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Ans. is 'a' i.e., VDRL for mother and Baby Bullous lesion and periostitis suggest the diagnosis of congenital syphilis. o The only option related to syphilis is option 'a'. o Following evaluations are recommended : - 1. Physical examiation 2. A quantitative nontreponemal test for syphilis (VDRL). 3. CSF for cell count,...
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Ans. is 'a' i.e., True negative result
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The diagnosis in the question points towards the diagnosis of Baholin's cyst. Though both surgical resection and marsupialisation are used in the surgical management, the latter is preferred more due to its advantages. Incision and drainage would be appropriate for Baholin's abscess. Aspiration would lead to recurrence...
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Ans is "b" i.e. Nasopharyngeal carcinoma Note: Glottic carcinoma never metastasizes to lymph nodes and carcinoma lip metastasizes rarely and very late
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Ans. is 'a' i.e. Verapamil belongs to second group drugs Verapamil is a calcium channel blocker. It belongs to class IV anti-arrhythmic drugs. Electrophysiological properties of verapamil. Among the Ca2+ channel blockers, verapamil has the most prominent cardiac electrophysiological action. It is a cardio depressant dr...
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Whole-body iodine scan is recommended for differentiated thyroid cancer , which fulfill following conditions : Tumors - between 1cm-4cm Confined to the thyroid Do not have nodal or distant metastasis, Adverse histologic subtype (tall cell) Vascular invasion. =Unlike differentiated thyroid cancer, Medullary thyroid carc...
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Certain tumors are known to be common sources of bone metastasis. The following primary tumors are the most common to metastasize in the bone; breast, prostate, lung, thyroid, kidney, and gastrointestinal tract. The commonest source of metastatic bone disease is carcinoma of the breast. In males most common source is p...
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Free fatty acids bound to albumin are increased as a result of an increased activity of Hormone sensitive lipase in adipose tissue as this enzyme breaks TG into glycerol & fatty acids. These fatty acids are taken up by liver. b-oxidation of these fatty acids in liver provides the acetyl CoA for ketogenesis. Hepatic ket...
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HAA is given in AIDS patients, and has proved to be very effective in decreasing the viraemia and improving the CD count. Incidence of CMV retinitis is markedly decreased in such patients. But due to the improvement in the immunity, the patient stas developing uveitis.
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Zika virus disease is caused by a virus transmitted primarily by Aedes mosquitoes, which bite during the day. Symptoms are generally mild and include fever, rash, conjunctivitis, muscle and joint pain, malaise or headache. Symptoms typically last for 2-7 days. Most people with Zika virus infection do not develop sympto...
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The primary bacterial indicators of contamination of water are the coliform group. Supplementary indicators include faecal streptococci and sulphite-reducing clostridia(C.perfringens) Park's Textbook of Preventive and Social Medicine, 25th edition, Page No. 780,781
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Mucoid colonies are due to the production of the capsule of hyaluronic acid not due to M-protein. Growth characteristic of Strep. pyogenes: On blood agar, virulent stains form matt or mucoid colonies while avirulent from glossy colonies. M, T, R are proteins found on the outer pa of the cell wall and forms the basis of...
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Ans. is 'c' i.e., Infected person harbouring infectious agent without clinical features and acts as source of infection Sources and reservoirs* Source is 'the person, animal, object or substance from which infectious agent passes to host\ i.e. man acquires infection from source.* Reservoir is 'any person, animal, insec...
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Ans. is 'b' i.e., ABER Annual blood examination rate (ABER) is an index of operational efficiency.
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Ans. b. Dehiscent superior semicircular canal Dehiscence of bone overlying the superior semicircular canal can cause a constellation of vestibular and auditory symptoms and signs. These abnormalities can be understood in terms of the effect of the dehiscence in creating a third mobile window into the inner ear.
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Ans. is 'b' i.e., 7 years
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(A) Myopia > In myopia, the axial length of the eyeball is increased while in hypermetropia, the axial length of the eyeball is decreased.
