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Syntex filed for a patent for the synthesis of the double-bond isomer 13 of norethindrone called noretynodrel. Noretynodrel is converted into norethisterone under acidic conditions, such as those in the human stomach, and the new patent did not infringe on the patent. Searle obtained approval to market noretynodrel before received its approval. By 1964 three companies, including Syntex, G.D. Searle, and Johnson & Johnson under the Ortho Pharmaceutical brand, were marketing 2-mg doses of the norethindrone. Syntex's submission of a fraudulent toxicology analysis of naproxen largely led to the Food and Drug Administration's uncovering of extensive scientific misconduct by Industrial Bio-Test Laboratories in 1976.
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Location hypotheses of Atlantis It is located about 25 kilometers from the continental shelf and about 60 km off the coast of Asturias, and Lastres between Ribadesella. Its top is now 425 meters below the sea. It is 50 kilometers from east to west and 18 km from north to south. Ribero-Meneses hypothesized that is part of the continental margin that broke off at least 12000 years ago as the result of tectonic processes that occurred at the end of the last ice age. He argues that they created a tsunami with waves with heights of hundreds of meters and that the few survivors had to start virtually from scratch. Detailed studies of the geology of the Le Danois Bank region have refuted the hypothesis proposed by Jorge Maria Ribero-Meneses that the Le Danois Bank was created by the collapse of the northern Cantabrian continental margin about 12,000 years ago. The Le Danois Bank represents part of the continental margin that have been uplifted by thrust faulting when the continental margin overrode oceanic crust during the Paleogene and Neogene periods. Along the northern edge of the Le Danois Bank, Precambrian granulite and Mesozoic sedimentary rocks have been thrust northward over Miocene and Oligocene marine sediments. The basin separating the Le Danois Bank from the Cantabrian continental margin to the south is a graben that simultaneously formed as a result of normal faulting associated with the thrust faulting
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Goodwin Liu On May 19, 2011, the Senate rejected cloture in a mostly party-line vote of 52–43, with all but one Democrat (Ben Nelson) voting in favor of cloture and all but one Republican (Lisa Murkowski) voting against. He became the first Obama judicial nominee to be successfully filibustered in the Senate. With the makeup of the Senate unlikely to change until after the 2012 election, Liu withdrew his name from consideration on May 25, 2011. On July 29, 2011, three days after California Governor Jerry Brown nominated Liu to a seat on the Supreme Court of California, President Obama formally notified the Senate that he was withdrawing Liu's nomination for the 9th Circuit. In a talk before The City Club of Cleveland on February 22, 2013, Liu commented that the confirmation process is "inherently a political process" and "the Constitution was designed to make it a political process." He noted, however, that the problem with the confirmation process is that it has become transformed into requiring 60 votes as opposed to a bare majority, which was not part of the Constitutional design. On July 26, 2011, California Gov. Jerry Brown nominated Liu to a seat on the Supreme Court of California. In submitting his nomination, Brown said that "[Liu] is a nationally recognized expert on constitutional law and has experience in private practice, [in] government service and in the academic community. I know that he will be an outstanding addition to our state supreme court
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Volute (pump) A volute is a curved funnel that increases in area as it approaches the discharge port. The volute of a centrifugal pump is the casing that receives the fluid being pumped by the impeller, maintaining the velocity of the fluid through to the diffuser. As liquid exits the impeller it has high kinetic energy and the volute directs this flow through to the discharge. As the fluid travels along the volute it is joined by more and more fluid exiting the impeller but, as the cross sectional area of the volute increases, the velocity is maintained if the pump is running close to the design point. If the pump has a low flow rate then the velocity will decrease across the volute leading to a pressure rise causing a cross thrust across the impeller that we see as vibration. If the pump flow is higher than design the velocity will increase across the volute and the pressure will decrease according to the first law of thermodynamics. This will cause a side thrust in the opposite direction to that caused by low flow but the result is the same - vibration with resultant short bearing and seal life. The volute does not convert kinetic energy into pressure - that is done at the diffuser by reducing liquid velocity while increasing pressure. The name "volute" is inspired by the resemblance of this kind of casing to the scroll-like part near the top of an ionic order column in classical architecture, called a volute
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DNA condensation can be induced "in vitro" either by applying external force to bring the double helices together, or by inducing attractive interactions between the DNA segments. The former can be achieved e.g. with the help of the osmotic pressure exerted by crowding neutral polymers in the presence of monovalent salts. In this case, the forces pushing the double helices together are coming from entropic random collisions with the crowding polymers surrounding DNA condensates, and salt is required to neutralize DNA charges and decrease DNA-DNA repulsion. The second possibility can be realized by inducing attractive interactions between the DNA segments by multivalent cationic charged ligands (multivalent metal ions, inorganic cations, polyamines, protamines, peptides, lipids, liposomes and proteins). Condensation of long double-helical DNAs is a sharp phase transition, which takes place within a narrow interval of condensing agent concentrations.[ref] Since the double helices come very closely to each other in the condensed phase, this leads to the restructuring of water molecules, which gives rise to the so-called hydration forces.[ref] To understand attraction between negatively charged DNA molecules, one also must account for correlations between counterions in the solution.[ref] by proteins can exhibit hysteresis, which can be explained using a modified Ising model
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Haptic communication It turns out that the rhesus monkeys spent most of their time with the terry cloth mother, over the wire surrogate with a bottle of food, which indicates that they preferred touch, warmth, and comfort over sustenance. Touch can come in many different forms, some can promote physical and psychological well-being. A warm, loving touch can lead to positive outcomes while a violent touch can ultimately lead to a negative outcome. The sense of touch allows one to experience different sensations such as: pleasure, pain, heat, or cold. One of the most significant aspects of touch is the ability to convey and enhance physical intimacy. The sense of touch is the fundamental component of haptic communication for interpersonal relationships. Touch can be categorized in many terms such as positive, playful, control, ritualistic, task-related or unintentional. It can be both sexual (kissing is one example that some perceived as sexual), and platonic (such as hugging or a handshake). Striking, pushing, pulling, pinching, kicking, strangling and hand-to-hand fighting are forms of touch in the context of physical abuse. Heslin outlines five haptic categories: The intent of a touch is not always exclusive and touching can evolve to each one of Heslin's categories. Managers should know the effectiveness of using touch while communicating to subordinates, but need to be cautious and understand how touch can be misunderstood
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Multi-screen video In the fields of broadcasting and content delivery, multiscreen video describes video content that is transformed into multiple formats, bit rates and resolutions for display on devices such as televisions, mobile phones, tablets and computers. Additional devices may include video game consoles such as the Xbox 360, or internet enabled television. As video moved to digital formats, content began to stream across IP networks. The term developed as more electronic devices transmitted video. Technical and advertising professionals began to refer to video content transmitted across multiple devices as multiscreen video. Notable industry usage includes The Nielsen Company, Cisco Systems and Google.
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Foreign policy The organization Foreign Policy Interrupted recognized the gender disparity in foreign policy expert representation and is amplifying the number of female voices in foreign policy media coverage. Government officials involved in making foreign policy often perceive risk in giving away information about their policy-making processes and do not discuss the subject since control of information is itself often a part of foreign policy. The vast record of empirical data and research is given academic attention to fit it into the framework of a general theory of foreign policy. The second group of writers has made contributions to its development in many ways:
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Criticism of The Walt Disney Company " Meanwhile, Kelly McBride of the nonprofit journalism organization the Poynter Institute in an interview with "The Washington Post" said “You’re turning the journalist into a salesperson and asking them to upsell the product. That’s not the relationship you want the journalist to have with the audience member. You want that relationship to be about trust in the journalist’s expertise.” Al Lutz, who has written about Disney since the 1990s, often writes about a perceived decline in value and quality at Disney's theme parks, chiefly Disneyland and the neighboring park that opened in 2001, Disney California Adventure Park. Much of his criticism was directed at Paul Pressler, the one-time president of Disneyland who later was named chairman of Walt Disney Parks and Resorts, and Cynthia Harriss, Pressler's successor as Disneyland's president. From 1996-2002, Lutz maintained a set of sarcastic Web pages called "Promote Paul Pressler!", whose stated goal was "getting current Disneyland Resort President Paul Pressler promoted to a new job "somewhere else" within The Walt Disney Company!" Lutz's July 2006 report on the alleged antics of Lindsay Lohan during a private party held at Disneyland for her 20th birthday drew a rebuke from a representative for the actress, who said that reports of bad behavior were "complete bull". This report brought Lutz's website, MiceAge, briefly into the spotlight, and established Lutz as a Disney watchdog in the mainstream media
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Religious views of Charles Darwin In particular the Unitarians and free religionists, proud of his Dissenting upbringing, supported his naturalistic views. The Unitarian William Carpenter carried a resolution praising Darwin's unravelling of "the immutable laws of the Divine Government", shedding light on "the progress of humanity", and the Unitarian preacher John White Chadwick from New York wrote that "The nation's grandest temple of religion opened its gates and lifted up its everlasting doors and bade the King of Science come in." Darwin decided to leave a posthumous memoir for his family, and on Sunday 28 May 1876 he began "Recollections of the Development of my mind and character". He found this candid private memoir easy going, covering his childhood, university, life on the "Beagle" expedition and developing work in science. A section headed "Religious Belief" opened just before his marriage, and frankly discussed his long disagreement with Emma. At first he had been unwilling to give up his faith, and had tried to "invent evidence" supporting the Gospels, but just as his clerical career had died a slow "natural death", so too did his belief in "Christianity as a divine revelation". "Inward convictions and feelings" had arisen from natural selection, as had survival instincts, and could not be relied on. He was quick to show Emma's side of the story and pay tribute to "your mother, ... so infinitely my superior in every moral quality ... my wise adviser and cheerful comforter"
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Dead Sea Scrolls 0% of the scrolls), and sheets of bronze composed of about 99.0% copper and 1.0% tin (approximately 1.5% of the scrolls). For those scrolls written on animal hides, scholars with the Israeli Antiquities Authority, by use of DNA testing for assembly purposes, believe that there may be a hierarchy in the religious importance of the texts based on which type of animal was used to create the hide. Scrolls written on goat and calf hides are considered by scholars to be more significant in nature, while those written on gazelle or ibex are considered to be less religiously significant in nature. In addition, tests by the National Institute of Nuclear Physics in Sicily, Italy, have suggested that the origin of parchment of select Dead Sea Scroll fragments is from the Qumran area itself, by using X-ray and Particle Induced X-ray emission testing of the water used to make the parchment that were compared with the water from the area around the Qumran site. The that were found were originally preserved by the dry, arid, and low humidity conditions present within the Qumran area adjoining the Dead Sea. In addition, the lack of the use of tanning materials on the parchment of the and the very low airflow in the Qumran caves also contributed significantly to their preservation. Some of the scrolls were found stored in clay jars within the Qumran caves, further helping to preserve them from deterioration
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The Best Man Holiday When Lance visits Harper and Robyn at their house in New York City, Harper gets a phone call from Q wherein Q announces his anticipated marriage but immediately warns Harper that he better not have had slept with his bride. In October 2011, it was announced that a sequel to the 1999 film "The Best Man" was in development. On February 22, 2013, it was announced that the film would be titled "The Best Man Holiday". In March 2013, Terrence Howard who plays Quentin Spivey in the film revealed details about the film, saying: "I think it's going to be amazing film and I get teary-eyed thinking about it because there's some tragedy in it. That's all I'll say…[Director and screenwriter] Malcolm Lee showed us what intelligent young black people were capable of in The Best Man I, but The Best Man II, it shows where people go, whether they're doing the right thing or the wrong thing, and how much we need each other within our community." Principal photography and production began in April 2013. "The Best Man Holiday" debuted with a $10.7 million Friday total, notably beating "" for the top box office spot of that day. "The Best Man Holiday" did even better the next day earning $12.4 million on Saturday. It then went on to be the number two film of the weekend, taking in close to $30.6 million. On Rotten Tomatoes, the film has an approval rating of 69% based on 85 reviews, with an average rating of 5.9/10
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Global Zero (campaign) Global Zero Commissioners Senator Chuck Hagel and Ambassador Richard Burt met with President Medvedev in Moscow and discussed the agenda. On April 1, 2009 the two presidents met in London and issued a historic joint statement committing their "two countries to achieving a nuclear free world" and three days later in a speech in Prague, President Obama declared his intention to "seek to include all nuclear weapons states in this endeavor." On the day of the meeting, "the Times" (of London) published an op-ed authored by six Global Zero leaders. Negotiations began between the two countries for a New START nuclear arms reduction treaty. Prior to the July 6–8, 2009 Obama-Medvedev Summit, the international Global Zero Commission of 23 political and military leaders released a comprehensive, end-to-end plan for the elimination of nuclear weapons over the next 20 years. At their Summit, Presidents Obama and Medvedev announced a framework agreement for new reductions to U.S. and Russian arsenals—a critical first step toward multilateral negotiations for the elimination of all nuclear weapons as called for in the Global Zero Action Plan (GZAP). At the 35th G8 summit in July 2009, world leaders announced their support of the Obama-Medvedev commitment to eliminate all nuclear weapons and called on all countries to "undertake further steps in nuclear disarmament
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Mercury(I) chloride Eder (hence the name Eder reaction) in 1880 and reinvestigated by W. E. Rosevaere in 1929. Mercury(I) bromide, HgBr, is light yellow, whereas mercury(I) iodide, HgI, is greenish in colour. Both are poorly soluble. Mercury(I) fluoride is unstable in the absence of a strong acid. Mercurous chloride is toxic, although due to its low solubility in water it is generally less dangerous than its mercuric chloride counterpart. It was used in medicine as a diuretic and purgative (laxative) in the United States from the late 1700s through the 1860s. Calomel was also a common ingredient in teething powders in Britain up until 1954, causing widespread mercury poisoning in the form of pink disease, which at the time had a mortality rate of 1 in 10. These medicinal uses were later discontinued when the compound's toxicity was discovered. It has also found uses in cosmetics as soaps and skin lightening creams, but these preparations are now illegal to manufacture or import in many countries including the US, Canada, Japan and the European Union. A study of workers involved in the production of these preparations showed that the sodium salt of 2,3-dimercapto-1-propanesulfonic acid (DMPS) was effective in lowering the body burden of mercury and in decreasing the urinary mercury concentration to normal levels.
