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pmc-6142765-1
An 81-year-old Caucasian woman was referred to our department for several weeks of symptoms such as chills, fever, malaise, fatigue, and recurrent tumble despite antibiotic therapy. She was treated prior to admission for approximately two weeks with antibiotics in another hospital. The patient had an important abdomina...
pmc-6143088-1
A 37-year-old gravida 2 para 1 (one previous c-section for breech position with a daughter of 3300 g) presented at 19 weeks due to an increased alfafetoprotein on an integrated biochemical screening test (AFP: 3.5 MoM). Ultrasound revealed normal fetal growth, no structural anomalies, normal dopplers. Placental lakes (...
pmc-6143159-1
A 62-year-old man presented to our ambulatory clinic with an elevated prostate-specific antigen (PSA) of 7.7 ng/mL. The digital rectal examination revealed no changes. Transrectal biopsies were performed, revealing prostate cancer Gleason 6 (3 + 3) on the right side (apex). He was subjected to a transperitoneal laparos...
pmc-6143322-1
A 9-year-old female presented with progressive, PG-like lesions involving her left arm following a minor abrasive trauma in a playground accident (Fig. A). She had been previously diagnosed with LAD-1 at 18 months of age. Her CD18 expression level was 5–10%, or mild/moderate phenotype. She had never experienced life-th...
pmc-6143370-1
A 32-year-old woman (59 kg, 1.68 m) with a five-year history of generalized tonic-clonic seizures presented to Inova Loudoun Hospital's emergency room on June 6, 2016. Upon presentation, the patient suffered a generalized tonic-clonic seizure that lasted for more than one minute. She recently immigrated from Honduras, ...
pmc-6143371-1
Case 1: A 49-year-old woman presented to the dermatologist for routine skin screening. Her past medical history was significant for fibromyalgia, hyperlipidemia, hypertension, and obstructive sleep apnea. She had also a history of actinic keratosis, basal cell carcinoma, and melanoma. Cutaneous examination showed dark ...
pmc-6143371-2
Case 2: A 58-year-old woman came in for evaluation of a lesion on her right thigh that had enlarged. She had a past medical history of arthritis. A cutaneous exam showed an ulcerated nodule on her right thigh. Biopsy showed benign prurigo nodularis. Examination of her nails showed a split in the lateral portion of her ...
pmc-6143371-3
Case 3: A 64-year-old man came in for evaluation of a lesion on his left upper lip. His past medical history included gastroesophageal reflux disease, hyperlipidemia, and obstructive sleep apnea. Skin history included a prior basal cell carcinoma. Cutaneous examination revealed a plaque on his upper lip; a biopsy of th...
pmc-6143664-1
MT is a 43-year-old right-handed woman who used to work as a lawyer. At the age of 42 years, she had suffered a rupture of the cerebellar arteriovenous malformation (AVM), which was treated with embolization (July 2014). Ten months after the lesion (May 2015), she was admitted to the Ataxia Laboratory of IRCCS Fondazio...
pmc-6144491-1
A male infant, who was term appropriate for gestational age, was born via repeat caesarean section to a healthy 26-year-old woman. No family history of bleeding disorders was reported by the mother. Pregnancy was unremarkable, and Apgar scores were 9 and 9 at 1 and 5 minutes, respectively. On initial physical examinati...
pmc-6144491-2
A term male infant weighing 3885 g (>95th percentile) was born vaginally to a 22-year-old woman. No family history of bleeding disorders was reported by the mother. The pregnancy was uneventful and resuscitation was uncomplicated. The initial physical examination in the newborn nursery was unremarkable; however, at 6 h...
pmc-6144491-3
A large-for-gestational-age, term male infant was born via spontaneous vaginal delivery to a 34-year-old woman. Pregnancy was complicated by little to no prenatal care. Maternal serologies were unknown. The labor was prolonged with rupture of membranes 29 hours before delivery. The infant required oxygen and brief bag ...