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It is necessary to employ suckling mice for the isolation of coxsackie virus. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO:491
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Ans. is 'd' i.e.. Inferior epigastric artery Contents of inguinal canalo Spermatic cord in male or round ligament of uterus in female.o Ilioinguinal nerve : It enters through the interval between external and internal oblique muscles,\o Genital branch of genitofemoral nerve is a constituent of spermatic cord.
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(Isoflurane) (134-Lee's 13th) (373 - KDT 6th)ISOFLURANE - Repeated iso flurane administration have failed to produce measurable changes in liver function Renal and hepatic toxicity has not been encountered.* Anaesthetic choice in - Neurosurgery and safer in myocardial ischaemiaSEVOFLURANE - anaesthetic choice in Liver ...
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Sarilumab: Monoclonal antibody against IL6, used for rheumatoid ahritis. Six - SARILUMAB - monoclonal antibody | Interleukin Durvalumab: Monoclonal antibody for urothelial carcinoma. DURVALUMAB - Urothelial Ca Nivolumab/Sarilumab: Monoclonal antibody for non small cell lung cancer(NSCLC). Durvalumab, Nivolumab, Sarilum...
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Cryoprecipitate has a higher concentration of Factor VII (80 IU in 15 ml of plasma) compared to FFP (200 IU in 200 ml). Thus, cyroprecipitate has a higher concentration on Factor VIII.
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An elevated alkaline phosphatase level in an older adult should raise the suspicion of bone metastases, particularly when there is a "pathologic" fracture resulting from a bone lesion, rather than a fracture from trauma. Likely primary sites include the breast (in women), prostate (in men), lung (in smokers), kidney, a...
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Serotonin is a vasoconstricting hormone, produced in the brain and GI tract. In the GI tract it is produced normally by enterochromaffin cells (argentaffin cells). The principal function is to regulate smooth muscle contraction and peristalsis. Serotonin: also called 5-hydroxytryptamine, is a chemical substance that is...
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These drugs act by Nucleoside reverse transcriptase inhibition
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Intermediate host-man Definitive host-mosquito Asexual development-man Sexual development-mosquito Sporozoite infective form.Sporozoites are present in the salivary gland of the mosquito .Man gets infection by the bite of female anopheles mosquito (refer pgno:55 baveja 3 rd edition)
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Rubella infection is acquired by inhalation or transplacental route. Ref: Baveja textbook of microbiology; 4th edition
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To differentiate color coding is given to the cylinders . Blue - N20 Black - N2 Orange - Cyclopropane Grey - Co2 Black body with white shoulder - O2 Black body with brown shoulder - Heliox ( Helium + 02 )
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Testicular feminization syndrome (androgen insensitivity syndrome): XY karyotype with a female phenotype androgens are present but do not act at a peripheral level due to a receptor defect. the embryological development, which is dependent on androgens in a male fetus, does not happen and hence by default a female form...
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Post pattum hemorrhage is the main cause of maternal deaths. It account for about 25%.REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 516
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Abductor pollicis brevis and flexor pollicis brevis, both are supplied by the median nerve. However, flexor pollicis brevis cannot be tested separately because flexion of metacarpophalangeal joint of the thumb (the function of flexor pollicis brevis) can also be produced by flexor pollicis longus. On the other hand abd...
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Ans. a. Amoebic dysentery
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Ans. (a) Diabetes mellitus (b) Total parenteral nutrition (c) Tuberculosis * In acalculous cholecystitis, there is acute inflammation of gallbladder without gallstones.* In over 50% of cases of acalculous cholecystitis an underlying explanation is not found.* Acalculous cholecystitis typically develop in critically ill...
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Ans. is 'b' i.e., Fecal-oral route . Polio transmission is mostly restricted to developing countries where fecal-oral route is the most common mode of transmission.
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Streptococcal pyrogenic toxin (SPE) is also called erythrogenic or Dick or scarlatinal toxin. This toxin was named 'erythrogenic' because its intradermal injection into susceptible individuals produced an erythematous reaction. SPEs are superantigens which are T cell mitogens that induce a massive release of inflammato...