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Electron hole Since force = mass × acceleration, a negative-effective-mass electron near the top of the valence band would move the opposite direction as a positive-effective-mass electron near the bottom of the conduction band, in response to a given electric or magnetic force. Therefore, a hole moves this way as well. From the above, a hole (1) carries a positive charge, and (2) responds to electric and magnetic fields as if it had a positive charge and positive mass. (The latter is because a particle with positive charge and positive mass respond to electric and magnetic fields in the same way as a particle with a negative charge and negative mass.) That explains why holes can be treated in all situations as ordinary positively charged quasiparticles. In some semiconductors, such as silicon, the hole's effective mass is dependent on a direction (anisotropic), however a value averaged over all directions can be used for some macroscopic calculations. In most semiconductors, the effective mass of a hole is much larger than that of an electron. This results in lower mobility for holes under the influence of an electric field and this may slow down the speed of the electronic device made of that semiconductor. This is one major reason for adopting electrons as the primary charge carriers, whenever possible in semiconductor devices, rather than holes. Also, why NMOS logic is faster than PMOS logic. However, in many semiconductor devices, both electrons "and" holes play an essential role
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Archaeoastronomy The lack of artifacts caused concern for some archaeologists and the petrofabric analysis was inconclusive, but further research at Maes Howe and on the Bush Barrow Lozenge led MacKie to conclude that while the term 'science' may be anachronistic, Thom was broadly correct upon the subject of high-accuracy alignments. In contrast Clive Ruggles has argued that there are problems with the selection of data in Thom's surveys. Others have noted that the accuracy of horizon astronomy is limited by variations in refraction near the horizon. A deeper criticism of Green archaeoastronomy is that while it can answer "whether" there was likely to be an interest in astronomy in past times, its lack of a social element means that it struggles to answer "why" people would be interested, which makes it of limited use to people asking questions about the society of the past. Keith Kintigh wrote: "To put it bluntly, in many cases it doesn't matter much to the progress of anthropology whether a particular archaeoastronomical claim is right or wrong because the information doesn’t inform the current interpretive questions." Nonetheless the study of alignments remains a staple of archaeoastronomical research, especially in Europe
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Depolymerization (or depolymerisation) is the process of converting a polymer into a monomer or a mixture of monomers. This process is driven by an increase in entropy. The tendency of polymers to depolymerize is indicated by their ceiling temperature. At this temperature, the enthalpy of polymerization matches the entropy gained by converting a large molecule into monomers. Above the ceiling temperature, the rate of depolymerization is greater than the rate of polymerization, which inhibits the formation of the given polymer. is a very common process. Digestion of food involves depolymerization of macromolecules, such as proteins. It is relevant to polymer recycling. Sometimes the depolymerization is well behaved, and clean monomers can be reclaimed and reused for making new plastic. In other cases, such as polyethylene, depolymerization gives a mixture of products. These products are, for polyethylene, ethylene, propylene, isobutylene, 1-hexene and heptane. Out of these, only ethylene can be used for polyethylene production, so other gases must be turned into ethylene, sold, or otherwise be destroyed or be disposed of by turning them into other products. is also related to production of chemicals and fuels from biomass. In this case, reagents are typically required. A simple case is the hydrolysis of celluloses to glucose by the action of water. Generally this process requires an acid catalyst:
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Distributed-element model The most common approach is to roll up all the distributed capacitance into one lumped element in parallel with the inductance and resistance of the coil. This lumped model works successfully at low frequencies but falls apart at high frequencies where the usual practice is to simply measure (or specify) an overall "Q" for the inductor without associating a specific equivalent circuit.
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Cumene process This latter cumene converts into cumene radical and feeds back into subsequent chain formations of cumene hydroperoxides. A pressure of 5 atm is used to ensure that the unstable peroxide is kept in liquid state. Cumene hydroperoxide is then hydrolysed in an acidic medium (the Hock rearrangement) to give phenol and acetone. In the first step, the terminal hydroperoxy oxygen atom is protonated. This is followed by a step in which the phenyl group migrates from the benzyl carbon to the adjacent oxygen and a water molecule is lost, producing a resonance stabilized tertiary carbocation. The concerted mechanism of this step is similar to the mechanisms of the Baeyer–Villiger oxidation and also the oxidation step of hydroboration-oxidation. In 2009, an acidified bentonite clay was proven to be a more economical catalyst than sulfuric acid as the acid medium. As shown below, the resulting carbocation is then attacked by water, a proton is then transferred from the hydroxy oxygen to the ether oxygen, and finally the ion falls apart into phenol and acetone. Crude acetone is hydrogenated in the liquid phase over Raney nickel or a mixture of copper and chromium oxide to give isopropyl alcohol. This process is useful, when it is coupled with excess acetone production. Modified cumene processes include different approaches. Mitsui & Co. developed additional step(s) to hydrogenating the acetone product and dehydrating the isopropanol product to propene, which is recycled as a starting reactant
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Shr-Hwa International Tower The () is a skyscraper located in West District, Taichung, Taiwan. It is the sixth tallest building in Taiwan and the tallest in central Taiwan. This building has a peculiar shape of a bamboo. The building is accessible North West from Taichung TRA station of the Taiwan Railway Administration.
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Host (biology) For example, sludge worms are sometimes considered "intermediate hosts" for salmonid whirling disease, even though the myxosporean parasite reproduces sexually inside them. In trichinosis, a disease caused by roundworms, the host has reproductive adults in its digestive tract and immature juveniles in its muscles, and is therefore both an intermediate and a definitive host. Micropredation is an evolutionarily stable strategy within parasitism, in which a small predator lives parasitically on a much larger host plant, eating parts of it. The range of plants on which a herbivorous insect feeds is known as its host range. This can be wide or narrow, but it never includes all plants. A small number of insects are monophagous, feeding on a single plant. The silkworm larva is one of these, with mulberry leaves being the only food consumed. More often, an insect with a limited host range is oligophagous, being restricted to a few closely related species, usually in the same plant family. The diamondback moth is an example of this, feeding exclusively on brassicas, and the larva of the potato tuber moth feeds on potatoes, tomatoes and tobacco, all members of the same plant family, Solanaceae. Herbivorous insects with a wide range of hosts in various different plant families are known as polyphagous. One example is the buff ermine moth whose larvae feed on alder, mint, plantain, oak, rhubarb, currant, blackberry, dock, ragwort, nettle and honeysuckle
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Self-driving car Numbers from the National Safety Council on killed and injured people on US roads multiplied by the average costs of a single incident reveal that an estimated US$500 billion loss may be imminent for the US healthcare industry when autonomous vehicles are dominating the roads. It is likely the anticipated decrease in traffic accidents will positively contribute to the widespread acceptance of autonomous vehicles, as well as the possibility to better allocate healthcare resources. As collisions are less likely to occur, and the risk for human errors is reduced significantly, the repair industry will face an enormous reduction of work that has to be done on the reparation of car frames. Meanwhile, as the generated data of the autonomous vehicle is likely to predict when certain replaceable parts are in need of maintenance, car owners and the repair industry will be able to proactively replace a part that will fail soon. This "Asset Efficiency Service" would implicate a productivity gain for the automotive repair industry. As fewer collisions implicate less money spent on repair costs, the role of the insurance industry is likely to be altered as well. It can be expected that the increased safety of transport due to autonomous vehicles will lead to a decrease in payouts for the insurers, which is positive for the industry, but fewer payouts may imply a demand drop for insurances in general. The insurance industry may have to create new insurance models in the near future to accommodate the changes
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Deferred tax Temporary differences are usually calculated on the differences between the carrying amount of an asset or liability recognized in the statements of financial position and the amount attributed to that asset or liability for tax at the beginning and end of the year. The differences in the charges to the profit and loss account compared to the amounts taxable or allowable can also be calculated and should reconcile the change in position at the beginning and end of the year. The basic principle of accounting for deferred tax under a temporary difference approach can be illustrated using a common example in which a company has fixed assets that qualify for tax depreciation. The following example assumes that a company purchases an asset for $1,000 which is depreciated for accounting purposes on a straight-line basis of five years of $200/year. The company claims tax depreciation of 25% per year on a reducing balance basis. The applicable rate of corporate income tax is assumed to be 35%, and the net value is subtracted. As the tax value, or tax base, is lower than the accounting value, or book value, in years 1 and 2, the company should recognize a deferred tax liability. This also reflects that the company has claimed tax depreciation in excess of the expense for accounting depreciation recorded in its accounts, whereas in the future the company should claim less tax depreciation in total than accounting depreciation in its accounts
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Origin of the Albanians This theory was developed by the Austrian linguist Johann Georg von Hahn in his work "Albanesische Studien" in 1854. According to Hahn, the Pelasgians were the original proto-Albanians and the language spoken by the Pelasgians, Illyrians, Epirotes and ancient Macedonians were closely related. This theory quickly attracted support in Albanian circles, as it established a claim of predecence over other Balkan nations, particularly the Greeks. In addition to establishing "historic right" to territory this theory also established that the ancient Greek civilization and its achievements had an "Albanian" origin. The theory gained staunch support among early 20th-century Albanian publicists. This theory is rejected by scholars today. In contemporary times with the Arvanite revival of the Pelasgian theory, it has also been recently borrowed by other Albanian speaking populations within and from Albania in Greece to counter the negative image of their communities.
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Franco Andrea Bonelli In the same year, he discovered Bonelli's eagle ("Hieraaetus fasciatus") that was likewise named by Vieillot in 1822. The successor of Bonelli at the Turin Museum was Carlo Giuseppe Gené. Bonelli is most notable for his work on birds and on the beetle family Carabidae. Since he was an early worker on Coleoptera many of his genera later became Families, sub families and tribes. Also many of his genera survive. Instances are the: The last two are founding works of entomology, introducing many new taxa.
