syndrome
Orthopaedics
Pelvis and Hip Injury
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Primitive streak develops from?
Around day 14, the epiblast cells form primitive streak,. Notochord is formed by the mesoderm cells developed by epiblast cells.
3
Mesoderm
Hypoblast
Epiblast
Neural plate
Anatomy
JIPMER 2017
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Fluid flow in and out of the dentinal tubules is proportional to the tubule diameter by:
Fluid flow in dentin tubules follows Poiseuille’s law as all tubular structures:
4
Third power of the diameter
Sixth power of the diameter
Square of diameter
Fourth power of diameter
Dental
null
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single
Primary closure of incised wounds must be done within:
WOUNDS CAN BE CLOSED BY Primary suture:   - Clean wounds   - Selected contaminated wounds after thorough wound toileting and debridement Delayed primary suture:  - Heavily contaminated wounds  - Wounds in which wound toileting has been delayed for 6-8 hours Left open to heal by secondary closure
3
2 hours
4 hours
6 hours
12 hours
Surgery
null
ec8c9812-a433-4583-abd0-17ac263f9e1c
single
Dose of MgSO4 in asthma is
Bronchodilators Bronchodilator therapy is central to the management of breathlessness. The inhaled route is preferred and a number of different agents delivered by a variety of devices are available. Choice should be informed by patient preference and inhaler assessment. Sho-acting bronchodilators may be used for patie...
2
8 g i.v. over 20 minutes
2g infused over 20 minutes
2g i.v. over 40 minute
6 g i.V. over 40 minutes
Medicine
Respiratory system
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A 10-year-old boy has a fracture of the femur. The biochemical evaluation revealed Hb 11.5 gm/dl and ESR 18 mm 1 hour, serum calcium 12.8 mg/dl, serum phosphorus 2.3 mg/dl, alkaline phosphatase 28 KA units and blood urea 32 mg/dl. Which of the following is the most probable diagnosis in his case?
null
3
Nutritional rickets
Renal rickets
Hyperparathyroidism
Skeletal dysplasia
Medicine
null
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single
Trendelenburg test is positive due to injury to which of the following nerve?
Superior Gluteal A positive Trendelenburg is relatively non-specific and may indicate:Pain (e.g. due to osteoahritis of the hip joint)Weak hip abductors (gluteus medius, gluteus minimus)Sho femoral neck/ fracture of neckDislocation or subluxation of the hipNeuropathyGluteus medius and minimus are supplied by Superior G...
3
Obturator
Sciatic
Superior Gluteal
Inferior Gluteal
Anatomy
null
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True about area specific Curette is
null
4
Used in specific areas
Curved in two planes
One cutting edge is used
All of the above
Dental
null
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multi
Nerve supply of opponens pollicis ?
Hand muscles supplied by median nerve are :- i) Thenar muscles (except adductor pollicis) :- Flexor pollicis brevis, opponens pollicis and abductor pollicis brevis. Adductor pollicis is supplied by ulnar nerve. ii) First two lumbricals. Hand muscles supplied by ulnar nerve are :? 1) Superficial terminal branch : It sup...
3
Superficial branch of ulnar nerve
Deep branch of ulnar nerve
Median nerve
Posterior interosseous nerve
Anatomy
null
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single
A patient presented with splenomegaly, anemia & shows reticulocytosis with increased bone marrow cellularity. The diagnosis is:
Hemolytic anemia - reticulocytosis with splenomegaly is seen. Skull and skeletal deformities can occur in childhood due to a marked increase in hematopoiesis and resultant bone marrow expansion
2
Pernicious anemia
Hemolytic anemia
Myelofibrosis
Hairy cell leukemia
Medicine
Thalassemia
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Laboratory test of ANUG is:
null
2
Complement fixation
Dark field examination
Tissue culture
Animal inoculation
Dental
null
fa303bdd-78b4-401c-bd0c-6eb5761b88fb
single
Which is pleuripotent stem cell ?
