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61,552 | [The hydrodynamic mucosa-cytology by means of ultrastructures filters in upper respiratory tract and oesophagus]. | A rinse-and-suck-sound is presented, which conveys cytological material to a special filter mechanism. The heart of the system is a well-known filter, an electric pump, and a new constructed vacuum chamber. After Papanicolaou staining the filters are being cleared and allow a light-microscopical judgement. A reduction ... |
61,558 | Multiple sclerosis cerebrospinal fluid produces myelin lesions in tadpole optic nerves. | To investigate the myelinotoxicity of cerebropsinal fluid in multiple sclerosis, we used an in vivo model of the myelinated central-nervous-system tract of tadpoles for quantitative double-blind tests of 46 cerebrospinal-fluid samples. Groups of xenopus tadpoles were injected with cerebrospinal fluid near the optic ner... |
61,560 | Need for alpha-fetoprotein assays. | An alpha fetoprotein assay is useful in diagnosing open neural-tube defects. The U.S. Food and Drug Administration is urged to establish guidelines for reagent licensing so that this test can be available throughout the country. Correct data for fetuses of 15-16 weeks' gestation are now complete. With this data and ... |
61,564 | Urinary excretion of beta2 microglobulin after the induction of a diuresis. A study in healthy subjects. | An increased diuresis was induced in each of four healthy subjects by intravenous infusion of urea, saline and sodium bicarbonate and by an oral water load. The excretion of a low molecular weight protein (LMW-protein), beta2-Microglobulin (beta2mu), was determined by a radioimmunoassay, the urinary concentrations of t... |
61,568 | [28 cases of malabsorption syndromes with villopathy]. | A personal series of 28 cases of malabsorption with villopathy (22 Gee, 1 Whipple, 1 alpha-chain, 1 hypogammaglobulinaemia, 3 not yet diagnosed) is presented. The response to a gluten-free diet is the essential clue to diagnosis. Where sensitivity is not found, diagnosis becomes difficult and requires careful immunolog... |
61,570 | Oral cytologic patterns in relation to smoking habits. Some epithelial, microfloral, and leukocytic characteristics. | Papanicolaou smears from the cheeks and tongues of 790 alcoholic patients were evaluted for possible associations between cytologic features and cigarette consumption. The findings appear consonant with the view that microscopic changes are frequent in clinically unremarkable areas of the mouth and that tobacco induces... |
61,579 | [Detection and prognostic significance of Ag "e" and its antibody in the course of HB virus infections[]. | A new antigen antibody system the e Ag and Ab has been investigated by immunodiffusion and counterelectrophoresis in the serum of 509 subjects. Those included 242 patients with polyarteritis, acute chronic or fulminant hepatitis; 85 hemodialysis HBs Ag carriers and 182 asymptomatic HBs Ag carrier blood donors. Neither ... |
61,580 | Nucleotide sequence from the coding region of rabbit beta-globin messenger RNA. | A sequence of 89 nucleotides from rabbit beta-globin mRNA has been determined and is shown to code for residues 107 to 137 of the beta-globin protein. In addition, a sequence heterogeneity has been identified within this 89 nucleotide long sequence which corresponds to a known polymorphic variant of rabbit beta-globin.... |
61,581 | Influence of phosphate on activity and stability of reverse transcriptase from avian myeloblastosis virus. | Activity of RNA-dependent DNA polymerase (RDDP) from avian myeloblastosis virus (AMV), either in purified form or in virus lysates, was increased by phosphorylation. Stability of RDDP in lysates buffered with phosphate was much greater (no loss of activity in 48 hours at 4 degrees) than that in lysates buffered with Tr... |
61,582 | Field testing the nursing quality monitoring methodology: phase II. | The design, analysis, and findings of a field test of a methodology for monitoring quality of nursing care are presented. Quality care scores for types of patients (self-care, partial care, complete care, intensive care), types of units (medical, surgical, medical-surgical, pediatric, and intensive care), and shifts (d... |
61,585 | Propranolol in the treatment of thyrotoxicosis: a review. | The clinical manifestations of hyperthyroidism have suggested to physicians for many years that the sympathetic nervous system may be involved in their production. Despite this, the precise interrelationship between the thyroid gland and the sympathetic nervous system has never been defined but controlled investigation... |
61,587 | An RNA-dependent DNA polymerase, different from the known viral reverse transcriptases, in the chicken system. | The properties of an RNA-dependent DNA polymerase (an RNA-dependent DNA nucleotidyltransferase), which occurs ubiquitously in the allantoic fluid of uninfected, leukosis-virus-free eggs, are described. It is shown that the enzyme can synthesize faithful transcripts from natural RNA (globin mRNA). By biochemical and imm... |
