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The length of distal convoluted tubule is
Although the DCT is the shoest segment of the nephron, spanning only about 5 mm in length in humans (1), it plays a critical role in a variety of homeostatic processes, including sodium chloride reabsorption, potassium secretion, and calcium and magnesium handling Ref: guyton and hall textbook of medical physiology 12 ...
152,900
medmcqa_train
Which of the following is the extended criteria donor for transplant of kidney?
Ans. (d) All the aboveRef: Bailey and Love 27th edition, Page 1544In kidney transplant extended donor criteria is defined in USA as* Donor age > 60 years (or)* Donor age 50-60 years with any two of the following problems# Hypertension# Death from stroke# Terminal creatinine >132mmol/l.These marginal donors have less sa...
152,901
medmcqa_train
True about meningioms -
Ans. is 'c' i.e., 95% cure rate following treatment Meningiomas o Meningiomas are tumors that arise from the dura mater and are composed of neoplastic (arachnoid cap ) cells. o They are now the most common primary brain tumor, accounting for approximately 32% of the total. (this information has been added in 18th/e of ...
152,902
medmcqa_train
Follow-up ofcataract operations in national blindness control program is done by -
Ans. is 'c' i.e., Sentinel surveillance o 25 sentinel surveillance units have been established in depaments of ophthalmology and PSM in medical collages in India for assessment of - Beneficiary profiles. Visual outcomes based on cataract surgery records. Follow-up of operated cases. Ocular morbity data.
152,903
medmcqa_train
Genital was in pregnancy treatment is
Cryotherapy T/T of anogenital was Topical medication Trichloracetic acid or Podophyllin resin applied weekly. hniquinod or podofilox should also be used. Crvotherapy and laser therapy Cryotherapy (freezing) using nitrous oxide or carbon dioxide is used in was who do not respond to topical treatment. Carbon dioxide lase...
152,904
medmcqa_train
Which of the following will take place during skeletal muscle contraction?
During contraction, the I band decreases in size as thin filaments penetrate the A band. The H band--the pa of the A band with only thick filaments--diminishes in width as the thin filaments completely overlap the thick filaments. A net result is that each sarcomere, and consequently the whole cell (fiber), is greatly ...
152,905
medmcqa_train
Nikolsky's sign is seen in ?
Ans. is `d' i.e., All of the above Niko!sky's sign is seen in ? Pemphigus Toxic epidermal necrolysis Bullous impetigo Steven jonson syndrome Staphylococcus scalded skin syndrome HSV & VZV infection Epidermolysis bullosa Malignancy (leukemia) Mycosis fungoides Bullous lichen planus
152,906
medmcqa_train
A patients hears better in noisy surrounding known as
A. i.e. (Paracusis) (87- Dhingra 4th) (120 - Maqbool 11th)* Paracusis willisii - an otosclerotic (otospongiosis patients hears better in noisy than quite surroundings* In cochlear lesions patients do not hear at conversational intensity but get irritated by loud sound - RECRUITMENT* Sociacusis - is the hearing impairme...
152,907
medmcqa_train
Post exposure prophylaxis is applicable in all except:
Ans. B. Japanese encephalitisHIV - Tenofovir + Lamivudine + Efavirenz; Varicella zoster - Acyclovir or Oka vaccine; Swine influenza - Oseltamivir or quadrivalent vaccine.
152,908
medmcqa_train
Oxidation in pentose phosphate pathway utilises:
The enzymes of the pentose phosphate pathway act in the sequence of reactions of the pathway may be divided into two phases: an oxidative nonreversible phase and a nonoxidative reversible phase. Ref: Harper 28th edition, Chapter 21.
152,909
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Most common testicular tumor in Pre pubertal age
Yolk sac tumors are most commonly found in pre pubertal age group.
152,910
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Malignant melanoma of the choroid will produce: September 2012
Ans. B i.e. Exudative retinal detachment
152,911
medmcqa_train
True about hydatid cyst are all, except ?
Ans. is 'b' i.e., Calcification is common in lung Hydatid disease Liver cysts The majority of hydatid cysts occur in the liver, causing symptoms : Chronic abdominal discomfo Palpable abdominal mass Allergic reactions due to cyst rupture - skin rash, anaphylactic shock, or death. Abscess formation due to secondry bacter...
