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Which of the following statement is false about drugs used in rheumatoid ahritis? | Drug ending with inib - JAK inhibitor and given orally.- Tofacitinib- Beracitinib Drug ending with Mab: - Monoclonal antibody and IL-6 inhibitor.- Tocilizumab- SarilumabSix : IL-6A-AhritisR-RheumatoidI - InterleukinL - InterleukinUMAB: Monoclonal Antibody.All above mentioned drugs are used for Rheumatoid ahritis. Tocil... | 3 | Tofacitinib inhibits JAK1 and JAK3 | Tocilizumab inhibits IL-6 | Tofactinib is given intravenously | Tocilizumab is given by intravenous and subcutaneous route | Pharmacology | JIPMER 2018 | 1afbf66c-4ffb-44ff-a058-2fe1f44b9698 | multi |
Which of the following cell types are specific to a latent genital infection with HSV-2 | Latent infection by HSV-2 has been shown to occur primarily in the sacral ganglia, whereas HSV-1 latency has been demonstrated in trigeminal, superior cervical, and vagal nerve ganglia. Varicella- zoster virus remains latent in neural sensory ganglia. Ref:- Baveja textbook of Microbiology | 1 | Sacral ganglia | Neural sensory ganglia | Trigeminal ganglia | Vagal nerve ganglia | Microbiology | Virology | ba30ef45-e12c-4c58-a301-185542b5668f | single |
If a body is left undisturbed, for how long does post moem staining persists : | D i.e. Persists till merges with discolouration of putrefaction | 4 | Few hours | Few days | Few months | Persists till merges with discolouration of putrefaction | Forensic Medicine | null | 8fa85800-48b2-4749-8f5f-653aaad7ed1a | single |
Phage typing is useful as an epidemiological tool in all, except ? | Ans. is 'd' i.e., Shigella dysenteriae | 4 | Salmonella | Staph aureus | V. cholerae | Shigella dysenteriae | Microbiology | null | 8e048fb9-5de8-46f7-8882-b0898c7eac5e | multi |
Multifactorial inheritance is most likely to play a role in | Cleft lip and cleft palate, also known as orofacial cleft, is a group of conditions that includes cleft lip (CL), cleft palate (CP), and both together (CLP).] A cleft lip contains an opening in the upper lip that may extend into the nose. The opening may be on one side, both sides, or in the middle. A cleft palate is w... | 1 | Cleft lip | Marfan's syndrome | Down's syndrome | Erythroblastosis fetalis | Pathology | General pathology | fe94a1f7-2fa1-416b-b5cd-a3f044b8057b | single |
Which of the followign drugs require dose adjustment in renal failure? | Ans. (C) Streptomycin(Ref: Katzung 10/e p835 KDT 8/e p746)Streptomycin is an aminoglycoside and require dose adjustment in renal failure whereas doxycycline, rifampicin and cefoperazone are secreted in bile and do not require dose adjustment in renal failure. | 3 | Cefoperazone | Doxycycline | Streptomycin | Rifampicin | Pharmacology | Chemotherapy: General Principles | 0162b165-fe45-4660-a76b-9c9982150cd1 | single |
The learning theory of digit sucking was proposed by | The learning theory: Davidson (1967)
This theory advocates that non-nutritive sucking stems from an adaptive response.
The infant associates sucking with such pleasurable feelings as hunger. These events are recalled by sucking the suitable objects available, mainly thumb or finger. | 1 | Davidson, 1967 | Sears and Wise, 1982 | Johnson and Larson, 1993 | Sigmond Freud, 1905 | Dental | null | ce95c227-e06d-41b3-a47e-c9f125031d15 | single |
Which aery dilatation causes compression of 3rd pa of duodenum | Superior mesenteric aery: - Aery of mid gut Origin - L1 veebrae level . Regional anatomy of SMA: - It is crossed anteriorly by the splenic vein & the neck of pancreas. Posterior to it is the renal vein, the uncinate process & the inferior pa of duodenum (3rd pa). - This D3 pa can be compressed b/w two aeries: - Anterio... | 1 | Superior mesenteric aery | Gastroduodenal aery | Inferior mesenteric aery | Celiac aery | Anatomy | Small intestine and large intestine | 8e6d5c3d-2b96-4f38-9c61-5629b28b3c0e | single |
The surgery for hyperophic pyloric stenosis of infancy is | After laparotomy hyperophied muscle is cut along the whole length adequately until mucosa bulges out, then pyloromyotomy is done. in Heller&;s operation muscle of the cardiac are cut to allow passage of food ,and is done in achalasia cardia Truncal vagotomyis done by denervating the main branch which is supply in pylor... | 1 | Ramstedt's operation | Truncal vagotomy | Heller's operation | Delorme's operataion | Surgery | G.I.T | 0ca68dd1-02ec-4201-bf11-a02b25742c7b | single |
Testamentary capacity is the ability to: | Testamentary capacity (testament = will) is the mental ability to make a valid will. Will denotes any testamentary document. The requirement for a valid will are as follows. A written and properly signed and witnessed document must exist. The testator must be a major and of sound disposing mind at the time of making th... | 3 | Give evidence in a cou of law | Enter into a contract | Make a will | Give consent | Forensic Medicine | null | bea50b65-023e-4085-a4fc-52ea30549a39 | single |
Uveitis with raised intraocular tension is best managed by – | Keep in mind that:-
Treatment of uveitis in hypertensive uveitis (uveitic glaucoma) is topical steroid along with mydriatic-cycloplegics.
