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A patient presented with a 3.5-cm size lymph node enlargement, which was hard and present in the submandibular region. Examination of the head and neck did not yield any lesion. Which of the following investigations should follow?
Suspected lymph node may have metastases from the upper aerodigestive tract. Since no lesion is found on physical examination of head and neck, triple endoscopy would be justified next. Supravital staining helps in selecting the site of biopsy in a lesion. As no lesion is discovered, it will not be very useful.
3,900
medmcqa_train
Hour glass deformity is seen in -
Hour glass stomach is caused due to cicatracia contraction of a saddle shaped ulcer at the lesser curvature.
3,901
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Most common detion used in social medicine is-
Ans. is 'd' i.e., Standard detion "Standard detion is most common and generally most appropriate measure of dispersion (variation)".
3,902
medmcqa_train
Which of the following is an investigation of choice to diagnose gall stones?
Ans. B. Ultrasound abdomenCholelithiasis involves the presence of gallstones which are concretions that form in the biliary tract, usually in the gallbladder. Choledocholithiasis refers to the presence of one or more gallstones in the common bile duct (CBD) Patients with uncomplicated cholelithiasis or simple biliary c...
3,903
medmcqa_train
The Most common complication in varicose vein surgery is
(A) Ecchymosis # Complications of varicose vein surgery: Bruising and discomfort are common following removal of varices, especially where the veins were of very large diameter. However, the pain usually requires only mild analgesics.
3,904
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Females with orgasmic difficulties are advised following exercises to strengthen pubococcygealmuscles-
Ans. is 'a' i.e., Kegel's exercises o Kegels exercises are used to strengthen the pelvic floor muscles mainly pubococcygeal.o These exercises can thus be used to treat orgasmic difficulties and prevent genital prolapse.
3,905
medmcqa_train
A 3 year old male presents with a skin rash and epistaxis. He has had several, severe sinopulmonary infections. A careful history reveals that his maternal uncle died of bleeding complications following an emergency cholecystectomy. What additional findings are likely in this case?
This clinical scenario is typical for Wiskott-Aldrich syndrome. This is a sex-linked recessive disorder presenting with the triad of thrombocytopenia, eczema, and recurrent sinopulmonary infections. Serum IgM levels are low but IgG, IgA, and IgE levels are increased. Patients have a defective response to polysaccharide...
3,906
medmcqa_train
Age for regular mammography is
Screening mammography: For screening purpose it is done after 40 years. Early screening is indicated when there is family history of carcinoma breast or histological risk factor. Mammography before 35 years of age is usually not done unless there is a suspicious lump or a strong family history. Screening is done in asy...
3,907
medmcqa_train
The spine of the scapula can be palpated at which of the following level of veebrae?
Spine of the scapula lies at the level of T3 veebrae. Scapular spine is seen on the posterior surface of the scapula and it expands into a terminal process called acromion process. The scapulae overlie the posterior poion of the thoracic wall, and cover the upper seven ribs. The superior angle of scapula can be palpate...
3,908
medmcqa_train
NAD acts as a cofactor for
In the TCA cycle,Step 3. In the third step, isocitrate is oxidized and releases a molecule of carbon dioxide, leaving behind a five-carbon molecule--a-ketoglutarate. During this step, \text{NAD}^+NAD + N, A, D, sta superscript, plus, end superscript is reduced to form \text{NADH}NADHN, A, D, H. The enzyme catalyzing th...
3,909
medmcqa_train
Criteria for a pancreas donor include:
- Combined liver-pancreas procurement should be routine, even if the right hepatic aery arises from the superior mesenteric aery. - In this situation, since the transplanted liver is the life-saving organ, the proximal superior mesenteric aery should remain with the liver and the distal superior mesenteric aery supplyi...
3,910
medmcqa_train
Indication for intramuscular iron therapy is
Refer KDT 6/e p 868 Drug of choice for acute iron poisoning is desferroxamine, however it has to be admistered parentarally It is not effective by oral route In beta thalassemia major iron excess can result due to repeated blood transfusions and massive Hemolysis Cheating agent has to be admistered for long time OK thi...