152,912
medmcqa_train
Renal transplantation is most commonly done in ?
Answer is 'a' i.e. Chr. Glomerulonephritis Renal transplantation is the preferred treatment for many patients with end stage renal disease (ESRD), because it provides a better quality of life for them than dialysis. The most common causes of ESRD (in decreasing order) are: - Diabetes mellitus - Hypeension - Glomerulone...
152,913
medmcqa_train
All are true about measles except-
<p>MEASLES:- An acute highly infectious disease of childhood caused by a specific virus of group myxovirus. Clinically characterised by fever and catarrhal symptoms of the upper respiratory tract( coryza,cough), followed by a typical rash. Incubation period-10 days from exposure to onset of fever and 14 days of appeara...
152,914
medmcqa_train
Posterior cerebral artery supplies all except
Posterior cerebral artery (PCA) supplies blood to occipital lobe (i.e. visual or striate cortex), temporal lobe, thalamus, lentiform nucleus, pineal & medial geniculate body, choroids plexus of inferior horn of lateral ventricle & 3rd ventrical and mid brain.
152,915
medmcqa_train
Minimum recommended level of Residual chlorine in Swimming pools is:
- Level of residual chlorine to be maintained for swimming pool sanitation is > 1.0 mg/L with contact period of 1 hour. - Also Remember, Free/ residual chlorine levels recommended in:- Drinking water = >= 0.5 mg/ L ; with contact period of 1 hour. Drinking water to kill cyclops = >= 2.0 mg/L ; with contact period of 1 ...
152,916
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Cryoprecipitate contains: March 2009
Ans. C: Factor VIII Cryoprecipitate is prepared from plasma and contains fibrinogen, von Willebrand factor, factor VIII, factor XIII and fibronectin. Cryoprecipitate is the only adequate fibrinogen concentrate available for intravenous use. Cryoprecipitate is indicated for bleeding or immediately prior to an invasive p...
152,917
medmcqa_train
All are the Indications of a malignancy in a mammography except
Mammographic features suggestive of breast cancer A solid mass with or without stellate features Asymmetric thickening of breast Clustered microcalcification Presence of fine stippled calcium in and around a suspicious lesion is suggestive of breast cancer and occurs in as many as 50 % of nonpalpable cancers These micr...
152,918
medmcqa_train
A patient wanting to scratch for itching in his amputated limb is an example of:
-This is an example of phantom limb hallucination in which patient is getting sensations from a limb which has been amputated. - In reflex hallucinations, stimulus in one modality causes hallucinations in another modality. E.g- A patient repoed that when he heard the sound of water falling from the tap, he would also s...
152,919
medmcqa_train
The deliusion which involves replacement of a familiar person by someone else is ?
Ans. is 'a' i.e., Capgras syndrome DSM is characterized by misidentification delusions of other or self. Four main syndromes are differentiated : ? Capgras syndrome (Delusion of double) : - Patient falsely sees a familiar person as a complete stranger who is impoing on him as a familiar person. Fregoli syndrome (illusi...
152,920
medmcqa_train
Hysteroscope procedure is done for -
Ans. is 'd' i.e., Uteruso Hysteroscopy is a procedure that allows your doctor to look inside your uterus in order to diagnose and treat causes of abnormal bleeding. Hysteroscope in the scope used for visualization of the uterus.
152,921
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A child has microcephaly, Blue eyes, Fair skin, and Mental retardation, Ferric chloride test is positive. What is the likely diagnosis
Individuals with phenylketonuria have profound and irreversible intellectual disability,microcepgaly,epilepsy and behavioral problems.These patients often have a musty body odour and skin conditions such as eczema caused by excretion of excessive phenylalanine and its metabolites.Decreased skin hair, and eye pigmentati...
152,922
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Maximum congestion is seen in :
C i.e. Strangulation
152,923
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The drug which causes renal papillary necrosis is?
