query
stringlengths
17
395
pos
list
neg
list
task
stringclasses
1 value
instruction
dict
Should ascitis volume and anthropometric measurements be estimated in hospitalized alcoholic cirrotics?
[ "Ascitis and undernutrition are frequent complications of cirrhosis, however ascitis volume and anthropometric assessment are not routinely documented or considered in prognostic evaluation. In a homogeneous cohort followed during two years these variables were scrutinized, aiming to ascertain relevance for longter...
[ "While it was thought that all alcoholic beverages share a similar liver toxicity when drunk at a high level, recent epidemiological surveys have suggested that wine drinking might decrease the risk of alcoholic cirrhosis in heavy drinkers. Therefore, we performed a study aiming to analyse the type and the intake l...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
The use of audit to identify maternal mortality in different settings: is it just a difference between the rich and the poor?
[ "To illustrate how maternal mortality audit identifies different causes of and contributing factors to maternal deaths in different settings in low- and high-income countries and how this can lead to local solutions in reducing maternal deaths. Descriptive study of maternal mortality from different settings and rev...
[ "To what extent are outcome measures in endometriosis-related quality of life studies influenced by the setting in which patient recruitment is performed?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Could the extent of lymphadenectomy be modified by neoadjuvant chemotherapy in cervical cancer?
[ "The effect of neoadjuvant chemotherapy (NACT) on topographical distribution patterns of lymph node metastasis in cervical cancer was unknown. Patients with FIGO stage IB1-IIB who underwent radical surgery with or without NACT were enrolled (3527 patients). A matched-case comparison design was used to compare the e...
[ "This article reviews the recent seminal studies in esophagogastric cancer. Regular low aspirin use may reduce the risk of esophagogastric cancer. Laparoscopic resection of locally advanced gastric cancer appears equivalent to open resection. There is no survival benefit for the addition of postoperative radiation ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Do Wound Cultures Give Information About the Microbiology of Blood Cultures in Severe Burn Patients?
[ "Blood stream infection (BSI) and the subsequent development of sepsis are among the most common infection complications occurring in severe burn patients. This study was designed to evaluate the relationship between the burn wound flora and BSI pathogens. Documentation of all bacterial and fungal wound and blood i...
[ "Early diagnosis of Acute Osteomyelitis (OM) and Septic Arthritis (SA) is of vital importance to avoid devastating complications. There is no single laboratory marker which is sensitive and specific in diagnosing these infections accurately. Total Count, ESR and CRP are not specific as they can also be elevated in ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Are behavioural risk factors to be blamed for the conversion from optimal blood pressure to hypertensive status in Black South Africans?
[ "Longitudinal cohort studies in sub-Saharan Africa are urgently needed to understand cardiovascular disease development. We, therefore, explored health behaviours and conventional risk factors of African individuals with optimal blood pressure (BP) (≤ 120/80 mm Hg), and their 5-year prediction for the development o...
[ "To assess the risk of death from coronary heart disease, stroke, all cardiovascular diseases and all-cause mortality associated with pulse pressure among the middle-aged population. A prospective 15-year follow-up cohort study was conducted of two independent cross-sectional random samples of the population who pa...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Systematic use of patient-rated depression severity monitoring: is it helpful and feasible in clinical psychiatry?
[ "The gap between evidence-based treatments and routine care has been well established. Findings from the Sequenced Treatments Alternatives to Relieve Depression (STAR*D) emphasized the importance of measurement-based care for the treatment of depression as a key ingredient for achieving response and remission; yet ...
[ "To what extent are outcome measures in endometriosis-related quality of life studies influenced by the setting in which patient recruitment is performed?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Treadmill training post stroke: are there any secondary benefits?
[ "To explore the secondary benefits of treadmill training for people in the chronic stage of recovery from stroke. Modified random assignment, matched-pair control group design with repeated measures. Outpatient stroke centre. Twenty individuals post first stroke who acknowledged walking slower than pre stroke. Part...
[ "To identify evidence evaluating the effectiveness of physiotherapy in adolescents (>16 years of age) and adults with cerebral palsy. Systematic literature search from the earliest available time until March 2009. Additional studies were identified through reference and citation tracking. Two reviewers independentl...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Does lunar position influence the time of delivery?
[ "To study the relationship between lunar position and the day of delivery; to investigate the synodic distribution of spontaneous deliveries, especially in relation to the presence of a full moon. Retrospective analysis of 1248 spontaneous full-term deliveries in three-year period (36 lunar months), setted at Depar...
[ "Does extended embryo culture have a different effect on the birthweight of girls and boys?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is oral endotracheal intubation efficacy impaired in the helicopter environment?
[ "Patients transported by helicopter often require advanced airway management. The purpose of this study was to determine whether or not the in-flight environment of air medical transport in a BO-105 helicopter impairs the ability of flight nurses to perform oral endotracheal intubation. The study was conducted in a...
[ "There has been a significant increase in premedication use for neonatal intubation in the UK over the past decade. We aimed to determine the adverse events during neonatal intubation using the most commonly used premedication regimen in the UK." ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Prostatic syndrome and pleural effusion: are they different diseases?
[ "To report an uncommon association of prostate and lung cancer. The characteristics of both tumors, their association with tumors in other sites and the time of presentation are analyzed. Both tumors were in the advanced stages. Metastatic carcinoma of the prostate was discarded due to the form of presentation." ]
[ "Tumors and tumorlike lesions of the tubular bones of the hand, often incidentally discovered lesions, present a unique but challenging differential diagnosis." ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Telemedicine and type 1 diabetes: is technology per se sufficient to improve glycaemic control?
[ "Each patient received a smartphone with an insulin dose advisor (IDA) and with (G3 group) or without (G2 group) the telemonitoring/teleconsultation function. Patients were classified as \"high users\" if the proportion of \"informed\" meals using the IDA exceeded 67% (median) and as \"low users\" if not. Also anal...
[ "Is optimal adherence to guideline recommendations in intrauterine insemination (IUI) care cost-effective from a societal perspective when compared with suboptimal adherence to guideline recommendations?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Is controlled ovarian stimulation in intrauterine insemination an acceptable therapy in couples with unexplained non-conception in the perspective of multiple pregnancies?
[ "Controlled ovarian stimulation (COS) with intrauterine insemination (IUI) is a common treatment in couples with unexplained non-conception. Induction of multifollicular growth is considered to improve pregnancy outcome, but it contains an increased risk of multiple pregnancies and ovarian hyperstimulation syndrome...
[ "To evaluate and compare the clinical impact of proximal tubal occlusion and salpingectomy when performed before IVF in patients with hydrosalpinges. Prospective randomized study. Assisted reproduction unit in an obstetrics and gynecology department in a university hospital in Greece as well as assisted reproductio...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is half-dose contrast-enhanced three-dimensional MR angiography sufficient for the abdominal aorta and pelvis?
[ "To evaluate the usefulness of half-dose contrast-enhanced magnetic resonance (MR) angiography for depicting the abdominal aorta and its major branches. A total of 72 consecutive patients were randomly assigned to one of four groups that underwent MR angiography after receiving different concentrations (original or...
[ "The purpose of this study was to investigate whether preoperative 16-MDCT at 0.7-mm collimation can be used to predict the presence of an endarterectomy plane by depicting abnormal thickening of the walls of central pulmonary arteries in patients with chronic thromboembolic pulmonary hypertension. MDCT scans of 40...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Digital Tomosynthesis: A Viable Alternative to Noncontrast Computed Tomography for the Follow-Up of Nephrolithiasis?
