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At 0510 on 13 June, a large sheet of flame and dense smoke were seen rising from the "Escanaba", though no explosion was heard by the other ships in the convoy. She sank at 0513, going down so quickly that she did not have time to send any distress signals. "Storis" and "Raritan" were ordered to investigate and rescue survivors while the rest of the convoy began zigzagging and steering evasive courses to avoid enemy submarines. Although "Storis" and "Raritan" were able to arrive on the scene within ten minutes, only two survivors and one body could be found. At 0715 the two vessels returned to the main body of the convoy, having rescued Boatswain's Mate 2nd Class Melvin A. Baldwin and Seaman 1st Class Raymond F. O'Malley Jr., and having found the body of LT Prause. The entire crew of 13 officers and 92 men was lost to the explosion or to rapid hypothermia in the water with the exception of Baldwin and O'Malley, whose survival was attributed to their soaked clothing having frozen their unconscious bodies to floating debris, which prevented them from following their shipmates to the bottom.
https://en.wikipedia.org/wiki?curid=5856358
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"M. fortuitum" infection can be a nosocomial (hospital acquired) disease. Surgical sites may become infected after the wound is exposed directly or indirectly to contaminated tap water. Other possible sources of "M. fortuitum" infection include implanted devices such as catheters, injection site abscesses, and contaminated endoscopes. Recent publication on Rapidly Growing Mycobacteria (RGM) is available provides the following aspects of RGM: (i) its sources, predisposing factors, clinical manifestations, and concomitant fungal infections; (ii) the risks of misdiagnoses in the management of RGM infections in dermatological settings; (iii) the diagnoses and outcomes of treatment responses in common and uncommon infections in immunocompromised and immunocompetent patients; (iv) conventional versus current molecular methods for the detection of RGM; (v) the basic principles of a promising MALDI-TOF MS, sampling protocol for cutaneous or subcutaneous lesions and its potential for the precise differentiation of "M. fortuitum", "M. chelonae", and "M. abscessus"; and (vi) improvements in RGM infection management as described in the recent 2011 Clinical and
https://en.wikipedia.org/wiki?curid=9979405
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The LCHC has participated in key cross-cultural studies, such as research projects with the Kpelle people and the Vai people (both of Liberia), and rural residents in Yucatan, Mexico. These studies were instrumental in formulating a critique of contemporaneous methods of cross-cultural and developmental psychology. LCHC researchers argued that studies of human cognitive activity must be grounded in the actual materials and processes of people's daily lives (ecological validity). Using this approach, they demonstrated that years of schooling strongly influence performance on many common cognitive tasks, but that such influences do not support the conclusion of a general cognitive impact of schooling on cognitive development. This work called into question the use of cognitive tasks to measure school achievement by showing that schooled children scored better on psychological tests while performing far below expectations on their schoolwork. This finding refocused research attention to the link between activities that children engaged in outside of formal schooling and their performance in the classroom. The interplay between informal and formal educational activities continues to concern LCHC researchers today.
https://en.wikipedia.org/wiki?curid=29122882
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New evidence for a vast northern ocean was published in May 2016. A large team of scientists described how some of the surface in Ismenius Lacus quadrangle was altered by two tsunamis. The tsunamis were caused by asteroids striking the ocean. Both were thought to have been strong enough to create 30 km diameter craters. The first tsunami picked up and carried boulders the size of cars or small houses. The backwash from the wave formed channels by rearranging the boulders. The second came in when the ocean was 300 m lower. The second carried a great deal of ice which was dropped in valleys. Calculations show that the average height of the waves would have been 50 m, but the heights would vary from 10 m to 120 m. Numerical simulations show that in this particular part of the ocean two impact craters of the size of 30 km in diameter would form every 30 million years. The implication here is that a great northern ocean may have existed for millions of years. One argument against an ocean has been the lack of shoreline features. These features may have been washed away by these tsunami events. The parts of Mars studied in this research are Chryse Planitia and northwestern Arabia Terra. These tsunamis affected some surfaces in the Ismenius Lacus quadrangle and in the Mare Acidalium quadrangle. The impact that created the crater Lomonosov has been identified as a likely source of tsunami waves.
https://en.wikipedia.org/wiki?curid=20573621
1,117,319
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In 1997, the news division of WTVT (Channel 13), a Fox-owned station in Tampa, Florida, planned to air an investigative report by Steve Wilson and Jane Akre on the health risks associated with Monsanto's bovine growth hormone product, Posilac. Just before the story was to air, Fox received a letter from Monsanto saying the reporters were biased and that the story would damage the company. Akre stated that Wilson and she went through 83 rewrites over eight months. Negotiations broke down and both reporters were eventually fired. Wilson and Akre alleged the firing was for retaliation, while WTVT contended they were fired for insubordination. The reporters then sued Fox/WTVT in Florida state court under the state's whistleblower statute. In 2000, a Florida jury found that while no evidence showed Fox/WTVT had bowed to any pressure from Monsanto to alter the story, Akre, but not Wilson, was a whistleblower and was unjustly fired. She was awarded a $425,000 settlement. At the time of the decision, "the station claimed it did not bend to Monsanto's letter and wanted to air a hard-hitting story with a number of statements critical of Monsanto." Fox appealed the decision stating that under Florida law, a whistleblower can only act if "a law, rule, or regulation" has been broken and argued that the FCC's policy against distortions or misrepresentations presented as news did not fit that definition. On 14 February 2003, the appeals court overturned the verdict, finding that Akre was not a whistleblower because of the Florida "legislature's requirement that agency statements that fit the definition of a "rule" (must) be formally adopted (rules). Recognizing an uncodified agency policy developed through the adjudicative process as the equivalent of a formally adopted rule is not consistent with this policy, and it would expand the scope of conduct that could subject an employer to liability beyond what Florida's Legislature could have contemplated when it enacted the whistle-blower's statute."
https://en.wikipedia.org/wiki?curid=543002
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Membrane contact sites (MCS) are close appositions between two organelles. Ultrastructural studies typically reveal an intermembrane distance in the order of the size of a single protein, as small as 10 nm or wider, with no clear upper limit. These zones of apposition are highly conserved in evolution. These sites are thought to be important to facilitate signalling, and they promote the passage of small molecules, including ions, lipids and (discovered later) reactive oxygen species. MCS are important in the function of the endoplasmic reticulum (ER), since this is the major site of lipid synthesis within cells. The ER makes close contact with many organelles, including mitochondria, Golgi, endosomes, lysosomes, peroxisomes, chloroplasts and the plasma membrane. Both mitochondria and sorting endosomes undergo major rearrangements leading to fission where they contact the ER. Sites of close apposition can also form between most of these organelles most pairwise combinations. First mentions of these contact sites can be found in papers published in the late 1950s mainly visualized using electron microscopy (EM) techniques. Copeland and Dalton described them as “highly specialized tubular form of endoplasmic reticulum in association with the mitochondria and apparently in turn, with the vascular border of the cell”.
https://en.wikipedia.org/wiki?curid=21683238
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Eaton was born and raised in Philadelphia. Like many in his family, he attended the University of Pennsylvania as an undergraduate, majoring in chemistry and graduating in 1959. He then spent one year in Germany as the first Willy Brandt - University of Pennsylvania exchange student at the Free University Berlin. He entered Penn medical school in the Fall of 1960, but discovered that he was more interested in research, particularly after spending the summer of 1962 carrying out research on protein biosynthesis under the supervision of Sydney Brenner at the Laboratory of Molecular Biology, Cambridge, England. He decided to pursue a Ph.D. and became one of Penn's first M.D.-Ph.D. students, working with Robin Hochstrasser on molecular spectroscopy of single crystals of heme proteins. He received his M.D. in 1964 and his Ph.D. in 1967. After finishing his Ph.D. research, he was drafted into the military and chose to fulfill his military obligation as a medical officer in the United States Public Health Service, where he could conduct research at the National Institutes of Health.
https://en.wikipedia.org/wiki?curid=58151579
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Metal aromaticity or metalloaromaticity is the concept of aromaticity, found in many organic compounds, extended to metals and metal-containing compounds. The first experimental evidence for the existence of aromaticity in metals was found in aluminium cluster compounds of the type where M stands for lithium, sodium or copper. These anions can be generated in a helium gas by laser vaporization of an aluminium / lithium carbonate composite or a copper or sodium / aluminium alloy, separated and selected by mass spectrometry and analyzed by photoelectron spectroscopy. The evidence for aromaticity in these compounds is based on several considerations. Computational chemistry shows that these aluminium clusters consist of a tetranuclear plane and a counterion at the apex of a square pyramid. The unit is perfectly planar and is not perturbed the presence of the counterion or even the presence of two counterions in the neutral compound . In addition its HOMO is calculated to be a doubly occupied delocalized pi system making it obey Hückel's rule. Finally a match exists between the calculated values and the experimental photoelectron values for the energy required to remove the first 4 valence electrons. The first fully metal aromatic compound was a cyclogallane with a Ga core discovered by Gregory Robinson in 1995.
https://en.wikipedia.org/wiki?curid=3220879
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Very important with often a traditional meaning as well are fermentation products of mare milk, like for example the slightly-alcoholic yogurt kumis. Consumption of these peaks during cultural festivities such as the Mongolian lunar new year (in spring). The time of this celebration is called the "white month", which indicates that milk products (called "white food" together with starchy vegetables, in comparison to meat products, called "black food") are a central part of this tradition. The purpose of these festivities is to "close" the past year – clean the house or the yurt, honor the animals for having provided their food, and prepare everything for the coming summer season – to be ready to "open" the new year. Consuming white food in this festive context is a way to connect to the past and to a national identity, which is the great Mongolian empire personified by Genghis Khan. During the time of this empire, the fermented mare milk was the drink to honor and thank warriors and leading persons, it was not meant for everybody. Although it eventually became a drink for normal people, it has kept its honorable meaning. Like many other traditions, this one feels the influence of globalization. Other products, like industrial yogurt, coming mainly from China and western countries, have tended to replace it more and more, mainly in urban areas. However, in rural and poorer regions it is still of great importance.
https://en.wikipedia.org/wiki?curid=200201
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The heart of the Fabry–Pérot interferometer is a pair of partially silvered glass optical flats spaced several millimeters to centimeters apart with the silvered surfaces facing each other. (Alternatively, a Fabry–Pérot "etalon" uses a transparent plate with two parallel reflecting surfaces.) As with the Fizeau interferometer, the flats are slightly beveled. In a typical system, illumination is provided by a diffuse source set at the focal plane of a collimating lens. A focusing lens produces what would be an inverted image of the source if the paired flats were not present, i.e., in the absence of the paired flats, all light emitted from point A passing through the optical system would be focused at point A'. In Fig. 6, only one ray emitted from point A on the source is traced. As the ray passes through the paired flats, it is multiply reflected to produce multiple transmitted rays which are collected by the focusing lens and brought to point A' on the screen. The complete interference pattern takes the appearance of a set of concentric rings. The sharpness of the rings depends on the reflectivity of the flats. If the reflectivity is high, resulting in a high Q factor (i.e., high finesse), monochromatic light produces a set of narrow bright rings against a dark background. In Fig. 6, the low-finesse image corresponds to a reflectivity of 0.04 (i.e., unsilvered surfaces) "versus" a reflectivity of 0.95 for the high-finesse image.
https://en.wikipedia.org/wiki?curid=166689
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Robin Popplestone was born in Bristol in 1938, but after WWII his family moved to Belfast. He received an honours degree in mathematics from Queen's University Belfast in 1960. He started a PhD at Manchester University before moving to Leeds University. His project was to develop a program for automated theorem proving, but he got caught up in using the university computer to design a boat. He built the boat and set sail for the University of Edinburgh, where he had been offered a research position. A storm hit while crossing the North Sea, and the boat sank. A widely believed story about Popplestone was that he never completed his PhD in mathematics because he lost his thesis manuscript in the boat, although Popplestone refused to corroborate this. The early part of his professional career was spent at the University of Edinburgh (1965-1985) and the later part at the University of Massachusetts Amherst (1985-2001). In 1990, he was elected a Founding Fellow of the Association for the Advancement of Artificial Intelligence. Due to illness, he retired in 2001 to the Glasgow area. He died in 2004 after a 10-year illness with prostate cancer.
https://en.wikipedia.org/wiki?curid=2371534
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In 1948, Michigan's Institute for Social Research (ISR) was established by Rensis Likert. Harlan H. Hatcher, an administrator at Ohio State University and professor of English, was appointed university president in 1951. Hatcher fostered early construction in the school's nascent North Campus, and created an Honors College for 5% of entering freshmen. As the Cold War and the Space Race took shape, UM became a principal recipient of government research grants, and its researchers were on the vanguard of exploring peacetime uses for atomic power. During Hatcher's administration, the ISR, with its ambitious ongoing effort focused on research and applications of social science, received its own building. In a 1966 report by the American Council on Education, the university was rated first or second in the nation in graduate teaching of all 28 disciplines surveyed. In 1971, the central library on campus was named the Harlan Hatcher Graduate Library.
