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Ans. is'd'i.e., Von Zumbusch typeVon Zumbusch type of pustular psoriasis is the suddenly developing most serious type, characterized by severe systemic upset, swinging pyrexia, ahralgia and high polymorphonuclear lymphocytes.The skin first becomes erythrodermic and then develops sheets of sterile pustules over trunk an...
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Ans. is 'a' i.e.t Promoter regiono These are the consensus sequences of DNA present on same chromosome, which is to be transcribed. These are - Promoter-proximal sequences (or simply promoters):- These are consensus sequences, which lies close to the initiation site of transcription. These can be divided into : -i) Pro...
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Pemphigus vulgaris and carcinomatous pemphigus (Pemphigus foliaceous) cause intraepidermal bullae.
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TOURE METHODS: The methods of toure are wide and varying. (I) PHYSICAL ABUSE : (1) Beating is the commonest form. Fist, foot or an instrument, such as lathi, metal or wooden bars, whips, belts, cycle chains, etc., are used. The usual target is the back, but injuries may be seen on almost any pa of the body. Abrasions, ...
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In 30deg flexion, knee joint has maximum capacity and pressure of contained fluid or blood is minimum and consequently, there is the least pain. The capacity of knee joint decreases and pain thereby increases when the knee is fully extended or flexed more than 30deg-45deg. Ref: Maheshwari 9TH ED pg 149.
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Juvenile myoclonic epilepsy is a subtype of idiopathic generalized epilepsy with onset usually between 8 and 20 years of age. Myoclonic jerks, especially in the morning, are of variable intensity ranging from simple twitching ("flying saucer syndrome") to falls; consciousness is not impaired in it. It is precipitated b...
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D i.e. Sternum Sex can be determined most reliably by medullary index of tibia, humerus, ulna and radiusQ
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Epidemiological triad The occurrence and manifestations of any disease, whether communicable or noncommunicable, are determined by the interaction of following three factors. The agent The host The environment These three factors together constitute the epidemiological triad. Mere presence of these factors does ...
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The supraspinatus initiates abduction of the arm during the first 15deg of abduction; palpation of the tendon during this phase would result in pain from a tendinopathy of the supraspinatus.
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This is a case of Phenylketonuria. Autosomal recessive Deficiency of Phenylalanine hydroxylase May also be due to deficiency of cofactor tetrahydrobiopterin BH4 Leads to hyperphenylalaninemia - Impairs brain development Normal at bih Becomes symptomatic later on in life Present with seizures, hypopigmentation of skin a...
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Ans: C. Events(Ref: Kaplan & Sadock 11/e p176-117; Niraj Ahuja 7le p14)Semantic memory is one of the two types of declarative or explicit memory.Refers to general word knowledge thst hte have accumnlated throughout our lives.This general knowledge (facts, ideas, meaning and concepts) is intewined in experience and depe...
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Pemphigoid neonatorum is a variety of bullous impetigo. Impetigo is a contagious superficial pyogenic infection. It can be bullous or non-bullous Causative organism: Bullous is caused by staph aureus Non bullous impetigo is caused by both Staph aureus and Strep pyogens Bullous disorder is widespread in neonate and was ...
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Immunologically the SLE. is associated with an enomorous array of autoantibodies , Classically include Anti nuclear antibody. Anti-DNA antibody to native DNA in abnormal tier Robbins 9 th edition page no. 125
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Enophthalmos (sinking of the eye) is the inward displacement of the eyeball. It results from paralysis of the orbitalis muscle (a smooth muscle that spans the inferior orbital fissure and may contribute to maintaining the normal position of the eyeball). Ref: Gray's Basic Anatomy By Richard Drake, A. Wayne Vogl, Adam W...
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Lack of initiation may result in oligodontia or anodontia. Abnormal initiation may result in supernumerary teeth.
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Unequal sizes of twin fetuses with a difference of 25% (larger twin being used as the index), is called as Discordant growth. It is a sign of pathological growth restriction in the smaller fetus. As the weight difference within a twin pair increases and the earlier the growth discordance is evident, perinatal mortalit...