[ "Digital tomosynthesis (DT) is a new X-ray-based imaging technique that allows image enhancement with minimal increase in radiation exposure. The purpose of this study was to compare DT with noncontrast computed tomography (NCCT) and to evaluate its potential role for the follow-up of patients with nephrolithiasis ...
[ "To evaluate whether the combination of imaging biomarkers obtained by means of different 3 Tesla (3T) Magnetic Resonance Imaging (MRI) advanced techniques can improve the diagnostic accuracy in the differentiation between benign and malignant single ring-enhancing brain masses. 14 patients presenting at convention...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
High cumulative insulin exposure: a risk factor of atherosclerosis in type 1 diabetes?
[ "Since insulin therapy might have an atherogenic effect, we studied the relationship between cumulative insulin dose and atherosclerosis in type 1 diabetes. We have focused on patients with type 1 diabetes instead of type 2 diabetes to minimise the effect of insulin resistance as a potential confounder. An observat...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Are hepatitis G virus and TT virus involved in cryptogenic chronic liver disease?
[ "Hepatitis G virus can cause chronic infection in man but the role of this agent in chronic liver disease is poorly understood. Little is known about the relation of another newly discovered agent, the TT virus, with chronic liver disease.AIM: To investigate the rate of infection with hepatitis G virus and TT virus...
[ "Hepatitis A virus infection in patients with previously stable chronic liver disease is associated with liver decompensation. Whether infection with hepatitis E virus (HEV) also does so is not known. We studied 32 patients with decompensated liver disease and definite evidence of underlying cirrhosis for evidence ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Do older patients who refuse to participate in a self-management intervention in the Netherlands differ from older patients who agree to participate?
[ "Refusal of patients to participate in intervention programs is an important problem in clinical trials but, in general, researchers devote relatively little attention to it. In this article, a comparison is made between patients who, after having been invited, agreed to participate in a self-management interventio...
[ "Are positive experiences of different aspects of patient-centred care (PCC) associated with higher intentions to comply with fertility treatment?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Preoperative locoregional staging of gastric cancer: is there a place for magnetic resonance imaging?
[ "The aim of this study was to prospectively compare the diagnostic performance of magnetic resonance imaging (MRI), multidetector computed tomography (MDCT) and endoscopic ultrasonography (EUS) in the preoperative locoregional staging of gastric cancer. This study had Institutional Review Board approval, and inform...
[ "The purpose of this study was to evaluate the efficacy of high-resolution axillary ultrasound in detecting axillary lymph node metastases after neoadjuvant chemotherapy in patients with locally advanced breast cancer. Fifty-three patients with stage II or III breast cancer undergoing neoadjuvant chemotherapy who h...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Do familiar teammates request and accept more backup?
[ "The present study investigated factors that explain when and why different groups of teammates are more likely to request and accept backup from one another when needed in an environment characterized by extreme time pressure and severe consequences of error: commercial air traffic control (ATC). Transactive memor...
[ "In order to definitude the influence caused by the different sampling in voice assessment. We comparing the results acquired by total section and subsection sampling. The results acquired by subsection tended to normal more than those acquired by total section." ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Transsphenoidal pituitary surgery in Cushing's disease: can we predict outcome?
[ "To assess the results of transsphenoidal pituitary surgery in patients with Cushing's disease over a period of 18 years, and to determine if there are factors which will predict the outcome. Sixty-nine sequential patients treated surgically by a single surgeon in Newcastle upon Tyne between 1980 and 1997 were iden...
[ "Sellar reconstruction with intrasellar packing following endoscopic resection of pituitary macroadenomas remains a subject of clinical and radiological discussion particularly, when an intraoperative cerebrospinal fluid (CSF) leakage is absent. This study was conducted to contribute our experience with sellar reco...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Can bedside assessment reliably exclude aspiration following acute stroke?
[ "To investigate the ability of a bedside swallowing assessment to reliably exclude aspiration following acute stroke. Consecutive patients admitted within 24 h of stroke onset to two hospitals. A prospective study. Where possible, all patients had their ability to swallow assessed on the day of admission by both a ...
[ "Decreased consciousness is a common reason for presentation to the emergency department (ED) and admission to acute hospital beds. In trauma, a Glasgow Coma Scale score (GCS) of 8 or less indicates a need for endotracheal intubation. Some advocate a similar approach for other causes of decreased consciousness, how...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Are UK radiologists satisfied with the training and support received in suspected child abuse?
[ "A list of telephone numbers of UK hospitals with a radiology department was obtained from the Royal College of Radiologists. One hundred hospitals were then randomly selected for inclusion in the survey. An 18-item questionnaire was successfully administered to consultant radiologists from 84 departments. Sixty-on...
[ "To assess the effectiveness of a 6-month rotation in forensic medicine in developing medicolegal and forensic skills for doctors training for a fellowship with the Australasian College for Emergency Medicine (ACEM). Over a period of 6 years 12 trainees undertook a 6-month rotation with the Victorian Institute of F...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Artefacts in 24-h pharyngeal and oesophageal pH monitoring: is simplification of pH data analysis feasible?
[ "Ambulatory 24-h dual-channel pharyngeal and oesophageal pH monitoring is the standard test for measuring gastro-oesophageal and gastropharyngeal reflux. Artefacts caused by the intake of food may result in falsely positive gastropharyngeal reflux, which necessitates a manual review of 24-h pH data. The purpose of ...
[ "Proton-pump inhibitors are effective at preventing the acid component of gastro-oesophageal refluxate from entering the oesophagus. It is not clear whether proton-pump inhibitors prevent duodenogastro-oesophageal reflux. To measure oesophageal exposure to duodenogastro-oesophageal refluxate while on proton-pump in...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Can the condition of the cell microenvironment of mediastinal lymph nodes help predict the risk of metastases in non-small cell lung cancer?
[ "The aim of this study was to analyze the properties of the immune cell microenvironment of regional lymph nodes (LNs) positive for lung cancer. Twenty-four patients operated on for stages T1 and T2 of the NSCLC, were enrolled in the study. Peripheral blood and LN tissue were obtained from different lymph node site...
[ "Solitary pulmonary lesion poses a diagnostic challenge, especially in patients with a history of malignancy. The purpose of this study was to evaluate the characteristics of solitary pulmonary lesions and the outcome of surgical resection. We retrospectively analyzed 243 patients with a history of cancer who under...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Are wandering and physically nonaggressive agitation equivalent?
[ "The authors examined equivalence of wandering and physically nonaggressive agitation (PNA) as concepts. A cross-sectional correlational design was used. Participants were recruited from 22 nursing homes and 6 assisted living facilities in two states. Ambulatory residents meeting DSM-IV criteria for dementia (N = 1...
[ "A tutorial in the utilization of probabilistic risk analysis to analyze the causes of falls in the ambulatory population of an assisted living community. Review of 9 documented incidents of resident falls and interviews with staff regarding the probability of fall causes. A literature review was also conducted. Ag...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Is size-reducing ascending aortoplasty with external reinforcement an option in modern aortic surgery?
[ "Enlargement of the ascending aorta is often combined with valvular, coronary, or other cardiac diseases. Reduction aortoplasty can be an optional therapy; however, indications regarding the diameter of aorta, the history of dilatation (poststenosis, bicuspid aortic valve), or the intraoperative management (wall ex...