3,911
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Beta 2 selective agonist are often effective in
Ref-KDT 6/e p127 Beta 2 agonist are useful in premature uterine contraction to delay labour and not for delayed labour. Beta blockers are used in the treatment of the angina
3,912
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Which of the following refers to the occurrence of hypehyroidism following administration of supplemental iodine to subjects with endemic iodine deficiency goiter?
Jod Basedow Effect: Refers to induction of thyrotoxicosis by iodine in the form of dietary supplements or medication, especially especially in patients who are relatively iodide deficient. Treatment includes combination of antithyroid drugs and perchlorate paicularly in amiodarone-induced thyrotoxicosis. Ref: Harrison'...
3,913
medmcqa_train
Seoli cells play a key role in which of the following process
Seoli cells are elongated cells in the seminiferous tubules that ensheathe spermatogenic cells, providing a microenvironment that suppos spermiogenesis and spermatocytogenesis; they secrete androgen-binding protein and establish the blood-testis barrier by forming tight junctions with adjacent Seoli cells.Ref: Ganong&;...
3,914
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According to WHO, crede's method is applied for prophylactic use in ophthalmia neonatorum, is
(Silver nitrate solution): Ref: 164-65-P, 71-KHOPHTHALMIA - NEONATORUM: any discharge or even watering from the eyes in the first week of life should arouse suspion of ophthalmia neonatorum* Use of either 1% tetracycline ointment or 0.5% erythromycin ointment or 1% silver nitrate solution (Crede's method) into the eyes...
3,915
medmcqa_train
A 6-week pregnant lady is diagnosed with sputum positive TB. Best management is -
Ans. is 'b' i.e., Start Category I ATT in first trimester * Tuberculosis during pregnancy should be diagnosed promptly and as early as possible. Late diagnosis and care is associated with 4-fold increase in obstetric morbidity and 9-fold increase in preterm labor.* Poor nutritional states, hypoproteinemia, anemia and a...
3,916
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Commonest cause of acute intestinal obstruction is:
SMALL BOWEL OBSTRUCTION - Adhesions secondary to previous surgery are the MC cause of SBO. - Causes: Adhesions (60%) > Malignant tumors (20%) >Hernia (10%) > Crohn's disease (5%)Q. - Primary colonic cancers (paicularly those arising from the cecum and ascending colon) may present as a SBO.
3,917
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The criteria for validity of a screening test are -
Ans. is 'b' i.e., Predictability Screening test to be applied o The screening test to be applied should fulfil the following impoant criteria before it is considered suitable for screening : ? 1. Acceptability The test should be acceptable to the people at whom it is aimed. In general painful or embarrasing tests e.g.,...
3,918
medmcqa_train
Aery supplying major pa of superolateral surface of brain is
The middle cerebral aery is the largest terminal branch of the internal carotid aery and it runs laterally in the lateral cerebral sulcus of the brain.It supplies the entire lateral surface of the cerebral hemisphere except the narrow strip along the superomedial border extending from the frontal pole to the parieto-oc...
3,919
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Double apical impulse is seen in?
ANSWER: (A) HOCMREF: Harrison's 17th ed chapter 227"Most HOCM patients demonstrate a double or triple apical precordial impulse and a fourth heart sound. Those with intraventricular pressure gradients may have a rapidly rising arterial pulse. The hallmark of HOCM is a systolic murmur, which is typically harsh, diamond-...
3,920
medmcqa_train
Tocilizumab used against Rheumatoid arthritis is a monoclonal antibody against :
Monoclonal antibody against IL-6 : Tocilizumab                Monoclonal antibody against IL-6 receptor : Sarilumab Both are approved for Rheumatoid arthritis.
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Sequence which is responsible for retaining proteins in membrane
D i.e. Halt signal
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Most important amino-acid substrate for gluconeogenesis -
Ans. is 'd' i.e., Alanine o The major noncarbohydrate precursors (substrate) for gluconeogenesis are lactate, pyruvate, glycerol, glucogenic amino acids, propionate and intermediates of the citric acid cycle. All aminoacids, exceptfor leucine and lysine, are substrate for gluconeogenesis. Alanine is the most important ...
