idx
int64
0
63k
question
stringlengths
53
5.28k
target
stringlengths
5
805
17,500
def save ( self , model_fname = 'model.pkl' ) : with open ( model_fname , 'wb' ) as fh : pickle . dump ( self . stmts , fh , protocol = 4 )
Save the state of the IncrementalModel in a pickle file .
17,501
def add_statements ( self , pmid , stmts ) : if pmid not in self . stmts : self . stmts [ pmid ] = stmts else : self . stmts [ pmid ] += stmts
Add INDRA Statements to the incremental model indexed by PMID .
17,502
def preassemble ( self , filters = None , grounding_map = None ) : stmts = self . get_statements ( ) stmts = ac . filter_no_hypothesis ( stmts ) if grounding_map is not None : stmts = ac . map_grounding ( stmts , grounding_map = grounding_map ) else : stmts = ac . map_grounding ( stmts ) if filters and ( 'grounding' in...
Preassemble the Statements collected in the model .
17,503
def get_model_agents ( self ) : model_stmts = self . get_statements ( ) agents = [ ] for stmt in model_stmts : for a in stmt . agent_list ( ) : if a is not None : agents . append ( a ) return agents
Return a list of all Agents from all Statements .
17,504
def get_statements ( self ) : stmt_lists = [ v for k , v in self . stmts . items ( ) ] stmts = [ ] for s in stmt_lists : stmts += s return stmts
Return a list of all Statements in a single list .
17,505
def get_statements_noprior ( self ) : stmt_lists = [ v for k , v in self . stmts . items ( ) if k != 'prior' ] stmts = [ ] for s in stmt_lists : stmts += s return stmts
Return a list of all non - prior Statements in a single list .
17,506
def process_ndex_neighborhood ( gene_names , network_id = None , rdf_out = 'bel_output.rdf' , print_output = True ) : logger . warning ( 'This method is deprecated and the results are not ' 'guaranteed to be correct. Please use ' 'process_pybel_neighborhood instead.' ) if network_id is None : network_id = '9ea3c170-01a...
Return a BelRdfProcessor for an NDEx network neighborhood .
17,507
def process_pybel_neighborhood ( gene_names , network_file = None , network_type = 'belscript' , ** kwargs ) : if network_file is None : network_file = os . path . join ( os . path . dirname ( os . path . abspath ( __file__ ) ) , os . path . pardir , os . path . pardir , os . path . pardir , 'data' , 'large_corpus.bel'...
Return PybelProcessor around neighborhood of given genes in a network .
17,508
def process_pybel_graph ( graph ) : bp = PybelProcessor ( graph ) bp . get_statements ( ) if bp . annot_manager . failures : logger . warning ( 'missing %d annotation pairs' , sum ( len ( v ) for v in bp . annot_manager . failures . values ( ) ) ) return bp
Return a PybelProcessor by processing a PyBEL graph .
17,509
def process_belscript ( file_name , ** kwargs ) : if 'citation_clearing' not in kwargs : kwargs [ 'citation_clearing' ] = False if 'no_identifier_validation' not in kwargs : kwargs [ 'no_identifier_validation' ] = True pybel_graph = pybel . from_path ( file_name , ** kwargs ) return process_pybel_graph ( pybel_graph )
Return a PybelProcessor by processing a BEL script file .
17,510
def process_json_file ( file_name ) : with open ( file_name , 'rt' ) as fh : pybel_graph = pybel . from_json_file ( fh , False ) return process_pybel_graph ( pybel_graph )
Return a PybelProcessor by processing a Node - Link JSON file .
17,511
def process_cbn_jgif_file ( file_name ) : with open ( file_name , 'r' ) as jgf : return process_pybel_graph ( pybel . from_cbn_jgif ( json . load ( jgf ) ) )
Return a PybelProcessor by processing a CBN JGIF JSON file .
17,512
def update_famplex ( ) : famplex_url_pattern = 'https://raw.githubusercontent.com/sorgerlab/famplex/master/%s.csv' csv_names = [ 'entities' , 'equivalences' , 'gene_prefixes' , 'grounding_map' , 'relations' ] for csv_name in csv_names : url = famplex_url_pattern % csv_name save_from_http ( url , os . path . join ( path...
Update all the CSV files that form the FamPlex resource .
17,513
def update_lincs_small_molecules ( ) : url = 'http://lincs.hms.harvard.edu/db/sm/' sm_data = load_lincs_csv ( url ) sm_dict = { d [ 'HMS LINCS ID' ] : d . copy ( ) for d in sm_data } assert len ( sm_dict ) == len ( sm_data ) , "We lost data." fname = os . path . join ( path , 'lincs_small_molecules.json' ) with open ( ...