Ans. (a) AcetophenetidinRef: Robbiris pathology 9th ed. /423. 936t* Renal papillary necrosis due to acetophenetidin/ phenacetin is a gradual process with slow loss of renal function.* The most common cause of renal papillary necrosis is diabetic glomerulopathy
152,924
medmcqa_train
"Genital elephantiasis" is caused by
(Lymphogranuloma venereum) (428-A7th)LYMPHOGRANULOMA - VENEREUM (Lymphogranuloma inguinale, poradenitis, climatic or tropical bubo)- Caused by chlamydia -trachomatis - L2 (Most commonly)- Preferred site - regional lymphnodes- Primary lesions - painless papulovesicular lesion ** on the external genitalia- Women - hemorr...
152,925
medmcqa_train
Which of the following drug does not cause renal toxicity-
Ans. is 'c' i.e., Mycophenolate Mofetil o Nephrotoxicity is not an adverse effect of mycophenolate mofetil.
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Coical representation of body in cerebrum is
B i.e. Veical
152,927
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Which of the following type of renal tubular acidosis (A) is associated with hyperkalemia?
-Type IV A(hyporeninemic hypoaldosteronism) is the most common A- It may occur in type 1 or 2 DM- Associated with moderate renal dysfunction and characterised by hyperkalemiaRef: Harrison's 18/e p2364
152,928
medmcqa_train
The treatment of choice for Anaplastic carcinoma of thyroid infiltrating trachea and sternum will be
Anaplastic carcinoma of thyroid with distant metastasis or invasion into locally unresectable structures, such as the trachea or vasculatureof the anterior mediastinum, leads to a more conservative surgical approach, such as tracheostomy (palliation) as prognosis is very poor Postoperative external beam irradiation or ...
152,929
medmcqa_train
Lymphocytic colitis -
Lymphocytic colitis Lymphocytic colitis is characterised by chronic watery, non-bloody diarrhoea and a prominent intraepithelial infiltrate of lymphocytes. Lymphocytic colitis affects male and female equally. Pt. presented with 3-20 times non-inflammatory non-bloody watery diarrhoea and accompanied by cramping abdomin...
152,930
medmcqa_train
Cytochrome C in apoptosis acts by
After releasing of cytochrome in cytosol, they binas to Apart 1 protein which leads to formation of a complex apoptosome. This complex binds to caspase-9 which is a critical initiator caspase of the mitochondrial pathway of apoptosis. Also Know Most critical organ for apoptosis = Mitochondrion Most characteristic featu...
152,931
medmcqa_train
True about a negatively skewed data
A left skewed distribution or negatively skewed distribution because it's long tail is in the negative direction on a number line. The mean is to the left of the peak.(mode) The tail is longer on the left. In most cases, the mean is to the left of the median. mean < median < mode
152,932
medmcqa_train
Sweating as a result of excretion is mediated through
Refer kDT 7/e p 93 Most aeries and veins in the body are innervated by sympathetic adrenergic nerves, which release norepinephrine (NE) as a neurotransmitter. Some blood vessels are innervated by parasympathetic cholinergic orsympathetic cholinergic nerves, both of which release acetylcholine (ACh) as their primary neu...
152,933
medmcqa_train
A 40-year-old woman had lower third molar extracted due to dental caries. Then she developed high fever and pain. On examination, tonsil deted medially and there was swelling in upper one-third of sternocleidomastoid muscle, Most likely diagnosis is:
Abscess of pharyngomaxillary or lateral pharyngeal space is also known as parapharyngeal abscess. Infection can come to this space from acute or chronic infections of tonsils and adenoids, bursting of peritonsillar abscess, dental infection of lower third molar teeth, Bezold's abscess, petrositis, infections of parotid...
152,934
medmcqa_train
'Favus' is caused by?
Favus Favus is an inflammatory type of Tinea capitis Commonest causative agent T. schoenleinii. Inflammatory (kerion, us) causing scarring/cicatricial alopecia Kerion common in children Tender boggy swelling over scalp, easily pluckable hair and enlarged lymphnode.(causative agent: T. mentagrophyte or T. verrucosum) DO...
152,935
medmcqa_train
True statement about the upper half of anal canal is -
Upper part of anal canal above pectinate line is supplied by autonomic nerves and is therefore insensitive to pain. Upper part of anal canal above pectinate line is drained by inferior mesenteric node (into internal iliac nodes), lined by columnar epithelium and is supplied by superior rectal artery (Continuation of in...