Treatment for reducing IOP in hypertensive uveitis (uveitic glaucoma) is antiglaucoma drugs (Timolol is the drug of choice). | 4 | Timolol | Atropine | Pilocarpine | Steroid | Ophthalmology | null | 7d897424-4c41-4d11-bcee-5ce9af5fbf25 | single |
Pin point pupil is seen in A/E : | D i.e. Barbiturate All are causes of constricted pupils but in? Barbiturate poisoning the pupils are usually slightly constricted & react to light by alternate contraction & dilation and dilate during terminal asphyxiaQ | 4 | Pontine haemorrhage | Organophosphorus poisoning | Opium poisoning | Barbiturate poisoning | Forensic Medicine | null | 700bd2c7-24d1-459f-b3a7-97aef7d008aa | single |
All are morbidity indicators execpt - | Ans. is `b' i.e., Doctor : population ratio Health change cannot be measured in specified unit. o So, different indicators have been defined which reflect health change in a community. o These indicators are called health indicators e.g. moality indicators, morbidity indicators, Disability rates. | 2 | Period of stay in hospital | Doctor : population ratio | Attendance at out patient depament | Notification rates | Social & Preventive Medicine | null | d1b969c8-9a46-4b6e-874c-1c54a6ddf5fe | multi |
False positive fistula test is associated with | False positive fistula test seen in: Congenital syphilis - Stapes footplate is hypermobile Meniere's disease - fibrous bands connecting uricular macula to Stapes footplate. Ref : Dhingra 7e pg 43. | 3 | Perilymph fistula | Malignant sclerosis | Congenital syphilis | Cholesteatoma | ENT | Ear | 1e9697dd-e24a-4254-9bc3-59f2bd2a1135 | multi |
NOT a feature of ligature strangulation: Kerala 08 | Ans. Incomplete ligature mark | 2 | Horizontal ligature mark | Incomplete ligature mark | Marked congested face | Sub-conjunctival hemorrhage | Forensic Medicine | null | 6db5c0e8-6556-4c69-a030-1aecf6318b46 | single |
A 32-year-old female is brought by his family with history of gradual onset of suspiciousness, muttering and smiling without clear reason, decreased socialization, and violent outbursts. Mental status examination revealed a blunt affect, thought insertion, impaired judgement and insight. The most likely diagnosis would... | Ans. C. SchizophreniaSchizophrenia is a disorder characterized by delusions, hallucinations, negative symptoms, aggressive behavior in clear consciousness. Altered sensorium is seen in organic conditions like delirium. | 3 | Delusional disorder | Depression | Schizophrenia | Anxiety disorder | Psychiatry | Schizophrenia | 2f8c8ce5-26b8-414a-97e7-e741341be72e | single |
In which of the following condition is Ground glass appearance of maxillary sinus seen? | Extra oral film taken in a case of maxillary fibrous dysplasia shows ground glass appearence. Intraoral film taken in this condition shows orange peel appearence. Fibrous dysplasia is an idiopathic skeletal disorder in which medullary bone is replaced by poorly organized structurally unsound fibro osseous tissue. Most ... | 4 | Maxillary Sinusitis | Maxillary Carcinoma | Maxillary polyp | Maxillary fibrous dysplasia | ENT | null | 2cbedaef-4449-4161-bc27-0f662e59d0a3 | single |
Peptidoglycans are found in large quantities in cell wall of: March 2009 | Ans. B: Gram positive bacteria The Bacteria (eubacteria), with the exception of the Chlamydias have a semirigid cell wall containing peptidoglycan. Gram negative bacteria's peptidoglycan layer is much thinner than in Gram-positive bacteria In general, the walls of gram positive bacteria have a simpler chemical nature t... | 2 | Virus | Gram positive bacteria | Gram negative bacteria | All of the above | Microbiology | null | beef8b2a-570a-4e6d-9299-c4eafef0db04 | multi |
Coincidental malignancy in the upper respiratory tract with inveed papillomas seen in | Coincidental malignancy in the upper respiratory tract with inveed papilloma is seen in 4%Malignant transformation of the tumor itself is seen in 8% | 3 | 0.10% | 2% | 4% | 5% | Microbiology | All India exam | b77253db-30c6-4d5f-a6a5-cebeb1b917ef | single |
Hepatic encephalopathy is aggravated by all except? | Hypokalemia is seen with overzealous use of diuretics and this will lead to dehydration and increased hepatic encephalopathy. Anemia associated with Gl bleeding worsens hepatic encephalopathy Constipation in hypothyroidism will worsen hepatic encephalopathy by increasing bacterial load. Drugs like barbiturates and anti... | 1 | Hyperkalemia | Anemia | Hypothyroidism | Barbiturates | Medicine | Hepatic encephalopathy & hepatic failure | dabec9b2-ae02-411b-a792-6f3e383d6647 | multi |
A female aged 30, presents with an episodic throbbing headache for past 4 yrs. It usually involves one half of the face and is associated with nausea and vomiting. There is no aura. Most likely diagnosis is | Migraine 2nd most common cause of a headache.Affects 15% of women and 6% of men over a one year period.Usually an episodic headache and associated with ceain features such as sensitivity to light, sound, or movement. Nausea and vomiting often accompany a headache.May be associated with other symptoms of neurologic dysf... | 1 | Migraine | Cluster headache | Angle closure glaucoma | Temporal aeritis | Medicine | All India exam | d727dd5f-d336-4ad2-a52b-3c3a9b537cbf | multi |
What is the type of voice in antrochoanal polyp- | Ans. is 'a' i.e., Hyponasal voice Clinical features of antrochoanal polypo Unilateral Nasal blockage (more on expiration than on inspirationo Obstruction may become bilateral when polyp grows into nasopharynx and starts obstructing opposite choana.o Hyponasal voiceo Mucoid nasal dischargeo Conductive deafness due to eu... | 1 | Hyponasal voice | Hoarse voice | Low pitched voice | High pitched voice | ENT | Polyp | e55c89a1-7340-4aca-939e-fa278715fc87 | single |
Deep white matter lesion with bilateral deep bright thalamic appearance is suggestive of | Ans. is 'c' i.e. Krabbe's disease Deep white matter lesion along with the involvement of thalamus suggests Krabbe's disease.Krabbe's disease is a leukodystrophy.LeukodystrophyIt is a term commonly used to refer to demyelination disorders.They are mainly due to genetic defects in the formation and maintenance of myelin.... | 3 | Alexander disease | Canavan's diseases | Krabbe's disease | Metachromatic leukodystrophy | Pediatrics | Endocrinology | ba81aeb9-d666-470d-aadc-17913046da14 | single |