Load the csv of LINCS small molecule metadata into a dict .
17,514
def update_lincs_proteins ( ) : url = 'http://lincs.hms.harvard.edu/db/proteins/' prot_data = load_lincs_csv ( url ) prot_dict = { d [ 'HMS LINCS ID' ] : d . copy ( ) for d in prot_data } assert len ( prot_dict ) == len ( prot_data ) , "We lost data." fname = os . path . join ( path , 'lincs_proteins.json' ) with open ...
Load the csv of LINCS protein metadata into a dict .
17,515
def _get_is_direct ( stmt ) : any_indirect = False for ev in stmt . evidence : if ev . epistemics . get ( 'direct' ) is True : return True elif ev . epistemics . get ( 'direct' ) is False : any_indirect = True if any_indirect : return False return True
Returns true if there is evidence that the statement is a direct interaction . If any of the evidences associated with the statement indicates a direct interatcion then we assume the interaction is direct . If there is no evidence for the interaction being indirect then we default to direct .
17,516
def make_model ( self ) : for stmt in self . statements : if isinstance ( stmt , Modification ) : card = assemble_modification ( stmt ) elif isinstance ( stmt , SelfModification ) : card = assemble_selfmodification ( stmt ) elif isinstance ( stmt , Complex ) : card = assemble_complex ( stmt ) elif isinstance ( stmt , T...
Assemble statements into index cards .
17,517
def print_model ( self ) : cards = [ c . card for c in self . cards ] if len ( cards ) == 1 : cards = cards [ 0 ] cards_json = json . dumps ( cards , indent = 1 ) return cards_json
Return the assembled cards as a JSON string .
17,518
def geneways_action_to_indra_statement_type ( actiontype , plo ) : actiontype = actiontype . lower ( ) statement_generator = None is_direct = ( plo == 'P' ) if actiontype == 'bind' : statement_generator = lambda substance1 , substance2 , evidence : Complex ( [ substance1 , substance2 ] , evidence = evidence ) is_direct...
Return INDRA Statement corresponding to Geneways action type .
17,519
def make_statement ( self , action , mention ) : ( statement_generator , is_direct ) = geneways_action_to_indra_statement_type ( mention . actiontype , action . plo ) if statement_generator is None : return None text = None if self . get_ft_mention : try : content , content_type = get_full_text ( mention . pmid , 'pmid...
Makes an INDRA statement from a Geneways action and action mention .
17,520
def load_from_rdf_file ( self , rdf_file ) : self . graph = rdflib . Graph ( ) self . graph . parse ( os . path . abspath ( rdf_file ) , format = 'nt' ) self . initialize ( )
Initialize given an RDF input file representing the hierarchy .
17,521
def load_from_rdf_string ( self , rdf_str ) : self . graph = rdflib . Graph ( ) self . graph . parse ( data = rdf_str , format = 'nt' ) self . initialize ( )
Initialize given an RDF string representing the hierarchy .
17,522
def extend_with ( self , rdf_file ) : self . graph . parse ( os . path . abspath ( rdf_file ) , format = 'nt' ) self . initialize ( )
Extend the RDF graph of this HierarchyManager with another RDF file .
17,523
def build_transitive_closures ( self ) : self . component_counter = 0 for rel , tc_dict in ( ( self . isa_objects , self . isa_closure ) , ( self . partof_objects , self . partof_closure ) , ( self . isa_or_partof_objects , self . isa_or_partof_closure ) ) : self . build_transitive_closure ( rel , tc_dict )
Build the transitive closures of the hierarchy .
17,524
def build_transitive_closure ( self , rel , tc_dict ) : rel_fun = lambda node , graph : rel ( node ) for x in self . graph . all_nodes ( ) : rel_closure = self . graph . transitiveClosure ( rel_fun , x ) xs = x . toPython ( ) for y in rel_closure : ys = y . toPython ( ) if xs == ys : continue try : tc_dict [ xs ] . app...
Build a transitive closure for a given relation in a given dict .
17,525
def directly_or_indirectly_related ( self , ns1 , id1 , ns2 , id2 , closure_dict , relation_func ) : if id2 is None or ( id2 is None and id1 is None ) : return True elif id1 is None : return False if closure_dict : term1 = self . get_uri ( ns1 , id1 ) term2 = self . get_uri ( ns2 , id2 ) ec = closure_dict . get ( term1...