https://en.wikipedia.org/wiki?curid=2147828
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A conceptual model of early behavior and migration of green sturgeon early life intervals based on the Kynard et al. 2005 study follows: Females deposit eggs at sites with large rocks and moderate or eddy water flow that keeps the large, dense, poorly adhesive eggs from drifting, so eggs sink deep within the rocks. CH2M Hill (2002) assumed that hatchling green sturgeon embryos drift downstream like hatchling white sturgeon embryos. This was incorrect. Hatchling green sturgeon embryos seek nearby cover, and remain under rocks, unlike white sturgeon which drift downstream as embryos (i.e. newly hatched green sturgeon do not exhibit pelagic behavior like newly hatched white sturgeon) (Deng et al. 2002). After about 9 days fish develop into larvae and initiate exogenous foraging up- and downstream on the bottom (they do not swim up into the water column, unlike white sturgeon). After a day or so, larvae initiate a downstream dispersion migration that lasts about 12 days (peak, 5 days). At the age of ten days, when exogenous foraging begins, green sturgeons are in length (mean ) (Deng et al. 2002). At the age of 15 to 21 days, green sturgeon are or greater in length (Deng et al. 2002). At the age of 45 days, metamorphosis is complete and green sturgeon are 70 to in length (Deng et al. 2002). All migration and foraging during the migration period is nocturnal, unlike white sturgeon. During the first 10 months of life, green sturgeon are the most nocturnal of any North American sturgeon yet studied, and this was the case for all life intervals during any activity (migration, foraging, or wintering). Post-migrant larvae are benthic, foraging up- and downstream diurnally with a nocturnal activity peak. Foraging larvae select open habitat, not structure habitat, but continue to use cover in the day. When larvae develop into juveniles, there is no change in response to bright habitat, and no preference or avoidance of bright habitat. In the fall, juveniles migrate downstream mostly at night to wintering sites, ceasing migration at . During winter, juveniles select low light habitat, likely deep pools with some rock structure. Wintering juveniles forage actively at night between dusk and dawn and are inactive during the day, seeking the darkest available habitat.
https://en.wikipedia.org/wiki?curid=9868153
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Set more than 21,000 years in the future, the background story of "Eve Online" explains that humanity, having used up most of Earth's resources through centuries of explosive population growth, began colonizing the rest of the Milky Way. As on Earth, this expansion also led to competition and fighting over available resources, but everything changed with the discovery of a natural wormhole leading to an unexplored galaxy subsequently dubbed "New Eden." Dozens of colonies were founded, and a structure, a gate of sorts (which bears the inscription "EVE" on the New Eden side), was built to stabilize the wormhole that linked the colonies of New Eden with the rest of human civilization. However, when the wormhole unexpectedly collapsed, it destroyed the gate as well as the connection between the colonies of New Eden and the Milky Way. Cut off from the rest of humanity and supplies from Earth, the colonies of New Eden were left starving and disconnected from one another; many died out entirely. Over the millennia the descendants of the surviving colonists managed to rebuild their own societies, but by this time the memories and knowledge of humanity's origins, of Earth and the Milky Way galaxy, as well as the history of the settling of New Eden, were lost; what little information that survived transmission over the generations was misunderstood, lost in translation, or consigned to mythology. Five major distinct societies rose to prominence from the surviving colonies, all growing into interstellar spaceflight-capable civilizations. The states based around these societies make up the four major empires in "Eve Online": the Amarr Empire, the Caldari State, the Gallente Federation, the Minmatar Republic, and the Jove Empire.
https://en.wikipedia.org/wiki?curid=403307
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Tropical medicine requires an interdisciplinary approach, as the infections and diseases tropical medicine faces are both broad and unique. Tropical medicine requires research and assistance from the fields of epidemiology, microbiology, virology, parasitology, and logistics. Physicians of tropical medicine must have effective communication skills, as many of the patients they interact with do not speak English comfortably. They must be proficient in their knowledge of clinical and diagnostic skills, as they are often without high-tech diagnostic tools when in the field. For example, in an attempt to manage the Chagas disease being brought into the almost Chagas-free Brazilian city São Paulo by Bolivian immigrants, an interdisciplinary team was set up. The Bolivian immigrant population in São Paulo had a prevalence of Chagas disease of 4.4%, while Chagas disease transmission in São Paulo has been under control since the 1970s. This influx of Chagas disease led to an interdisciplinary team being brought together, This team tested the feasibility of managing Chagas disease and transmission at the primary healthcare level. The interdisciplinary team consisted of community health agents and clerical healthcare workers to recruit Chagas infected persons for the study, physicians, nurses, lab workers, and community agents. A pediatrician and cardiologist were also on call. Each were trained in pathology, parasitology, ecoepidemiology, and how to prevent, diagnose, and control Chagas disease. Training from experts in these respective fields was required. They examined reasons for lack of adherence to treatment, and used this knowledge to improve the effectiveness of their interventions. This interdisciplinary approach has been used to train many teams across Brazil in the management of Chagas disease.
https://en.wikipedia.org/wiki?curid=1072877
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There are also indirect ways of applying "weighted" adjustments. For example, the existing cases may be duplicated to impute missing observations (e.g.: from non-response), with variance estimated using methods such as multiple imputation. A complementary dealing of data is to remove (give weight of 0) to some cases. For example, when wanting to reduce the influence of over-sampled groups that are less essential for some analysis. Both cases are similar in nature to inverse probability weighting but the application in practice gives more/less rows of data (making the input potentially simpler to use in some software implementation), instead of applying an extra column of weights. Nevertheless, the consequences of such implementations are similar to just using weights. So while in the case of removing observations the data can easily be handled by common software implementations, the case of adding rows requires special adjustments for the uncertainty estimations. Not doing so may lead to erroneous conclusions(i.e.: there is no free lunch when using alternative representation of the underlying issues).
https://en.wikipedia.org/wiki?curid=26286630
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She wanted to continue her studies and since women were not yet admitted to graduate schools in England she went to the University of Göttingen in Germany to study with Felix Klein. This was one of the major mathematical centres in the world. She had fortunately already learnt the German language. The decision to admit her had to be approved by the Berlin Ministry of Culture and was part of an experiment in admitting women to university studies. In 1895, at the age of 27, Chisholm was awarded a doctorate in mathematics. Again government approval had to be obtained to allow her to take the examination, which consisted of probing questions by several professors on sections such as geometry, differential equations, physics, astronomy, and the area of her dissertation, all in German. Along with her test she was required to take courses showing broader knowledge as well as prepare a thesis which was entitled "Algebraisch-gruppentheoretische Untersuchungen zur sphärischen Trigonometrie" ("Algebraic Groups of Spherical Trigonometry").
https://en.wikipedia.org/wiki?curid=239997
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Air masses can be modified in a variety of ways. Surface flux from underlying vegetation, such as forest, acts to moisten the overlying air mass. Heat from underlying warmer waters can significantly modify an air mass over distances as short as to . For example, southwest of extratropical cyclones, curved cyclonic flow bringing cold air across the relatively warm water bodies can lead to narrow lake-effect snow bands. Those bands bring strong localized precipitation since large water bodies such as lakes efficiently store heat that results in significant temperature differences (larger than 13 °C or 23 °F) between the water surface and the air above. Because of this temperature difference, warmth and moisture are transported upward, condensing into vertically oriented clouds (see satellite picture) which produce snow showers. The temperature decrease with height and cloud depth are directly affected by both the water temperature and the large-scale environment. The stronger the temperature decrease with height, the deeper the clouds get, and the greater the precipitation rate becomes.
https://en.wikipedia.org/wiki?curid=261690
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Service members began to complain about side effects of the vaccine, and debate ensued about whether these problems were really vaccine-related. The DOD maintained that the vaccine was safe, but surveys showed that many service members did not believe the information that was being given to them about it. Treatment of troops who refused or hesitated was up to the discretion of their commanding officers, and therefore varied widely. Some were not punished at all, others acquiesced after further counseling, while still others received serious penalties such as dishonorable discharges. Following the 9/11 attacks, an exemption requested by marine James Muhammad led to his court martial, with his lawyer advising him to plead guilty because he would not be allowed to present his religious reasons and might be subject to the death penalty. The legal situation was complicated by the fact that the vaccine was experimental. Although service members are required to obey orders, it is also illegal under US law to use an experimental drug on patients without their consent. In the reserves, the requirement led many members to quit, switch to inactive status, or move to another unit. In the Air Force Reserve, a GAO report cited a negative effect on "retention of trained and experienced guard and reserve pilots."
https://en.wikipedia.org/wiki?curid=7863675
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In addition to deploying F-35Bs on amphibious assault ships, the USMC plans to disperse the aircraft among austere forward-deployed bases with shelter and concealment to enhance survivability while remaining close to a battlespace. Known as distributed STOVL operations (DSO), F-35Bs would operate from temporary bases in allied territory within hostile missile engagement zones and displace inside the enemy's 24- to 48-hour targeting cycle; this strategy allows F-35Bs to rapidly respond to operational needs, with mobile forward arming and refueling points (M-FARPs) accommodating KC-130 and MV-22 Osprey aircraft to rearm and refuel the jets, as well as littoral areas for sea links of mobile distribution sites. For higher echelons of maintenance, F-35Bs would return from M-FARPs to rear-area friendly bases or ships. Helicopter-portable metal planking is needed to protect unprepared roads from the F-35B's exhaust; the USMC are studying lighter heat-resistant options. These operations have become part of the larger USMC Expeditionary Advanced Base Operations (EABO) concept.
https://en.wikipedia.org/wiki?curid=11812
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State colleges and universities had depended largely on grants from the legislature, ignoring fund-raising, philanthropy. They kept tuition close to zero. Many were very hard-pressed by the Great Depression—it almost shut down the University of Colorado, as the legislature slashed its budget, there was practically no endowment, and tuition was already very low. The medical school was nearly closed in 1938 – it survived when the legislature allowed it to borrow more money. In 1939. The main campus in Boulder came within a few days of having to close. The bright spot came in the building projects. The PWA spent nearly $1 million on 15 new buildings on the Boulder campus and the medical school campus in Denver. That included a fieldhouse, a natural history museum, new wings for the college of arts and sciences, a faculty club, a small library and a new hospital. The RFC loaned $550,000 in 1933 to build women's dormitories, with the loans repaid through room and board charges.
https://en.wikipedia.org/wiki?curid=44440652
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The main alternative to magnetic confinement is inertial confinement fusion (ICF), such as that proposed by Project Daedalus. A small pellet of fusion fuel (with a diameter of a couple of millimeters) would be ignited by an electron beam or a laser. To produce direct thrust, a magnetic field forms the pusher plate. In principle, the Helium-3-Deuterium reaction or an aneutronic fusion reaction could be used to maximize the energy in charged particles and to minimize radiation, but it is highly questionable whether using these reactions is technically feasible. Both the detailed design studies in the 1970s, the Orion drive and Project Daedalus, used inertial confinement. In the 1980s, Lawrence Livermore National Laboratory and NASA studied an ICF-powered "Vehicle for Interplanetary Transport Applications" (VISTA). The conical VISTA spacecraft could deliver a 100-tonne payload to Mars orbit and return to Earth in 130 days, or to Jupiter orbit and back in 403 days. 41 tonnes of deuterium/tritium (D-T) fusion fuel would be required, plus 4,124 tonnes of hydrogen expellant. The exhaust velocity would be 157 km/s.
https://en.wikipedia.org/wiki?curid=37852
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The problems with the S-II and the S-IVB were traced to the J-2 engines, present in both stages. Tests showed that the spark igniters on the propellant lines could fail in low atmospheric pressure or in vacuum. This problem would not happen in ground testing, where the cold liquid gases passing through the propellant lines would induce a protective layer of frost; further, during such testing, liquid air was sprayed over the engines' exteriors, damping out any vibrations. In the vacuum of space, there was no such protection: the bellows adjacent to the spark igniters vibrated rapidly and failed at peak flow, causing a burn-through of the propellant lines. The bellows were eliminated and the lines strengthened. In Apollo 6's wake, NASA engineers debated whether to configure the spacecraft's emergency detection system to automatically abort in the event of excessive pogo; this plan was opposed by Director of Flight Crew Operations Deke Slayton. Instead, work began on having a "pogo abort sensor" to allow the flight crew to judge whether to abort, but by August 1968, it had become clear that pogo could be dealt with without such a sensor, and work on it was abandoned.
https://en.wikipedia.org/wiki?curid=231436
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While phytogeomorphology studies the relationship between plants and terrain attributes in general (see Howard et al., (1985)), it can also apply to precision agriculture by studying crop growth temporal and spatial variability within farm fields. There is already a volume of work, although they don't use the term phytogeomorphology specifically, that considers farm field terrain attributes as affecting crop yield and growth, Moore et al. (1991) provide an early overview of the application of terrain features to precision agriculture, but one of the earliest references to this phenomenon in farming is that of Whittaker in 1967. More recent work includes a six-year study of temporal and spatial yield stability over 11 years (Kaspar et al., (2003), and references therein), and a detailed study of the same on a small patch farm in Portugal (and references therein). This variability can be exploited to produce higher yields and reduce the environmental impact of farming - consequently returning a higher profit to the farmer in terms of higher overall yields and lesser amounts of inputs. The new science of Sustainable Intensification of Agriculture which is addressing the need for higher yields from existing fields can be fulfilled by some of the practical applications of phytogeomorphology applied to precision agriculture.
