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Chances of scar rupture is less with an LSCS scar compared to classical scar ,inveed T shaped or T shaped incision. There is only 0.5% - 2% chance of rupture in LSCS compared to 4-8% chance in classical scar rupture. It is mainly due to better apposition and better healing of lower segment in puerperium compared to an ...
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Ans. D i.e. Complementary action of proteins A varied diet that includes different types of food will contain all the amino acids that an individual needs. If a food lacking in an amino acid is eaten with another food which contains it, then the second food compensates for the first and vice versa. This is called the c...
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Phenol and its derivatives acts by denaturing proteins, especially in cell membrane. It is active aginst gram positive bacteria but its activity is reduced in presence of organic matter. Glteraldehyde is considered a chemical sterilant since it has a broad spectrum of activity inluding being sporicidal. It acts by alky...
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C. Keratoderma mostly on glans
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B. i.e. (84 - IPC) (6.27 - Parikh 6th)* The law of insanity and criminal responsibility is embodied in section 84 IPC while section 85 and 86 deal with drunkenness and criminal responsibilityIMPORTANT - SECTIONS***Perjury (Giving false evidence)-191-IPC*Fabricating false evidence-192 IPC*Punishment for false evidence-1...
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Disequilibrium syndrome is caused by a rapid reduction in urea, sodium, and other solutes from the blood. This can lead to cerebral edema and increased intracranial pressure (ICP). Signs and symptoms include a headache, nausea, restlessness, vomiting, confusion, twitching, and seizures.
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Platelet dysfunction, measured by bleeding time, has been associated with a long list of drugs. Among nonsteroidal anti-inflammatory and analgesic medications, aspirin, indomethacin, phenylbutazone, acetaminophen, and phenacetin have been implicated, along with aminopyrine and codeine. Ibuprofen, however, has not. In a...
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Answer- B. Involves the whole skin along with subcutaneous tissue
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Ans. D. IF-4F(Ref: Harper 31/e page 399)43 S Preinitiation complex consist ofGTP-eIF2-tRNAi+ 40S subunit.This 43S Preinitiation complex is stabilised by eIF3 and eIF-1A.
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The magnitude of resting membrane potential from tissue to tissue ranges from - 9 to - 100.RMP of nerve Fibre is - 70mV(REF: TEXTBOOK OF MEDICAL PHYSIOLOGY GEETHA N 2 EDITION, PAGE NO 22)
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Hypehermic anhydrosis: Also called as desse syndrome After generalised profuse sweating for days perspiration stops suddenly in all pas of the body below neck region but persists in face and neck. Hyperkeratotic plugging of sweat glands. Papular rashes over face and neck.
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o PTEN is a tumor suppressor gene which is implicated in the causation of endometrial and prostate carcinoma.
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Abstract thinking REF: Kaplan & Sadock's Synopsis of Psychiatry 10' EditionPage 279; "Obsessions are persistent and recurrent idea, thought, or impulse that cannot be eliminated from consciousness by logic or reasoning; obsessions are involuntary and Ego-dystonic"Page 277Ego dystonia: Denotes aspects of a person's pers...
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Naltrexone is orally effective opiod antagonist useful in alcohol withdrawal. Acamprosate an NMDA receptor antagonist is useful in preventing relapse. Disulfiram is used to make alcohol consumption an unpleasant experience. It inhibit the enzyme aldehyde dehydrogenase. Ref: KD Tripathi 8th ed.
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CISTERNA CHYLI - This is an elongated lymphatic sac, about 5 to 7 cm long. It is situated in front of the first and second lumbar veebrae,immediately to the right of the abdominal aoa. It is overlapped by the right crus of the diaphragm. Its upper end is continuous with the thoracic duct. It is joined by the right and ...
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Ans. is 'd' i.e. Old age
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Papillary thyroid carcinoma It is the most common type of thyroid cancer. Carcinoma cells have nuclei which contain finely dispersed chromatin, which imparts optically clear or empty appearance, giving rise to the ground glass or Orphan Annie eye nuclei. Invagination of cytoplasm may give rise to the appearance of int...