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Reformed epistemology Plantinga seeks to defend this view of proper function against alternative views of proper function proposed by other philosophers which he groups together as "naturalistic", including the "functional generalization" view of John Pollock, the evolutionary/etiological account provided by Ruth Millikan, and a dispositional view held by John Bigelow and Robert Pargetter. Plantinga also discusses his evolutionary argument against naturalism in the later chapters of "Warrant and Proper Function". In 2000 Plantinga's third volume, "Warranted Christian Belief", was published. In this volume, Plantinga's warrant theory is the basis for his theological end: providing a philosophical basis for Christian belief, an argument for why Christian theistic belief can enjoy warrant. In the book, he develops two models for such beliefs, the "A/C" (Aquinas/Calvin) model, and the "Extended A/C" model. The former attempts to show that a belief in God can be justified, warranted and rational, while the Extended model tries to show that core Christian theological beliefs, including the Trinity, the Incarnation, the resurrection of Christ, the atonement, salvation, etc. can be warranted. Under this model, Christians are warranted in their beliefs because of the work of the Holy Spirit in bringing those beliefs about in the believer
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EXAPT ("EXtended Subset of APT") is a production oriented programming language to generate NC programs with control information for machining tools and enables to consider production-related issues of various machining processes. has developed historically regarding industrial requirements. Through the years software solutions for the manufacturing industry were created which today form a broad scalable portfolio with future-oriented products and services. Today the tradename is primarily understood as CAD/CAM-System and production data und tool management Software of the German company Systemtechnik GmbH based in Aachen. is a modularly built programming system for all NC machining operations as Due to the modular structure the main product groups EXAPTcam and EXAPTpdo are gradually expandable and permit individual software solutions for the manufacturing industry used individually and also in compound with an existing IT environment. EXAPTcam meets the requirements for NC planning especially for the cutting operations as turning, drilling and milling up to 5-axis simultaneous machining. Thereby new process technologies, tool and machine concepts are constantly involved. In the NC programming data from different sources as 3D CAD models, drawings or tables can flow in. The possibilities of NC programming reaches from the language-oriented to the feature-oriented NC programming. The integrated knowledge database and intelligent and scalable automatisms support the user
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Johnson's Building, The Rocks Johnson's Building is a heritage-listed former retail stores and now stock exchange offices, bar and restaurant located at 233-235 George Street in the inner city Sydney suburb of The Rocks in the City of Sydney local government area of New South Wales, Australia. It was designed by Walter Liberty Vernon and built in 1912. It is also known as Chamber of Commerce Building and Johnson's Overalls Building (Johnsons). The property is owned by Property NSW, an agency of the Government of New South Wales. It was added to the New South Wales State Heritage Register on 10 May 2002. The site occupied by 233-35 George Street was once part of the original Parade Ground of the Colony. By the 1820s this corner site was still owned by the NSW Government. In the site was subdivided into four allotments. Of these, three fronted George Street and one Grosvenor Street. A small lane which opened onto Grosvenor Street separated this latter from those with George Street frontages. The corner site at Grosvenor and George Streets was purchased from the Government in 1831 by Anthony Hordern and remained the property of the Hordern family until the NSW Government Rocks Resumption Act of 1901. The building erected by Hordern on this site, which appears in Fowles engraving of 1848, remained essentially unaltered until 1911/12 when demolition occurred for the widening of George Street, together with the 1845 building to the north owned by Alexander Douglas from 1831 until 1901
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Tuscarora language Onomatopoeia, from Tuscarora or other languages, is less common than other words from other languages or verbal descriptions that turned to nominals. In many cases a pronominal prefix has dropped off, so that only the minimal stem remains. Ownership is divided into alienable and inalienable possession, each of which type has its own construction. An example of inalienable possession would be someone's body part—this cannot be disputed. An example of alienable possession would be a piece of paper held by someone. Attributive suffixes come in many forms: A diminutive indicates something smaller; an augmentive makes something bigger. A simple example would be a diminutive suffix added to the word "cat" to form a word meaning "small cat." A more abstract example would be the diminutive of "trumpet" forming "pipe." Both diminutives and augmentives have suffixes that indicate both smallness and plurality. A (certain) diminutive can be added to any functional nominal. Augmentives usually combine with other morphemes, forming more specific stems. Attributive suffixes can be added to any word that functions as a nominal, even if it is a verb or particle. The basic word order in Tuscarora is SVO (subject–verb–object), but this can vary somewhat and still form grammatical sentences, depending on who the agents and patients are. For example: If two nouns of the same relative "status" are together in a sentence, the SVO word order is followed
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Elizabethan era On balance, it can be said that Elizabeth provided the country with a long period of general if not total peace and generally increased prosperity due in large part to stealing from Spanish treasure ships, raiding settlements with low defenses, and selling African slaves. Having inherited a virtually bankrupt state from previous reigns, her frugal policies restored fiscal responsibility. Her fiscal restraint cleared the regime of debt by 1574, and ten years later the Crown enjoyed a surplus of £300,000. Economically, Sir Thomas Gresham's founding of the Royal Exchange (1565), the first stock exchange in England and one of the earliest in Europe, proved to be a development of the first importance, for the economic development of England and soon for the world as a whole. With taxes lower than other European countries of the period, the economy expanded; though the wealth was distributed with wild unevenness, there was clearly more wealth to go around at the end of Elizabeth's reign than at the beginning. This general peace and prosperity allowed the attractive developments that "Golden Age" advocates have stressed. The Elizabethan Age was also an age of plots and conspiracies, frequently political in nature, and often involving the highest levels of Elizabethan society. High officials in Madrid, Paris and Rome sought to kill Elizabeth, a Protestant, and replace her with Mary, Queen of Scots, a Catholic. That would be a prelude to the religious recovery of England for Catholicism
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Philosophy of business The philosophy of business considers the fundamental principles that underlie the formation and operation of a business enterprise; the nature and purpose of a business, and the moral obligations that pertain to it. Philipp Blom summarises the development and impact of business-centric ideas in society prior to the global financial crisis of 2008: [...] Friedrich von Hayek and Ludwig von Mises [...] were Europeans who had passed their formative years in the chaotic interwar years and whose conclusion was that state intervention and planned economies were hallmarks of dictatorship [...]. They believed that it was healthier to take ideology out of politics and base the workings of society on the objective, nonideological laws of the free market. [...] The Enlightenment cult of reason and of the common good was replaced by the concepts of rationalization and the maximization of profits, which were applied to a reevaluation of social institutions - infrastructure, schools, universities, prisons, health care, and so on - according to business-driven criteria of profitability and cost-effectiveness. Especially in the United States but also increasingly in Europe, we began to run our societies as businesses. Beginning in the late 1970s and gaining speed in the 1980s, this gospel changed and polarized our societies - but it also provided an umbrella of meaning and necessity under which we could hide from challenges from without as well as doubts from within
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Theodor W. Adorno Adorno's own recently published "Minima Moralia" was not only well received in the press, but also met with great admiration from Thomas Mann, who wrote to Adorno from America in 1952: Yet Adorno was no less moved by other public events: protesting the publication of Heinrich Mann's novel "Professor Unrat" with its film title, "The Blue Angel"; declaring his sympathy with those who protested the scandal of big-game hunting and penning a defense of prostitutes. Because Adorno's American citizenship would have been forfeited by the middle of 1952 had he continued to stay outside the country, he returned once again to Santa Monica to survey his prospects at the Hacker Foundation. While there he wrote a content analysis of newspaper horoscopes (now collected in "The Stars Down to Earth"), and the essays "Television as Ideology" and "Prologue to Television"; even so, he was pleased when, at the end of ten months, he was enjoined to return as co-director of the Institute. Back in Frankfurt, he renewed his academic duties and, from 1952 to 1954, completed three essays: "Notes on Kafka", "Valéry Proust Museum", and an essay on Schoenberg following the composer's death, all of which were included in the 1955 essay collection "Prisms". In response to the publication of Thomas Mann's "The Black Swan", Adorno penned a long letter to the author, who then approved its publication in the literary journal "Akzente". A second collection of essays, "Notes to Literature", appeared in 1958
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Sutton Hoo helmet " The helmets from Ultuna, Vendel 14 and Valsgärde 5 all used iron strips as neck protection; five strips hung from the rear of the Vendel 14 and Valsgärde 5 brow bands, and though only two strips survive from the Ultuna helmet, others would have hung alongside them. Camail was used on the remaining helmets, from Valsgärde 6, 7 and 8, and from Vendel 1 and 12. Fragmentary remains from Vendel 10 and 11, and from Solberga, likewise suggest camail. In terms of cheek protection, only two helmets had something other than continuations of the camail or iron strips used to protect the neck. The Vendel 14 helmet had cheek guards, but of "a differing version well forward on the face" of those on the Sutton Hoo helmet. Though not fully reconstructable, fragments from the Broe helmet suggest a configuration similar to those on the Vendel 14 helmet. Finally, the widely varying caps on each Scandinavian helmet all share one feature: None is similar to the cap on the Sutton Hoo helmet. The basic form of the helmets from Vendel, Valsgärde, Ultuna and Broe all started with a brow band and nose-to-nape band. The Ultuna helmet had its sides filled in with latticed iron strips, while each side on the Valsgärde 8 helmet was filled in with six parallel strips running from the brow band to the nose-to-nape brand. The remaining four helmets—excepting those from Vendel 1 and 10, and Broe, which are too fragmentary to determine their exact construction—all employed two lateral bands and sectional infills
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Yttrium phosphide is an inorganic compound of yttrium and phosphorus with the chemical formula YP. The compound may be also classified as yttrium(III) phosphide. Heating (500–1000 °C) of pure substances in a vacuum: Y + P → YP forms cubic crystals. Ytttium phosphide is a semiconductor used in laser diodes, and in high power and frequency applications.
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Hoosac Tunnel Haupt had excavated , or about a fifth of the distance, at that point. He left and became a Union Army railroad engineer and general in the American Civil War. In 1862, the Troy and Greenfield Railroad defaulted on its loan from the Commonwealth of Massachusetts, which foreclosed on the mortgage and took control of the railroad, including the tunnel project. The state sent engineer Charles Storrow to Europe to study modern tunneling techniques, including the use of nitroglycerin and compressed air. In 1863 the state, with Alvah Crocker now superintendent of railroads, restarted the project and made Thomas Doane the chief engineer. In 1868, the Massachusetts state legislature appropriated $5 million to complete the project. Canadian engineer Walter Shanly (sometimes spelled Shanley) and his brother Francis took over the project from the state and remained through the completion of the tunnel boring. Among the consulting engineers at the time was Benjamin Henry Latrobe II, a noted civil engineer who was serving as the chief engineer of the Baltimore and Ohio Railroad. The final chief engineer was Bernard N. Farren, who took over on November 19, 1874, and on Thanksgiving Day that year, the last 16 feet of rock was removed beneath the town of North Adams. Farren completed the work, including enlarging sections of the tunnel, reinforcing weak areas with arching, completing drainage systems and completing the east tunnel facade. The first train passed through the tunnel on February 9, 1875
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International Council of Design In 1999 the position was officially changed to “Director” Thierry van Kerm held this during the period the Secretariat was based in Brussels from 1999–2005. In Montréal, Brenda Sanderson took over this role until 2012, followed by Marilena Farruggia until 2013 and Jovana Milović until 2015. From 2015 onwards, management of the Secretariat has been in the hands of Ana Masut. ico-D's Executive Board consists of individuals who are duly nominated and elected by ico-D's Member organisations at the biennial ico-D General Assembly. Members of the Executive Board serve in a volunteer position and donate their time and expertise to further Icograda's mandate. Board meetings are typically held four times a year in different locations around the world, usually in conjunction with regional meetings, seminars or other scheduled design events. Since 1963 and 2016, 26 ico-D boards have donated their leadership skills and time to furthering ico-D's goals and objectives. View a complete list of Executive Board members here. Peter Kneebone proposed the idea to establish an international organisation for graphic design and was involved in Icograda's founding
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Irish language The English administrator and traveller Fynes Moryson, writing in the last years of the 16th century, said that "the English Irish and the very citizens (excepting those of Dublin where the lord deputy resides) though they could speak English as well as we, yet commonly speak Irish among themselves, and were hardly induced by our familiar conversation to speak English with us". In Galway, a city dominated by Old English merchants and loyal to the Crown up to the Irish Confederate Wars (1641-1653), the use of the had already provoked the passing of an Act of Henry VIII (1536), ordaining as follows: The demise of native cultural institutions in the seventeenth century saw the social prestige of Irish diminish, and the gradual Anglicisation of the middle classes followed. The census of 1851 showed, however, that the towns and cities of Munster still had significant Irish-speaking populations. Much earlier, in 1819, James McQuige, a veteran Methodist lay preacher in Irish, wrote: "In some of the largest southern towns, Cork, Kinsale and even the Protestant town of Bandon, provisions are sold in the markets, and cried in the streets, in Irish". Irish speakers constituted over 40% of the population of Cork even in 1851. The 19th century saw a reduction in the number of Dublin's Irish speakers, in keeping with the trend elsewhere