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Ans. (d) ZincImportant minerals and their respective action as cofactorMineralsFunctionSelenium* Cofactor for# Glutathione peroxidase# Deiodinase# Thioredoxin reductaseManganese* Cofactor for:# Arginase# Kinase# Carboxylase# Glucosyl transferase# EnolaseZinc* Cofactor for:# Carbonic anhydrase# Alcohol dehydrogenase# La...
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Ans. D i.e. All of the above Mechanism of death: Cerebral anoxia: is due to bilateral occlusion of the carotid aeries. It is the most common cause. Cerebral congestion: is due to occlusion of the neck veins. Asphyxia: is due to direct compression of the air passages or lifting of the larynx to be closed by the root of ...
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Ans. b. Congenital adrenal hyperplasia Autosomal dominant "Very Powerful DOMINANT Humans" V- Von willibrands disease/ Von hippel lindau P - Pseudo hypoparathyroidism D - Dystrophia myotonica O - Osteogenesis imperfecta/Osler-weber-rendu M - Marfans syndrome I - Intermittent porphyria N - Neurofibramatosis A - Achondrop...
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Ans. is 'd' i.e., Seminoma
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A i.e. Aoic arch; C i.e. Left ventricle; B i.e. Left Pulmonary aery
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Exeional dyspnea, angina pectoris, and syncope are the three cardinal symptoms of AS. Often, there is a history of insidious progression of fatigue and dyspnea associated with gradual cuailment of activities. Dyspnea results primarily from elevation of the pulmonary capillary pressure caused by elevations of LV diastol...
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D. i.e. Papilloma virus
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Steady state is achieved when rate of administration is equal to rate of elimination Three impoant points to remember: Steady state is achieved within 4-5 half lives Dosing rate (dose per unit time) determines the average plasma concentration obtained at steady state. Frequency - drug when given intermittently, concent...
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IgG is diagnostic Repeat .from May 10 Q no.122
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This is a case of minimal change disease(MCD) On biopsy-no lesion is seen by light microscopy, negative for deposits by immunofluorescent microscopy -so it is also called nil lesion. On electron microscopy -effacement of foot processes suppoing Glomerular cells(podocytes) with weakening of slit pore membranes is seen. ...
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The decrease in O2 affinity of hemoglobin when the pH of blood falls is called the Bohr effect. It is closely related to the fact that deoxygenated hemoglobin (deoxyhemoglobin) binds H+ more actively than does oxygenated hemoglobin (oxyhemoglobin). The pH of blood falls as its CO2 content increases, so that when the PC...
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According, the rate of systemic absorption is greatest with intercostal nerve blocks followed by caudal, lumbar epidural, brachial plexus block femoral and sciatic nerve blocks. Sequence of systemic absorption IV > Tracheal > Intercostal block > Para cervical block > Caudal > Lumbar epidural > Brachial Plexus > Sciatic...
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Ans. a (The vaginal finger is at ischial spine) (Ref. Dutta Obst 6th/353)Muller introduced the abdominovaginal method of diagnosing CPD at the brim by placing the vaginal finger at the level of ischial spine to note the descent of the fetal head.Munro-Kerr added placement of the thumb over the synmphysis pubis to note ...
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Hypoglycemia is the most common cause of seizure in an infant of diabetic mother within 24hours of delivery. Ref: NMS Pediatrics By Paul H. Dworkin, Paula S. Algranati page135.
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Ans. is 'a' i.e., Congenital
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Intracellular
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Deep palmar arch- Fed by radial aery, Lies deep to lumbricals Gives three perforating and three palmar metacarpal aeries.
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Ans. (b) Sympathetic ophthalmitisRef: A.K. Khurana 6th ed. /163y 437* Sympathetic ophthalmitis is a serious bilateral granulomatous panuveitis which usually occurs due to penetrating trauma to ciliary body.* The injured eye is called exciting eye.* Fellow eye which also develops uvieitis is called sympathizing eye.Feat...