Answer- A. Embryonic stem cellStem cellsEmbryonic stem cells : These are pleuripotent cellsAdutt stem cells
1
Embryonic stem cell
Tissue stem cell
Adult stem cell
Hematopoietic stem cell
Pathology
null
5253206a-3350-434a-9d8d-182361ab086e
single
Which of the following statement is true regarding time of ovulation?
Ans. c. Occurs after follicular ripening by FSH (Ref: Williams Obstetrics 23/e p355-356: Ganong 22/e p438: Shaw's 13/e p212)Follicular phase is under control of FSH and LH. Both FSH and LH is responsible for follicular ripening, but a surge in LH secretion triggers ovulation.OvulationLH surge is primarily caused by 'po...
3
Occurs before LH surge
Occurs after biphasic rise in basal body temperature
Occurs after follicular ripening by FSH
Occurs after disappearance of cervical mucus thickening
Physiology
Sex Hormones
145c914b-4e49-46a7-950d-5b12e8beb4c6
multi
Not true regarding Choledochal cyst
Choledochal cyst Cystic dilation of the biliary ducts, more common in females Clinical features. Classical triad : Pain, jaundice (intermittent) & abdominal mass(10%). Most common symptom in infants : Jaundice (in 80%) Most common symptom in patients >2 years of age : Abdominal pain. In children, the major clinical sym...
4
Epigastric mass
Jaundice
Pain in abdomen
Cystojejunostomy is the treatment of choice
Anatomy
G.I.T
59afed95-2a68-4532-b556-679715e25a2c
multi
Maximum contribution to atomospheric air is-
Ans. is 'a' i.e., N2 * The constituents of air:-# Major - Nitrogen (N2) - 78.1 %, Oxygen (O2) - 20.93%, Carbon dioxide (CO2) - 0.03%# Minor - Argon, neon, krypton, xenon, helium, water vapour, traces fo ammonia, suspended matter (dust, bacteria, spores, vegetable debris).
1
N2
O2
CO2
Helium
Social & Preventive Medicine
Environment and Health
735f7a0f-5bef-4714-b9ee-e0849a025d03
single
Ring Enhancing lesion In AIDS patient is Most Likely due to?
*Toxoplasmosis and CNS lymphoma are the major differentials for a Ring Enhancing lesion in AIDS Patients Toxoplasmosis produces Eccentric target sign within a ring Enhancing lesion
4
Cryptococcosis
Hydatid Cyst
Neurocysticercosis
Toxoplasmosis
Radiology
Neuroradiology
5232a258-3e43-481c-b532-093247683875
single
Which group of drugs is most effective for the healing of Non steroidal Anti Inflammatory Drug (NSAID) induced gastric ulcer-
Ans. is 'c' i.e., Proton pump inhibitors o Drug of choice for NSAIDs induced peptic ulcer ---> PPIs o Most specific drug for NSAIDs induced peptic ulcer --> Prostaglandin analogue.
3
Prostaglandin analogues
H2-receptor antagonists
Proton pump inhibitors
Antacids
Pharmacology
null
eb379b18-9f1c-476e-8bf8-d7379165ce9d
single
Mature RBC contains all except -
Ans:B .) Enzymes of TCA cycle Erythrocytes (RBC) lack mitochondria (so TCA cycle enzymes) and completely rely on glucose as their metabolic fuel. They metabolize it by anaerobic glycolysis.
2
Enzyme of HMP shunt pathway
Enzyme of TCA cycle
Glycoytic enzymes
Pyridine nubleotides
Biochemistry
null
20d27f25-9a0e-45a3-90cb-770510dd8905
multi
A patient developed fixed drug eruptions after taking ceain medications. Which of the following drug will give rise to these skin lesions in this patient?
A fixed drug eruption (FDE) is an adverse cutaneous reaction to an ingested drug, characterized by the formation of a solitary (but at times multiple) erythematous patch or plaque. Most commonly implicated agents in fixed drug eruptions: Tetracyclines (tetracycline, minocycline) Sulfonamides, other sulfa drugs Metronid...