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Muraqqa Akbar had an album, now dispersed, consisting entirely of portraits of figures at his enormous court which had a practical purpose; according to chroniclers he used to consult it when discussing appointments and the like with his advisors, apparently to jog his memory of who the people being discussed were. Many of them, like medieval European images of saints, carried objects associated with them to help identification, but otherwise the figures stand on a plain background. There are a number of fine portraits of Akbar, but it was under his successors Jahangir and Shah Jahan that the portrait of the ruler became firmly established as a leading subject in Indian miniature painting, which was to spread to both Muslim and Hindu princely courts across India. In the 18th and 19th centuries Indian artists working in the hybrid Indo-European Company style produced albums of miniatures for Europeans living in India as part of the British Raj and its French and Portuguese equivalents. Some Europeans collected or were given earlier Indian miniatures; the Large and Small Clive albums were presented to Lord Clive, and are now in the Victoria & Albert Museum in London. Others created albums of new work, tending to concentrate on animal portraits and the houses, horses and other possessions of this wealthy group. In the 19th century images of Indians and their costumes, often categorized by regional and ethnic type, or occupation, became very popular
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Cast iron Cast-iron beam bridges were used widely by the early railways, such as the Water Street Bridge in 1830 at the Manchester terminus of the Liverpool and Manchester Railway, but problems with its use became all too apparent when a new bridge carrying the Chester and Holyhead Railway across the River Dee in Chester collapsed killing five people in May 1847, less than a year after it was opened. The Dee bridge disaster was caused by excessive loading at the centre of the beam by a passing train, and many similar bridges had to be demolished and rebuilt, often in wrought iron. The bridge had been badly designed, being trussed with wrought iron straps, which were wrongly thought to reinforce the structure. The centres of the beams were put into bending, with the lower edge in tension, where cast iron, like masonry, is very weak. Nevertheless, cast iron continued to be used in inappropriate structural ways, until the Tay Rail Bridge disaster of 1879 cast serious doubt on the use of the material. Crucial lugs for holding tie bars and struts in the Tay Bridge had been cast integral with the columns, and they failed in the early stages of the accident. In addition, the bolt holes were also cast and not drilled. Thus, because of casting's draft angle, the tension from the tie bars was placed on the hole's edge rather than being spread over the length of the hole. The replacement bridge was built in wrought iron and steel. Further bridge collapses occurred, however, culminating in the Norwood Junction rail accident of 1891
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Jurin's law Jurin's law, or capillary rise, is the simplest analysis of capillary action—the induced motion of liquids in small channels—and states that the maximum height of a liquid in a capillary tube is inversely proportional to the tube's diameter. Capillary action is one of the most common fluid mechanical effects explored in the field of microfluidics. is named after James Jurin, who discovered it between 1718 and 1719. His quantitative law suggests that the maximum height of liquid in a capillary tube is inversely proportional to the tube's diameter. The difference in height between the surroundings of the tube and the inside, as well as the shape of the meniscus, are caused by capillary action. The mathematical expression of this law can be derived directly from hydrostatic principles and the Young–Laplace equation. allows the measurement of the surface tension of a liquid and can be used to derive the capillary length. The law is expressed as where It is only valid if the tube is cylindrical and has a radius ("r") smaller than the capillary length (formula_2). In terms of the capillary length, the law can be written as For a water-filled glass tube in air at standard conditions for temperature and pressure, at 20 °C, , and . For these values, the height of the water column is Thus for a radius glass tube in lab conditions given above, the water would rise an unnoticeable . However, for a radius tube, the water would rise , and for a radius tube, the water would rise
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Teletype Corporation The other two buildings were demolished. The had its roots in the Morkrum Company. In 1902, electrical engineer Frank Pearne approached Joy Morton, head of Morton Salt, seeking a sponsor for Pearne's research into the practicalities of developing a printing telegraph system. Joy Morton needed to determine whether this was worthwhile and so consulted mechanical engineer Charles Krum, who was vice president of the Western Cold Storage Company, which was run by Morton’s brother Mark Morton. Krum was interested in helping Pearne, so space was set up in a laboratory in the attic of Western Cold Storage. Frank Pearne lost interest in the project after a year, and left to become a teacher at Armour Institute, now Illinois Institute of Technology. Krum was prepared to continue Pearne’s work, and in August 1903 a patent was filed for a "typebar page printer". The present-day Pearne family disputes the claim that their ancestor lost interest, saying that Morton didn't pay him enough to support his family and that is why he left. It is perhaps noteworthy that many of the engineering staff of Teletype were educated at Armour/IIT, beginning with Howard Krum. In 1904, Krum filed a patent for a "type wheel printing telegraph machine" which was issued in August 1907. In 1906, the Morkrum Company was formed, with the company name combining the Morton and Krum names and reflecting the financial assistance provided by Joy Morton. This is the time when Charles Krum's son, Howard Krum, joined his father in this work
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Kitana Besides Mileena and Jade in "Mortal Kombat II" and Khameleon in "Mortal Kombat Trilogy", another character, Tanya, who was introduced in "Mortal Kombat 4", also began as a recolored version of with altered moves. Another character derived from is the crimson code-colored female ninja Skarlet, who was first rumored to be an Ermac-style glitch character and debuted as a playable in "MK2011". The moveset of Sonya Blade in "Mortal Kombat 3" is very similar to Kitana's in "MKII". Kitana's official measurements in "Deadly Alliance" are 128 lb. weight and 5'9" height. Her weapon of choice is a pair of razor-edged steel fans, inspired by Japanese war fans and originally being fully metal. Kitana's fans during the production of "MKII" were not actually steel but made of a reflective paper material, and were Zamiar's own training fans. Following her "MKII" debut, was repeatedly removed from further sequels due to various circumstances, only to always return in a port or an update, as it was the case with "UMK3"/"Trilogy" after her absence in "MK3", "Gold" after her absence in "MK4", and "" after her absence in "Deception". In "Gold", uses a throwing weapon, the "Flying Blade", which is similar to Tanya's sharp boomerang due to the two characters' linked development history in the original version of "MK4". In "MKX", can use either her own weapons or those of Jade from previous games: a telescoping staff, and a glaive throwing blade that is guidable in midflight
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Dictionary of American Regional English These resources included historical and contemporary newspapers, diaries, letters, histories, biographies, novels, and government documents. A number of important unpublished collections of dialect materials were also donated to "DARE" for use in documenting the "Dictionary" entries. As the fieldworkers sent their questionnaires back to Madison, the approximately 2.3 million answers were keypunched, and software was written to create a question-by-question tabulation of responses as well as an index. In addition, programs were written that allowed the interactive creation of maps showing where the responses were found and the production of statistical tables itemizing the age, sex, race, education level, and community type for each person who gave a particular response. These tools allow "DARE" editors to apply regional labels to entries based on where words were collected in the fieldwork project and to use social labels describing individuals who use those words. In 1974, Cassidy contracted with Harvard University Press to publish the Dictionary, and editing began in earnest in 1975. By 1980 it was clear that the idea of writing and publishing "DARE" as a single unit was impossible. Early estimates of the time it would take to write and revise entries had been overly optimistic. Following the tradition of other historical dictionaries such as the "Oxford English Dictionary", "DARE" decided to publish each volume as it was ready
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Consignee It is helpful to give and take the information about to be paid and received. It helps to settle dispute as it includes the detail about the goods and terms of trade and payment. It informs the selling price to the consignee. It helps to know the quality , the quantity, the price and the discount to the importer.
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Haptic memory This means that areas close on the body surface receive nervous signals from areas that are close together on the brain surface. Several distinct areas of the parietal lobe are responsible for contributing to different aspects of haptic memory. Memory for the properties of stimuli such as roughness, spatial density, and texture involves activation of the parietal operculum. Properties of stimuli such as size and shape, as detected by touch receptors in the skin, are stored in the anterior part of the parietal lobe. Memory for spatial information such as the location of stimuli involves the right superior parietal lobule and temporoparietal junction. Additional neuroimaging data has been provided by studies using microelectrodes implanted in the somatosensory cortex of monkeys. When performing a delayed match to sample task with objects of identical dimensions but different surface features, activity is observed in somatosensory neurons during perception and in the short-term memory for tactile stimuli. According to a study done by Bruce V. DiMattia, Keith A. Posley and Joaquin M. Fuster, it was found that monkeys were quite capable of concurrent Visual-to-Haptic as well as Haptic-to-Visual crossmodal matching of objects by size, shape and texture. It was also discovered that they were more adept at performing cross modal matching in the Visual-to-Haptic direction. Memory is important in infancy as it forms the basis for more complex procedures such as learning and reasoning
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Phaistos Disc According to a report in "The Times" the date of manufacture has never been established by thermoluminescence. In his 2008 review, Robinson does not endorse the forgery arguments, but argues that "a thermoluminescence test for the is imperative. It will either confirm that new finds are worth hunting for, or it will stop scholars from wasting their effort." A gold signet ring from Knossos (the Mavro Spilio ring), found in 1926, contains a Linear A inscription developed in a field defined by a spiral—similar to the Phaistos Disc. A sealing found in 1955 shows the only known parallel to sign 21 (𐇤, the "comb") of the Phaistos disc. This is considered as evidence that the is a genuine Minoan artifact. Yves Duhoux (1977) dates the disc to between 1850 B.C. and 1600 B.C. (MMIII) on the basis of Luigi Pernier's report, which says that the Disc was in a Middle Minoan undisturbed context. Jeppesen (1963) dates it to after 1400 (LMII-III). Doubting the viability of Pernier's report, Louis Godart (1990) resigns himself to admitting that archaeologically, the disc may be dated to anywhere in Middle or Late Minoan times (MMI-LMIII, a period spanning most of the second millennium B.C.). J. Best suggests a date in the first half of the fourteenth century B.C. (LMIIIA) based on his dating of tablet PH 1. The inscription was apparently made by pressing hieroglyphic "seals" into the soft clay, in a clockwise sequence spiraling toward the center of the disk. It was then fired at high temperature
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Admittance parameters For port "n", the associated Y-parameter definition is in terms of the port voltage and port current, formula_1 and formula_2 respectively. For all ports the currents may be defined in terms of the Y-parameter matrix and the voltages by the following matrix equation: where Y is an "N" × "N" matrix the elements of which can be indexed using conventional matrix notation. In general the elements of the Y-parameter matrix are complex numbers and functions of frequency. For a one-port network, the Y-matrix reduces to a single element, being the ordinary admittance measured between the two terminals. The Y-parameter matrix for the two-port network is probably the most common. In this case the relationship between the port voltages, port currents and the Y-parameter matrix is given by: where For the general case of an "N"-port network, The input admittance of a two-port network is given by: where Y is the admittance of the load connected to port two. Similarly, the output admittance is given by: where Y is the admittance of the source connected to port one. The Y-parameters of a network are related to its S-Parameters by and where formula_12 is the identity matrix, formula_13 is a diagonal matrix having the square root of the characteristic admittance (the reciprocal of the characteristic impedance) at each port as its non-zero elements, formula_14 and formula_15 is the corresponding diagonal matrix of square roots of characteristic impedances
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Steam power during the Industrial Revolution The steam once admitted into the cylinder was first condensed by an external cold water spray, thus creating a partial vacuum which drew water up through a pipe from a lower level; then valves were opened and closed and a fresh charge of steam applied directly on to the surface of the water now in the cylinder, forcing it up an outlet pipe discharging at higher level. The engine was used as a low-lift water pump in a few mines and numerous water works, but it was not a success since it was limited in pumping height and prone to boiler explosions. The first practical mechanical steam engine was introduced by Thomas Newcomen in 1712. Newcomen apparently conceived his machine quite independently of Savery, but as the latter had taken out a very wide-ranging patent, Newcomen and his associates were obliged to come to an arrangement with him, marketing the engine until 1733 under a joint patent. Newcomen's engine appears to have been based on Papin's experiments carried out 30 years earlier, and employed a piston and cylinder, one end of which was open to the atmosphere above the piston
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Nuclear magnetic resonance Thus, a nucleus with a long "T" relaxation time gives rise to a very sharp NMR peak in the FT-NMR spectrum for a very homogeneous ("well-shimmed") static magnetic field, whereas nuclei with shorter "T" values give rise to broad FT-NMR peaks even when the magnet is shimmed well. Both "T" and "T" depend on the rate of molecular motions as well as the gyromagnetic ratios of both the resonating and their strongly interacting, next-neighbor nuclei that are not at resonance. A Hahn echo decay experiment can be used to measure the dephasing time, as shown in the animation below. The size of the echo is recorded for different spacings of the two pulses. This reveals the decoherence which is not refocused by the 180° pulse. In simple cases, an exponential decay is measured which is described by the "T" time. NMR spectroscopy is one of the principal techniques used to obtain physical, chemical, electronic and structural information about molecules due to the chemical shift of the resonance frequencies of the nuclear spins in the sample. Peak splittings due to J- or dipolar couplings between nuclei are also useful. NMR spectroscopy can provide detailed and quantitative information on the functional groups, topology, dynamics and three-dimensional structure of molecules in solution and the solid state. Since the area under an NMR peak is usually proportional to the number of spins involved, peak integrals can be used to determine composition quantitatively