61,588 | A general method for cloning eukaryotic structural gene sequences. | Complementary DNA, transcribed in vitro from purified rabbit globin messenger RNA and made double-stranded, has been inserted into Escherichia coli plasmids pSC101 and pMB9 by the poly(dT)/poly(dA) "tailing" and annealing technique. E. coli transformants given by this DNA preparation have been shown to contain globin s... |
61,589 | Antigenic relationships among five reovirus-like (RVL) agents by complement fixation (CF) and development of new substitute CF antigens for the human RVL agent of infantile gastroenteritis. | The human reovirus-like (HRVL) agent, Nebraska calf diarrhea virus (NCDV), epizootic diarrhea of infant mice (EDIM) virus, simian agent (SA)-11, and the "O" (offal) agent were found to be similar, if not identical, in reciprocal complement fixation (CF) tests employing hyperimmune animal sera. In addition, in CF tests ... |
61,590 | Stability of Rauscher leukemia virus under certain laboratory conditions. | The stability of Rauscher leukemia virus (RLV) was investigated under certain laboratory conditions. The half life of the virus at 37 degrees was 7 hr, and considerably longer at lower temperatures. RNA dependent DNA polymerase activity was more stable than infectivity at all temperatures. Air dried virus had a half li... |
61,594 | Thyroxine-binding proteins. | As is the case for most small molecules in the body, the thyroid hormones are involved in interaction with proteins. The present discussion has centered on the hormone-protein interactions which occur in plasma. Although some of this is with proteins which also engage in other binding reactions, at least one protein, T... |
61,596 | Effects of antacids on gastrointestinal absorption of drugs. | Antacids interfere with gastrointestinal drug absorption by either increasing or decreasing the rate at which a drug is absorbed, or the total quantity absorbed. Antacids influence drug absorption by alteration of ionization state or solubility, factors dependent upon pH. Antacids also delay gastric emptying and are ca... |
61,606 | [Programmed typing in a school for the physically handicapped - testing a new audiovisual learning system (author's transl)]. | Within the framework of a test performed at a school for the physically handicapped, 10 pupils with disabilities varying in type and degree of severity completed a typing programme which was adapted to their individual physiological possibilities. The deliberate use of audiovisual media contributed both to an adaptatio... |
61,608 | [Acquired B antigen]. | Many cases of acquired B antigens, always observed in group A subjects have been so far reported. Most of them were found in patients with digestive tract disease, essentially colonic cancer. An investigation on 200 patients in a gastroenterology department showed that this B-like antigen was quite frequent (10,6%); it... |
61,609 | [The biochemical aspects of blood group antigens]. | The biochemical aspects of the immunodominant structures of blood groups antigens are mainly restricted to the following: ABH and Lewis in secretory fluids or on the red blood cells; P system (P1, P, Pk antigens); MN antigens and related; Tn and Tn antigens; Some hypothesis may be put forward for the I, i antigens. Man... |
61,610 | [Quantitative and thermodynamic study of weak A erythrocyte phenotypes]. | The analysis of more than 140 "weak A" samples: A3, Ax, Aend, Am, Ay and Ael, support the classical distinction between each subgroup which has been established on serological and genetical data. Accordingly, a valuable classification of these rare phenotypes must take into account, (i) the mode of inheritance, (ii) th... |
61,611 | [Heterogeneity of the cellular distribution of erythrocytic A antigens. Ultramicroscopic study]. | A and A1 antigens have been detected on cells of the human erythrocyte series by immunoelectron microscopy. These antigens have been revealed by an indirect method involving various anti-A and anti-A1 antibodies (allo, auto, hetero-antibodies) and peroxidase-conjugated anti-immunoglobulin antibodies. Immunologic labell... |
61,612 | [Proposed practical classification of weak B phenotypes B 3, Bx, B el]. | Although the first weak B phenotypes have been observed some thirty years ago, very few comparative studies have been done until now. In this work, different samples were analysed, using immunogenetic methods, thermodynamics, agglutination kinetics and agglutination profiles. Almost hundred weak B samples were tested, ... |
61,616 | [Residues of chlororganic and phosphorganic phitodrugs in samples of honey produced in Emilia-Romagna (author's transl)]. | Forty-five samples of honey produced in Emilia-Romagna between June and September 1974 have been subjected to gaschromatography to check for the presence of residues of chlororganic and phosphorganic phytodrugs. Residues of chlororganic phytodrugs in appreciable amounts have been found to be present in 11 samples only,... |
61,622 | Early diagnosis of virus-caused vesicular rashes by immunofluorescence on skin biopsies. II. Poxvirus (vaccinia). | Immunofluorescence (IF) was used to demonstrate vaccinia virus antigen in frozen sections of skin biopsies from the site of revaccination in 42 individuals. The immunoglobulin (Ig) of a rabbit anti-vaccinia serum and the Ig of the pre-immune serum conjugated with fluorescein-isothiocyanate (FITC) was employed. 11/13 bi... |
