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Which of the following toxin acts by inhibiting protein synthesis?
Shiga toxin also known as verotoxin, was first identified in a major cause of dysentry called Shigella dysentriae. Shiga toxin contains an enzymatic domain and 5 binding domains which bind to globotriaosylceramide (Gb3), a glycosphingolipid on the surface of cells and the complex is internalized. The internalized shiga...
4
Cholera toxin
LT of enterotoxigenic E.coli
Peusis toxin
Shiga toxin
Microbiology
null
46a7c121-014d-4cb4-a1a2-fa21ce769d66
single
The phenomenon of cancer cells switching to glycolysis even in the presence of adequate oxygen for oxidative phosphorylation is known as:
Even in the presence of ample oxygen, cancer cells shift their glucose metabolism away from the oxygen hungry, but efficient, mitochondria to glycolysis. This phenomenon, called the Warburg effect and also known as aerobic glycolysis, has been recognized for many years (indeed, Otto Warburg received the Nobel Prize for...
2
Tyndall effect
Warburg effect
Hawthorne effect
None of the above
Biochemistry
null
4cdd7184-db93-47f4-9812-fbe08c253c7f
multi
All of the following structures are present deep to Pterion except
Structures present deep to Pterion areMiddle meningeal vein and aeryStem of lateral sulcus of brain Reference: Chourasia; 6th edition; 12th page
4
Middle meningeal vein
Anterior division of middle meningeal aery
Syln Point
Temporal branch of Facial nerve
Anatomy
Head and neck
c01505e1-0d53-461a-a3c2-ab24d388ee13
multi
The appropriate size of LMA for an average adult patient weighing 50 kg is:
Ans. c. 4.0
3
2.5
3
4
5
Anaesthesia
null
f673861f-998a-4808-963e-68f8f5b43324
single
Incidence of scar rupture in a pregnant lady with previous LSCS is :
0.20%
1
0.20%
0.50%
0.70%
0.90%
Gynaecology & Obstetrics
null
eb967938-a6ea-4906-b74e-d10e0b08b89e
single
Capsicum seed can be confused with: NEET 14
Ans. Dhatura
2
Strychnine
Dhatura
Ricinus
Opium
Forensic Medicine
null
d2fd8dcc-ada9-4d6a-8dcb-27ed85a307e6
single
"Groundglass hepatocytes" are seen in which of the following viral hepatitis?
Ans. b (Hepatitis B) (Ref Robbins 7th/899; TABLE 18-7)Robbins 7th/B99HBV HISTOLOGY# HBV infected hepatocytes may exhibit a cytoplasm packed with spheres and tubules of HBsAg, producing a finely granular eosinophilic cytoplasm (GROUNDGLASS HEPATOCYTES).Key Morphologic Features of Viral HepatitisAcute Hepatitis (Enlarged...
2
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Pathology
Liver & Biliary Tract
7ec255e8-b782-4207-b83b-73f5412c309f
single
Tumour arising from Rathke's pouch is
Rathke's pouch develop at the roof of oral cavity from surface ectoderm to form most of pituitary . Posterior pituitary develops from diencephalon. Craniopharyngioma is a tumor that develop in the sella turcica.
3
Meningioma
Glioma
Craniopharyngioma
Ependymoma
Anatomy
FMGE 2017
7d86d506-ac4d-4d4d-8019-f3ca69582d42
single
All are presentation of retinoblastoma except:
C i.e. Cataract
3
Leucocoria
Squint
Cataract
Glaucoma
Ophthalmology
null
7ee022cb-7a63-40d3-8c3d-32402187137a
multi
During Hysterectomy, Ureter is liable for injury at?
Where it crosses uterine aery REF: Novak's Gynecology chapter 5, chapter 22 "About 75% of all iatrogenic injuries to the ureter result from gynecologic procedures, most commonly abdominal hysterectomy" "Significant aerial bleeding during hysterectomy usually arises from the uterine aeries or the ovarian vessels near th...
3
Where it crosses pelvic brim
Where it enters bladder wall.
Where it crosses uterine aery.
None
Gynaecology & Obstetrics
null
21d57ed2-7db5-41ad-9507-02c1b5f733ea
multi
Intravenous resuscitation is required in a patient with 30% burns. Which of the following will be the best choice of fluid in the first 24 hours?
Most commonly used fluid for resuscitation in burns is ringer lactate. Some centres use human albumin solution or fresh-frozen plasma, and some centres use hypeonic saline. Intravenous resuscitation is indicated for children with a burn greater than 10% TBSA and adults with 15% TBSA. Parkland formula is the most widely...
3
Normal saline
Dextrose 5%
Ringer lactate
Whole blood
Surgery
null
9efaf1cd-69c3-4d88-8809-de119893c58f
single
Which of the following criteria can be used to determine if a pheochromocytoma lesion is benign or malignant
Ref Robbins 8/e p1159-1161;9/e p1135 Pheochromocytoma and their related counterpas in extra adrenal sites called paraganglioma, are notorious Because the only reliable indicator of metastasis potential is the presence of distant metastasis . Very malignant appearing tumors may not metastasize and benign appearing tumor...
2
Blood vessel invasion
Cannot be determined by microscopic examination
Hemorrhagic and necrosis
Nuclear pleomorphism
Anatomy
General anatomy
d9d51e30-8b31-4138-97ad-73fa46c9199d
single
Non cicatrical alopecia is present in-
C. i.e. Psoriasis
3
Scleroderma
Lichen planus
Psoriasis
Parva virus
Skin
null
5cafd85f-ca1e-43ca-84af-cc03d478e531
single
Time dependent Killing is exhibited by all the following drugs except:
* Time dependent killing(TDK) : Here, the killing activity depends upon the length of time, plasma concentration is above MIC. It is shown by:* Beta Lactams.* Vancomycin Concentration dependent killing(CDK) : Here, killing activity depends upon the ratio of plasma concentration to MIC.It is shown by:* Aminoglycosides.*...
