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LONG-TERM TREATMENT WITH APIXABAN OF PARTICIPANTS FOLLOWING CONCLUSION OF AVERROES Abstract: Background: AVERROES, a randomized trial in high‐risk patients with atrial fibrillation, unsuitable for vitamin K antagonist therapy, demonstrated the efficacy and safety of apixaban compared to aspirin for stroke prevention. ...
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Secondary Outcomes From the Child/Adolescent Anxiety Multimodal Study: implications for Clinical Practice Abstract: Controlled evaluations comparing medication, cognitive‐behavioral therapy (CBT), and their combination in the treatment of youth anxiety have predominantly focused on global ratings by independent evalua...
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Efficacy and safety of relugolix in black men with advanced prostate cancer: a subgroup analysis from the randomized, phase 3 HERO study versus leuprolide Abstract: Background: Prostate cancer disproportionately impacts Black men, with a higher incidence and worse outcomes relative to other races (Siegel DA, MMWR Morb...
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Efficacy and safety of foslevodopa/foscarbidopa versus oral carbidopa/levodopa in advanced parkinson's disease patients: design of a phase 3, randomized, double-blind, double-dummy, active controlled 12-week trial Abstract: Objective: Efficacy and Safety of Foslevodopa/Foscarbidopa Versus Oral Carbidopa/Levodopa in Ad...
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Short-course antimicrobial therapy for paediatric respiratory infections (SAFER): a multicentre, randomized, controlled, blinded, noninferiority trial Abstract: Background: Community‐acquired pneumonia (CAP) is a common occurrence in childhood; consequently, evidence‐based recommendations for its treatment are require...
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Effect of anacetrapib on ABCA1-specific cholesterol efflux capacity: a substudy of the define trial Abstract: Background: Impaired reverse cholesterol transport is associated with increased atherosclerosis. Cholesterol efflux from macrophages (CEC) is the initial step of reverse cholesterol transport and is inversely ...
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Influence of genetic polymorphisms on the response to tramadol and ibuprofen in patients with moderate-to-severe pain Abstract: The aim of this study was to evaluate the impact of several polymorphisms on the analgesic effect of ibuprofen and tramadol. We analysed 81 patients with moderate‐to‐severe pain after dental ...
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Remote ischemic preconditioning preceding coronary artery bypass grafting reduces the volume of ischemic brain lesions Abstract: Introduction: Neurological sequelae following cardiac surgery impact quality of life, mortality and health resource utilization. We hypothesized that remote ischemic preconditioning (RIPC) p...
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Ustekinumab treatment effectiveness in clinical practice-a multicentre retrospective review of long-term outcomes in Crohn's disease Abstract: Background: Recently published data demonstrated the efficacy of Ustekinumab (USK) in the treatment of moderate‐severe Crohn's disease. This study aimed to evaluate the Irish e...
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Inverse association between carbohydrate consumption and plasma adropin concentrations in humans Abstract: Objective: The role of metabolic condition and diet in regulating circulating levels of adropin, a peptide hormone linked to cardiometabolic control, is not well understood. In this study, weight loss and diet ef...
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Everolimus and early calcineurin inhibitor withdrawal is associated with superior renal function: 5-year follow-up of the randomized protect liver transplantation study Abstract: Purpose: At the end of the 12‐month (M) PROTECT core study (NCT00378014), de novo liver transplant recipients (LTxR) who switched from a cal...
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Cognitive-behavioral therapy and educational counseling for chronic pain and opioid dependence Abstract: Aims: To examine the efficacy of cognitive behavioral therapy (CBT) and educational counseling (EC)‐the educational component of CBT augmented by additional psychoeducation on chronic pain and addiction‐for co‐occu...
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Symptom clusters among MS-flash clinical trial participants Abstract: Objective: Women experience multiple co‐occurring symptoms (symptom clusters) during the menopausal transition and early postmenopause. Although symptom clusters have been identified among community‐dwelling populations, to date there have been no s...
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Rosiglitazone improves c-reactive protein and liver function in impaired glucose tolerance but not coronary artery calcification or exercise function Abstract: Type 2 diabetes (T2D) increases cardiovascular (CV) risk and decreases functional exercise capacity. We and others have reported that rosiglitazone (RO) improv...