Return True if two entities have the speicified relationship .
17,526
def isa ( self , ns1 , id1 , ns2 , id2 ) : rel_fun = lambda node , graph : self . isa_objects ( node ) return self . directly_or_indirectly_related ( ns1 , id1 , ns2 , id2 , self . isa_closure , rel_fun )
Return True if one entity has an isa relationship to another .
17,527
def partof ( self , ns1 , id1 , ns2 , id2 ) : rel_fun = lambda node , graph : self . partof_objects ( node ) return self . directly_or_indirectly_related ( ns1 , id1 , ns2 , id2 , self . partof_closure , rel_fun )
Return True if one entity is partof another .
17,528
def isa_or_partof ( self , ns1 , id1 , ns2 , id2 ) : rel_fun = lambda node , graph : self . isa_or_partof_objects ( node ) return self . directly_or_indirectly_related ( ns1 , id1 , ns2 , id2 , self . isa_or_partof_closure , rel_fun )
Return True if two entities are in an isa or partof relationship
17,529
def is_opposite ( self , ns1 , id1 , ns2 , id2 ) : u1 = self . get_uri ( ns1 , id1 ) u2 = self . get_uri ( ns2 , id2 ) t1 = rdflib . term . URIRef ( u1 ) t2 = rdflib . term . URIRef ( u2 ) rel = rdflib . term . URIRef ( self . relations_prefix + 'is_opposite' ) to = self . graph . objects ( t1 , rel ) if t2 in to : ret...
Return True if two entities are in an is_opposite relationship
17,530
def get_parents ( self , uri , type = 'all' ) : all_parents = set ( self . isa_or_partof_closure . get ( uri , [ ] ) ) if not all_parents or type == 'all' : return all_parents if type == 'immediate' : node = rdflib . term . URIRef ( uri ) immediate_parents = list ( set ( self . isa_or_partof_objects ( node ) ) ) return...
Return parents of a given entry .
17,531
def _get_perf ( text , msg_id ) : msg = KQMLPerformative ( 'REQUEST' ) msg . set ( 'receiver' , 'READER' ) content = KQMLList ( 'run-text' ) content . sets ( 'text' , text ) msg . set ( 'content' , content ) msg . set ( 'reply-with' , msg_id ) return msg
Return a request message for a given text .
17,532
def read_pmc ( self , pmcid ) : msg = KQMLPerformative ( 'REQUEST' ) msg . set ( 'receiver' , 'READER' ) content = KQMLList ( 'run-pmcid' ) content . sets ( 'pmcid' , pmcid ) content . set ( 'reply-when-done' , 'true' ) msg . set ( 'content' , content ) msg . set ( 'reply-with' , 'P-%s' % pmcid ) self . reply_counter +...
Read a given PMC article .
17,533
def read_text ( self , text ) : logger . info ( 'Reading: "%s"' % text ) msg_id = 'RT000%s' % self . msg_counter kqml_perf = _get_perf ( text , msg_id ) self . reply_counter += 1 self . msg_counter += 1 self . send ( kqml_perf )
Read a given text phrase .
17,534
def receive_reply ( self , msg , content ) : reply_head = content . head ( ) if reply_head == 'error' : comment = content . gets ( 'comment' ) logger . error ( 'Got error reply: "%s"' % comment ) else : extractions = content . gets ( 'ekb' ) self . extractions . append ( extractions ) self . reply_counter -= 1 if self ...
Handle replies with reading results .
17,535
def split_long_sentence ( sentence , words_per_line ) : words = sentence . split ( ' ' ) split_sentence = '' for i in range ( len ( words ) ) : split_sentence = split_sentence + words [ i ] if ( i + 1 ) % words_per_line == 0 : split_sentence = split_sentence + '\n' elif i != len ( words ) - 1 : split_sentence = split_s...
Takes a sentence and adds a newline every words_per_line words .
17,536
def shorter_name ( key ) : key_short = key for sep in [ '#' , '/' ] : ind = key_short . rfind ( sep ) if ind is not None : key_short = key_short [ ind + 1 : ] else : key_short = key_short return key_short . replace ( '-' , '_' ) . replace ( '.' , '_' )
Return a shorter name for an id .
17,537
def add_event_property_edges ( event_entity , entries ) : do_not_log = [ '@type' , '@id' , 'http://worldmodelers.com/DataProvenance#sourced_from' ] for prop in event_entity : if prop not in do_not_log : value = event_entity [ prop ] value_entry = None value_str = None if '@id' in value [ 0 ] : value = value [ 0 ] [ '@i...