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Foley's catheter
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A solitary hypoechoic lesion without any septae or debris is most likely to be a simple cyst. However rarely a hydatid cyst can have a similar sonologic appearance. Simple cysts are the most common benign lesions found in liver. On imaging studies they appear as unilocular, homogenous fluid-filled structures with a thi...
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Ans. is 'b' i.e., Agglutination of ricketssial suspension * Both epidemic typhus and endemic typhus are positive for OX-19 antigen - Thus Weil Fleix reaction cannot differentiate between the two.Serological diagnosis of Rickettsial infection* Serological diagnosis may be made by :-i) Heterophile Weil-Felix reaction.ii)...
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Ans. is 'b' i.e., Tumours derived from Rathke's Pouch Craniopharyngiomao Craniopharyngioma is a type of brain tumor derived from pituitary gland embryonic tissue that occurs most commonly in children but also in men and women in their 50s and 60s. People may present with bitemporal inferior quadrantanopia leading to bi...
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In addition to the three basic principles of radiation protection (justification, limitation, and optimization), one  can apply the following additional techniques to reduce the radiation burden to the patient: Collimation of the x-ray beam. Correct focus-to-skin distance. Lead apron with thyroid collar. More radiatio...
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Craniofacial abnormalities are common in O.S.A in non-obese patients and children. Non structural risk factors for OSA include: Obesity, central fat distribution Male sex, middle age Alcohol use, sedative use, smoking Supine sleep position
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Ans. B. Eleks gel precipitation testNeil Mooser reaction is done in guinea pigs for Rickettsia rickettsiae (Scrotal necrosis) and tunica reaction (Rickettsia conorii, Rickettsia akari and Rickettsia typhi)
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Restless leg syndrome / Ekbom syndrome. Sensorimotor disorder, commonly seen in 5-15% of the population. Affects females and after 40 years. 4 salient diagnostic features being: Urge to move limbs, commonly associated with premonitory sensory discomfo Motor restlessness Relief by activity Evening/Night worsening Pathop...
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Cholecystovenacaval line: - Is an imaginary line which passes through groove for IVC to the gallbladder fossa and separates right & left hepatic lobe functionally.
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A small medial area of the superior pole is related to the left suprarenal gland. Approximately the upper two-thirds of the lateral half of the anterior surface is related to the spleen. A central quadrilateral area lies in contact with the pancreas and the splenic vessels. Above this a small variable triangular region...
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sho-acting beta2 agonists- salbutamol., terbutaline, pirbuterol long-acting- salmeterol, formoterol, clenbuterol ref kd Tripathi 8th ed
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.question repeated
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Hanup disease - autosomal recessive disease due to mutation in SLC6A19 which cause: Inability to absorb neutral amino acid from intestine and renal cell Tryptophan absorption is severely affected. C/f Pellagra like symptoms- As tryptophan is required for Niacin synthesis. amino aciduria Increased urinary output of indo...
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Behavioral therapy like using alarms is the treatment of choice for Nocturnal enuresis. Desmopressin is the drug of choice for Nocturnal enuresis although Imipramine and Oxybutynin are also used.
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Answer- C. Erosion of epithelium + underlying inflammationCorneal ulcer refers to discontinuation in normal epithelial surface of cornea associated with necrosis of the surrounding corneal tissue
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Ans. is 'c' i.e., Corynebacterium diphtheriae
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Long Bone Diaphysis (shaft) - derived from primary ossification center. * present at 6 - 8 weeks of IUL. Epiphysis (ends) - derived from secondary ossification center. * appear after bih Except - Lower end of femur & sometimes upper end of tibia. | Their secondary ossification center appears before bih.
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(B) tricuspid incompetence # Tricuspid regurgitation causes the v wave to be more prominent; when tricuspid regurgitation becomes severe, the combination of a prominent v wave and obliteration of the x descent results in a single large positive systolic wave.> After the v wave peaks, the right atrial pressure falls bec...