pmc-6145046-1
A 59-year-old male was diagnosed with AATD in 1997 by AAT immunoassay (level) and began augmentation therapy in 2014. In 2015, Pi phenotyping yielded Pi MZ results and AAT level of 72mg/dL (13.8 uM). He was identified as a MZ heterozygote and informed his family members of MZ-associated familial risk. Two siblings had ...
pmc-6145046-2
An 18-year-old male was referred to pulmonology with documented MZ status and AAT level of 64 mg/dL (12.3 uM). The participant's father died of ZZ-AATD disease. He had targeted familial genotyping, which identified a single Z allele as expected, and received consultation about MZ health and reproductive risks. The SZ r...
pmc-6145046-3
A 58-year-old female tested through the ACT study in 2014 due to pulmonary symptoms. Prior to 2015 the ACT study performed targeted genotyping for the S and Z mutations only and estimated AAT level. She received a MZ result with AAT level 78 mg/dL (15 uM). The F allele is a dysfunctional allele where the functional cap...
pmc-6145046-4
A 57-year-old male tested through the ACT study in 2016 after his brother was diagnosed with AATD-emphysema. He did not know his brother's genotype. ACT results reported the MZ genotype and level of 70.1 mg/dL (13.6 uM). NGS identified the Smunich variant (c.1061C>T, p.Ser330Phe) which was classified by Biocerna LLC as...
pmc-6145046-5
A 34-year-old male tested through the ACT study in 2011 and received results with the MZ genotype and level of 80.6 mg/dL (15.5 uM). NGS identified the M2obernburg variant (c.710T>C, p.Gly148Trp) which was classified by Biocerna LLC as a variant of uncertain pathogenicity and uncertain clinical significance [, ]. Inter...
pmc-6145046-6
A 65-year-old female tested through the ACT study in 2013 and received results with the MZ genotype and level of 77.0 mg/dL (14.8 uM). NGS identified the c.922G>T (p.Ala308Ser) which was classified by Biocerna LLC as a variant of unknown clinical significance []. Interpretation of this result in the context of AAT leve...
pmc-6145057-1
A 93-year-old Caucasian female was brought to emergency room for gradual decline in mental status over a course of one week. Her past medical history was significant for coronary artery disease, hypertension, diabetes mellitus, hyperlipidemia, and mild cognitive dysfunction. Her medications included aspirin 81 mg daily...
pmc-6145100-1
MECM, a 49-years-old previously healthy woman, married and childless, was admitted at a private hospital in Natal City, Rio Grande do Norte State, Brazil, in June, 2014 for a microsurgery of neuroma. She used to live in a flat with a parrot who had an unknown disease that caused loss of feathers. The microsurgery was p...
pmc-6145115-1
A 56 year old Sri Lankan female presented with fever, chills and rigors for 2 weeks. She was diabetic and her glycaemic control was fairly good with oral hypoglycaemic drugs: fasting blood sugar was 112 mg/dl and HbA1C was 5.7%. At presentation, fever was associated with constitutional symptoms like malaise and loss of...
pmc-6145116-1
A 12-year-old Saudi boy of Arab ethnicity, with no past relevant medical, surgical, family, or psychosocial history, presented to the King Saud Medical City emergency department with bleeding per rectum and mild abdominal pain 3 days after blunt abdominal trauma while playing football. On examination, his abdomen was s...
pmc-6145152-1
A 49-year-old female presented with a 2-month history of asymptomatic lesions on the left knee found incidentally on routine full skin examination. The patient was otherwise well, with no pulmonary or systemic symptoms. She had a past history of breast cancer diagnosed 4 years ago, managed by lumpectomy and adjuvant ch...
pmc-6145163-1
In 1978, a 41-year-old woman was diagnosed as a hemophilia carrier with a low FVIII level; from the age of 13, she had suffered menorrhagia of up to 8 days each month. In addition, she had suffered five episodes of hematemesis associated with epigastric pain and abundant hemorrhages during the births of her two sons an...