Adds edges to the graph for event properties .
17,538
def get_sourced_from ( entry ) : sourced_from = 'http://worldmodelers.com/DataProvenance#sourced_from' if sourced_from in entry : values = entry [ sourced_from ] values = [ i [ '@id' ] for i in values ] return values
Get a list of values from the source_from attribute
17,539
def get_entry_compact_text_repr ( entry , entries ) : text = get_shortest_text_value ( entry ) if text is not None : return text else : sources = get_sourced_from ( entry ) if sources is not None : texts = [ ] for source in sources : source_entry = entries [ source ] texts . append ( get_shortest_text_value ( source_en...
If the entry has a text value return that . If the entry has a source_from value return the text value of the source . Otherwise return None .
17,540
def process_text ( text , output_fmt = 'json' , outbuf = None , cleanup = True , key = '' , ** kwargs ) : nxml_str = make_nxml_from_text ( text ) return process_nxml_str ( nxml_str , output_fmt , outbuf , cleanup , key , ** kwargs )
Return processor with Statements extracted by reading text with Sparser .
17,541
def process_nxml_str ( nxml_str , output_fmt = 'json' , outbuf = None , cleanup = True , key = '' , ** kwargs ) : tmp_fname = 'PMC%s_%d.nxml' % ( key , mp . current_process ( ) . pid ) with open ( tmp_fname , 'wb' ) as fh : fh . write ( nxml_str . encode ( 'utf-8' ) ) try : sp = process_nxml_file ( tmp_fname , output_f...
Return processor with Statements extracted by reading an NXML string .
17,542
def process_nxml_file ( fname , output_fmt = 'json' , outbuf = None , cleanup = True , ** kwargs ) : sp = None out_fname = None try : out_fname = run_sparser ( fname , output_fmt , outbuf , ** kwargs ) sp = process_sparser_output ( out_fname , output_fmt ) except Exception as e : logger . error ( "Sparser failed to run...
Return processor with Statements extracted by reading an NXML file .
17,543
def process_sparser_output ( output_fname , output_fmt = 'json' ) : if output_fmt not in [ 'json' , 'xml' ] : logger . error ( "Unrecognized output format '%s'." % output_fmt ) return None sp = None with open ( output_fname , 'rt' ) as fh : if output_fmt == 'json' : json_dict = json . load ( fh ) sp = process_json_dict...
Return a processor with Statements extracted from Sparser XML or JSON
17,544
def process_xml ( xml_str ) : try : tree = ET . XML ( xml_str , parser = UTB ( ) ) except ET . ParseError as e : logger . error ( 'Could not parse XML string' ) logger . error ( e ) return None sp = _process_elementtree ( tree ) return sp
Return processor with Statements extracted from a Sparser XML .
17,545
def run_sparser ( fname , output_fmt , outbuf = None , timeout = 600 ) : if not sparser_path or not os . path . exists ( sparser_path ) : logger . error ( 'Sparser executable not set in %s' % sparser_path_var ) return None if output_fmt == 'xml' : format_flag = '-x' suffix = '.xml' elif output_fmt == 'json' : format_fl...
Return the path to reading output after running Sparser reading .
17,546
def get_version ( ) : assert sparser_path is not None , "Sparser path is not defined." with open ( os . path . join ( sparser_path , 'version.txt' ) , 'r' ) as f : version = f . read ( ) . strip ( ) return version
Return the version of the Sparser executable on the path .
17,547
def make_nxml_from_text ( text ) : text = _escape_xml ( text ) header = '<?xml version="1.0" encoding="UTF-8" ?>' + '<OAI-PMH><article><body><sec id="s1"><p>' footer = '</p></sec></body></article></OAI-PMH>' nxml_str = header + text + footer return nxml_str
Return raw text wrapped in NXML structure .
17,548
def get_hgnc_name ( hgnc_id ) : try : hgnc_name = hgnc_names [ hgnc_id ] except KeyError : xml_tree = get_hgnc_entry ( hgnc_id ) if xml_tree is None : return None hgnc_name_tag = xml_tree . find ( "result/doc/str[@name='symbol']" ) if hgnc_name_tag is None : return None hgnc_name = hgnc_name_tag . text . strip ( ) retu...
Return the HGNC symbol corresponding to the given HGNC ID .
17,549
def get_hgnc_entry ( hgnc_id ) : url = hgnc_url + 'hgnc_id/%s' % hgnc_id headers = { 'Accept' : '*/*' } res = requests . get ( url , headers = headers ) if not res . status_code == 200 : return None xml_tree = ET . XML ( res . content , parser = UTB ( ) ) return xml_tree
Return the HGNC entry for the given HGNC ID from the web service .