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Ans: b (Cloxacillin) Ref: Tripahti, 6th ed, p. 699Classification1. Acid resistant alternative to pencillin G Phenoxymethyl penicillin (Penicillin V)2. Penicillinase resistant penicillins: Methicillin, cloxacillin3. Extended spectrum penicillina) Aminopenicillin: Ampicillin, bacampicillin, amoxicillinb) Carboxypenicilli...
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liddle syndrome severe hypeension Hypokalemia and metabolic alkalosis Polyuria polydipsia and muscle weakness low aldosterone and reninn levels Autosomal dominant Blood pressure does not improve with Aldactone but does improve with triamterene or amilor-ide Other Causes of Hypeension and pokalemia Renovascular Disease ...
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(B) Group B
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The normal urothelium is composed of 3-7 layers of transitional cell epithelium. It is characterized by a superficial layer of dome like cells that are neither squamous nor columnar. These cells, sometimes called umbrella cells. It lines,Walls of the calicesPelvisUrinary bladderUretersUpper pa of the urethra
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In Cu T 200, the number included in the name of the device refer to the surface area in sq.mm of the copper on the device Reference : Park&;s textbook of preventive and social medicine,23rd edition, Page no: 496
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Busiprinone, is a medication primarily used to treat anxiety disorders, paicularly generalized anxiety disorder. Benefits suppo its sho term use. It is not useful for psychosis. It is taken by mouth, and it may take up to four weeks for an effect Ref KD Tripati 8th ed.
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A i.e. Analgesic with arm sling
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Ans. is 'b' i.e., 48 hours * Human Chorionic Gonadotropin (hCG): Glycoprotein, with biological activity very similar to luteinizing hormone (LH), both of which act via the plasma membrane LH-hCG receptor. It is secreted by syncytiotrophoblasts.* This hormone is structurally related to three other glycoprotein hormones:...
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Obstructed labour
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South Hampton grading Scale is used for surgical site infections. SURGICAL SITE INFECTIONS A major SSI is defined as a wound that either discharges significant quantites of pus spontaneously or needs a secondary procedure to drain it. The patient may have systemic signs such as tachycardia, pyrexia and a raised WBC cou...
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CERVICAL VEEBRAE They are identified by the presence of foramen transversaria.There are seven cervical veebrae,out of which the third to sixth are typical,while the first,second and seventh are atypical. Typical cervical veebra Body 1.The body is small and broader from side to side than from before backwards. 2.The sup...
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Insulin is administered subcutaneously. MMR vaccine, heparin are also given by SC route All others are by intradermal route. (Ref.Essentials of medical pharmacology TD Tripathi 6th edition page no.263)
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- Field instrument to measure bih weight is Salter's Spring balance (kind of sling balance on which child is hung) - Average bih weight = 2.8kg - According to WHO, Low bih weight = < 2.5kg Very Low bih weight = < 1.5 Kg Extremely Low bih weight = < 1 Kg - Bih weight Doubles by 5 months Triples by 12 months Quadruples b...
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Systemic steroids are not required in DH Dapsone is D.O.C. S/E of Dapsone: Hemolysis and Methemoglobinemia.
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Septic shock is most common cause of death. Asphyxia is MCC death in immediate phase of burns.
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Caudate lobe lies anterior to crura of diaphragm, right inferior phrenic artery and coeliac trunk. Caudate lobe is superior to portal vein (lies in porta hepatis) and to right of ligament venosum.
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Effects of tamoxifen Tamoxifen is an S.E.R.M (selective estrogen receptor modulator) Increase risk of endometrial cancer Decrease risk of osteoporosis Useful in breast cancer Menopausal symptoms like hot flushes
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Any object that compromises the blood supply to the tracheal mucosa or cartilage can cause stenosis. When the mean intramural pressure exceeds 20-30 mm Hg, damage may be anticipated. Riedel struma is a rare fibrosing thyroid condition, which must be differentiated from carcinoma and may cause severe tracheal stenosis. ...
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Transfection is the method by which DNA is transferred into eukaryotic cell.
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Ans. is 'a' i.e., Line diagramLine diagram 1 Line chart/Line graph)o It is used to show the trend of events with passage of time and shows how the frequency of a particular event or variable vary over time. DataMethodFrequency of occurrence (comparisons of magnitude)Bar ChartPie chartTrends over timeLine graphDistribut...