pmc-6145202-1
A 20-year-old man with no medical history was referred to the Ear, Nose, and Throat (ENT) emergency room at Shenzhen People’s Hospital on June 17, 2008. He had an extended laceration of his left ear by a shattered beer bottle during a violent fight 3 h ago. On examination, the external auditory canal of his left ear wa...
pmc-6145316-1
A 22-year-old patient, Para 1, Gravida 2, presented to our Emergency Department of Gynecology and Obstetrics, at 35 weeks of gestation for acute onset of abdominal pain and uterine contraction. It was learned that the patient's history had no follow-up hypertriglyceridemia. On physical exam, her heart rate was at 100 p...
pmc-6145538-1
A 70-year-old man presented in 2017 after discovery of a hypervascular, expansile, 7 cm pancreatic body mass involving the splenic vein on routine surveillance CT scan (). He endorsed 1 year of diarrhea and steatorrhea that he had not sought medical care for but denied weight loss, appetite changes, fatigue, pain, or j...
pmc-6145540-1
A 42-year-old man presented to our pancreas multidisciplinary clinic after a computed tomography (CT) scan (), prompted by a 2-month history of generalized bloating and epigastric discomfort, that demonstrated a 11.2 × 9.6 cm heterogeneous solid appearing mass in the tail of the pancreas. The irregular mass had several...
pmc-6145751-1
A 45-year-old, Caucasian male patient presented with right knee pain that started a year ago and aggravated eight months ago. He was an English teacher and denied a history of any trauma. The symptom sustained despite six months of conservative treatment at another clinic, including intermittent non-steroid anti-inflam...
pmc-6145752-1
A 78-year-old male presented to the emergency room with complains of high fever, and non-bloody non-bilious vomiting. This was associated with a non-productive cough and dyspnea. He had a past medical history of splenectomy following thrombotic thrombocytopenic purpura (TTP) and recurrent pneumonia. On presentation, th...
pmc-6145755-1
A 19-year-old boy was admitted with a history of recurrent bouts of epistaxis from his right nostril, for a duration of one month. The last episode was severe and uncontrolled, which prompted him to seek medical attention. His past medical history involved a motor vehicle accident four months prior to admission. This e...
pmc-6145800-1
A 47-year-old Caucasian male presented to the emergency department (ED) for diffuse erythema and pruritus of three weeks’ duration. The patient had been followed in dermatology clinic for hand-foot dyshidrotic eczema for approximately three years prior to his admission. The patient’s eczema had been well controlled on ...
pmc-6145801-1
A 33-year-old male presented to be admitted as a patient at Case Western Reserve University School of Dental Medicine clinic in Cleveland, Ohio for the purpose of obtaining dental implants. However, the patient complained of pain in his upper jaw bilaterally. His medical history was free from systemic diseases but indi...
pmc-6146110-1
A 52-year-old woman noticed a right breast mass and underwent a breast examination at a local breast clinic, after which she was referred to our hospital for a further investigation. The patient’s medical history included early gastric cancer and early esophageal cancer, and her family history included breast cancer in...
pmc-6146113-1
A 10-day-old male infant was referred to our hospital because of suspected congenital hypothyroidism. The patient presented with symptoms of airway obstruction, such as an inspiratory stridor and retracted breathing. A hormonal test revealed subclinical hypothyroidism with a free thyroxine level (1.44 ng/dL) within the...
pmc-6146114-1
A 57-year-old Japanese man was referred to our hospital because of increasing right lower abdominal pain. He had a history of appendectomy at the age of 17 years with no significant family or occupational history. On initial examination, an abdominal wall tumor (largest dimension, approximately 10 cm in diameter) was d...
pmc-6146370-1
A 16-year-old boy with a family history of seizures (mother, cousin) exhibited typical development until the age of 14; this was the point at which he developed generalized epilepsy, which was well-controlled using valproic acid (VPA). He also had a family history of high blood lactate levels (mother) and a history of ...