3
Ceftriaxone
Vancomycin
Gentamicin
Meropenem
Pharmacology
Protein Synthesis Inhibitors
857f0b90-de63-4fbb-8864-94dea9de31bd
multi
Prozone phenomenon is due to-
Ans. is 'b' i.e., Excess antibody
2
Excess antigen
Excess antibody
Hyperimmune reaction
all
Microbiology
null
554361c6-a037-426a-a530-136b0009f1c0
multi
Cart wheel appearance of Tympanic membrane is seen in which stage of Asom
null
4
Stage of Tubal occlusion
Stage of Resolution
Stage of suppuration
Stage of Pre-suppuration
ENT
null
39534c0b-dc03-4b23-a7e3-f3f5a1695fa8
single
Rocky mountain spotted fever Cause and vector are:-
RICKETTSIAL DISEASE CAUSE VECTOR RESERVOIR EPIDEMIC TYPHUS R. prowazekii Louse Man ENDEMIC TYPHUS R. typhi Flea Rodents SCRUB TYPHUS R. tsutsugamushi Trombiculid mite Rodents INDIAN TICK TYPHUS R. conori Tick Rodents RMSF R. ricketisii Tick Rodents R.POX R. akari Mite Rodents Q FEVER Coxiella - Cattle TRENCH FEVER Baon...
3
R. Akari and mite
R. Conori and tick
R. Rickettsii and tick
R. Prowazekii and louse
Social & Preventive Medicine
VBDs, Arboviral & Viral Infections, Surface Infections
31ddf634-052d-4e46-adff-ea8cc2ff6068
single
Fluid content of the blood is:
null
1
Plasma
Serum
Water
Tissue fluid
Physiology
null
683d22b2-7075-4df3-afe4-47f5f3dc1bfa
single
Emergency contraceptives are effective if administered within following period after unprotected intercourse:
Ans. is d, i.e. 120 hoursRef: Shaw 15th/ed, p237; Current Concepts in Contraception and Women Death, pl05, Leon Speroff8th/ed, p1042The standard recommendation is to start emergency contraceptive not later than 72 hours. The greatest protection is offered, if it is taken within 12 hours, as postponing the dose by 12 ho...
4
24 hours
48 hours
72 hours
120 hours
Gynaecology & Obstetrics
Contraceptives
42d6d9d0-8c2d-4d9d-8883-f85610e59c3f
single
All of the following are true regarding Temporal arteritis except
(B) Unilateral headache # Giant cell arteritis or Cranial arteritis or Temporal arteritis> Occurs almost exclusively in individuals > 50 years> The disease is characterized by the complex of fever, anemia, high ESR, and headaches in a patient over the age of 50 years.> A well recognized & dreaded complication of giant ...
2
Age > 50 years
Unilateral headache
Diagnosed by measuring high ESR
Complicated by ischemic optic neuropathy
Medicine
Miscellaneous
ea09d8bf-a5f0-4bbe-b32d-fbf0df74056a
multi
Adequate Total per capita water for Urban domestic purposes?
Ans. is 'c' i.e., 150-200 litresThe basic physiological requirements for drinking water have been estimated at about 2 litres per head per day.A daily supply of 150-200 litres per capita is considered as an adequate supply to meet the needs for all urban domestic purposes.
3
50-100 Liters
100-150 Liters
150-200 Liters
200-250 Liters
Social & Preventive Medicine
null
1d306e41-d04e-45fd-b435-41f6c07fdda1
single
An autoimmune disease is – a) Pemphigus vulgarisb) Psoriasisc) Lichen planusd) Acne vulgaris
Autoimmune skin disorders Autoimmune bullous skin disorders Pemphigus Bullous pemphigoid Dermatitis herpetiformis Lichen planus Lichen planus is believed to be an autoimmune disorder as it often occurs concurrently with other autoimmune disorders like primary biliary cirrhosis, diabetes, chronic active hepatitis. ...
1
abc
bc
acd
bcd
Dental
null
47c1fa8d-0ab7-41db-9250-a26de1e35027
single
Aerial blood supply to Little's area is from all the following except
Aeries supplying Little's area are: a. Sphenopalatine aery. b. Superior labial aery. c. Anterior ethmoidal aery. d. Septal branches of greater palatine aery.
4
Sphenopalatine aery
Anterior ethmoidal aery
Superior labial aery
Posterior ethmoidal aery
Pathology
All India exam
d7efce9a-b450-4047-b4ec-6302066554f5
multi
Ligamentum teres is the remnant of
(A) Umbilical vein SOME FREQUENTLY ASKED REMNANTS* Ductus arteriosusLigamentum arteriosum* Ductus venosusLigamentum venosum* Left umbilical veinLigamentum teres of liver* Right umbilical veinDisappears* Vitello-intestinal ductMeckel's diverticulum* Wolffian ductGartner duct> After obliteration, the umbilical vein forms...
1
Umbilical vein
Portal vein
Ductus venosus
Umbilical artery
Anatomy
Misc.
a677f0a3-b6b2-42d3-908b-0c1d30c5e1ae
single
Classification of aoic dissection depends upon
Aoic dissection occurs when blood splays apa the laminarplanes of the media to form a blood-filled channel within theaoic wall.The clinical manifestations of dissection depend primarily on the poion of the aoa affected; the most serious complicationsoccur with dissections involving the proximalaoa and arch.Thus, aoic d...