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Answer is A (Protein| sugar|): CSF proteins are increased and glucose levels are characteristically decreased.
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The infectious agents listed are all impoant causes of congenital disease. The triad of cutaneous hemorrhages ("blueberry muffin baby"), deafness, and periventricular CNS calcifications suggests congenital CMV infection, the most common cause of intrauterine fetal viral infection. Other manifestations include microceph...
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Ans. A. Combination should be avoidedRef: Harrison's Principles of Internal Medicine 19th/ed, p2147Explanation# Option a: Anakinra (IL 1 antagonist) and infliximab (anti-TNF) should not be combined.# Both agents restrict inflammatory process markedly and lead to high rate of serious infections.# This finding is observe...
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Village health guides A village health guide is a person with an aptitude for social service and is not a full time government functionary. The health guides are now mostly women. The health guides come from and are chosen by the community. They serve as links between the community and the government infrastructure an...
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Ans is a i.e. anencephaly
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Complicatiosn of Talar neck fracture Malunion                    Avascular necrosis (osteonecrosis) of body. Non-union   Secondary osteoarthritis of ankle and subtalar joint.
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Primary causes of microcephaly in children are - Mnemonic - Cannot See PEFR in Children Cri-du-chat Syndrome Smith Lemli Optiz Syndrome Patau syndrome Edward syndrome Familial Rubinstein Taybi syndrome Cornelia de Lange syndrome Also Know Acquired MIcrocephaly Q R - Rett's syndrome A - Angelmann Syndrome S - Seckel syn...
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Aoic Stenosis REF: Harrison's 17th ed chapter 220 Anacrotic pulse with a slow initial upstroke, the peak is close to S2; these features suggest fixed left ventricular outflow obstruction, such as occurs with valvular aoic stenosis
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> 8 days
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i.e. (Mitochondria) : (301-Harsh Mohan 6th ) (625-Robbins & Cotran-Pathologic basis of disease 8th)Ringed sideroblasts is characteristic of sideroblastic anemia /Myelodysplastic SyndromeRinged sideroblast in which haem synthesis is disturbed as occurs in sideroblastic anaemiasRinged sideroblasts containing numerous lar...
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The criteria to diagnose a right bundle branch block on the electrocardiogram: The hea rhythm must originate above the ventricles (i.e., sinoatrial node, atria or atrioventricular node) to activate the conduction system at the correct point. The QRS duration must be more than 100 ms (incomplete block) or more than 120 ...
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Palivizumab is a monoclonal antibody used for the prevention of Respiratory syncytial virus
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.cyclodevelopmental form of life cycle is the one in which the disease agent undergoes only development but no multiplication.examples include mainly the life of microfilaria in mosquito. ref:park&;s textbook of preventive and social medicine,edition 22,pg no 94
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Clinical Features of datura * Dryness of mouth (dry as bone) * Bitter taste * Difficulty in talking * Dysphagia--- these are first noted * Dilated pupils * Diplopia * Difficulty in vision (blurring of vision, blind as bat) * Dry hot skin with flushing (red as beet) * Hyperpyrexia (hot as hare) * Drunken gait (ataxia) *...
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Poxviruses causing disease in humans Variola (small pox) Buffalopox Cowpox Vaccinia Monkeypox Molluscum contagiosum Tanapox
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Bile and the fluids found in the duodenum, jejunum, and ileum all have an electrolyte content similar to that of Ringer lactate. Saliva, gastric juice, and right colon fluids have high K+ and low Na + content. Pancreatic secretions are high in bicarbonate. It is impoant to consider these variations in electrolyte patte...
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Isoxazole derivative of 17 - alpha ethinyl testosterone propeies Causes atrophy of endometrium It is strictly antigonadotropin but acts as an androgen agonist Mode of action Acting on the hypothalamo - pituitary - gonadal axis - depression of frequency of GnRh pulses - suppression of pituitary FSH and LH surge. There i...