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Comparison of the effects of terlipressin, somatostatin, and octreotide when combined with endoscopic treatment in acute gastroesophageal variceal bleeding: a multicenter prospective randomized controlled trial Abstract: Background and Aims: Vasoactive drugs, including terlipressin, somatostatin, and octreotide, are r...
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Physical therapy for persistent postpartum stress urinary incontinence: a seven year follow-up study Abstract: Hypothesis / aims of study The aim of this study was to evaluate the effect of intensive, eight‐week physical therapy programs, with and without deep abdominal muscle training, on persistent postpartum SUI se...
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Supraphysiologic Testosterone Increases Proactive Aggression in the Power-to-Take Game Abstract: Identifying the mechanisms that compel prosocial and antisocial behaviors is essential when seeking to develop effective social policies. While selfishness is ever present, in many situations cooperation is the norm. Testo...
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Clinical and radiographical performance of implants placed with simultaneous guided bone regeneration using resorbable and non-resorbable membranes after 22-24 years, a prospective, controlled clinical trial Abstract: AIM: The aim was to evaluate the performance of implants placed with simultaneous guided bone regener...
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A Comparative Study of Glycopyrollate and Ondansetron for the Control of Post Operative Nausea and Vomiting Following General Anaesthesia Abstract: Background : Postoperative nausea and vomiting (PONV) is a common distressing problem in patients undergoing surgery under general anaesthesia which requires frequent medi...
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More precise dosing of acenocoumarol for better control in patients aged above 80 years, a randomized controlled pilot study Abstract: Background: Many elderly patients are confined to treatment with vitamin K antagonists (VKA) instead of direct oral anticoagulants (DOACs). However, quality of VKA treatment declines w...
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Multifidis peripheral nerve stimulation randomized controlled trial Abstract: Introduction: ReActiv8‐B is an international, multicenter, prospective, randomized, sham‐controlled, blinded clinical trial with one‐way crossover, conducted under an IDE from the FDA (clinicaltrials. gov/show/NCT02577354). The study, perfor...
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Comparison of focal impulse and rotor modulation ablation (FIRM) only versus second-generation cyroballoon ablation in patients with paroxysmal atrial fibrillation Abstract: Background: Rotors have been postulated to be a major driver of atrial fibrillation (AF). Initial studies demonstrated, that focal impulse and ro...
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Forearm bone mineral density and fracture incidence in postmenopausal women with osteoporosis: results from the ACTIVE xtend phase 3 trial Abstract: Wrist fractures are the most common fracture of the upper extremity and are associated with increased subsequent fracture risk in women with postmenopausal osteoporosis. ...
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Nalbuphine pretreatment for prevention of etomidate induced myoclonus: a prospective, randomized and double-blind study Abstract: Background and Aims: Etomidate induced myoclonus (EM) is a common and hazardous sequel. Premedication with a number of opioids has been shown to effectively attenuate EM. However, there is ...
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Efficacy of autologous expanded bone marrow derived mesenchymal stem cells (AXBM-MSC) in the treatment of patients with Chron's disease who have failed to standard therapy: an open-label, randomized controlled clinical trial phase II Abstract: Crohn's disease is a severe and progressive auto inflammatory/autoimmune di...
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Double-blind, randomised, placebo-controlled three-way crossover clinical investigation to evaluate the beneft of IQP-VV-102 in reducing postprandial glucose level in overweight Caucasian subjects Abstract: Introduction: IQP‐VV‐102, which contains a proprietary grape extract (grape marc) and L‐arabinose, has been prov...
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Clearance of vancomycin-resistant Enterococcus concomitant with administration of a microbiota-based drug targeted at recurrent Clostridium difficile infection Abstract: Background. Vancomycin‐resistant Enterococcus (VRE) is a major healthcare‐associated pathogen and a well known complication among transplant and immu...
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Corneal collagen crosslinking and intracorneal ring segments: simultaneous vs sequential surgery Abstract: Purpose : Intacs® (implantable intracorneal ring segments (ICRS)) and corneal collagen crosslinking (CXL) are used for the treatment of keratoconus and corneal ectasia. In previous work, using symmetric 350μm seg...
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Stopping Tenofovir Disoproxil Fumarate (TDF) treatment after long term virologic suppression in HBeAg-negative CHB: week 48 interim results from an ongoing randomized, controlled trial (“FINITE CHB”) Abstract: Background and Aims: Long‐term effective NUC therapy may lead to partial restoration of HBV‐specific T cell f...