[ "The purpose of this study was to investigate the safety and efficacy of a period of deep hypothermic circulatory arrest (DHCA) during elective replacement of the ascending thoracic aorta. DHCA has been implemented in ascending thoracic aortic aneurysm resection whenever the anatomy or pathology of the aorta or arc...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does depression diagnosis and antidepressant prescribing vary by location?
[ "Studies have linked ethnic differences in depression rates with neighbourhood ethnic density although results have not been conclusive. We looked at this using a novel approach analysing whole population data covering just over one million GP patients in four London boroughs. Using a dataset of GP records for all ...
[ "Aspirin is considered one of the most prescribed drugs worldwide, predominantly for its cardioprotective effects. However, its use may be precluded by gastrointestinal and haematological side-effects. To investigate the association between the prophylactic use of aspirin and the prevalence of anaemia among adults....
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Can routinely collected ambulance data about assaults contribute to reduction in community violence?
[ "The 'law of spatiotemporal concentrations of events' introduced major preventative shifts in policing communities. 'Hotspots' are at the forefront of these developments yet somewhat understudied in emergency medicine. Furthermore, little is known about interagency 'data-crossover', despite some developments throug...
[ "Older patients with chronic cardiac conditions are more vulnerable to falls and injuries. Cardiovascular conditions, prevalent in older people, are also the frequent cause of potentially harmful fall injuries among this group. The need to identify the fall risk-related factors that cluster with arrhythmia and sync...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Volume change of uterine myomas during pregnancy: do myomas really grow?
[ "To estimate changes in uterine myoma volume during pregnancy. Review of departmental electronic perinatal database and medical records. Canadian Task Force Classification II-3. Obstetrical ultrasound unit in an academic tertiary care center. One hundred-seven patients diagnosed with uterine myomas during pregnancy...
[ "Is small uterine cavity size as assessed by ultrasonography associated with bleeding problems or pain in nulligravid women using intrauterine contraception, or do other factors affect these parameters?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is laparoscopic adrenalectomy safe and effective for adrenal masses larger than 7 cm?
[ "Laparoscopic adrenalectomy (LA) has become the gold standard treatment for small (less than 6 cm) adrenal masses. However, the role of LA for large-volume (more than 6 cm) masses has not been well defined. Our aim was to evaluate, retrospectively, the outcome of LA for adrenal lesions larger than 7 cm. 18 consecut...
[ "Mucinous cystic neoplasms (MCN) of the pancreas frequently develop in the distal pancreases of young women. Laparoscopic surgery can enhance cosmetic benefits and ease of surgery. This study assessed the feasibility of laparoscopic surgery for MCN. The medical records of 21 patients pathologically diagnosed with b...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Upstream solutions: does the supplemental security income program reduce disability in the elderly?
[ "The robust relationship between socioeconomic factors and health suggests that social and economic policies might substantially affect health, while other evidence suggests that medical care, the main focus of current health policy, may not be the primary determinant of population health. Income support policies a...
[ "The Medicare Prescription Drug, Improvement, and Modernization Act, signed into law in 2003, provided access to prescription drugs for elderly Americans. The Part D benefit continues to evolve. Changes in plan designs, the impact of the doughnut hole on beneficiaries, and increased cost shifting have the potential...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Profiling quality of care: Is there a role for peer review?
[ "We sought to develop a more reliable structured implicit chart review instrument for use in assessing the quality of care for chronic disease and to examine if ratings are more reliable for conditions in which the evidence base for practice is more developed. We conducted a reliability study in a cohort with patie...
[ "Co-occurring mental health and substance use disorders (COD) are the norm rather than the exception. It is therefore critical that performance measures are developed to assess the quality of care for individuals with COD irrespective of whether they seek care in mental health systems or substance abuse systems or ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Eyelid-parotid metastasis: do we screen for coexisting masses?
[ "To report three cases illustrating that it is not unusual for a primary eyelid tumour to metastasise to the parotid gland and vice versa. Two patients with malignant parotid tumours underwent radical parotidectomy and presented subsequently with eyelid lesions. Biopsy showed that both eyelid lesions were histologi...
[ "Although congenital bronchogenic cysts in the cervical region, especially in the thyroid or perithyroidal area, are rare, distinguishing them from other cervical cystic lesions (e.g., thyroglossal duct and branchial cleft cysts) and metastatic cervical lymph nodes is difficult preoperatively. Additionally, cystic ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Will CT ordering practices change if we educate residents about the potential effects of radiation exposure?
[ "The aim of this study was to determine if educating residents about the potential effects of radiation exposure from computed tomographic (CT) imaging alters ordering patterns. This study also explored whether referring physicians are interested in radiation education and was an initial effort to address their CT ...
[ "CT colonography (CTC) has been fully validated as an accurate screening test for colorectal carcinoma and is being disseminated globally. There is an abundance of new literature addressing the prior concerns of the U.S. Preventive Services Task Force and the Centers for Medicare & Medicaid Services. Specific areas...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does context matter for the relationship between deprivation and all-cause mortality?
[ "A growing body of research emphasizes the importance of contextual factors on health outcomes. Using postcode sector data for Scotland (UK), this study tests the hypothesis of spatial heterogeneity in the relationship between area-level deprivation and mortality to determine if contextual differences in the West v...
[ "The current study had two aims: (1) to investigate whether single-item measures of subjective evaluation of neighborhood (i.e., perceived neighborhood safety and quality) predict long-term risk of mortality and (2) to test whether these associations depend on race and gender. The data came from the Americans' Chan...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Does stress increase imitation of drinking behavior?
[ "That alcohol consumption is strongly influenced by the drinking behavior of social company has been demonstrated in observational research. However, not everyone is equally vulnerable to other people's drinking, and it is important to unravel which factors underlie these individual differences. This study focuses ...
[ "Decisions involving risk often must be made under stressful circumstances. Research on behavioral and brain differences in stress responses suggest that stress might have different effects on risk taking in males and females. In this study, participants played a computer game designed to measure risk taking (the B...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
School food policy at Dutch primary schools: room for improvement?
[ "Schools can play an important role in the prevention of obesity, e.g. by providing an environment that stimulates healthy eating habits and by developing a food policy to provide such an environment. The effectiveness of a school food policy is affected by the content of the policy, its implementation and its supp...
[ "The UK Government introduced a large-scale early childhood intervention programme, Sure Start, in 1999. Sure Start is to be further expanded, to achieve national coverage. US experience is highly relevant for anticipating challenges that this expansion will raise. This is a focused, narrative review. We examine th...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is the atopy patch test with house dust mites specific for atopic dermatitis?
[ "The atopy patch test (APT), namely the patch test with aeroallergens, is regarded as specific for patients with atopic dermatitis (AD), but small numbers of positive APT were reported in the past also in atopic subjects without dermatitis and in healthy persons. The aim of this study was to evaluate the response t...
[ "The relationship between hypersensitivity to NSAID and atopic status is still incompletely defined. Previous studies found a high prevalence of atopic diseases in multiple NSAID reactors. The present study aimed to investigate whether this is the case also in Italian adults hypersensitive to NSAIDs. Skin tests wit...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Juvenile osteochondritis dissecans: is it a growth disturbance of the secondary physis of the epiphysis?
[ "The primary physis is responsible for longitudinal bone growth. Similarly, epiphysial growth relies on endochondral ossification from the circumferential secondary physeal [corrected]. injury can result in disruption of normal ossification. The cause of juvenile osteochondritis dissecans (OCD) remains elusive. We ...