3,923
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Investigation of choice in appendicitis in adults
Answer- A. CT Scan
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A 66 year old female is posted for subtotal gastrectomy for adenocarcinoma. The important procedure related complication:
Ans. (d) Bilious vomitingRef: Sabiston 20th Edition, Page 1212Complications of Gastric Surgeries:* Dumping syndrome* Afferent loop syndrome* Efferent loop syndrome* Malabsorption syndrome (Anemia, hypocalcemia, B12 deficiency)* Alkaline reflux gastritis* Bile reflux gastritis* Gastric atony* Duodenal stump blow out.
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Treatment of TOF ?
Ans. is 'a' i.e., Modified BT shunt
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All of the following are cause of blood in stools in children except -
Ans. is 'b' i.e., Carcinoma
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Seoli cells secrete ?
Ans. is 'd' i.e., InhibinLeydig cells have receptors for LH and secrete androgens, i.e. Testosterone, dihydrotestosterone (DHT), androstenedione, and dehydroepiandrosterone (DHEA).Seoli cells have receptors for FSH and secrete ABP, inhibin and MIS. seoli cells also have receptor for testosterone.
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The term 'psychoanalysis' is associated with: March 2009
Ans. C: Sigmond Freud Psychoanalysis/Freudian psychology is a body of ideas developed by Austrian physician Sigmund Freud and continued by others. It is primarily devoted to the study of human psychological functioning and behavior, although it can also be applied to societies. Psychoanalysis has three applications: A ...
3,929
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All the following can occur in a neonate for heat production except –
"Always remember that newborn cannot produce heat by shivering." Thermogenesis in Newborn A newborn is more prone to develop hypothermia because of a large surface area per unit of body weight. A low birth weight baby has decreased thermal insulation due to reduced subcutaneous and brown fat.
3,930
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Muscle not included in Anterior compartment of thigh
Gracilis is a muscle of Medial compartment
3,931
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Ziemann's dots in RBC are seen in infection with
Ziemann dots in RBC-PL Malaria Schaffner dots in RBC- Pl vivax Accola rings-falciparum Ref: D.R. Arora. Medical parasitology 4th ed pg 108
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Which of the following is not an example of Phase II drug metabolic reaction?
phase 1 reactions- oxidation, reduction, cyclization, decyclization and hydrolysis Phase II reactions: 1. Glucuronidation 2. Acetylation 3. Glutathione conjugation 4. Glycine conjugation 5. Sulfation 6. Methylation 7. Water conjugation Reference: Katzung Pharmacology; 13th edition; Chapter 4; Drug Biotransformation
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Which of the following is not true about tabes Dorsalis -
Ans. is 'b' i.e., Deep tendon reflexes are brisk Tabes dorsaliso Usually develops 15 - 20 years after syphilis infectiono Major symptoms are- lightning pain, ataxia, urinary' incontinenceLightning paino Lightning or lancinating pain are sharp stabbing pain and brief like a flash of lightning.o More common in legs.o Are...
3,934
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'Scalloping' of the edge of sigmoid colon on barium enema seen in:
Ans. Pneumatosis intestinalis
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The cutoff point of serum estrogen level for the diagnosis of ovarian failure:
Diagnosis of menopause is from classical symptom of hot flush (50%) confirmed by elevated FSH levels to more than 100 mlU/ml and serum estradiol < 20 pg/ml.
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Post term pregnancy is the pregnancy which continues beyond: September 2006
Ans. C: 294 days The normal duration of pregnancy is approximately 37 to 42 weeks, with the estimated due date at 40 weeks or 280 days from the first day of the last menstrual period. A postterm pregnancy/prolonged pregnancy/post maturity is one that has extended beyond 2 weeks of the expected date of delivery (beyond ...