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Ans. is 'a' i.e., Inflammation of anal gland
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Tofacitinib : Janus kinases are intracellular enzymes that modulate immune cell activity in response to the binding of inflammatory mediators to the cellular membrane. Tofacitinib is an oral inhibitor of Janus kinases indicated for the treatment of moderate to severe RA in patients who have had an inadequate response. ...
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Splenomegaly, variceal bleeding in the absence of hepatomegaly suggest the diagnosis of non-cirrhotic portal fibrosis. Non-Cirrhotic Portal Fibrosis Its incidence is very high in India accounts for 15% to 18% of all patients with portal hypertension. Aetiology : Infection → It was suggested that E.coli can cause NCP...
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Mercury Poisoning Acute effect * By ingestion: local corrosive effects; nausea, vomiting, severe abdominal pain, chemical colitis, renal damage * By inhalation: chemical pneumonitis, pulmonary edema Chronic effect * Classic symptoms: tremor, gingivitis, erethism (greek erethismos = irritate) * Renal & CNS damage * Mina...
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Answer- A. Gas gangreneCrepitus in soft tissue is characteristic of gas gangrene.Edema, crepitus and brown exudate after injury suggest the diagnosis of gas gangrene.
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(B) 20-50 mg/dL CEREBROSPINAL FLUIDConstituentReference RangeSI UnitsConventional UnitsOsmolarity292-297 mmol/kg water292-297 mOsm/LElectrolytes * Sodium137-145 mmol/L137-145 meq/L* Potassium2.7-3.9 mmol/L2.7-3.9 meq/L* Calcium1.0-1.5 mmol/L2.1-3.0 meq/L* Magnesium1.0-1.2 mmol/L2.0-2.5 meq/L* Chloride116-122 mmol/L116-...
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Idiopathic juxtafoveolar retinal telangiectasis is characterized by abnormal retinal capillaries with variable intraretinal exudation after exclusion of an ocular or systemic cause. It was also termed as Idiopathic macular telengietasias. Group 1 unilateral juxtafoveal telangiectases represents a localized form of cong...
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The organisms which produce the pigment chiefly in the dark are called scotochromogens. M. scrofulaceum causes scrofula, a granulomatous cervical adenitis, usually in children. (M. tuberculosis also causes scrofula.) The organism enters through the oropharynx and infects the draining lymph nodes. Its natural habitat is...
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Ans. (c) Whipple's SurgeryRef: Bailey and Love 26th/e p. 1139* Whipple's Pancreaticoduodenectomy is the Surgical Treatment of Choice for Distal CBD cancer, Periampullary cancer and Pancreatic head cancer
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Refer Robbins page no Pg 8th/786 In medicine, the Sister Mary Joseph nodule or more commonly node, also called Sister Mary Joseph sign, refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen
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PoxvirusesGenusVirusPrimary HostDiseaseOhopoxvirus1. VariolaHumansSmallpox 2. VacciniaHumansFor smallpox vaccination3. CowpoxCowsRare in Humans4. MonkeypoxMonkeysRare in HumansMolluscipoxvirusMolluscum contagiosumHumansBenign skin nodulesParapoxvirus1. Orf2. Pseudocowpox3. Bovine papular stomatitisSheepCowsRare in Huma...
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Ans. is 'a' i.e., Erythema annulase cetrifugam Erythema annulare centrifugum : an asymptomatic or pruritic eruption of variable duration. The eruption may be associated with an underlying disease (eg, infection, malignancy, sarcoidosis, other systemic illness) The eruption begins as erythematous papules that spread per...
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B i.e. 200 - 300 mg
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Physiological jaundice: the peak serum bilirubin level does not exceed 15mg/dl.
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Amikacin is the second line antitubercular drug.Kanamycin, Amikacin and Capreomycin are more toxic antibiotics used as reserve drugs in rare cases not responding to the usual therapy, or infection by atypical mycobacteria. Any one of these is used at a time in combination with the commonly employed drugs to which resis...