pmc-6146567-1
An 89-year-old man with a history of Fuchs corneal endothelial dystrophy presented in the left eye with reduced visual acuity and discomfort due to the development of pseudophakic corneal edema following previous uneventful cataract surgery in 2005. The best spectacle corrected distance visual acuity (BSCVA) was 6/18 (...
pmc-6146617-1
A 52-year-old man presented with intermittent, two-month-duration painless gross hematuria without clot formation and was referred to the Urology Department for evaluation of urologic malignancy. He had multiple bruises and a history of nasal bleeding during childhood. Low platelet levels (34000-38000/μL) and high lact...
pmc-6146624-1
A 62-year-old woman with HBV-related hepatopathy has been suffering for a few months of pain and a sense of weight in the right hypochondriac site. A CT scan reveals a lesion of about 5 cm between the VI hepatic segment and right colon. Colonoscopy demonstrates near the right colonic flexure an ab extrinseco compressio...
pmc-6146629-1
A seven-and-a-half-year-old male child was sent to our Pediatric Endocrinology Centre for macrocephaly and right lateralized overgrowth, reported from birth. Parents were not related and no noteworthy diseases were reported in his family history. The pregnancy was characterized by spontaneous abortion of the dizygotic ...
pmc-6146633-1
A 50-year-old Caucasian man with a remote history of deep venous thrombosis (DVT) at the lower extremities presented with abdominal pain. His medications included acetylsalicylic acid. Physical examination revealed abdominal tenderness and a palpable mass at the left abdominal area. Laboratory exams revealed a normocyt...
pmc-6146636-1
A 54-year-old Asian American woman presented to her family physician with right side flank pain. She had no other symptoms, and her physical exam was normal. Laboratory testing showed elevated liver function tests including alkaline phosphatase and aspartate aminotransferase. An abdominal ultrasound showed a 1.5 cm hyp...
pmc-6146661-1
A 38-year-old man with past history of hypertension was admitted for a lumbosacral spine surgery. He had been taking Valsartan 160 mg a day for the past 4 years. He underwent two uneventful previous surgeries before diagnosis of hypertension and was not known to have prior drug intolerance or atopy with unremarkable fa...
pmc-6146670-1
A 78-year-old man presented with a slowly growing, painless, immobile right hemiscrotal mass over a nine-month period. An ultrasound study revealed a large right inguinal hernia containing herniated intra-abdominal fat (Figures and ). On surgical exploration, the mass was encasing the right testicle requiring radical o...
pmc-6146670-2
A 49-year-old man presented with a painless, nontender, nonreducible, firm, immobile, slowly enlarging right hemiscrotal mass over a one-year period. CT imaging revealed a right inguinal hernia with intraperitoneal fat extending inferiorly into the scrotal sac (Figures –). Subsequently, a 14 × 10.5 cm membranous sac wa...
pmc-6146672-1
A 40-year-old male presented with complaints of instability and defect in his left knee since 6 months. The patient gave a history of trauma 6 months back and did not take any treatment for this. Clinically, anterior defect was present over the left knee with visibility of intercondylar articulating surfaces of the tib...
pmc-6146677-1
This is a fifty-five-year-old woman with past appendectomy. She was perimenopausal and had no treatment. Her brother had a rectum neoplasia. She had four children. She suffered from anemia because she had menorrhagia since few months. Ultrasonography examination revealed a polymyomatous uterus and a vascularized polyp ...
pmc-6146767-1
The first case shows a 30 year old female. Clinical and radiographic examination showed a skeletal Class II pattern with an anterior open bite and a transverse maxillary deficiency with a lateral posterior crossbite on the right and the tendency to a lateral crossbite on the left (Fig. ). The treatment plan involved a ...