3,937
medmcqa_train
A 45-year-old man is admitted to the hospital with breathing problems. During physical examination the patient shows signs of airway obstruction. A CT scan examination reveals a nasal polyp obstructing the airway. Drainage from which of the following structures is also obstructed?
(b) Source: GAS 797, 879, 1018, 1020, 1022; GA 487, 518, 525 The nasal polyp also involved the maxillary sinus, located immediately laterally to the nasal cavity. The sphenoid sinus, located posterosuperiorly to the nasopharynx, is unlikely to be affected by a nasal polyp. The ethmoidal sinuses, located medially to the...
3,938
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Gene associated with autosomal dominant breast cancer?
Ans. B. BRCA 1. (Ref. Bailey and Love 26th/pg. 817)The BRCA1 gene has been associated with an increased incidence of breast (and ovarian) cancer and is located on the long arm of chromosome 17 (17q). The gene frequency in the population is approximately 0.0006. It does, however, occur with greater frequency in certain ...
3,939
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A 35-year-old lady presents with vaginal discharge. Smears from vaginal discharge show presence of?
Ans-A Trichomonas VaginalisThe image shows the presence of the anaerobic flagellated protozoan parasite, which causes vaginitis in women with the development of greenish malodorous discharge.
3,940
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A mother brings her 1 year old child to the hospital with complaints that he turns blue while breastfeeding. It resolves when he assumes a squatting position. On examination, a cleft palate is seen. Labs show hypocalcemia. Which of the following abnormalities are expected to be seen in the lymphoid organs?
Decreased size of paracoical areas of lymph nodes is expected as this child has DiGeorge Syndrome. DiGeorge Syndrome: Deficient CMI is seen due to aplasia of thymus and hence deficiency of T cells. This leads to paracoical areas of lymph nodes and periaeriolar sheaths of the spleen being reduced in size. B cells are us...
3,941
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Length of Posterior vaginal wall is
The anterior wall of the vagina is about 8 cm long and the posterior wall about 10 cm long. ref - BDC 6e vol2 pg 393
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Austin flint murmur is seen in cases of
The Austin Flint murmur of chronic severe AR is a low-pitched mid to late apical diastolic murmur that sometimes can be confused with MS. The Austin Flint murmur typically decreases in intensity after exposure to vasodilators, whereas the murmur of MS may be accompanied by an opening snap and also may increase in inten...
3,943
medmcqa_train
Pheochromocytoma is associated with -
Ans. is 'b' i.e., Cafe-au-lait spots o About 25-33% of patients with a pheochromocytoma or paraganglioma have an inherited syndrome.# Neurofibromatosis type 1 (NF1) was the first described pheochromocytoma-associated syndrome.o The NF1 gene functions as a tumor suppressor by regulating the Ras signaling cascade. Classi...
3,944
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Not a feature of brain death
The structural and functional damage of brain-stem may be diagnosed depending upon the following observations: Dilated fixed pupils, not responding to sharp changes in intensity of incident light. Absence of motor responses within the cranial nerve distribution on painful stimulation. Absence of corneal reflexes. Abse...
3,945
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False statement regarding adductor pollicis muscle:
Ans: B (Supplied by Median nerve) Ref : Gray s Anatomy, 39th edition, 2008.Page.918Explanation:Adductor pollicis:Has 2 heads, i) Obi ique head ii) Transverse headOblique head: Origin from capitate, bases of 2nd, & 3rd metacarpal bonesTransverse head: Origin from palmar surface of 3rd metacarpal honeInsertion: Two heads...
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Testing for microdeletion of Y-chromosome is offered for which patient with a normal Karyotype
A patient with severely decreased sperm counts and a normal Karyotype is offered testing for microdeletion of Y chromosome.
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True statement regarding insulin:
Ref: Harper's Illustrated Biochemistry,28th editionExplanation:InsulinSecreted from pancreatic islet b cellsReleased regulated by blood (glycemic thresholdSynthesized as a single chain : pro-insulinInsulin is formed from proinsulin (removal of the connecting or "C" peptide)Insulin is thus made up of 2 chainsA (21 amino...