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Ans. is 'a' i.e., Iliac lymph nodes Lymphatic drainage of uterus & cervix1) Cervix (lower lymphatics) Lymphatics drain into external iliac, internal iliac, and sacral nodes.2) Lower part of body (middle lymphatics) Lymphatics drain into the external iliac nodes.3) Fundus and upper part of body (upper lymphatics) Lympha...
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Section 304A in The Indian Penal Code Causing death by negligence: Whoever causes the death of any person by doing any rash or negligent act not amounting to culpable homicide, shall be punished with imprisonment of either description for a term which may extend to two years, or with fine, or with both. Ref - Krishnan ...
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Ans. is 'b' i.e., Sternocleidomastoid o Accessory nerve (eleventh cranial nerve) has two rootsy cranial and spinal.o Spinal accessory supplies :SternocleidomastoidTrapeziuso Follow ing are the 2 parts of the accessory nerve with their distribution:I Spinal part1 Sternocleidomastoid2. TrapeziusIICranial partMuscles of t...
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Morphine is not an inducing agent. Sevoflurane is the agent of choice and is used in N2O + O2 gas mixture. Halothane is the second choice inducing agent.
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A i.e. 3rd week
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Ans. B: Impaired bacteriolysis Chediak-Higashi syndrome is a rare autosomal recessive disorder that affects multiple systems of the body, and arises from a mutation in the lysosomal trafficking regulator gene, LYST. It is a disease with impaired bacteriolysis due to failure of phagolysosome formation. As a result of di...
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The rule of res ipsa loquitur means 'the thing or fact speaks for itself'. The rule is applied when the following conditions are satisfied: In the absence of negligence the injury would not have occurred ordinarily The doctor had exclusive control over the injury producing instrument or treatment The patient was not gu...
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Fimbriae Some gram negative bacilli carry hair like projections called fimbriae or pilli. Pilli are composed of antigenic pilin. They are unrelated to motility and are found on motile as well as nonmotile bacteria. Fimbriae function as organs of adhesion, helping the cells to adhere firmly to particles of various kin...
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Fetal fissure is closed by 6th week Failure to close can lead to formation of coloboma(eg- pear shaped coloboma of iris,chorioretinal coloboma i)
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Soft Tissue Sarcoma- Most common type of STS - Liposarcoma > Leiomyosarcoma- H/F type is site dependent- Extremity (MC site) - MFH (Malignant fibrous histiocytoma)- Retroperitoneum - liposarcoma- Viscera - GIST
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Ans. is 'a' i.e., Fenoldopam Summary And Recommendations for prevention of contrast induced nephropathy (uptodate recommendation )o Optimal therapy to prevent contrast-induced acute renal failure remains uncertain. Patients with near-normal renal function are at little risk and few precautions are necessary other than ...
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Paget's disease of bone (PDB) is a common condition characterised by focal areas of increased and disorgan ised bone remodelling. It mostly affects the axial skele ton, and bones that are commonly involved include the pelvis, femur, tibia, lumbar spine, skull and scapula. PATHOPHYSIOLOGY-Diseases of bone The primary ab...
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• Although IVU gives excellent images of the urinary tract, its use should be restricted because in a few patients the iodine in the contrast medium may provoke a potentially life-threatening anaphylactic reaction. • Patients with a history of allergy, atopy and eczema are particularly vulnerable, but severe reactions ...
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The child has Hanup's disease. This condition clinically resembles pellagra ("diarrhea, dementia, and dermatitis"), and may be misdiagnosed as this nutritional (niacin) deficiency. In fact, niacin therapy may actually be helpful in controlling the symptoms. The underlying problem is a defect in the epithelial transpo o...
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Acute myelogenous leukemia (AML) infiltrates the marrow and reduces normal hematopoiesis to account for anemia and marked thrombocytopenia. The initial presentation may be acute. The Auer rods are condensations of the azurophilic granules. Dohle bodies, which are patches of dilated endoplasmic reticulum, and toxic gran...
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