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It is present in stomach soon after food. It establishes on body during labour and not after neonatal period. Lower respiratory tract ie below trachea is sterile.
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<p> kyasanur forest disease:- Agent- group B toga virus ( flavivirus). Rats and squirrels- main reservoir Monkeys- amplifier host. Vectors- Haemaphysalis. Age: 20-40 years. Sex- males more Mode of transmission- monkeys and ticks. By th bite of infective ticks. Incubation period- 3-8 days. {Reference: park&;s textbook o...
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Langerhans cell histiocytosis (LCH)*Langerhans cell is a dendritic cell which is an antigen presenting cell*LCH is a clonal histiocytic disorder*Birbeck granules are present in the cytoplasm of Langerhans cell.Characteristic features of LCHPresence of Birbeck granules - Electron microscopy ( Tennis racquet appearance)P...
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Thr changes occuring during the preeclampsia are thought to be tge consequences of vasospasam,endothelial dysfunction and ischemia. Refer page no 256 of Text book of obstetrics,sheila balakrishnan,2 nd edition.
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Answer is C (Enalapril) ACE inhibitors (Enalapril) are the agents of choice for treatment of hypeension in diabetic patients with proteinuria. Indication Treatment of choice Hypeensive patient with protenuriae ACE inhibitors or Angiolensin Blocker Hypeensive patient with Diabetese ACE inhibitors or Angiotensin Blocker ...
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The side chains of the acidic amino acids, aspaic acid and glutamic acid, are negatively charged above pH 3; in their ionized state, they are often referred to as aspaate and glutamate. Asparagine and glutamine are, respectively, the amides of aspaic acid and glutamic acid. Ref: Voet Fundamentals of Biochemistry 4th Ed...
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IgM is the first immunoglobulin to appear after exposure to an antigen. They are relatively sho lived hence their demonstration in the serum indicates recent infection. Normal level of IgM is 1.2mg/ml. It is also the earliest to be synthesized by fetus beginning by about 20 weeks of age. As it cannot cross the placenta...
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Mandibular Nerve Mandibular nerve is given at trigeminal ganglion at the floor of the middle cranial fossa and passes through the foramen ovale to enter the infratemporal region. It supplies 8 muscles developing in first pharyngeal arch: 2 tensors (tensor tympani and tensor palati), 3 elevators of mandible (MTM: Masse...
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Fuch's heterochromic iridocylitis is a chronic non-granulomatous uveitis. Sarcoidosis, TB and brucellosis cause granulomatous uveitis.
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The petromastoid part of the neonatal temporal hone encloses the internal ear, middle ear and mastoid antrum, all parts of which are full adult size at birth. But the mastoid process is absent and the stylomastoid foramen is near the lateral surface of the skull.
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The cephalic phase of gastric secretion occurs even before food enters the stomach, especially while it is being eaten. It results from the sight, smell, thought, or taste of food, and the greater the appetite, the more intense is the stimulation. Neurogenic signals that cause the cephalic phase of gastric secretion or...
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Air bronchogram Air bronchograms appear on a CXR whensomething other than air is present in the alveoli adjacent to a bronchus or bronchiole, making the air-filled bronchus more conspicuous than normal. That something is usually fluid, and this is most commonly due to pneumoniaalthough pulmonary oedema and haemorrhage ...
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Classic triad: Headache, Diaphoresis, Palpitations. Most common symptom is headache. MC manifestation is Hypeension.
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Papule: a circumscribed palpable elevation, less than 1 cm in diameter. The only distinction between a papule and a nodule is the size, and this is aificial; some lesions characteristically occur at the smaller size of a papule, whereas others typically enlarge from a papule to become a nodule. Nodules have a deeper co...
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Ans. A: DM Any condition that causes sensory or autonomic neuropathy can lead to a Charcot joint. Charcot ahropathy occurs as a complication of diabetes, syphilis, chronic alcoholism, leprosy, meningomyelocele, spinal cord injury, syringomyelia, renal dialysis, and congenital insensitivity to pain. Diabetes is consider...