61,623 | Tourist hepatitis and gamma globulin prophylaxis. | Millions of tourists from Northern Europe visit the Mediterranean basin each year. Some of them provide themselves with gamma globulin prophylaxis against hepatitis A before departure. In Sweden about 50% of these travellers receive prophylaxis which means that about half a million Swedish tourists are injected with ga... |
61,627 | Lymphocytes and specificity of eosinophilia. | Repeated injections of soluble antigen derived from the body fluid of Ascaris lumbricoides induced a substantial accumulation of eosinophils in the peritoneal fluid of mice. Evidence of an underlying immune mechanism was sought. A single injection of antigen was ineffective in eliciting eosinophilia, but it primed reci... |
61,631 | The effect of antithrombin III on the activity of the coagulation factors VII, IX and X. | Antithrombin III, purified to homogeneity according to polyacrylamide gel disc electrophoresis and immunoelectrophoresis, inhibited the activity of purified factor IXa and Xa, whereas factor VII was not inhibited either in the active or in the native form. Antithrombin III is the single most important inhibitor of fact... |
61,633 | Fertility trends: 1950-75. | During the past 25 years, the world's population increased by 60 percent to 4 billion people. The period witnessed a momentous decline in mortality, which will probably continue in the developed countries. Fertility has fallen dramatically in the developed countries to quite low levels. In the developing countries, whe... |
61,634 | Effect of organ culture on the survival of thyroid allografts in mice. | Mouse thyroid can be maintained in organ culture for 4 weeks. Uncultured BALB/c thyroid is rejected 10-15 days after transplantation under the kidney capsule of H-2 disparate recipients (C57BL, CBA). Organ culture of thyroid tissue prior to transplantation prolongs allograft survival. This prolongation of graft surviva... |
61,635 | Immunological enhancement of rat renal allografts using rabbit antisera with specificity for rat transplantation antigens. | Rabbits immunized with particulate and soluble preparations of rat lymphoid tissue of the HO strain produced antisera which reacted without strain specificity on rat lymphocytes. Absorption of the sera with tissue from the AS strain of rat removed the antibodies reacting with AS tissue leaving activity against HO cells... |
61,637 | [The distribution of isoenzymes of lactate dehydrogenase in benign and malignant neoplasms of the human prostate (author's transl)]. | The distribution of LDH isoenzymes from homogenate supernatant of bioptically obtained benign and malignant tumours of the human prostate was investigated by agar gel electrophoresis and correlated with the degree of histological differentiation of these tumours. In comparison to the benign adenomas (52.6% H subunits),... |
61,632 | The ophthalmic toxicology of dichlorøomethane. | The toxic hazard to the eye from dichloromethane (DCM) as liquid or vapour has been assessed rabbits. 0.1 ml DCM caused inflammation of the conjunctiva and eyelids persisting for up to 2 weeks; keratitis and iritis occurred in two-thirds of the animals. Corneal thickness, measured in vivo, increased by a maximum of 59%... |
61,639 | Role of radiation therapy in cancer of bladder. | The results of treating 50 patients with bladder cancer with radiotherapy over a three-year period are evaluated. Ten cases (20 per cent) were treated for palliation. Sixteen of 40 patients treated with intent of cure are considered well with no evidence of disease. Six additional cases were salvaged by further surgery... |
61,645 | [Biogenic amine metabolism in homeotherms exposed to pesticides of different chemical nature]. | Some aspects of the biogenic amines -- serotonin and histamine metabolism in rats and guinea pigs following introduction to them of pesticides of different chemical nature, viz. gamma-isomer of hexachlorcyclohexane (lindane) and dimethyldithiocarbamate zinc (zyram) were studied. These pesticides were found to dissimila... |
61,648 | [Serum immunoglobulin E level in bronchial asthma]. | Serum immunoglobulin E level was determined in 50 patients with bronchial asthma, treated in the out-patients department and clinical conditions at the Faculty Hospital--Varna. The quantitative determination of immunoglobulin E was carried out by radial immunodiffusion according to Mancini with monospecific anti-IgE gl... |
61,647 | [Immunological studies of patients with chronic ulcerative-hemorrhagic colitis]. | Immunologic investigations were carried out with 22 patients with chornic ulcerohemorrhagic colitis in the course of three years. The average values of IgA and TSRFC in the active stage of the disease surpass significantly the normal values. They, to a very large degree, can contribute to the assessment of an advancing... |
61,657 | Alpha-fetoprotein and liver cell proliferation in rats fed choline-deficient diet. | Liver 3H-thymidine labelling index and serum AFP were determined in rats fed a standard laboratory or choline deficient diet. A significant increase in the rate of liver cell proliferation was evidenced in animals on the deficient diet. Furthermore, elevated serum AFP levels were detected in a proportion of these rats.... |
