Split (2)

train · 7.24k rows

text stringlengths 609 7.2k	summary stringlengths 229 2k
guillain barr syndrome ( gbs ) is an acute autoimmune inflammatory demyelinating polyneuropathy that mostly affected the peripheral nervous system . gbs is clinically characterized by progressive symmetrical weakness of limbs , with or without autonomic or sensory disturbances . gbs may be induced by various factors ,...	abstractguillain barr syndrome ( gbs ) is an acute autoimmune inflammatory demyelinating polyneuropathy that mostly affects the peripheral nervous system . little is reported about spinal deformity associated with gbs . this study aims to present a case of scoliosis occurring in the setting of gbs.case report and ...
generally pediatric elbow dislocations are complex traumas that are associated with fractures around elbow , medial epicondyle avulsion fractures and median nerve injuries . the purpose of this study is to present an 8-year - old patient who has open elbow dislocation without fracture accompanying with brachial artery ...	introductionelbow dislocations in children are rare injuries . these injuries are often in the form of complex injuries that is accompanied by the median nerve damage and medial epicondyle fracture in the pediatric age group . open elbow dislocation without fracture in the pediatric age group has been reported very r...
teeth are complex anatomic structures that encounter with developmental anomaly in various aspects like defects in the structure , shape , size and number . fusion is a rare developmental anomaly with a complex morphology that can give rise to reduced esthetics , misalignment , dental caries and periodontal problems . ...	fusion is the union of two normally separated tooth germs resulting in the formation of a single large tooth . the prevalence of this anomaly is less than 1% and most common in the primary dentition , in the incisor - canine region . fusions are almost always unilateral , but few cases of bilateral fusions have bee...
iga nephropathy ( igan ) is one of the most frequent forms of glomerulonephritis ( gn ) . polycythemia can be associated with igan , focal segmental glomerulosclerosis and membranoproliferative gn . here , we report a case of idiopathic erythrocytosis in a 31-year - old male who was incidentally detected to have hypert...	we report a case of idiopathic erythrocytosis in a 31-year - old male who was incidentally detected to have hypertension during his preemployment checkup . urine routine showed proteinuria and hematuria . biochemical parameters revealed raised serum creatinine , and histological findings of the renal biopsy showed ...
angioleiomyoma is a benign soft tissue neoplasm that originates from smooth muscle in the tunica media of arteries and veins . it can occur anywhere in the body , with predilection for the lower extremity , and can be found in the dermis , subcutaneous fat , or fascia . the tumor typically presents as a painful , solit...	angioleiomyomas are benign tumors originating in the vascular smooth muscle . the tumor typically presents as painful , solitary , small ( < 2 cm ) , slow growing , subcutaneous nodule . angioleiomyoma of the knee is rare , and only few cases have been reported so far . we have described herein a giant angioleiom...
we present a case of a patient with cardiac tamponade , who presented with symptoms six weeks after the initial blunt trauma to his chest . a 63-year - old male presented to the emergency department , short of breath and feeling generally unwell for 2 days prior to admission . six weeks prior to admission , he had fall...	cardiac tamponade is a recognised complication of blunt trauma to the chest . it usually presents at the time of the acute event but there are rare cases of delayed presentations . we present such a case where the tamponade occurred six weeks following the trauma to the chest wall .
they have a tendency to recur after initial treatment , including at sites outside the bladder such as the urethra . the urethra may be the site of recurrence after previous cystectomy but occur less frequently prior to cystectomy . patients with noninvasive disease in the bladder may prefer to keep their bladders and ...	urothelial carcinoma may occur anywhere in the urinary tract including the pendulous urethra . to prevent urethral stricture after resection and monopolor fulguration we describe the use of the holmium laser to fulgurate recurrent pta uc from the urethra . the surgical approach was staged and provided excellent long ...
aneurysm formation after pancreatitis is well documented in the literature , caused by the digestion of arterial walls by the enzymes such as elastase released by the pancreas . rupture is generally considered to be a rare complication after pancreatitis , but the formation of aneurysms themselves is relatively common ...	we present a case of pancreatitis with secondary pseudoaneurysm formation in a branch of the hepatic artery , which fistulated into the common bile duct following endoscopic retrograde cholangiopancreatography . this aneurysm manifested itself clinically with recurrent haematemesis , and was treated by embolisation o...