3,948
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Nipple shadows in chest xray characteristically have a sharp
Miller et al proposed that solitary pulmonary nodules that reach some or all of the following criteria can be considered nipple shadows :Bilateral and symmetric"fuzzy" margins or radiolucent "halo"Sharp lateral border and poorly defined medial border (may be present only on pa projections 3)Nodules are in a characteris...
3,949
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What changes the conformation of alpha helix in collagen
Ans. (b) ProlineRef: Harper's Biochemistry, 30th ed. pg. 141, 298-99* Proline is the amino acid which changes the conformation of the alpha helix in collagen due to the nature of proline having a cyclical structure. It also forms the ends of the beta sheets in the secondary structures.
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Disruption or disorganization of biological rhythm is observed in
Disturbance of biological functions is common with depression, with insomnia (or sometimes increased sleep), loss of appetite and weight (or sometimes hyperphagia and weight gain), and loss of sexual drive. When the disturbance is severe, it is called as melancholia ( somatic syndrome) The somatic syndrome in depressio...
3,951
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All of the following are features of musculocutaneous nerve injury at axilla except
Loss of flexion of shoulder* Flexion at shoulder is done by major muscles like pectoralis major, anterior fibres of deltoid, which are intact here. Musculocutaneous nerve (MCN)originates from the lateral cord of the brachial plexus of nerves. It pierces the coracobrachialis muscle and gives off branches to the muscle, ...
3,952
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Material used in veebroplasty:
Ans. Polymethyl methacrylate
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Paramesonephric duct in males remains as
The paramesonephric ducts remain rudimentary in the maleThe greater pa of each duct eventually disappearsThe cranial end of each duct persists as a small rounded body attached to the testis(appendix of testis)It has been considered that the prostatic utricle represents the uterovaginal canalRef: Inderbir Singh&;s Human...
3,954
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Following injury to the right temple region, patient complaints of pain in the right eye and loss of vision. On examination the eye movements are normal, and pupil normally reacts to light. The diagnosis is
(C) Traumatic glaucoma# Traumatic Glaucoma: Atraumatic separation to the iris root and citiary body. Is not an uncommon cause of trauma by blunt object or by penetrating injury to globe.> Symptoms: Pain, blurred vision, history of blunt and penetrating injury.> Sings: Hyphaema, an irregular pupil in acute phase, slight...
3,955
medmcqa_train
Under EMCP launched in 1997,the criteria for selection of PHCs included the following EXCEPT:
Under EMCP (Enhanced Malaria Control Project) launched in 1997, the criteria for selection of PHCs (Primary Health Center) include API more than 2 for the last 3 years, Plasmodium falciparum more than 30% of total malaria cases and the area has been reporting deaths.
3,956
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All of the following statements about purification of water are true except :
Spores of Cl. perfrignence (in the absence of coliform group) indicate remote fecal contamination of water. Total coliform bacteria must not be detectable in any 100 ml of sample. Sodium thiosulphate is used to dechlorinate tap water for aquariums or treat effluent from waste water treatments prior to release into rive...
3,957
medmcqa_train
In rhinosporidiosis the following is true:
(c) Surgery is the treatment(Ref. Scott Brown, 6th ed., 4/8/40)Rhinosporidiosis is managed by wide excision and cauterisation of base. Recurrence may occur if sporangium is left behind. Dapsone is given in the postoperative period to decrease the chances of recurrence.
3,958
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A 45-year-old woman is admitted to the emergency department with a complaint of severe abdominal pain. CT scan and MRI examinations reveal a tumor of the head of the pancreas involving the uncinate process. Which of the following vessels is most likely to be occluded?
The superior mesenteric artery arises from the aorta, deep to the neck of the pancreas, then crosses the uncinate process and third part of the duodenum. An uncinate tumor can cause compression of the superior mesenteric artery. The common hepatic artery arises superior to the body of the pancreas and is unlikely to be...
3,959
medmcqa_train
A 35-year-old man presents with following problem. Most likely diagnosis?