pmc-6146767-2
The second case shows a 53-year-old female. Clinical and radiographic examination confirmed a unilateral posterior crossbite due a transverse maxillary deficiency with a significant mandibular skeletal deviation towards the side of the crossbite (Fig. ). Treatment objectives. SARME was planned to correct the transverse...
pmc-6146767-3
The third case shows a 30-year-old male. Clinical and radiographic examination confirmed a concave profile, a skeletal Class III pattern with a complete anterior and posterior crossbite. Transverse deficiency of the maxilla was evident with compensatory labial tipping of the upper incisors (Fig. ). Firstly SARME was pl...
pmc-6146902-1
A 20-year-old female patient was admitted to the Department of Restorative Dentistry, Faculty of Dental Medicine, Kırıkkale University, with aesthetic concerns. The anamnesis did not specify any systemic illnesses of the patient. After the clinical and radiographic examinations, hypomineralization was identified in the...
pmc-6147009-1
We present a case of a female aged 33 with a diagnosis of NFI. She presented with a longstanding history of bilateral nipple skin tags. No family history of NFI was documented. She had a history of hypothyroidism, epilepsy, and learning difficulties. On clinical examination, bilateral, pedunculated, polypoid, and flesh...
pmc-6147040-1
The patient was a 64-year-old man, who had bilateral ptosis, diplopia and exercise intolerance. His early development had been normal and currently he had no regular medication. Ocular symptoms had started to develop at the age of 54 years, the right eye had been operated due to squint at the age of 58 years and ptosis...
pmc-6147263-1
In November 2008, a 61-year-old man was admitted to the Ear, Nose and Throat (ENT) and Cervico- facial Surgical Department of Salah Azaez Oncology Institute for the treatment of T2N0M0 squamous cell carcinoma of the right hemi larynx. The patient was a heavy smoker, a consumer of alcohol and had a long history of dysph...
pmc-6147265-1
A 52-year-old male patient presented with a history of a change in the voice over 3 months, with neither sore throat nor fever. Physical examination revealed right-sided grade IV and left-sided grade III tonsillar enlargement with prominent vessels (). Serology was negative for human immunodeficiency virus (HIV), and o...
pmc-6147267-1
A 21-year-old male student presented to the emergency department with severe headache for 15 days, periorbital swelling, pain and double vision in the right eye for 10 days, fever for 7 days and left lower limb weakness for 5 days (). His past history was unremarkable, and no significant family history was found. The p...
pmc-6147272-1
A 30-year-old woman was referred to our clinic with a 2-month history of epistaxis and necrotizing lesions of her nose with a background of chronic sinusitis and rhinorrhea. Ear, nose, and throat (ENT) examination of the patient indicated a defect in her nasal septum. The coronal and axial cut of computed tomography (C...
pmc-6148720-1
A 54-year-old Chinese woman with a 5-year history of multiple nodules under the subcutaneous tissues on the right auricle () was referred to their hospital in April 2009. The patient also suffered from itching and occasional tingling in the right auricle. Topical corticosteroids and oral antihistamines were prescribed,...
pmc-6148735-1
A 9-month-old baby girl from the Adamawa Region of Cameroon was brought to the out-patient department of our hospital by her mother for a reddish, “snake-like” rash on the child’s abdomen that appeared 3 days prior to consultation. The mother suspected the lesions were pruritic because her child was irritable and seeme...
pmc-6148795-1
The patient is a 16-year-old boy, born at term by natural delivery from unrelated healthy parents. The mother and father were 38 and 43 years old at time of birth. Prenatal NT at ultrasound examination and karyotype on amniocytes, performed because of advanced maternal age, were referred as normal. Patient birth weight...
pmc-6148997-1
A 55-year-old woman was referred to the Peking Union Medical College Hospital in September 2015 for rectorrhagia and intermittent abdominal pain lasting 6 months. The patient had a past medical history of ovarian endometriosis and had undergone excision of bilateral ovarian chocolate cysts in 1988 when she was 30 years...