[ "Statements have been made in the literature and in legal testimony that misrepresent the radiographic finding of concave distal end of the ulnar metaphysis. To demonstrate that a concave distal end of the ossified ulna in infancy can be normal. Eighty distal wrists of randomly selected infants in the first year of...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Do preoperative statins reduce atrial fibrillation after coronary artery bypass grafting?
[ "Recent studies have demonstrated that statins have pleiotropic effects, including anti-inflammatory effects and atrial fibrillation (AF) preventive effects. The objective of this study was to assess the efficacy of preoperative statin therapy in preventing AF after coronary artery bypass grafting (CABG). 221 patie...
[ "Atheroembolic complications associated with clamping a severely diseased ascending aorta during aortic valve replacement may result in unacceptable mortality and morbidity. Different management options include hypothermic circulatory arrest to replace the aortic valve, an aortic endarterectomy, or tube graft repla...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is there a uniform basal endometrial gene expression profile during the implantation window in women who became pregnant in a subsequent ICSI cycle?
[ "To understand which genes are really involved in the implantation process, we planned to study the gene basal expression profile during the window of implantation (WOI) of patients who became pregnant in a subsequent ICSI cycle. Women attending their first ICSI cycle at ANDROS Day Surgery for severe male factor in...
[ "Ovarian hyperstimulation syndrome (OHSS) is a result of ovarian overexpression of vascular endothelial growth factor (VEGF) and its receptor 2 (VEGFR2). VEGF/VEGFR2 binding disrupts cellular junctions and increases vascular permeability (VP), a characteristic of OHSS, but enhances angiogenesis, which is a fundamen...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Can decisional algorithms replace global introspection in the individual causality assessment of spontaneously reported ADRs?
[ "In this study, an expert panel assessed causality of adverse reports by using the WHO global introspection (GI) method. The same reports were independently assessed using 15 published algorithms. The causality assessment level 'possible' was considered the lower limit for a report to be considered to be drug relat...
[ "To what extent do patient- and treatment-related factors explain the variation in morphokinetic parameters proposed as embryo viability markers?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Can we rely on arterial line sampling in performing activated plasma thromboplastin time after cardiac surgery?
[ "Arterial catheters are routinely used to sample blood for clotting studies in most cardiothoracic intensive care units. The clotting profile in surgical bleeding after cardiac surgery influences further management. Aspiration and discard of a certain amount of blood from the line, prior to sampling, are assumed to...
[ "Thromboembolic stroke is the most common severe complication following coil embolization of intracerebral aneurysms, with a 5% incidence of permanent deficits. Despite heparin anticoagulation, rescue therapy with the platelet glycoprotein IIb/IIIa receptor antagonist abciximab may be required. However, we describe...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Does timing of initial surfactant treatment make a difference in rates of chronic lung disease or mortality in premature infants?
[ "To compare two treatment strategies in preterm infants with or at risk of respiratory distress syndrome: early surfactant administration (within one hour of birth) versus late surfactant administration, in a geographically defined population. The primary outcome was chronic lung disease (CLD) and mortality before/...
[ "Evidence is contradictory whether very low-birth-weight (VLBW, birth weight <1500 g) infants with early neutropenia (NP), especially those born to mothers with preeclampsia experience a greater incidence of nosocomial infection (NI). To investigate whether NP within the first 7 days of life is a risk factor for NI...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Clinician assessment for acute chest syndrome in febrile patients with sickle cell disease: is it accurate enough?
[ "To determine whether the use of empiric chest radiography (CXR) is of significant value in detecting clinically unsuspected acute chest syndrome (ACS) in febrile patients with sickle cell disease (SCD). Patients with SCD presenting to the emergency department and hematology clinic with temperature greater than or ...
[ "Among older children with sickle cell anemia, leukocyte counts, hemoglobin, and reticulocytosis have previously been suggested as disease severity markers. Here we explored whether these blood parameters may be useful to predict early childhood disease severity when tested in early infancy, defined as postnatal ag...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Outcome Feedback within Emergency Medicine Training Programs: An Opportunity to Apply the Theory of Deliberate Practice?
[ "Outcome feedback is the process of learning patient outcomes after their care within the emergency department. We conducted a national survey of Canadian Royal College emergency medicine (EM) residents and program directors to determine the extent to which active outcome feedback and follow-up occurred. We also co...
[ "To discuss the elements of interdisciplinary research and to analyze its contribution to (bio)medical informatics. Commenting on 'Informatics and Medicine - From Molecules to Populations' from K. A. Kuhn et al. in this issue of Methods of Information in Medicine. Referring to examples of successfully established i...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Can multiple SNP testing in BRCA2 and BRCA1 female carriers be used to improve risk prediction models in conjunction with clinical assessment?
[ "Several single nucleotide polymorphisms (SNPs) at different loci have been associated with breast cancer susceptibility, accounting for around 10% of the familial component. Recent studies have found direct associations between specific SNPs and breast cancer in BRCA1/2 mutation carriers. Our aim was to determine ...
[ "No formal assessment of life expectancy in women with BRCA1 and BRCA2 mutations in these genes has been reported previously. We have evaluated life expectancy using actuarial analysis and assessed the effect of breast and ovarian cancers on premature death in >1,000 BRCA1/2 carriers. Families with pathogenic mutat...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Does a special interest in laparoscopy affect the treatment of acute cholecystitis?
[ "We tested the hypothesis that the treatment of patients with acute cholecystitis (AC) would be improved under the care of laparoscopic specialists. The records of patients undergoing cholecystectomy for AC from 1 January 1996 to 31 December 1998 were reviewed retrospectively. Of 170 patients, 48 were cared for by ...
[ "Patients who are suspected of having acute appendicitis usually undergo surgery in order to avoid life-threatening complications such as perforation and peritonitis. However, acute appendicitis is difficult to distinguish from other sources of right-sided abdominal pain. The clinical picture is almost indistinguis...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Can progression of valvar aortic stenosis be predicted accurately?
[ "It was the aim of the present study to elaborate criteria for the assessment of rapid hemodynamic progression of valvar aortic stenosis. These criteria are of special importance when cardiac surgery is indicated for other reasons but the established criteria for aortic valve replacement are not yet fulfilled. Such...
[ "A discrete subaortic membrane cannot only cause left ventricular outflow tract obstruction, but can grow onto the aortic valve leaflets. The late finding of this encroachment is aortic valve insufficiency or stenosis. Echocardiography is used to follow the progression of outflow tract obstruction, but its ability ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Does automatic transmission improve driving behavior in older drivers?
[ "Most older drivers continue to drive as they age. To maintain safe and independent transport, mobility is important for all individuals, but especially for older drivers. The objective of this study was to investigate whether automatic transmission, compared with manual transmission, may improve the driving behavi...
[ "ESC (Electronic Stability Control) is a crash avoidance technology that reduces the likelihood of collisions involving loss of control. Although past and emerging research indicates that ESC is effective in reducing collision rates and saving lives, and its inclusion in all vehicle platforms is encouraged, drivers...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Birth characteristics and risk of low intellectual performance in early adulthood: are the associations confounded by socioeconomic factors in adolescence or familial effects?
[ "In this study we investigated whether the association between measures of fetal growth restriction and intellectual performance was mediated by socioeconomic or familial factors. This was a population-based cohort study of 357,768 Swedish males born as singletons without congenital malformations between 1973 and 1...
[ "Affecting 19% of women, postpartum depression is a major concern to the immediate health of mothers and infants. In the long-term, it has been linked to the development of early-onset asthma at school entry, but only if the depression persists beyond the postnatal period. No studies have tested whether association...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Is scintigraphy a guideline method in determining amputation levels in diabetic foot?