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Peroperative enteral nutrition with arginine-omega-3 fatty acids and ribonucleic acid and glutamin supplemented diet could improve postoperative recovery in lung cancer patients Abstract: Rationale: The purpose of this study was to evaluate the effect of peroperative immunonutrition pharmaceutics diet versus standard ...
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Social media and diabetes: can we improve glucose control in adolescents on pump therapy? One year experience Abstract: Background and aims: To evaluate results from social media (Skype and Facebook) and Carelink as tools to improve diabetes control in diabetic adolescents on Medtronic PRT (insulin pump with glucose s...
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Heralding cerebellar mutism: evidence for pre-surgical language impairment as primary risk factor in posterior fossa surgery Abstract: The aim of this study is to identify possible risks factors for the occurrence of cerebellar mutism syndrome (CMS) in children with posterior cranial fossa tumours. Children diagnosed ...
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The effect of antibiotic irrigation of surgical incisions in prevention of surgical site infection Abstract: Background: surgical site infection is one of the most common post operative complications alongside with sepsis, cardiovascular, pulmonary and thromboembolic complications. The development of surgical site inf...
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Effects of ruxolitinib cream on pruritus and sleep in atopic dermatitis: 52-week pooled results from two phase III studies Abstract: Atopic dermatitis (AD) is a highly pruritic, inflammatory skin disease. Quality of life can be significantly reduced by pruritus and sleep disturbances. Ruxolitinib cream is a topical fo...
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Cilostazol for Intermittent Claudication Abstract: Study design: A review of the Cochrane Vascular Specialized Register, CENTRAL, MEDLINE, Embase, CINAHL, and AMED databases, and the World Health Organization International Clinical Trials Registry Platform and trials registries on November 9, 2020. Key findings: Parti...
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Is It Realistic to Stop Prednisone in Early Rheumatoid Arthritis? A Subanalysis from the BeSt and IMPROVED Studies Abstract: Background/Purpose: Glucocorticoids are widely used in the treatment of rheumatoid arthritis (RA) patients. It is internationally recommended to taper and stop glucocorticoids as rapidly as clin...
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The effect of standard versus longer intestinal bypass on GLP-1 regulation and glucose metabolism in patients with type 2 diabetes undergoing Roux-en-Y gastric bypass Abstract: BACKGROUND: Roux‐en‐Y gastric bypass (RYGB) characteristically enhances post‐prandial levels of glucagon‐like peptide (GLP)‐1, a mechanism tha...
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Associations Between Parental Beliefs About Adolescence, Parent-Teen Communication, And Psychological Well-Being Abstract: Purpose: Prior research suggests that parental perceptions of adolescence as a period of ‘storm and stress’ are associated with more parent‐teen conflict, less involved parenting, and more problem...
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Extending the verifiability approach framework: the effect of initial questioning Abstract: The verifiability approach (VA) is a lie‐detection tool that examines reported checkable details. Across two studies, we attempt to exploit liar's preferred strategy of repeating information by examining the effect of questioni...
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A dual intervention in geriatric patients to prevent drug-related problems and improve discharge management Abstract: Background Drug‐related problems (DRPs) endanger geriatric patients' safety. Especially a follow‐up treatment with increased number of care transitions is a critical time for patients. Objective This s...
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Longitudinal intrinsic functional connectivity changes in preclinical Alzheimer's disease: a two-year follow up study Abstract: Background: Although previous cross sectional studies demonstrated intrinsic functional connectivity (FC) changes in the preclinical Alzheimer's disease (AD), effects of amyloid burden in FC ...
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Allergic rhinitis Abstract: Allergic rhinitis is one of the most common chronic diseases in childhood. The International Study of Asthma and Allergies in Childhood reported an average prevalence rhinitis of 8.5% among 6‐7‐year‐old children, and 14.6% for 13‐14 year‐old children1. The burden of allergic rhinitis to ind...
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Randomised controlled trial of avocado-soybean unsapomfiable (piascledine) effect on structure modification in hip osteoarthritis: the eradias study Abstract: Objective: To assess the ability of avocado‐soybean unsaponifiable‐ Expanscience (ASU‐E) to slow radiographic progression in symptomatic hip osteoarthritis (OA)...