https://en.wikipedia.org/wiki?curid=39984881
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Humans have directly influenced the genetic makeup of plants to increase their value as a crop through domestication. The first evidence of plant domestication comes from emmer and einkorn wheat found in pre-Pottery Neolithic A villages in Southwest Asia dated about 10,500 to 10,100 BC. The Fertile Crescent of Western Asia, Egypt, and India were sites of the earliest planned sowing and harvesting of plants that had previously been gathered in the wild. Independent development of agriculture occurred in northern and southern China, Africa's Sahel, New Guinea and several regions of the Americas. The eight Neolithic founder crops (emmer wheat, einkorn wheat, barley, peas, lentils, bitter vetch, chick peas and flax) had all appeared by about 7,000 BC. Traditional crop breeders have long introduced foreign germplasm into crops by creating novel crosses. A hybrid cereal grain was created in 1875, by crossing wheat and rye. Since then traits including dwarfing genes and rust resistance have been introduced in that manner. Plant tissue culture and deliberate mutations have enabled humans to alter the makeup of plant genomes.
https://en.wikipedia.org/wiki?curid=2291204
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Synchrotron radiation may occur in accelerators either as a nuisance, causing undesired energy loss in particle physics contexts, or as a deliberately produced radiation source for numerous laboratory applications. Electrons are accelerated to high speeds in several stages to achieve a final energy that is typically in the gigaelectronvolt range. The electrons are forced to travel in a closed path by strong magnetic fields. This is similar to a radio antenna, but with the difference that the relativistic speed changes the observed frequency due to the Doppler effect by a factor formula_8. Relativistic Lorentz contraction bumps the frequency by another factor of formula_8, thus multiplying the gigahertz frequency of the resonant cavity that accelerates the electrons into the X-ray range. Another dramatic effect of relativity is that the radiation pattern is distorted from the isotropic dipole pattern expected from non-relativistic theory into an extremely forward-pointing cone of radiation. This makes synchrotron radiation sources the most brilliant known sources of X-rays. The planar acceleration geometry makes the radiation linearly polarized when observed in the orbital plane, and circularly polarized when observed at a small angle to that plane.
https://en.wikipedia.org/wiki?curid=379507
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Individuals have a something to lose as well when it comes to contracting the disease of SARS-CoV-2. For many hourly workers, this sick time off results in lost income and many salaried workers are able to do some work from a home office. Both of these situations can have positive and negative outcomes; whether it's getting additional assistance from the enhanced unemployment benefits for the greater part of 2021, or working from home with poor internet connectivity or no dedicated workspace. These headaches for many potentially contributed to the difference in reported incidence versus estimated-actual incidence rates of Covid-19 within a population. A 2020 cross-sectional study published in the JAMA Internal Medicine Journal performed blood testing on a convenience sample in 10 geographic sites across the United States and found that based on seroprevalence there were 10 times more cases than was being reported.
https://en.wikipedia.org/wiki?curid=17601160
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The Beecroft Building is a new construction at the Department of Physics, which was designed by architects Hawkins/Brown in 2018. It is located directly in front of the Clarendon laboratory along Parks Road. This section of the physics department was dedicated towards Adrian Beecroft, who contributed to the funding of the 50-million-pound project. The sub-types of physics that this facility focuses on includes theoretical and experimental physics. This building was constructed to unite researchers who study theoretical and experimental physics and allow them to collaborate in controlled conditions. The architecture of this building consists of a combination of bronze, glass and expanded copper mesh insert panels accompanied by a grid of weathering bronze fins. The physical structure of the building was built 16 metres underground to accommodate the “Carfax height” policy, which does not allow buildings in central Oxford to be higher than 18 metres. The 16-metre basement was also designed for specific laboratories that require vibrational isolation.
https://en.wikipedia.org/wiki?curid=47616060
1,773,568
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As chemical analytes have their own specific refractive indices, they can fill porous photonic structures, altering their effective index and consequently their color in a finger-print like manner. On the other hand, they can alter the volume of polymer-based structures, resulting in a change in the periodicity leading to a similar end effect. In ion-containing hydrogels, their selective swelling results in their specificity. Applications in gaseous and aqueous environment have been studied to detect concentrations of chemical species, solvents, vapors, ions, pH and humidity. The specificity and sensitivity can be controlled by the appropriate choice of materials and their interaction with the analytes, that can achieve even label-free sensors. The concentration of chemical species in vapor or liquid phases as well as in more complex mixtures can be determined with high confidence.
https://en.wikipedia.org/wiki?curid=67527532
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Besides the clinical setting, SEPs have shown to be useful in distinct experimental paradigms. Schubert et al. (2006) used SEPs to investigate the differential processing of consciously perceived versus unperceived somatosensory stimuli. The authors used an 'extinction' paradigm to examine the connection between activation of S1 and somatosensory awareness, and observed that early SEPs (P60, N80), generated in the contralateral S1, were independent of stimulus perception. In contrast, amplitude enhancements were observed for the P100 and N140 for consciously perceived stimuli. The authors concluded that early activation of S1 is not sufficient to warrant conscious stimulus perception. Conscious stimulus processing differs significantly from unconscious processing starting around 100 ms after stimulus presentation when the signal is processed in parietal and frontal cortices, brain regions crucial for stimulus access into conscious perception. In another study, Iwadate et al. (2005) looked at the relationship between physical exercise and somatosensory processing using SEPs. The study compared SEPs in athletes (soccer players) and non-athletes, using two oddball tasks following separate somatosensory stimulation at the median nerve and at the tibial nerve. In the athlete group the N140 amplitudes were larger during upper- and lowerlimb tasks when compared to non-athletes. The authors concluded that plastic changes in somatosensory processing might be induced by performing physical exercises that require attention and skilled movements.
https://en.wikipedia.org/wiki?curid=27326458
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Despite the growing criticisms of trait leadership, the purported basis for the rejection of trait-leadership models began to encounter strong challenges (Kenny & Zaccaro, 1983; Lord, DeVader, & Alliger, 1986) in the 1980s. Zaccaro (2007) pointed out that even Stogdill's (1948) review, although cited as evidence against leader traits, contained conclusions supporting that individual differences could still be predictors of leader effectiveness. With an increasing number of empirical studies directly supporting trait leadership (Judge et al., 2002; Judge, Colbert, & Ilies, 2004), traits have reemerged in the lexicon of the scientific research into leadership. In recent years, the research about leader traits has made some progress in identifying a list of personality traits that are highly predictive of leader effectiveness. Additionally, to account for the arguments for situational leadership, researchers have used the round-robin design methodology to test whether certain individuals emerge as leaders across multiple situations (Kenny & Zaccaro, 1983). Scholars have also proposed new ways of studying the relationship of certain traits to leader effectiveness. For instance, many suggest the integration of trait and behavioral theories to understand how traits relate to leader effectiveness (Derue et al., 2011). Furthermore, scholars have expanded their focus and have proposed looking at more malleable traits (ones susceptible to development) in addition to the traditional dispositional traits as predictors of leader effectiveness (Hoffman, Woehr, Maldagen-Youngjohn, & Lyons, 2011). Context is only now beginning to be examined as a contributor to leaders' success and failure. Productive narcissism|Productive narcissistit CEOs like Steven Jobs of Apple and Jack Welch of GE have demonstrated a gift for creating innovation, whereas leaders with idealized traits prove more successful in more stable environments requiring less innovation and creativity (Maccoby, 2007).
https://en.wikipedia.org/wiki?curid=33488970
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Wright and her father introduced nitrogen mustard agents, similar to the mustard gas compounds used in World War I, that were successful in treating the cancerous cells of leukemia patients. Wright later pioneered combinatorial work in chemotherapeutics, focusing not simply on administering multiple drugs, but sequential and dosage variations to increase the effectiveness of chemotherapy and minimize side effects. She was successful in identifying treatments for both breast and skin cancer, developing a chemotherapy protocol that increased skin cancer patient lifespans up to ten years. She also developed a non-surgical method, using a catheter system, to deliver potent drugs to tumors located deep within the body such as the liver and spleen. She published more than 100 papers on cancer chemotherapeutics during her career and served on the editorial board of the Journal of the National Medical Association.
https://en.wikipedia.org/wiki?curid=15862301
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The chief practical difficulties with antimatter rockets are the problems of creating antimatter and storing it. Creating antimatter requires input of vast amounts of energy, at least equivalent to the rest energy of the created particle/antiparticle pairs, and typically (for antiproton production) tens of thousands to millions of times more. Most storage schemes proposed for interstellar craft require the production of frozen pellets of antihydrogen. This requires cooling of antiprotons, binding to positrons, and capture of the resulting antihydrogen atoms - tasks which have, , been performed only for small numbers of individual atoms. Storage of antimatter is typically done by trapping electrically charged frozen antihydrogen pellets in Penning or Paul traps. There is no theoretical barrier to these tasks being performed on the scale required to fuel an antimatter rocket. However, they are expected to be extremely (and perhaps prohibitively) expensive due to current production abilities being only able to produce small numbers of atoms, a scale approximately 10 times smaller than needed for a 10-gram trip to Mars.
https://en.wikipedia.org/wiki?curid=37854
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Little known in the earlier part of his life, mostly as a student and follower of Schoenberg, but also as a peripatetic and often unhappy theater music director with a mixed reputation as an exacting conductor, Webern came to some prominence and increasingly high regard as a vocal coach, choirmaster, conductor, and teacher during Red Vienna. With Schoenberg away at the Prussian Academy of Arts (and with the benefit of a publication agreement secured through Universal Edition), Webern began writing music of increasing confidence, independence, and scale during the latter half of the 1920s—his mature chamber and orchestral works, music that, perhaps more than his earlier expressionist works, would later decisively influence a generation of composers. Amid Austrofascism, Nazism, and World War II, Webern remained nevertheless committed to taking the "path to the new music", as he styled it in a series of private lectures delivered in 1932–1933 (but unpublished until 1960). He continued writing some of his most mature and later celebrated music while increasingly ostracized from official musical life as a "cultural Bolshevist", taking occasional copyist jobs from his publisher as he lost students and his conducting career.
https://en.wikipedia.org/wiki?curid=65676
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The search for the meteorites is done visually. A team of four to ten explorers, typically meteorite scientists, lives for 5–7 weeks on the ice field. Using snowmobiles spaced 30 m apart they scan the blue ice for meteorites. Once a specimen has been located its position is found using GPS and it is given an identification number. It is then placed in a sterile Teflon bag. The teams make sure that the specimen remains frozen throughout its journey back to the Antarctic Meteorite Curation Facility at the Johnson Space Center in Houston, Texas. Since 1976, ANSMET has returned over 20,000 meteorites. Meteorites of greater interest and undergoing detailed study are kept at JSC for distribution to the scientific community, though, ultimately, all samples collected by ANSMET are transferred to the Smithsonian Institution for permanent storage and curation. These meteorites are housed at the Smithsonian Museum Support Center clean room facility at Suitland, Maryland, which is modeled after the Lunar Processing Laboratory at NASA’s Lyndon B. Johnson Space Center in Houston, Texas. Of the almost 16,000 Antarctic meteorites collected since 1976, over 14,000 have been permanently transferred to the Smithsonian. Curators at the Department of Mineral Sciences at the National Museum of Natural History classify each representative chip of meteorite sent by NASA. Results and descriptions are published in the Antarctic Meteorite Newsletter, issued twice a year.
https://en.wikipedia.org/wiki?curid=1851775
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The agency's current Vision for Space Exploration will waste decades and hundreds of billions of dollars trying to reach the Moon by 2020—a glorified rehash of what we did 40 years ago. Instead of a steppingstone to Mars, NASA's current lunar plan is a detour. It will derail our Mars effort, siphoning off money and engineering talent for the next two decades. If we aspire to a long-term human presence on Mars—and I believe that should be our overarching goal for the foreseeable future—we must drastically change our focus. Our purely exploratory efforts should aim higher than a place we've already set foot on six times. In recent years my philosophy on colonizing Mars has evolved. I now believe that human visitors to the Red Planet should commit to staying there permanently. One-way tickets to Mars will make the missions technically easier and less expensive and get us there sooner. More importantly, they will ensure that our Martian outpost steadily grows as more homesteaders arrive. Instead of explorers, one-way Mars travelers will be 21st-century pilgrims, pioneering a new way of life. It will take a special kind of person. Instead of the traditional pilot/scientist/engineer, Martian homesteaders will be selected more for their personalities—flexible, inventive and determined in the face of unpredictability. In short, survivors.
https://en.wikipedia.org/wiki?curid=25236027
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Soren is known in archaeology primarily for three discoveries. His archaeological excavations at Kourion, Cyprus were designed to identify the epicenter of the famous Mediterranean earthquake of July 21, 365 A.D. He located the epicenter of this mega-disaster offshore approximately 25 miles southwest of the town of Kourion. Brian Fagan described this discovery as one of the 50 most significant in world archaeology. His second discovery was the identification of "Plasmodium falciparum" malaria as a significant contributor to the downfall of the Roman Empire. This was done through analysis of DNA of infant bones from a cemetery he excavated at Lugnano in Teverina, Umbria between 1987 and 1991 – the first such use of DNA evidence on an archaeological site. The third discovery was the site of the famous Roman "fontes Clusini" or Springs of Chiusi, a healing sanctuary featuring a cold water spring said by the poet Horace in his "Epistles" to have cured the gravely ill emperor Augustus from his stomach pains in 23 B.C. Soren discovered the largest cold water ancient spring and sanctuary in Italy, near Chiusi in the Tuscan town of Chianciano Terme. The ancient spring he found was still flowing and the water contained large amounts of calcium sulfate which functions as a strong laxative.