[ "In this study, we aimed to evaluate the potential use of a 3-phase bone scintigraphy method to determine the level of amputation on treatment cost, morbidity and mortality, reamputation rates, and the duration of hospitalization in diabetic foot. Thirty patients who were admitted to our clinic between September 20...
[ "To report the outcomes of surgical treatment of lower limb fractures in patients with chronic spinal cord injuries. A total of 37 lower limb fractures were treated from 2003 to 2010, of which 25 fractures were treated surgically and 12 orthopaedically. Patients of the surgical group had better clinical results, ra...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Is determination between complete and incomplete traumatic spinal cord injury clinically relevant?
[ "Prospective multicenter longitudinal cohort study. To validate the prognostic value of the acute phase sacral sparing measurements with regard to chronic phase-independent ambulation in patients with traumatic spinal cord injury (SCI). European Multicenter Study of Human Spinal Cord Injury (EM-SCI). In 432 patient...
[ "To report the outcomes of surgical treatment of lower limb fractures in patients with chronic spinal cord injuries. A total of 37 lower limb fractures were treated from 2003 to 2010, of which 25 fractures were treated surgically and 12 orthopaedically. Patients of the surgical group had better clinical results, ra...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Improvements in survival of gynaecological cancer in the Anglia region of England: are these an effect of centralisation of care and use of multidisciplinary management?
[ "Our hypothesis is that the adoption of Department of Health (DH) guidance has led to an improvement in outcome in gynaecological cancer survival. In 1999 the DH in England introduced the Improving Outcomes in Gynaecological Cancer guidance, advising case management by multidisciplinary teams with surgical concentr...
[ "To examine whether patients with gastric cancer diagnosed via open-access gastroscopy (OAG) differ in their outcomes compared with patients referred conventionally to outpatient clinics or as acute emergencies. Prospective observational study in the gastroenterology and surgical units of a large district general h...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Do symptoms matter when considering patients for phase I clinical trials?
[ "Older adults (OA) with advanced cancer (AC) undergoing phase I clinical trials (PICT) have poor prognosis. There are no studies which describe symptoms experienced by OA. Retrospective chart review of PICT participants>60 years. OA were compared by age (>65 vs 60-65) and by number of symptoms (>3 vs ≤3). N = 56. M...
[ "To what extent are outcome measures in endometriosis-related quality of life studies influenced by the setting in which patient recruitment is performed?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is vitamin D insufficiency or deficiency related to the development of osteochondritis dissecans?
[ "The aetiology of osteochondritis dissecans is still unclear. The aim of this prospective pilot study was to analyse whether vitamin D insufficiency, or deficiency, might be a contributing etiological factor in the development of an OCD lesion. The serum level of vitamin D3 in 23 consecutive patients (12 male and 1...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Do episodic migraineurs selectively attend to headache-related visual stimuli?
[ "To assess pain-related attentional biases among individuals with episodic migraine. Prior studies have examined whether chronic pain patients selectively attend to pain-related stimuli in the environment, but these studies have produced largely mixed findings and focused primarily on patients with chronic musculos...
[ "Unexplained neurological symptoms (\"somatoform dissociation\") are common in health care settings and associated with disproportionately high levels of distress, disability, and resource utilization. Theory suggests that somatoform dissociation is associated with disturbed attentional processing, but there is a p...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Mitral replacement or repair for functional mitral regurgitation in dilated and ischemic cardiomyopathy: is it really the same?
[ "This was a study to compare the results of mitral valve (MV) repair and MV replacement for the treatment of functional mitral regurgitation (MR) in advanced dilated and ischemic cardiomyopathy (DCM). One-hundred and thirty-two patients with severe functional MR and systolic dysfunction (mean ejection fraction 0.32...
[ "Cardiac Resynchronization Therapy (CRT) is indicated for the treatment of advanced heart failure with severe systolic dysfunction and intraventricular conduction delay. Patient selection for this technology is vital, though it remains unclear which patients benefit most from CRT. We tested the hypothesis that pati...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Do nontriploid partial hydatidiform moles exist?
[ "To study whether nontriploid partial hydatidiform moles truly exist. We conducted a reevaluation of pathology and ploidy in 19 putative nontriploid partial hydatidiform moles using standardized histologic diagnostic criteria and repeat flow cytometric testing by the Hedley technique. On review of the 19 moles, 53%...
[ "To determine some of the unresolved questions related to chromosome anomalies in early human embryos, such are the detection of any advanced maternal age effect; the complete assessment of mosaicism, which requires analysis of all cells; and the relationship with embryonic dysmorphism. Fluorescence in situ hybridi...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is cholecystectomy really an indication for concomitant splenectomy in mild hereditary spherocytosis?
[ "Children referred with symptomatic gallstones complicating HS between April 1999 and April 2009 were prospectively identified and reviewed retrospectively. During this period, the policy was to undertake concomitant splenectomy only if indicated for haematological reasons and not simply because of planned cholecys...
[ "Bilioenteric fistulas are rare complications of cholecystolithiasis that are associated with high morbidity and mortality and mainly appear in elderly patients. This is the report of a patient suffering from cholecystoduodenal fistula with additional cholecystocolonic fistula." ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does surgery or radiation therapy impact survival for patients with extrapulmonary small cell cancers?
[ "Extrapulmonary small cell carcinomas (EPSCC) are rare tumors where therapy remains poorly defined. We sought to determine the impact of surgical extirpation and radiation therapy for outcomes of EPSCC. The Surveillance, Epidemiology, and End Results (SEER) database was queried for patients with EPSCC which were fu...
[ "The outcomes of lung cancer patients who were asymptomatic at diagnosis have never been reported as part of a large-scale study. A national survey of lung cancer in South Korea registered a total of 8788 patients diagnosed in 2005. We report the results herein, with an emphasis on the prognosis of the asymptomatic...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
MR Diagnosis of Bone Metastases at 1.5 T and 3 T: Can STIR Imaging Be Omitted?
[ "To date, no prospective comparative study of the diagnostic value of STIR versus T1-weighted (T1w) sequences at both 1.5 T and 3 T has been performed with special focus on the detectability of bone metastases. 212 oncological patients had a whole-body MRI at 1.5 T and/or at 3 T. The standard protocol comprised STI...
[ "Early diagnosis of Acute Osteomyelitis (OM) and Septic Arthritis (SA) is of vital importance to avoid devastating complications. There is no single laboratory marker which is sensitive and specific in diagnosing these infections accurately. Total Count, ESR and CRP are not specific as they can also be elevated in ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Histologic evaluation of the testicular remnant associated with the vanishing testes syndrome: is surgical management necessary?
[ "There is controversy surrounding the optimal management of the testicular remnant associated with the vanishing testes syndrome. Some urologists advocate the need for surgical exploration, whereas others believe this is unnecessary. These differing opinions are based on the variable reports of viable germ cell ele...
[ "To determine the histopathological differences after varicocele repair in testicular tissue in males with nonobstructive azoospermia. Between 2009 and 2014, 45 men with complete azoospermia and palpable varicocele, presenting with primary infertility of at least 1 year, undergoing varicocele repair at our institut...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Does pain intensity predict a poor opioid response in cancer patients?
[ "A secondary analysis of one-hundred-sixty-seven patients referred for treatment of cancer-related pain was conducted. Pain intensity at admission was recorded and patients were divided in three categories of pain intensity: mild, moderate and severe. Patients were offered a treatment with opioid dose titration, ac...