61,660 | [Differential-diagnostic and prognostic significance of antinuclear factors]. | On the patients of the consulting point for rheumatic diseases of the policlinical institute of the Karl-Marx-University Leipzig analytic examinations of the course for the existence of the LE-cell factor were carried out. We used the loose-body-test after van Soeren as screening test, controlled positive test results ... |
61,661 | [Ways and possibilities in the diagnosis of leukemic diseases]. | Malign diseases and thus also leucoses are pathogenetically as well as therapeutically an up to now unsolved problem. Since according to the modern standard of our knowledge a chance of healing at best is to be found in the recognition of the pre-stages and the early stages, therefore, intensive diagnostic efforts are ... |
61,664 | [Antiarrhythmic effect of disopyramide in ventricular extrasystole and auricular fibrillation]. | Disopyramide (B 712) was tested in 39 patients with chronic arrhythmias of different kind: 23 cases with atrial fibrillation, 16 cases with ventricular ectopic beats, two cases with supraventricular tachycardias. The effect of disopyramide was compared to a pretreatment with one or several antiarrhythmic drugs (quinidi... |
61,666 | [Protective measures, tolerance margins and legislation]. | Federal, cantonal and communal legislation in Switzerland suffers from incompleteness and other deficiencies in spite of a multitude of regulations concerning air management. The future legislation on environment will have to fill in the gaps as far as possible and to eliminate these deficiencies. The legislation in pr... |
61,668 | [Modification of the thrombocyte function using hormonal contraception. 1. Thrombocyte count, thrombocyte propagation and platelet aggregation under hormonal contraception]. | The number of platelets, spreading and aggregation of platelets in plasma of 102 women treated with Ovosiston, an anticonceptive agent, were investigated. A significant increase of the number of platelets, spreading and aggregation of platelets was observed. Conclusions from isolated observations are not possible. |
61,669 | [Modification of the thrombocyte function using hormonal contraception. 2. Platelet adhesiveness, thromboelastography, conclusions]. | Platelet adhesiviness and thrombelastographic investigations in plasma by 102 women treated with Ovosiston, an anticonceptive agent were observed. A significant increase of adhesiveness and thrombelastographic variations was found. In conclusion showed abnormalities of platelet functions and thrombelastographic values ... |
61,667 | [Air pollution in Switzerland--sources and extent]. | The immediate source of air pollution is the fuel consumption that goes on in domestic heating (about 50%), in motor vehicles (about 25%), and in industry (about 25%). Immissions in towns and agglomerations do not only depend on the number and size of these issuing sources but also on the location and meteorological co... |
61,689 | Acquired resistance to parathyroid hormone. | Studies are presented in a patient with pseudohypoparathyroidism who showed a partial response to parathyroid extract. Resistance to the extract was observed after its short-term administration for the gourth time. Serum from the patient contained antibodies of the gamma G globulin class which bound 125I-labelled bovin... |
61,691 | On the cytochemical demonstration of basic proteins in the cell nucleus, including the nucleolus. | A combined Feulgen-alkaline fast green method is described for simultaneous demonstration of DNA and basic proteins in the cell nucleus. The method is based on preserving both types of substances in the tissue section and releasing in them reactive groups for the 2 kinds of staining. These conditions are best provided,... |
61,692 | Electron microscopic demonstration of hyaluronidase sensible proteoglycans at the presynaptic area in mouse cerebellar cortex. | By application of electron cytochemical techniques to cerebellar tissue, the presence of proteoglycans was demonstrated at the axoplasmic matrix of mossy fiber endings. Blocks of glutaraldehyde (G) fixed mouse cerebellum were processed according to the following procedures: a) Some pieces of tissue were post-fixed in o... |
61,693 | Recent progress in the staining of DNA-aldehyde in cell nuclei. | The paper is a review of studies on Feulgen staining of nuclear DNA. For convenience, the paper is split into several sections, such as (a) the characteristic of the dyes used for the manufacture of Schiff reagent (b) preparations of Schiff reagent (c) fixation of the material (d) hydrolysis (e) staining with Schiff re... |
61,694 | Immunological properties of dialysis retentates from penicillin. | Retentates from benzylpenicillin preparations marketed in Canada were used in immunological studies in order to determine if they were immunogenic in experimental animals with respect to anaphylactic antibody production. The retentates obtained consisted mainly of penicillin polymers. Impurities of protein nature were ... |
61,690 | CEA and CEA-like activity in gastric cancer. | CEA activity was studied using a three-layer bridge immunoperoxidase method in paraffin-embedded histological sections of gastric mucosa from patients with gastric cancer and from normal asymptomatic subjects. In all cases gastric cancer cells showed CEA or CEA-like activity irrespective of the histological type of can... |