https://en.wikipedia.org/wiki?curid=32942836
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The 2020–21 UC Irvine Anteaters men's basketball team represented the University of California, Irvine in the 2020–21 NCAA Division I men's basketball season. They played their home games at the Bren Events Center in Irvine, California as a member of the Big West Conference. The Anteaters were led by 11th-year head coach Russell Turner. The team finished the season with an 18–9 (10–4) record finishing 2nd place in the standings and advanced to the 2021 Big West Conference men's basketball tournament where they were defeated by UC Santa Barbara 63–79. The Anteaters continued their success finishing 1st or 2nd for 7 straight seasons in the Big West Conference and 4 straight Big West tournament Championship games (the 2020 Big West Conference men's basketball tournament was canceled due to the COVID-19 pandemic). The school set a new scoring record and the largest margin of victory (80) on November 28, 2020 over NAIA opponent Bethesda University by the score of 135–55. Also new school records broken in that game were assists (31) and FGs made (56). New Bren Events Center records broken were the most points scored in a first half (70) and game FG % (0.691).
https://en.wikipedia.org/wiki?curid=65989843
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The term “industrial archaeology” was popularised in Great Britain in 1955 by Michael Rix of Birmingham University, who wrote an article in "The Amateur Historian", about the need for greater study and preservation of 18th and 19th century industrial sites and relics of the British industrial revolution. In 1959, Council for British Archaeology (CBA) established an industrial archaeology research committee. The CBA soon developed a standardized record card for industrial monuments, which it distributed to volunteer groups around the UK. In 1965, the National Record of Industrial Monuments (NRIM) was created as a central archive for the record cards that had been collected by Angus Buchanan at the University of Bath. By the late 1960s, a number of local industrial archaeology groups had been formed in the UK, including the Gloucestershire Society for Industrial Archaeology in 1963, the Bristol Industrial Archaeological Society in 1967, and the Greater London Industrial Archaeology Society in 1968, among others. The primary mission of these local IA groups during this period was recording the remaining relics of industrial history, especially those deemed to be most at risk from urban redevelopment schemes. Depending on the condition of the site or artifact, recording typically consists of compiling a brief summary of the site's history through available records, including old maps or photographs, followed by detailed onsite measurements, drawings and photographs of the existing conditions of the site. Generally, a report is prepared and copies are filed in a public archive for the benefit of future generations. Most recording trips are intended to obtain a general overview of existing conditions, and are not meant to be an exhaustive study.
https://en.wikipedia.org/wiki?curid=153392
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When people are ingesting high levels of biotin in dietary supplements, a consequence can be clinically significant interference with diagnostic blood tests that use biotin-streptavidin technology. This methodology is commonly used to measure levels of hormones such as thyroid hormones, and other analytes such as 25-hydroxyvitamin D. Biotin interference can produce both falsely normal and falsely abnormal results. In the US, biotin as a non-prescription dietary supplement is sold in amounts of 1 to 10 mg per serving, with claims for supporting hair and nail health, and as 300 mg per day as a possibly effective treatment for multiple sclerosis (see Research). Overconsumption of 5 mg/day or higher causes elevated concentration in plasma that interferes with biotin-streptavidin immunoassays in an unpredictable manner. Healthcare professionals are advised to instruct patients to stop taking biotin supplements for 48 h or even up to weeks before the test, depending on the specific test, dose, and frequency of biotin uptake. Guidance for laboratory staff is proposed to detect and manage biotin interference.
https://en.wikipedia.org/wiki?curid=54118
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During the Battle of White Horse during the 6–15 of October 1952, the 53rd Tank Company, assigned to the 9th Infantry Division, contributed to the victory by bombarding the side of the enemy's offensive force and suppressing heavy weapons deployed on the enemy-occupied highlands. In the Battle of Betty Hill on 15–16 July 1953, the 57th Tank Company of the 3rd Tank Battalion provided direct fire support for a platoon defending the highlands overnight, which claimed the lives of 300 communist soldiers. However, the M36 had limitations for large-scale operations due to the equipment already being retired from the U.S. military. Spare parts were always insufficient, and it was difficult to obtain fully functional vehicles for the additional construction of the armored unit. In addition, servicing the vehicle became even harder because each unit was too scattered around infantry units. Therefore, the Korean Army began operating in large numbers, forming 3 armored battalions in early 1953.
https://en.wikipedia.org/wiki?curid=947388
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"Scutosaurus" comes from the Salarevskaya Formation, which has a uniformly red coloration and comprises paleosol horizons, which deposit in cyclically shallow-water and dry area. The paleosol horizons are highly variable in shape and size throughout the formation, which may mean they came from different sources (polygenic). Paleosols gradually disappear in the upper part of the formation where the thickness of beds becomes much more discontinuous as well as irregular (from some millimeters to several meters), and the appearance of blue spots which may represent the accumulation of reduced iron oxides. These beds are capped off by a carbonate shell, varying from a small knot to up to a meter (3.3 ft) thick. The paleosols and shells feature holes left behind by plant roots, but these are absent in the clay-siltstone breccias and sand lenses. The formation has typically been explained as the result of several catastrophic floods washing over arid to semi-arid plains during wet seasons, featuring several temporarily filled channels and permanently dry lakes.
https://en.wikipedia.org/wiki?curid=4462232
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As of Fall 2019, there were 24,485 undergraduate students and 8,333 graduate students, for an enrollment total of 32,818, making it the second largest public university in the state after Utah Valley University. Graduate studies include the S.J. Quinney College of Law and the School of Medicine, Utah's first medical school. It is a member of the Association of American Universities (AAU) and is classified among "R1: Doctoral Universities – Very high research activity". According to the National Science Foundation, the university received $552 million in research and development funding in 2018, ranking it 45th in the nation. In addition, the university's Honors College has been reviewed among 100 leading national Honors Colleges in the U.S. The university's health care system includes four hospitals, including the University of Utah Hospital and Huntsman Cancer Institute, along with twelve community clinics and specialty centers such as the Moran Eye Center. The university's athletic teams, the Utes, participate in NCAA Division I athletics (FBS for football) as a member of the Pac-12 Conference.
https://en.wikipedia.org/wiki?curid=32097
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Concentrations of PAHs in river and estuarine sediments vary according to a variety of factors including proximity to municipal and industrial discharge points, wind direction and distance from major urban roadways, as well as tidal regime which controls the diluting effect of generally cleaner marine sediments relative to freshwater discharge. Consequently, the concentrations of pollutants in estuaries tends to decrease at the river mouth. Understanding of sediment hosted PAHs in estuaries is important for the protection of commercial fisheries (such as mussels) and general environmental habitat conservation because PAHs can impact the health of suspension and sediment feeding organism. River-estuary surface sediments in the UK tend to have a lower PAH content than sediments buried 10–60 cm from the surface reflecting lower present day industrial activity combined with improvement in environmental legislation of PAH. Typical PAH concentrations in UK estuaries range from about 19 to 16,163 µg/kg (dry sediment weight) in the River Clyde and 626 to 3,766 µg/kg in the River Mersey. In general estuarine sediments with a higher natural total organic carbon content (TOC) tend to accumulate PAHs due to high sorption capacity of organic matter. A similar correspondence between PAHs and TOC has also been observed in the sediments of tropical mangroves located on the coast of southern China.
https://en.wikipedia.org/wiki?curid=653006
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Five years later, Piccolo teams up with Goku to defeat his older brother Raditz. Piccolo is able to defeat Raditz, but at the cost of Goku's life, as Piccolo's move "Makankōsappō" cuts through both Saiyans. Piccolo's subsequent conversation with the dying Raditz, in which he reveals that the Dragon Balls can resurrect, is broadcast. Piccolo remains amazed with the powers from Gohan and trains him in preparation to fight against the two Saiyans who will invade Earth. As the year goes by, Piccolo starts to change as he spends time training Gohan, slowly beginning to bond with him. When the Saiyans arrive a year later, Piccolo discovers his heritage from the planet Namek. In the fight against Nappa, Piccolo sacrifices himself to protect Gohan from the attack, resulting in the deaths of both himself and Kami. After the Saiyans are defeated, Gohan and the survivors travel to Piccolo's homeworld, Namek, to revive those who died against the Saiyans with the Namekian Dragon Balls. In the meantime, Piccolo trains in the afterlife with Kaiō-sama. Piccolo is resurrected on planet Namek to help Goku and others defeat the evil Frieza. He takes this time to merge with the beaten Namekian called Nail, giving Piccolo a power increase. Despite his massive power increase and going head-to-head with Frieza's second transformation, However, the plan fails as Frieza reveals the full extent of his powers. In Frieza's following fight with Goku, who tries charging a "Genki-dama" to defeat him, Piccolo assists him alongside Gohan and Krillin. Once Frieza emerges from the impact of the "Genki-dama" unscathed, Piccolo is severely injured by Frieza with a shot to the chest. Piccolo is later teleported off the planet to safety on Earth and, after regaining consciousness, declines to return to a new version of Namek as he wishes to protect Gohan and become stronger while remaining on Earth.
https://en.wikipedia.org/wiki?curid=262049
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Adaptations are produced incrementally through natural selection, so major phenotypic changes will not usually spread within populations if they decrease the fitness of individuals. Although neutral changes (ones which provide no benefit) can spread through genetic drift, and detrimental changes can spread under some circumstances, large changes that require multiple steps will occur only if the intermediate stages increase fitness. Richard Dawkins describes the matter: "The wheel may be one of those cases where the engineering solution can be seen in plain view, yet be unattainable in evolution because it lies [on] the other side of a deep valley, cutting unbridgeably across the massif of Mount Improbable." In such a fitness landscape, wheels might sit on a highly favorable "peak", but the valley around that peak may be too deep or wide for the gene pool to migrate across by genetic drift or natural selection. Stephen Jay Gould notes that biological adaptation is limited to working with available components, commenting that "wheels work well, but animals are debarred from building them by structural constraints inherited as an evolutionary legacy".
https://en.wikipedia.org/wiki?curid=19995454
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In a analysis of their data, scientists of the OPERA collaboration reported evidence that neutrinos they produced at CERN in Geneva and recorded at the OPERA detector at Gran Sasso, Italy, had traveled faster than light. The neutrinos were calculated to have arrived approximately 60.7 nanoseconds (60.7 billionths of a second) sooner than light would have if traversing the same distance in a vacuum. After six months of cross checking, on , the researchers announced that neutrinos had been observed traveling at faster-than-light speed. Similar results were obtained using higher-energy (28 GeV) neutrinos, which were observed to check if neutrinos' velocity depended on their energy. The particles were measured arriving at the detector faster than light by approximately one part per 40,000, with a 0.2-in-a-million chance of the result being a false positive, "assuming" the error were entirely due to random effects (significance of six sigma). This measure included estimates for both errors in measuring and errors from the statistical procedure used. It was, however, a measure of precision, not accuracy, which could be influenced by elements such as incorrect computations or wrong readouts of instruments. For particle physics experiments involving collision data, the standard for a discovery announcement is a five-sigma error limit, looser than the observed six-sigma limit.
https://en.wikipedia.org/wiki?curid=33338392
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In March 2004, the Wolf Pack Men's basketball team qualified for the NCAA tournament and advanced to the Sweet Sixteen for the first time in school history. The team earned a repeat trip in 2005 and beat Texas in the first round before falling to eventual national runner-up Illinois. The team returned for 2006 as a No. 5 seed but was upset in the first round by former Big Sky Conference rival Montana. They began the 2006–07 season ranked #24. The Pack's major star during this recent period of success was Nick Fazekas. In 2007, Nevada was ranked No. 9 in men's basketball, which is the highest ranking that Nevada has ever held. Coach Mark Fox took over after Trent Johnson left in 2004 to coach at Stanford University. On April 3, 2009, it was announced that David Carter would replace Fox who decided to leave Nevada for the same position at the University of Georgia.
https://en.wikipedia.org/wiki?curid=239274
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In 1846, the natural history lectures of Louis Agassiz were acclaimed both in New York and on his campus at Harvard College. Agassiz's approach was distinctly idealist and posited Americans' "participation in the Divine Nature" and the possibility of understanding "intellectual existences". Agassiz's perspective on science combined observation with intuition and the assumption that one can grasp the "divine plan" in all phenomena. When it came to explaining life-forms, Agassiz resorted to matters of shape based on a presumed archetype for his evidence. This dual view of knowledge was in concert with the teachings of Common Sense Realism derived from Scottish philosophers Thomas Reid and Dugald Stewart, whose works were part of the Harvard curriculum at the time. The popularity of Agassiz's efforts to "soar with Plato" probably also derived from other writings to which Harvard students were exposed, including Platonic treatises by Ralph Cudworth, John Norris and in a Romantic vein Samuel Coleridge. The library records at Harvard reveal that the writings of Plato and his early modern and Romantic followers were almost as regularly read during the 19th century as those of the "official philosophy" of the more empirical and more deistic Scottish school.
https://en.wikipedia.org/wiki?curid=4484508
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With these detectors, images can be captured with much higher contrast than with the CCD cameras previously used and have led to amazing progress in structural biology. By investing in this new technology, CEF members have been able to speed up structure determination and also solve the structures of macromolecular complexes that were not amenable to x-ray crystallography studies. Another focus of CEFs electron microscopists was to reveal the macromolecular organisation of living cells by means of cryo-electron tomography. Cryo-ET is the only technique that can obtain molecular resolution images of intact cells in a quasi-native environment. Such tomograms contain a large amount of information as they are essentially a three-dimensional map of the cellular proteome and depict the whole network of macromolecular interactions. Information-mining algorithms exploit structural data from various techniques, identify distinct macromolecules and computationally fit atomic resolution structures in the cellular tomograms, thereby bridging the resolution gap.