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Ans. Bitter almond
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The main source of energy in the diet is carbohydrates derived largely from cereals and provide 50-80% of daily intake. Most families derive 10-12% of energy from proteins. Energy from fats may vary from 5-30%.Ref: Park; 23rd ed; Pg 634
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Osteopetrosis/ marble bone disease: * Bone within bone appearance on xray (increased bone density) * Due to mutation in CLCN7 gene. * Leads to defective bone resorption * C/F: Neurological problems present, Deafness, Macrocephaly , hepatosplenomegaly, Pancytopenia * Investigation: Low phosphorus and calcium levels with...
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Saddle block is the spinal anesthesia given in sitting position and the patient remains seated for 5 minutes. It is used for perianal surgeries.
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Approximately 25 % of childhood status epilepticus is idiopathic; 25% is associated with fever or meningoencephalitis; 50% of patients have a neurodevelopmental abnormality, head trauma, stroke, drug intoxication, subarachnoid bleed, pyridoxine deficiency, or metabolic abnormality ( hypoglycemia and hyponatremia ).Ref:...
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Other important factors affecting the composition of saliva are flow rate, differential gland contribution, circadian rhythm, duration of stimulus, nature of stimulus and diet. The concentration of constituents in saliva depends only on the rate of flow and not on the nature of stimulus.
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Gonioscopy: Owing to lack of transparency of corneoscleral junction and total internal reflection of light (emitted from angle structures) at the anterior surface of cornea it is not possible to visualize the angle of anterior chamber directly. Therefore, a device (goniolens) is used to dive the beam of light and this ...
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Ans. is 'c' i.e., a2A o Dexmedetomidine is a centrally active selective a2A agonist.o Has been explained in previous sessions.
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Lobular carcinomas have a greater incidence of bilaterality.
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X-rays are electromagnetic radiations with following properties: Velocity = 3 x 108 m/sec or 2 lakh miles/sec They cannot be focused, reflected or refracted. They cast the shadow of the objects falling in their path. They are affected by electric and magnetic field. Ref: Karjodkar 3rd Ed, Pg-72
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Answer is B (Unilateral hilar lymphadenopathy): Unilateral hilar lymphadenopathy as pa of the primary complex is a characteristic feature of primary tuberculosis Primary tuberculosis: It is the first infection with tubercle bacilli in individuals who have not been previously exposed to the organisms Seen in children Q ...
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Following structures are examined serially: Base of tongue, right and left valleculae, epiglottis, (its tip, lingual and laryngeal surfaces), right and left pyriform sinuses,aryepiglottic folds, arytenoids, postcricoid region, both false cords, anterior and posterior commissure, right and left ventricles, right and lef...
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Lungs
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Anterior cruciate ligament prevents posterior displacement of the femur on the tibia and hyperextension of the knee joint. When the joint is flexed at a right angle, the tibia cannot be pulled anteriorly because it is held by the ACL.**watch the wordings carefullyReference: Chaurasia; 6th edition
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p53 gene (TP53): Located on the short arm (p) of chromosome 17, p53 gene (also termed TP53 because of molecular weight of 53 KD for the protein) like pRB is inhibitory to cell cycle. However, p53 is normally present in very small amounts and accumulates only after DNA damage.  The two major functions of p53 in the norm...
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There is currently no data available regarding the use of sugammadex for the 'immediate reversal' of vecuronium. However, sugammadex is recommended for reversal of vecuronium once spontaneous T2 twitch has been achieved, using a dose of 4mg/kg to reverse 0.1mg/kg of vecuronium.Sugammadex is not effective against benzyl...
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Labour
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Ans. is 'a' i.e., Valproic acid
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Ans. (a) Large elastic vessel
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Acute management of a migraine with 5HT1agonist Rizatriptan and eletriptan are the most efficacious of the triptans currently available Triptans are selective 5-HT1B/1D receptor agonists. Sumatriptan used in acute conditions, not for chronic. Ref - Harrison's internal medicine 20e pg 3098
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Equivalence of antibody and antigen Precipitation reaction It is a type of antigen antibody reaction - When a soluble antigen combines with its antibody in the presence of electrolytes (NaCI) at a suitable temperature and pH, the antigen antibody complex forms an isoluble precipitate. . The amount of precipitate formed...