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Muscarinic acetylcholine receptor Here acetylcholine is again used as a neurotransmitter, and "muscarinic" receptors form the principal receptors on the innervated tissue. Very few parts of the sympathetic system use cholinergic receptors. In sweat glands the receptors are of the "muscarinic" type. The sympathetic nervous system also has some preganglionic nerves terminating at the chromaffin cells in the adrenal medulla, which secrete epinephrine and norepinephrine into the bloodstream. Some believe that chromaffin cells are modified postganglionic CNS fibers. In the adrenal medulla, acetylcholine is used as a neurotransmitter, and the receptor is of the "nicotinic" type. The somatic nervous system uses a nicotinic receptor to acetylcholine at the neuromuscular junction. Muscarinic acetylcholine receptors are also present and distributed throughout the local nervous system, in post-synaptic and pre-synaptic positions. There is also some evidence for postsynaptic receptors on sympathetic neurons allowing the parasympathetic nervous system to inhibit sympathetic effects. It is known that muscarinic acetylcholine receptors also appear on the pre-synaptic membrane of somatic neurons in the neuro-muscular junction, where they are involved in the regulation of acetylcholine release. Muscarinic acetylcholine receptors belong to a class of metabotropic receptors that use G proteins as their signaling mechanism
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The Conversation (Mad About You) Jamie and Paul Buchman put their infant daughter Mabel to bed, and wait outside the bedroom door to see if she will go to sleep on her own. Jamie sets a timer for intervals that allow them to check on Mabel, but they can only comfort her verbally. Paul is unhappy with the method, as he wants to go in and hold Mabel, but Jamie insists that it will be good for her in the end, and stops him from going into the room early. As they wait outside the door, Paul and Jamie talk about various topics, including Jamie winning 500 pounds of rigatoni, Paul's concern that he is shrinking and his sudden realization that they have a cabinet by the room. When Jamie discovers their dog Murray is in the bedroom, Paul has to crawl in and get Murray out. Paul picks up a magazine featuring a sales listing for a house, and he admits that he wants to move to the suburbs. Paul and Jamie argue over city and suburban living, causing Jamie to remark that they are completely incompatible as parents, as they disagree on almost everything. Jamie feels sick and Paul helps her to realize that her gut instinct is telling her to pick up Mabel. However, just before they go in, they hear that Mabel has finally fallen asleep. Jamie tells Paul that they broke Mabel's heart because she knows that they will not always be there for her. Paul stops Jamie from going inside, as he worries that they will wake her. Jamie then tells him to turn back the clock and they stay outside the door
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Liverpool Cenotaph stands on St George's Plateau, to the east of St George's Hall in Liverpool, England. It was erected as a memorial to those who had fallen in the First World War. The dates of the Second World War were subsequently added. The cenotaph consists of a rectangular block of stone on a stone platform, with bronze, low-relief sculptures on the sides depicting marching troops and mourners. It was designed by Lionel Budden, with carving by Herbert Tyson Smith. Initially designated as a Grade II listed building, its status was raised to Grade I in 2013. In 1926, a competition was held to create a memorial using public funds, with Charles Reilly, professor of architecture at the University of Liverpool, as assessor. There were 257 entrants; the winning, anonymised entry was by Reilly's assistant, Lionel Budden. The building contractors appointed were A. E. Bradley and Company, the sculptor was Herbert Tyson Smith, and his bronze sculptures were made at the foundry of the Morris-Singer Company. The cenotaph was unveiled at 11 am on 11 November 1930 by the 17th Earl of Derby. Following the end of the Second World War, the dates 1939 and 1945 were added. These were unveiled on Remembrance Sunday, 10 November 1946, by William G. Gregson, Lord Mayor of Liverpool. The cenotaph consists of a rectangular block of Stancliffe stone, with bronze relief statues on the sides, standing on a platform of Yorkshire Silex stone. The rectangular block is long and high, the length of the bronze panels is , and the platform is long and deep
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Infradian rhythm In chronobiology, an infradian rhythm is a rhythm with a period longer than the period of a circadian rhythm, i.e., with a frequency less than one cycle in 24 hours, such as menstruation, breeding, tidal or seasonal rhythms. In contrast, ultradian rhythms have periods shorter than the period of a circadian rhythm. Several infradian rhythms are known to be caused by hormone stimulation or exogenous factors. For example, seasonal depression, an example of an infradian rhythm occurring once a year, can be caused by the systematic lowering of light levels during the winter.
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Alisporivir (INN), or Debio 025, DEB025, (or UNIL-025) is a cyclophilin inhibitor. Its structure is reminiscent of, and synthesized from ciclosporin. It inhibits cyclophilin A. is not immunosuppressive. It is being researched for potential use in the treatment of hepatitis C. It has also been investigated for Duchenne muscular dystrophy. is under development by Debiopharm for Japan and by Novartis for the rest of the world (licence granted by Debiopharm) since February 2010.
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Multiculturalism English was established as the medium of instruction in schools during the 1960s and 1970s and is the language of trade and government while the other three languages are taught as second languages ("mother tongues"). Besides being a multilingual country, Singapore also acknowledges festivals celebrated by the three main ethnic communities. During British colonial rule, ethnic enclaves such as Geylang, Chinatown, and Little India were enforced. Presently , remnants of colonial ethnic concentration still exist but housing in Singapore is governed by the Ethnic Integration Policy, which ensures an even ethnic distribution throughout Singapore. A similar policy exists in politics as all Group Representation Constituencies are required to field at least one candidate from an ethnic minority. South Korea remains a relatively homogenous country ethnically, linguistically, and culturally. Foreigners, expatriates, and immigrants are often rejected by the mainstream South Korean society and face discrimination. However, the word "multiculturalism" is increasingly heard in South Korea
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Digital leisure studies The digital turn signifies a new period in leisure scholarship and demands a conceptual change, one in which leisure scholars turn to new resources and ways of capturing what digitization means for our lives and leisure Redheadnoted, leisure scholars “need to produce sustained theorizing of the “digital turn” in Leisure Studies and with it more satisfactory theoretically informed empirical studies of digital leisure cultures” (p. 828) to engage in broader scholarly conversations. To do so, it has been suggested leisure scholars shift the ways they are thinking about leisure and draw on different disciplines and theories as resources to begin to shape digital leisure theory and theorizing. For example, Redhead has recommended that digital leisure theory be shaped by critical theory and critical theorists from other disciplines such as philosophers, including Braudrillard, Badiou, Zizek, and Virilio. Redhead presented two concepts to guide digital leisure theory: accelerated culture and claustropolitanism. Karl Spracklen has presented a theory of communicative and instrumental digital leisure drawing on theorists such as Habermas, Catells, Urry, and Bauman. He argued that digital leisure is more communicative given its possibilities for interactivity and resisting power disparities, but despite these possibilities, it is not immune to instrumental structures that shape traditional (non-digitized) popular leisure
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Elizabethan era The is the epoch in the Tudor period of the history of England during the reign of Queen Elizabeth I (1558–1603). Historians often depict it as the golden age in English history. The symbol of Britannia (a female personification of Great Britain) was first used in 1572, and often thereafter, to mark the Elizabethan age as a renaissance that inspired national pride through classical ideals, international expansion, and naval triumph over Spain. The historian John Guy (1988) argues that "England was economically healthier, more expansive, and more optimistic under the Tudors" than at any time in a thousand years. This "golden age" represented the apogee of the English Renaissance and saw the flowering of poetry, music and literature. The era is most famous for theatre, as William Shakespeare and many others composed plays that broke free of England's past style of theatre. It was an age of exploration and expansion abroad, while back at home, the Protestant Reformation became more acceptable to the people, most certainly after the Spanish Armada was repelled. It was also the end of the period when England was a separate realm before its royal union with Scotland. The Elizabethan age contrasts sharply with the previous and following reigns. It was a brief period of internal peace between the English Reformation and the religious battles between Protestants and Catholics and then the political battles between parliament and the monarchy that engulfed the remainder of the seventeenth century
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Towpath A towpath is a road or trail on the bank of a river, canal, or other inland waterway. The purpose of a towpath is to allow a land vehicle, beasts of burden, or a team of human pullers to tow a boat, often a barge. This mode of transport was common where sailing was impractical due to tunnels and bridges, unfavourable winds, or the narrowness of the channel. After the Industrial Revolution, towing became obsolete when engines were fitted on boats and when railway transportation superseded the slow towing method. Since then, many of these towpaths have been converted to multi-use trails. They are still named towpaths — although they are now only occasionally used for the purpose of towing boats. Early inland waterway transport used the rivers, and while barges could use sails to assist their passage when winds were favourable or the river was wide enough to allow tacking, in many cases this was not possible, and gangs of men were used to bow-haul the boats. As river banks were often privately owned, such teams worked their way along the river banks as best they could, but this was far from satisfactory. On British rivers such as the River Severn, the situation was improved by the creation of towing path companies in the late 1700s. The companies built towing paths along the banks of the river, and four such companies improved a section of in this way between Bewdley and Coalbrookdale
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Khanty language The demonstrative pronouns and adjectives are: Basic interrogative pronouns are: Khanty numerals, compared with Hungarian and Finnish, are: The formation of multiples of ten shows Slavic influence in Khanty, whereas Hungarian uses the collective derivative suffix "-van (-ven)" closely related to the suffix of the adverbial participle which is "-va (-ve)" today but used to be "-ván (-vén)". Note also the regularity of "house" and "hundred". Both Khanty and Mansi are basically nominative–accusative languages but have innovative morphological ergativity. In an ergative construction, the object is given the same case as the subject of an intransitive verb, and the locative is used for the agent of the transitive verb (as an instrumental) . This may be used with some specific verbs, for example "to give": the literal Anglicisation would be "by me (subject) a fish (object) gave to you (indirect object)" for the equivalent of the sentence "I gave a fish to you". However, the ergative is a morphological (marked using a case) only, not syntactic, so that, in addition, these may be passivized in a way resembling English. For example, in Mansi, "a dog (agent) bit you (object)" could be reformatted as "you (object) were bitten, by a dog (instrument)". Khanty is an agglutinative language and employs an SOV order. The lexicon of the Khanty varieties is documented relatively well. The most extensive early source is Toivonen (1948), based on field records by K. F. Karjalainen from 1898–1901
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Problem of evil Gottfried Leibniz introduced the term theodicy in his 1710 work "Essais de Théodicée sur la bonté de Dieu, la liberté de l'homme et l'origine du mal" ("Theodicic Essays on the Benevolence of God, the Free will of man, and the Origin of Evil") which was directed mainly against Bayle. He argued that this is the best of all possible worlds that God could have created. Imitating the example of Leibniz, other philosophers also called their treatises on the problem of evil theodicies. Voltaire's popular novel "Candide" mocked Leibnizian optimism through the fictional tale of a naive youth. The population and economic theorist Thomas Malthus stated in a 1798 essay that people with health problems or disease are not suffering, and should not viewed as such. Malthus argued, "Nothing can appear more consonant to our reason than that those beings which come out of the creative process of the world in lovely and beautiful forms should be crowned with immortality, while those which come out misshapen, those whose minds are not suited to a purer and happier state of existence, should perish and be condemned to mix again with their original clay. Eternal condemnation of this kind may be considered as a species of eternal punishment, and it is not wonderful that it should be represented, sometimes, under images of suffering
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Woody plant Winter buds are formed when the dormant season begins. Depending on the plant, these buds contain either new leaf growth, new flowers, or both. Terminal buds have a stronger dominance on conifers than broadleaf plants, thus conifers will normally grow a single straight trunk without forking or large side or lateral branches. As a woody plant grows, it will often lose lower leaves and branches as they become shaded out by the canopy. If a given stem is producing an insufficient amount of energy for the plant, the roots will "abort" it by cutting off the flow of water and nutrients, causing it to gradually die. Below ground, the root system expands each growing season in much the same manner as the stems. The roots grow in length and send out smaller lateral roots. At the end of the growing season, the newly-grown roots become woody and cease future length expansion, but will continue to expand in diameter. However, unlike the above-ground portion of the plant, the root system continues to grow, although at a slower rate, throughout the dormant season. In cold-weather climates, root growth will continue as long as temperatures are above 36°F (2°C). Wood is primarily composed of xylem cells with cell walls made of cellulose and lignin. Xylem is a vascular tissue which moves water and nutrients from the roots to the leaves
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Ancient Egyptian pottery From that point of view it was less about social stratification than about a stratification of the value which people attach to things. It would therefore be wrong to say that Egyptian potters were despised. There was a strong sense that the process was a creative one. Thus, the word for 'potter' ("qd") is the same one used for 'building' walls and structures. Even the activities of creator gods were depicted using the image of the potter. The ram-headed creator god Khnum was shown creating gods, men, animals and plants on the potter's wheel. This suggests high esteem for ceramic production. Stephan Seidlmayer investigated the social and organisational circumstances of pottery production in the transitional period from the Old Kingdom to the Middle Kingdom, asking how the archaeological evidence can be connected to the image of the historical situation which we have built up from other sources. He concludes that the economic situation in the Old Kingdom favoured a centralised, standardised, and specialised production in great quantities, using complicated procedures. The organisational capacity of the state enabled focused production with high-quality pottery suitable for storage and transport in the context of the extensive distribution of goods by a centralised system. In the late Old Kingdom and the First Intermediate period, the centralised system deteriorated. It was replaced by decentralised production in small quantities for the circulation of goods within relatively small areas
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Test suite An executable test suite works on a sufficiently detailed level to correctly communicate with the SUT and a test harness is usually present to interface the executable test suite with the SUT. A test suite for a primality testing subroutine might consist of a list of numbers and their primality (prime or composite), along with a testing subroutine. The testing subroutine would supply each number in the list to the primality tester, and verify that the result of each test is correct.