https://en.wikipedia.org/wiki?curid=63334526
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The flatness problem is naturally solved by the Einstein–Cartan–Sciama–Kibble theory of gravity, without an exotic form of matter required in inflationary theory. This theory extends general relativity by removing a constraint of the symmetry of the affine connection and regarding its antisymmetric part, the torsion tensor, as a dynamical variable. It has no free parameters. Including torsion gives the correct conservation law for the total (orbital plus intrinsic) angular momentum of matter in the presence of gravity. The minimal coupling between torsion and Dirac spinors obeying the nonlinear Dirac equation generates a spin-spin interaction which is significant in fermionic matter at extremely high densities. Such an interaction averts the unphysical big bang singularity, replacing it with a bounce at a finite minimum scale factor, before which the Universe was contracting. The rapid expansion immediately after the big bounce explains why the present Universe at largest scales appears spatially flat, homogeneous and isotropic. As the density of the Universe decreases, the effects of torsion weaken and the Universe smoothly enters the radiation-dominated era.
https://en.wikipedia.org/wiki?curid=1118171
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Human skin is the first line of defense against many pathogens and can itself be subject to a variety of diseases and issues, such as cancers and inflammation. As such, skin-on-a-chip (SoC) applications include testing of topical pharmaceuticals and cosmetics, studying the pathology of skin diseases and inflammation, and "creating noninvasive automated cellular assays" to test for the presence of antigens or antibodies that could denote the presence of a pathogen. Despite the wide variety of potential applications, relatively little research has gone into developing a skin-on-a-chip compared to many other organ-on-a-chips, such as lungs and kidneys. Issues such as detachment of the collagen scaffolding from microchannels, incomplete cellular differentiation, and predominant use of poly(dimethysiloxane) (PDMS) for device fabrication, which has been shown to leach chemicals into biological samples and cannot be mass-produced stymie standardization of a platform. One additional difficulty is the variability of cell-culture scaffolding, or the base substance in which to culture cells, that is used in skin-on-chip devices. In the human body, this substance is known as the extracellular matrix.
https://en.wikipedia.org/wiki?curid=33980770
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Unlike cold welding process at macro-scale which normally requires large applied pressures, scientists discovered that single-crystalline ultrathin gold nanowires (diameters less than 10 nm) can be cold-welded together within seconds by mechanical contact alone, and under remarkably low applied pressures. High-resolution transmission electron microscopy and in-situ measurements reveal that the welds are nearly perfect, with the same crystal orientation, strength and electrical conductivity as the rest of the nanowire. The high quality of the welds is attributed to the nanoscale sample dimensions, oriented-attachment mechanisms and mechanically assisted fast surface diffusion. Nanoscale welds were also demonstrated between gold and silver, and silver and silver, indicating that the phenomenon may be generally applicable and therefore offer an atomistic view of the initial stages of macroscopic cold welding for either bulk metals or metallic thin film.
https://en.wikipedia.org/wiki?curid=495733
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The Impression 5 Science Center was founded by Marilynne Eichinger in her basement in Lansing, Michigan, in 1972. Eichinger graduated with a BA in sociology/anthropology from Boston University and an MA in counseling psychology from Michigan State University. As a mother of five she was influenced by the Montessori education her children received as well as the writings of Jean Piaget and Howard Gardner. Much of her life was surrounded by family and friends involved in physics and engineering and Eichinger became interested in developing a way to explain scientific principles that appeared so complex in a way that the general public could understand. She promoted the design and development of hands-on exhibits that challenged visitors thinking processes. The initial goal of Impression 5 was to develop fun, educational exhibits that focused on the five senses. A variety of approaches was offered to take into account individual learning styles.
https://en.wikipedia.org/wiki?curid=28344109
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A plan to merge six of the current PASSHE institutions into two multi-campus universities is ongoing as of July 2021. There was huge public outcry against the plan. As it faced opposition by the Lock Haven City Council, the Clinton County Commissioners, the Clear Coalition, the Party for Socialism and Liberation Chester County, PASSHE Defenders, AFSCME Council 13, Pennsylvania AFL-CIO, APSCUF and a slew of public comments. Groups like APSCUF, AFSCME, and the Pennsylvania AFL-CIO held a press conference May 3, 2021 to speak out in opposition to the consolidation. PASSHE Defenders & the Party for Socialism & Liberation Chester County held rallies across the state at the campuses slated for consolidation and at the state capital Harrisburg. The plan being a part of the larger state system redesign was shown to have disastrous effects according to a report out of the Political Economy Research Institute (PERI) of the University of Massachusetts Amherst. The report titled "The Economic Impact of the PASSHE Employment Reductions" outlines "[The] large cuts in staffing, both of faculty and of professional and classified staff in good unionized jobs, constitute the core of the restructuring. The cuts, amounting to 14 percent of overall PASSHE employment, are of a magnitude equivalent to the largest private-sector plant closings and mass layoffs of the previous decade in Pennsylvania."
https://en.wikipedia.org/wiki?curid=1357781
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France was the chief enemy until the defeat of Napoleon in 1815. It had a much larger population and a more powerful army, but a weaker navy. The British were generally successful in their many wars. The notable exception, the American War of Independence (1775–1783), saw Britain, without any major allies, defeated by the American colonials who had the support of France, the Netherlands and (indirectly) Spain. A favoured British diplomatic strategy involved subsidising the armies of continental allies (such as Prussia), thereby turning London's enormous financial power to military advantage. Britain relied heavily on its Royal Navy for security, seeking to keep it the most powerful fleet afloat, eventually with a full complement of bases across the globe. British dominance of the seas was vital to the formation and maintaining of the British Empire, which was achieved through the support of a navy larger than the next two largest navies combined, prior to 1920. The British generally stood alone until the early 20th century, when it became friendly with the U.S. and made alliances with Japan, France and Russia. Germany was now the main antagonist.
https://en.wikipedia.org/wiki?curid=31731
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The most desirable finish surface for a composite resin can be provided by aluminum oxide disks. Classically, Class III composite preparations were required to have retention points placed entirely in dentin. A syringe was used for placing composite resin because the possibility of trapping air in a restoration was minimized. Modern techniques vary, but conventional wisdom states that because there have been great increases in bonding strength due to the use of dentin primers in the late 1990s, physical retention is not needed except for the most extreme of cases. Primers allow the dentin's collagen fibers to be "sandwiched" into the resin, resulting in a superior physical and chemical bond of the filling to the tooth. Indeed, composite usage was highly controversial in the dental field until primer technology was standardized in the mid to late 1990s. The enamel margin of a composite resin preparation should be beveled in order to improve the appearance and expose the ends of the enamel rods for acid attack. The correct technique of enamel etching prior to placement of a composite resin restoration includes etching with 30%-50% phosphoric acid and rinsing thoroughly with water and drying with air only. In preparing a cavity for restoration with composite resin combined with an acid etch technique, all enamel cavosurface angles should be obtuse angles. Contraindications for composite include varnish and zinc oxide-eugenol. Composite resins for Class II restorations were not indicated because of excessive occlusal wear in the 1980s and early 1990s. Modern bonding techniques and the increasing unpopularity of amalgam filling material have made composites more attractive for Class II restorations. Opinions vary, but composite is regarded as having adequate longevity and wear characteristics to be used for permanent Class II restorations. Whether composite materials last as long or have similar leakage and sensitivity properties when compared to Class II amalgam restorations was described as a matter of debate in 2008.<ref name="DOI10.4103/0972-0707.45247"></ref>
https://en.wikipedia.org/wiki?curid=1881464
877,749
1,852,013
By 1850, three British rescue attempts had already failed to locate Franklin. In April and December 1849, Lady Jane Franklin sent appeals to American President Zachary Taylor that the search continue. When Congress lingered in passing the appropriations to purchase vessels, American merchant Henry Grinnell purchased two brigs, the 91-ton and 144-ton , refitted them for Arctic service and offered them to the government, who quickly provided additional funds and volunteer Naval officers and crew. The expedition was instructed to focus on the areas of the Wellington Channel and Cape Walker as conditions permitted. Elisha Kent Kane was brought in from field work in Florida to serve as surgeon aboard the "Advance", and Captain Donald Manson was brought on as ice master aboard the "Sophia". Preparation was managed quickly, and the expedition set out on May 22, 1850, from the Navy Yard at New York.
https://en.wikipedia.org/wiki?curid=26501694
1,850,952
93,487
Typically operated from small aircraft carriers, large amphibious assault ships and simple forward operating bases, AV-8Bs have participated in numerous military and humanitarian operations, proving themselves versatile assets. U.S. Army General Norman Schwarzkopf named the USMC Harrier II as one of several important weapons in the Gulf War. It has also served in Operation Enduring Freedom in Afghanistan since 2001, the Iraq War since 2003, and was used in Operation Odyssey Dawn in Libya in 2011. Italian and Spanish Harrier IIs have taken part in overseas conflicts in conjunction with NATO coalitions. During its service history, the AV-8B has had a high accident rate, related to the percentage of time spent in critical take-off and landing phases. USMC and Italian Navy AV-8Bs are being replaced by the Lockheed Martin F-35B Lightning II, with the former expected to operate its Harriers until 2025.
https://en.wikipedia.org/wiki?curid=18940560
93,446
66,439
One of the earliest recorded outbreaks of foodborne botulism occurred in 1793 in the village of Wildbad in what is now Baden-Württemberg, Germany. Thirteen people became sick and six died after eating pork stomach filled with blood sausage, a local delicacy. Additional cases of fatal food poisoning in Württemberg led the authorities to issue a public warning against consuming smoked blood sausages in 1802 and to collect case reports of "sausage poisoning". Between 1817 and 1822, the German physician Justinus Kerner published the first complete description of the symptoms of botulism, based on extensive clinical observations and animal experiments. He concluded that the toxin develops in bad sausages under anaerobic conditions, is a biological substance, acts on the nervous system, and is lethal even in small amounts. Kerner hypothesized that this "sausage toxin" could be used to treat a variety of diseases caused by an overactive nervous system, making him the first to suggest that it could be used therapeutically. In 1870, the German physician Müller coined the term "botulism" to describe the disease caused by sausage poisoning, from the Latin word "botulus", meaning "sausage".
https://en.wikipedia.org/wiki?curid=40172
66,414
903,685
The M107's combat experience with the US military was almost entirely limited to the Vietnam War. The Vietnamese words "Sấm Sét" ("Lightning") and "Vua Chiến Trường" ("King of the Battlefield") were often painted on the guns to commemorate its sheer firepower. There, it proved its effectiveness by having one of the longest ranges of any mobile artillery-piece operated during that theater of combat in the Cold War, outranging the Soviet 130mm M46 heavy field-guns employed by the People's Army of Vietnam (PAVN). Maximum range with M437A2 or M437A1 projectile is approximately 32,800 m. This long-range advantage, along with its ability to rapidly move from its previous position, made it an effective weapon for destroying North Vietnamese Army and Viet Cong command-and-control sites, communications facilities and supply-columns, while evading counter-battery fire from its Soviet counterparts in service with North Vietnam. This was proven in 1968 at the Battle of Khe Sanh, where American forces came under a long and intense siege by North Vietnamese troops and were constantly bombarded by accompanying artillery fire.
https://en.wikipedia.org/wiki?curid=2681976
903,209
258,064
When Ronald Reagan took office, Laxalt's close ties with Reagan proved useful. Reagan canceled the new shelter system in 1981, calling it "a Rube Goldberg scheme". On 2 October 1981 he proposed deploying an initial force of missiles in the approximately 60 existing Titan II silos, removing those now outdated missiles from service. The silos would be modified for much greater strength, and a number of Minuteman III silos similarly adapted over time to bring the force to a total of 100 missiles. Additionally, he suggested funding development of three additional concepts, airborne drops from cargo aircraft, an "active defense" using short-range anti-ballistic missile, or basing new silos deep underground or on the south side of mesas ("reverse-inclination basing"). The latter two quickly proved unacceptable for various reasons, while testing of the air-drop concept was pursued.
https://en.wikipedia.org/wiki?curid=201975
257,930
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The goal of the Global Virome Project (GVP) is to identify and prevent future virus outbreaks. The GVP is centered on the massive collection and sequencing of the planet’s unknown viruses, with an estimated 1.6 million viral species yet to be discovered in mammal and bird populations. Of these, 631,000 to 827,000 have zoonotic potential. The cost of identifying these unidentified viruses is a major limitation of the GVP, with a total cost estimate of $1.2 billion. That being said, preventing an outbreak is still less costly than reacting to one, with the total estimated cost of the ongoing COVID-19 pandemic estimated at more than $16 trillion. The Global Virome project also aims to boost infectious disease surveillance around the globe by using low cost sequencing methods in high risk countries to prevent disease outbreaks by expanding on the efforts of the USAID (agency for international development) EPT (Emerging Pandemic Threats) PREDICT project. The PREDICT project was founded to discover unidentified viral species by sampling animals and humans in countries with high zoonotic disease threat and determine the mechanisms that cause viral spillover into human populations. The Predict project found over 1000 unique viruses in animals and humans.