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Ans. 75 mm
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IVitamin K Function 1. Cataelyzes gamma-carboxylation of glutamic acid residues on various proteins concerned with blood clotting. 2. Catalyzes gamma-carboxylation of glutamic acid to GABA. Deficiency 1.Neonatal hemorrhage with increased PT and aPTT, but normal bleeding time. 2. Synthesized by intestinal flora, so vita...
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100000 sperms per oocyte is required for IVF.
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.It is a congenital diveiculum arising from the terminal ileum and is pa of the unobliterated proximal poion of the vitello intestinal duct. It is- * 2% common. * 2 feet from the ileo-caecal valve. * 2 inch in length. * It is congenital, results from incomplete closure of vitello-intestinal duct. * It is the most commo...
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(c) Source: (Wolff, p. 106)There are antibodies to skin basement membrane, but unlike pemphigus, antibody levels do not correlate with disease activity. Bullous pemphigoid is most common in the elderly, and the disease often starts with urticaria-like and pruritic erythematous lesions, before classic blisters occur. Th...
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Cultures are not used routinely but may on occasion prove positive in cases found negative by microscopy. Cultures permit the determination of zymodeme patterns for differentiation between pathogenic and nonpathogenic strains. TEXTBOOK OF MEDICAL PARASITOLOGY,CKJ PANIKER,6TH EDITION,PAGE NO 25
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The increase in the weight of the child with age- Age Weight (kg) Bih w 5 months 2w 1 year 3w 2 years 4w 3 years 5w
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Contraindications to use of diaphragm are: (i) prolapse, cystocele, rectocele because accurate fitting is not possible; (ii) recurrent infection and (iii) allergy to rubber or spermicidal agent. Reference: Shaw's Textbook of Gynaecology 16th edition page no 267
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Ans. C) Galactosemia Oil drop cataract Commonly seen in patients with galactosemia (a recessively inherited inborn error of carbohydrate metabolism). Accumulation of dulcitol (galactose reduction product) within the lens cells leads to increased intracellular osmotic pressure and fluid influx into the lens.
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(C) Arginine # Aminoacid can be acidic, basic or neutral depending up on their side chain.> The lower the Pka of the R gp, the more acidic will be the amino acids, so aminoacid with the highest Pka of the RGP will be most basic.Basic Amino AcidPka of 'R' group* Arginine12.5* Lysine10.8* Histidine6.0
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The larvae of S.srercoralis migrate through the lungs and they escape from the pulmanory capillaries into the alveoli leading to haemorrhages in the lung alveoli.Bronchopneumonia may also be present. (refer pgno:151 baveja 3 rd edition)
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When familial adenomatous polyposis result from mutations in the APC gene, it is inherited in an autosomal dominant pattern. Which means one copy of the altered gene in each cell is sufficient to cause this disorder. In most cases, an affected person has one parent with the condition. When familial adenomatous polyposi...
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.John Snow&;s map of cholera outbreaks from nineteenth century London changed how we saw a disease.John Snow who famously identified a pump as being the source of a cholera outbreak in 1854. Dr. Snow believed sewage dumped into the river or into cesspools near town wells could contaminate the water supply, leading to a...
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Hydrophobic or Nonpolar amino acids are present in transmembrane region. Hydrophillic or polar amino acids are present on outer surface of membrane. Leucine is a hydrophobic a.a. so it lies in transmembrane region.
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Ans. is 'c' i.e., Not affected by genetic affected
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The mesiodistal length of available bone in an edentulous area often is limited by adjacent teeth or implants. As a general rule the implant should be at least 1.5 mm from an adjacent tooth. This dimension not only allows surgical error but also compensates for the width of an implant or tooth defect, which is usually ...
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Ans. is'b'i.e., External oblique(Ref: BDC &/e Vol. II p. 212, 213; Ramesh Babu p. 219)Examinar is asking about superficial inguinal ring which is triangular defect in external oblique aponeurosis.Superficial inguinal ring is an anatomical structure in the anterior abdominal wall. It is a triangular shaped defect in the...