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Photolithography This water repellent layer prevents the aqueous developer from penetrating between the photoresist layer and the wafer's surface, thus preventing so-called lifting of small photoresist structures in the (developing) pattern. In order to ensure the development of the image, it is best covered and placed over a hot plate and let it dry while stabilizing the temperature at 120 °C. The wafer is covered with photoresist by spin coating. Thus, the top layer of resist is quickly ejected from the wafer's edge while the bottom layer still creeps slowly radially along the wafer. In this way, any 'bump' or 'ridge' of resist is removed, leaving a very flat layer. Final thickness is also determined by the evaporation of liquid solvents from the resist. For very small, dense features (< 125 or so nm), lower resist thicknesses (< 0.5 microns) are needed to overcome collapse effects at high aspect ratios; typical aspect ratios are < 4:1. The photo resist-coated wafer is then prebaked to drive off excess photoresist solvent, typically at 90 to 100 °C for 30 to 60 seconds on a hotplate. A BARC coating (Bottom Anti-Reflectant Coating) may be applied before the photoresist is applied, to avoid refections from occurring under the photoresist and to improve the photoresist's performance at smaller semiconductor nodes. After prebaking, the photoresist is exposed to a pattern of intense light
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Jand (Transoxania) Jand (also Jend), was a medieval town on the right bank of the lower Jaxartes river in Transoxiana. It was the winter capital of Seljuk power before their migration to Khurasan, and was ruined by the Mongols, and is now a decayed village.
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Philosophy of mind Physicalistic monism asserts that the only existing substance is physical, in some sense of that term to be clarified by our best science. However, a variety of formulations (see below) are possible. Another form of monism, idealism, states that the only existing substance is mental. Although pure idealism, such as that of George Berkeley, is uncommon in contemporary Western philosophy, a more sophisticated variant called panpsychism, according to which mental experience and properties may be at the foundation of physical experience and properties, has been espoused by some philosophers such as Alfred North Whitehead and David Ray Griffin. Phenomenalism is the theory that representations (or sense data) of external objects are all that exist. Such a view was briefly adopted by Bertrand Russell and many of the logical positivists during the early 20th century. A third possibility is to accept the existence of a basic substance that is neither physical nor mental. The mental and physical would then both be properties of this neutral substance. Such a position was adopted by Baruch Spinoza and was popularized by Ernst Mach in the 19th century. This neutral monism, as it is called, resembles property dualism. Behaviorism dominated philosophy of mind for much of the 20th century, especially the first half. In psychology, behaviorism developed as a reaction to the inadequacies of introspectionism
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Rothko case On September 16, 1968, Rothko executed a two-page will, drafted by and its execution supervised by his friend Bernard Reis, an unlicensed law-school graduate and Certified Public Accountant, leaving all of his residual estate to the non-profit Rothko Foundation which Rothko organized shortly before his death. Five months later on February 21, 1969, Rothko entered into an agreement with Marlborough A.G., a Liechtenstein corporation with international galleries, which provided in part that he agreed "not to sell any works of art for a period of eight years, except to Marlborough A.G. if a supplementary contract is made." One year later Rothko died by suicide on February 25, 1970, leaving an estate consisting primarily but not entirely of 798 of his paintings. Rothko's wife Mary Alice died of a stroke six months after her husband's demise. Rothko's will was admitted to probate the month following his death, naming his estate executors: Bernard Reis, who had drafted Rothko's will and who became a Marlborough Gallery New York director the month before Rothko died; Theodoros Stamos, a friend and fellow artist represented by Marlborough New York starting in 1971; and Morton Levine, an anthropology professor, unconnected with Marlborough but who had been Rothko's son Christopher's guardian for a short time
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Seismic noise ) but these sources are generally not used to characterize structures. The branch that studies the modal properties of systems under ambient vibrations is called Operational modal analysis (OMA) or Output-only modal analysis and provides many useful methods for civil engineering. The observed vibration properties of structures integrate all the complexity of these structures including the load-bearing system, heavy and stiff non-structural elements (infill masonry panels...), light non-structural elements (windows...) and the interaction with the soil (the building foundation may not be perfectly fixed on the ground and differential motions may happen). This is emphasized because it is difficult to produce models able to be compared with these measurements. Single-station methods: The power spectrum computation of ambient vibration recordings in a structure (e.g. at the top floor of a building for larger amplitudes) gives an estimation of its resonance frequencies and eventually its damping ratio. Transfer function method: Assuming ground ambient vibrations is the excitation source of a structure, for instance a building, the Transfer Function between the bottom and the top allows to remove the effects of a non-white input. This may particularly be useful for low signal-to-noise ratio signals (small building/high level of ground vibrations). However this method generally is not able to remove the effect of soil-structure interaction
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Fullerene Crystallization of from benzene solution below 30 °C (when solubility is maximum) yields a [[triclinic]] solid [[solvate]] ·4. Above 30 °C one obtains solvate-free [[face-centered cubic|fcc]] . In 1999, researchers from the [[University of Vienna]] demonstrated that [[wave-particle duality]] applied to molecules such as fullerene. Fullerenes are normally electrical insulators, but when crystallized with alkali metals, the resultant compound can be conducting or even superconducting. Some fullerenes (e.g. , , , and ) are [[inherent chirality|inherently chiral]] because they are D-symmetric, and have been successfully resolved. Research efforts are ongoing to develop specific sensors for their enantiomers. Two theories have been proposed to describe the molecular mechanisms that make fullerenes. The older, “bottom-up” theory proposes that they are built atom-by-atom. The alternative “top-down” approach claims that fullerenes form when much larger structures break into constituent parts. In 2013 researchers discovered that asymmetrical fullerenes formed from larger structures settle into stable fullerenes. The synthesized substance was a particular [[metallofullerene]] consisting of 84 carbon atoms with two additional carbon atoms and two [[yttrium]] atoms inside the cage. The process produced approximately 100 micrograms. However, they found that the asymmetrical molecule could theoretically collapse to form nearly every known fullerene and metallofullerene
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Autonomous robot Some of these unmanned aerial vehicles (UAVs) are capable of flying their entire mission without any human interaction at all except possibly for the landing where a person intervenes using radio remote control. Some drones are capable of safe, automatic landings, however. An autonomous ship was announced in 2014—the Autonomous spaceport drone ship—and is scheduled to make its first operational test in December 2014. Outdoor autonomy is the most difficult for ground vehicles, due to: There are several open problems in autonomous robotics which are special to the field rather than being a part of the general pursuit of AI. According to George A. Bekey's "Autonomous Robots: From Biological Inspiration to Implementation and Control", problems include things such as making sure the robot is able to function correctly and not run into obstacles autonomously. Researchers concerned with creating true artificial life are concerned not only with intelligent control, but further with the capacity of the robot to find its own resources through foraging (looking for food, which includes both energy and spare parts). This is related to autonomous foraging, a concern within the sciences of behavioral ecology, social anthropology, and human behavioral ecology; as well as robotics, artificial intelligence, and artificial life. The Seekur robot was the first commercially available robot to demonstrate MDARS-like capabilities for general use by airports, utility plants, corrections facilities and Homeland Security
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Cooling load temperature difference calculation method Depending on the properties of the building envelope, a delay is present when observing the amount of heat being transferred inside from the outdoors. The CLF is the cooling load at a given time compared to the heat gain from earlier in the day. The SC, or shading coefficient, is used widely in the evaluation of heat gain through glass and windows. Finally, the SCL, or solar cooling load factor, accounts for the variables associated with solar heat load. These include the global coordinates of the site and the size of the structure. The equations for the use of the data retrieved from these tables are very simple. Q= heat gain, usually heat gain per unit time A= surface area U= Overall heat transfer coefficient CLTD= cooling load temperature difference SCL= solar cooling load factor CLF= cooling load factor SC= shading coefficient Q = U*A*CLTD Q = U*A*(T2-T1) Where Q = Overall heat transfer in Btu per hour Q = Q*CLF Q = A*SC*SCL In addition to tables published by ASHRAE for select latitudes, a computer program called CLTDTAB, available since 1993, can be used to generate custom CLTD/CLF/SCL tables for a specific zone type for any latitude and month. This allows the use of this method, without interpolation, for any area in the world. If the program CLTDTAB is used, the results obtained using this method will tend to be very close to the more rigorous TFM Method mentioned earlier.