https://en.wikipedia.org/wiki?curid=40951831
1,564,396
718,891
Wilfred Bion was a potent and original contributor to psychoanalysis. He was one of the first to analyse patients in psychotic states using an unmodified analytic technique; he extended existing theories of projective processes and developed new conceptual tools. The degree of collaboration between Hanna Segal, Wilfred Bion and Herbert Rosenfeld in their work with psychotic patients during the late 1950s, and their discussions with Melanie Klein at the time, means that it is not always possible to distinguish their exact individual contributions to the developing theory of splitting, projective identification, unconscious phantasy and the use of countertransference. As Donald Meltzer (1979, 1981), Denis Carpy (1989, p. 287), and Michael Feldman (2009, pp. 33, 42) have pointed out, these three pioneering analysts not only sustained Klein's clinical and theoretical approach, but through an extension of the concept of projective identification and countertransference they deepened and expanded it. In Bion's clinical work and supervision the goal remains insightful understanding of psychic reality through a disciplined experiencing of the transference–countertransference, in a way that promotes the growth of the whole personality.
https://en.wikipedia.org/wiki?curid=44779
718,511
1,648,404
To reflect changes in conditions, a revised Long Range Development Plan was prepared in 1962 under the direction of an expanded Campus Planning Committee headed successively by Chancellors Glenn T. Seaborg and Edward Strong. In addition to Wurster, the committee included Consulting Landscape Architect Thomas Church, Campus Architect Louis A. DeMonte of the Office of Architects and Engineers and four other university officials. The new plan related to the California Master Plan for Higher Education of 1960, which established the roles of the public junior colleges, state college system, and the University of California, and the subsequent University Growth Plan prepared by President Clark Kerr to guide academic development of the university. Enrollment levels were established with a maximum at Berkeley of 27,500 projected for the mid-1960s. The revised plan also included the use of Strawberry Canyon and the hill area, as well as outlying campus properties not previously considered, and incorporated several landscaping proposals prepared by Church for the central campus, most notably the Springer Memorial Gateway on the west side and the landscaping for Wurster Hall.
https://en.wikipedia.org/wiki?curid=4486944
1,647,472
1,940,741
The MIQE guidelines were created due to the low quality of qPCR data submitted to academic journals at the time, which was only becoming more common as Next Generation Sequencing machinery allowed for such experiments to be run for a cheaper cost. Because the technique is utilized across all of science in multiple fields, the instruments, methods, and designs of how qPCR is used differs greatly. To help improve overall quality, the MIQE guidelines were made as generalized suggestions on basic experimental procedures and forms of data that should be collected as a minimum level of reported information for other researchers to understand and use when reading the published material. Setting up a recognized and largely agreed upon set of guidelines such as these was deemed important by the scientific community especially due to the ever increasing amount of scientific work coming from developing countries with many different languages and protocols.
https://en.wikipedia.org/wiki?curid=60996879
1,939,630
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One needs to consider the computational cost of "ab initio" methods when determining whether they are appropriate for the problem at hand. When compared to much less accurate approaches, such as molecular mechanics, "ab initio" methods often take larger amounts of computer time, memory, and disk space, though, with modern advances in computer science and technology such considerations are becoming less of an issue. The Hartree-Fock (HF) method scales nominally as "N" ("N" being a relative measure of the system size, not the number of basis functions) – e.g., if one doubles the number of electrons and the number of basis functions (double the system size), the calculation will take 16 (2) times as long per iteration. However, in practice it can scale closer to "N" as the program can identify zero and extremely small integrals and neglect them. Correlated calculations scale less favorably, though their accuracy is usually greater, which is the trade off one needs to consider. One popular method is Møller–Plesset perturbation theory (MP). To second order (MP2), MP scales as "N". To third order (MP3) MP scales as "N". To fourth order (MP4) MP scales as "N". Another method, coupled cluster with singles and doubles (CCSD), scales as "N" and extensions, CCSD(T) and CR-CC(2,3), scale as "N" with one noniterative step which scales as "N". Hybrid Density functional theory (DFT) methods using functionals which include Hartree–Fock exchange scale in a similar manner to Hartree–Fock but with a larger proportionality term and are thus more expensive than an equivalent Hartree–Fock calculation. Local DFT methods that do not include Hartree–Fock exchange can scale better than Hartree–Fock.
https://en.wikipedia.org/wiki?curid=4683300
528,651
1,734,440
The Purbeck Limestone Group is a succession of limestones, shales, and clays named after the Isle of Purbeck, laid down mainly in very shallow lagoons and freshwater lakes, with only occasional marine influence at the lower levels where halite, gypsum, and other evaporites are found. The muddled sediments around Lulworth are thought to be caused by a thick layer of these evaporites dissolving. Evidence also exists of uplift and erosion of earlier formations. The climate around this time had changed from a tropical to a subtropical one, with pronounced wet and dry seasons as indicated by the growth rings in the fossilised trees also found in the lower levels of the Purbeck strata. These trees grew around the low coastal areas and were, from time to time, subjected to drowning from the sea. The fallen trees and their stumps became covered by stromatolites which trapped sediments. The limestones at this level, which vary greatly in colour, are composed of densely packed shells of the freshwater snail "Viviparus". Their ability to take a very high polish has led them to become known as Purbeck Marble. Like the older Forest Marble, it is a sedimentary marble rather than a true metamorphic one.
https://en.wikipedia.org/wiki?curid=1121663
1,733,463
926,543
In August 1961, the Soviet Union ended the nuclear test moratorium that had been in place since November 1958, so Kennedy resumed US nuclear weapons testing in September. With a second crash program at the Nevada Test site, labor became scarce, and there was a strike. When that ended, the workers had to come to grips with the difficulties of dealing with hydrogen, which could leak through microscopic holes that were too small for other fluids to pass through. On 7 November 1961, a minor accident caused a violent hydrogen release. The complex finally became operational in 1964. SNPO envisaged the construction of a 20,000 MW nuclear rocket engine, so Boyer had the Chicago Bridge & Iron Company construct two gigantic cryogenic storage dewars. An engine maintenance and disassembly building (E-MAD) was added. It had thick concrete walls and shield bays where engines could be assembled and disassembled. There was also an engine test stand (ETS-1); two more were planned.
https://en.wikipedia.org/wiki?curid=712716
926,057
995,557
The two parchment documents were turned over to the Library of Congress by executive order, and in 1924 President Calvin Coolidge dedicated the bronze-and-marble shrine for public display of the Constitution in the main building. The parchments were laid over moisture absorbing cellulose paper, vacuum-sealed between double panes of insulated plate glass, and protected from light by a gelatin film. Although building construction of the Archives Building was completed in 1935, in December 1941 they were moved from the Library of Congress until September 1944, and stored at the U.S. Bullion Depository, Fort Knox, Kentucky, along with the Declaration of Independence and the Gettysburg Address. In 1951 following a study by the National Bureau of Standards to protect from atmosphere, insects, mold and light, the parchments were re-encased with special light filters, inert helium gas and proper humidity. They were transferred to the National Archives and Records Administration in 1952.
https://en.wikipedia.org/wiki?curid=497752
995,040
1,510,166
The significance of SPD was known from the ancient times, at least during the transition from the Bronze Age to the Iron Age, when repeated hammering and folding was employed for processing strategic tools such as swords. The development of the principles underlying SPD techniques goes back to the pioneering work of P.W. Bridgman at Harvard University in the 1930s. This work concerned the effects on solids of combining large hydrostatic pressures with concurrent shear deformation and it led to the award of the Nobel Prize in Physics in 1946. Very successful early implementations of these principles, described in more detail below, are the processes of equal-channel angular pressing (ECAP) developed by V.M. Segal and co-workers in Minsk in the 1970s and high-pressure torsion, derived from Bridgman's work, but not widely developed until the 1980s at the Russian Institute of Metals Physics in modern-day Yekaterinburg.
https://en.wikipedia.org/wiki?curid=23756855
1,509,316
2,208,008
Stylidium oviflorum is a dicotyledonous plant that belongs to the genus "Stylidium" (family Stylidiaceae). The specific epithet "oviflorum" comes from the Latin "ovi" meaning egg and "florus" meaning flower, which refers to this species flower colouration that resembles a fried egg with bright yellow and pure white colours. It is an annual plant that grows from 6 to 26 cm tall. The linear or deltate leaves, about 3-11 per plant, are scattered along the stem and are generally 1.4–3 mm long and 0.25-0.6 mm wide. Petioles and scapes are absent. Inflorescences are 4–15 cm long and produce white and yellow flowers that bloom from April to August in the southern hemisphere. "S. oviflorum" is endemic to the northern area of Queensland from Mareeba and Wairuna west to Barwidgi. Its habitat is recorded as being sandy soils in seepage areas, on hillsides, or beside creeks in the company of "Melaleuca viridiflora", "Eucalyptus camaldulensis", or "E. cullenii". "S. oviflorum" is most closely related to "S. fissilobum" but differs mostly in the corolla colour and self-supporting stems. Its conservation status has been assessed as data deficient.
https://en.wikipedia.org/wiki?curid=12266484
2,206,750
1,787,778
Goldsmith started her academic career at the California Institute of Technology and was there for four years. She joined Stanford in 1999, becoming an associate professor in 2002 and a full professor in 2007. At Stanford, she has served as chair of the faculty senate, and on the school's task force on women and leadership. In 2006, she took a leave of absence from Stanford and co-founded Quantenna Communications, a company that produces silicon chipsets designed for high-speed, wireless high-definition video home networking. She served as chief technology officer of the startup until returning to Stanford in 2008. She was also a founder and CTO of Plume WiFi, which was founded in 2014 and develops WiFi technology. She joined Princeton in 2020 as Dean of Engineering and Applied Science at a pivotal time, where it is expected to grow its engineering faculty by 50%, build a new neighborhood with new buildings for all engineering departments and interdisciplinary institutes, and foster significantly more innovation, entrepreneurship, and partnerships with industry.
https://en.wikipedia.org/wiki?curid=55909465
1,786,773
1,473,815
Räikkonen disliked the situation he found himself in during the race by making three pit stops, complaining of heavy front tyre degradation and excess understeer. He said neither he or Ferrari identified the source of the problem but appreciated assistance: "To try and drive slowly in certain places didn't make any difference so I don't understand it really. Wherever we finished it's pretty disappointing. Not being able to solve certain issues is frustrating. Hopefully something comes up and we find what the issues are." Similarly, Alonso complained his car had severe tyre vibrations in the final two laps, reducing his visibility: "I tried to control the pace. I was asking for a gap from behind to cross the line just in front of them. But then Vettel overtook [Kevin] Magnussen and there was no time to save any more so on the last lap I was flat out with huge vibrations." The Williams performance chief Rob Smedley suspected minor issues such as Massa's slow pit stop prevented his team from finishing on the podium. Red Bull team principal Christian Horner said Vettel's first lap pit stop for the medium tyres was done with the intention of not using soft tyres for the rest of the race.
https://en.wikipedia.org/wiki?curid=38847467
1,472,984
1,192,069
Surgeons have used the concept of damage control surgery for years, and controlling hemorrhage with packing is over a century old. Pringle described this technique in patients with substantial hepatic trauma in the early twentieth century. The U.S. military did not encourage this technique during World War II and the Vietnam War. Lucas and Ledgerwood described the principle in a series of patients. Subsequent studies were repeated by Feliciano and colleagues, and they found that hepatic packing increased survival by 90%. This technique was then specifically linked to patients who were hemorrhaging, hypothermic, and coagulopathic. This extrapolation allowed for the first article in 1993 by Rotondo and Schwab specifically adapting the term “damage control”. This term was taken from the United States Navy who initially used the term as “the capacity of a ship to absorb damage and maintain mission integrity” (DOD 1996). This was the first article that brought together the concept of limiting operative time in these critically ill patients to allow for reversal of physiologic insults to improve survival. In addition, the description illustrated how the three phases of damage control surgery can be implemented. Since this description the development of this concept has grown both within the trauma community and beyond.
https://en.wikipedia.org/wiki?curid=36643113
1,191,433
293,024
Photovoltaic systems need to be monitored to detect breakdown and optimize operation. There are several photovoltaic monitoring strategies depending on the output of the installation and its nature. Monitoring can be performed on site or remotely. It can measure production only, retrieve all the data from the inverter or retrieve all of the data from the communicating equipment (probes, meters, etc.). Monitoring tools can be dedicated to supervision only or offer additional functions. Individual inverters and battery charge controllers may include monitoring using manufacturer specific protocols and software. Energy metering of an inverter may be of limited accuracy and not suitable for revenue metering purposes. A third-party data acquisition system can monitor multiple inverters, using the inverter manufacturer's protocols, and also acquire weather-related information. Independent smart meters may measure the total energy production of a PV array system. Separate measures such as satellite image analysis or a solar radiation meter (a pyranometer) can be used to estimate total insolation for comparison.