17,550
def analyze_reach_log ( log_fname = None , log_str = None ) : assert bool ( log_fname ) ^ bool ( log_str ) , 'Must specify log_fname OR log_str' started_patt = re . compile ( 'Starting ([\d]+)' ) finished_patt = re . compile ( 'Finished ([\d]+)' ) def get_content_nums ( txt ) : pat = 'Retrieved content for ([\d]+) / ([...
Return unifinished PMIDs given a log file name .
17,551
def get_logs_from_db_reading ( job_prefix , reading_queue = 'run_db_reading_queue' ) : s3 = boto3 . client ( 's3' ) gen_prefix = 'reading_results/%s/logs/%s' % ( job_prefix , reading_queue ) job_log_data = s3 . list_objects_v2 ( Bucket = 'bigmech' , Prefix = join ( gen_prefix , job_prefix ) ) log_strs = [ ] for fdict i...
Get the logs stashed on s3 for a particular reading .
17,552
def separate_reach_logs ( log_str ) : log_lines = log_str . splitlines ( ) reach_logs = [ ] reach_lines = [ ] adding_reach_lines = False for l in log_lines [ : ] : if not adding_reach_lines and 'Beginning reach' in l : adding_reach_lines = True elif adding_reach_lines and 'Reach finished' in l : adding_reach_lines = Fa...
Get the list of reach logs from the overall logs .
17,553
def get_unyielding_tcids ( log_str ) : tcid_strs = re . findall ( 'INFO: \[.*?\].*? - Got no statements for (\d+).*' , log_str ) return { int ( tcid_str ) for tcid_str in tcid_strs }
Extract the set of tcids for which no statements were created .
17,554
def analyze_db_reading ( job_prefix , reading_queue = 'run_db_reading_queue' ) : log_strs = get_logs_from_db_reading ( job_prefix , reading_queue ) indra_log_strs = [ ] all_reach_logs = [ ] log_stats = [ ] for log_str in log_strs : log_str , reach_logs = separate_reach_logs ( log_str ) all_reach_logs . extend ( reach_l...
Run various analysis on a particular reading job .
17,555
def process_pc_neighborhood ( gene_names , neighbor_limit = 1 , database_filter = None ) : model = pcc . graph_query ( 'neighborhood' , gene_names , neighbor_limit = neighbor_limit , database_filter = database_filter ) if model is not None : return process_model ( model )
Returns a BiopaxProcessor for a PathwayCommons neighborhood query .
17,556
def process_pc_pathsbetween ( gene_names , neighbor_limit = 1 , database_filter = None , block_size = None ) : if not block_size : model = pcc . graph_query ( 'pathsbetween' , gene_names , neighbor_limit = neighbor_limit , database_filter = database_filter ) if model is not None : return process_model ( model ) else : ...
Returns a BiopaxProcessor for a PathwayCommons paths - between query .
17,557
def process_pc_pathsfromto ( source_genes , target_genes , neighbor_limit = 1 , database_filter = None ) : model = pcc . graph_query ( 'pathsfromto' , source_genes , target_genes , neighbor_limit = neighbor_limit , database_filter = database_filter ) if model is not None : return process_model ( model )
Returns a BiopaxProcessor for a PathwayCommons paths - from - to query .
17,558
def process_model ( model ) : bp = BiopaxProcessor ( model ) bp . get_modifications ( ) bp . get_regulate_activities ( ) bp . get_regulate_amounts ( ) bp . get_activity_modification ( ) bp . get_gef ( ) bp . get_gap ( ) bp . get_conversions ( ) bp . eliminate_exact_duplicates ( ) return bp
Returns a BiopaxProcessor for a BioPAX model object .
17,559
def is_background_knowledge ( stmt ) : any_background = False for ev in stmt . evidence : epi = ev . epistemics if epi is not None : sec = epi . get ( 'section_type' ) if sec is not None and sec not in background_secs : return False elif sec in background_secs : any_background = True return any_background
Return True if Statement is only supported by background knowledge .
17,560
def multiple_sources ( stmt ) : sources = list ( set ( [ e . source_api for e in stmt . evidence ] ) ) if len ( sources ) > 1 : return True return False
Return True if statement is supported by multiple sources .