61,695 | The origin of serum protein, A, B, and H blood group, and Gm and Inv antigens in house dust. | Materials precipitated from an aqueous extract of house dust by saturation with ammonium sulphate showed immunological reaction with antisera to human serum albumin, human alpha1-acid glycoprotein, human IgG, Gm and Inv antigens and to A, B and H antigens. It is concluded that the albumin and alpha1-acid glycoprotein a... |
61,696 | Neurohistological and histochemical observations on the lung of Francolinus pondicerianus (gray partridge or safed teeter) as revealed by the cholinesterase technique. | An investigation was undertaken to demonstrate the neural elements of the lung of Francolinus pondicerianus, from the point of view of neurohistology and histochemistry. The staining of the neural elements was done by the cholinesterase technique with a maintained pH of 5.2, temperature 40 degrees C and incubation peri... |
61,697 | Ultrastructural study on the meiotic prophase nucleus of rat oocytes. | Rat oocytes in the meiotic prophase are studied by means of classical techniques of electron microscopy, preferential staining methods for DNA and RNA and specific enzymatic hydrolysis. The axial cores in leptotene and the lateral arms in the pachytene synaptonemal complex are composed by fibrils that keep a positive c... |
61,698 | Whipple's disease of the central nervous system. | Whipple's disease presenting as a neurological disease without gastrointestinal symptoms is an unusual occurrence. A 40 year old man suffered hypersomnia, memory loss and progressive ophthalmoplegia for 6 months prior to death. The nature of this disease was not established during life. Extensive granulomatous inflamma... |
61,699 | Effects of trans-clomiphene in combination with AY-9944 on rat CNS morphology and biochemistry. | Developing rats were injected intraperitoneally twice weekly with a combination of two hypocholesterolemic agents: trans-clomiphene 50 mg per kg body weight, and AY-9944, 5 mg per kg body weight. Treatment was initiated at 5 days of age. Biochemical and electron microscopic examination was carried out on animals sacrif... |
61,700 | Alpha-fetoprotein in amniotic fluid and serum from pregnant women with severe rhesus isoimmunization. | In 12 pregnant women with severe rhesusiso-immunization the AFP concentration in amniotic fluid (50 samples), maternal serum (212 samples) and cord blood (5 samples) were determined by immuno-electrophoresis. With surviving infants (9 patients) the initial values in amniotic fluid before intrauterine transfusion (IUT) ... |
61,701 | Induction of the "pregnancy zone" protein by conjugated oestrogens. | Treatment with conjugated oestrogens was found to increase significantly the serum concentration of the pregnancy zone protein (PZ) in a group of postmenopausal women. The basic level of PZ before treatment was comparatively high in this group of women and might be related to age and previous pregnancies. Naturally occ... |
61,702 | HCT and thyroid function in molar pregnancy. | HCT, TSH, T3, T4, PBI, T3-RSU, TBG binding capacity, BMR and thyroid uptake of radioiodine were measured simultaneously on the volunteers with hydatidiform mole and normal pregnancy. TRH stimulation tests were performed on the two groups. The serum HCT levels were higher in association with molar pregnancy than in norm... |
61,705 | Identification of antigens within the so-called vaccinia L-S complex by means of quantitative immunoelectrophoresis. | The so-called L-S antigen complex of vaccinia virus antigens was studied using gel diffusion and various immunoelectrophoresis methods. The low resolution power of the gel diffusion method and the inconsistency of the results obtained rendered this method unsuitable for identification of individual antigens and for com... |
61,706 | The effect of specific antibodies on the inhibition of leucocyte migration caused by staphylococcal peptidoglycan. | Specific antibodies to the various antigenic determinants of staphylococcal peptidoglycan are tested for neutralization of the inhibiting effect of peptidoglycan on leucocyte migration. Antibodies to the C-terminal D-Ala-D-Ala group of pentapeptides and to the C-terminal of the glycine bridge showed high neutralizing e... |
61,708 | Diffusion of sodium in axoplasm of myelinated nerve fibre. Potential clamp analysis. | The diffusion of sodium and lithium in the axoplasm of myelinated fibres of Xenopus laevis was investigated. The sodium current associated with pulse steps was measured and the internal sodium concentration was calculated from these measurements with the constant field equation. The internal sodium concentration was in... |
61,709 | Ionic composition and cardiotoxicity of dimeric contrast media at injection into the coronary arteries of rabbits. | The relation between ionic composition and cardiotoxicity of two dimers, iocarmate and iozomate, was investigated by selective injection into the left and right coronary arteries, Least toxic reactions developed at a sodium concentration of 263 to 315 mmol/l for sodium-meglumine iocarmate and 271 to 379 mmol/l for sodi... |
