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0 | Introduction. Depressive disorder is one of the most widespread forms of mental disorders which lead to a significant public health concern, such as disability, suicide, and so on. Its etiology remains vague but it is believed that depressive disorder is a multifactorial disease which is induced by the interaction of social, psychological, and biological factors. Thus, there is no clear and definite pathological theory could illustrate its mechanism independently until now, involving genetics, neuroimaging, neuroinflammation, neuroendocrine, and others. Comprehensive assessment to patients with depression is the starting point for a right diagnosis. History-taking of physical condition is as important as psychiatric interview and rational usage of scales would be beneficial for screening. There are many kinds of therapeutic measures for depressive patients nowadays, including general intervention, pharmacotherapy, psychotherapy, and physical therapy. For now, anti-depressants used in clinical practice is almost monoamine-based drugs while much more progress have been made in developing new antidepressant medications, like prototypical N-methyl-D-aspartate (NMDA) receptor antagonists, opioid agonists, gamma-aminobutyric acid (GABAA) receptors, and psychedelics. Once these novel drugs are proved to be practicable, it will create a historical evolution in the field of psychiatry. In addition, we advocate that measurement-based care (MBC) should run through the whole duration of treatment and goals of MBC in every stage are different. As brain projects in many countries are conducting in inspiring ways, we believe that our understanding about depressive disorder, of course, and other neuropsychiatric disorders will be better in the future. | [
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1 | Effects of different nose types on class II treatments for female patients. BACKGROUND: The aim of this study was to evaluate the effect of different nose types on the perception of facial aesthetics following camouflage treatment and orthognathic surgery for skeletal class II female patients.METHODS: A pre-treatment profile photograph of a skeletal class II adult patient was selected from the department archive. Two constructed photographs were created to represent orthognathic surgery and camouflage treatments with the aid of computer software. A total of 18 constructed images was composed using three profiles (pre-treatment, post-camouflage, and post-orthognathic surgery) and six nose types. These photographs were shown to the three groups (orthodontists, plastic surgeons, and lay people), and they were asked to assign an attractiveness score to each photo ranging from 0 to 100, with 0 indicating the least attractive and 100 indicating the most attractive.RESULTS: For the convex nose profiles, anterior movement of the mandible obtained by orthognathic surgery did not result in a significant change in the scores given by the lay people. When surgical or camouflage treatment was not implemented and, instead, just rhinoplasty was performed for these profiles, there was a significant increase in the aesthetic scores given by all groups. For the straight nose profiles, orthognathic surgery increased the attractiveness scores given by all groups. Furthermore, for all the profiles, extraction treatment did not affect the aesthetic scores given by any of the groups (P > 0.05).CONCLUSIONS: The lay people perceived that having a convex-bridged nose was a bigger problem than having a retrognathic profile. Overall, in terms of skeletal and dental orthodontic treatments, nose shape should be considered during the treatment planning process. | [
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2 | [Effect of moxibustion pretreatment at different time on ovarian function in rats with dimini-shed ovarian reserve]. OBJECTIVE: To observe the effect of moxibustion pretreatment at different time on serum hormone levels in diminished ovarian reserve (DOR) rats, so as to explore its protective mechanisms.METHODS: Forty female SD rats were randomly divided into control, model, moxibustion-1 (moxibustion was given 4 weeks before modeling), moxibustion-2 (moxibustion was given 2 weeks before modeling and 2 weeks from the 1st day on after modeling ) and moxibustion-3 (moxibustion was given 4 weeks from the 1st day on after modeling) groups (n=8 rats in each group). The DOR model was established by gavage of Tripterygium Glycosides (75 mg/kg) once daily for 14 days. Grain-moxibustion was applied to "Shenshu" (BL23) and "Guanyuan" (CV4) for 7 cones, 5 times a week for 4 weeks. The body weight and the ovary weight were recorded