Ans. C. Gouta. Acute gout causing swelling, erythema and extreme pain and tenderness of the first metatarsophalangeal joint.b. This is also known as Podagra- Colchicine and indomethacin are the drug of choice in this acute attack.
3,960
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All of the following passthrough lesser sciatic foramen except:
Internal pudendal vessels
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Extrapyramidal side effects of antipsychotics -a) Dystoniab) Akathisiac) Seizuresd) Diarrheae) Parkinsonism
Extrapyramidal side effects of antipsychotics Extrapyramidal side effects are the major dose limiting side effects of antipsychotics. Maximum extrapyramidal side effects are seen with haloperidol. Least extrapyramidal side effects are seen with clozapine (amongst all antipsychotics). Among typical antipsychotics, thi...
3,962
medmcqa_train
Hard exudates are seen in the following except
Leukaemic retinopathy It is characterised by pale and orange fundus background with dilated and touous veins. In later stages, greyish white lines may be seen along the course of the veins (due to perivascular leukaemic infiltration). Aerioles become pale and narrow. Retinal haemorrhages with typical white centre (Roth...
3,963
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A newborn child presents with inverted foot and the dorsum of the foot cannot touch the anterior tibia. The most probable diagnosis is:
Ans. c. CTEV (Ref: Apley's 9/e p291, 591-594; Turek's 6/e p658-661; Campbell's 11/e p1474-1475)The most probable diagnosis in a newborn child with inverted foot in whom the dorsum of the foot cannot touch the anterior tibia is CTEV.Congenital Talipes EquinoVarus (CTEV):Congenital deformity involving one foot or both.Af...
3,964
medmcqa_train
Increase in body temp during ovulation is by -
Ans. is 'b' i.e., Progesterone o Ovulation mav be inferred bv measuring the basal body temperature throuehout the menstrual cycle.o Temperature recordings are done on a chart and sustained upward shift of temperature (0.3degrees F for three days) infers that progesterone is being synthesized and released into circulati...
3,965
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Replacement of etonogestrel implant(Implanon) is normally done after how many years?
Implanon is a single rod subdermal implant with 68 mg of the progestin etonogestrel (ENG), and an ethylene vinyl acetate copolymer cover. It can be used as contraception for 3 years and then replaced at the same site or opposite arm. It is placed in the medial surface of the upper arm 6 to 8 cm from the elbow in the bi...
3,966
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True morbidity in a population can be calculated by
Active Surveillance Extra measures are taken to collect data and confirm diagnoses to ensure more complete repos for surveys and outbreak investigations. Active surveillance encompasses formal and informal communications. Eg: Malaria surveillance by a health worker Main objectives of Surveillance 1. Provide information...
3,967
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A middle aged man came with fever 2 weeks. He also complains of occasional night sweats and has significant weight loss. BAL was done, in which MTB was not detected. Extra pulmonary TB is suspected. Which of the following sites is most likely affected?
Lumph nodes are the most common site of extrapulmonary TB. Associated pulmonary disease is present in fewer than 50% of cases. The diagnosis is established by fine needle aspiration biopsy. Cultures are positive in 70- 80%. In descending order of frequency, the extrapulmonary sites most commonly involved in TB are the ...
3,968
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. A neonate is seen crying with eyes closed and moving all his limbs. What is the Neonatal Behavioral response scale -
Scale 6 Neonatal behavior assessment scale It is a scale developed by T. Berry Brazelton for evaluating the neurological conditions and behavior of newborn by assessing his or her aleness, motor maturity, irritability and interaction with people. Scores SLEEP STATE I)Deep sleep: - Sleep with regular breathing, eyes clo...
3,969
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Ohobaric oxygen is used in
.HYPERBARIC OXYGEN It is administration of oxygen 1 or 2 atmospheres above the atmospheric pressure in a compression chamber. It increases the aerial oxygen saturation so that oxygen perfusion of tissues will be increased.Indications 1. Carbon monoxide poisoning. 2. Tetanus, gas gangrene infections. 3. Bedsores, frostb...