2
Cause of dissection
Level of aoa affected
Percentage of aoa affected
None
Pathology
Cardiovascular system
8f914948-2833-44af-83b9-5356dc33fc16
multi
True about helicobacter pylori are all except -
null
4
Urea breath test is diagnostic
Grain negative, flagellate bacilli
Risk factor for development of adenocarcinoma of stomach
It provides life long immunity
Microbiology
null
05c02e5d-2b0f-47c1-9b0f-ae85c38ee50c
multi
All are indications for penile angiography except:
Priapism is of two types. A low-flow (ischemic), painful priapism and the other high-flow (non-ischemic), painless priapism. Penile angiography is not indicated in the painful, low-flow priapism. It is indicated for the high-flow, non-ischemic priapism which is painless. Priapism Priapism is defined as prolonged erec...
1
Painful priapism
Peyronie's disease
Erectile dysfunction
Arterio-venous malformation
Surgery
null
86f41989-84fe-4af8-a337-ffb783d44834
multi
Most impoant enzyme in DNA replication for chain elongation
Ans. is 'c' i.e.,DNA polymerase III Impoant DNA PolymerasesIn ProkaryotesDNA polymerase I :- Helps in gap filling and synthesis between okazaki fragments of lagging strand, and replaces ribonucleotides of RNA primer by deoxyribonucleotides. It has (i) 3' 5' exonuclease activity, (ii) 5' 3' exonuclease activity and (iii...
3
Helicase
DNA polymerase I
DNA polymerase III
Topoisomerase III
Biochemistry
null
1b987a0b-2fbc-407c-8ade-b8d813117243
single
Which of the following is the least common site of pain in a case of rheumatoid ahritis? NOT RELATED- OHO
.
3
Cervical
Knee
Low back
Ankle
Pharmacology
All India exam
92635d7a-5567-4d5c-8a4b-d1825418e6bc
single
Superficial perineal muscles include-
Muscles in superficial perineal space. -        Ischiocavernosus -        Bulbospongiosus -        Superficial transverse perinei
3
Iliococcygeus
Ischiococcygeus
Bulbospongiosus
Levator ani
Anatomy
null
62eb1fa4-d1dd-438e-aeab-b95f9053c535
single
Which anaesthetic modality is to be avoided in sickle cell disease –
null
3
General anaesthesia
Brachial plexus block
I.V. Regional Anaesthesia
Spinal
Anaesthesia
null
48f58d58-7c38-4402-a2f8-432e588223f1
single
Commonest cause of ureteric injury during surgical operation is
Surgical trauma during pelvic surgery is the most common cause of ureteric trauma This occurs most often during vaginal or abdominal hysterectomy when the ureter is mistakenly divided, ligated, crushed or excised. Pre-emptive ureteric catheterisation makes it easier to identify the ureters. ( ref : Bailey 27th ed , cha...
2
Abdomino-perineal resection
Hysterectomy
Prostectomy
Colectomy
Surgery
Urology
0f9b3bd0-1cde-4f9f-ae25-453760fa3465
single
Misoprostol is an analogue of
Misoprostal: PGE-1 Given transvaginally and orally Dose of 25 micrograms every 4 hrs is found to be more effective than PGE -2 for cervical ripening and labor induction. Oral use of misoprostal is less effective than vaginal administration . Ref: Dutta Obs 9e pg 485.
1
PGE1
PGE2
PGF2alfa
PGI2
Gynaecology & Obstetrics
Abnormal labor
f55764f6-a1de-404f-8fc2-296b52fdc15f
single
The thickness of thin rubber dam is:
null
3
0.002 inch
0.004 inch
0.006 inch
0.2 inch
Dental
null
28c2d5a3-6cdc-4666-af70-740e64b800a6
single
Which of the following is true about seminoma?a) It is radiosensitiveb) It arises only from cryptorchid testisc) AFP is increasedd) It is chemosensitive
Seminomas are both radiosensitive & chemosensitive tumors.
3
b
c
ad
ab
Surgery
null
b153349f-0c0c-4cae-863a-33177eb4abdb
multi
Radical dissection of neck includes all except -
null
3
Cervical lymph nodes
Sternocleido mastoid
Phrenic nerves
Internal jugular vein
Surgery
null
737a208e-0830-46e3-9056-2917b1108b2e
multi
Not a feature of traumatic optic neuropathy:
Macular edema is not a characteristic feature of traumatic optic neurpathy. Traumatic Optic Neuropathy Loss of vision. Dilatation of pupil. Impaired Pupillary light reflex. Contrast sensitivity is decreased. Central or centrocecal scotoma (though less common, it can be seen in traumatic optic neuropathy) MRI is the inv...
4
RAPD
Dilatation of pupil
Centrocecal scotoma
Macular edema
Ophthalmology
Retina
58e1a7dd-6fc3-4b0c-8195-c67ad3d198d3
single
Codex alimentarius is related to -
Food standards are done by CODE ALIMENTARIUS, PFA STANDARDS, THE AGMARK STANDARDS, BUREAU OF INDIA STANDARDS. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 610)
4
Water purity
Milk purity
Air polution
Food stardardization
Social & Preventive Medicine
Nutrition and health
023569d6-3a3d-41b5-8adb-8e560805adb3
single
Sinus not present at birth is -
Development and grwoth of paransal sinuses
4
Ethmoid
Maxillary
Sphenoid
Frontal
ENT
null
52fbc1c4-deb2-48c4-a05f-29dfd62e1ca8
single
Tillaux fracture involves:
Tillaux fracture Lower tibial epiphysis injury (anterolateral pa)
1
Lower end tibia
Upper end tibia
Lower end femur
Upper end femur
Orthopaedics
Lower Limb Traumatology
5c17bf5c-dddd-4581-b557-07251975b6fd
single
EEG rhythm in full awake and ale state?