4
Phenolphthalein
Aspirin
Dapsone
All of the above
Skin
null
4ae73ffd-8a1a-4027-a0f2-53aedcc25fef
multi
A woman with amenorrhea is having negative progesterone challenge test but has bleeding on combined estrogen-Progesterone challenge. What can be the cause -
Ans. is 'd' i.e., Pituitary tumor Negative progesterone challenge test - which rules out PCOD - (otherwise too, PCOD is a cause of secondary amenorrhea).When next step was done i.e., estrogen, progesterone combined test - It comes out to be positive i.e., compament I system (uterus, endometrium and outflow tract) is no...
4
Anovulation
Asherman syndrome
Pregnancy
Pituitary tumor
Gynaecology & Obstetrics
null
62677977-9490-48c1-9bdf-53aeb9c29e52
multi
Multiple bih are commonest among .
Negroes
4
Indians
Mongol
Caucasians
Negroes
Gynaecology & Obstetrics
null
e502d008-2b2d-4d51-bf8d-16e223930803
single
Given immediately in hemorrhagic shock:
Ans. (c) CrystalloidsRef: Bailey & Love 26th ed. /16-17* Crystalloid is the first fluid of choice for resuscitation. Immediately administer 2 L of isotonic sodium chloride solution or lactated Ringer's solution in response to shock from blood loss. Fluid administration should continue until the patient's hemodynamics b...
3
Packed RBC
Colloids
Crystalloids
Isotonic fluids
Surgery
Shock
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multi
Structures passing through the sigmoid (mandibular) notch are:
The upper border of the ramus of mandible is thin, and is surmounted by two processes, the coronoid process anteriorly and the condyloid process posteriorly, separated by a deep concavity, the mandibular notch, or sigmoid notch. It allows the passage of the masseteric nerve (a branch of the mandibular nerve (V3) divisi...
3
Auriculotemporal nerve
Mandibular nerve
Masseteric nerve and vessels
Chorda tympani
Anatomy
null
56bae87c-e4fd-4917-836d-50c4efb72115
single
All are first rank symptoms of schizophrenia, except: TN 06; UPSC 08; Karnataka 11; NIMHANS 11; NEET 13; PGI 14
Ans. Perplexity
4
Audible thoughts
Thought broadcasting
Voice arguing or discussing or both
Perplexity
Forensic Medicine
null
a024155b-39c1-4ed3-bfb9-17f61086557d
multi
Intralobar sequestration of lung takes its blood supply from -
Ans. is 'b' i.e., Descending abdominal aorta o A sequestration consists of normally developed bronchioles and alveoli supplied by systemic rather than pulmonary arteries.o This blood supply is from the Aorta either above or below the diaphragm.o Mostly fapprox 95%) this is from the descending thoracic aorta.o Other cha...
2
Internal mammary artery'
Descending abdominal aorta
Pulmonary artery
None of the above
Surgery
Miscellaneous (Lung)
31e4b89a-2134-4643-ad21-2e35db11a5ff
multi
a 25 year old female presented to the hospital on 3rdday of menstruation with complaints of high fever vomiting and rash on her trunk and extremities. on investigations she had leukocytosis and negative blood culture. she is diagnosed as :
TOXIC SHOCK SYNDROME Toxic shock syndrome (TSS) is an acute, febrile illness produced by a bacterial exotoxin, with a fulminating downhill course involving dysfunction of multiple organ systems. It is not unusual for the syndrome to develop from a site of bacterial colonization rather than from an infection. A woman wi...