What changes in GFR is expected in a 30-year-old lady with pre-eclampsia? | Pre-eclampsia is a state of hypeension in pregnancy associated with proteinuria but with or without pathological edema. It is defined as a multi-system disorder of unknown etiology characterised by development of hypeension to the extent of 140/90 mm Hg or more with protienuria after the 20th week of pregnancy in a pre... | 1 | Decreases | Increases | Remains the same | None of these | Gynaecology & Obstetrics | null | 9810e244-4a8f-4571-bd4b-51f266f12428 | multi |
Adies aegpti index at airport - | (C) (< 1) (258 - Park 22nd)AEDES AEGYPTI INDEX: This is a house index and is defined as "the percentage of houses and their premises in a limited well-defined area, showing actual breading of Aedes - aegypti larvae"* This index should not be more than 1 percent in towns and seaports in endemic areas to ensure freedom f... | 3 | 0 | 1 | <1 | 2-Jan | Social & Preventive Medicine | Communicable Diseases | f36ec928-6f46-4017-b540-f962b8695aaf | single |
Following are the mature mineralized matrix marker of the periodontal ligament except: | Markers for Periodontal Ligament Stem Cells
1. Bone Marrow Markers
STRO-1
2. Perivascular Cell Markers
CD146
αSMA
Pericyte associated antigen 3G5
CD106
3. Mature Mineralized Matrix Markers
Alkaline phosphatase
Osteonectin
Osteopontin
Osteocalcin
Bone sialoproteins
4. Connective Tissue Protein Markers
Type I and ... | 1 | Type 1 and type 3 collagen. | Osteonectin. | Alkaline phosphate. | Osteopontin. | Dental | null | 1b296b1d-b1c2-4ad9-849a-dc8aeeed7603 | multi |
Which among the following anti-HIV drugs is also used to treat viral hepatitis B? | null | 2 | Enfuvirtide | Lamivudine | Efavirenz | Ritonavir | Pharmacology | null | 2b297633-cb2b-488f-8ae0-043853ee4d09 | single |
Prolactin secretion is decreased by | null | 4 | L- dopamine | Bromocriptine | Diphenhydramine | All of the above | Medicine | null | 3156a3f3-8388-4af9-bd83-eb3a2ca0a8c6 | multi |
The commonest presentation of meckel's diverticulum is - | null | 1 | Bleeding | Obstruction | Diverticulitis | Intussception | Surgery | null | edd77f45-65d4-4768-96fb-dad98dab520d | single |
Histocompatibility complex associated with narcolepsy - | null | 1 | DR2 | DR3 | DR4 | B4 | Medicine | null | 1082bbb7-ea54-4809-9f8f-c6520c062f33 | single |
Strongest attachment of Zonule is at - | The lens is suspended in the eye by zonules which are inseed on the anterior and equatorial lens capsule and attached to the ciliary body. REF IMG | 2 | Equator | Just anterior to equator | Posterior to equator | Posterior lobe | Ophthalmology | Lens | 952a1c0f-50b4-45ea-8906-f1297ca9e5a5 | single |
Thyroxine is used in the treatment of which thyroid cancer: | null | 4 | Medullary | Radiation induced | Anaplastic | Papillary | Pharmacology | null | 5828aa1e-2359-4dd4-a7ef-2887d6501f62 | single |
Most cardiotoxic local anesthetic - | Ans. is 'b' i.e., Bupivacaine o Bupivacaine is the most cardiotoxic LA (Ropivacaine is a newer bupivacaine congener with less tardio toxicity).Important facts about LAso Chlorprocaine is the shortest acting LA.o Dibucaine is the longest acting, most potent and most toxic LA.o Procaine & chlorprocaine are least potent L... | 2 | Procaine | Bupivacaine | Cocaine | Lidocaine | Anaesthesia | Miscellaneous (Local and Regional Anesthesia) | 4f1d5eaf-0429-41ee-8739-3b2de8c51a86 | single |
In sickle cell anaemia, there is | null | 1 | 75 to 100% haemoglobin | 10 to 20% haemoglobin | 20 to 30% haemoglobin | 50 to 60% haemoglobin | Pathology | null | a38f0d95-966d-4bde-bf69-b1f08854bb73 | single |
Bochdalek hernia occurs through | A hernia through foramen Bochdalek (through the pleuroperitoneal canal) (95% left-sided, only 5% right sided) * It is a commonest congenital diaphragmatic hernia. * This is a developmental defective condition, due to a failure of fusion of pleuroperitoneal canal leaving a direct communication between pleura and periton... | 1 | Diaphragm | Lumbar triangle | Femoral region | obturator canal | Surgery | G.I.T | a3d1f5d2-0cfb-4e3d-9082-2f51a0bbee3b | single |
A 37-year-old woman was admitted to the emergency department with high fever (39.5deg C), nausea, and vomiting. Physical examination revealed increased abdominal pain in the paraumbilical region, rebound tenderness over McBurney's point, and a positive psoas test. Blood tests showed marked leukocytosis. Which of the fo... | Appendicitis is often characterized by acute inflammation and is indicated with both a positive psoas test and rebound pain over McBurney's point. McBurney's point lies 1 inch lateral to the midpoint of an imaginary line in the right lower quadrant, joining the anterior superior iliac spine and the umbilicus. In patien... | 2 | Ectopic pregnancy | Appendicitis | Cholecystitis | Kidney stone | Anatomy | Abdomen & Pelvis | 24bbce20-dd17-4294-ae1b-ed3d0b0b78b1 | single |
Drug used to treat tremors in hypehyroidism is: September 2008 | Ans. B: Propranolol Beta-blockers such as propranolol help control many of the symptoms of hypehyroidism. These drugs can slow a fast hea rate, reduce tremors, and control anxiety. Beta-blockers are paicularly useful for people with extreme hypehyroidism and for people with bothersome or dangerous symptoms that have no... | 2 | Adrenaline | Propranolol | Noradrenaline | Dopamine | Pharmacology | null | ad5ef257-584b-4364-b381-fbb3ce491b7b | single |
Omalizumab is administered by which route: | Patients should be given a 3-4 month trial of therapy to show objective benefit. Omalizumab is usually given as a subcutaneous injection every 2-4 weeks and appears not to have significant side effects. Ref: Harrison's principle of internal medicine 17th edition, chapter 248. | 4 | Inhalation | Intravenous | Intranasal | Subcutaneous | Medicine | null | 108331f6-cf19-4734-bf85-8f55133bbaf4 | single |
According to the Bismuth / Strasberg classification 'Cystic blow out' is classified as: | Cystic blow out' is a type of biliary duct injury in cholecystectomy patient. According to Strasberg classification it falls into Type A injury. Ref: Complication in Surgery By Michael W. Mulholland, Gerard M. Dohe, 2nd Edition, Page 432 | 1 | Type A | Type B | Type C | Type D | Surgery | null | 5e9a055f-4270-4bea-9c94-2bda29b097fd | single |
The drug of choice in treatment of inflantile spasms is | Infantile spasms:-
West syndrome
Onset : 3-8 months of life
Characterised by combination of salaam spells( sudden dropping of the head and flexion of arms), developmental retardation, hypsarrythmia on ECG.