61,710 | Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum. | The root and stem decoctions of Sinomenium acutum Rehd. et Wils. (formerly Sinomenium diversifolius Diels, one type of Fang-chi (Chinese)) have been used as a folk remedy for neuralgia and rheumatoid arthritis in many areas of the Far East. In Japan and China various viny plants have been identified as Fang-chi (Boi in... |
61,711 | Rapid determination of thyroxine binding proteins of human serum. | A simple method is described for determing thyroxine binding proteins in human serum by electrophoresis at pH 8.6, using cellulose acetate membrane as the supporting medium. The procedure had high reliability in sera of normal subjects, pregnant women and patients with decreased thyroxine binding capacity of thyroxine ... |
61,712 | Immunological cross reactivity of four enzymes involved in the biosynthetic pathway of lysine, methionine and threonine in Escherichia coli K12. | In Escherichia coli K12 the biosynthetic pathway of lysine, methionine and threonine is characterized by three isofunctional aspartokinases and two homoserine dehydrogenases. A single polypeptide chain carries the threonine-sensitive aspartokinase and homoserine dehydrogenase (AK I-HDH I), and a different polypeptide c... |
61,713 | Immunochemical examination of soluble antigens in the serum of Balb/c mice infected with Rauscher leukaemia virus. | The serum of Balb/c mice infected with Rauscher leukaemia virus contained soluble antigens characterized by alpha2 and beta globulin electrophoretic mobility; their respective molecular weights, as determined with gel filtration, were 40 000 and 120 000. The antigens differed in specificity and their corresponding dete... |
61,715 | Effects of midodrine, ST 1059, methoxamine and glycine on spontaneously beating guinea-pig atria. | The chronotropic effects of midodrine, glycine (10(-8) to 3.10(-3) M), ST1059 and methoxamine (10(-8) to 10(-3) M) were investigated in the spontaneously beating guinea-pig right atrial preparation. Midodrine and glycine produced a slight, but significant rise in atrial rate over a wide concentration range. The midodri... |
61,717 | Preparing and staining of Coxiella burnetii natural phase II antigen for the microagglutination reaction. | An improved method of preparing Coxiella burnetii natural phase II antigen of high purity enabled its staining for use in the microagglutination reaction (MAR). The antigen was as specific and sensitive for detection of phase II antibodies as the artificial phase II C. burnetii antigen prepared by periodate treatment f... |
61,718 | A method for serological differentation of closely related poxviruses. | A two-step gel precipitation reaction with antiserum to vaccinia virus, based on sequential addition of two test viruses was elaborated for differentiation of closely related orthopoxviruses. The appearance of an additional precipitation line indicated differences in the antigenic structure of the viruses compared. Dif... |
61,719 | Interspecies interactions of arboviruses. I. Competition phenomenon in mixed populations of Japanese encephalitis and West Nile viruses. | Two phenomena, competition and independent reproduction, were observed on co-cultivation of Japanese encephalitis (JE) and West Nile (WN) viruses in permissive systems. Competition occurred in populations propagated in mouse brains and led to elimination of JE virus. Only clones of WN virus were isolated from these pop... |
61,720 | Detection by immunofluorescence of avian myeloblastosis virus reverse transcriptase. | Peripheral blood cells of avian myeloblastosis virus (AMV-(infected chickens were examined at various intervals post infection by immunofluorescence. AMV revertase was identified in pro- and myeloblasts; it was localized mainly in the perinuclear zone or throughout the cytoplasm. No revertase was found in erythrocytes ... |
61,723 | Mustard operation and creation of ventricular septal defect in two patients with transposition of the great arteries, intact ventricular septum and pulmonary vascular disease. | The condition of patients with transposition of the great arteries, intact ventricular septum and severe pulmonary vascular disease is inoperable with present techniques. In a series of 260 surgically treated patients with transposition of the great arteries and intact ventricular spetum, 5 had severely increased pulmo... |
61,724 | Significance of anti-HBc in patients with hepatic disease. A comparative immunohistochemical study of blood and hepatic tissue. | Use of the immunofluorescent technic to examine liver sections disclosed different staining patterns for HBsAg and anti-HBc. In reverse, anti-HBc in serum can be detected by immunofluorescence using HBc-positive liver sections as substrate. In 57 of 89 sera tested, anti-HBc could be observed using immunofluorescence. O... |
61,725 | Nucleoprotein-coated latex particles in the serologic diagnosis of systemic lupus erythematosus. A comparative clinical and serologic study. | A commercially available test for systemic lupus erythematosus employing nucleoprotein-coated latex particles has been evaluated both clinically and serologically. The sera from all 40 subjects with active SLE had positive latex tests, while all 28 sera from healthy adults had negative latex tests. False-positive latex... |