in june 2004 , a 58-year - old asian female presented with anxiety , palpitations and breathlessness . differential leukocyte count revealed blasts , promyelocytes , myelocytes , and metamyelocytes with decreased leukocytes . liver function test ( lft ) and kidney function test ( kft ) were normal . the patient was sta...	here , we present a case of chronic myeloid leukemia for which imatinib therapy was initated . triiodothyronine ( t3 ) , thyroxine ( t4 ) , and thyroid - stimulating hormone was normal , and thyroid microsomal autoantibodies ( tma ) were positive and patient was diagnosed as thyroiditis treated with corticosteroids f...
mucous membrane pemphigoid ( mmp ) is a putative autoimmune , chronic inflammatory , subepithelial blistering disease predominantly affecting mucous membranes . mucous membranes that may be involved include the oral cavity , conjunctiva , nasopharynx , larynx , esophagus , genitourinary tract and anal canal . a 37-year...	mucous membrane pemphigoid describes a rare heterogeneous group of chronic , inflammatory , mucous membrane - dominated , subepithelial blistering diseases that manifest a varying constellation of oral , ocular , skin , genital , nasopharyngeal , esophageal , and laryngeal lesions . life - threatening airway obstruct...
gastric volvulus can be acute , acute on chronic or chronic , and may be primary or secondary to anomalies that affect the fixity of the stomach like hiatus hernia , eventration of diaphragm or congenital diaphragmatic hernia ( cdh ) . the association of bronchopulmonary foregut malformations such as congenital cystic ...	congenital diaphragmatic hernia ( cdh ) is a known cause of secondary gastric volvulus . it is also known that bronchopulmonary sequestration ( bps ) may be associated with cdh . an extremely rare case of bps associated with gastric volvulus in a girl with left sided cdh is being reported .
imatinib , a specific tyrosine kinase inhibitor has shown excellent efficacy in management of chronic myeloid leukemia ( cml ) . there may be almost complete remission hematologically in the chronic phase of management of cml due to this drug . most commonly reported adverse events are maculopapular eruptions , periorb...	imatinib , a specific tyrosine kinase inhibitor is a newer anticancer agent , which has shown excellent efficacy in managing chronic myeloid leukemia . it is generally well tolerated with few side effects . most commonly reported adverse events are maculopapular eruptions and periorbital edema . severe adverse re...
criss - cross heart ( cch ) , or superoinferior ventricles , is a complex congenital rotational abnormality in which the systemic and pulmonary venous streams cross at the atrioventricular ( av ) level without mixing . its frequency is less than 8/1000000 and accounts for < 0.1% of congenital heart defects ( chd ) . in...	crisscross heart ( cch ) is a rare cardiac malformation characterized by crossing of the inflow streams of the two ventricles due to an apparent twisting of the heart about its long axis . the developmental mechanisms and causes of cch are remaining unknown . neonates mainly presents with cyanosis and a systolic mu...
while abdominal pain is a common presentation in patients with sickle cell disease , its progression to an acute surgical abdomen is relatively rare . only a few case reports describing ischemic bowel secondary to sickle cell crisis have been published . ischemic bowel secondary to sickle cell disease has been recogniz...	we report a case of small bowel ischemia secondary to sickle cell disease . acute bowel ischemia is an uncommon presentation of patients with sickle cell disease . historically , only a handful of cases have been reported . we also provide a summary of the literature relevant to sickle cell patients with acute bo...
olanzapine is an atypical antipsychotic with efficacy in schizophrenia slightly higher than others.1 ) the extrapyramidal adverse effects are much lower than typical antipsychotics , though it has a higher metabolic adverse effect profile.2 ) orthostatic hypotension is common with first - generation antipsychotics with...	olanzapine is an atypical antipsychotic which is efficacious in the treatment of schizophrenia . the adverse effect profile for olanzapine is benign except for higher rates of metabolic events . orthostatic hypotension is less commonly reported with olanzapine as compared to first - generation and few atypical anti...
a 15-year - old female patient has been referred to the dental hospital in madurai , tamil nadu , india , with a chief complaint of missing maxillary central incisor . past dental history revealed that the patient had earlier visited a dental clinic where she had been diagnosed with a congenitally missing central incis...	impaction of maxillary permanent central incisor is not a frequently reported case in dental practice , but its treatment is challenging because of its importance to facial esthetics . early detection of such teeth is most important if complications are to be avoided . we report a case of a 14-year - old female wit...
a 70-year - old woman was admitted to hospital because of bilateral pleural effusion , and referred to our neurology department due to a 2-year history of gait disturbance that occasionally resulted in falling down , before which she had been well . six months after the first episode of falling down , her family notice...	we present a 77-year - old woman with levodopa - nonresponsive parkinsonism , dementia , and supranuclear gaze palsy on vertical and horizontal gaze . laboratory findings were consistent with idiopathic hypoparathyroidism , and brain computed tomography showed extensive bilateral calcifications of the basal ganglia ,...