152,936
medmcqa_train
Among the following true about linezolid except
OXAZOLIDINONE Linezolid:- Mech of action:- Linezolid inhibits bacterial protein synthesis by acting at an early step and a site different from that of other AMAs. It binds to the 23S fraction (P site) of the 50S ribosome and interferes with formation of the ternary N-formylmethionine- tRNA (tRNAfMet) -70S initiation co...
152,937
medmcqa_train
Which suture is absorbed in 180 days
Answer- A. PolydiaxononePolydioxanone suture provides wound suppo for longer period as compared to other synthetic absorbable sutures.Polydioxanone suture also offers far superior tensile strength. Polydioxanone suture is made from polymerizing para dioxanone monomer.
152,938
medmcqa_train
Which of the following is a reference to Millards rule?
The timing of the lip repair in infancy varies from first 48 hours of life to 6 months of age, depending on the surgeon’s judgement. Although there is always a debate as to when the surgery should be performed, most surgeons follow ‘Millard’s rule of 10.’ 10 weeks of age with 10 gm of Hb and 10 pounds of weight. The tr...
152,939
medmcqa_train
A 32-year-old woman seeking to become pregnant visits her physician for a pre-pregnancy examination. Routine prenatal laboratory testing demonstrates the following profile: HBsAg (-), anti-HBsAg (+), anti-HBcAg (-), anti-HBeAg (-), and HBV DNA (-). Which of the following likely represents the status of the patient?
The patient is only positive for antibody to the hepatitis B antigen. This suggests that the patient has been vaccinated for hepatitis B virus (HBV). The vaccine consists of recombinantly produced HBV surface antigen (HBsAg) alone; Antibodies to the core protein (anti-HBcAg) appear during acute illness and between the ...
152,940
medmcqa_train
Which is a GABA transaminase inhibitor ?
Ans. is 'c' i.e., Valproate Mechanism of action Facilitation of GABA mediated C1 channel opening Barbiturates and benzodiazepines bind to GABAAreceptor and open Cl- channel. Valprote and vigabatrine inhibit enzyme GABA transaminase which degrades GABA r conc. of GABA. Tiagabine inhibits the uptake of GABA into the neur...
152,941
medmcqa_train
True about fetal circulation –
Blood in IVC has more saturation than blood in SVC as IVC carries the oxygenated blood of umbilical vein. The left ventricular blood has more oxygen saturation that right ventricular blood because it carries the blood of IVC, while blood in right ventricle is a mixture of blood from IVC and SVC. So, the brain and coron...
152,942
medmcqa_train
Hypnogogic hallucination is -
Ans. is 'a' i.e., If experienced while falling asleep o Hallucinations which occur just prior to falling asleep are called hypnagogic hallucinationso Hallucination which occur just prior to waking up are called hypnopompic hallucinations.Also remember1) Functional hallucinations:- Hallucination accompanies a provoking ...
152,943
medmcqa_train
Which of the following is false about plunging ranula
Diagnosis is made by USG or MRI.
152,944
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A child is brought to the paediatric OPD with fever of 24 hours duration. History reveals 3 episodes of chest infection and passage of foul smelling stools. The most probable diagnosis is –
Recurrent chest infection in a child with evidence of exocrine pancreatic insufficiency (bulky, foul smelling stool) suggest a diagnosis of cystic fibrosis.
152,945
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Metyrosin is used in ?
Ans: D PheochromocytomaRef: KDT 7/e p. 128, 129; Katzung rlth/e p. g4lRate limiting step (tyrosine hydrorylation) in synthesis of epinephrine is inhibited by metyrosine.
152,946
medmcqa_train
In congenital adrenal hyperplasia, deficient enzyme is - most womon
Ans. is 'b' i.e., 21-a Hydroxylase Congenital adrenal hyperplasia (CAH) Group of AR disorder MC adrenal disorder in childhood Most common 21-hydroxylase deficiency In 21a-hyroxylese deficiency There is deficiency of mineralocoicoids & glucocoicoid. This leads to hypoglycemia, hyponatremia
152,947
medmcqa_train
Calculate the mean & mode of the given values: 2,2,3,4,4,4,4,5,5,7,8,8,9
Ans. (b) 5 and 4Ref: Park 22nd ed/789-90Therefore, mean =2+2+3+4+4+4+4+5+5+7+8+8+913= 65/13Mean = 5* Mode is most repeated/frequent value, which is 4, repeated 4 times.* Therefore the mean, mode will be 5 and 4 respectively.