Causes-
Hypoxic ischemic encephalopathy
Neurocutaneous syndromes
Perinatal infections
Hemorrhage
Injury
Metabol... | 4 | Phenytoin | Phenobarbitone | Carbamazepin | ACTH | Pediatrics | null | d4f1b7b4-d096-409d-98f2-abbba360b7ac | single |
Albendazole is effective against all of the following except : | null | 3 | Roundworm | Hookworm | Tapeworm | Pinworm | Pharmacology | null | b8a3e52c-2590-41b7-b2ca-f5355a11789a | multi |
In a case of chronic arsenic poisoning all of the following samples are sent for laboratory examination, EXCEPT: | Arsenic is present in blood only during acute poisoning. In chronic poisoning arsenic gets deposited in the bone, keratin tissues, hair, nail and skin for many years. In the bone arsenic replaces phosphorous and remains for many years. Arsenic appear in the hair and nails within hours of ingestion. Neutron activation a... | 4 | Nail clippings | Hair samples | Bone biopsy | Blood sample | Forensic Medicine | null | 8b29d847-798f-4840-a4fe-21093c58f17d | multi |
This rash appeared 9 hours after a scuba dive. What is the diagnosis? | Answer A. Decompression sicknessCutis marmorata is a dermal manifestation of decompression sickness. Initially, there is erythema accompanied by pruritus, and then the rash spreads irregularly and deepens in color. It develops a mottled appearance, with areas of pallor surrounded by cyanotic patches. During recompressi... | 1 | Decompression sickness | Jellyfish envenomation | Mycobacterium marinum infection | Phylum Porifera contact dermatitis | Medicine | Infection | 73ecf307-eeaa-4540-b0b2-baaae085eb48 | single |
A patient with hip dislocation with limitation of Abduction at hip and flexion and internal rotation deformity at hip and shortening. Diagnosis is: | (c) Posterior dislocationExplanationSince the question mentions limitation of abduction, hence there is adduction deformity along with flexion and internal rotation deformity. Thus this is a case of Posterior dislocation of hip.Position of hipPattern of InjuryFlexion, adduction, internal rotationPure posterior dislocat... | 3 | Central dislocation | Anterior dislocation | Posterior dislocation | Fracture dislocation | Orthopaedics | Pelvis & Injuries | 950da181-d785-4ae3-82ee-b5f65c69c546 | single |
Cyanide poisoning acts by : | C i.e. Inhibit cellular respiration | 3 | Inhibiting DNA synthesis | Inhibiting enzymes of proteins synthesis | Inhibiting cellular respiration | Inhibiting protein breakdown | Forensic Medicine | null | 6e3b8384-981f-4f58-a95a-f4f10cfe1c5e | single |
A 28 year old female patient with patches of burns and swelling of arm. Histopathological findings reveal swelling of endopasmic reticulum, blebs from cell membrane, loss of microvilli, presence of myeloid bodies and no changes in nucleus. Which type of injury is seen in this patient? | Reversible cell injury:-
→ Hypoxia is the most common cause of cell injury.
→ Oxygen is an important requirement of mitochondria, for the formation of ATP, therefore hypoxia will result in earliest involvement of mitochondria, resulting in decreased formation of ATP.