pmc-6149011-1
A male patient, 26 years old, sought care at the dental clinic with fractures of the left maxillary central incisor resulting from a sudden strike three months earlier. The patient had no clinical symptoms during this period (Fig. ). A clinical examination revealed that the left maxillary central incisor was fractured ...
pmc-6149011-2
A 61-year-old female patient was referred to the clinic with dental caries of her left maxillary central incisor. The patient had no clinical symptoms (Fig. ). A clinical examination revealed that the left maxillary central incisor had caries in the middle third of the crown, which involved the enamel and dentin with n...
pmc-6149070-1
A 49-year-old, previously healthy, Caucasian man, a motorcyclist, was referred to our Emergency Department (ED) after a high velocity frontal collision with a car. He was married and worked as a car body repairer. He had no tobacco smoking or drinking history and was not taking any medication. A prehospital primary sur...
pmc-6149227-1
The pedigree of the family is shown in Fig. . The proband (Ib in Fig. ) was a 47-year-old female of Han Chinese ethnicity (with family from Shandong province, China), who was admitted to our hospital with a chief complaint of “fatigue and chest tightness for 7 days”. She never had a similar episode before. She had neit...
pmc-6149836-1
A 42-year-old Caucasian female with pseudoxanthoma elasticum, who had been diagnosed with bilateral AS and CNV secondary to AS in the left eye (OS), was treated with 12 intravitreal injections (IVIs) of ranibizumab (0.5 mg [50 µL]) over a period of 13 months. Despite the intensive treatment with ranibizumab, no signifi...
pmc-6150707-1
Female patient aged 11 years and 2 months, previously diagnosed with agenesis of tooth #32, was referred by the pediatric dentist for orthodontic evaluation. The patient reported dissatisfaction with “misaligned lower teeth and very narrow smile” (). The medical and dental histories were uneventful, and anamnesis revea...
pmc-6150744-1
A 68-year-old male presented to the emergency department with left-sided abdominal pain, early satiety, fatigue and 7 lbs weight loss for seven weeks. His past medical history was significant for hypertension, emphysema and HCV with an undetectable HCV ribonucleic acid (RNA) following treatment with sofosbuvir and riba...
pmc-6150745-1
The patient is a 73-year-old male, with only a past medical history of bilateral cataracts and hyperlipidemia. He had complained of one year of left-sided radiating neck pain into the shoulder, arm and the second digit, with numbness in the second digit. He was noted to have a palpable left anteromedial upper arm mass ...
pmc-6150749-1
A 36-year-old female with past medical history significant for schizophrenia presented to the hospital after experiencing arthralgia for nine days followed by an evanescent rash for three days accompanied by persistent high-grade fever. Her symptoms were associated with pleuritic chest pain. The rash was non-pruritic a...
pmc-6150750-1
The patient is a 46-year-old right-handed female with a past medical history of hypertension (HTN), hyperlipidemia (HLD), diabetes mellitus type two (DM2), obesity, and hemorrhagic stroke who was transferred from an outside facility to be evaluated for CNS vasculitis. She was admitted to this outside facility for a fou...
pmc-6150751-1
A 30-year-old male with no past medical history moved from Puerto Rico three weeks prior to admission. He was found unresponsive at home with foamy secretions around his mouth. Paramedics found him apneic and pulseless. Cardiopulmonary resuscitation (CPR) was initiated and he had the return of spontaneous circulation a...
pmc-6150752-1
A 79-year-old African American male was admitted for evaluation of two episodes of melena within one day. No associated abdominal pain, nausea, weight loss, appetite changes, diarrhea, hematemesis, or hematochezia was reported. His past medical history was significant for chronic obstructive pulmonary disease (COPD), h...
pmc-6150755-1
A 47-year-old female with an active substance use disorder involving intravenous (IV) heroin, amphetamines, benzodiazepines, and a known history of asthma and chronic obstructive pulmonary disease (COPD) was found cyanotic at home in a prone position. She was hypoxemic on room air with oxygen saturation of 50% but emer...
pmc-6150760-1
A 26-year-old male patient with a past medical history of asthma and marijuana use presented to the emergency room with a one-week history of shortness of breath. The patient believed his shortness of breath was associated with his asthma and he did not seek help earlier. The patient reported having exertional dyspnea,...
pmc-6150762-1
A 24-year-old male presented with severe throbbing pain extending from the distal half of his left thigh to his left foot. The pain initially began four years prior, was mild, and was triggered by walking one-half to one mile. The pain progressed and is now triggered by walking one block and relieved by several minutes...
pmc-6150764-1
A 70-year-old male, known case of diabetes mellitus, hypertension and coronary artery disease, presented with complaints of increased appetite, weight loss, palpitations and heat intolerance. Physical examination revealed 4 cm thyroid nodule in the left lobe on palpation. His blood pressure was 130/85 mmHg, and resting...
pmc-6150765-1
A 24-year-old female patient presented to the otolaryngology clinic with a six-month history of progressive hoarseness of voice. In addition, she has a recent history of mild dyspnea on exertion and dry cough. The patient did not have any weight loss nor dysphagia. The patient was a cigarette smoker of around one pack ...
pmc-6150766-1
A 60-year-old Caucasian male known to have a bicuspid aortic valve was admitted with a three-day history of cough, altered mental status, and left upper extremity weakness. He did not have any other significant medical or surgical history. At presentation, he was confused and afebrile. His Glasgow Coma Scale (GCS) scor...
pmc-6150767-1
A 70-year-old African American male was seen in the emergency department for acute anxiety and paranoia. He reported that his son gave him melatonin to help him sleep, but he felt the medication was poisonous. He also reported that he was struggling with the death of his partner of 40 years and was feeling anxious. The...
pmc-6150771-1
A 60-year-old male patient presented to the dermatology outpatient department (OPD) with a two-month history of diffuse facial erythema, itching, and burning sensation. Raised skin lesions were noted on the forehead, nose, and left cheek. He also complained about the exacerbation of lesions upon exposure to the sun. On...
pmc-6150772-1
A 40-year-old man with a history of end-stage renal disease on hemodialysis, hypertensive cardiomyopathy, and poorly controlled hypertension presented to the emergency department with a sudden onset of 48-hour right visual blurring and headache. On physical examination, he was alert, oriented to time, place and person,...
pmc-6150885-1
A 38-year-old gravida 1 para 0010 female presented with infertility of 15 years duration. The patient was initially referred 9 years earlier by her gynecologist and underwent a laparoscopy and hysteroscopy with findings of stage I endometriosis, patent right fallopian tube, and intrauterine synechia. The patient’s obst...
pmc-6150971-1
A 33-year-old female nonsmoker with a 4-month history of intermittent chest pain and dyspnea at rest, which recurred every 2 weeks, was admitted to our hospital at 31 weeks of gestation. Four months ago, she had been admitted after experiencing these symptoms for the first time. A chest radiograph at that time revealed...
pmc-6151028-1
The second case was a 41-years-old female with a WHO°II diffuse Astrocytoma (IDHmt, no LOH 1p19q, mMGMT) that underwent gross total resection (GTR) and also was in an excellent physical status (KPS 90%). This case represents a high-risk Astrocytoma situation based on the inclusion criteria of the RTOG 9802 trial [].
pmc-6151028-2
The third case was a 31-year-old female with a WHO°II diffuse Astrocytoma without IDH1 mutation, without LOH 1p19q, and without MGMT promoter hypermethylation. The patient underwent GTR and was in an acceptable physical Status (KPS 80%), yet there was some minor hemiparesis present after surgery. According to the RTOG ...
pmc-6151035-1
The authors report two Moroccan cases of dermoscopy in skin metastasis of breast cancer with two different clinical presentations; the dermoscopic examination was performed using a Dermatoscope Delta® 20 (Heine; Herrsching, Germany) with polarized light and without immersion. Case 1 was a 51-year-old Moroccan woman dia...