152,948
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A child with large perimembranous VSD has congestive hea failure. What may be the cause of improvement of failure in this patient
Patients born With uncomplicated VSD may develop pulmonary stenosis due to hyperophy of right ventricular infundibulum ,develop pulmonary aerial hypeension or rarely develop aoic regurgitation. Development of pulmonary aerial hypeension is dreaded complication since if it is of obstructive type the patient becomes inop...
152,949
medmcqa_train
Triiodothyronine (T3) as compared to T4 :
T3 is the main active thyroid hormone. It is more potent (less plasma protein bound) and faster acting than T4. How­ever, short duration of action limits its use for the treatment of hypothyroidism (requires lifelong treatment). T3 is indicated for the treatment of myxedema coma.
152,950
medmcqa_train
In an average young adult male, water constitutes about ______ % of the body weight.
Body is composed of about 60-70% water. Osmolality of the intra and extracellular fluid is the same, but there is a marked difference in the solute content.
152,951
medmcqa_train
Which by product of vecuronium is associated with peripheral neuropathy on prolonged infusion-
The most potent byproduct of vecuronium is 3-hydroxy vecuronium, with approximately 60% of the activity of vecuronium, is excreted by the kidney and may be responsible for prolonged paralysis. Vecuronium - 1. It is unstable in solution and, for this reason, is supplied as a lyophilized powder that must be dissolved in ...
152,952
medmcqa_train
A 10-month old male child was having vomiting upon eating fruits, but is of normal weight. He has been exclusively breast fed till now. The doctor suggests fructose intolerance. Which of the following enzyme would be deficient in this child?
Ans. a. Aldolase B
152,953
medmcqa_train
The investigation of choice to detect gastrinoma le<< than 5 mm size is-
Investigations Upper gastrointestinal endoscopy is the investigation of choice and should be performed promptly in any dyspeptic patient with 'alarm features' . Multiple biopsies from the edge and base of a gastric ulcer are required. Barium meal is a poor alternative, since any abnormalities must be followed by endosc...
152,954
medmcqa_train
Infra clavicular lesion of tuberculosis is known as ?
Ans. is 'a' i.e., Assman's focus Assman's focus The initial lesion in secondary tuberculosis at the apex of lung (infraclavicular) without any lymph node involvement is called Assman's focus.
152,955
medmcqa_train
Regarding appendicitis in children, all are true except:
Ref: Nelson's Textbook of Pediatrics, 19th edition. Robbins Pathologic Basis of Disease, 8th edition & Bailey and Love's Short Practice of Surgery 25th Edition Explanation: localized abdominal tenderness is the single most i: hie finding in the diagnosis of acute appendicitis. In Children, if the diagnosis is delayed b...
152,956
medmcqa_train
Melanosis coli is caused by
Senna and cascara are anthraquinone derivatives, which are used as stimulant purgatives. On chronic use they can lead to melanosis coli.
152,957
medmcqa_train
Lateral rectus palsy is characterized by -
First see the difference between phoria and tropia. Suffix phoria is used in latent squint, e.g. esophoria and exophoria. Suffix tropia is used in manifest squints (concomitant and paralytic) e.g. esotropia or exotropia. Diplopia is a feature of paralytic esotropia or exotropia but not concomitant esotropia / exotropia...
152,958
medmcqa_train
Cystic fibrosis is inherited as?
Ans. is 'a' i.e. AR * Cystic fibrosis is an autosomal recessive disorder of ion transport in epithelial cells that affect fluid secretion in exocrine glands and the epithelial lining of the respiratory, gastrointestinal and reproductive tracts.* Cystic fibrosis occurs due to mutation in the CFTR (Cystic fibrosis transm...
152,959
medmcqa_train
Bronchopulmonary segments in right and left lungs respectively ?
Each lung has 10 bronchopulmonary segments.