→ Important organelles affected are
Cell membranes ... | 4 | Irreversible cell injury | Autolysis | Pyroptosis | Reversible cell injury | Pathology | null | db9f83fb-de1b-4945-ae67-72701a4729b1 | single |
Break bone fever is caused by - | Ans. is 'c' i.e., Dengue fever o Break bone fever (Saddle back fever) is caused by dengue virus.Dengue fevero Dengue fever is caused by arboviruses (at least 4 serotypes have been recognized)o It is transmitted by Aedes (Aedes aegypti is the main vector).o The reservoir of infection is both man and mosquito,o The trans... | 3 | Yellow fever | Japaneseencephlitis | Denguefever | KFD | Microbiology | Arboviruses | 248e7391-5985-42ca-8499-994745731c16 | single |
Erythroblastosis fetalis is an example of which type of hypersensitivity reaction ? | Ans. is 'b' i.e., Type II Erythroblastosis fetalis and blood transfusion reactions are type II hypersensitivity reactions. | 2 | Type I | Type II | Type III | Type IV | Microbiology | null | 15bda01d-c3e2-448c-b1d6-0819ebddce5d | single |
The movement that occurs in the horizontal plane when the mandible moves into a lateral excursion is | null | 2 | Horizontal axis | Vertical axis | Sagittal axis | Trans saggital axis | Dental | null | 4672e727-3b76-4d44-b209-2a00f0232734 | single |
Sho-chain fatty acids produced by bacteria are maximally absorbed in | Sho-chain fatty acids are produced in the colon, by the action of colonic bacteria on complex carbohydrates, and other dietary components that could not be digested in the small intestine. These sho-chain fatty acids are absorbed from the colon. | 4 | Duodenum | jejunum | ileum | Colon | Physiology | Gastrointestinal System | c1ee90a1-44ea-4471-acd0-f893ad6c8ea6 | multi |
Mechanism of action thiazide is ? | Ans. is 'a' i.e., Na+ Cl- synpo inhibitor | 1 | Na+Cl- sympo inhibitor | Na+K+ sympo inhibitor | Carbonic anhydrase inhibitor | Osmotic diuresis | Pharmacology | null | 16647d47-3bbb-477c-b17a-f077faa3ea1a | single |
All of the following are formal thought disorder EXCEPT: | Ans. B i.e. DelusionDelusion is a disorder of thought content (NOT a formal thought disorder/disorder of thought process)DelusionDisorder of thought;False unshaken belief not amenable to reasoningSchizophrenia- Formal thought disorderLoosening of association-Formal thought disorderMania-Stream of thought disorder | 2 | Schizophrenia | Delusion | Loosening of association | Mania | Psychiatry | null | 5a1e1128-33c4-4a71-8460-0277d121156c | multi |
Open Neural tube defect is best diagnosed by: | Amniotic fluid acetycholinesterase | 4 | USG | Maternal serum alpha fetoprotein | X-ray | Amniotic fluid acetycholinesterase | Gynaecology & Obstetrics | null | c3f883f9-199a-495f-a7ae-a2d52c89cf43 | single |
Angiosarcoma of the liver is associated with - | Angiosarcoma of the liver is associated with exposure to →
1) Vinyl chloride,
2) Arsenic,
3) Thorotrast | 4 | Nickel | Chromium | Cadmium | Arsenic | Pathology | null | 044262fd-2814-4028-9137-9937be78db85 | single |
Omega shaped epiglottis is seen in: | Ans. (b) LaryngomalaciaRef: Dhittgra's ENT 6th ed./ 295LARYNGOMALACIA* The most common congenital disease of larynx is Laryngomalacia.* Laryngeal cartilages are extremely soft and flabby in a child with laryngomalacia.* Most common clinical presentation of laryngomalacia: Stridor* The stridor is mainly inspiratory and ... | 2 | Epiglottitis | Laryngomalacia | Epiglottis CA | Tuberculosis | ENT | Larynx | ca17edb2-233d-4c52-8774-8e71a1ce269b | single |
A 21-year old male presents with exertional dyspnea, raised JVP and loud P2. ECG shows right axis deviation. All of the following conditions are possible except : | null | 3 | Atrial septal defect | Mitral stenosis | Ostium primum | Pulmonary thromboembolism | Medicine | null | e8466338-c240-4840-8c8a-4550260f5917 | multi |
Ptosis may occur due to damage to: | Ptosis is the drooping eyelid, may be seen in some clinical cases.
Oculomotor ptosis due to paralysis of the levator palpebrae (e.g., transtentorial herniation).
Oculosympathetic ptosis due to paralysis of the superior tarsal (Muller) muscle as seen in Horner syndrome. This is a very slight ptosis, or pseudoptosis (e.... | 2 | Trochlear nerve | Oculomotor | Trigeminal nerve | Superior oblique muscle | Anatomy | null | 6f1aa9e9-dfc1-49f5-aed3-10d008964815 | single |
Fibroids in pregnancy should be removed : | Should not be removed | 4 | In pregnancy | During cesarean section | In the early puerperium | Should not be removed | Gynaecology & Obstetrics | null | 150ebfdc-9b11-4cc5-89ef-385cb37391cf | single |
Rule of Hasse is used to determine - | RULE OF HAASE: This is a rough method of calculating the age of the fetus. The length of the fetus is measured from crown to heel in centimeter During the first 5 months of pregnancy, the square root of the length gives an approximate age of the fetus in months, eg: a fetus length is 16cm is 4 months. HAASE'S MODIFICAT... | 1 | The age of fetus | Height of an adult | Race of a person | gender of fetus | Forensic Medicine | Identification | 294a6a99-9437-4189-8c5c-9cd4379f0639 | single |
Which of the following is an example of physiological antagonism ? | null | 2 | Heparin–Protamine | Prostacycline–Thromboxane | Adrenaline–Phenoxybenzamine | Physostigmine–Acetylcholine | Pharmacology | null | dff35069-1f68-4384-8d25-dcdf2aca6ed0 | single |
According to signal transductions mechanism, GABA B is which type of receptor? | Five basic mechanisms of transmembrane signaling are well understood. Each uses a different strategy to circumvent the barrier posed by the lipid bilayer of the plasma membrane. These strategies use: a lipid-soluble ligand that crosses the membrane and acts on an intracellular receptor. a transmembrane receptor protein... | 3 | Ligand gated receptor | Nuclear receptor | G protein coupled receptor | Enzymatic receptor | Pharmacology | DNB 2018 | 8af3b0e6-1e89-4ba9-8b8a-895fc8b59490 | single |