[ "Opioids are frequently used for the postoperative treatment of chronic disabling occupational musculoskeletal disorders. In many such cases, long-term opioid use persists because of patient requests for ongoing pain relief. Little is known about the relationship between chronic opioid use and functional recovery i...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Do prerecorded lecture VODcasts affect lecture attendance of first-yearpre-clinical Graduate Entry to Medicine students?
[ "There is increasing concern amongst educators that the provision of recorded lectures may reduce student attendance of live lectures. We therefore sought to determine if the provision of prerecorded lecture video podcasts (VODcasts) to first-year Graduate Entry to Medicine (GEM) students, affected attendance at 21...
[ "To reduce nursing shortages, accelerated nursing programs are available for domestic and international students. However, the withdrawal and failure rates from these programs may be different than for the traditional programs. The main aim of our study was to improve the retention and experience of accelerated nur...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is there an intrauterine influence on obesity?
[ "It has been suggested that increasing obesity levels in young women lead to intrauterine environments that, in turn, stimulate increased obesity among their offspring, generating an intergenerational acceleration of obesity levels. If this mechanism is important, the association of maternal body mass index (BMI) w...
[ "Is there a relationship between the genetic risk for polycystic ovary syndrome (PCOS) and genetic variants that influence timing of menopause?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Assessing Patient Reported Outcomes Measures via Phone Interviews Versus Patient Self-Survey in the Clinic: Are We Measuring the Same Thing?
[ "Longitudinally following patients requires a full-time employee (FTE)-dependent data inflow infrastructure. There are efforts to capture patient-reported outcomes (PROs) by the use of non-FTE-dependent methodologies. In this study, we set out to assess the reliability of PRO data captured via FTE-dependent compare...
[ "Parents often accompany adolescent and young adult (AYA) pediatric cancer survivors to follow-up oncology clinic visits and remain involved in their care, although little is known about their reasons for doing so. This mixed methods (qualitative-quantitative) study of 76 mothers of AYA survivors of childhood cance...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is cytokeratin immunoreactivity useful in the diagnosis of short-segment Barrett's oesophagus in Korea?
[ "Cytokeratin 7/20 staining has been reported to be helpful in diagnosing Barrett's oesophagus and gastric intestinal metaplasia. However, this is still a matter of some controversy. To determine the diagnostic usefulness of cytokeratin 7/20 immunostaining for short-segment Barrett's oesophagus in Korea. In patients...
[ "Intestinal metaplasia in the tubular esophagus is the recognized precancerous lesion of adenocarcinoma in Barrett esophagus. However, it is not yet clear whether adenocarcinoma of the gastric cardia arises from the same premalignant lesion, i.e., intestinal metaplasia of the gastric cardia. The purpose of this stu...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is routine dissection of the station 9 lymph nodes really necessary for primary lung cancer?
[ "Mediastinal lymph node dissection is an essential component of lung cancer surgery; however, choosing mediastinal lymph nodes stations to be dissected is subjective. We carried out this research to investigate the need for dissection of station 9 lymph nodes during lung cancer surgery. Patients with primary lung c...
[ "The rising incidence of melanoma and the high prevalence of breast cancer have generated a new scientific problem-how do the regional lymph node basins function after radical lymphadenectomy and are lymphatic drainage patterns altered after radical lymphadenectomy? Furthermore, after radical lymphadenectomy, selec...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Cutaneous melanoma in a multiethnic population: is this a different disease?
[ "Cutaneous melanoma in nonwhite persons has a manifestation and a prognosis that are different than those of cutaneous melanoma in white persons. Case series. Tertiary care university-affiliated community medical center located in a multiethnic state in which white persons are a minority of the population. Consecut...
[ "There exists a strong belief among physicians and the lay public that pregnancy adversely affects survival in patients with melanoma. The authors asked if there was any evidence to support this in patients with clinically localized disease. The authors reviewed the published literature on MEDLINE. The authors foun...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Marital status, living arrangement and mortality: does the association vary by gender?
[ "Men appear to benefit more from being married than women with respect to mortality in middle age. However, there is some uncertainty about gender differences in mortality risks in older individuals, widowed, divorced and single individuals and about the impact of living arrangements. Longitudinal data with 1990 ce...
[ "The current study had two aims: (1) to investigate whether single-item measures of subjective evaluation of neighborhood (i.e., perceived neighborhood safety and quality) predict long-term risk of mortality and (2) to test whether these associations depend on race and gender. The data came from the Americans' Chan...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Does somatostatin confer insulinostatic effects of neuromedin u in the rat pancreas?
[ "Neuromedin U (NmU) is a neuropeptide with anorexigenic activity. Two receptor subtypes (NmUR1 and NmUR2) confer the effects of NmU on target cells. We have recently demonstrated that NmU reduces insulin secretion from isolated pancreatic islets. Aim of our current study is to investigate the role of somatostatin a...
[ "Glucagon-like peptide-1 (GLP-1) promotes glucose homeostasis through regulation of islet hormone secretion, as well as hepatic and gastric function. Because GLP-1 is also synthesized in the brain, where it regulates food intake, we hypothesized that the central GLP-1 system regulates glucose tolerance as well. We ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Kell alloimmunization in pregnancy: associated with fetal thrombocytopenia?
[ "Kell haemolytic disease in pregnancies has been suggested to be associated with decreased fetal platelet counts. The aim of this study was to evaluate the incidence and clinical significance of fetal thrombocytopenia in pregnancies complicated by Kell alloimmunization. In this retrospective cohort study, fetal pla...
[ "Hemophagocytic syndrome (HPS) is mainly characterized by massive infiltration of bone marrow by activated macrophages and often presents with pancytopenia. Thrombotic microangiopathy (TMA) is also present with thrombocytopenia and renal involvement. Both conditions could coexist with each other and complicate the ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Application of computer-aided diagnosis (CAD) in MR-mammography (MRM): do we really need whole lesion time curve distribution analysis?
[ "The identification of the most suspect enhancing part of a lesion is regarded as a major diagnostic criterion in dynamic magnetic resonance mammography. Computer-aided diagnosis (CAD) software allows the semi-automatic analysis of the kinetic characteristics of complete enhancing lesions, providing additional info...
[ "To demonstrate that unsupervised assessment of abdominal adipose tissue distribution by magnetic resonance imaging (MRI) can be improved by integrating automatic correction of signal inhomogeneities. Twenty subjects (body mass index [BMI] 23.7-44.0 kg/m(2)) underwent abdominal (32 slices) MR imaging with a 1.9T El...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Vaccine protection in the elderly: are Austrian seniors adequately protected by vaccinations?
[ "The aim of the study was to evaluate, if elderly persons are sufficiently protected against infectious diseases by vaccination. 300 elderly (>60 years) and 300 young (<35 years) persons from five Austrian cities were recruited according to the criteria of a field study. Antibody concentrations against tetanus, dip...
[ "Influenza virus types A and B cause yearly outbreaks of respiratory tract infections in all age groups including children and adolescents. Complications, such as high fever, febrile convulsions, secondary bacterial infections and myositis frequently lead to hospitalisation. Safe and effective split, subunit and vi...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Vitamin D supplementation and regulatory T cells in apparently healthy subjects: vitamin D treatment for autoimmune diseases?