what was different in pci between the two merged analysis described above?14,31 we may argue that patients treated with dess had more three - vessel disease ( 87.3% vs. 36.1% with bms ) and perhaps a higher syntax score than those treated with bms ( in fact , we will never know which was the syntax score for them ) . h...	randomized clinical trials ( rcts ) with first- and second - generation drug - eluting stents ( dess ) confirmed the superiority of coronary artery bypass surgery ( cabg ) in patients with multiple vessel disease . in spite of different des designs , investigators in these trials used similar percutaneous coronary inte...
rup has long championed public access to research articles via a six - month embargo , and we thus support this aspect of the wellcome trust policy and the new rcuk policy . however , we question the value of a provision in their policies that specifies licensing terms for reuse of content by third parties . both organ...	the existing public access policy for our three journals the journal of cell biology , the journal of experimental medicine , and the journal of general physiology is fully compliant with new policies from the research councils uk ( rcuk ) and the wellcome trust . in addition to mandating public access , the new po...
we present a case of endometriosis presenting as large bowel obstruction in a woman of childbearing age . she had no previous symptoms to suggest endometriosis and on presentation urgent surgery was required . no cases of endometriosis confined to this sigmoid colon without pelvic involvement were noted in the literatu...	introductionisolated endometriosis of the intestine causing large bowel obstruction is rare.presentation of casewe present a case of endometriosis presenting as large bowel obstruction in a woman of childbearing age . she had no previous symptoms to suggest endometriosis and on presentation urgent surgery was require...
an 85-year - old man presented with an 8-month history of slowly increasing diffuse yellow skin lesions on the torso and upper arms . he had been unaware of the discoloration until his internist noted it and referred him to dermatology . the patient had been followed by a hematologist for paraproteinemia that had not b...	diffuse normolipemic plane xanthoma ( dnpx ) was first described by altman and winkelmann in 1962 . it is a rare and non - inherited form of xanthomatosis . clinically , the dermatosis is characterized by the presence of symmetric yellowish - orange plaques that favor the neck , upper trunk , flexural folds and per...
in recent years the problem of " cutaneous ulcers " ( venous , arterial , diabetic , and pressure sores ) has become increasingly important , in particular because of the progressive increase in the elderly population and , therefore , of chronic disorders ( 1 ) . chronic cutaneous ulcers of the comorbid elderly patien...	the platelet - rich plasma ( prp ) has been advocated as a way to introduce increased concentrations of growth factors and other bioactive molecules to injured tissues in an attempt to optimize the local healing environment . a 94-yr - old woman with various comorbidities presented with a two - week history of severe c...
morvan 's syndrome is a rare autoimmune disorder characterized by peripheral nerve hyperexcitability , autonomic dysfunction , and central nervous system symptoms . the syndrome of muscle twitching , dysautonomia , insomnia , and delirium was first reported by morvan by the name of la choree fibrillare in 1890 . we rep...	morvan 's syndrome is a rare autoimmune disorder characterized by triad of peripheral nerve hyperexcitability , autonomic dysfunction , and central nervous system symptoms . antibodies against contactin - associated protein - like 2 ( caspr2 ) , a subtype of voltage - gated potassium channel ( vgkc ) complex , are fo...
the use of invasive mechanical ventilation by endotracheal intubation in acute respiratory failure is long known.1 noninvasive ventilation ( niv ) began to be considered as an alternative to invasive mechanical ventilation in acute respiratory failure caused from exacerbations of chronic obstructive pulmonary disease (...	noninvasive ventilation ( niv ) was introduced as an alternative to invasive mechanical ventilation for acute respiratory failure caused from exacerbations of chronic obstructive pulmonary disease in the 1980s , and its use gradually rose worldwide . seventy - eight patients ( 57 males , mean age 78.3 9.2 years ) un...
a 35-year - old male , diagnosed with obsessive - compulsive disorder ( ocd ) for the past 5 years was prescribed on fluoxetine up to 80 mg / day . he was receiving this treatment for the past 1 year with partial improvement of symptoms despite adequate compliance . cognitive behavior therapy was not possible due to tr...	melasma is a hyperpigmented dermatological condition common in females . drugs such as steroids , cosmetics , and photosensitizing agents are known to cause melasma . we report here a case of an adult male with obsessive - compulsive disorder , receiving clomipramine , who developed melasma .