A 26 year old female patient complains of discoloured teeth. Intra-oral examination reveals generalized intrinsic tetracycline stains. Which of the following is an effective and esthetic treatment in this case? | Bleaching tetracycline-stained teeth is difficult, some clinicians advocate intentional endodontic therapy along with the use of an intracoronal nonvital bleaching technique to overcome this problem. Although the esthetic result appears much better than that obtained from external bleaching, this approach involves all ... | 4 | External bleaching | Intracoronal bleaching | Veneers | Full coverage crowns | Dental | null | d02a62d3-231a-4572-af84-a9f649fd0089 | single |
Selective media for gonococci- | null | 1 | Thayer martin media | L J medium | DCA medium | Mac Conkey agar | Microbiology | null | 6512cafc-09b0-4400-8e60-15689c71157c | single |
A 3 month baby will have – | null | 2 | Pincer grasp | Head control | Sitting with support | Transfer objects | Pediatrics | null | ab8c97ca-065c-4e96-97aa-6939512359db | single |
A 65-year-old man is brought to the hospital after being hit by a car. His blood pressure is 150/90 mm Hg, and pulse is 120 bpm. There is deformity just below the left knee and no distal pulses palpable in that leg. Plain films show proximal tibia and fibula fractures. What is the next step in management? | In a stable patient presenting with peripheral vessel occlusion following blunt trauma, angiography is indicated to plan the appropriate operative approach. An angiogram can also document preexisting arteriosclerosis, collateral circulation, and distal runoff. Doppler ultrasound is useful to localize the injury site bu... | 2 | Operative intervention to restore flow with an arterial shunt | Angiography | Doppler ultrasound | Operative reduction and internal fixation | Surgery | Trauma | 6884e2c8-e825-4e62-96af-63edd6453ee6 | multi |
All are true regarding Klinefelter's syndrome except: | Ans: B (Webbing of neck) Ref: Robbins Pathologic Basis of Disease, 8th edition.Explanation:Webbing of neck is characteristically seen in Turner's syndromeKlinefelter SyndromeMale hypogonadism that occurs when there are two or more X chromosomes and one or more Y chromosomes.MC genetic disease involving the sex chromoso... | 2 | Small Testes | Webbing of neck | Gynecomastia | Increased FSH levels | Pathology | Mendelian Disorders: Single-Gene Defects | d9a4bfd2-ea44-4fdc-9517-bd11a2c73820 | multi |
32 yr old with diarrhea, flushing. On CT multiple lesions seen in liver. Primary disease is in - | Intestinal amoebiasis - amoebic dysentery Most amoebic infections are asymptomatic. The incubation period of amoebiasis ranges from 2 weeks to many years, followed by a chronic course with abdominal pains and two or more unformed stools a day. Offensive diarrhoea, alternating with constipation, and blood or mucus in th... | 3 | Esophagus | Appendix | Small bowel | Stomach | Medicine | G.I.T | 51866632-87d0-4299-a4a3-c52641cb7c35 | multi |
The premaxilla harbouring maxillary central incisors is embryonically derived from: | null | 1 | Median nasal process. | Lateral nasal process. | Medial nasal process. | None. | Dental | null | e0811261-8d9a-49fc-ad7e-851e04487ba2 | multi |
A female patient presented with a firm mass of 2 x 2 cmsin the upper outer quadrant of the breast. She gives afamily history of ovarian carcinoma. The investigationthat needs to be done to assess for mutation is : | C-myc gene | 2 | p53 | BRCA-2 | Her 2/Neu gene | C-myc gene | Pathology | null | b5b9fc21-b450-4636-a276-01198964241f | single |
Ligature pressure that should be used to resist spread of poison in elapidae poisoning: WB 11; MAHE 12 | Ans. 50-70 mm Hg | 3 | < 10 mm Hg | 20-30 mm Hg | 50-70 mm Hg | > 100 mm Hg | Forensic Medicine | null | 4ae90be6-3cd0-4eff-8ec0-0d86730651b0 | single |
In 7 year old posterior fossa mass with cyst formation, hypodense on CT, hyper intense on T2WI and showing post gadolinium nodule enhancement is | C i.e. Astrocytoma Posterior Fossa tumors in children Features Astrocytoma Ependymoma Medulloblastoma Cyst Formation Very cominonQ Common Rare CT scan IlypodenseQ Rare Isodense No Hyperdense Yes (15-40%) CSF seeding Transforaminal spread No Yes No Calcification -10% 40-50% 10-15% T2WI Hyper (intense) Hyper/Iso Iso T1 W... | 3 | Medulloblastoma | Ependymoma | Astrocytoma | Cysticercous | Radiology | null | ec328264-b521-4fca-a119-07bd211c3394 | single |
True about silicosis all except: | Ans: d -Fibrotic change can be reversed after stopping exposureSilicosis is progressive & what is more impoant is that silicotics are prone to tuberculosisThere is no effective treatment for silicosis. Fibrotic changes that have already taken place cannot be reversedNodular fibrosis, more frequent in apex & posterior b... | 4 | Caused by exposure of silica oxide | Severe exposure- whole lung lavage may helpful in allet_ing symptoms | Fibrosis of upper lung | Fibrotic change can be reversed after stopping exposure | Social & Preventive Medicine | null | 63a65d65-8543-47b6-b55f-9cb8f0c3a3f0 | multi |
Mechanism of action of tranexamic acid in controlling bleeding is? | Ans. (a) Inhibits plasminogenRef Lippincott's Pharmacology 4/e, p 265 | 1 | Inhibits plasminogen | Promote platelet aggregation | Cause vasoconstriction | Promote fibrin synthesis | Pharmacology | Antiplatelets and Fibrinolytics | 113dc09d-4f71-44c2-a657-6f3b809cd712 | single |
How would a drug that competes with acetylcholine for receptors at the motor end plate effect of skeletal muscle. it would be? | Refer kDT 6/e p 340 Drugs competing with acetylcholine at neuromuscular Junction are competitive or non depolarizing neuromuscular blockers. These drugs are used as muscle relaxants. In contrast to depolarising muscle relaxant, these do not cause initial fasciculations | 3 | Produce uncontrolled muscles spasm | Cause of muscle to contract and unable to relax | Cause muscle to relax and be unable to contract | Make the muscle more excitable | Pharmacology | Autonomic nervous system | 52b3f3fd-763e-4929-9240-2c525b18cae4 | single |
During neonatal resuscitation, the chest compression to ventilation ratio is | It is important to ventilate in between chest compressions. A positive breath should follow every third chest compression(chest compression to ventilation ratio is 3:1).
In one minute, 90 chest compressions and 30 breaths are administered(120 events).