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Ans. is c i.e. LSCS When a patient with transverse lie is seen in labour, it is managed as follows according to Dutta Obs. 6/e, p 397. Early labor ECV - provided there is good amount of liquor amnii and there is no contraindication. ECV should be tried in all cases. LSCS - is the preferred method of delivery if version...
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Saturnine gout Cause - Lead toxicity Symptoms - Symptoms of lead toxicity precede the development of gout. Hence patient will have anemia, basophilic stippling of RBC, abdominal pain and nerve palsy The damage to kidney will lead to hypeension and progressive renal malfunction. Knee joint involvement is more common tha...
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Ans. (c) Sweat electrolytesRef: Harrison's Medicine 18th ed p 2149-50
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Lupus affects anterior part of larynx. It starts at the epiglottis and sspreads posteriorly to involve aryepiglottic folds. Slow indolent and symptomless destruction of epiglottis may occur. Lupus of larynx is secondary to lupus of nose and pharynx.Contact ulcer occurs at vocal process of arytenoid when one vocal proce...
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Ans: d) tricuspid valve prolapse It is mitral valve prolapse and not tricuspid valve prolapse that is classically associated with ADPCKDADPCKD:-* Inheritance: AD with high penetrance* Universally bilateral* Mutations - ADPKD1 - Ch. 16ADPCKD2 - Ch. 4* Renal function retained till 4th - 5th decade* PKD1 gene encodes Poly...
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Ans. is 'b' i.e., Presence of abdominal painBacillus cereus food poisoning is of two types. Emetic type and Diarrheal type. Abdominal cramps are common feature in both. Other features are:(a) Emetic Type: History of intake of fried rice from Chinese restaurant 6 hours earlier. Mediated by enterotoxin resembling Staphyl...
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Ans. is 'b' i.e., 150 ml o Total capillary blood valume in lung- 104 ml.o Total pulmonary capillary surface area - 70 m2o Volume of blood per alveolus - 4.7 x 10-7 ml.o Capillary surface area per alveolus - 23.4 x l04 cm2o Number of capillary segments - 280 x 109
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Ans. B. 24 mm In adults the external acoustic meatus measures about 24 mm from the introitus to the tympanic membrane, which is its medial limit.
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Ans. (C) Allopurinol(Ref: KDT 8th/e p217)*NSAIDs like naproxen have no role in chronic gout*Uricosuric drugs like probenecid and sulfinpyrazone are ineffective in the presence of renal insufficiency*Allopurinol is drug of choice for most cases of chronic gout.
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Ans. is 'a' i.e., Celecoxib o COX-2 inhibitors are i) Celecoxib iii) Valdecoxib v) Rofecoxib ii) Etoricoxib vi) Lumitracoxib vi) Parecoxib
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d. GnRH agonists(Ref: Nelson's 20/e p 2658)Nelson latest ed says: "Long-acting formulations of GnRH agonists, which maintain fairly constant serum concentrations of the drug for weeks or months, constitute the preparations of choice for treatment of central precocious puberty."
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Premolars are absent in temporary dentition.
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Joints taking part in inversion and eversion of foot. Principal joints- Subtalar, talocalcaneonavicular Accessory joints- calcaneocuboid, talonavicular
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ANTERIOR COLPORRHAPHY An inveed T incision is made on the anterior vaginal wall. the horizontal incision is made below the bladder and the veical incision is made staing from the midpoint of the tranverse incision upto a point about 1.5 cm below the external urethral meatus. The traiangular vaginal flaps including the ...
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Ans. is 'b' Hepatic disease Make it clear once and for all that Digitalis is the parent compound. Digitalis is applied as a collective term for the whole group and has come to mean a cardiac glycoside.Digoxin and digitoxin are two of the many types of cardiac glycoside.Digoxin is a polar glycoside, and is excreted by k...