in the previous issue of critical care nathani and colleagues have assessed kl-6 , a specific marker of type 2 alveolar epithelial cell injury , as a biomarker in acute lung injury ( ali ) . biomarkers allow identification of patients at risk of developing disease or can be used as surrogate measures for clinical outco...	studies have indicated that measuring biochemical measures of epithelial injury in plasma and alveolar fluid may be useful in predicting outcome in acute lung injury . the present commentary briefly reviews the evidence supporting the use of these biochemical biomarkers of epithelial injury in acute lung injury , and...
we review 4 patients with severe gbs and one patient with miller fisher syndrome ( mfs ) admitted to our institution from 2012 to 2013 . all patients received very high - dose ivig ( total dose of at least 4 g / kg , equivalent to 2 standard treatment courses [ 2 g / kg ] ) administered over fewer than 14 days . all pa...	objective : we describe an underrecognized side effect of high - dose iv immunoglobulin ( ivig ) , hemolytic anemia.background:there are no established guidelines on treating patients with guillain - barr syndrome ( gbs ) who relapse or do not improve after a standard course of treatment ( ivig or plasma exchange ) . ...
sertoli - leydig cell tumours ( sclts ) are rare sex - cord stromal tumors of the ovary . retiform sclt 's are rare histological variant of sclt with an average age of presentation being 16 years . to the best of our knowledge the retiform variant of sertoli leydig tumors reported so far are seen in less than 10 years ...	sertoli - leydig cell tumors are the uncommon sex - cord stromal tumors of the ovary . we report a case of 42-year - old female with retiform variant of sertoli - leydig cell tumour . she presented with the complaint of mass in abdomen for 7 years . ultrasound revealed bilateral ovarian mass suggestive of maligna...
solid pseudopapillary tumor ( spt ) of the pancreas has been variously designated as solid and cystic tumors , solid and papillary epithelial neoplasms , papillary cystic neoplasms , papillary cystic tumors , and frantz 's tumors . the world health organization renamed this tumor as spt in the international histologica...	solid pseudopapillary tumor of the pancreas is a rare tumor that affects young females with low malignant potential and good prognosis with more than 90% survival at 5 years . metastasis is very rare . we report the case of a 74-year - old female who had pancreatic solid - pseudopapillary tumor and synchronous hepa...
vaginismus is defined according to dsm iv - tr as recurrent or persistent involuntary spasm of the musculature of the outer third of the vagina , which interferes with coitus and causes distress and interpersonal difficulty . the inclusion of spasm in the definition has been questioned as it has not been consistently d...	vaginismus is defined as recurrent or persistent involuntary spasm of the musculature of the outer third of the vagina , which interferes with coitus and causes distress and interpersonal difficulty . in this report , we describe the successful treatment of vaginismus in a 25-year - old lady based on a model proposed...
she was diagnosed with subfoveal cnv secondary to age - related macular degeneration ( amd ) and the best - corrected visual acuity of the right eye was 20/50 . pdt with verteporfin was performed according to the standard protocol of the treatment of age - related macular degeneration with photodynamic therapy investig...	we report a case of serous retinal detachment following combined photodynamic therapy ( pdt ) and intravitreal bevacizumab injection in subfoveal choroidal neovascularization ( cnv).a 53-year - old woman was diagnosed with subfoveal cnv secondary to age - related macular degeneration ( amd ) and treated with combined p...
the prospective investigation conducted by fleischhackl and coworkers , reported in the previous issue of critical care , sets out to determine whether young students have the physical and cognitive skills to implement cardiopulmonary resuscitation ( cpr ) . in this investigation , the average time from the last class ...	the usefulness of basic cardiopulmonary resuscitation ( cpr ) training in school systems has been questioned , considering that young students may not have the physical or cognitive skills required to perform complex tasks correctly . in the study conducted by fleishhackl and coworkers , students as young as 9 years we...
neuroleptic malignant syndrome ( nms ) is a rare but life - threatening complication to antipsychotic agents . it was initially reported in 1960s and since then many cases have been recognized worldwide . nms is associated with a significant mortality rate and requires early recognition and prompt treatment . early dia...	neuroleptic malignant syndrome ( nms ) is a life - threatening emergency that is often seen as a complication of antipsychotic agents . it is characterized by a tetrad of motor , behavioral , autonomic , and laboratory abnormalities . we report a case of a 34-year - old man with a history of newly diagnosed type 2 ...
dense , vision - obscuring calcification on the posterior aspect of silicone intraocular lenses ( iols ) is often not amenable to neodymium : yttrium - aluminum - garnet capsulotomy , and , in prior reports , has required iol exchange . we report the successful removal of dense calcium deposition on the posterior surfa...	purposedense , vision - obscuring calcification on the posterior aspect of silicone intraocular lenses ( iols ) is often not amenable to neodymium : yttrium - aluminum - garnet capsulotomy , and , in prior reports , has required iol exchange . we report the successful removal of dense calcium deposition on the poster...