To obtain this, the chest should be compressed 3 times in 1.5 seco... | 4 | 15:01 | 5:01 | 10:01 | 3:01 | Pediatrics | null | dda728fa-b94d-4c03-a625-8bdc411fead7 | single |
Pneumatocele is commonest in: | Staphylococcal pneumonia | 2 | Pneumococcal pneumonia | Staphylococcal pneumonia | H. influenzae pneumonia | Viral pneumonia | Radiology | null | c4180b6f-67de-4243-8fcc-078a59dc94e1 | single |
Molar pregnancy can be best diagnosed by: | Ans. b (Ultrasound study) (Ref: Grainger, Diagnostic Radiology, 4th/pg.2213 & Rumac, Diagnostic Ultrasound, 2nd/ pg.1359)MOLAR PREGNANCY# Molar pregnancy includes:- complete and- partial molar pregnancy.# The greatest diagnostic accuracy is obtained from the characteristic ultrasonographic appearance of hydatidiform mo... | 2 | Clinical history and examination | Ultrasound study | Laproscopy | CT Scan | Radiology | Obstetrics And Gynaecology | 3c8506bc-197a-4662-84f7-9f9f9e67a604 | single |
Indicator for vector burden on human malaria is:- | Ans. (A) Man biting rate(Ref: Park Text book of PSM 25th ed; pg. 342)Vector burden may be denoted by the term-anthrophilismMan biting rate (biting density): It is defined as the average incidence of anopheline bites per day per person. It is determined by standardized vector cache on human bait.Sporozoite rate: It is p... | 1 | Man biting rate | Inoculation rate | Slide positive rate | Human blood index | Social & Preventive Medicine | Communicable Diseases | 352636fd-8735-4e3c-864f-18d0f0489cb1 | single |
Increased osmolar gap is not seen in poisoning of- | Causes of High-Anion Gap Metabolic Acidosis *Lactic acidosis * Toxins *Ketoacidosis * Ethylene glycol Diabetic * Methanol Alcoholic * Salicylates Starvation * Propylene glycol *Pyroglutamic acid (5-oxoproline) *Renal failure (acute and chronic) reference : harrisons principles of internal medicine,19 E , page 318 | 1 | Para-aldehyde | Acetones | Methanol | Ethylene glycol | Medicine | Fluid and electrolytes | a7f40ce2-cd62-4dee-9201-a7d6162e4169 | single |
High levels of HBeAg in serum indicates | null | 2 | HBeAg is not seen in the serum | High infectivity of the virus | Low infectivity of the virus | Recovering stage | Social & Preventive Medicine | null | 4041d199-785a-48cf-882e-5ff2fbb67156 | single |
A 40 year old male brought to the emergency room with a stab injury to the chest.On examination pt is found to be hemodynamically stable. The neck veins are engorged and the heart sound are muffled .The following statements are true for this pt except: | Ans. is 'b' i.e. Immediate emergency room thoracotomy should be done There is no need for emergency thoracotomy in a hemodynamically stable ptCardiac tamponade is quite common in stab injuries to the chest.* The classical sign of tamponade are-:Muffled heart sounds*Distended neck veins* -- k/a Beck Triad*Hypotension*Th... | 2 | Cardiac tamponade is likely to be present. | Immediate emergency room thoracotomy should be done. | Echocardiogram should be done to confirm pericardial blood. | The entry wound should be sealed with an occlusive dressing. | Surgery | Thoracic Injury | 9d491219-d0e5-48f4-ba57-800be4431a36 | multi |
Tramadol is | Ans. d (Opioid analgesic). (Ref. KD Tripathi, Pharmacology/6th. 453)# Tramadol is synthetic centrally acting opioid analgesic having modest affinity for ji receptors.# Unlike other opioids, it inhibits reuptake of NA and 5-HT and thus activates monoaminergic spinal inhibition of pain.# Its oral bioavailability is good ... | 4 | Antiflatulent | Antireflux drug | Beta-blocker | Opioid analgesic | Pharmacology | C.N.S | b0d8e08d-51dc-422a-ad70-a3e0595b4e7f | single |
Dark ground microscopy is used to see - | Dark ground/ Darkfield microscope
Very slender organisms such as spirochetes and filamentous organisms such as flagella are not visible under ordinary illumination.
The contrast in dark field microscopy gives an illusion of increased resolution so that these structures can be seen under the dark field microscope.
... | 2 | Refractile organisms | Flagella | Capsule | Fimbriae | Microbiology | null | 600b7a9a-5684-4712-be5e-d2f1e1469a19 | single |
Which of the following can be used as root canal filling materials | null | 4 | Cements and plastic materials | G.P. Points | Silver points | All of the above | Dental | null | bba4089c-0bc3-4acd-b91f-801b5891380a | multi |
False about vagina is : | Rich in glands | 2 | Paly or wholly derived from urogenital sinus | Rich in glands | Lined by stratified epithelium | Posterior fornix longer than anterior fornix | Gynaecology & Obstetrics | null | f4a2168f-3235-4d98-aa79-661d87fcbdf0 | multi |
Prolactin secretion is inhibited by - | Ans. is 'd' i.e., Bromocriptine o Prolactin is under predominant inhibitory control of hypothalamus through prolactin releasing inhibitory hormone (PRIH). o PRIH is a dopamine that acts on pituitary lactotrope D, receptor. So, Dopaminergic agonists decrease plasma prolactin levels. These agonists are : Dopamine Cobergo... | 4 | Dopamine antagonist | GABA | Neurophysin | Bromocripitine | Pharmacology | null | 908a356a-e56c-42b4-9444-d8819462d716 | single |
Method of application of neutral sodium fluoride according to Knutson's technique involves all except- | Method of application of neutral sodium fluoride according to Knutson's technique-
If the sodium fluoride reagent is pure and uncontaminated, this solution has a pH of 7. Treatments are given in a series of four appointments.