Ans. is 'b' i.e., BetaBeta wave is seen when the person is fully awake and ale and is thinking with maximum concentration.Therefore it is also called arousal or ale response.
2
Alpha
Beta
Theta
Delta
Physiology
null
90252609-b0bf-4455-9576-b318fe579e69
single
Atractiloside act as ?
Ans. is 'b' i.e., Inhibitor of oxidative phosphorylationInhibitors of electron transpo chain?Inhibitors of respiratory chain may be divided into three groups : ?1. Inhibitors of electron transpo chain properThese inhibitors inhibit the flow of electrons through the respiratory chain. This occurs at following sites.Comp...
2
Uncoupler
Inhibitor of oxidative phosphorylation
Inhibitor of complex I of ETC
Inhibitor of complex III of ETC
Biochemistry
null
538885ec-99dd-4e01-8c61-7416435ea194
single
Champagne glass pelvis is seen in
(Achandroplasia): (306- Maheshwari 4th edition)Champagne - glass' pelvic cavity found in ACHONDROPLASIA(275-Aids to radiological differential diagnosis chapman)ACHONDROPLASIA(Primary defect of enchondral bone formation, Autosomal dominant (but 80% are spontaneous mutations)SkullPelvis1. Large skull, small base, small s...
2
Cretinism
Achandro plasia
Osteomalacia
Rickets
Orthopaedics
Miscellaneous
e5554a36-2285-40cc-8020-554dda2f3b20
single
Type A (augmented) adverse drug reactions are characterized by all EXCEPT:
Predictable (Type A or Augmented) reactions - quantitatively responses- includes side effects, toxic effects and consequences of drug withdrawal. They are more common, dose-dependent and mostly preventable and reversible. Ref ; KD Tripathi pharmacology 7 th edition (page no; 82)
1
Qualitatively abnormal responses to the drug
Predictable from the drug's known pharmacological or toxicological effects
Generally dose-dependent
Usually common
Pharmacology
General pharmacology
88fabb45-2feb-447b-8ede-75d43494046a
multi
A specimen from a lung biopsy reveals occasional plexiform lesions within pulmonary aerioles. This abnormality is most characteristic of
) Pulmonary vascular sclerosis refers to the vascular changes associated with pulmonary hypeension. Elevation of the mean pulmonary aerial pressure is the result of endothelial dysfunction and vascular changes. The vascular changes vary with the size of the vessel. The main aeries have atheromas that are similar to sys...
4
Churg-Strauss syndrome
Adult respiratory distress syndrome
Wegener's granulomatosis
Pulmonary hypeension
Pathology
miscellaneous
a7e9ea72-b4ac-4121-b916-f7e54de42f75
single
Incised looking laceration is seen in all, except AFMC 11; NEET 13
Ans. Chest
4
Iliac crest
Zygomatic bone
Shin
Chest
Forensic Medicine
null
92670377-2898-492a-bd74-8c5f2190e230
multi
Large placenta is seen in
Ans. a Twins. (Ref. Dutta, Obstetrics, 4th/pg.221)D/d of Large placenta/hyperplacentosis:# Twin pregnancy# Hydrops fetalis# Diabetes in pregnancy# IUGRHUMAN PLACENTA# It is Discoid, Deciduate and Haemchorial.# It develops from--- foetal (4/5th)--chorionic frondosum and- maternal (l/5th)--decidua basalis.# Its developme...
1
Twins
Oligohydramnios
IUGR
Pre-eclamptic toxemia
Gynaecology & Obstetrics
Miscellaneous (Gynae)
4c49f1f9-24e6-4c2d-93e4-31aa596557f2
single
Socially acquired behavior is known as: March 2005, September 2010
Ans. A: Culture Culture is defined as "learned behaviour which has been socially acquired". It is the central concept around which cultural anthropology has grown. Socialization refers to the process of inheriting norms, customs and ideologies. It may provide the individual with the skills and habits necessary for paic...
1
Culture
Socialization
Internalization
Custom
Social & Preventive Medicine
null
d361ab60-b65c-4ff9-8e58-8a85362a2ebb
multi
Glucose diffusion in RBC by ?
Ans. is 'a' i.e., GLUT 1
1
GLUT I
GLUT 2
GLUT 3
GLUT 4
Physiology
null
a2b33a49-6906-457c-9330-9926e1e5a569
single
A 58 year old woman has been diagnosed with locally advanced breast cancer and has been recommended for chemotherapy. She has five years history of myocardial infarction and congestive heart failure. Which antineoplastic drug should be best avoided?
Ans. is 'a' i.e. AnthracyclineRef: Katzung 8th/e 937-938, Harrison 16th/e p 475 (15th/e p 434)Anthracyclines are anticancer antibiotics and they include Doxorubicin (Adriamycin) and Daunorubicin.The major toxicity of anthracyclines is potentially irreversible cumulative dose related toxicity.They may causes arrhythmias...
1
Anthracycline
Alkylating agent
Platinum compound
Bisphosphonates
Pharmacology
Anti-Neoplastic Agents
9815af73-704e-4c5c-a1a9-37e8ed16084c
multi
A 9-year-old girl child developed a 10 mm area of induration on the left forearm 72 hours after intradermal injection of 0.1 ml of purified protein derivative (PPD). Which of the following is most likely to be seen on the X-ray of this patient?
Most Mycobacterium tuberculosis infections are asymptomatic and subclinical infections. In most healthy people primary tuberculosis is asymptomatic, although it may cause fever and pleural effusion. Generally, the only evidence of infection, if any remains, is a tiny, fibrocalcific pulmonary nodule at the site of the i...