3
staphylococcal food poisoning
scalded skin syndrome
toxic shock syndrome
varicella zoster infection
Microbiology
All India exam
98c89f05-78e6-4707-9a87-5f58c9d5541d
single
In centrilobular (centriacinar) emphysema, there is an abnormal, permanent enlargement of the -
. Respiratory bronchioles
1
Respiratory bronchioles
Alveolar ducts
Small bronchi
Bronchioles
Pathology
null
0ce08041-75d4-4142-8ffd-479727108fb7
multi
Absent ankle jerk and extensor plantar response is found in -
null
1
Friedreich's ataxia
Tabes dorsalis
SACD
Vit B deficiency
Medicine
null
1349d9a4-85de-4a0b-9c22-fed2a40be6ee
single
Adrenaline is added to lignocaine to prolong its effect and decrease its absorption into blood stream in a ratio of :
null
3
1:50,000
1:100,000
1:200,000
1:500,000
Pharmacology
null
aaff3b32-064a-4b4b-a486-2c9f453524b5
single
The treatment for a child with cherubism is
null
2
surgical excision
cosmetic surgery after puberty
radiation
Enbloc dissection
Pathology
null
1396001d-1606-4185-9338-20aea9759565
single
Final common pathway of metabolism of carbohydrate, lipids and protein metabolism is?
ANSWER: (C) TCAREF: Lippincott's biochemistry 4th ed page 109, Harper's 28th ed page 306See Biochemistry 2013 Session 2 for details of TCA/kerb cycle cyde is an aerobic pathway, because O2. is required as the final electron acceptor. Most of the body's catabolic pathways converge on the TCA cyde. Reactions such as the ...
3
Glucogenesis
Gycolysis
TCA
HMP pathway
Biochemistry
Kerbs Cycle
aa1c6808-490b-4f14-bea3-166204b191a3
single
Stapes footplate covers :
Ans. is 'b' i.e. Oval window Oval window is present in the medial wall of the middle ear. It is covered by foot plate of stapes.The other window round window is also present on the medial wall. It is covered by secondary tympanic membrane.Role of these 2 windows in hearingOval window -It receives sound vibration and tr...
2
Round window.
Oval window.
Inferior sinus tympani.
Pyramid
ENT
Anatomy of Middle Ear (Otitis Media)
250b27e1-ef5c-4d9c-a2f5-941f667658d6
single
Newborn 7 days old with vomiting and dehydration clinical examination was normal except for hyperpigmentation of nipple. Electrolytes Na: 120 meq. K: 9 meq. most likely diagnosis -
Congenital adrenal hyperplasia due to a defect in CYP21A2 is suggested by episodes of acute adrenal insufficiency with hyponatremia, hyperkalemia, dehydration & vomiting
1
Cong, adrenal hyperplasia
Primary hypothyroidism
Panhypopituitarism
Pyloric stenosis
Medicine
null
6f42d1c8-efc6-4530-8639-a82d86abeee4
multi
Volume of air taken in and given out during normal respiration is referred to as:
B i.e. T V
2
IRV
TV
ERV
VC
Physiology
null
49287ccd-a21d-4b27-9998-0f6b82efd783
single
Which of following anti-gout drugs act by inhibiting the enzyme xanthine oxidase?
DRUGS USED IN CHRONIC GOUT Group Mechanism Drugs Uric acid synthesis inhibitors Xanthine oxidase inhibitors Allopurinol, Febuxostat Uricosuric agents URAT-1 transpoer inhibitors Probenecid, Sulfinpyrazone, Benzbromarone, Lesinurad Recombinant uricase Cause oxidation of urate to allantoin Rasburicase, Pegloticase
3
Probenecid
Rasburicase
Allopurinol
Sulfinpyrazone
Pharmacology
NSAIDs, Gout and Rheumatoid Ahritis
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multi
Salvizol is a root canal irrigants with composition:
SALVIZOL Salvizol is a detergent suggested for irrigating root canals during instrumentation. It is a root canal chelating irrigant, N1-decamethylene-bis-4-aminoquinaldinium-diacetate. Kaufman et al, has showe that salvizol, with a neutral pH level has a broad spectrum of bactericidal.
1
N1- decamethylene-bis-4aminoquinaldinium-dia-cerate.
bis-dequalinium acetate.
4-chlorophenyl rings.
None.