At the initial appointment, the teeth are first cleaned with aqueous pumice slurry and then ... | 3 | At the initial appointment, the teeth are first cleaned with aqueous pumice slurry and then isolated with cotton rolls and dried with compressed air. | The sodium fluoride solution applied on the teeth with cotton-tipped applicator stick is allowed to dry for 3 to 4 minutes. | A second, third and fourth fluoride application, each preceded by a prophylaxis, is scheduled at intervals of approximately one week. | The four-visit procedure is recommended for ages 3, 7, 1 1 and 13 years. | Dental | null | 57fcffb9-5d86-45fe-8365-4a8339643ae8 | multi |
Disadvantage of radioactive iodine include the following except: | Radioactive iodine emits beta particles that destroy some thyroid tissue and impair the ability of the remaining follicles to replicate; hence once the patient becomes euthyroid, chances of relapse are negligible. Though the amount of radioactive iodine to be administered is estimated by the size of the gland and its i... | 2 | Hypothyroidism | High chances of relapse | Delayed therapeutic effect | Development of thyroid carcinoma | Pharmacology | null | e530aeef-ed12-4384-ae0d-9e178feb8c1c | multi |
A 32-year-old female patient asks you what is the soft, thin ridge of tissue that she can feel running forward across the masseter muscle toward her upper lip. You reassure her that is perfectly normal. Which of the following is the most likely structure she is feeling? | The parotid duct, also known as the Stensen's duct, crosses the masseter muscle transversely and extends to the oral cavity. The facial artery can be palpated in the groove anterior to the mandibular angle. The facial vein lies anterior to the artery, passing toward the angle of the lips, but does not ascend in close p... | 3 | Facial artery | Maxillary artery | Parotid duct | Marginal mandibular branch of facial nerve | Anatomy | Head & Neck | eb3110cb-5cc2-4938-86e6-3fe732f7ea0f | single |
All of the following are the mode of transmission of leprosy except - | <p> Mode of transmission of Leprosy are droplet infection, contact transmission,insect bite,tattooing needles,breast milk,trans placental . Reference:Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:317-318 <\p> | 2 | Breast milk | Blood transfusion | Transplacental spread | Droplet infection | Social & Preventive Medicine | Communicable diseases | 74c567fb-16ba-424e-83b0-d34ebb106c77 | multi |
Sickle cell disease is due to | (Point mutation) (628-R) (227-426-Basicpathology> 8th)Sickle cell disease is an important hereditary hemoglobinopathy, a type of disease characterized by production of defective hemoglobins.Sickle cell disease is caused by a point mutation at the sixth position of the b-globin chain leading to the substitution of a val... | 1 | Point mutation | From shift mutation | Nucleotide receptor blockage | Non sequence mutation | Pathology | Blood | 2a289b3b-7a93-470f-8913-51b181f9202f | single |
Which is the commonest Post splenectomy infection- | null | 3 | Streptococcus pyogenes | Staphylococcus aureus | Streptococcus Pneumoniae | Pseudomonas aeruginosa | Surgery | null | 34edf79a-1888-4e12-be4b-7f57a47d4bda | single |
Generation time of E-coli is | (20 minute) (271- Ananthanarayan 8th, 30- Chakrahorthy 2nd)* Many bacteria reproduce by binary fission and the average time required for the population, or the biomass, to double is known as generation time or doubling time.GENERATION TIME* Lepra bacillus - 24 Days* Tuberculous bacillus - 20 hours* Coliform E.coli - 20... | 2 | 20 days | 20 minutes | 20 hours | 20 second | Microbiology | Bacteria | a5478124-ad38-4b92-bb45-e9e971cfad74 | single |
Fungicidal drug used orally for treatment of onychomycosis | Onychomycosis is a fungal infection of the nail causing yellow discoloration of the nail usually caused by a dermatophyte .Among the given drugs only terbinafine given orally. AMB given iv or lipososmal form. Ref:KDT 6/e 765 | 3 | Amphotericin B | Clotrimozale | Terbinafate | Gresiofulvin | Pharmacology | All India exam | 7ff4d5e3-df37-4ab1-8b2a-d71a4b1ee7af | multi |
Which of the following is primary cell line - | Primary cell cultures:These are normal cells freshly taken from the body and cultured. Common examples are monkey kidney,human embryonic kidney,human amnion and chick embryo cell cultures. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO:435 | 1 | Chick embryo fibroblast | Hela cells | Vero cells | WI-38 | Microbiology | Virology | be6f298d-f621-4772-8054-4d68e9edb1e7 | single |
Complication of vernal keratoconjunctivitis is | Keratoconus (conical cornea) is a noninflammatory bilateral (85%) ecstatic condition of the cornea in its axial pa. It usually stas at pubey and progresses slowly. Keratoconus may be associated with :Ocular conditions e.g. ectopia lentis, congenital cataract, aniridia, retinitis pigmentosa, and vernal keratoconjunctivi... | 2 | Cataract | Keratoconus | Retinal detachment | Vitreous hemorrhage | Ophthalmology | Conjunctiva | 7810ee8a-7bb6-4d25-bca9-af0c6d082f9d | single |
Why do direct filling golds have to be flamed before insertion into the cavity preparation? | Proper desorption is a matter of heating long enough at a temperature that removes contaminants and in the case of powdered gold, that burns away the wax.
Ref:Phillip’s Science of Dental Materials ed 12 pg 414 | 1 | To remove contaminants | To make gold soft | To form oxide layer on the surface | All of the above | Dental | null | a42e35a6-4e87-4b58-bef0-e817351b34fe | multi |
MHC CLASS III CODES for all except – | null | 1 | complement C3 | properdin | TNF –alpha | heat shock proteins. | Microbiology | null | aaf06910-9671-41c9-9ca6-200df57deff3 | multi |
'Ring vaccination' is | Ring vaccination is a strategy to inhibit the spread of disease by vaccinating only those who are most likely to be infected. | 3 | Given by a ring shaped machine | Given to produce a ring lesion | Given around 100 yards of a case detected | Given around a mile of a case | Social & Preventive Medicine | Epidemiology | ce45f9ff-74f7-4b6a-b7ba-a57f64fa3f4c | single |
SSRIs should be carefully used in the young for the management of depression due to increase in? | Ans. C. Suicidal ideationIn 2003, th UK Medicine and Health Care products regulatory agency concluded that all SSNs, with the exception of fluoxetine, were contraindicated in the treatment of depression in young people due to increase in suicidal ideation and dubious efficacy. | 3 | Nihilism ideation | Guilt ideation | Suicidal ideation | Envious ideation | Psychiatry | null | 7b968f6a-620d-4c95-957b-4b5595f7342b | single |
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