[ "Epidemiological data show significant associations of vitamin D deficiency and autoimmune diseases. Vitamin D may prevent autoimmunity by stimulating naturally occurring regulatory T cells. To elucidate whether vitamin D supplementation increases Tregs frequency (%Tregs) within circulating CD4+ T cells. We perform...
[ "Slightly more than 5 % of the United States population heavily consumes ethanol, i.e., more than 14 drinks for men and 7 drinks for women a week. Chronic ethanol consumption can result in increased liver disease, reduced recovery from burn injury, and more frequent and severe respiratory infections. Chronic ethano...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Gynecological cancer alarm symptoms: is contact with specialist care associated with lifestyle and socioeconomic status?
[ "The aim of this study was to determine the proportion of patients who were referred to specialist care after reporting gynecological cancer alarm symptoms to their general practitioner. We sought to investigate whether contact with specialist care was associated with lifestyle factors or socioeconomic status. Nati...
[ "Patient-oncologist alliance and psychosocial well-being have strong associations with adherence to cancer management. For patients with cancer of unknown primary (CUP), adherence is crucial to treatment or occult primary screening plans. There has been no study investigating the relationship between alliance, psyc...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does elective re-siting of intravenous cannulae decrease peripheral thrombophlebitis?
[ "Peripheral venous thrombophlebitis (PVT) is a common complication of intravenous cannulation, occurring in about 30% of patients. We evaluated the effect of elective re-siting of intravenous cannulae every 48 hours on the incidence and severity of PVT in patients receiving intravenous fluids/drugs. We randomized 4...
[ "To study the risks of haemodynamic instability, and the possible occurrence of spinal haematoma, meningitis and epidural abscess when epidural analgesia is performed for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). We retrospectively analyzed the data of 35 patients treated by HIPEC...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Can third trimester ultrasound predict the presentation of the first twin at delivery?
[ "To determine the ability of early sonogram to predict the presentation of twin A at birth. A retrospective cohort study was conducted on all twin pregnancies evaluated at our Fetal Evaluation Unit from 2007 to 2009. Sonogram records were reviewed for the presentation of twin A at seven gestational age intervals an...
[ "Does extended embryo culture have a different effect on the birthweight of girls and boys?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Risk factors for major depression during midlife among a community sample of women with and without prior major depression: are they the same or different?
[ "Women's vulnerability for a first lifetime-onset of major depressive disorder (MDD) during midlife is substantial. It is unclear whether risk factors differ for first lifetime-onset and recurrent MDD. Identifying these risk factors can provide more focused depression screening and earlier intervention. This study ...
[ "The long-term impact of a past alcohol use disorder (AUD) among those who are currently in stable remission has not been well-explored. This study examined whether a past history of AUD was associated with increased risk for chronic medical conditions in a large U.S. nationally representative sample of adults ≥30 ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Totally implantable venous access device placement by interventional radiologists: are prophylactic antibiotics necessary?
[ "To determine the rate of early infection for totally implantable venous access devices (TIVADs) placed without antibiotic prophylaxis. A list of patients who underwent TIVAD placement in 2009 was obtained from the patient archiving and communication system (PACS). This list was cross-referenced to all patients who...
[ "Statins are an essential component of the therapeutic approach of patients with atherosclerotic disease. Statin use is also associated with improved peri-operative and long-term outcomes in these patients. We aimed to define the role of statin treatment in patients undergoing percutaneous revascularization procedu...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Starting insulin in type 2 diabetes: continue oral hypoglycemic agents?
[ "To evaluate the effects of insulin 30/70 twice daily or bedtime isophane (NPH) insulin plus continued sulfonylurea and metformin in patients with type 2 diabetes in primary care. Open-label, randomized trial. Persons younger than 76 years with type 2 diabetes whose disease had not been controlled with oral hypogly...
[ "The main goal of this study was to determine the effects of incretins on type 2 diabetes (T2D) remission after Roux-en-Y gastric bypass (RYGB) surgery for patients taking insulin. Type 2 diabetes is a chronic disease with potentially debilitating consequences. RYGB surgery is one of the few interventions that can ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Clinical identifiers for early-stage primary/idiopathic adhesive capsulitis: are we seeing the real picture?
[ "Adhesive capsulitis is often difficult to diagnose in its early stage and to differentiate from other common shoulder disorders. The aim of this study was to validate any or all of the 8 clinical identifiers of early-stage primary/idiopathic adhesive capsulitis established in an earlier Delphi study. This was a cr...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Does delaying surgery in immature adolescent idiopathic scoliosis patients with progressive curve, lead to addition of fusion levels?
[ "To analyze the changes in the curve extent, pattern and the fusion level in adolescent idiopathic scoliosis (AIS) patients who undergo delayed surgery instead of early surgery. Thirty-five immature AIS patients whose radiographs demonstrated an initial primary curve of more than 40° with a subsequent increase of 1...
[ "Retrospective review-multicenter database. The purpose of this study was to compare the upper thoracic (UT) and lower thoracic (LT) upper instrumented vertebrae (UIV) in long fusions to the sacrum for adult scoliosis. The optimal UIV for stopping long fusions to the sacrum/pelvis are controversial. Although a UT e...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Bactericidal activity of 3 cutaneous/mucosal antiseptic solutions in the presence of interfering substances: Improvement of the NF EN 13727 European Standard?
[ "There is no standard protocol for the evaluation of antiseptics used for skin and mucous membranes in the presence of interfering substances. Our objective was to suggest trial conditions adapted from the NF EN 13727 standard, for the evaluation of antiseptics used in gynecology and dermatology. Three antiseptic s...
[ "Glycerol in alcohol-based hand rubs has positive effects on skin condition and user acceptability, but, to the authors' knowledge, its effect on the bactericidal effect of alcohol-based pre-operative hand rubs has not been reported. To investigate the impact of glycerol on the reduction of resident hand flora by e...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Empiric treatment of uncomplicated urinary tract infection with fluoroquinolones in older women in Israel: another lost treatment option?
[ "Current guidelines for the treatment of uncomplicated urinary tract infection (UTI) in women recommend empiric therapy with antibiotics for which local resistance rates do not exceed 10-20%. We hypothesized that resistance rates of Escherichia coli to fluoroquinolones may have surpassed this level in older women i...
[ "Urinary tract infections (UTIs) in women comprise uncomplicated and complicated UTIs. Uncomplicated UTIs, such as acute uncomplicated cystitis and pyelonephritis, are very common infections in otherwise healthy women, with a high tendency to recur. Although severe complications are rare, their high prevalence caus...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Do risk calculators accurately predict surgical site occurrences?
[ "Current risk assessment models for surgical site occurrence (SSO) and surgical site infection (SSI) after open ventral hernia repair (VHR) have limited external validation. Our aim was to determine (1) whether existing models stratify patients into groups by risk and (2) which model best predicts the rate of SSO a...
[ "Hypocalcemia and nerve injury are the most severe complications after thyroid surgery. The duration of surgery has not been previously considered as a risk factor for postoperative complications in patients undergoing total thyroidectomy. We sort to investigate the influence of prolonged surgery on postoperative c...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Can EMS Providers Provide Appropriate Tidal Volumes in a Simulated Adult-sized Patient with a Pediatric-sized Bag-Valve-Mask?
[ "In the prehospital setting, Emergency Medical Services (EMS) professionals rely on providing positive pressure ventilation with a bag-valve-mask (BVM). Multiple emergency medicine and critical care studies have shown that lung-protective ventilation protocols reduce morbidity and mortality. Our primary objective w...