17,561
def id_to_symbol ( self , entrez_id ) : entrez_id = str ( entrez_id ) if entrez_id not in self . ids_to_symbols : m = 'Could not look up symbol for Entrez ID ' + entrez_id raise Exception ( m ) return self . ids_to_symbols [ entrez_id ]
Gives the symbol for a given entrez id )
17,562
def make_model ( self , output_file , add_curation_cols = False , up_only = False ) : stmt_header = [ 'INDEX' , 'UUID' , 'TYPE' , 'STR' , 'AG_A_TEXT' , 'AG_A_LINKS' , 'AG_A_STR' , 'AG_B_TEXT' , 'AG_B_LINKS' , 'AG_B_STR' , 'PMID' , 'TEXT' , 'IS_HYP' , 'IS_DIRECT' ] if add_curation_cols : stmt_header = stmt_header + [ 'A...
Export the statements into a tab - separated text file .
17,563
def get_create_base_agent ( self , agent ) : try : base_agent = self . agents [ _n ( agent . name ) ] except KeyError : base_agent = BaseAgent ( _n ( agent . name ) ) self . agents [ _n ( agent . name ) ] = base_agent if isinstance ( agent , Agent ) : for bc in agent . bound_conditions : bound_base_agent = self . get_c...
Return base agent with given name creating it if needed .
17,564
def create_site ( self , site , states = None ) : if site not in self . sites : self . sites . append ( site ) if states is not None : self . site_states . setdefault ( site , [ ] ) try : states = list ( states ) except TypeError : return self . add_site_states ( site , states )
Create a new site on an agent if it doesn t already exist .
17,565
def create_mod_site ( self , mc ) : site_name = get_mod_site_name ( mc ) ( unmod_site_state , mod_site_state ) = states [ mc . mod_type ] self . create_site ( site_name , ( unmod_site_state , mod_site_state ) ) site_anns = [ Annotation ( ( site_name , mod_site_state ) , mc . mod_type , 'is_modification' ) ] if mc . res...
Create modification site for the BaseAgent from a ModCondition .
17,566
def add_site_states ( self , site , states ) : for state in states : if state not in self . site_states [ site ] : self . site_states [ site ] . append ( state )
Create new states on an agent site if the state doesn t exist .
17,567
def add_activity_form ( self , activity_pattern , is_active ) : if is_active : if activity_pattern not in self . active_forms : self . active_forms . append ( activity_pattern ) else : if activity_pattern not in self . inactive_forms : self . inactive_forms . append ( activity_pattern )
Adds the pattern as an active or inactive form to an Agent .
17,568
def add_activity_type ( self , activity_type ) : if activity_type not in self . activity_types : self . activity_types . append ( activity_type )
Adds an activity type to an Agent .
17,569
def make_annotation ( self ) : annotation = dict ( ) for item in dir ( self ) : if len ( item ) > 0 and item [ 0 ] != '_' and not inspect . ismethod ( getattr ( self , item ) ) : annotation [ item ] = getattr ( self , item ) annotation [ 'action_mentions' ] = list ( ) for action_mention in self . action_mentions : anno...
Returns a dictionary with all properties of the action and each of its action mentions .
17,570
def _search_path ( self , directory_name , filename ) : full_path = path . join ( directory_name , filename ) if path . exists ( full_path ) : return full_path return None
Searches for a given file in the specified directory .
17,571
def _init_action_list ( self , action_filename ) : self . actions = list ( ) self . hiid_to_action_index = dict ( ) f = codecs . open ( action_filename , 'r' , encoding = 'latin-1' ) first_line = True for line in f : line = line . rstrip ( ) if first_line : first_line = False else : self . actions . append ( GenewaysAc...
Parses the file and populates the data .
17,572
def _link_to_action_mentions ( self , actionmention_filename ) : parser = GenewaysActionMentionParser ( actionmention_filename ) self . action_mentions = parser . action_mentions for action_mention in self . action_mentions : hiid = action_mention . hiid if hiid not in self . hiid_to_action_index : m1 = 'Parsed action ...
Add action mentions
17,573
def _lookup_symbols ( self , symbols_filename ) : symbol_lookup = GenewaysSymbols ( symbols_filename ) for action in self . actions : action . up_symbol = symbol_lookup . id_to_symbol ( action . up ) action . dn_symbol = symbol_lookup . id_to_symbol ( action . dn )
Look up symbols for actions and action mentions
17,574
def get_top_n_action_types ( self , top_n ) : action_type_to_counts = dict ( ) for action in self . actions : actiontype = action . actiontype if actiontype not in action_type_to_counts : action_type_to_counts [ actiontype ] = 1 else : action_type_to_counts [ actiontype ] = action_type_to_counts [ actiontype ] + 1 acti...