for calculating the ovarian index. The levels of serum anti-mullerian hormone (AMH), follicle stimulating hormone (FSH), estradiol (E2), androgen (T) and dehydroepiandrosterone (DHEA) were detected by ELISA.RESULTS: After modeling, ovarian index and serum AMH levels were obviously decreased (P<0.05), and the levels of serum FSH, E2, T and DHEA were significantly increased in contrast with the control group (P<0.05). Following intervention and compared with the model group, the serum FSH and DHEA levels of each moxibustion group were significantly reduced (P<0.05), the AMH levels significantly increased and E2 and T contents significantly decreased in the moxibustion-2 and moxibustion-3 groups (P<0.05). The serum FSH, E2 and T contents in moxibustion-2 group were obviously lower than those of the moxibustion-1 and moxibustion-3 groups (P<0.05).CONCLUSION: Moxibustion pre-treatment can improve ovarian reserve function in DOR rats, while the effect is different with different intervention time, and the best intervention time is pre-occurrence and early stage of DOR. | [
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3 | [Effect of electroacupuncture or moxibustion of "Tianshu" (ST25) on intragastric pressure in rats]. OBJECTIVE: To observe the effect of electroacupunctur (EA) and moxibustion of left or right "Tian-shu" (ST25) on intragastric pressure (IGP) in normal rats.METHODS: Twenty male SD rats were equally and randomly divided into EA group and moxibustion group. EA (2 Hz/15 Hz, 2 mA) or moxibustion (46-48 ?) was applied to unilate-ral ST25 for 2 min. The IGP was detected by using a pressure-transducer and an amplifier before and after EA or moxibustion.RESULTS: Compared with pre-intervention, the IGP was significantly decreased after EA or moxibustion stimulation of both left and right ST25 (P<0.05). The IGP levels during 0-30 s and 30-60 s of EA stimulation of both left and right ST25 were significantly lower than those of moxibustion (P<0.05). The IGP-lowering effect of EA on the left ST25 was evidently stronger than that of the right ST25 (P<0.05), but without significant difference between the bilateral sides in moxibustion-induced IGP reduction (P>0.05).CONCLUSION: Both EA and moxibustion of ST25 can lower IGP, and the effect of EA is significantly stronger than that of moxibustion in normal rats. In addition, the IGP-lowering effect of EA of the left ST25 is markedly stronger than that of the right ST25, suggesting a lateral advantage effect. | [
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4 | "[Analysis on the distribution of pressure- and heat-sensitive acupoints in patients with allergic r(...TRUNCATED) | [0.009605098515748978,0.0018664930248633027,0.030702760443091393,-0.05100349336862564,0.011492563411(...TRUNCATED) |
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7 | "[Effect of \"Yinqi Guiyuan\" needling on primary insomnia]. OBJECTIVE: To observe the clinical effe(...TRUNCATED) | [-0.010088800452649593,-0.026122039183974266,0.07736141979694366,-0.026122039183974266,0.05726754665(...TRUNCATED) |
8 | "[A modified device for transcutaneous electrical auricular concha stimulation in rats]. In the pres(...TRUNCATED) | [0.026033805683255196,0.00671572657302022,0.07130277901887894,-0.0033993185497820377,-0.000829102064(...TRUNCATED) |
9 | "Experimental transmission of infectious spleen and kidney necrosis virus (ISKNV) from freshwater or(...TRUNCATED) | [-0.008745511993765831,0.016884898766875267,0.009308341890573502,-0.034808866679668427,0.04277507588(...TRUNCATED) |
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BioASQ-BEIR Vector Database Dataset (2048d, 100k)
Generated embeddings dataset for vector database training and evaluation.
Dataset Summary
This dataset contains 100,000 text samples with vector embeddings (2048 dimensions) generated from the BioASQ-BEIR dataset using Qwen/Qwen3-Embedding-8B.
Dataset Structure
- Base dataset: 100,000 samples with embeddings
- Embedding dimension: 2048
Repository Structure
parquet/
base.parquet- Main dataset with text and embeddings
Usage
Loading with HuggingFace Datasets
from datasets import load_dataset
dataset = load_dataset("maknee/bioasq_bier_2048_100k")
base_data = dataset['train']
import numpy as np
embeddings = np.array(base_data['embedding'])
texts = base_data['text']
Dataset Information
- Source: BioASQ-BEIR
- Size: 100,000 samples
- Dimension: 2048
- Format: Parquet
Citation
@dataset{huggingface_embeddings_maknee_bioasq_bier_2048_100k,
title={BioASQ-BEIR Vector Database Embeddings Dataset},
author={Henry Zhu},
year={2026},
url={https://huggingface.co/datasets/maknee/bioasq_bier_2048_100k}
}
License
MIT License.
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