https://en.wikipedia.org/wiki?curid=15677755
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Chemical reactions led to the first self-replicating molecules about four billion years ago. A half billion years later, the last common ancestor of all current life arose. The evolution of photosynthesis allowed the Sun's energy to be harvested directly by life forms. The resultant molecular oxygen () accumulated in the atmosphere and due to interaction with ultraviolet solar radiation, formed a protective ozone layer () in the upper atmosphere. The incorporation of smaller cells within larger ones resulted in the development of complex cells called eukaryotes. True multicellular organisms formed as cells within colonies became increasingly specialized. Aided by the absorption of harmful ultraviolet radiation by the ozone layer, life colonized Earth's surface. Among the earliest fossil evidence for life is microbial mat fossils found in 3.48 billion-year-old sandstone in Western Australia, biogenic graphite found in 3.7 billion-year-old metasedimentary rocks in Western Greenland, and remains of biotic material found in 4.1 billion-year-old rocks in Western Australia. The earliest direct evidence of life on Earth is contained in 3.45 billion-year-old Australian rocks showing fossils of microorganisms.
https://en.wikipedia.org/wiki?curid=9228
832
162,186
The policy of nationalising the coal mines had been accepted in principle by owners and miners alike before the elections of 1945. The owners were paid £165,000,000. The government set up the National Coal Board to manage the coal mines; and it loaned it £150,000,000 to modernise the system. The general condition of the coal industry had been unsatisfactory for many years, with poor productivity. In 1945, there were 28% more workers in the coal mines than in 1890, but the annual output was only 8% greater. Young people avoided the pits; between 1931 and 1945 the percentage of miners more than 40 years old rose from 35% to 43%, and 24,000 over 65 years old. The number of surface workers decreased between 1938 and 1945 by only 3,200, but in that same time the number of underground workers declined by 69,600, substantially altering the balance of labour in the mines. That accidents, breakdowns, and repairs in the mines were nearly twice as costly in terms of production in 1945 as they had been in 1939 was probably a by-product of the war. Output in 1946 averaged 3,300,000 tons weekly. By summer 1946 it was clear that the country was facing a coal shortage for the upcoming winter with stock piles of 5 million tons too low. Nationalisation exposed both a lack of preparation for public ownership and a failure to stabilize the industry in advance of the change. Also lacking were any significant incentives to maintain or increase coal production to meet demand.
https://en.wikipedia.org/wiki?curid=33643110
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Another unique feature of the Roman infantry was the depth of its spacing. Most ancient armies deployed in shallower formations which might deepen their ranks heavily to add both stamina and shock powerbut their general approach still favoured one massive line, as opposed to the deep Roman arrangement. The advantage of the Roman system is that it allowed the continual funneling or metering of combat power forward over a longer periodmassive, steadily renewed pressure to the frontuntil the enemy broke. Deployment of the second and third lines required careful consideration by the Roman commander. Deployed too early, they might get entangled in the frontal fighting and become exhausted. Deployed too late, they might be swept away in a rout if the first line began to break. Tight control had to be maintained, hence the 3rd line "triarii" were sometimes made to squat or kneel, effectively discouraging premature movement to the front. The Roman commander was thus generally mobile, constantly moving from spot to spot, and often riding back in person to fetch reserves if there was no time for standard messenger service. A large number of officers in the typical Roman army, and the flexible breakdown into sub-units like cohorts or maniples, greatly aided in providing coordination for such moves.
https://en.wikipedia.org/wiki?curid=30855309
762,719
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The concentrations of gold nanoparticles in biological systems for practical usage range from 1-100 nanoparticles per cell. High concentrations may lead to adverse effects for cell structure and function, which may not appear non-toxic in assays but preparation of the particles have been found to produce abnormal effects in the cell. If large concentrations quickly clear the blood vessels, the nanoshells may accumulate in major organs (mainly the liver and spleen). Residual concentrations of these particles were also found in kidneys, lungs, muscle, brain, and bone of mice after 28 days. The concentration of the solution injected intravenously 2.4*10 nanoshells/mL. Even without complete clearance from the system, the nanoshells did not cause any physiological complications in the mice. Su "et al" observed a correlation with the concentration of AuCu and cell damage. Cells were incubated in concentrations of 0.001 and 200 mg mL AuCu. They concluded a 15% cell viability and dose dependent cell damage. Reduction in cell viability was detected in vivo experiments; also related to dosage. Cytotoxicity is not a major concern in the usage of AuNPs, as they localize in the vesicles and cytoplasm as opposed to the nucleus. Thus, no complications spawned due to their aggregation in these parts of the cell.
https://en.wikipedia.org/wiki?curid=46188763
1,784,534
1,008,166
Primary immune thrombocytopenia (ITP) is an acquired immune-mediated disorder characterized by isolated thrombocytopenia, defined as a peripheral blood platelet count less than 100 x 10/L, and the absence of any obvious initiating and/or underlying cause of the thrombocytopenia. Symptoms of ITP include abnormal bleeding and bruising due to the reduction in platelet count. Rh(D) Immune Globulin Intravenous [Human; Anti-D] is indicated for use in non-splenectomized, Rh(D)-positive children with chronic or acute ITP, adults with chronic ITP, and children and adults with ITP secondary to HIV infection. Anti-D must be administered via the intravenous route when used in clinical situations requiring an increase in platelet count. The mechanism of action of anti-D is not fully understood; however, after administration the anti-D coated red blood cell complexes saturate Fcγ receptors sites on macrophages, resulting in preferential destruction of red blood cells (RBCs), therefore sparing antibody-coated platelets. Anti-D is recommended as a first-line therapy for ITP, along with corticosteroids and intravenous immune globulin (IVIG). WinRho SDF is an anti-D manufactured, distributed and marketed by Cangene in the US. There is a black box warning on WinRho SDF due to the risk of potentially fatal intravascular hemolysis when used in the treatment of ITP. Life-threatening anemia, kidney failure, and disseminated intravascular coagulation (DIC) have occurred in people treated with WinRho SDF for ITP.
https://en.wikipedia.org/wiki?curid=3365974
1,007,646
1,636,402
The research projects in the area had started before the construction of the station and included geological research led by the Czech Geological Survey as well as climatological and geomorphological research led by the Masaryk University Faculty of Science. As the construction was nearing completion, the Faculty of Science of the University of South Bohemia in České Budějovice and the Institute of Botany at the Academy of Sciences of the Czech Republic started a joint botanical project of cyanobacteria research. The MU Faculty of Science also prepared a research project focused on ultraviolet radiation in the area; besides UV radiation, the project also studied Ozone layers. The area surrounding the station was also geologically mapped by the Czech Geological Survey. There has been basic ornithological research as well; however, the Nesting season of most birds starts in mid November, while ornithologist usually arrive at the station only at the beginning of January. Ichthyological research focused on fish in coastal waters and their parasites and there was also a study on the Gammarus genus focused on how animals detect the magnetic field. The bacteriological research has described new species of Bacteria. One of the projects assessed the stress of polar researches during their stay at the station and the extent to which their bodies accommodated to the conditions in Antarctica, while another project studied ageing of plastic materials in the extreme Antarctic weather. Institutions from other countries, such as the Instituto Antártico Argentino, Instituto Nacional Antártico Chileno, British Antarctic Survey, Servicio Meteorológico Nacional Argentina, and Nederlands Instituut voor Ecologie also participate in the research. Available spots at the station are offered to researchers and students at both Czech and foreign universities and research institutions.
https://en.wikipedia.org/wiki?curid=49495570
1,635,477
1,258,504
Physical activity is recommended for people with cerebral palsy, particularly in terms of cardiorespiratory endurance, muscle strengthening and reduction of sedentary behaviour. Participating in physical activity can supplement or replace some forms of therapy. It has been argued that people with cerebral palsy need to maintain a higher level of fitness than the general population to offset loss of functionality as they age. Access to exercise can often depend on the caregivers' perception of whether it will benefit the person with CP. There has been increasing interest in maintaining muscle strength through the lifespan of a person with CP. Aerobic capacity is not routinely assessed in people with cerebral palsy in a rehabilitation context, but Wingate tests have been advocated for use. Behavioural change methods have been used to promote physical activity among young people with cerebral palsy, but there is no significant evidence for these working. It is difficult to sustain behavioural change in terms of increasing physical activity of children with CP. Even though exercise is commonly recommended, there is only a small amount of evidence saying that aerobic exercise is good for gross motor function in children. Exercise can increase wellness in those with cerebral palsy. With regards to sports, the amount of exercise advised should be unique to the demands of the sport in question, the effect of the individual's condition on performance, and the potential to cause worsening of the condition. It is recommended, to encourage integrating moderate to vigorous exercise, including the use of a motor-assisted elliptical trainer. This is thought to improve fitness and the functioning.
https://en.wikipedia.org/wiki?curid=27399297
1,257,817
1,953,146
AGX Multiphysics (now renamed to AGX Dynamics) is a proprietary real-time physics engine developed by Algoryx Simulation AB that simulates rigid body dynamics, collision detection, dry frictional contacts, jointed systems, motors, fluids, deformable materials, hydraulics, hydrodynamics, cable systems and wires. AGX targets several domains, such as virtual reality real-time simulator applications for training and marketing; computer aided engineering and virtual prototyping; movie visual effects; and education. For education, components of AGX are used in the end-user software product Algodoo also developed and sold by Algoryx. Users of AGX simulate e.g. granular systems, construction equipment, forestry machines, mining processes and machines, biomechanics, industrial robots, ship and anchor handling processes and cranes. AGX is often integrated with 3D visualization frameworks such as OpenSceneGraph and OGRE and often also with actual hardware and control systems of the real-world version of the simulator. AGX is integrated in many 3D modeling and CAD systems, including Dynamics for SpaceClaim.
https://en.wikipedia.org/wiki?curid=31550858
1,952,025
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Other psychosocial studies involving astronauts and cosmonauts have been conducted. In one, an analysis of speech patterns as well as subjective attitudes and personal values were measured in both on-orbit space crews and people working in space analog environments. The researchers found that, over time, these isolated groups showed decreases in the scope and content of their communications and a filtering in what they said to outside personnel, which was termed psychological closing. Crew members interacted less with some mission control personnel than others, perceiving them as opponents. This tendency of some crew members to become more egocentric was called autonomization. They also found that crew members became more cohesive by spending time together (for example, joint birthday celebrations), and that the presence of subgroups and outliers (e.g., scapegoats) negatively affected group cohesion. In a study of 12 ISS cosmonauts, researchers reported that personal values generally remained stable, with those related to the fulfillment of professional activities and good social relationships being rated most highly.
https://en.wikipedia.org/wiki?curid=40399131
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After his undergraduate studies of chemistry at the Universities of Constance and Goettingen (Germany), Christopher Barner-Kowollik earns his PhD in physical chemistry (Dr. rer. nat.) from the University of Goettingen in 1999. Following postdoctoral research with Prof. Tom Davis at the University of New South Wales in Sydney, he held academic positions at the Centre for Advanced Macromolecular Design (CAMD), and was appointed Full Professor of Polymer Chemistry in 2006 at the same institution. In 2008 he moved back to Germany, where he became the Chair of Macromolecular Chemistry at the Karlsruhe Institute of Technology (KIT). There he was the founding director of the Collaborative Research Centre SFB 1176 'Molecular Structuring of Soft Matter' established by the German Research Council (DFG). He is a founding PI and thrust speaker in the DFG Excellence Cluster 3D Matter Made to Order. While he relocated in 2017 to the Queensland University of Technology (QUT), where he was awarded an Australian Laureate Fellowship and appointed Director of QUT's Soft Matter Materials Laboratory, Christopher Barner-Kowollik continues to be an associate group leader at the KIT's Institute of Nanotechnology and the Institute of Polymer Chemistry and Chemical Technology, after heading a full research group at the KIT until 2020. In December 2019, Christopher Barner-Kowollik was appointed Deputy Vice-Chancellor Research and Vice-President of the Queensland University of Technology (QUT).
https://en.wikipedia.org/wiki?curid=57789931
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More and more care is delivered not by individuals but by interprofessional healthcare teams that include nurses, social workers, and other care providers. In these settings, patients' health care decisions are shared with several professionals, whether concurrently or consecutively. The Interprofessional Shared Decision Making (IP-SDM) model is a three-level, two-axis framework that takes this complexity into account. Its three levels are contextual influences at the individual level, influences at the systemic or organizational level, and influences at the broader policy or social level. The axes are the SDM process (vertical) and the different people involved (horizontal). While interacting with one or more health professionals and family members, the patient moves through a structured process including explanation of the decision to be made; information exchange; eliciting values and preferences; discussing the feasibility of the options; the preferred choice versus the decision made; planning and implementing the decisions; and outcomes. Since this model was validated in 2011, it has been adopted in rehabilitation, dementia care, mental health, neonatal intensive care, hospital chaplaincy and educational research, among other fields.
https://en.wikipedia.org/wiki?curid=23453327
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Nintendo's product designer Lance Barr, who would continue with the company for decades, retooled the Famicom console with a sleek and sophisticated design language. The toy-like white-and-red color scheme of the Famicom was replaced with a clean and futuristic color scheme of grey, black, and red. The top and bottom portions are in different shades of grey, plus a stripe with black and ribbing along the top, and minor red accents. The shape is boxier: flat on top, and a bottom half that tapered down to a smaller footprint. The front of the main unit features a compartment for storing the wireless controllers out of sight. To avoid the stigma of video game consoles, Nintendo issued prerelease marketing of the AVS as a full home computer, with an included keyboard, cassette data recorder, and a BASIC interpreter software cartridge. The BASIC interpreter would later be sold together with a keyboard as the "Family BASIC" package, and the cassette deck for data storage would later be released as the Famicom Data Recorder. The AVS includes a variety of computer-style input devices: gamepads, a handheld joystick, a 3-octave musical keyboard, and the Zapper light gun. The AVS Zapper is hinged, allowing it to straighten out into a wand form, or bend into a gun form. The AVS uses a wireless infrared interface for all its peripherals, including keyboard, cassette deck, and controllers. Most of the peripherals for the Advanced Video System are on display at the Nintendo World Store.