152,960
medmcqa_train
Wide open anterior fontanelle is found in following diseases except:
d. Craniosynostosis(Ref: Nelson's 20/e p 2817-2819, Ghai 8/e p 41)In Craniosynostosis there is premature fusion of cranial sutures and so fontanelles close early and are small;While, Rickets, Cretinism (Hypothyroidism), Ostoeogenesis imperfecta & Achondroplasia are important causes of large anterior fontanelle.
152,961
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Mallampatti's classification is for?
Ans. is 'd' i.e., Inspection of oral cavity before intubation Mallampati score (Mallampati oropharyngeal scale)* Mallampati grading is used to evaluate the visibility of tonsil and tonsillar fossa which in turn assess the adequate mouth opening depending upon the grade.* Indications of Mallampati score are Oral cavity ...
152,962
medmcqa_train
Triphasic waveforms in hepatic encephalopathy occurs in stage of -
Hepatic encephalopathy Hepatic encephalopathy is a neuropsychiatric syndrome caused by liver disease. As it progresses, delirium is followed by coma. Simple delirium needs to be differentiated from delirium tremens and Wernicke's encephalopathy, and coma from subdural haematoma, which can occur in alcoholics after a fa...
152,963
medmcqa_train
Energy selection in CPR according to AHA 2010 guideline is/are:
Answer- (D) Monophasic 360 J, Biphasic 120-200 J2010 AIIA guideline for CPR Contrary to previous recommendation of 3 succesive shocks (200, 300, 360J) nowadays lst & all subsequent shocks are of 360 Joules with monophasic & 120-200 loules with biphasic.
152,964
medmcqa_train
Maximum liver toxicity is seen with which anti - TB drug?
Ans. is 'c' i.e., Pyrazinamide o Three first line antitubercular drugs are associated with hepatotoxicityRifampicinFNHPyrazinamideo Of the three, rifampicin is least likely to cause hepatocellular damage, although it is associated with cholestatic jaundice.o Pyrazinamide is the most hepatotoxic of the first line drugs....
152,965
medmcqa_train
Sacrococcgeal teratoma arises from ?
The cause of sacrococcygeal teratomas is unknown. Sacrococcygeal teratomas are germ cell tumors. Germ cells are the cells that develop into the embryo and later on become the cells that make up the reproductive system of men and women. Most germ cell tumors occur in the testes or ovaries (gonads) or the lower back. Whe...
152,966
medmcqa_train
Leprosy commonly affects all organs except:
Ovary
152,967
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The substance used of OCG is:
Ans. lapanoic acid
152,968
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Most common gene associated with renal cell carcinoma
Both sporadic and familial RCC is associated with: Loss of sequence on chromosome 3 either by translocation (3:6, 3:8, 3:11) or deletion. This region harbours the VHL gene. Familial RCC is associated with:- Von Hippel-Lindau syndrome Ref: RAM DAS NAYAK EXAM PREPARATORY MANUAL FOR UNDERGRADUATES 2nd ed. pg no: 633
152,969
medmcqa_train
Myasthenia gravis may be associated with:
Ans: dRef: Harrison, 16thed, p. 2521, Table 366.3
152,970
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Which of the following act to cause local Vasodilators
(| CO2 tension) (500-1-K.S) (597-GN) (563-Ganong 23rd)Local vasodilatorsVasodilators of metabolic originVasodilators of endothelial origin* The vasodilators of metabolic origin are carbon dioxide, lactate, hydrogen ions and adenosine, Histamine* The metabolic changes that produce vasodilation include in most tissues de...
152,971
medmcqa_train
Drug of choice for pneumocystis carinii is:
Answer is B (Cotrimoxazole): Trimethoprim/sulfamethoxazole or Cotrimoxazole is the drug of choice for all firms of Pneumocystis Pneumonias. 'Trimethoprim-Sulfamethoxazole which acts by inhibiting folic acid synthesis is considered the drug of choice for all forms of Pneumocystis Pneumonias. Therapy is continued for 14 ...
152,972
medmcqa_train
Absent P waves with wide QRS complex indicates serum potassium of
Hyperkalemia Couesy of Dr. Michael McCrea a. Tall hyperacute T wave (earliest ECG finding) b. Prolonged PR interval c. Flattened or absent P wave d. Wide QRS complex that eventually blends with the T wave to assume a "sine wave" appearance e. Hea blocks f. QT interval normal or shoened Ref: guyton and hall textbook of ...