[ "Congenital and acquired upper airway obstruction in infants commonly manifests as an acute, potentially life-threatening condition or a slow and gradual deterioration and can be a challenge to the pediatric anesthesiologist. This case series reports the nonconventional use of pediatric airway exchange catheters em...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Can students' scores on preclerkship clinical performance examinations predict that they will fail a senior clinical performance examination?
[ "This study was designed to determine whether preclerkship performance examinations could accurately identify medical students at risk for failing a senior clinical performance examination (CPE). This study used a retrospective case-control, multiyear design, with contingency table analyses, to examine the performa...
[ "Changes in the spectrum of general surgery and the delivery of surgical care have placed the requirement for a mandatory general surgery rotation in the surgical clerkship in question. We tested the hypothesis that equal mastery of surgical clerkship objectives can be obtained in a clerkship with and without gener...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Recovery Outcome Measures: Is There a Place for Culture, Attitudes, and Faith?
[ "Utilization of the Recovery Knowledge Inventory (RKI) and Recovery Attitudes Questionnaire (RAQ) in southeastern Australia raised questions about the RAQ, including links between attitudes, faith, and culture in supporting the recovery journey. These questions are particularly important when considered in the cont...
[ "Parents often accompany adolescent and young adult (AYA) pediatric cancer survivors to follow-up oncology clinic visits and remain involved in their care, although little is known about their reasons for doing so. This mixed methods (qualitative-quantitative) study of 76 mothers of AYA survivors of childhood cance...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Can surgeon familiarization with current evidence lead to a change in practice?
[ "Despite evidence against its utility, many surgeons continue to employ prophylactic nasogastric decompression in elective colonic resection. This study aimed to establish whether an easy and practical intervention, mailing out a summary of current evidence to surgeons, can change surgeons practice to bring it more...
[ "Practice pattern data demonstrate regional variation and lower than expected rates of adherence to practice guideline (PG) recommendations for the treatment of stage II/IIIA resected and stage IIIA/IIIB unresected non-small cell lung cancer (NSCLC) patients in Ontario, Canada. This study sought to understand how c...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Advanced epithelial ovarian carcinoma in Thai women: should we continue to offer second-look laparotomy?
[ "To determine survival among patients with epithelial ovarian carcinoma (EOC) who underwent a second-look laparotomy (SLL) and those refusing the procedure. Also to analyze factor(s) influencing the survival of the patients. Medical records were reviewed of patients with advanced EOC who were clinically free of dis...
[ "Prognosis in ovarian cancer is determined by completeness of cytoreduction and proper management by specialized oncological gynecologists. Incomplete initial debulking surgery in non-specialized Centers is, however, a reality and there is ongoing discussion about the best subsequent management of such patients. Pa...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is high-sensitivity C-reactive protein associated with carotid atherosclerosis in healthy Koreans?
[ "There is a positive association between chronic inflammation and the risk of cardiovascular disease, but whether there is an association between C-reactive protein (CRP) and carotid atherosclerosis is controversial. We investigated the relationship between high-sensitivity CRP (hsCRP) levels and carotid intima-med...
[ "Endothelial dysfunction is one of the most important early indicators of atherosclerosis in hypertension (HT) patients. Endocan has been reported to play a role in the pathophysiology of endothelial dysfunction. We sought to assess whether serum endocan levels are correlated with the presence and severity of coron...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Validation of the 2009 TNM version in a large multi-institutional cohort of patients treated for renal cell carcinoma: are further improvements needed?
[ "A new edition of the TNM was recently released that includes modifications for the staging system of kidney cancers. Specifically, T2 cancers were subclassified into T2a and T2b (<or =10 cm vs>10 cm), tumors with renal vein involvement or perinephric fat involvement were classified as T3a cancers, and those with a...
[ "Upper tract urothelial carcinoma (UTUC) is a clinically heterogeneous disease that lacks high-quality trials that provide definitive prognostic markers. Insulin-like growth factor messenger RNA binding protein 3 (IMP3) has been associated with outcomes in urothelial carcinoma of the bladder but was not yet studied...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?
[ "To describe the interstitial fluid (ISF) and plasma pharmacokinetics of meropenem in patients on continuous venovenous haemodiafiltration (CVVHDF). This was a prospective observational pharmacokinetic study. Meropenem (500 mg) was administered every 8 h. CVVHDF was targeted as a 2-3 L/h exchange using a polyacrylo...
[ "Therapeutic failure of antibiotic therapy has been ascribed to pharmacokinetic alterations in compromised patient populations. The present study, therefore, aimed at examining the influences of cardiac surgery and intensive care procedures on the postoperative target site distribution of piperacillin. For this pur...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does Sensation Return to the Nasal Tip After Microfat Grafting?
[ "Patients usually complain about numbness in the nasal tip after microfat injections. The present study evaluated the severity of the numbness in the nasal tip after the procedure. To address the research question, a prospective study of young women was designed and performed at the Beijing Anzhen Hospital. Time wa...
[ "To discuss the elements of interdisciplinary research and to analyze its contribution to (bio)medical informatics. Commenting on 'Informatics and Medicine - From Molecules to Populations' from K. A. Kuhn et al. in this issue of Methods of Information in Medicine. Referring to examples of successfully established i...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Do older men benefit from curative therapy of localized prostate cancer?
[ "Prior decision-analytic models are based on outdated or suboptimal efficacy, patient preference, and comorbidity data. We estimated life expectancy (LE) and quality-adjusted life expectancy (QALE) associated with available treatments for localized prostate cancer in men aged>/= 65 years, adjusting for Gleason scor...
[ "Study Type - Prognosis (cohort series). Level of Evidence 2a. What's known on the subject? and What does the study add? The incidence and prevalence of obesity in the USA and Europe is increasing. Higher body mass index is associated with a lower risk of overall prostate cancer diagnosis but also with an increased...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Pituitary apoplexy: do histological features influence the clinical presentation and outcome?
[ "A retrospective analysis of a contemporary series of patients with pituitary apoplexy was performed to ascertain whether the histopathological features influence the clinical presentation or the outcome. A retrospective analysis was performed in 59 patients treated for pituitary apoplexy at the University of Virgi...
[ "An elevated body mass index (BMI) is suggested to be a risk factor for a poor outcome after intracranial aneurysm rupture and is considered to be associated with cerebral infarction in patients with aneurysmal subarachnoid hemorrhage (SAH). The aim of this study was to analyze the association between permorbid BMI...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Do African American women require fewer calories to maintain weight?
[ "The high prevalence of obesity in African American (AA) women may result, in part, from a lower resting metabolic rate (RMR) than non-AA women. If true, AA women should require fewer calories than non-AA women to maintain weight. Our objective was to determine in the setting of a controlled feeding study, if AA wo...
[ "What are the lifestyle choices and dietary aspects of women about to undergo fertility treatment in New Zealand?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Emergency double-balloon enteroscopy combined with real-time viewing of capsule endoscopy: a feasible combined approach in acute overt-obscure gastrointestinal bleeding?
[ "There are few data concerning emergency double-balloon enteroscopy (DBE) and its usefulness in the management of severe acute obscure gastrointestinal bleeding (OGIB). The aim of this retrospective study was to evaluate emergency DBE and capsule endoscopy (CE) in patients with overt OGIB, analyzing the feasibility...
[ "It has recently been reported that in developed countries gastric outlet obstruction now predicts gastric malignancy. The aim of this study was to find out if this is the case in a developing country like India. Seventy-four patients with gastric outlet obstruction underwent upper gastrointestinal endoscopy and bi...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }