id stringlengths 36 36 | input stringlengths 26 249 | expected_output stringlengths 29 160 | metadata.query_id stringlengths 1 4 | metadata.split stringclasses 1 value |
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070f02c4-4357-4e32-a3d7-6bc0abb9be86 | siRNA knockdown of A20 accelerates tumor progression in an in vivo murine xenograft model. | [{"id": "33370", "score": 1}, {"id": "38355793", "score": 1}] | 1403 | train |
12e060e1-2cb5-4c02-8926-229cb7034023 | Long chain polyunsaturated fatty acids supplementation reduces wheezing and asthma. | [{"id": "22442133", "score": 1}] | 710 | train |
25b014d6-1f22-43db-bf28-efe2c347ab2a | In transgenic mice harboring green florescent protein under the control of the Sox2 promoter, more than 50 percent of the cells with green florescent colocalize with cell proliferation markers. | [{"id": "16999023", "score": 1}] | 588 | train |
65a47e2d-8890-486c-a19f-c5ab9ae2e601 | r-protein chaperones are found in complexes with their r-protein binding partners. | [{"id": "8126244", "score": 1}] | 1402 | train |
89799cb8-0c55-4d7d-a7ff-64902b1eb1ed | Chlamydia trachomatis is most prevalent in the UK among sexually-experienced individuals aged 16 to 24. | [{"id": "5850219", "score": 1}] | 256 | train |
70773f4a-901a-4b62-b08b-35e81edeb522 | Foxp3 represses the expression of transcriptional regulators implicated in memory T cell development. | [{"id": "9500590", "score": 1}] | 435 | train |
65146a5f-7ae2-4fec-81ab-73ffa4f8679d | Long chain polyunsaturated fatty acids supplementation is associated with lower rates of atopic eczema at 1 year. | [{"id": "22442133", "score": 1}] | 709 | train |
a351625f-05b6-424e-902a-2c02b5d4dc63 | In the UK, drowning affects boys and girls equally. | [{"id": "42291761", "score": 1}] | 585 | train |
025a891c-a392-47bc-a116-e96760699bee | Foxp3 enables the expression of transcriptional regulators implicated in memory T cell development. | [{"id": "9500590", "score": 1}] | 434 | train |
1e627d55-4887-4ca4-a389-ff020f12beba | Chlamydia trachomatis is most prevalent in the UK among individuals in their 50s and 60s. | [{"id": "5850219", "score": 1}] | 255 | train |
0bce89d6-42f4-4b49-ac82-cc6df21c45d9 | Bariatric surgery increases rates of colorectal cancer. | [{"id": "5824985", "score": 1}] | 164 | train |
e7a2fcfa-fac5-481b-8ebe-fb940811ae4c | qSOFA scores are associated with length of stay in emergency department patients. | [{"id": "5185871", "score": 1}] | 1401 | train |
2ce2206f-3be5-4b0d-8d93-118ddd59e1dc | Antimicrobial agents are less effective due to the pressure of antimicrobial usage. | [{"id": "31460499", "score": 1}] | 121 | train |
35d3b6c5-51bd-4056-85ce-0f563b8a8dfe | In rhesus macaques, daily subcutaneous injections of tenofovir protects against rectally transmitted simian-human immunodeficiency virus. | [{"id": "14260013", "score": 1}] | 584 | train |
5dc3db65-6a5f-4d15-96c9-5de9f49585ec | In rhesus macaques, daily subcutaneous injections of emtricitabine are ineffective at protecting against rectally transmitted simian-human immunodeficiency virus. | [{"id": "14260013", "score": 1}] | 582 | train |
8f8ca56c-6460-40fd-901e-2c46948f76ab | Long - range chromatin interactions regulate transcription. | [{"id": "14658685", "score": 1}] | 704 | train |
f001df34-f6f6-48c5-b32a-c4d6edcee28d | Long chain polyunsaturated fatty acids supplementation has no significant effects on wheezing or asthma at 3 and 6 years. | [{"id": "22442133", "score": 1}] | 705 | train |
fe17d37a-697e-47a9-a241-34f5083a2362 | Chemical injury represses transglutaminase 2 activity. | [{"id": "13578199", "score": 1}] | 247 | train |
7e6fb228-048b-499d-bbea-8d36228d3c1d | Foxk2 regulates autophagy genes in muscle cells and fibroblast cells. | [{"id": "8002887", "score": 1}] | 432 | train |
f8c58627-b855-4e92-95dc-0c58cfd95684 | p75 NTR - associated cell death executor (NADE) interacts with the p75 NTR death domain | [{"id": "14706752", "score": 1}] | 1400 | train |
78c5c5c8-5749-48de-bf64-7e36211a0855 | FoxO3a activation in neuronal death is inhibited by reactive oxygen species (ROS). | [{"id": "28937856", "score": 1}] | 430 | train |
add2343d-83e8-42e2-b69d-4dc9869f95cb | Chenodeoxycholic acid treatment increases brown adipose tissue activity. | [{"id": "1568684", "score": 1}] | 251 | train |
3fda28b2-e376-4d1e-a31e-83440c782f44 | p16INK4A degradation is encoded by CDKN2A. | [{"id": "17717391", "score": 1}] | 1398 | train |
df67ace9-0a67-49fa-bd65-7c49c6843d89 | Localization of PIN1 in the roots of Arabidopsis requires VPS9a | [{"id": "4350400", "score": 1}] | 703 | train |
ecd3e2ab-6337-4bfe-9900-f4fb6bc712cc | In pediatric tissue, most T cells are naive T cell emigrants from the thymus. | [{"id": "23460562", "score": 1}] | 580 | train |
47f68895-f0c7-4769-89c5-5c4a08ff20c4 | Formation of N-terminal pyroglutamate by glutamine cyclase (GC) competes with NTAQ1 for Nt-Gln substrates. | [{"id": "36540079", "score": 1}] | 429 | train |
6dac8e04-bc80-4f08-9049-4022675150b1 | Chronic HIV stimulation of B cells leads to the premature exhaustion of B cells. | [{"id": "8883846", "score": 1}] | 259 | train |
69c07ec5-0454-4037-888d-de6804e04e14 | p16INK4A degradation is linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs). | [{"id": "17717391", "score": 1}] | 1397 | train |
7bb903e8-0e28-4486-a3b7-daaa37abd605 | Lmna knock-in models are appropriate for testing therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS). | [{"id": "22544171", "score": 1}] | 698 | train |
2e0a97be-18fd-4a9a-b1b5-3cbdf66e12eb | Forkhead 0 (fox0) transcription factors are involved in cellular differentiation. | [{"id": "16728949", "score": 1}] | 428 | train |
3349648e-ff33-446c-9c3b-8aae56f240eb | Chinese individuals with TT homozygosity in the MTHFR gene are less vulnerable to strokes caused by low levels of folate intake. | [{"id": "37424881", "score": 1}] | 253 | train |
7618f60c-3c95-44fe-8a7c-91c5c149a699 | In patients with congenital heart defects, β-blockers significantly improve clinical heart failure outcomes. | [{"id": "34139429", "score": 1}] | 579 | train |
534a4fd9-a937-4e9f-b3c5-f17eca1cc86b | miRNAs enforce homeostasis by suppressing low-level ''leaky'' transcription. | [{"id": "2000038", "score": 1}, {"id": "12440953", "score": 1}] | 1393 | train |
c8a00466-90f1-48e3-8cd2-b7c2e298ca12 | miRNAs regulate a unique suite of mRNAs to maintain homeostasis in cells. | [{"id": "2251426", "score": 1}] | 1394 | train |
7873147d-a5ce-420f-b59f-10ad9ba67be0 | Lipopolysaccharides have an inflammation independent effect on kidney barrier function. | [{"id": "16355392", "score": 1}] | 696 | train |
319bb2e4-f3c7-45e6-b120-839987b93449 | Chenodeoxycholic acid treatment decreases brown adipose tissue activity. | [{"id": "1568684", "score": 1}] | 250 | train |
33d8c746-6b75-4684-982e-086b270ad019 | In domesticated populations of Saccharomyces cerevisiae, segmental aneuploidy occurs infrequently. | [{"id": "10300888", "score": 1}] | 574 | train |
34331de5-5e6f-4e29-95e2-30e443283f32 | In melanoma, anti-CTLA-4 treatment reinvigorates exhausted PD-1+Eomes+CD8 T cells. | [{"id": "4468861", "score": 1}] | 576 | train |
193de728-d25d-4a8b-afa1-ff1e4d3b716a | For every 1,000 children with cerebral palsy, more than 300 of them are premature or underweight at birth. | [{"id": "33257464", "score": 1}] | 425 | train |
449fff9d-46eb-4b4e-929f-345159e7770e | Certain immunomodulator-human dialyzable leukocyte extract (hDLE) peptides are recognized by toll-like receptors (TLRs) on macrophages and dendritic cells. | [{"id": "21498497", "score": 1}] | 244 | train |
7e2ff367-1b54-490b-b0e6-6d044fa91141 | Forkhead 0 (fox0) transcription factors are involved in apoptosis. | [{"id": "16728949", "score": 1}] | 426 | train |
f1dbad2a-ec85-49cc-a19b-2591d9894a65 | Lice attenuated SIV vaccines induce a stronger antigen-specific T cell response in lymph node cells. | [{"id": "1071991", "score": 1}] | 694 | train |
151661be-f5d2-4dcf-9be8-a69ed1182787 | miR-142-5P is a temperature-sensitive microRNA (miRNA). | [{"id": "6766459", "score": 1}] | 1392 | train |
9ebf6c81-dfa3-4e61-9d93-3a55f52a6e41 | In domesticated populations of Saccharomyces cerevisiae, segmental aneuploidy is very common. | [{"id": "10300888", "score": 1}] | 573 | train |
b97fcba9-7ebf-4886-959b-cefcae1347d3 | Less than 10% of patients exposed to radiation have activated markers of mesenchymal stem cells. | [{"id": "22080671", "score": 1}] | 689 | train |
7adda5ab-cc95-4207-9e76-e542c2f031a6 | miR-142-5P is a known regulator of raised body temperature. | [{"id": "6766459", "score": 1}] | 1391 | train |
c318ab6c-b5d2-4fe3-a590-44d61f24b9d7 | Flexible molecules experience less steric hindrance in the tumor microenviroment than rigid molecules. | [{"id": "11172205", "score": 1}] | 422 | train |
0174b785-9df1-4bfe-9e0f-36c28e450b09 | Folate and vitamin B12 levels influence the association between homocysteine and preeclampsia. | [{"id": "8595678", "score": 1}] | 423 | train |
5a37098d-8310-41ed-91a9-457649775b5e | Charcoal shows no benefit for acute paraquat poisoning. | [{"id": "8447873", "score": 1}, {"id": "3430789", "score": 1}] | 246 | train |
d447f4cc-5c2b-4ae6-9505-9e5b5ed89c32 | Lamins have no effect on nuclear membrane structure maintenance. | [{"id": "4452659", "score": 1}] | 688 | train |
286b10db-a50e-4623-90e4-6982bcad7345 | In chronic viral infections or tumors, peptides that selectively inhibit PTPRS can be utilized to boost insufficient activity of pDCs. | [{"id": "4447055", "score": 1}] | 572 | train |
319acde9-cc80-4666-b668-daf71b99ed20 | Charcoal is an effective treatment for acute paraquat poisoning. | [{"id": "8447873", "score": 1}, {"id": "3430789", "score": 1}] | 245 | train |
cb68c2a4-2914-4072-a9af-60a0da262f29 | mcm 5 s 2 U is required for proper decoding of NNR codons in eukaryotes. | [{"id": "2890952", "score": 1}] | 1390 | train |
09df088d-1178-446d-adfa-824ac4ccb45c | Lamins are found within the inner layer of the nuclear membrane of all cells. | [{"id": "4452659", "score": 1}] | 687 | train |
abe526a2-34f7-491a-a901-da9673bf9f54 | In breast cancer, the loss of myoepithelial cells slows the transition of ductal carcinoma in situ to invasive carcinoma. | [{"id": "20333864", "score": 1}] | 571 | train |
b0e5c45a-639e-47a0-8592-00ab6f648e9f | eRNAs influence is linked to senescence, aging, and carcinogenesis. | [{"id": "9669099", "score": 1}] | 1387 | train |
5e413107-dad9-4665-b61c-bb42343a0b00 | Fibroblast growth factor 21 protects against atherosclerosis by modulating adiponectin and SREBP2 levels. | [{"id": "9315213", "score": 1}] | 420 | train |
10d252de-de74-4083-b155-6a6195f7b2bd | Fibroblast Growth Factor is a ligand which signals through receptor tyrosine kinases. | [{"id": "16660256", "score": 1}] | 418 | train |
8f319302-29f5-4009-b0ae-733a15ac92fd | cSMAC formation represses weak ligand signalling. | [{"id": "306006", "score": 1}] | 1386 | train |
30103cd4-5d4e-44e6-99dc-1ee17eeb9fd4 | In breast cancer, the loss of myoepithelial cells promotes the transition of ductal carcinoma in situ to invasive carcinoma. | [{"id": "20333864", "score": 1}] | 570 | train |
79175d69-0260-4fee-ad61-c17d052bbb52 | Cellular clocks are not predictive of mitosis timing in NIH 3T3 cells. | [{"id": "2212067", "score": 1}, {"id": "10608822", "score": 1}] | 242 | train |
ccd0049b-90de-4e3a-ae05-79e68537af14 | Cellular differentiation of embryonic stem cells is accompanied by changes in replication timing, transcription and nuclear localization. | [{"id": "8148122", "score": 1}] | 243 | train |
e25d02ee-9191-400f-b8f3-4d0b9f067193 | Lamins are found within the inner layer of the mitochondrial membrane of all cells. | [{"id": "4452659", "score": 1}] | 686 | train |
ff00b555-16d0-421c-813b-764b52f0b361 | Lamins are associated with nuclear membrane structure maintenance. | [{"id": "4452659", "score": 1}] | 685 | train |
3059a02e-b474-4022-b214-178c4dacd97f | In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells inhibits self-renewal of the mouse embryonic stem cells. | [{"id": "23418635", "score": 1}] | 568 | train |
30988db0-97ab-4d19-9594-29507f1fe668 | Female carriers of the Apolipoprotein E4 (APOE4) allele have shorter lifetime exposure to estrogen due to a decreased reproductive period. | [{"id": "6309659", "score": 1}] | 417 | train |
0bf1e69c-f645-41fd-ab35-7f871e1e9551 | Cellular clocks are associated with mitosis timing in NIH 3T3 cells. | [{"id": "2212067", "score": 1}, {"id": "10608822", "score": 1}] | 241 | train |
8442c2c3-45d0-4b70-9e5f-dd13ee94ae0a | aPKCz causes tumour suppression by affecting glutamine metabolism. | [{"id": "17755060", "score": 1}] | 1383 | train |
c58301bf-ccba-460c-b768-211a81d3bb2d | Cardiac tissue-resident macrophages directly contribute to electrical activity. | [{"id": "4928057", "score": 1}] | 228 | train |
374b8c7f-df62-4033-bf8f-726f847ce1a0 | In S. cerevisiae, the absence of RNA surveillance pathways causes sensitivity to high iron conditions. | [{"id": "16120395", "score": 1}] | 565 | train |
f41e9b5a-6370-4679-8eac-d285ffc47112 | In S. cerevisiae, the absence of RNA surveillance pathways reduces sensitivity to high iron conditions. | [{"id": "16120395", "score": 1}] | 566 | train |
4a5b7046-4525-4c50-99d3-a5a19d7f0ee3 | Lack of FGF21 in mice leads to reduced lifespan. | [{"id": "9315213", "score": 1}] | 682 | train |
7599ef6f-a532-4813-923d-57e6dd013a67 | YAP/TAZ is required in intestinal regeneration in mouse models of ulcerative colitis. | [{"id": "13481880", "score": 1}] | 1381 | train |
c5779ab1-a28d-4b58-85e7-5f73573ebc6f | Female carriers of the Apolipoprotein E4 (APOE4) allele have longer lifetime exposure to estrogen due to an increased reproductive period. | [{"id": "6309659", "score": 1}] | 416 | train |
cd7b318f-30c6-4f1b-b283-6941153d65f7 | Cell autonomous sex determination in somatic cells occurs in Galliformes. | [{"id": "4388470", "score": 1}] | 235 | train |
1a2b2eab-bf83-4de0-b2f9-34cb661d5476 | Lack of FGF21 in mice slows the rate of atherosclerotic plaque formation. | [{"id": "9315213", "score": 1}] | 683 | train |
0f65c761-af79-41d8-aaa3-63d309629c8b | Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for Alzheimer's disease. | [{"id": "6309659", "score": 1}] | 414 | train |
8bc4dc59-0630-4c3d-9452-fb3e03605742 | Women with a lower birth weight are more likely to develop breast cancer later in life. | [{"id": "16322674", "score": 1}, {"id": "23557241", "score": 1}, {"id": "17450673", "score": 1}] | 1380 | train |
fc21249a-1ae7-4a14-8047-da0c02a1d48e | Lack of FGF21 in mice leads to atherosclerotic plaque formation. | [{"id": "9315213", "score": 1}] | 681 | train |
650e1819-8a57-460e-8dcd-fba573201666 | Whole brain radiotherapy increases the occurrence of new brain metastases. | [{"id": "3944632", "score": 1}] | 1376 | train |
61b76fe2-494b-4a95-b52d-806330d54c82 | Women are more susceptible to death due to pneumonia when compared to men. | [{"id": "2488880", "score": 1}] | 1378 | train |
60cac86b-a4a2-4226-b2b5-3c2c9ce20b83 | Carriers of HNF4A mutations are at reduced risk for diabetes. | [{"id": "56893404", "score": 1}] | 229 | train |
b0afba00-3b40-4f19-8d10-c19692156c8e | In British Men, haplogroup I increases risk of cardiovascular disease by 50%. | [{"id": "2867345", "score": 1}] | 564 | train |
26c9de77-26b2-466a-9b3e-70f4e93d6990 | FACT and other histone chaperone(s) compensate for Histone 2A (H2A)-histone 2B (H2B) dimer eviction during the histone exchange process. | [{"id": "9889151", "score": 1}] | 407 | train |
f8ced569-5b57-40e3-b7a0-9577af8d1843 | Female carriers of the Apolipoprotein E4 (APOE4) allele have decreased risk for dementia. | [{"id": "6309659", "score": 1}] | 413 | train |
f665fe25-c5a1-464b-8581-6c1cf8f057fa | In British Men, haplogroup I decreases risk of cardiovascular disease. | [{"id": "2867345", "score": 1}] | 563 | train |
305d7d4d-3282-40ef-a53e-6b5a8638d736 | Cancers that initially benefit from epidermal growth factor receptor targeted therapies later become refractory through several mechanisms. | [{"id": "26973393", "score": 1}] | 227 | train |
45abcd9c-4ead-41c5-9d37-bccda4acd108 | Lack of FGF21 in mice increases life expectancy. | [{"id": "9315213", "score": 1}] | 680 | train |
cc19e1ba-02ed-416a-b042-c8473214d993 | LSD1-positive promoters are associated with RNA polymerase II | [{"id": "13639330", "score": 1}] | 679 | train |
33880515-5bd1-4891-b350-712a3dc09aed | Improvements in OER catalysts show stable activity over several hundred hours. | [{"id": "20101846", "score": 1}] | 562 | train |
e1ed8a1f-c6e4-40af-a835-09f679be821c | Expression of oncolytic virus antigens as peptides permits additional protection against relapse. | [{"id": "1921218", "score": 1}] | 404 | train |
16ad968e-3c60-4781-b0c5-1ebbeae3927f | Cancer cells can stimulate the accumulation of intra-tumoural myeloid-derived suppressor cells by promoting granulocyte colony stimulating factor production. | [{"id": "2014909", "score": 1}] | 223 | train |
a77fff1b-13ce-4cb0-8526-c279e216c8b9 | F4/80+ macrophages regulate mature osteoblast maintenance. | [{"id": "6796297", "score": 1}] | 406 | train |
d0e5be93-c1b6-4a1a-ab97-5c722564550f | Weighed food records (WFR) result in poor completion since they're costly to run and impose high participant burden. | [{"id": "21993510", "score": 1}] | 1375 | train |
424c9c29-3670-4bd2-9ed8-d6a4226bda25 | Immune responses in immune cells are geographically segregated. | [{"id": "3475317", "score": 1}] | 559 | train |
9e833028-614b-46d9-9884-030d0eab01b3 | Weighed food records (WFR) result in high completion since they're cheap to run and impose low participant burden. | [{"id": "21993510", "score": 1}] | 1374 | train |
8941e943-f5a1-402c-a248-06b7aeea7e0a | Cancer-associated fibroblasts (CAFs) interact with cancer cells to mediate formation and activation of CAFs. | [{"id": "6944800", "score": 1}] | 226 | train |
bc26bec9-a400-424d-b7e8-908106564679 | LRBA promotes CTLA - 4 recycling. | [{"id": "857189", "score": 1}] | 677 | train |
fc09677c-d913-4e3e-b927-8ee40ec25f82 | Immune complex triggered cell death leads to sequestration of oxidized mitochondrial DNA. | [{"id": "1049501", "score": 1}] | 557 | train |
382c77f0-53c7-4eb2-b409-699ce085eef4 | LRBA prevents CTLA - 4 recycling. | [{"id": "857189", "score": 1}] | 676 | train |
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