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Eflornithine The drug was registered for the treatment of gambiense sleeping sickness on November 28, 1990. However, in 1995 Aventis (now Sanofi-Aventis) stopped producing the drug, whose main market was African countries, because it did not make a profit. In 2001, Aventis and the WHO formed a five-year partnership, during which more than 320,000 vials of pentamidine, over 420,000 vials of melarsoprol, and over 200,000 bottles of eflornithine were produced by Aventis, to be given to the WHO and distributed by the association Médecins sans Frontières (also known as Doctors Without Borders) in countries where sleeping sickness is endemic. According to Médecins sans Frontières, this only happened after "years of international pressure," and coinciding with the period when media attention was generated because of the launch of another eflornithine-based product (Vaniqa, for the prevention of facial-hair in women), while its life-saving formulation (for sleeping sickness) was not being produced. From 2001 (when production was restarted) through 2006, 14 million diagnoses were made. This greatly contributed to stemming the spread of sleeping sickness, and to saving nearly 110,000 lives. Vaniqa is a cream, which is white to off-white in colour. It is supplied in tubes of 30 g and 60 g in Europe. Vaniqa contains 15% w/w eflornithine hydrochloride monohydrate, corresponding to 11.5% w/w anhydrous eflornithine (EU), respectively 13.9% w/w anhydrous eflornithine hydrochloride (U.S.), in a cream for topical administration
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Separate spheres NOW stressed the importance of focusing on structurally altering the family sphere in order to then create gender equality in the education and workplace spheres. The family sphere is acting as a catalyst seeing that without a change in it, women would simply lack access to the opportunities that men already have available to them. Franklin also pointed out that the gender inequality among the American population in the 60’s and 70’s was a major contributor to the civil rights statutes of the Second Reconstruction. Deborah Rotman, an anthropologist at Notre Dame, analyzed this concept of separate spheres specifically among the people of Deerfield, Massachusetts in the late nineteenth and early twentieth century. In this community, there was a clear divide between men and women by means of a “proper allocation” in which females were given the domestic residence or sphere and the men were given the “economically productive agricultural land”. Men would migrate away from the women if agriculture was depleting in their given agricultural space. As the men were moving to work outside the home, women began to acclimate to the economic atmosphere and gain more opportunities in the public sphere with all the men working elsewhere. These women soon had various roles in the public and private spheres in Deerfield
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Fire protection engineering and the University of Cincinnati offers an associate degree in Fire Science and a bachelor's degree in Fire and Safety Engineering Technology as distance learning options, the only university in the U.S. and Canada to hold this distinction. Other institutions, such as the University of Kansas, Illinois Institute of Technology, University of California, Berkeley, University of California, San Diego, Eastern Kentucky University, and the University of Texas at Austin have or do offer courses in Fire Protection Engineering or technology. Canada has fire engineering programs at York University and the University of Waterloo. The practice of final fire sprinkler systems design and hydraulic calculations is commonly performed by design technicians who are often educated in-house at contracting firms throughout North America, with the objective of preparing designers for certification by testing by associations such as NICET (National Institute for Certification in Engineering Technologies). NICET certification is commonly used as a proof of competency for securing a license to design and install fire protection systems. In Europe, the University of Edinburgh offers a degree in Fire Engineering and had its first fire research group in the 1970s. These activities are now conducted at the new BRE Centre for Fire Safety Engineering. The University of Leeds uniquely offers an MSc award in Fire "and" Explosion Engineering
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Vertical farming Bruce Bugbee claimed that the power demands of vertical farming would be uncompetitive with traditional farms using only natural light. Environmental writer George Monbiot calculated that the cost of providing enough supplementary light to grow the grain for a single loaf would be about $15. An article in the Economist argued that "even though crops growing in a glass skyscraper will get some natural sunlight during the day, it won't be enough" and "the cost of powering artificial lights will make indoor farming prohibitively expensive". Moreover, researchers determined that if only solar panels were to be used to meet the energy consumption of a vertical farm, “the area of solar panels required would need to be a factor of twenty times greater than the arable area on a multi-level indoor farm”, which will be hard to accomplish with larger vertical farms. A hydroponic farm growing lettuce in Arizona would require 15,000 kJ of energy per kilogram of lettuce produced. To put this amount of energy into perspective, a traditional outdoor lettuce farm in Arizona only requires 1100 kJ of energy per kilogram of lettuce grown. As the book by Dr. Dickson Despommier "The Vertical Farm" proposes a controlled environment, heating and cooling costs will resemble those of any other multiple story building. Plumbing and elevator systems are necessary to distribute nutrients and water. In the northern continental United States, fossil fuel heating cost can be over $200,000 per hectare
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Social rule system theory Rules are key concepts in the new institutionalism, in several variants of socio-cultural evolutionary theory, and in work in semiotics, linguistics, and philosophy on “language games”. Among the many other researchers developing and applying rule concepts in the social sciences. In general, much of the use of rule concept in the social sciences and humanities has been informal and even metaphorical, with the major exception of Chomsky. Social rule systems are used to examine all levels of human interaction. They provide more than potential constraints on action possibilities. They also generate opportunities for social actors to behave in ways that would otherwise be impossible, for instance, to coordinate with others, to mobilize and to gain systematic access to strategic resources, to command and allocate substantial human and physical resources, and to solve complex social problems by organizing collective actions. In guiding and regulating interaction, social rules give behavior recognizable, characteristic patterns, and make such patterns understandable and meaningful for those who share in the rule knowledge. On the macro-level of culture and institutional arrangements, rule system complexes are examined: language, cultural codes and forms, institutional arrangements, shared paradigms, norms and “rules of the game”
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Erewhon Revisited Twenty Years Later, Both by the Original Discoverer of the Country and by His Son (1901) is a satirical novel by Samuel Butler, forming a belated sequel to his "Erewhon" (1872). "The Cambridge History of English and American Literature" judges that it "has less of the free imaginative play of its predecessor…but, in sharp brilliance of wit and criticism, in intellectual unity and coherence, it surpasses "Erewhon"". "Erewhon", set in a thinly disguised New Zealand, ended with the escape of its unnamed protagonist from the native Erewhonians by balloon. In the sequel, narrated by his son John, we are told that our hero's name is Higgs. Higgs returns to Erewhon and meets his former lover Yram, who is now the mother of his son George. He discovers that he is now worshipped as "the Sunchild", his escape having been interpreted as an ascension into heaven, and that a church of Sunchildism has sprung up. He finds himself in danger from the villainous Professors Hanky and Panky, who are determined to protect Sunchildism from him. With George's help Higgs escapes from their clutches and returns to England. The Swiftian device of setting his satire in a fictional culture enabled Butler, as the critic Elinor Shaffer has written, "to analyse the phenomena of religion from their point of genesis, while disclaiming all responsibility for their uncanny parallels to certain known religions." It did not however make the road to publication any easier
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Love After Love (poem) "Love After Love" is a poem by Derek Walcott, included in his "Collected Poems, 1948–1984" (1986).
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Racetrack problem A racetrack problem is a specific instance of a type of race condition. A racetrack problem is a flaw in a system or process whereby the output and/or result of the process is unexpectedly and critically dependent on the sequence or timing of other events that run in a circular pattern. This problem is semantically different from a race condition because of the circular nature of the problem. The term originates with the idea of two signals racing each other in a circular motion to influence the output first. Racetrack problems can occur in electronics systems, especially logic circuits, and in computer software, especially multithreaded or distributed programs.
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List of EastEnders two-hander episodes He had let Den triumph before, because he thought he wanted a father, but even though Den had put up a good fight, he wasn't going to let him win this time. Den became enraged and asserted that his and Sharon's affair was over. He ordered Dennis to leave, but Dennis replied repeatedly that he loved Sharon. Calmly, he prepared to head home to her. Seeing that he was losing the fight Den turned angry and hurled Dennis through the doors of The Queen Vic. Father and son stood head to head, while Dennis bragged about Sharon leaving with him. Cockily, he shoved his father aside. Furious, Den spat out that some twisted pervert must have got to Dennis in the past, and caused him to think that a relationship with his own sister was acceptable. He described the abuse Dennis must have suffered in care and waved goodbye to the son he never wanted. Dennis finally snapped and lunged at him out of control, but was restrained. Eventually he broke free and lashed out, accidentally punching Sharon, who had just arrived, in the process. A victorious Den then took Sharon home. This episode featured Kat Moon (Jessie Wallace) and Alfie Moon (Shane Richie). Alfie had been given a video of Andy Hunter (Michael Higgs) sleeping with his wife, Kat. Alfie owed Andy money and when he couldn't pay he Andy threatened his safety. Kat slept with Andy as a trade for her husband's life, but Alfie could not accept her excuses
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Loghain Mac Tir Loghain was the first character to be created during the development cycle for "Origins". In an interview with "PC Gamer", "Origins" lead writer Gaider describes Loghain's characterization as part of the general shift toward a more morally ambiguous form of RPG. He explained that “a lot of "Dragon Age" was us at BioWare reacting to things we did or didn’t like about "Dungeons & Dragons" as a game system or a setting, so I’d say the effort to move to something more morally grey was intentional. Good people are capable of terribly evil things, and terrible people are capable of great good”. He said Loghain's relatable motives are an intentional design choice, allowing for the possibility that a player might be able to see from his perspective and judge him as simply being misguided. Rick Lane, writing for "PC Gamer", notes that this kind of flexibility in a villain's character and how the player can respond to it is entirely unique to the interactive nature of a video game, and commented that some developers favor deceiving players with narrative tricks as a key part of their strategy to making certain characters “feel villainous". Loghain is depicted as a war hero and a patriot, revered by many common folk in Ferelden. He inspires intense loyalty among those who serve under him
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Hydroxybenzoic acid may refer to several related chemical compounds:
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The False Friend; or, the Fate of Disobedience Heavey writes that Pix "recognised the dramatic and pathetic potential of a comparison between Medea and a scorned woman".
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Industrial fan Radial blade – The flat blades of this type are arranged in a radial pattern. These rugged fans offer high pressure capability with average efficiency. They are often fitted with erosion-resistant liners to extend rotor life. The housing design is compact to minimize the floor space requirement. Radial tipped – These fans have wheels that are backward curved, but in a way slightly different from backward curved fans. Backward curved fans have wheels whose blades curve outward, while radial-tip fans' blades are curved inward and radial at their tips (hence the name "radial tip"), while still in a backwardly-curved configuration. Their curvature can also be thought of as radial at the tips but gradually sloping toward the direction of rotation. This rugged design is used in high-volume flow rate applications when the pressure requirement is rather high and erosion resistance is necessary. It offers medium efficiencies. A common application is the dirty side of a baghouse or precipitator. The design is more compact than airfoil, backward curved or backward inclined fans. Paddle-wheel – This is an open impeller design without shrouds. Although the efficiency is not high, this fan is well suited for applications with extremely high dust loading. It can be offered with field-replaceable blade liners from ceramic tiles or tungsten carbide. This fan may also be used in high-temperature applications
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Privacy " Some experts assert that in fact the right to privacy "should not be defined as a separate legal right" at all. By their reasoning, existing laws relating to privacy in general should be sufficient. It has therefore proposed a working definition for a "right to privacy": "The right to privacy is our right to keep a domain around us, which includes all those things that are part of us, such as our body, home, property, thoughts, feelings, secrets and identity. The right to privacy gives us the ability to choose which parts in this domain can be accessed by others, and to control the extent, manner and timing of the use of those parts we choose to disclose." David Flaherty believes networked computer databases pose threats to privacy. He develops 'data protection' as an aspect of privacy, which involves "the collection, use, and dissemination of personal information". This concept forms the foundation for fair information practices used by governments globally. Flaherty forwards an idea of privacy as information control, "[i]ndividuals want to be left alone and to exercise some control over how information about them is used". Richard Posner and Lawrence Lessig focus on the economic aspects of personal information control. Posner criticizes privacy for concealing information, which reduces market efficiency. For Posner, employment is selling oneself in the labour market, which he believes is like selling a product. Any 'defect' in the 'product' that is not reported is fraud
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Mozi His conversations with other renowned philosophers of that era are also recorded. From them, we can distinguish Mohism from other schools of thought more clearly. Mohism was suppressed under the Qin and died out completely under the Han, which made Confucianism the official doctrine. However, many of its ideas were dissolved into the mainstream of Chinese thought, since both Confucians such as Xunzi and Taoists such as Zhuangzi expressed sympathy with Mozi's concerns. The influence of is still visible in many Han works written hundreds of years later. In modern times, Mohism was given a fresh analysis. Sun Yat-Sen used "universal love" as one of the foundations for his idea of Chinese democracy. More recently, Chinese scholars under Communism have tried to rehabilitate as a "philosopher of the people", highlighting his rational-empirical approach to the world as well as his "proletarian" background. Some views claim that Mozi's philosophy was at once more advanced and less so than that of Confucius. His concept of "universal love" embraced a broader idea of human community than that of the Confucians, but he was less tolerant than Confucius in his condemnation of all that is not directly "useful", neglecting the humanizing functions of art and music. Zhuangzi, who criticized both the Confucians and the Mohists, had this in mind in his parables on the "usefulness of the useless"
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Hockey Night in Canada However, due to their decline in popularity, outdoor games are no longer shown on CBC or branded "HNIC" unless a Canadian team is involved. CBC also provides extensive Stanley Cup playoff coverage every spring with a focus on Canadian teams. They also have exclusive English-language rights to the Stanley Cup Finals. While its playoff coverage and rights to the Finals will continue under the Rogers sublicensing agreement, coverage will be shared with Sportsnet. For years, all playoff games involving Canadian teams were aired by the CBC, though not always on a national basis. From 2008 through 2014, rights to individual series were instead picked using a draft-like setup; in the first round, CBC first, second, fourth, and sixth selections among opening round series, and TSN had the third, fifth, seventh, and eighth selections. CBC tended to select series involving at least one Canadian team and series involving teams with strong Canadian fanbases (such as Boston, Buffalo, Detroit, and Pittsburgh); as a result of this arrangement, if more than two Canadian teams qualified for the playoffs, it was likely that at least one series involving a Canadian team would be broadcast by TSN. During the first three rounds of the playoffs, the NHL usually gives higher priority to NBC's requests to schedule afternoon games on the weekends, which results in little or no post-season contests on Saturday nights
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Imaginary audience Examples of imaginary audience: A teen that is affected by imaginary audience might be self-conscious and may worry about what other people think of them. They may change their clothes constantly before leaving the house to make sure they are presentable for everybody that is watching them. They may also spend extra time on make-up and hair to better appeal to the audience they feel they need to impress. A teen may also change their wardrobe to match "trends" that start. They may also believe that they are better than everyone else and everyone is constantly looking at them and judging, feeling the need to look "perfect". A teen who has a pimple on their face will think that everyone will notice and that it is covering half of their face. (This is one very common example of imaginary audience.) In reality, only a small percentage of those people have any interest in a person’s activities, and a maturing worldview will usually reduce the impression that this imaginary audience exists. Some people, however, maintain this misapprehension well into their adult years. Gerald Adams and Randy Jones conducted a study to test imaginary audience behavior. They tested total of 115 male and female adolescents between the ages of 11 to 18 using an empathy scale, social sensitivity scale, and a measure of social desirability. They stated is seen most in teens going through puberty where their bodies are changing rapidly and they are concerned with how everyone is viewing their change
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Modern Greek grammar Its use is either as a canonical adjective, or as a part of a second, alternative perfect periphrasis with transitive verbs. Finally, there is another invariant form, formed from the present tense and typically ending in "-ontas", which is variably called either a participle or a gerund by modern authors. It is historically derived from an old present participle, and its sole use today is to form non-finite adjunct adverbial clauses of time or manner, roughly corresponding to an "-ing" participle in English. The tables below exemplify the range of forms with those of one large inflectional class of verbs, the 1st Conjugation. Below are the corresponding forms of two subtypes of another class, the 2nd conjugation. Only the basic forms are shown here; the periphrastic combinations are formed as shown above. While the person-number endings are quite regular across all verbs within each of these classes, the formation of the two basic stems for each verb displays a lot of irregularity and can follow any of a large number of idiosyncratic patterns. The use of the past tense prefix ("e-"), the so-called augment, shows some variation and irregularity between verb classes. In regular (demotic) verbs in standard modern Greek, the prefix is used depending on a stress rule, which specifies that each past tense verb form has its stress on the third syllable from the last (the "antepenultimate"); the prefix is only inserted whenever the verb would otherwise have fewer than three syllables
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Goethe Award for Psychoanalytic and Psychodynamic Scholarship The is given annually by the Section on Psychoanalytic and Psychodynamic Psychology of the Canadian Psychological Association. The award is given for the best psychoanalytic book published within the past two years and is juried by a peer review process and awards committee. In 1930, Freud was awarded the Goethe Prize of the City of Frankfurt for his literary and recognized scientific achievements. The Goethe Award Award for Psychoanalytic and Psychodynamic Scholarship was named in honour of this event. The Goethe Award was first given by the Section in 2001 and considers any disciplinary or interdisciplinary subject matter in theoretical, clinical, or applied psychodynamic or psychoanalytic psychology and is judged on the basis of providing an outstanding contribution to the field.