Returns the top N actions by count .
17,575
def get_string ( self ) : graph_string = self . graph . to_string ( ) graph_string = graph_string . replace ( '\\N' , '\\n' ) return graph_string
Return the assembled graph as a string .
17,576
def save_dot ( self , file_name = 'graph.dot' ) : s = self . get_string ( ) with open ( file_name , 'wt' ) as fh : fh . write ( s )
Save the graph in a graphviz dot file .
17,577
def save_pdf ( self , file_name = 'graph.pdf' , prog = 'dot' ) : self . graph . draw ( file_name , prog = prog )
Draw the graph and save as an image or pdf file .
17,578
def _add_edge ( self , source , target , ** kwargs ) : edge_properties = self . edge_properties for k , v in kwargs . items ( ) : edge_properties [ k ] = v self . graph . add_edge ( source , target , ** edge_properties )
Add an edge to the graph .
17,579
def _add_node ( self , agent ) : if agent is None : return node_label = _get_node_label ( agent ) if isinstance ( agent , Agent ) and agent . bound_conditions : bound_agents = [ bc . agent for bc in agent . bound_conditions if bc . is_bound ] if bound_agents : bound_names = [ _get_node_label ( a ) for a in bound_agents...
Add an Agent as a node to the graph .
17,580
def _add_stmt_edge ( self , stmt ) : source = _get_node_key ( stmt . agent_list ( ) [ 0 ] ) target = _get_node_key ( stmt . agent_list ( ) [ 1 ] ) edge_key = ( source , target , stmt . __class__ . __name__ ) if edge_key in self . existing_edges : return self . existing_edges . append ( edge_key ) if isinstance ( stmt ,...
Assemble a Modification statement .
17,581
def _add_complex ( self , members , is_association = False ) : params = { 'color' : '#0000ff' , 'arrowhead' : 'dot' , 'arrowtail' : 'dot' , 'dir' : 'both' } for m1 , m2 in itertools . combinations ( members , 2 ) : if self . _has_complex_node ( m1 , m2 ) : continue if is_association : m1_key = _get_node_key ( m1 . conc...
Assemble a Complex statement .
17,582
def process_from_file ( signor_data_file , signor_complexes_file = None ) : data_iter = read_unicode_csv ( signor_data_file , delimiter = ';' , skiprows = 1 ) complexes_iter = None if signor_complexes_file : complexes_iter = read_unicode_csv ( signor_complexes_file , delimiter = ';' , skiprows = 1 ) else : logger . war...
Process Signor interaction data from CSV files .
17,583
def _handle_response ( res , delimiter ) : if res . status_code == 200 : if sys . version_info [ 0 ] < 3 : csv_io = BytesIO ( res . content ) else : csv_io = StringIO ( res . text ) data_iter = read_unicode_csv_fileobj ( csv_io , delimiter = delimiter , skiprows = 1 ) else : raise Exception ( 'Could not download Signor...
Get an iterator over the CSV data from the response .
17,584
def get_protein_expression ( gene_names , cell_types ) : A = 0.2438361 B = 3.0957627 mrna_amounts = cbio_client . get_ccle_mrna ( gene_names , cell_types ) protein_amounts = copy ( mrna_amounts ) for cell_type in cell_types : amounts = mrna_amounts . get ( cell_type ) if amounts is None : continue for gene_name , amoun...
Return the protein expression levels of genes in cell types .
17,585
def get_aspect ( cx , aspect_name ) : if isinstance ( cx , dict ) : return cx . get ( aspect_name ) for entry in cx : if list ( entry . keys ( ) ) [ 0 ] == aspect_name : return entry [ aspect_name ]
Return an aspect given the name of the aspect
17,586
def classify_nodes ( graph , hub ) : node_stats = defaultdict ( lambda : defaultdict ( list ) ) for u , v , data in graph . edges ( data = True ) : if hub == u : h , o = u , v if data [ 'i' ] != 'Complex' : node_stats [ o ] [ 'up' ] . append ( - 1 ) else : node_stats [ o ] [ 'up' ] . append ( 0 ) elif hub == v : h , o ...
Classify each node based on its type and relationship to the hub .
17,587
def get_attributes ( aspect , id ) : attributes = { } for entry in aspect : if entry [ 'po' ] == id : attributes [ entry [ 'n' ] ] = entry [ 'v' ] return attributes
Return the attributes pointing to a given ID in a given aspect .