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PCN7 Analysis of Individual-Level Association of Progression-Free Survival (PFS) and Time to Treatment Failure (TTF) with Overall Survival (OS) for Previously Untreated Advanced Renal Cell Carcinoma Patients in the CheckMate 214 Trial Abstract: Objectives: To determine the association between overall survival (OS) and...
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Early versus late sustained low efficiency dialysis in critically ill cirrhotics with septic shock and acute kidney injury-interim analysis of an open label randomized controlled trial-NCT02937961 Abstract: Background: Renal dialysis is a key to management of acute kidney injury (AKI) in the intensive care unit (ICU)....
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Sildenafil reduces pulmonary vascular resistance in single ventricular physiology Abstract: Background High pulmonary vascular resistance (PVR) may be a risk factor for early and late mortality in both Glen shunt and Fontan operation patients. Furthermore, PVR may increase long after the Fontan operation. Whether pulm...
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Effect of low dose rocuronium in preventing ventilation leak for flexible laryngeal mask airway during radical mastectomy Abstract: The flexible laryngeal mask airway (FLMA) is becoming more and more popular in general anesthesia during surgery of head, neck and upper chest. But very limited information has been publi...
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Vascular response to lipid-lowering therapy in diabetes versus non-diabetes patients: serial optical coherence tomography and intravascular ultrasound study Abstract: Background: Diabetes (DM) is a risk factor for recurrent ischemic events in patients with coronary artery disease. However, the difference in vascular r...
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Topical tranexamic acid as a promising treatment for melasma Abstract: Background: In recent times, tranexamic acid (TA) is claimed to have whitening effects especially for ultraviolet‐induced hyperpigmentation including melasma. The aim of our study was to evaluate the efficacy and safety of topical solution of TA an...
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Comparison with two types of training in dependent's elderly person Abstract: This study compared two types of training in 22 senior subjects of an EHPAD service. Subjects were randomized to either one of two groups, the "strength" or the "aerobic" group. Sixteen subjects participated to all sessions and were included...
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Efficacy and safety of balugrastim compared with pegfilgrastim in patients with breast cancer who are receiving chemotherapy Abstract: Background: Recombinant granulocyte colony‐stimulating factors (G‐CSFs) stimulate the proliferation and differentiation of neutrophils. Balugrastim is a long‐acting G‐CSF composed of a...
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Cognitive, neuroendocrine, and symptom change in PTSD treatment of OEF/OIF veterans Abstract: Background: While effective psychotherapies for the treatment of PTSD exist (Foa et al, 2008), the biological and cognitive mechanisms involved in effective treatment have received little empirical attention. The current stud...
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COMPUTER VISION MEASUREMENT OF DISEASE SEVERITY DISTRIBUTION OUTPERFORMS TRADITIONAL ENDOSCOPIC SCORING FOR DETECTING THERAPEUTIC RESPONSE IN A CLINICAL TRIAL OF USTEKINUMAB FOR ULCERATIVE COLITIS Abstract: BACKGROUND: Endoscopic scoring is a cornerstone of disease assessment in ulcerative colitis (UC). Novel computer...
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Impact of antibullying educational program on psychological adjustment among preparatory school victims Abstract: School bullying is a global problem confronting the international community that has been existed in public and private schools for years with a negative impact on the psychosocial wellbeing of victims tha...
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Umbralisib plus ublituximab (U2) is superior to obinutuzumab plus chlorambucil (O+Chl) in qqpatients with treatment-naïve (TN) and relapsed/ refractory (R/R) chronic lymphocytic leukemia (CLL): results from the phase 3 unity-CLL study Abstract: Background: Umbralisib is an oral, once‐daily, novel, kinase inhibitor of ...
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Controlled hypotension for FESS: a randomised double-blinded comparison of magnesium sulphate and dexmedetomidine Abstract: Background and Aims: Intense bleeding during general anaesthesia (GA) is the major limitation during functional endoscopic sinus surgery (FESS). This study was aimed to compare the efficacy of de...
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Development and validation of a novel scoring index (C-reactive protein, age, race, and tumor size) to predict renal functional decline post partial nephrectomy Abstract: Background: Functional decline is a sequelae of extirpative renal surgery with potential for significant morbidity. We utilized pre‐operative patien...