hearts , isolated from wildtype zebrafish embryos ( 24hpf to 72hpf ) were stained with the transmembrane potential - sensitive dye di-8-anepps ( invitrogen ) or the calcium - sensitive ratiometric dye fura-2 , am ( invitrogen ) for the measurements of action potentials and calcium transients , respectively . fluorescen...	electrical gradients are critical for many biological processes , including the normal function of excitable tissues , left - right patterning , organogenesis , and wound healing14 . the fundamental mechanisms that regulate the establishment and maintenance of such electrical polarities are poorly understood . using ...
a 77-year old female was referred to our clinic with a prolonged period of delayed healing following the uneventful extraction of the lower right second molar tooth in may 2007 . at this point the patient had been taking alendronic acid 70 mg orally once per week for seven years . clinical examination revealed only mi...	highlightsthis case reports the first case to our knowledge of pathological fracture of the coronoid process of the mandible secondary to long term use of alendronic acid.demonstrates the unpredictable nature of symptoms associated with medication related osteonecrosis and its management within the hospital environment...
chronic subdural hematoma ( csdh ) is a common clinical entity treated by neurosurgeons with very good cure rates . recurrence of the hematoma , infection , seizure , cerebral edema , tension pneumocephalus and failure of the brain to re - expand are well - recognized complications following surgery for csdh . an intra...	chronic subdural hematoma ( csdh ) is a common clinical entity treated by neurosurgeons with good cure rates . recurrence of the hematoma and failure of the brain to re - expand are commonly observed complications following surgery for csdh . an intracerebral or intraventricular hemorrhage following evacuation of c...
both f-18 fluorodeoxyglucose ( fdg ) and c-11 methionine pet / ct studies were done in a treated case of glioblastoma multiforme who was sent for evaluation of recurrence . apart from recurrence at the primary site a subependymal deposit was noted in the trigone of the lateral ventricle which was well demonstrated on t...	a 10-year - boy post - operative , post - radiotherapy case of left temporal glioblastoma multiforme ( gbm ) was referred for f-18 flurodeoxyglucose ( fdg ) positron emission tomography / computed tomography ( pet / ct ) to rule out residual / recurrent disease 6 months following completion of therapy . the fdg scan ...
the mind is never passive ; it is a perpetual activity , delicate , receptive , responsive to stimulus . you can not postpone its life until you have sharpened it . whatever interest attaches to your subject - matter must be evoked here and now ; whatever powers you are strengthening in the pupil , must be exercised he...	curricula for residents on rotations through intensive care units are necessarily abbreviated . the selection ( and omission ) of topics can be informed by assessment of perceived needs . a curriculum can not , however , be formed exclusively from the top - scoring needs . topics that are encountered exclusively ...
monilethrix is an autosomal dominant disorder of hair shaft with regular thinning of hair shaft with fracture of the hair shaft at constricted points , which is commonly caused due to human hair keratin hhb6 gene located on long arm of chromosome 12 . patients have short and fragile hair not requiring haircut since chi...	congenital hypotrichosis may be due to a number of causes and may have multiple systemic associations . a child born of second - degree consanguineous marriage was found to have monilethrix as the cause of congenital hypotrichosis . a detailed systemic evaluation in the child revealed atrial septal defect and a hyp...
2005 after a detailed polyphasic study and reclassification on the genus thermoactinomyces . at present the genus laceyella has four recognized species namely ; laceyella putida , l. sacchari , type species of the genus laceyella , laceyella sediminis and laceyella tengchongensis . cells are aerobic , non - ...	we report the 3.3-mb draft genome of laceyella sacchari strain gs 1 - 1 , isolated from hot spring water sample , chumathang , leh , india . draft genome of strain gs 1 - 1 consists of 3 , 324 , 316 bp with a g + c content of 48.8% and 3429 predicted protein coding genes and 75 rnas . geobacillus thermodenitrifica...
the author receives funding from the swedish research council , the ragnar sderbergs stiftelse , the novonordisk foundation and lund university . the author is also part of the following strategic research consortia in diabetes : the linnaeus lund university diabetes center ( ludc ) funded by the swedish research counc...	common genetic variations in the gene encoding transcription factor 7-like 2 ( tcf7l2 ) reveal the strongest association with type 2-diabetes known to date . these lead to impaired insulin production and output , but the mechanisms of disease remain incompletely known . in this issue of diabetologia , two publicati...

Subsets and Splits

No community queries yet

The top public SQL queries from the community will appear here once available.