17,588
def cx_to_networkx ( cx ) : graph = networkx . MultiDiGraph ( ) for node_entry in get_aspect ( cx , 'nodes' ) : id = node_entry [ '@id' ] attrs = get_attributes ( get_aspect ( cx , 'nodeAttributes' ) , id ) attrs [ 'n' ] = node_entry [ 'n' ] graph . add_node ( id , ** attrs ) for edge_entry in get_aspect ( cx , 'edges'...
Return a MultiDiGraph representation of a CX network .
17,589
def get_quadrant_from_class ( node_class ) : up , edge_type , _ = node_class if up == 0 : return 0 if random . random ( ) < 0.5 else 7 mappings = { ( - 1 , 'modification' ) : 1 , ( - 1 , 'amount' ) : 2 , ( - 1 , 'activity' ) : 3 , ( 1 , 'activity' ) : 4 , ( 1 , 'amount' ) : 5 , ( 1 , 'modification' ) : 6 } return mappi...
Return the ID of the segment of the plane corresponding to a class .
17,590
def get_coordinates ( node_class ) : quadrant_size = ( 2 * math . pi / 8.0 ) quadrant = get_quadrant_from_class ( node_class ) begin_angle = quadrant_size * quadrant r = 200 + 800 * random . random ( ) alpha = begin_angle + random . random ( ) * quadrant_size x = r * math . cos ( alpha ) y = r * math . sin ( alpha ) re...
Generate coordinates for a node in a given class .
17,591
def get_layout_aspect ( hub , node_classes ) : aspect = [ { 'node' : hub , 'x' : 0.0 , 'y' : 0.0 } ] for node , node_class in node_classes . items ( ) : if node == hub : continue x , y = get_coordinates ( node_class ) aspect . append ( { 'node' : node , 'x' : x , 'y' : y } ) return aspect
Get the full layout aspect with coordinates for each node .
17,592
def get_node_by_name ( graph , name ) : for id , attrs in graph . nodes ( data = True ) : if attrs [ 'n' ] == name : return id
Return a node ID given its name .
17,593
def add_semantic_hub_layout ( cx , hub ) : graph = cx_to_networkx ( cx ) hub_node = get_node_by_name ( graph , hub ) node_classes = classify_nodes ( graph , hub_node ) layout_aspect = get_layout_aspect ( hub_node , node_classes ) cx [ 'cartesianLayout' ] = layout_aspect
Attach a layout aspect to a CX network given a hub node .
17,594
def get_metadata ( doi ) : url = crossref_url + 'works/' + doi res = requests . get ( url ) if res . status_code != 200 : logger . info ( 'Could not get CrossRef metadata for DOI %s, code %d' % ( doi , res . status_code ) ) return None raw_message = res . json ( ) metadata = raw_message . get ( 'message' ) return metad...
Returns the metadata of an article given its DOI from CrossRef as a JSON dict
17,595
def doi_query ( pmid , search_limit = 10 ) : pubmed_meta_dict = pubmed_client . get_metadata_for_ids ( [ pmid ] , get_issns_from_nlm = True ) if pubmed_meta_dict is None or pubmed_meta_dict . get ( pmid ) is None : logger . warning ( 'No metadata found in Pubmed for PMID%s' % pmid ) return None pubmed_meta = pubmed_met...
Get the DOI for a PMID by matching CrossRef and Pubmed metadata .
17,596
def get_agent_rule_str ( agent ) : rule_str_list = [ _n ( agent . name ) ] if isinstance ( agent , ist . Agent ) : for mod in agent . mods : mstr = abbrevs [ mod . mod_type ] if mod . residue is not None : mstr += mod . residue if mod . position is not None : mstr += mod . position rule_str_list . append ( '%s' % mstr ...
Construct a string from an Agent as part of a PySB rule name .
17,597
def add_rule_to_model ( model , rule , annotations = None ) : try : model . add_component ( rule ) if annotations : model . annotations += annotations except ComponentDuplicateNameError : msg = "Rule %s already in model! Skipping." % rule . name logger . debug ( msg )
Add a Rule to a PySB model and handle duplicate component errors .
17,598
def get_create_parameter ( model , param ) : norm_name = _n ( param . name ) parameter = model . parameters . get ( norm_name ) if not param . unique and parameter is not None : return parameter if param . unique : pnum = 1 while True : pname = norm_name + '_%d' % pnum if model . parameters . get ( pname ) is None : br...
Return parameter with given name creating it if needed .
17,599
def get_uncond_agent ( agent ) : agent_uncond = ist . Agent ( _n ( agent . name ) , mutations = agent . mutations ) return agent_uncond
Construct the unconditional state of an Agent .