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Ans. C. Ovarya. Mullerian duct is a mesodermal derivative and gives rise to uterus and uterine tubes. It also forms mesodermal part of the vagina when it meets with the Sino-vaginal bulbs. Sino-vaginal bulbs are induced by the mullerian duct and they form the lower (endodermal) part of vagina.b. Now if mullerian ducts ...
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The diagnostic criteria of NCPF includes splenomegaly, normal liver function test, esophageal varices (90-95% cases), patent hepatic and poal veins and no evidence of cirrhosis on biopsy. Based on this criteria, the most probable diagnosis in this patient is Non cirrhotic poal fibrosis. Ref: Arun J. Sanyal, Vijay H. Sh...
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Ans. is 'b' i.e., Epitheloid cell
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Ans. D. ALA dehydratasePaints contain lead hence it is most probably lead poisoning. Biochemical effects of lead poisoning are:Inhibition of ALA dehydratase >> Ferro chelataseIncreased ALA excretion in urine. Increased ALA synthase activity.
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Intra-orbital is the longest pa of optic nerve. Cranial Nerve Optic nerve arises from ganglion cell axons. Length = 50 mm. (40 mm in few texts) Can be considered as pa of brain 2nd order neuron Pas: Intraocular(1), Intraorbital(2), Intracanalicular(3), Intracranial(4). Smallest pa of optic nerve is Intraocular Longest ...
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In posterior dislocation of hip, the limb is held in flexion, adduction and internal rotation. It's the opposite in anterior dislocation. The treatment is emergency reduction of the dislocated hip. Ref: Essential Ohopedics By J Maheswari, 2nd Edition, Pages 181-183
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Ans. D. Factitious disorderFactitious disorderIt is also known as Hospital addiction, hospital hoboes, or Professional patient.The term Munchausen syndrome is used for those patients who repeatedly simulate or fake diseases (intentionally) for the sole purpose of obtaining medical attention. There is no other recogniza...
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Ans. is 'b' i.e., Varicella Tzank smear findings in bullous disordersDisordersFindingso Pemphiguso Bullous pemphigoido Varicella-zoster infectiono Herpes simpex infectiono Toxic epidermal necrolysisAcantholysisPredominantly eosinophilsMultinucleated giant cellsMultinucleated giant cellsNecrotic cells
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Zika virus is a mosquito- borne flavivirus which is transmitted through the bite of infected Aedes Aegypti. Transmission from an infected pregnant mother to her baby during pregnancy or around the time of bih is also a possibility. Zika Virus Zika virus is a mosquito-borne Flavivirus Caused by Zika virus which belongs ...
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DORSIFLEXION FOOT:- The forefoot is raised,and the angle between the front of the leg and the dorsum of the foot is diminished. The wider anterior trochlear surface of the talus fits into the lower end of narrow posterior pa of the lower end of tibia. No chance of dislocation in dorsiflexion. PLANTAR FLEXION OF FOOT:- ...
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Smith Patersen Nail was previously used for internal fixation of fracture neck of femur. IMAGE OF ENDERS NAIL Ref : Maheswari 9th ed
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In mature erythrocytes the major available anion is ClRef: Ganong&;s review of medical physiology 23rd edition Page no: 523
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Answer is B (Verbal expression): Motor aphasia also known as expressive aphasia is a disorder of thought and word finding resulting in inadequate verbal expression. * Defect in hearing: Deafness * Defect in understanding: Receptive aphasia / Sensory aphasia * Defect in thought and word finding: Motor / Expressive aphas...
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a) Congenital syphilis: Hutchinson's triad: Hypoplastic incisors and molars, interstitial keratitis, 8th nerve deafness. Saddle nose Sabre tibia Rhaghades (radiating scars around mouth, nose and  anus) • Bossing of frontal and parietal bones Hypoplastic maxilla Salt and pepper scars on retina. b) Primary syphilis: P...
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a. Refusal to suck, poor cry and lethargy are common features(Ref: Nelson's 20/e p 918-922)Discussing the options one by one,a.True; These are the earliest and very common features of neonatal sepsisb.False, Neutropenia & not neutrophilia is a feature of neonatal sepsisc.False, Sepsis can occur anytime in the neonatal ...