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Ans. is `d' i.e., Molindone Antipsychotics usually cause weight gain. Quitiapine, olanzapine, clozapine and resperidone, all have been implicated in weight gain. Molindone has often been repoed to cause weight loss rather than weight gain.
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Ans. is 'b' i.e., Increased P-oxidation o Starvation is characterized by decreased insulin : glucagon ratio.o This causesIncreased lipolysis - More FFAs for ketogenesis.Increased p-oxidation - Increased ketogenosis.Decreased oxaloacetate - Acetyl CoA is utilized in ketogenesis.Regulation of ketogenesiso Ketogenesis is ...
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* Jacobson=================lobotomy in chimpanzees * Almedia lima+ egaz moniz===PF leukotomy * Subcaudate tractotmy======OCD * Limbic leukotomy=========OCD and depression * Anterior capsulotomy Anterior cingulotomy Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 1065
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Large-needle (core needle) biopsy removes a core of tissue with a large cutting needle and is the diagnostic procedure of choice for both palpable and image-detected abnormalities. Core biopsy has the advantage that tumor markers, such as estrogen receptor (ER), progesterone receptor (PR) and HER2 overexpression can be...
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Ans. is 'a' i.e., Trichophyton o Dermatophytes are keratinophilic fungi, living only on the superficial dead keratin. That is why they infect skin, hair and nails. In skin they infect the most superficial layer of epidermis i.e., stratum corneum. They do not penetrate living tissues. Dermatophytes cause a variety of cl...
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Mechanism of action of sodium fluoride – When sodium fluoride solution is applied on the tooth surface as a topical agent, it reacts with the hydroxy apatite crystals in enamel to form calcium fluoride which is the main end  product of the reaction. As a thick layer of calcium fluoride gets formed, it interferes with t...
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Intravascular volume depletion in infants and young children commonly due to gastrointestinal diseases, pneumonia or meningitis. Impoant clinical features in estimating the degree of dehydration include, Capillary refill time Postural blood pressure Hea rate changes Dryness of the lips and mucous membranes Lack of tear...
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Ans. is 'a' i.e., Early relapsing syphilis . Chancre redux is the appearance of relapsing lesion at the site of the healed lesion, it is due to relapse of original infection (not due to reinfection). . Dead end infection is seen in Leptospirosis 4. Human Rabies 7. T. solium Legionella 5. Endemic typhus 8. Echinococcus ...
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To quantify the level of sedation and anaesthesia objectively, the intuitive solution is to monitor the brain directly. The "bispectoral index (BIS)" monitor is the first quantitative electroencephalographic index used in clinical practice to assess the depth of anaesthesia.
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Ans., Allergic conjunctivitis
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Kata thermometer: It's an alcohol thermometer Reading is from 100 F to 96 F Two instruments have used, the bulb of one is covered with wet muslin cloth called Wet Kata thermometer and the one without covering is Dry kata thermometer. Kata thermometer was initially designed for measurement of "cooling power" of air. now...
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The recommended level of fluoride in drinking water in the country is accepted as 0.5 to 0.8 mg/ Liter. -Park Maximum permissible limit is 1.5 mg/Lit.
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The patient would've sustained a cervical spine trauma after the fall. The 1st step in evaluating such patients is stabilize the cervical spine and spinal column backboard, cervical collar until a spinal injury is eliminated. The next step is to assess airway, patient is hypoxic and hypopneic requires emergency airway ...
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Ans. is 'b' i.e., Obtain anti HBs levels The child in question has received complete vaccination for Hepatitis B, is currently asymptomatic but has tested positive for HBsAg. The aim in avestigating the child fuher is to establish his immune status which can be best revealed by obtaining anti HBsAg levels. o If the tes...
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In RLN paralysis vocal cord is in adducted (median or paramedian) position.