3
Marked hilar adenopathy
Upper lobe calcifications
No abnormal findings
Reticulo-nodular densities
Pathology
Pulmonary Tuberculosis and Lung Abscess
dd42d061-4d03-4c68-8f0d-8f384209bb95
single
All are seen in hypersplenism except:
Ans. (d) Hypocellular bone marrowRef: Sabiston 19/e p 1553-1554Hypersplenism:* Spleen Enlargement+Decrease in Cell count in more than one cell line (Anemia, thrombocytopenia, leucopenia) is known as hyper splenism* Important feature on Bone marrow study is there will be Hyper plasia and immediate improvement of blood c...
4
Anemia
Thrombocytopenia
Splenomegaly
Hypocellular bone marrow
Surgery
Spleen
fa0aad7f-16a8-4459-a7e0-1e451da8c5e3
multi
False regarding invlovement in Crohn's disease
Ans. is 'b' i.e., Rectum
2
Anorectal area
Rectum
Small intestine with Rt. colon
Large intestine alone without involvement of small intestine
Surgery
null
a6fc3739-fdca-4018-aa63-9d66ed22db10
multi
Latanoprost (PGF2 alfa) is used in -
Ans. is 'd' i.e., Glaucoma PG F2 alpha (Latanoprost) is used in glaucoma.
4
Maintenance of ductus aeriosus
Pulmonary hypeension
Gastric mucosal protection
Glaucoma
Pharmacology
null
2018386e-1a58-495e-927f-43c2de258008
single
The standard sutureless cataract surgery is done with phacoemulsification and foldable IOL has an incision of –
In phacoemulsification, the nucleus is emulsified using high frequency sound waves and then sucked out of the eye through a small (3.2 mm) incision.
3
1mm–1.5mm
2mm–2.5min
3mm–3.5mm
3.5mm–4.5mm
Ophthalmology
null
be5797c0-922f-4b84-809b-a178e4a8f0aa
single
Following sign is diagnostic of which condition?
Ans. C. Carcinoma stomacha. Ulcerating carcinoma of the stomach with mass is the most frequent type encountered in North America and Western Europe.b. These carcinomas have been described as irregular, saucer-shaped lesions with ulcerated centers.c. Such a configuration may produce the meniscus or Carman sign, which in...
3
Peptic ulcer disease
Strawberry gallbladder
Carcinoma stomach
Patent vitellointestinal duct
Radiology
G.I.T.
a102e59e-6ab6-4620-8193-42395f3928f3
multi
Glaukomflecken is –
Epithelial cell necrosis leads to focal opacification of the lens epithelium as glaucomflecken in acute angle-closure glaucoma.
2
Acute uvetis due to glaucoma
Lens opacity due to glaucoma
Retinal detachment due to glaucoma
Corneal opacity due to glaucoma
Ophthalmology
null
466a6eec-9817-4c9d-9492-243d9895e9ad
single
Elimination after 4 half lives in first order Kinetics is
Ans. is 'b' i.e., 93% Half life Elimination 1t%2 50% 2t'/2 75% 3 0/2 87.5% 41 93.75% 5 t'/ 96.875
2
84%
93%
80.50%
4.75%
Pharmacology
null
5b06347e-0194-4f80-9b78-9aa2c1ff7927
single
Hyperventilation in high altitude is due to
Hyperventilation in high altitude is due to respiratory alkalosis Ref: guyton and hall textbook of medical physiology 12 edition page number:375,376,377
1
Respiratory alkalosis
Respiratory acidosis
Hypercapnea
Decreased concentration of bicarbonate
Physiology
Respiratory system
6316b949-883e-429c-a197-f2dfffac989c
single
The following regarding colostomy are true except :
• Bailey says “Double-barrelled colostomy was designed so that it could be closed by crushing the intervening ‘spur’ using an enterotome or a stapling device. It is rarely used now, but occasionally the colon is divided so that both ends can be brought to the surface separately, ensuring that the distal segment is comp...
4
A colostomy is an artificial opening made in large Bowel to divert the faeces to the exterior
Temporary colostomy is established to defunction an anastomosi
Permanent colostomy is formed after the resection of Rectum by the abdominoperinea technique
Double barreled colostomy is commonly done nowadays
Surgery
null
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multi
The first step in public health procedure is-
* The steps in public health procedure are as follows- 1) Survey. 2) Situation analysis. 3) Programme planning. 4) Programme operation. 5) Financing. 6) Programme appraisal.
3
Analysis of programme
Planning of programme
Situation analysis
Appraisal of programme
Surgery
null
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multi
A young patient is diagnosed to have choriocarcinoma the treatment of choice is :
Chemotherapy
2
Hysterectomy
Chemotherapy
Chemotherapy followed by hysterectomy
Hysterectomy followed by chemotherapy
Gynaecology & Obstetrics
null
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In a family, the father has widely spaced eyes, increased facial hair and deafness. One of the three children has deafness with similar facial features. The mother is normal. Which one of the following is least likely pattern of inheritance in this case-
Ans. is 'a' i.e., Autosomal dominant (most likely) o It is typical presentation of waardeburg syndrome type - 1. --> Widely spaced eyes, Hearing loss, Increased facial hair o It is an autosomal dominant disorder. o In autosomal disorder, if one parent is affected and the other is normal, 25% of children (1 out of 4) wi...
1
Autosomal dominant
Autosomal recessive
X-linked dominant
X-linked recessive
Pediatrics
null
22f7e828-a48f-4e6a-a009-fe0e6a4057b7
single
Chvostek sign is?