61,727 | An evaluation of elastic tissue staining. | The Special Procedures Laboratory of the Department of Pathology at M.D. Anderson Hospital was concerned with the nationwide shortage of hematoxylin. The amount of this dye required for various staining solutions was calculated to determine thrifty usage. Some solutions required more hematoxylin than was available and ... |
61,728 | Experimental papilledema produced by cyclocryotherapy. | Cyclocryotherapy was a reliable method of producing prolonged decreased intraocular pressure and papilledema in the rhesus monkey. Histologic changes in papilledema caused by decreased pressure were indistinguishable from those in papilledema from increased intracranial pressure. Electron microscopic observations in pa... |
61,730 | The role of radiotherapy in the definitive management of rectal carcinoma. | The role of radiotherapy in the management of rectal and rectosigmoid cancer is still far from clear. Our experience with 98 patients is presented: eight patients were treated with radical radiotherapy, 13 received postoperative radiation, and 67 were treated for palliative purposes only (bleeding, pain, mass, and fist... |
61,729 | Immunofluorescent staining of the surfaces of lymphocytes in suspension from patients with dengue hemorrhagic fever. | Immunofluorescent staining of lymphocytes suspensions from 55 of 62 patients with dengue hemorrhagic fever was positive for dengue antigen and human beta1C/a-globulin on the surface, from the second ay before shock or subsidence of fever. The percentages of positive staining of both components gradually increased to a ... |
61,732 | Bleomycin, adriamycin, cyclophosphamide, vincristine, and prednisone (BACOP) combination chemotherapy in the treatment of advanced diffuse histiocytic lymphoma. | A new combination chemotherapy program for patients with diffuse histiocytic and mixed histiocytic-lymphocytic lymphoma was designed to prevent tumor recurrence during the recovery period of each treatment cycle. A myelosuppressive phase consisting of adriamycin, cyclophosphamide, and vincristine was followed by the no... |
61,735 | Observations on bacteriophages of Clostridium botulinum type C isolates from different sources and the role of certain phages in toxigenicity. | Twenty strains of Clostridium botulinum type C, including 12 isolates from avian sources with varying toxigenic properties, were examined by electron microscope for the presence of bacteriophages. All toxigenic strains were infected with one or two types of phages. Three types of phages designated large, small, and int... |
61,736 | Detection of Thiobacillus ferrooxidans in acid mine environments by indirect fluorescent antibody staining. | An indirect fluorescent antibody (FA) staining technique was developed for the rapid detection of Thiobacillus ferrooxidans. The specificity of the FA stain for T. ferrooxidans was demonstrated with both laboratory and environmental samples. Coal refuse examined by scanning electron microscopy exhibited a rough, porous... |
61,737 | Anterior and posterior groups of portal vessels in the avian pituitary: incidence in forty nine species. | The hypophyseal portal vessels were studied in forty nine species of birds. The primary capillary plexus in the median eminence is single or divided into an anterior and a posterior plexus. Irrespective of whether the primary capillary plexus is single or divided, distinct, non-interconnected anterior and posterior gro... |
61,739 | Some thoughts about the treatment of patients suffering from cancer of the esophagus or cardia. | The treatment of patients suffering from carcinoma of the esophagus or the cardia is extremely difficult, and the results to date have not been encouraging. The authors are of the opinion that only relatively young patients in good general condition, with a tumor smaller than 5 cm, without metastases and without peri-e... |
61,740 | [Sinus node function in man. Statistical analysis]. | The sinus function of 60 patients was studied by atrial stimulation at a fixed rate, and also at a rate linked with the preceding sinus cycle. These patients were divided into 3 groups according to the surface-recorded ECG; 10 had clear evidence of sinus dysfunction, 23 had an isolated sinus bradycardia, and 27 were co... |
61,741 | [About the heterogeneity of the murine oncornavirus group-specific antigen gs-1 (author's transl)]. | In isoelectric focusing of twofold gradienpturified and Tween 80-ether disrupted RLV the groupspecific antigen (gs-1) was found in 3 pH-zones (4,45-5,5; 5,65-6,0; 6,45-6,6). For the gs-1 from plasma und spleen cells of leukemic mice was shown heterogeneity by several methods: 1. Gs-1 from plasma showed in isoelectric f... |
61,742 | Thyroid-bound Y-chromatin-like fluorescence in the nuclei of thyroid adenomas. | Brilliantly fluorescent supernumerary chromocenters indistinguishable from the Y-chromatin have been often found electively in the thyroid nuclei. The authors compared the occurrence of this Y-chromatin-like fluorescence in 31 thyroid adenomas obtained from 30 autopsy cases (10 males, 20 females) with non-adenomatous t... |