152,973
medmcqa_train
If mother is donating the kidney to her son, this is an example of:-
Types of grafts - Autograft: same person - Allograft/Homograft: from one person to another / same species - Isograft: Identical twine - Xenograft/Heterograft: Between different species - Ohotopic graft: Graft placed in normal anatomical site - Heterotrophic graft: Graft in site different from its anatomical location
152,974
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Which of following drug inhibits xanthine oxidase: September 2007
Ans. C: Allopurinol Xanthine oxidase is involved in purine metabolism. Inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. Xanthine oxidase inhibitors are: a....
152,975
medmcqa_train
Features in retinal detachment all except –
Vitreous hemorrhage is not a feature of retinal detachment. However, it may be associated with retinal detachment as tear in retina may cause vitreous hemorrhage or retinal detachment. In retinal detachment, there is visual field defect which corresponds to the area of detachment. On examination, freshly - detached  re...
152,976
medmcqa_train
True about silent mutation in genea) No change in mRNAb) No change in Amino acid sequence in proteinc) No expression of proteind) No change in expression of proteine) Termination of protein synthesis
In silent mutation, codon containing the changed base codes for the same amino acid (as original codon). Thus there is no change in expression of protein.
152,977
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Advantages of amoxicillin over ampicillin are all except?
Ans. is 'b' i.e., Spectrum includes H. influenzae & Shigella
152,978
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Which of the rotator muscle was not given its due impoance and was called Forgotten muscle of rotator cuff ?
Subscapularis-:"forgotten muscle'' of rotator cuff- Internal rotator of the shoulder Difficult to pick up in MRI Diagnostic test done-lift off, belly press, Gerber test Nerve supply: Upper and lower subscapular nerves from posterior chord of brachial plexus
152,979
medmcqa_train
Which of the following disorders is most closely associated with thyroid disease?
Ans. C. DepressionDepressive symptoms have been known to be one of the most prominent features of clinical thyroid disease, particularly hypothyroidism. Beginning in the late part of the 19th century, depression was seen as prominent component of clinical hypothyroidism, although other psychiatric symptoms were often p...
152,980
medmcqa_train
Mallory hyaline bodies are present in all of the following, except
In histopathology, a Mallory body,Mallory-Denk body, and Mallory's hyaline, is an inclusion found in the cytoplasm of liver cells. Mallory bodies are damaged intermediate filaments within the hepatocytes
152,981
medmcqa_train
Definitive managenment in primary angle closure glaucoma: March 2005
Ans. C: Laser iridotomy Although intraocular pressure is only one of the major risk factors for glaucoma, lowering it various pharmaceuticals and/or surgical techniques is currently the mainstay of glaucoma treatment. A. Medications used for lowering intraocular tension: Prostaglandin analogs like latanoprost, bimatopr...
152,982
medmcqa_train
A 64-year-old man undergoes CEA surveillance for cancer, because his brother and father both had colon cancer. What information should he be provided?
CEA is useful in the follow-up care of patients with colon carcinoma after resection. The levels of this antigen usually come to normal after complete resection of the tumor. A subsequent elevation may suggest a recurrence of the tumor either at the resection margin or at distant sites. The sensitivity and specificity ...
152,983
medmcqa_train
All are true about spermatocytic seminoma except:
Ans: a (3 types are there) Ref: Robbins, 7th ed, p. 1042Spermatocytic seminoma is a non seminomatous slow growing testicular tumour seen in old age. It does not have three types.Spermatocytic seminoma* Both clinically & histologically distinct from seminoma* Variant of germ cell tumour that do not arise from an intratu...
152,984
medmcqa_train
Schedule of drug to be sold only on prescription is:
Ans. A. HCAScheduleContent1ASpecimens of forms2BFees of tests/analysis3CBiological special products4DExtent and conditions of exemptions regarding import5EList of poisonous medicine under Ayurveda6FRequirement for functioning of blood bank7GDangerous to take these drugs except under medical supervision8HPrescription dr...
152,985
medmcqa_train
Internal podalic version is done in
Internal podalic version is done for only delivery of second twin (Transverse lie).