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Teratomas are benign tumors composed of tissues derived from all three primary germ layers: ectoderm, mesoderm, and endoderm. They are most common in the ovary but also occur in the testis and extragonadal sites. Adenoma (choice A) is a benign tumor of epithelial origin. Chondroma (choice B) is a benign cailaginous tum...
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Propionyl CoA ↓ Succinyl CoA ↓ Succinate ↓ Fumarate ↓ Malate ↓ Oxaloacetate ⇒ GLUCONEOGENESIS Note: Acetyl CoA which is released from even chain fatty acids can't participate in gluconeogenesis Muscles lack glucose-6-phosphatase and hence can't.
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Ans is 'd' ie Pernicious anemia You, dont expect pernicious anemia to cause peptic ulcer. In pernicious anemia there is autoimmune destruction of the parietal cells leading to hypochlorhydria which fuher progresses to achlorhydria. ---, Etiology of Peptic Ulcer * Acute peptic Ulcer i) NSAIDS Ingestion ii) Stress - Cush...
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Carbamazepine is the drug of first choice for the treatment of complex paial seizures of children. These seizures sta focally and subsequently generalize with a loss of consciousness. Carbamazepine is an anticonvulsant drug which is chemically related to the tricyclic antidepressants. This drug has been shown to be eff...
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Ans. is 'b' i.e., Betadine (Ref: Ananthanarayan, 9th/e)Best skin disinfectant is Povidone iodine, Aqueous and alcohol based povidone iodine preparations are widely used in skin disinfection and skin preparation of the skin.Savlon and Dettol are more active against gram positive bacteria than gram negative bacteria.
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Ans. is 'b' i.e., Promethazine o We all know, blockade of D2 receptors in brain produce extrapyramidal side effects (as caused by antipsychotics), and acute muscular dystonia (dystonic reaction) is one of them. o Treatment of choice for acute muscular dystonia is central anticholinergic. o But, in given options, they h...
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Ans. Lateral decubitus view
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Vascular supply of biliary tract The Supra duodenal and infrahilar bile duct are Predominantly supplied by two axial vessels that run in a 3- and 9-'o clock position These vessels are derived from the superior pancreaticoduodenal, right hepatic, cystic, gastroduodenal and retro duodenal aeries It has been estimated tha...
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Ans. is 'c' i.e., Increased cardiac contractility Factors affecting cardiac outputo Cardiac output is the product of stroke volume and heart rate. Hence any factor which affects either the stroke volume or the heart rate or both affects the cardiac output.A) Factors affecting stroke volume# Stroke volume, which is the ...
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Staphylococcus infection - human patients and carriers are the commonest sources of infection. About 10- 30% healthy person carry bacterial in the nose, skin, axilla, perineum and throat. Ref: Textbook of microbiology; Ananthanarayan and paniker's 10th edition; Pg:205
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Cocaine inhibits the neuronal membrane transpoers for catecholamines, thereby potentiating the effect of NE at adrenergic receptors in the vasculature, resulting in vasoconstriction and reduced cocaine absorption in vascular beds where adrenergic effects predominate. Ropivacaine and bupivacaine also cause vasoconstrict...
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B cell associated markers are CD 10,CD19,CD20,CD21,CD22 and CD23. CD 135 is a proto oncogene.it is also the receptor for the cytokine Flt3 ligand and has the presence of tyrosine kinase activity.its mutation can lead to acute myelogenous leukemia and is associatedwith a poor prognosis.(ref Robbins 9/e590,8th /600)
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parks textbook of preventive and social medicine 23rd edition. *among the commonly used nuts ,cashewnut and almonds are good source of iron,but pistachio is the richest containing 14mg of iron per 100g .
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Mallory-Weiss Tear A Mallory-Weiss tear is a linear mucosal rent near or across the gastroesophageal junction. It may disrupts the submucosal aeriole resulting in brisk hemorrhage. MUST KNOW: Endoscopy is the best method of diagnosis. Actively bleeding tear can be treated endoscopically with epinephrine injection, coap...
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Methods of delivery of after coming head of breech : Burns-Marshall technique Mauriceau Smellie Viet technique Piper's forceps Ref: Datta Obs 9e pg 360.
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