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Functional Status, Quality of Life and Ventricular Tachyarrhythmias Improve with Right Ventricular Pacing Compared to Biventricular Pacing in LVAD Patients Abstract: Purpose: Cardiac resynchronization therapy (CRT) and left ventricular assist devices (LVAD) independently improve outcomes in heart failure patients, but...
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A study of the effectiveness of group play therapy upon the theory of mind in preschool children Abstract: Theory of mind is a one of the most important issues of social cognition topics and whereas it is a prerequisite for understanding the social environment and involvement in social behavior competitive, it has bee...
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Effect of a bilberry extract (BILBERON®)-containing diet on the improvement of eye fatigue-related symptoms (II) - A randomized, double-blind, placebo-controlled, parallel-group comparison study Abstract: Objective: In recent years, it has been reported that the ingestion of bilberry extract improves visual function. ...
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Drug interactions in communitydwelling people screened positive for dementia: results of the DelpHi study Abstract: Background: Older people with polypharmacy run a higher risk of drug interactions. However, little is known about the prevalence of drug interactions in community‐dwelling people screened positive for de...
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Peanut-specific immunoglobulin levels following SCIT-treatment with a chemically modified, aluminum hydroxide adsorbed peanut extract (HALMPE1) in peanut allergic patients Abstract: Background: Currently, there is no effective disease modifying treatment for peanut allergy available. Therefore, a chemically modified, ...
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Determination of the most appropriate method for extrapolating overall survival data from a placebo-controlled clinical trial of lenvatinib for progressive, radioiodine-refractory differentiated thyroid cancer Abstract: Background: Cost‐effectiveness models for the treatment of long‐term conditions often require infor...
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Effects of therapeutic massage on metabolic control indicators in patients with type II diabetes Abstract: Objectives: Diabetes is a growing epidemic, resulting in significant mortality and morbidity. Individuals diagnosed with diabetes can improve their clinical outcomes through good metabolic control. Considering th...
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Bimatoprost 0.01% or 0.03% in patients with glaucoma or ocular hypertension previously treated with latanoprost: two randomized 12-week trials Abstract: Background: The purpose of this study was to evaluate the intraocular pressure (IOP)‐lowering efficacy and safety of bimatoprost 0.01% or 0.03% as monotherapy in pati...
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Prospective randomized controlled trial with crossover of endoscopic ultrasound fine needle aspiration (EUS-FNA) using 22g procore and 22g echotip needle for solid pancreatic mass: the “picore” study Abstract: Aim: To compare the diagnostic accuracy of EUS‐FNA between the novel22G Procore ™ (P) and the 22G EchoTip ® (...
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Immediate and delayed SWL for ureteral stones: late period success rates Abstract: OBJECTIVE: To investigate the effect on success rates after 3 SWL sessions of immediate or delayed SWL for ureteral stones. METHODS: Patients who applied with renal colic and who have single, radiopaque ureteric stone of 5 to 20mm size ...
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International phase III study of chlorambucil versus fludarabine as initial therapy for Waldenstrom macroglobulinaemia and related disorders Abstract: Waldenstrom macroglobulinaemia (WM) and related‐disorders (splenic marginal zone lymphoma: MZL, and non‐IgM lymphoplasmacytic lymphoma: LPL) are rare diseases with very...
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Health-Related Quality-of-Life Analysis From the Phase 3 CLEAR Trial of Lenvatinib + Pembrolizumab or Everolimus Versus Sunitinib for Patients With Advanced Renal Cell Carcinoma Abstract: INTRODUCTION AND OBJECTIVES: Lenvatinib + pembrolizumab (L+P) improved progression‐free survival, overall survival, and objective r...
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Feasibility of conducting a randomized, placebo-controlled study assessing whether omega-3 fatty acids prevent gout flares when starting urate-lowering treatment Abstract: OBJECTIVE: The aim was to test the feasibility of a randomized controlled trial exploring whether omega‐3 fatty acid supplementation limits gout fl...
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Additive effect of androgens and estrogens on pubertal growth acceleration Abstract: Objective: The influence of androgens and estrogens on growth is complex, and understanding their relative roles is important for optimizing the treatment of children with various disorders of growth and puberty. Design: We examined t...