https://en.wikipedia.org/wiki?curid=1571248
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Ethics pertain to the ‘’rightness’’ and ‘’wrongness’’ of human actions, motives, and conduct. Complicated ethical issues in areas such as justice, privacy, and autonomy, tend to follow both the field of genetics and the field of nursing. Ethical problems and dilemmas arise daily in healthcare settings for both the patient and health care provider. For example, all patients and individuals have the right to receive equal health care regardless of gender, religious beliefs, status, or race. A Code of Ethics for Nursing was created by the American Nurses Association, which provides rules, regulations, and guidelines to follow when making a decision that is ethical based. These regulations were mainly established to help provide equal healthcare, protect the rights, safety, and privacy of the patient, and to hold nurses accountable for their actions and choices. Genetics can create ethical issues in nursing for a variety of different situations. Many scenarios, questions, and debates have been encountered such as what individuals can receive genetic testing or information? Who owns or controls the information received from the genetic test and how can the owner use that information? However, the code of ethics does not address genetics or genomics specifically, so ethical foundations were also established to help guide genetics into health care. The foundations provide a set of guidelines to understand and manage an ethical issue if one should arise, and to assist in the translation of genetics into the healthcare environment.
https://en.wikipedia.org/wiki?curid=38429723
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The second group of these services is known as acute care in the digital health domain. These services include telemedicine which is defined as handling patients over some sort of streaming device and is targeted towards areas where the population is more widely scattered, medical devices that incorporate different aspects of software otherwise known as SaMD, and examples of these devices are pacemakers. The final example of acute care services is the 'interoperability' of 'Health IT, Cybersecurity, and Medical Devices', Health IT is how the electronic database stores, processes, and analyses personal health information and how this information can be utilized by medical personnel and organizations around the world of easier access of information, Cybersecurity which then plays into the storing of personal health information in how this information is secured and protected in the interest of personal safety of the individuals who's information is being stored, and Medical Devices that are able to communicate within each other to better care for a patient by transmitting what needs to be done on one machine to another. Sociologist Deborah Lupton states "However, members of some social groups are currently excluded from full participation in the digital health ecosystem. Mechanisms for facilitating further consultation between the various stakeholders involved in digital health, including patients and carers, need to be established. The rights and responsibilities of the different stakeholders involved in connected digital health also need to be better identified and highlighted. At the same time, personal data privacy and security need protection." Lupton concludes that despite the innovation of various elements in this digital health area, there are still multiple issues that need to be organized and dealt with for the continuation of the revolution of Digital Health.
https://en.wikipedia.org/wiki?curid=37451236
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The Howard government was resistant to taking action to prevent global warming that would harm Australia's economy, a policy continued from the prior Keating government. In 1996 in the lead up to the Kyoto treaty this slow going attitude caused conflict with the US and EU who at that time were proposing legally binding emissions targets as part of Kyoto. Australia was unwilling to accept stricter timeframes and emissions reductions targets, such as the 20% cut (from 1990 to 2005) proposed by smaller pacific island states, because of its carbon-intensive economy. Increasingly, in the lead up to the Kyoto conference, the Howard government became internationally isolated on its climate change policy. With Australia's opposition to binding targets "figur[ing] prominently in the prime minister's [recent] discussions in Washington and London" as highlighted in a Cabinet memo. In 1997 the Cabinet agreed to establish a climate change taskforce to strengthen its Kyoto bargaining position. In 1998 the Australian Government, under Prime Minister John Howard, established the Australian Greenhouse Office, which was then the world's first government agency dedicated to cutting greenhouse gas emissions, And, also in 1998, Australia signed but did not ratify the Kyoto protocols.
https://en.wikipedia.org/wiki?curid=20802345
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The Texas A&M Maritime Academy' (TMA) is one of only seven United States maritime academies that train U.S. Merchant Marine officers, and the only one located on the Gulf of Mexico. The program provides an opportunity for cadets to learn how to maintain and operate unlimited-tonnage ocean-going vessels. Students sail aboard the TMA training ship and commercial ships during three summer cruises to gain practical experience in navigation, seamanship, and engineering operations. In addition, the cadets receive classroom instruction and hands-on training during the regular school semester. Training facilities include the training ship, simulators, diesel and steam labs, various small boats, davits, and other hands-on resources. At the culmination of their study, license option or strategic sealift officer program cadets are tested to become licensed as unlimited-tonnage third mates or third engineers (officers) in the U.S. Merchant Marine. This is per Title 46 Code of the Code of Federal Regulation Part 11. The academy also commissions reserve and active duty naval officers.
https://en.wikipedia.org/wiki?curid=1373604
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In 1919 after the war, he returned to Ferranti and also remained in a consulting capacity to Lord Chetwynd and as a technical adviser to the British Mannesmann Tube company. Around 1922 Dr Ferranti became interested in the science of Radio and sound reproduction; it followed that Hall had to become interested too. His knowledge of operational calculus was well suited to dealing with the mathematical equations encountered in that field and allowed him to make the transition into Radio. At that time manufacturers paid royalties for each valve-holder that they fitted to a radio receiver, so they looked for ways to circumnavigate these royalties wherever they could. With this in mind, it also made sense to manufacture radio components for sale to other radio manufacturers and Hall soon became busy with this too. He was instrumental in designing and producing the AF family inter-valve audio frequency transformers for use in radio receivers. He also worked on valve (vacuum tube) development, producing several patents relating to Radio and component manufacture. In order to augment the sales of components to the amateur home constructor, Hall wrote a book that covered mathematical formula, radio-frequency amplification, loud speakers, power supplies and included many practical suggestions. At the annual Olympia Exhibition in 1929, Ferranti unveiled their first radio developed by Hall marketed as "The Standard Model 21" In 1931 Hall was responsible for employing Kenyon Taylor, who went on to become one of Ferranti's prolific inventors.
https://en.wikipedia.org/wiki?curid=45206191
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Ibercivis' predecessor, the University of Zaragoza-based volunteer computing project Zivis, began operation in 2007, and Ibercivis itself started operating in June 2008. The Zivis project was a local volunteer computing application funded by the "ayuntamiento" (city council) of the city of Zaragoza. The larger-scale Ibercivis infrastructure has been used for a variety of calculating applications, including nuclear fusion research, protein folding and materials simulations. In July 2009, the Ibercivis platform was extended to Portugal following an agreement signed by the governments of both countries during the Luso-Spanish Summit held in Zamora, Spain, in January 2009. Several Portuguese institutions subsequently affiliated themselves with Ibercivis, including the Ministry of Science, the Centre for Neuroscience and Cell Biology at the University of Coimbra, and the LIP experimental high-energy physics laboratory.
https://en.wikipedia.org/wiki?curid=18222953
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The global oceans cover 70% of the surface of the globe, consist of 95% of the living space, and are the core momentum of our planet’s physical, chemical, and biological cycles. As underlined in recent policy documents such as the Galway Statement and Belmont Challenge, in order to understand the changes predicted in the coming decades, EMSO aims to have a continuous presence in the oceans; and in order to understand both the slow moving and rapid catastrophes, EMSO seeks to have continuous real-time data from which to learn and to derive adaptation and early warning systems. Ocean observatories provide power and communications to allow a sustained interactive presence in the ocean. This challenge can only be addressed as part of an international cooperation between USA, Canada, Japan, Australia, Europe and other interested countries where EMSO takes a role for the European side.
https://en.wikipedia.org/wiki?curid=41693315
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The Spanish–American War was a short but decisive war marked by quick, overwhelming American victories at sea and on land against the Spanish Empire. The Navy was well-prepared and won laurels, even as politicians tried (and failed) to have it redeployed to defend East Coast cities against potential threats from the feeble Spanish Navy fleet. The Army performed well in combat in Cuba. However, it was too oriented to small posts in the West and not as well-prepared for an overseas conflict. It relied on volunteers and state militia units, which faced logistical, training and food problems in the staging areas in Florida. The United States freed Cuba (after an occupation by the U.S. Army). By the peace treaty Spain ceded to the United States its colonies of Puerto Rico, Guam, and the Philippines. The Navy set up coaling stations there and in Hawaii (which was forcibly overthrown in 1893, via a coup d'état against Queen Liliʻuokalani and annexed later in 1898). The U.S. Navy now had a major forward presence across the Pacific Ocean and (with the lease of Guantánamo Bay Naval Base in Cuba) a major base in the Caribbean guarding the approaches to the Gulf Coast and the Panama Canal.
https://en.wikipedia.org/wiki?curid=161323
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The DRAMBORA toolkit is intended to facilitate internal audit of digital preservation repositories by providing repository administrators with a means to assess their capabilities, identify their weaknesses, and recognise their strengths. The development of the toolkit follows a concentrated period of repository pilot audits undertaken by the DCC, conducted at a diverse range of organisations including national libraries, scientific data centres and cultural and heritage data archives. The construction of a toolkit of this kind is a dynamic process and this is the second stage in this process. The DRAMBORA toolkit represents the latest development in an ongoing international effort to conceive criteria, means and methodologies for audit and certification of digital repositories. The intention throughout its development was to build upon, extend and complement existing efforts. A key requirement has been to establish a toolkit that contributes towards a single process for repository assessment. The importance of international cooperation and collaboration, and the potential dangers associated with divergence were acknowledged very early on within the DCC and DPE's work in this area.
https://en.wikipedia.org/wiki?curid=10161835
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The "Betaproteobacteria" are a class comprising over 75 genera and 400 species of bacteria. Together, the "Betaproteobacteria" represent a broad variety of metabolic strategies and occupy diverse environments from obligate pathogens living within host organisms to oligotrophic groundwater ecosystems. Whilst most members of the "Betaproteobacteria" are heterotrophic, deriving both their carbon and electrons from organocarbon sources, some are photoheterotrophic, deriving energy from light and carbon from organocarbon sources. Other genera are autotrophic, deriving their carbon from bicarbonate or carbon dioxide and their electrons from reduced inorganic ions such as nitrite, ammonium, thiosulfate or sulfide — many of these chemolithoautotrophic. "Betaproteobacteria" are economically important, with roles in maintaining soil pH and in elementary cycling. Other economically important members of the "Betaproteobacteria" are able to use nitrate as their terminal electron acceptor and can be used industrially to remove nitrate from wastewater by denitrification. A number of "Betaproteobacteria" are diazotrophs, meaning that they can fix molecular nitrogen from the air as their nitrogen source for growth - this is important to the farming industry as it is a primary means of ammonium levels in soils rising without the presence of leguminous plants.
https://en.wikipedia.org/wiki?curid=5742360
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Unlike spectroscopic methods, X-ray crystallography always allows for unambiguous structure determination and provides precise bond angles and lengths totally unavailable through spectroscopy. It is often used in physical organic chemistry to provide an absolute molecular configuration and is an important tool in improving the synthesis of a pure enantiomeric substance. It is also the only way to identify the position and bonding of elements that lack an NMR active nucleus such as oxygen. Indeed, before x-ray structural determination methods were made available in the early 20th century all organic structures were entirely conjectural: tetrahedral carbon, for example, was only confirmed by the crystal structure of diamond, and the delocalized structure of benzene was confirmed by the crystal structure of hexamethylbenzene. While crystallography provides organic chemists with highly satisfying data, it is not an everyday technique in organic chemistry because a perfect single crystal of a target compound must be grown. Only complex molecules, for which NMR data cannot be unambiguously interpreted, require this technique. In the example below, the structure of the host–guest complex would have been quite difficult to solve without a single crystal structure: there are no protons on the fullerene, and with no covalent bonds between the two halves of the organic complex spectroscopy alone was unable to prove the hypothesized structure.
https://en.wikipedia.org/wiki?curid=11304514
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CCA1 is part of a negative autoregulatory feedback loop that is coordinated with the daily environmental changes. Repressed in the dark by other proteins, CCA1’s expression is activated when light is sensed by the phytochrome in the plant. After translation, the CCA1 protein needs to be phosphorylated by Casein Kinase 2 (CK2). This phosphorylation is necessary for the protein to form a homodimer and to bind to its target promoters. Hyperphosphorylation, due to the overexpression of CK2, will lead to altered circadian rhythms in the mutants where CCA1 showed shorter mRNA circadian oscillation than in wild-type plants. CK2 overexpression is significant in demonstrating CCA1 is part of the clock. The protein motif CCA1 uses to bind to its target DNA sequences is its Myb-like domain. CCA1 only has one Myb domain, whereas other plant and mammalian proteins could have multiple Myb domains. The presence of only one Myb domain in CCA1 shows its importance influence in the circadian clock. LUX is also an important Myb transcription factor that is necessary for CCA/LHY transcription. This can also help account for problems in the repressilator model described below. CCA1 is also unusual in that it has the ability to bind to asymmetric DNA sequences. CCA1 acts to suppress the expression of the DNA sequence it binds to. The stability of CCA1 protein is not affected by light or dark. It is regulated by its proteasome. Inhibiting proteasome function leads to a circadian rhythm with a longer period.
https://en.wikipedia.org/wiki?curid=46358103
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