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All are true about Exenatide except -
Ans. is 'c' i.e., Used in type I diabetes mellitus Exenatide is a synthetic glucagon-like peptide -1 (GLP-l) analogue. o It acts similar to GLP-1 --> Enhancement of postprandial insulin release, suppression of glucagon release and appetite as well as slowing of gastric emptying. o It is given by subcutaneous route & us...
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Smallest diameter of pelvis is?
Interspinous diameter REF: Clinical Obstetrics 10th edition by S. Gopalan, Sarala & Jain, Vanita Page 4, Manual of Obstetrics, 3e by Shirish N Daftary Page 11-12, Manual Of Obstetrics (2Nd Edition) by Daftary Page 16-18 "Interspinous diameter (transverse diameter of midpelvis = 10 cm or somewhat more) is the smallest d...
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NSAIDS with least anti inflammatory' action -
Ans. is 'b' i.e., ParacetamolParacetamolo It does not possess anti - inflammatory activity because it is ineffective in the presence of peroxides generated at the site of inflammation.o It produces very little GI toxicity and can be administered in patients intolerant to other NSAIDs.
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H is helpful in all of the following except
.
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Direct fibrinolytics are/is:
Ans. b (Alfimeprase). (Ref. Harrison's medicine 16th ed. 690)Alfimeprase is a metalloproteinase that degrades fibrin in a plasmin-independent fashion. It is a novel thrombolytic based on snake venom derived protein. It is a direct fibrinolytic. It is not a plasminogen activator. It is neutralized by alpha-macroglobulin...
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Drug of choice for sedation of a patient in ICU is: September 2009, March 2013 (a)
Ans. C: Propofol Benzodiazepines, e.g. diazepam, lorazepam and midazolam, are widely used as sedative agents in the ICU. Diazepam use has become less common as newer shoer-acting benzodiazepines have become available. Lorazepam is more potent than midazolam and, because of its low lipid solubility, crosses the blood-br...
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Decreased number of melanocytes are seen in: March 2005
Ans. D: All of the above Melanopenic hypopigmentation is due to decrease in number of melanosomes, which could be due to: Genetic diseases-albinism, piebaldism A utoimmune diseases-vitiligo Post-inflammatory-Discoid lupus erythematosus Piebaldism is due to an absence of melanocytes in affected skin and hair follicles. ...
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A 40 year old patient is suffering from carotid body tumor. Which of the following is the best choice of treatment for him?
Ans. is 'a' i.e., Excision of tumour
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Branchial cyst arises due to-
Ans. is 'a' i.e., Failure of obliteration of second branchial cleft Brachial Cyst* A branchial cleft cyst is a congenital epithelial cyst that arises on the lateral part of the neck usually due to failure of obliteration of the second branchial cleft in embryonic development. Less commonly, the cysts can develop from t...
3,979
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Most common pulmonary manifestation of SLE:
Ans. (b) PleuritisRef: Harrisons Principle of Internal Medicine 20th Ed; Page No- 2520Most Common Complication in SLE* Cutaneous Manifestations:# The most common acute SLE rash: Butterfly" rash# Most common chronic dermatitis in lupus: Discoid lupus erythematosus (DLE)* Vascular Occlusions: Myocardial infarctions are p...
3,980
medmcqa_train
Person having heterozygous sickle cell trait is protected from infection of:
Ans. a. P. falciparum (Ref: Robbins 9/e p390, 8/e p387)Person having heterozygous sickle cell trait is protected from infection of P. falciparum."People who are heterozygous for the sickle cell trait (HbS) become infected with P. falciparum, but they are less likely to die from infectionQ. The HbS trait causes the para...
3,981
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Johne's bacillus is:
M. Paratuberculosis
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A 30 year ols woman presented with secondary amenorrhoea for 3 years along with galactorrhea. The most likely cause of her symptoms would be -
prolactinoma stimulate pituitary causing excessive milk secretion and it also inhibit GnRH causing decreased FSH &LH level causing secondary amenorrhea (Harrison 17 pg 2206)
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Hypercalcemia is caused by all except:
Answer is D (Furosemide): Thiazide diuretics cause hypercalcemia while loop diuretics (furosemide) cause hypocalcemia. Furosemide is a loop diuretic that is characteristically associated with hypocalcemia and not hypercalcemia.