Dental
null
1538ad81-c5d6-44f8-8eae-8e7f79db9e1a
multi
All the following statements about leukotriene modifers in the management of bronchial asthma are true except
Leukotriene modifers ( monteleukast,zafirulukast) may be considrrco as alternatives to low dose inhaled coicosteroids in patients with mild persistent asthma . Has no role in treating acute severe asthma Ref Harrison 19th edition pg 1673
1
May be used for acute asthma
May be used for exercise induced asthma
Zileuton is leukotriene modifer
May uncover chrug Strauss syndrome
Anatomy
Respiratory system
ff19a991-e8b2-49be-aa7a-53a50259d184
multi
Which of the following passes through the foramen magnum?
Foramen magnum transmits Lower end of medulla Anterior spinal aery Posterior spinal aery 4th pa of veebral aery Spinal pa of XIth nerve Other structures: Apical ligament and tip of dens, membrana tectoria, veical band of Cruciate Ligament.
1
Veebral aery
XII cranial nerve
Cranial pa XIth nerve
Internal carotid aery
Anatomy
Cranial cavity
b72479e8-cef8-4efb-8110-f8e674fd0fe8
single
The most common cause of trismus is due to infection in muscle:
The most common cause of trismus is due to infection adjacent to muscles of jaw closure i.e., masseter, medial pterygoid, temporalis mostly due to involvement of pericoronal, submasseteric, and pterygo mandibular spaces.
2
Masseter
Medial pterygoid
Temporalis
All of the above
Surgery
null
6adc7aa4-93f0-4bf8-840e-c436dd9f6e38
multi
A soldier from Siachen came in emergency. How will you rule out hypothermia?
Ans. (B) Rectal temperature style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">(Ref: ?)Preferred is two sites temperature check--rectal and esophageal.In the given clinical scenario rectal temperature would be preferred site to measure the core body temperature.During the low or high temp...
2
Oral temperature
Rectal temperature
Nasal temperature
Infrared tympanic probe
Medicine
Infection
c9e64b59-0bbc-4586-9f2b-af26f288072a
single
Intestinal angina is a symptom complex of the following-
null
2
Postprandial abdominal pain, weight loss, acute mesenteric vessel occlusion
Postprandial abdominal pain, weight loss, chronic mesenteric vessel occlusion
Preprandial abdominal pain, weight loss, chronic mesenteric vessel occlusion
Preprandial abdominal pain, weight gain acute mesenteric vessel occlusion
Medicine
null
1ac8c6a9-6ddd-4894-b751-7cd884f1007c
single
Which of these doesn't present with granulomatous Vasculitis?
Ans. (d) Microscopic polyangitisRef: Harrison 19th ed. / 2186* MPA is characterized by pauci-immune, necrotizing, small vessel vasculitis without clinical or pathological evidence of granulomatous inflammation* The family of vasculitic granulomatoses comprise# Wegener s granulomatosis# Necrotising sarcoidal granulomato...
4
Polyarteritis nodosa
Wegeners
Churg strauss syndrome
Microscopic polyangitis
Medicine
Immunology and Rheumatology
46b5220e-c194-4d2d-85ac-edf334c286a1
single
The drug possessing antagonistic action at histamine, serotonin and muscarinic receptors is :
null
3
Promethazine
Terfenadine
Cyproheptadine
Hydroxyzine
Pharmacology
null
e3aa9a46-6044-4638-9cf9-b1c3692f895c
single
Following can be used in the treatment of myoclonic seizures except –
Drugs used in myoclonic epilepsy Valproate (DOC)                           Lamotrigine         Topiramate      Clonazepam   Felbamate   Zonisamide
2
Valporate
Carbamazepine
Topiramate
Zonisamide
Pediatrics
null
6cdded3b-3a13-458c-bcbc-bb158541a1f2
multi
Which histopathological type of odontogenic keratocyst is commoner, more invasive & has a greater tendency for recurrence?
null
2
Orthokeratinised
Parakeratinised
Non-keratinised
Diskeratinised
Pathology
null
01b12082-4c81-4de7-bc29-8e270ffd8339
single
Mushroom cap sign in MRI is seen in:-
Rectosigmoid endometriosis: - The endometrial deposit on rectum causes proliferation of muscularis propria and the surrounding tissues which is seen as "mushroom cap sign" in T2 weighted MRI.