pmc-6151044-1
A 21-year-old man complained of transient muscle stiffness since 10 years. He experienced difficulty in initiating movement and felt muscle weakness after rest. However the symptoms typically improved after repeated contraction (warm-up phenomenon). The symptoms tended to aggravate during cold weather. He was unable to...
pmc-6151052-1
A 3-year-old boy presented to our hospital with a 3-month history of foamy urine. He was born at gestational age of 36 weeks 6 days to a young couple with no history of consanguinity. Prior history was significant for decreased amniotic fluid volume, which was detected since gestational age of 5 months. According to th...
pmc-6151189-1
A 48-year-old Caucasian man was admitted to our emergency ward. His medical history included an episode of depression and some disabilities in reading and writing. From the age of 1 to 8 years, he had recurrent episodes of seizures associated with vomiting and loss of unconsciousness, which had been interpreted as febr...
pmc-6151194-1
A 52-year-old postmenopausal female of Filipino origin presented to hospital with a three-day history of increasing abdominal bloating, vomiting, and fevers. She denied urinary or bowel symptoms. This patient had no significant past medical or family history and was a nonsmoker. She moved to Australia from the Philippi...
pmc-6151198-1
A 31-year-old African American female was found to have severe anemia on laboratory work performed by her gynecologist. The patient reported fatigue and dyspnea on exertion for about two months. She also had a two-week history of gum bleeding while brushing her teeth. She denied any other bleeding, weight loss, chills,...
pmc-6151199-1
A 73-year-old Caucasian male presented with three weeks of dyspnea, headache, and lower extremity edema. Initial labs were significant for marked leukocytosis with increase in myeloid precursors and rare blasts: white blood cell (WBC) 156 k/μL, neutrophils 103 k/μL, monocytes 7.1 k/μL, eosinophils 1.6 k/μL, basophils 0...
pmc-6151203-1
A 58-year-old female was found unresponsive after a house fire, with the primary cause of death anoxic brain injury. Despite a short period of asystole, her renal function was preserved with an admission creatinine of 0.88, peak creatinine of 1.24, and a final creatinine of 1.04. The Kidney Donor Profile Index (KDPI) w...
pmc-6151203-2
A 57-year-old male found unresponsive after a house fire subsequently developed pulseless electrical activity (PEA) arrest with the primary cause of death documented as anoxic brain injury. The donor met criteria to be considered public health services (PHS) high risk given his recent history of incarceration. Overall,...
pmc-6151209-1
A 73-year-old woman presented with the complaint of left ankle pain that had exacerbated with walking for the previous month. She had a limping gait and complained of a limited walking ability of 5–10 minutes with a cane because of pain. She originally had limited walking ability due to a cerebral infarction 10 years p...
pmc-6151219-1
A 44-year-old woman was diagnosed with iron deficiency anemia but showed no abnormalities on gastrointestinal tract endoscopy 5 years prior to the current presentation. A blood test for health screening showed anemia with hemoglobin 7.6 g/dL, and uterine fibroids were suspected on abdominal ultrasonography. She was dia...
pmc-6151220-1
This patient, a 63-year old male, was referred with MDS by an indication of MDS with excess blasts. Chromosomal analysis showed a karyotype of 46,XY,der(15)t(1;15)(q12;p11.2)[4]/46,XY,der(22)t(1;22)(q12;p11.2)[2]/46,XY[7]. FISH analysis using dual color probes for the CDKN2C gene at 1p32.3 and CKS1B gene at 1q21.3 conf...
pmc-6151222-1
A previously healthy 35-year-old African American male presented with a one-month history of worsening lower back and bilateral lower extremity pain, intermittent night sweats, and 32 kg unintentional weight loss over the course of a year. He did not have saddle anesthesia or urinary or fecal incontinence. He was initi...