61,743 | [Pulse cytophotometric and cytologic repeated examinations of cervical secretions as compared with histologic findings (author's transl)]. | 1625 cervical smears from 397 women were investigated in special cytological consultations. On the same material 693 impulse cytophotometric (ICP) measurements were made, stained with ethidium bromide after pepsination. In 207 patients the diagnosis was certain by histology. The mean height of the 4c-peak (in 0/00 of t... |
61,744 | Correlative light and electron microscopy of the frog adrenal gland cells using adjacent epon-embedded sections. | Correlative light and electron microscopy on the same cells of the adrenal gland of the frog, Rana nigromaculata, fixed in glutaraldehyde followed by osmium tetroxide, was done using the adjacent Epon embedded sections. Electron microscope observation revealed three different types of granule-filled secretory cells; th... |
61,747 | Comparative serological studies with mammalian adenoviruses. | Nine serotypes of bovine adenovirus, five serotypes of ovine adenovirus, and four serotypes of porcine adenovirus were compared in reciprocal cross-neutralisation tests, to determine if viruses isolated from different species were indeed distinct serotypes. In addition, the above serotypes were tested for possible anti... |
61,748 | Development of a new human polyoma virus strain (MG). | A polyoma virus isolated from the urine of a renal transplant patient has been grown on primary human foetal fibroblasts and its pattern of replication studied by thin section electron microscopy. Virus replication is characterized by the appearance of spherical, crystalline arrays in the nucleoplasm which differ from ... |
61,750 | Hemorrhages with optic nerve drusen. A differentiation from early papilledema. | The distinction between early papilledema and drusen of the optic disk may be made more difficult by the presence of hemorrhages. We report five patients with drusen of the optic disk and associated hemorrhages. The distinguishing characteristics of both conditions are described. |
61,751 | Alpha fetoprotein in liver disease in Papua New Guinea. | A radioimmunoassay method was used for the detection of alpha fetoprotein (AFP) in the sera of 112 Papua New Guinean patients who had undergone liver biopsy. Sera from 69 normal subjects and 20 hospital patients were also tested. Alpha fetoprotein was found to be elevated above normal levels in many of these subjects, ... |
61,752 | Immediate hypersensitivity: a clinical review. | Diseases in which immediate hypersensitivity (IH) reactions occur, (asthma, allergic rhinitis and eczema) are very common in Australia although their overall prevalence is unknown. Until recently the clinical investigation of IH has been undertaken almost exclusively by allergists using scratch tests. The discovery of ... |
61,753 | Hepatitis B antigen subtypes in asymptomatic carriers in the Solomon Islands. | Three hundred and fifty-three students attending King George VI School in Honiara, British Solomon Islands Protectorate, were tested by immunodiffusion for hepatitis B surface antigen (HBS Ag). The prevalence of HB Ag was 13% and the antigen was found more frequently in males. Twenty-seven samples which contained high ... |
61,754 | Evaluation of insecticide smears for the control of screw-worm fly, Chrysomya bezziana, in Papua New Guinea. | Three new insecticide smear preparations for the control of Chrysomya bezziana larvae infesting wounds of cattle have been tested under field and laboratory conditions and compared with an established preparation EQ 335 which is based on 3% lindane. Two preparations based on 3% coumaphos proved comparable to EQ 335 in ... |
61,757 | Multifocal ventricular parasystolic tachycardia. | Two cases of spontaneous multifocal ventricular parasystolic rhythm are described. One case showed double and the other fivefold parasystole. All seven foci had an enhanced rate of discharge, ranging from 57 to 102/min and at least three of them showed exit block. Though beats from three foci displayed very short coupl... |
61,756 | [Mesenteric panniculitis]. | A 4-year-old girl was studied at the Pediatrics Unit at the Hospital General de México, S.S.A., with a diagnosis of abdominal tumor, probably malignant. After several laboratory tests (blood count, blood chemistry, catecholamines and the following X-ray studies: chest, skull, long bones, Cava's phlebography and excreto... |
61,758 | Anatomical variants in aortic atresia. Potential candidates for ventriculoaortic reconstitution. | Aortic valve atresia is usually associated with severe hypoplasia of the left ventricle and mitral apparatus. Palliative procedures, including atrial septectomy, pulmonary artery-aorta anastomosis, and pulmonary artery banding, have been performed in some patients. However, because of the distinct underdevelopment of t... |
61,761 | Ophthalmoscopic signs of obstructed axoplasmic transport after ocular vascular occlusions. | When axoplasmic transport in ganglion-cell axons is interrupted by ischaemia organelles accumulate in distended axon terminals at the edges of the infarct. This report illustrates the localized opaque swelling of nerve fibres shich develops at or near the optic disc after occlusion of the central retinal or posterior c... |
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