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Answer: b) Inability to oppose the thumb to other digits.Patient is suffering from "carpal tunnel syndrome".It is a medical condition in which the median nerve is compressed as it passes through the carpal tunnel deep to the flexor retinaculum at the wrist.The patient's occupation as typist may have predisposed the pat...
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Ans. is 'b' i.e., Epinephrine injection Generalized uicaria, swelling of lips, hypotension and bronchospasm within 5 minutes of taking penicillin suggest the diagnosis of anaphylactic type of hypersensitivity. Epienephrine (S.C./i.m.) is DOC for anaphylactic shock.
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The umbilical cord, surrounded by the amnion, contains two umbilical aeries, one umbilical vein and Whaon&;s jelly, which serves as a protective cushion for the vessels. Single Umbilical aery is associated with other congenital anomalies and observation of a two-vessel cord with a single umbilical aery in a new born sh...
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Treatment includes: 1. Coicosteroids administered systemically and as repeated periocular injections may be effective in some cases. 2. Immunosuppressive drugs may be helpful in steroid-resistant cases. 3. Peripheral cryotherapy is also repoed to be effective. with most forms of uveitis, coicosteroids are the mainstay ...
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Ans. is 'b' i.e.. Anemometer
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Unlike the external carotid aery, the internal carotid normally has no branches in the neck. Branches of the internal carotid aery Memonic: A VIP'S COMMA A: anterior choroidal aery V: Vidian aery I: inferolateral trunk P: posterior communicating aery S: superior hypophyseal aery C: caroticotympanic aery O: ophthalmic a...
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The presentation of shock is variable with some people having only minimal symptoms such as confusion and weakness. While the general signs for all types of shock are low blood pressure, decreased urine output, and confusion, these may not always be present.While a fast hea rate is common, those on b-blockers, those wh...
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Ans. is 'b' i.e., SmokingThromboangitis obliterans (Berger disease) o Thrombangitis obliterans is a distinctive disease that is characterized by segmental, thrombosing acute and chronic inflammation of medium sized and small sized aeries, and sometimes secondarily extending to veins and nerves.o Thromboangitis oblitera...
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FRAMINGHAM HEART STUDY: Is a classical example of cohort study Initiated in 1948 by US Public Health Service at Framingham, a town in Massachusetts, USA Aim: To study the relationship of risk factors (serum cholesterol, blood pressure, weight,smoking) to the subsequent development of cardiovascular diseases.
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Ans is a Follicular
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(Decidua-parietalis) (25, 36-Duta 6th)Decidua-vera or parietalis - the rest of the deciduas lining the uterine cavity outside the site of implantation.* Foetal blood now circulate through the villi, while maternal blood circulate through intervillous space (69-IBS- Embryology 7th)* Synocytiotrophoblast grows into the e...
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"Peripheral neuropathy strongest association is seen stavudine and zalcitabine" Major dose limiting side effects of retroviral drugs 1. Didanosine - pancreatitis, neutropenia 2. Stavudine peripheral neuropathy, pancreatitis 3. Zidovudine bone marrow suppression 4. Lamivudine -- nil and least toxic 5. Zalcitabine - peri...
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The inferior margin of pleura extends onto diaphragm at the level of (Costodiaphragmatic line) -        8th rib in the midclavicular line -        10th rib in mid-axillary line -        12th rib at the lateral border of erector spinae. The lower border of lungs extends till the level of -        6th rib in the midclavi...
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Bullous pemphigoid is an autoimmune pruritic skin disease preferentially in elderly people, that may involve the formation of blisters (bullae) in the space between the epidermal and dermal skin layers. The disorder is a type of pemphigoid. It is classified as a type II hypersensitivity reaction, with the formation of ...
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All of them contribute to the stability of the knee joint but The vastus lateralis muscles arise from the femur and all the other muscles originate from the hip (coxal) bone.
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Dendritic cells are a form of antigen-presenting cell. Dendritic cells in epithelia are known as Langerhans cells, and those within germinal centers are called follicular dendritic cells (FDCs). The FDCs may become infected but not killed by HIV. They have cell surface Fc receptors that capture antibody-coated HIV viri...
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