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Role of radiotherapy and dose-densification of R-chop in primary mediastinal B-cell lymphoma: a subgroup analysis of the unfolder trial of the German lymphoma alliance (GLA) Abstract: Background: Primary mediastinal B‐cell lymphoma (PMBCL) is a distinct entity of aggressive lymphoma, which typically presents in young ...
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Derivation of “specific population who could benefit from Rosuvastatin”: a secondary analysis on randomised controlled trial to uncover novel value of Rosuvastatin for precise treatment of ARDS Abstract: Introduction: The high heterogeneity of ARDS contributes to paradoxical conclusions from previous investigations of...
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Axonal integrity in primary and secondary progressive multiple sclerosis: a baseline subgroup analysis of sex, age, and disease severity from the phase III SPI2 study Abstract: Objective: We used proton magnetic resonance spectroscopy (MRS) to measure potential differences in axonal integrity between primary and secon...
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An exploration of the shared experiences and personal impact of a progressive resistance training programme, for young people with cerebral palsy: a qualitative analysis Abstract: Introduction: While resistance training is often delivered as part of rehabilitation for young people with cerebral palsy (CP), little is k...
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A mixed-methods feasibility study exploring the cultural adaptation of walk with ease to the United Kingdom Abstract: Background/Purpose: The Arthritis Foundation's Walk With Ease (WWE) is an evidence‐based 6 week community‐based walking program for adults with arthritis delivered in instructor‐led or self‐directed fo...
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Long-term effect of elagolix on bone mineral density in women with endometriosis-associated pain Abstract: Introduction: To evaluate the long‐term effect of elagolix, an oral, non‐peptide GnRH antagonist, on bone mineral density (BMD) in two 6‐month (M) extension studies (Elaris EM‐III and IV) of the pivotal, 6M, phas...
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Prenatal use of aspirin and acetaminophen Abstract: INTRODUCTION: Acetaminophen is widely used in pregnancy for pain management. Recently published data indicates that in‐utero acetaminophen exposure may be associated with greater odds that the resulting child will develop ADHD. Aspirin may be a suitable alternative t...
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Deltamethrin resistance in Aedes aegypti results in treatment failure in Merida, Mexico Abstract: The operational impact of deltamethrin resistance on the efficacy of indoor insecticide applications to control Aedes aegypti was evaluated in Merida, Mexico. A randomized controlled trial quantified the efficacy of indoo...
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Clinical and electrophysiological correlates of absent somatosensory evoked potentials after post-anoxic brain damage: a multicentre cohort study Abstract: Introduction: Multimodal assessment is recommended for prognostication of coma after cardiac arrest (CA). Bilateral absence of cortical response (N20) to somatosen...
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Correction: FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-label phase 3 trial (The Lancet Oncology (2016) 17(10) (1426–1434) (S1470204516302698) (10.1016/S1470-2045(16)3...
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Results from phase 2 trial ongoing expansion stage of SL-401 in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) Abstract: Background: SL‐401 is a targeted therapy directed to the interleukin‐3 receptor (CD123), a target overexpressed on blastic plasmacytoid dendritic cell neoplasm (BPDCN) and other ...
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Efficacy of IPX066, an extended-release formulation of carbidopa-levodopa, in advanced Parkinson's disease patients with troublesome dyskinesia Abstract: Objective: Evaluate the efficacy of IPX066 in advanced Parkinson's disease (PD) patients with troublesome dyskinesia. Background: IPX066 is an extended‐release formu...
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Effectiveness of hepatitis C virus (HCV) testing for persons born during 1945-1965-summary results from three randomized controlled trials Abstract: PURPOSE: CDC and the U.S. Preventive Services Taskforce recommend 1‐time HCV testing for persons born during 1945‐1965 (birth cohort). We present summary results from 3 i...
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The risk of severe treatment-related adverse events is significantly lower in children compared with adults when treated with SQ-standardised grass allergy immunotherapy tablets: post hoc analysis of seven clinical trials Abstract: Background: Allergy immunotherapy tablets (AIT) is a safe and more convenient alternati...
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Long-term outcome of ligasure haemorrhoidectomy vs. Conventional diathermy for IV-degree haemorrhoids: a prospective randomized trial Abstract: Background Milligan‐Morgan operation is still considered the treatment of choice for IV‐degree haemorrhoids: it is frequently associated with significant postoperative pain an...