1. Chvostek sign - seen in hypocalcemia - Twitching of Circumoral Muscle on tapping of Facial Nerve 2. Inability to open eye on tapping of facial nerve - L.P.S 3rd nerve
1
Twitching of circumoral muscles on tapping of facial nerve
Involuntary blink on tapping on facial nerve
Inability to open eye on tapping of facial nerve
Inability to close eye on tapping of facial nerve
Medicine
Electrolyte Imbalance
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Coho study is a type of -
Ans. is 'b' i.e., Analytic study Coho study o Coho study is a type of analytic observational study (like case control study). o Coho study proceeds forward from cause to effect, i.e., disease has not occured in subjects (In contrast to case-control study which proceeds backward from effect to cause).
2
Clinical trial
Analytic study
Descriptive study
Experimental study
Social & Preventive Medicine
null
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single
Lambda - Panda sign is typically seen in-
Ans. is 'a' i.e., Sarcoidosis o Lambda sign and Panda sign on Gallium scan are typically described for sarcoidosis.o Active pulmonary and/or mediastinal sarcoidosis is gallium avid and a positive gallium scan can support the diagnosis of sarcoidosis. Typical patterns of uptake have been described as 'panda' and 'lambda...
1
Sarcoidosis
Tuberculosis
Histoplasmosis
Leishmaniasis
Medicine
Interstitial Lung Disease
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multi
COWS is related to ?
Ans. is'b'i.e., Caloric testln bithermal caloric< test rCold water provokes nystagmus towards the opposite ear, while wann wotet grovolecs nystagmus towards sarne ear (COWS:- Cold - opposite, Warm - same).
2
Romberg test
Caloric test
Fistula test
Hallpike positional test
ENT
null
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multi
Pulmonary fibrosis is seen with :
Bleomycin is a marrow sparing drug but it causes pulmonary fibrosis and skin toxicity as adverse effects. Another antican­cer drug causing pulmonary fibrosis is busulfan.
1
Bleomycin
Cisplatin
Methotrexate
Actinomycin D
Pharmacology
null
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single
Phocomelia is-
Ans. is 'a' i.e., Absent long bones 'Phacomelia' o Is a term applied to a marked reduction in the size of limbs The distal pa of the limbs are placed very near the trunk (absent long bones). o Seen in foetuses of mothers who recieved thalidomide during pregnancy.
1
Absence of long bones
Absence of brain
Reduplication of bones
Absence of hea
Pediatrics
null
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Cutaneous vasoconstriction is mediated by
Sympathetic noradrenergic division constricts the blood vessels of the skin(which limits bleeding from wounds). Ref: Ganong&;s review of medical physiology; 23rd edition; pg: 268.
1
Sympathetic adrenergic nerves
Sympathetic cholinergic nerves
Parasympathetic cholinergics
Somatic nerves
Physiology
Nervous system
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Which is an indicator of severe Ulcerative colitis?
(A) Blood in lumen on sigmoidoscopy # Severe Ulcerative collitis: Bowel movements >6 per day, Severe Blood in stool, Severe Fever 37.5C mean.Tachycardia >90 mean pulse, Anemia <75%, Sedimentation rate >30 mm, Endoscopic appearance Spontaneous bleeding, ulcerations.> Sigmoidoscopy is used to assess disease activity and ...
1
Blood in lumen on sigmoidoscopy
Stool volume >1 It
Serum albumin <40
Abdominal discomfort
Medicine
Miscellaneous
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Dilator pupillae is supplied by -
Dilator pupillae muscle is suppliedby the postganglionic fibers arising from the cervical sympathetic chain. ... Oculomotor nerve supplies the skeletal as well as the smooth muscles of the eyeball. It carries the pre-ganglionic fibers from the Edinger-Westphal to supply two smooth muscles in the eyeball Ref AK khurana ...
2
Post-ganglionic parasympathetic fibers from Edinger Westphal nucleus
Post-ganglionic sympathetic fibers from cervical sympathetic chain
IIIrd nerve
Sympathetic fibers from fronto-orbital branch of V nerve
Ophthalmology
Ocular motility and squint
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Non-depolarizing blockade is potentiated by:
Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. This is accomplished either by acting presynaptically the inhibition of acetylcholine (ACh) synthesis or release or by acting postsynaptically at the acetylcholine receptors o...
4
Hyperkalemia
Hypomagnesemia
Chronic Phenytoin therapy
Quininidine
Pharmacology
Anesthesia
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Refrigerated blood stored up to 48 hours before transfusion can destroy which of the following
Treponema pallidum is killed in 1 to 3 days at 0-4degrees centigrade, so transfusion syphilis can be prevented by storing blood in the refrigerator before transfusion Stored frozen at -70deg C in 10% glycerol, or in liquid nitrogen (-130 deg C), it remains ble for 10-15 years. Ref: Textbook of microbiology; Ananthanara...
3
HIV
Hepatitis B
Treponema pallidum
Plasmodium vivax
Microbiology
Bacteriology
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A 30-yebar old patient presented with features of acute meningoencephalitis in the casualty. His CSF on wet mount microscopy revealed motile unicellular microorganisms. The most likely organism is -
Naegleria fowleri, the only pathogenic species of naegleria Human infection comes from water containing the amoebae and usually follows swimming or diving in ponds. Patients are mostly previously healthy young adults or children. The amoebae invade the nasal mucosa, pass through the olfactory nerve branches in the crib...
1
Naegleria fowleri
Acanthamoeba castellani
Entamoeba hystolytica
Trypanosoma cruzi
Microbiology
parasitology
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All of the following methods are used for the diagnosis of HIV infection in a 2 months old child, except:
HIV ELISA is required for detection of antibodies against the virus. The antibodies may be present in the infant because of maternal infection also because IgG antibodies can cross the placental barrier. So, this test is not reliable for diagnosis of HIV in a 2 month old child. HIV culture method is called as 'peripher...