3,984
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All of the following are true regarding chronic active hepatitis, except:
Chronic hepatitis is defined as a chronic inflammatory reaction of the liver of more than 3-6 months duration, demonstrated by persistently abnormal serum aminotransferase levels and characteristic histologic findings. The causes of chronic hepatitis include. HBV, HCV and HDV autoimmune hepatitis, chronic hepatitis ass...
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HLA is present on -
Ans. is 'b' i.e., Sho arm of chromosomes 6 o HLA complex of genes is located on the sho arm of chromosome 6.
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Hemochromatosis affect the following organs
Ans: dRef: Harrison, 16,hed, p. 2301
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SSRI is first-line treatment for
In social phobia, among the antidepressants, SSRIs are currently drugs of choice, with paroxetine being the most widely used drug. Other SSRIs, such as fluoxetine and seraline are also equally effective. Fluoxetine has the advantage of a longer half-life. Other antidepressants such as imipramine (TCA) and phenelzine (M...
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The most common site of primary osteoarthrosis is -
In general, weight bearing lower limb joints are affected more commonly than upper limb joints. However, No textbook has mentioned which is the commonest joint : knee or hip. According to me it is knee because of following facts :- I have seen hardly one or two cases of primary OA of hip; while, I have seen hundreds ...
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The classical example of muscular violence is
B i.e. of patella
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Which of the following sonographic finding suggests development of preeclampsia
Superabundance of chorionicvilli is implicated in etiopathogenesis of preeclampsia.
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Perl's stain or prussion blue test is for:
Perls' stain (Prussian-Blue Reaction) is to demonstrate Ferric salts in tissues. These are seen as iron  granules in bone marrow macrophages, erythroblasts (Sideroblasts) and erythrocytes (Siderocytes) in  blood films and haemosiderin in spun urine.
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Secondary hemorrhage is after how many days of tonsillectomy
Secondary haemorrhage (occur from 3rd day onwards (5th to 10th day higher chances) due to sloughing of aeries caused by infection). It is the result of sepsis and premature separation of membrane. Ref : ENT textbook by Dhingra 6th edition Pgno : 430
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The most common cuase of renal scarring in a 3 year old child is -
Ans. is 'c' i.e., Vesicouretrial reflux induced pyelonephritis The small scarred kidney in childhood;. Risdon RA] `Reflux nephropathy is now a generally accepted term to describe small scarred kidneys discovered during childhood; it recognises the close association between this renal lesion and vesicoureteric reflux (V...
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In chronic inflammation confined to the portal tract with intact limiting membrane and normal lobular parenchyma, the histopathological diagnosis would be -
Intact limiting membrane with inflammation confined to portal area is seen in chronic persistent hepatitis.
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A neonate born to infected hepatitis-B mother, should be treated with:
D. Immunoglobulins and hepatitis-B-vaccine(Ref: Nelson's 20/e p 1942-1952)"Infants born to HbsAg positive mothers should receive both Hep B Ig and Hep B vaccine at separate sites within 12 hours of birth, followed by 2nd and 3rd dose of vaccine at 1 and 6 months.
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Advantage of coho study ?
Ans. is 'd' i.e., More than one outcomes can be studied
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The most earliest sign of anterior uveitis is:
Ans. Aqueous flare
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Ligament of Cooper, used in the surgery for femoral hernia repair, is formed by which of the extentions of inguinal ligament?
Answer-A. Lacunar ligamentIt is also called Gimbernat's ligament.From the medial end, deep fibres curve horizontally backward to the medial side of pectin pubis forming lacunar ligament.This ligament is trainagular in shape, with the apex attached to the pubic tubercle.Its sharp lateral edge forms the medial boundary o...
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