152,986
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The complete genome sequence of M. tuberculosis comprises of which of the following?
The complete genome sequence of M. tuberculosis comprises 4043 genes encoding 3993 proteins and 50 genes encoding RNAs and its high guanine-plus-cytosine content (65.6%) is indicative of an aerobic lifestyle. Reference : Harrisons Principles of Internal Medicine, 18th Edition, Page 1340
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Most common type of primary lymphedema is?
ANSWER: (B) Lymphedema precoxREF: Sabiston 18'h edition chapter 69, style="color: rgba(0, 0, 0, 1); font-family: Times New Roman, Times, serif"> primary_lymphedema.htm' The most common form of primary lymphedema is praecox, which accounts for about 80% of the patients. Congenital and tarda lymphedemas each account for ...
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Which of the following is not an enzyme inhibitor
Griseofulvin and chronic alcohol intoxication are enzyme inducers.
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PKU is a congenital amino acid metabolic disorder. In the following rare variants of PKU, dihydrobiopterin synthesis is affected. The enzyme deficient is
In Type 2 and 3 of PKU, there is deficiency of enzyme dihydrobiopterin reductase. Hence there is deficiency of dihydrobiopterin.Ref: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 236
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Transovarian transmission is a feature of-
The causative agent of scrub typhus: Rickettsia tsutsugamushi. It is the larva that feeds on veebrate hosts and picks up the rickettsias. The larval stage serves as both as a reservoir, through ovarian transmission and as a vector for infecting humans and rodents (refer pgno 300 park 23rd edition)
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Defect in Menke disease:
MENKE DISEASE / kinky OR STEEL HAIR SYNDROME- deficiency of copper results in defective crosslinking of collagen and elastin by the copper-dependent enzyme lysyl oxidase. Defect in dietary absorption of copper Die with in 5 years of age Kinky hair and growth retardation. menke disease is X linked disease due to mutatio...
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A 70-year-old gentleman met with an accident, he was able to point to pain site and opens eyes when pinched, he is confused and not sure where he is now or how he met with an accident. What will be his minimum GCS
His GCS would be 11Glasgow Coma ScaleEyes open Spontaneously 4To verbal command 3To painful stimulus 2Do not open 1Verbal Normal oriented conversation 5Confused 4Inappropriate/words only 3Sounds only 2No sounds 1Intubated patient TMotor Obeys commands 6Localises to pain 5Withdrawal/flexion 4Abnormal flexion 3Extension ...
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Induction agent, having anti-emetic property is:
Propotol is used as induction agent, it cause decrease in blood pressure heart rate and vascular resistance. Nausea and vomiting is very rare (1 -2%), and less than with most other used agents.
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Insulin mediated glucose transpo is seen in ?
Ans. is 'a' i.e., Adipose tissueInsulin stimulates the uptake of glucose by myocytes (skeletal muscle, cardiac muscles), adipocytes (adipose tissue) and hepatocytes. Tissues that do not depend on insulin for glucose uptake include brain, erythrocytes (RBC), the epithelial cells of kidney & intestine, Liver, and Cornea ...
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What are the chances of veical transmission of Hepatitis B in women who are seropositive for both HBsAg and HBeAg ?
Ans:D.)90% Veical Transmission of Hepatitis B In patients with acute hepatitis B veical transmission occurs in up to 10% of neonates when infection occurs in the first trimester and in 80 -90% of neonates when acute infection occurs in the third trimester. In women who are seropositive for both HBsAg and HBeAg veical t...
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Which disease is transmitted by all the components of blood -
The malariaparasites enter that person's bloodstream and travel to the liver. When the parasites mature, they leave the liver and infect red blood cells.
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Largest reserve of energy in body stored as
Fat (triglycerides) in the adipose tissues is the largest store of energy of the body.
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Disease associated with excessive maize diet -
Ans. is 'b' i.e., Pellagra o Excess of Leucine interferes in conversion of Tryptophan into Niacin, and aggravates the pallagrogenic action of maize.o Similar to maize, Jowar also contains excess of leucine.o Leucine interferes with conversion of tryptophan to niacin.o Pellagra has been reported in India in Telangana ar...
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