4
IIeocaecal TB
Pulmonary endometriosis
Ovarian endometriosis
Rectal endometriosis
Radiology
Women Imaging
f2e310b1-00ed-42bc-a457-d35731e94aad
single
Left axis deviation is seen in which of the following cyanotic congenital heart disease
Left axis deviation  seen in tricuspid atresia (TA), since it is the  only cyanotic congenital heart disease with Left ventricle dominance
3
TAPVC
TGA
TA
TOF
Medicine
null
7c152931-ecc4-4619-b471-478c922dae45
single
A patient presents with fever. Peripheral smears shows band across the erythrocytes. Diagnosis is ?
Ans. is 'd' i.e., P malariae Band across erythrocytes (band-form trophozoites) is characteristic of P malariae.
4
P Falciparum
P vivax
P ovate
P malariae
Microbiology
null
d15156dd-6810-4cbc-a473-b4825f37f41a
single
Which of the following statements about 'Late Expanding Phase of Demographic Cycle' is TRUE?
In late expanding phase of demographic cycle death rates declines faster than the bih rate and there is a steady decrease in the demographic gap. In this state population grow at a steadily decreasing rate. Most of the developing countries are now at early expanding and late expanding stages of demographic cycle. Ref: ...
3
Bih Rate is lower than Death Rate
High Death Rate and High Bih Rate
Death Rate declines more than Bih Rate
Death Rate begins to decline while Bih Rate remains unchanged
Social & Preventive Medicine
null
e338a46c-10d4-4a71-85de-bb3e9ad66237
multi
Which among the following is NOT a feature of Consolidation?
ANSWER: (D) Trachea shifted to side of consolidationREF: Oxford Handbook of Clinical Examination and Practical Skills by James Thomas, TanyaMonaghan Page 212"Trachea is in midline in consolidation because consolidation does not change the mediastinalposition"SIGNS OF CONSOLIDATION:Increased vocal fremitusDullness on pe...
4
Increased Vocal fremitus
Dull note on percussion
Bronchial breath sounds
Trachea shifted to side of consolidation
Medicine
Pneumonia, Bronchiectasis, and Lung Abscess
04824ae9-dc1d-4b93-9e79-93394865ada5
single
A drug that is NOT contraindicated in G–6 PD deficiency is :
null
4
Primaquine
Nitrofurantoin
Dapsone
INH
Pharmacology
null
6a4bf30a-5c3b-407e-a813-fa07e533e85a
single
Commonest salivary gland tumour in children -
Most common tumor of salivary gland in children - Hemangioma. Most common malignant tumor of salivary gland in children - Mucoepidermoid Carcinoma. After hemangioma, pleomorphic adenoma is the most Common salivary gland neoplasm.
4
Lymphoma
Adenoid cystic Ca
Pleomorphic adenoma
Mucoepidermoid Ca.
Pathology
null
c5196421-d1f9-4cfc-95b0-1055be5dbeab
single
Best way to prevent hypotension during spinal anesthesia
A i.e. Preloading with crystalloids
1
Preloading with crystalloids
Mephentermine
Dopamine
Tredelenbug's position
Anaesthesia
null
c1fb2fc0-8c36-43b8-ae66-fb37eeba2623
multi
All ofthe following are associated with normal pressure spontaneous CSF leaks, Except -
null
1
Pseudo tumor Cerebri
Empty Sella Syndrome
Encephalocele
Meningiocele
Medicine
null
1060b908-721a-4f0a-ae58-8b37e61b3092
multi
Following pattern in DNA electrophoresis is seen in
.
1
Apoptosis
Necrosis
Dyplasia
Metaplasia
Anatomy
All India exam
5044b7a0-0fae-41cf-b43b-db46e5d18274
single