3
HIV-1 PCR
Viral culture
HIV ELISA
p24 antigen assay
Pathology
Immunodeficiency Disorders
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Artery of hindgut is
null
3
Coeliac trunk
Superior mesenteric
Inferior mesenteric
None
Anatomy
null
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Usual sign of opioid withdrawal: PGI 13
Ans. Yawning
4
Stupor
Constipation
Constricted pupil
Yawning
Forensic Medicine
null
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Congenital toxoplasmosis, all are true, except
Congenital toxoplasmosis is a disease that occurs in fetuses infected with Toxoplasma gondii, a protozoan parasite, which is transmitted from mother to fetus.  It can cause miscarriage or stillbirth.  It can also cause serious and progressive visual, hearing, motor, cognitive, and other problems in a child.  Most infec...
4
Occurs in primarily infected mother during pregnancy
As gestational age increase, risk of transmission to fetus increases
Infant is usually asymptomatic, if infection is transmitted in 3rd trimester.
None of the above
Microbiology
null
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The reagent used in Apt test is
Alkali denaturation test (Apt-Downey test / apt test)Used to detect differentiate Fetal or neonatal blood from maternal blood (Qualitative).PrincipleMethodFetal hemoglobin (alpha 2 gamma 2 subunits) is resistant to alkali (basic) denaturation, whereas adult hemoglobin (alpha2 beta 2 subunits) is susceptible to such den...
3
Sodium bicarbonate
KCL
Sodium hydroxide
Sodium chloride
Pathology
All India exam
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Hanging drop method is used for-
null
1
Trichomonas
Plasmodium
Toxoplasma
Cryptosporidium
Microbiology
null
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single
Predict the effect of aldosterone hypersecretion on body fluid pH and electrolytes ?
Aldosterone increases the rate of sodium absorption and potassium secretion by the kidneys, but in high concentrations aldosterone also stimulates hydrogen ion secretion. Therefore elevated aldosterone levels such as occur in patients with Cushing's syndrome can elevate body fluid pH above normal (alkalosis). The major...
2
pH decreased, K+ decreased, Na+ increased
pH increased, K+ decreased, Na+ increased
pH decreased, K+ increased, Na+ decreased
pH increased, K+ increased, Na+ decreased
Physiology
null
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single
Isovolumetric relaxation preceeds:
Ventricular ejection
1
Ventricular ejection
Ventricular relaxation
Atrial contraction
Atrial relaxation
Physiology
null
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single
Saw tooth appearance in abdominal barium enema X ray is seen in
Diveicula These are abnormal outpouchings or sacs of colon wall that occur due to interactions of high intraluminal pressures, disordered motility and low diet in fiber Formed on mesenteric side of antimesenteric taenia coli Results in protrusion of mucosa and submucosa through layers of muscle It is Pseudodiveiculum o...
3
Multiple polyposis
Ischemic colitis
Diveiculosis
Ulcerative colitis
Surgery
GIT
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single
Receptor responsible for malignant hyperthermia is?
ANSWER: (B) Ryanodine receptorREF: Morgan 3ra e p. 869This condition is known by a number of names, including malignant hyperthermia (MH), malignant hyperthermia syndrome (MHS), and malignant hyperpyrexia.Signs and symptoms:The typical symptoms of malignant hyperthermia are due to a hyper catabolic state, which present...
2
Nicotinic receptor
Ryanodine receptor
Muscarinic receptor
None
Anaesthesia
Depolarising Neuromuscular Blocking Agents
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Hinge axis face bow records:
Kinematic facebow or Hinge axis facebow A facebow with adjustable caliper ends used to locate the transverse horizontal axis of the mandible (GPT8) It locates the true (exact) centre of condylar rotation or transverse horizontal axis. It is preferred in full mouth reconstructions. Hinge axis face-bow records—relations...
3
Relationship of the mandible to the maxilla
Relationship of the mandible to the cranium
Relationship of teeth to the axis of the relation of the jaw
All of the above
Dental
null
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multi
During a routine checkup, a 50-year-old man is found to have blood in his urine. He is otherwise in excellent health. An abdominal CT scan reveals a 2-cm right renal mass. You inform the patient that staging of this tumor is key to selecting treatment and evaluating prognosis. Which of the following is the most importa...
The choice of surgical approach or treatment modalities is influenced more by the stage of a cancer than by its cytologic grade. The significant criteria used for staging vary with different organs. Commonly used criteria include (1) tumor size, (2) extent of local growth, (3) presence of lymph node metastases, and (4)...
2
Histologic grade of the tumor
Metastases to regional lymph nodes
Proliferative capacity of the tumor cells
Somatic mutations in the p53 tumor suppressor gene
Pathology
Neoplasia
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single
Part of colon with no mesentery-
Ans. C. Ascending colona. The large intestine develops as a fully mesenteric organ. However, after the rotation of the gut tube in utero, large portions of it come to lie adherent to the retroperitoneum, which means that some parts of the colon are fixed within the retroperitoneum, and other parts are suspended by a me...
3
Transverse colon
Sigmoid colon
Ascending colon
Rectum
Anatomy
Large Intestine, Rectum, and Anal canal
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Among patients with polymyositis, which one of the following auto-antibodies is associated with an increased risk of interstitial lung disease?
Myositis Specific Antibodies Anti Jo-1 and anti synthetase antibodies Polymyositis and dermatomyositis with Interstitial lung disease, ahritis, mechanic's hands Anti-Mi-2 Dermatomyositis with rash Anti MDAS Dermatomyositis with rapidly progressive lung disease Anti-10 Juvenile dermatomyositis Anti-Signal recognition pa...