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AN EXPLORATORY COMBINED MACHINE LEARNING AND PHARMACOGENOMIC APPROACH TO PRECISION TREATMENT OF AUD WITH ZONISAMIDE Abstract: Purpose: We aimed to advance precision medicine by identifying a profile of likely responders (LRs) to zonisamide from clinical trial data using a combined machine learning and pharmacogenomic ...
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Brief systemic therapy in people exposed to a recent highly stressful event: a randomised controlled trial Abstract: Background: Highly stressful events can have harmful effects on people's well‐being and mental health. Objective: To evaluate the efficacy of a preventive intervention protocol based on Brief Systemic T...
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Immediate and Short-term Effects of Straw Phonation in Air or Water on Vocal Fold Vibration and Supraglottic Activity of Adult Patients with Voice Disorders Visualized with Strobovideolaryngoscopy: a Pilot Study Abstract: Purpose The first purpose of this study was to investigate and compare the short‐term effects aft...
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Effect of a postcard immunisation reminder in hospital outpatients: a randomised controlled trial Abstract: Background: Missed immunisation opportunities occur at hospital outpatient visits. The Australian Childhood Immunisation Register (ACIR) identifies children <7 years not up‐to‐date with routine immunisations, bu...
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Gonadotropin-releasing hormone agonist versus expectant management for treating multiple leiomyomas after myomectomy: the study protocol for a multicentre, prospective, randomised controlled clinical trial Abstract: Introduction Leiomyoma recurrence is a major concern for long‐term myomectomy management, especially fo...
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Integrated Chinese and western medicine for acute guillain-barré syndrome treatment Abstract: Guillain‐Barré syndrome (GBS) is a worldwide demyelinating polyradiculopathy and polyneuropathy. Currently, there is no specific drug for GBS, and established treatment is generally based on immune‐modulating treatment with p...
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Acceptability to parents of a baby-led approach to introducing solids Abstract: In Baby‐Led Weaning (BLW), infants are offered foods they can pick up and feed themselves from the start of complementary feeding. Infants who are fully BLW are not spoonfed at all by their parents, feeding themselves all their foods inste...
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Recruitment to the randomised iron deficiency anaemia management pilot (RAINDroP) Abstract: Introduction: The RAINDroP study is a pilot randomised clinical trial investigating the possible benefits of replacing oral iron therapy with intravenous iron in the treatment of iron deficiency anemia. One of the primary outco...
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Compressive strength of three all-ceramic chairside CAD/CAM onlays Abstract: BACKGROUND: The use of chairside computer aided design/computer aided manufacture (CAD/CAM) system is a convenient way to fabricate porcelain onlays that have been widely used in clinical practice. Different chairside CAD/CAM all‐ceramic mate...
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Comparing the effectiveness of sponge cooling and ice packs methods on controlling the patients’ fever in intensive care units: a randomized clinical trial Abstract: Introduction: Fever is a common problem in intensive care unit. Therefore, this study aimed to compare the effectiveness of two methods of sponge cooling...
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Decompression Surgery Alone Versus Decompression Plus Fusion in Symptomatic Lumbar Spinal Stenosis: a Swiss Prospective Multi-center Cohort Study with 3 Years of Follow-up Abstract: STUDY DESIGN.: Retrospective analysis of a prospective, multicenter cohort study. OBJECTIVE.: To estimate the added effect of surgical fu...
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Curative effect analysis of hepatoprotection by Jianganle particle combined with western medicine treatment on antituberculotic drug induced liver injury Abstract: Background: The research aimed to curative effect of hepatoprotection by Jianganle particle combined with diammonium glycyrrhizinate and tiopronin treatmen...
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The effect of testosterone therapyon muscle mass, bone mass and haemoglobin in hypogonadal men with cirrhosis Abstract: Background and Aims: Low testosterone and sarcopenia are common in men with cirrhosis and both are associated with adverse outcome. The effect of testosterone therapy on body composition has not prev...
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Evaluation of anesthesia profile in pediatric patients after inguinal hernia repair with caudal block or local wound infiltration Abstract: AIM: The aim of this study is to evaluate anesthesia and recovery profile in pediatric patients after inguinal hernia repair with caudal block or local wound infiltration. MATERIA...
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