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Rocco Buttiglione The People's Party had presented itself along with "Patto Segni" in the centrist alliance Pact for Italy, in which it came third after Silvio Berlusconi's centre-right Pole of Freedoms/Pole of Good Government and the centre-left Alliance of Progressives. Buttiglione eventually joined forces with Berlusconi and the Northern League, led by Umberto Bossi, to win the 2001 election. Buttiglione was elected a Parliamentary Deputy for Milan in May 2001, and joined Berlusconi's new government as the European Union Policy Minister. From 2005-06 Buttiglione was Minister for Cultural Assets and Activities. Following an increase of popular support for his socially conservative Catholic political party, the Union of Christian and Centre Democrats (UDC), at a time of political difficulty for Silvio Berlusconi's government, the UDC leader, Marco Follini, asked for more influence in the government. At this point the UDC was lobbying against the powerful Economy Minister Giulio Tremonti, supported by Umberto Bossi's Northern League; Subsequently, Tremonti was ousted from office and replaced with the politically more neutral Domenico Siniscalco. The new balance of power inside the ruling coalition effectively entitled the UDC to ask for even more and it was therefore decided that Rocco Buttiglione, already a minister in the government, would become Italy's member of the European Commission. As a result, his place in the Italian government was granted to another member of the UDC
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Sell your cloak and buy a sword is an instruction, by Jesus to his disciples during the Last Supper, which has been interpreted in several ways. Christian anarchist Jacques Ellul and Christian pacifist John Howard Yoder do not believe Luke 22:36 overturns the many times Jesus urged his followers to turn the other cheek and when confronted by violence during his Sermon on the Mount and years of ministry. They show when the passage is taken in context (Luke 22:36-38), Jesus is also aware of fulfilling prophecy and makes a surprising statement that two swords are "enough." Ellul, Yoder and Archie Penner claim that two swords could not possibly have been "enough" to defend Jesus from his pending arrest, trial and execution, so their sole purpose must have been Jesus' wish to fulfill a prophecy (Isaiah 53:9-12). As Ellul explains: This theory is further substantiated by Peter when Peter draws one of the swords a few hours later at Jesus' arrest in the Garden of Gethsemane, slashing the ear of Malchus, one of the priests' servants, and Jesus rebukes him saying: "Put up again thy sword into his place: for all they that take the sword shall perish with the sword."(Matthew 26:52) Jamieson, Fausset and Brown, in their 1871 biblical commentary, indicate "...And He said to them, It is enough - not 'Two swords will suffice,' but 'Enough of this for the present'
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Game theory Hurwicz introduced and formalized the concept of incentive compatibility. In 2012, Alvin E. Roth and Lloyd S. Shapley were awarded the Nobel Prize in Economics "for the theory of stable allocations and the practice of market design". In 2014, the Nobel went to game theorist Jean Tirole. A game is "cooperative" if the players are able to form binding commitments externally enforced (e.g. through contract law). A game is "non-cooperative" if players cannot form alliances or if all agreements need to be self-enforcing (e.g. through credible threats). Cooperative games are often analyzed through the framework of "cooperative game theory", which focuses on predicting which coalitions will form, the joint actions that groups take, and the resulting collective payoffs. It is opposed to the traditional "non-cooperative game theory" which focuses on predicting individual players' actions and payoffs and analyzing Nash equilibria. Cooperative game theory provides a high-level approach as it describes only the structure, strategies, and payoffs of coalitions, whereas non-cooperative game theory also looks at how bargaining procedures will affect the distribution of payoffs within each coalition
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Mistress of Mellyn was the first Gothic romance novel written by Eleanor Hibbert under the pen name "Victoria Holt". A young woman, Martha Leigh, is hired as a governess by Connan TreMellyn, a widower, for his daughter, Alvean. Martha travels to Cornwall and becomes fascinated by her employer and his dead wife. While struggling with her increasingly romantic feeling towards Connan TreMellyn, Martha also tries to solve the mystery of his wife's death in the haunted mansion while trying to avoid death herself. Set in 19th century England, "Mistress of Mellyn" weaves together elements from earlier Gothic novels such as "Jane Eyre" (1847), "The Woman in White" (1859), and "Rebecca" (1938) - a young, impressionable girl meets a mysterious widower in a mansion filled with the memories of his first wife who has suffered a tragic death. The romance between the young governess and her handsome employer is hampered by the mystery surrounding the tragic death of his first wife. Looking to solve the mystery, the young woman starts poking around the gloomy corners of the spooky mansion set on the wild Cornish cliffs. The novel was published by Doubleday in the United States and Collins in the United Kingdom. The novel was serialized in the "Ladies' Home Journal", chosen as a Reader's Digest condensed book and issued in a treasury volume that included other Gothic authors such as Daphne du Maurier, Phyllis A. Whitney, Evelyn Anthony, Madeleine Brent and Jessica Nelson North. Several reprints were issued over the years
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Basil Mott Sir Basil Mott, 1st Baronet FRS (16 September 1859 – 7 September 1938) was one of the most notable English civil engineers of the late 19th and early 20th centuries. He was responsible for some of the most innovative work on tunnels and bridges in the United Kingdom in the 40-year period centred on World War I. was born in Leicester on 16 September 1859. He was educated at the International School, Switzerland and at the Royal School of Mines where he won the Murchison medal in 1879. He was first employed as a mining engineer with the Neston Colliery Co. in Cheshire but in 1886 was invited by J H Greathead to join the staff of the City & South London Railway (C&SLR), for which Greathead was Engineer. His work on the C&SLR gave him a taste for underground construction works that influenced the remaining 40 years of his professional life. He did well at the C&SLR and was promoted, first to resident engineer (RE) for the extension of the C&SLR from Stockwell to Clapham, then to RE for the entire line. After the railway opened in 1890, he was retained as Engineer by the operating company: this gave him the opportunity to develop techniques for carrying out reconstruction works during overnight possessions of the tunnels, techniques which are still used on LU today. Shortly after Greathead's death in October 1896, Benjamin Baker formed a partnership with Mott for the design of the Central London Railway
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Gudmundur S. (Bo) Bodvarsson Gudmundur Svavar (Bo) Bodvarsson (November 11, 1952 – November 29, 2006) was an Icelandic hydrogeologist who is known for his work with the Yucca Mountain nuclear waste repository. From 1980 until his death, he was affiliated with the Berkeley Lab, serving as the director of its earth science division from 2001. He was also a prolific writer on the subject of hydrology.
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Libido Erectile dysfunction may happen to the penis because of lack of sexual desire, but these two should not be confused. For example, large recreational doses of amphetamine or methamphetamine can simultaneously cause erectile dysfunction and significantly increase libido. However, men can also experience a decrease in their libido as they age. The American Medical Association has estimated that several million US women suffer from a female sexual arousal disorder, though arousal is not at all synonymous with desire, so this finding is of limited relevance to the discussion of libido. Some specialists claim that women may experience low libido due to some hormonal abnormalities such as lack of luteinising hormone or androgenic hormones, although these theories are still controversial. Also, women commonly lack sexual desire in the period immediately after giving birth. Moreover, any condition affecting the genital area can make women reject the idea of having intercourse. It has been estimated that half of women experience different health problems in the area of the vagina and vulva, such as thinning, tightening, dryness or atrophy. Frustration may appear as a result of these issues and because many of them lead to painful sexual intercourse, many women prefer not having sex at all. Surgery or major health conditions such as arthritis, cancer, diabetes, high blood pressure, coronary artery disease or infertility may have the same effect in women
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National Schism The anathemas such as these reflected the very intense feelings that divided Greece by 1916. On the other side, feelings were just as intense. Lambros Koromilas, the Greek ambassador in Rome sent a public letter to the King stating: "The obscure and ambiguous policy which Your Governments have pursued for over a year has led us to hostilities with our natural friends, the Powers of the Entente, whom we have so frequently assures of our good friendship, whilst—the most amazing thing—this same policy has driven us to non-resistance against the Bulgarians, our hereditary enemies, when they came and captured our forts, our Macedonian towns, half our war supplies and our soldiers". At the same time (November 1916), the National Defence Army attacked the Royalist Army at Katerini aiming to capture Thessaly. This was the only battle between the armies of the two governments. After the "Noemvriana", towards the end of 1916, France and Britain, after failing to persuade the royalist government to enter the war, officially recognized the "National Defence" government as the lawful government of Greece. Ιn retaliation, the "National Defence" government and the Entente instituted a naval blockade, seized the royalist fleet and demanded the partial disarmament of the royalist forces and their withdrawal to the Peloponnese. The monarchists blamed Venizelos for having the idea of the blockade
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Tacoma Narrows Bridge (1940) The solution of such ordinary differential equation as a function of time represents the displacement response of the system (given appropriate initial conditions). In the above system resonance happens when is approximately formula_1, i.e. formula_2 is the natural (resonant) frequency of the system. The actual vibration analysis of a more complicated mechanical system—such as an airplane, a building or a bridge—is based on the linearization of the equation of motion for the system, which is a multidimensional version of equation (). The analysis requires eigenvalue analysis and thereafter the natural frequencies of the structure are found, together with the so-called "fundamental modes" of the system, which are a set of independent displacements and/or rotations that specify completely the displaced or deformed position and orientation of the body or system, i.e., the bridge moves as a (linear) combination of those basic deformed positions. Each structure has natural frequencies. For resonance to occur, it is necessary to have also periodicity in the excitation force. The most tempting candidate of the periodicity in the wind force was assumed to be the so-called vortex shedding. This is because bluff bodies (non-streamlined bodies), like bridge decks, in a fluid stream shed wakes, whose characteristics depend on the size and shape of the body and the properties of the fluid
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Quadruplex telegraph The other half of the current is sent down the wire to the remote relay and its termination load. Since the current flowing into this Y-shaped junction between the solenoids flows in opposite directions in the two local solenoids they sum to no net magnetic field and the local relay is not activated. At the remote end, the sent current flows through both solenoids in the same direction and into the termination load. Since current flows the same way in both solenoids the remote signal relay is activated by this local key. For the Diplex, a different trick is used. To send two messages simultaneously, one has two independent local telegraph keys. These are arranged so the battery is reversed in polarity on one of these. First note the challenge to overcome: the duplex solenoid as described above would not resolve which way the current is flowing. While the solenoid's magnetic field would be in the opposite direction, the induced ferromagnet in the iron bar would be attracted either way, closing the signal relay regardless of the current flow direction. The solution is to replace the iron with a permanent magnet, and the relay switch is replaced with a double pole switch. Now the permanent magnet senses the field direction and is pushed or pulled. When the permanent magnet north is repelled, the switch closes to one pole, and when the permanent magnet south is repelled the switch closes to the other pole