4
Anti-CCP antibody
Anti ds DNA antibody
Anti cardiolipin antibody
Anti-Jo-1 antibody
Medicine
Systemic Lupus Erythematous
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One gm of Hb liberates _______ mg of billurubin .
Approximately 35mg of bilirubin is formed from 1g of Hb. About 6g of Hb is broken down per day. A total of 300mg of bilirubin is formed everyday; of which 80% is from destruction of old RBCs, 10% from ineffective erythropoiesis and the rest 10% from degradation of myoglobin and other heme containing proteins. Reference...
2
40
34
15
55
Pediatrics
New born infants
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A 60-year-old man with no significant past medical history is scheduled for elective cholecystectomy. He has been taking aspirin daily. Preoperative recommendations should include which of the following?
Discontinuation of aspirin at least 1 week before surgery. Aspirin inactivates platelet cyclo-oxygenase and thus inhibits platelet aggregation. The effect of aspirin is irreversible and lasts for the entire life span of the platelets. Therefore, aspirin should be discontinued for at least 1 week before surgery.
4
Determination of prothrombin time (PT)
Estimation of platelet count
Discontinuation of aspirin 2 days before surgery
Discontinuation of aspirin at least 1 week before surgery
Surgery
Miscellaneous
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single
Missing cases are detected by?
ANSWER: (C) Sentinel surveillanceREF: Park 20th edition page 38The word surveillance is the French word for "watching over"Sentinel surveillance is useful for answering specific epidemiologic questions because sentinel sites may not represent the general population or the general incidence of disease, they may have lim...
3
Active surveillance
Passive surveillance
Sentinel surveillance
Monitoring
Social & Preventive Medicine
Concept of Control
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single
Malignant transformation is commonly seen in:
Ans. (b) Gastric ulcer* Malignant transformation is very rarely seen in gastric ulcer (<1%) - Not so common.* Giant gastric ulcer (>2cm) is associated with cancer in 6-15% cases* Of the above choices we can opt for choice B' only - but it is not so common.
2
Stomal ulcer
Gastric ulcer
Chronic duodenal ulcer
Postbulbar ulcer
Surgery
Stomach & Duodenum
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single
Eye lens dislocation seen in –a) Marfan\'s syndromeb) Homocystinuriac) Down\'s syndromed) Klinefelter syndrome
Marfan syndrome and homocystinuria can cause dislocation of lens.
3
ac
a
ab
bc
Ophthalmology
null
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'First order 'symptoms of schizophrenias' schizopremia include all except:
There are 11 first rank symptoms first three are related to thoughts - thought inseion , withdrawal & broadcasting next three are related to hallucinations -1St person ,2ND person & 3RD person next three are made phenomena remember MADE VOLITION, MADE IMPULSE, MADE AFFECT (mood) Last two are Somatic passivity & Delusio...
1
Depersonilization
Running commentary of ones thoughts
Primary delusion
Somatic passivity
Surgery
null
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multi
Micro nodular cirrhosis is commonly seen in all except,
Ans. is 'a' i.e., Chronic hepatitis B Cirrhosis of the liver is a pathological entity which clinically represents the end stage of chronic liver disease.It is characterized by three features.Bridging fibrous septa Q in the form of delicate bands or broad scars linking portal tracts with one another and portal tracts wi...
1
Chronic hepatitis B
Alcoholic liver disease
Hemochromatosis
Chronic extra hepatic biliary obstruction
Medicine
Cirrhosis and Alcoholic Liver Disease
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Most common cause of hypercalcemic crisis is :
A hypercalcaemiccrisisis an emergency situation with a severehypercalcaemia, generally above approximately 14 mg/dL (or 3.5 mmol/l)The most common cause is hypercalcemia of malignancy, although granulomatous diseases, previously undetected primary hyperparathyroidism, medication-induced hypercalcemia, and a few rarer c...
3
Parathyroid adenoma
Parathyroid hyperplasia
Malignancy
Paget's disease
Surgery
Parathyroid and adrenal glands
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Scarring loss of hair is seen in
Conditions causing scarring alopecia Causes of non-cicatricial alopecia (non-scarring) Traumatic causes of scarring alopecia may be due to: Injury Surgery Radiation Traction (tight curls) Central centrifugal cicatricial alopecia Infections causing scarring alopecia include: Bacterial infection: boils and abscesses (Sta...
1
Discoid lupus erythematosus
Atopic dermatitis
Alopecia areata
Systemic lupus erythematosus
Dental
Autoimmune skin disorders
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single
60 year old asymptomatic female shows following change in tunica media of blood vessels. Diagnosis?
Ans. (a) Medial calcificationMedial artery calcification (MAC) is also known as Monckeberg's arteriosclerosis, is a nonobstructive condition leading to reduced arterial compliance that is commonly considered as a nonsignificant finding.With the H&E stain, calcium appear deep blue-purple.
1
Medial calcification
Medial fibrosis
Amyloidosis
None
Pathology
Cellular Pathology
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The results of the pulmonary functions tests shown below, the best diagnosis is -ParametersActualPredictedFE VI (L)1[?]23[?]5-4[?]3FVC(L)4[?]14[?]6-5[?]4FEVL'FVC (%)2972-80PEF (L/min)80440-540DLCO120%100%
Ans. is 'a' i.e. Asthma o .All expiratory parameters are reduced in the data given with timed vital capacity of 29%.o FEV1/FVC is reduced in obstructive airway disease with lowering of peak expiratory flow rates. Due to air trapping in asthma the DLco may be normal or increased.
1
Asthma
Asbestosis
ARDS
Silicosis
Medicine
Asthma
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