doc_id
int32
18
2.25M
text
stringlengths
245
2.96k
source
stringlengths
38
44
__index_level_0__
int64
18
2.25M
242,614
As the 21st century progresses, the electric utility industry seeks to take advantage of novel approaches to meet growing energy demand. Utilities are under pressure to evolve their classic topologies to accommodate distributed generation. As generation becomes more common from rooftop solar and wind generators, the differences between distribution and transmission grids will continue to blur. In July 2017 the CEO of Mercedes-Benz said that the energy industry needs to work better with companies from other industries to form a "total ecosystem", to integrate central and distributed energy resources (DER) to give customers what they want. The electrical grid was originally constructed so that electricity would flow from power providers to consumers. However, with the introduction of DER, power needs to flow both ways on the electric grid, because customers may have power sources such as solar panels.
https://en.wikipedia.org/wiki?curid=20344155
242,487
205,590
A supplement to the factors that support life's emergence is the notion that life itself, once formed, becomes a habitability factor in its own right. An important Earth example was the production of molecular oxygen gas () by ancient cyanobacteria, and eventually photosynthesizing plants, leading to a radical change in the composition of Earth's atmosphere. This environmental change is called the Great Oxygenation Event. This oxygen proved fundamental to the respiration of later animal species. The Gaia hypothesis, a scientific model of the geo-biosphere pioneered by James Lovelock in 1975, argues that life as a whole fosters and maintains suitable conditions for itself by helping to create a planetary environment suitable for its continuity. Similarly, David Grinspoon has suggested a "living worlds hypothesis" in which our understanding of what constitutes habitability cannot be separated from life already extant on a planet. Planets that are geologically and meteorologically alive are much more likely to be biologically alive as well and "a planet and its life will co-evolve." This is the basis of Earth system science.
https://en.wikipedia.org/wiki?curid=2592906
205,484
1,375,316
It is possible to work in biological illustration without a specific degree, but a degree will significantly enhance an illustrator's employment opportunities. Job applications can be submitted to scientific researchers, publishers of scientific manuscripts, research institutions, museums, scientific foundations, commercial book publishers or university presses, individual authors, hospitals and medical training centers, local and state government offices, park services, environmental control offices, special government committees, printers and commercial publishing houses. Employment opportunities in the biological illustration profession are fairly limited, full-time jobs are not often available, and many experienced illustrators are self-employed, on short-term contracts, or work in science communication careers with few illustration duties. Many illustrators prefer the flexibility of their own working arrangements, but this is only possible when they are well established in the field and capable of locating work when needed. Many freelance illustrators supplement their salary with commercial illustration and graphic design projects, as is common in many art careers.
https://en.wikipedia.org/wiki?curid=42036843
1,374,557
1,920,449
ASTC is home to the Center for Advancement of Informal Science Education (CAISE). CAISE's charge is to strengthen and connect the informal science education (ISE) community by creating and disseminating resources, as well as catalyzing conversation and collaboration across the ISE field—including film and broadcast media, science centers and museums, zoos and aquariums, botanical gardens and nature centers, digital media and gaming, science journalism, and youth, community, and after-school programs. Founded in 2007 with support from the National Science Foundation (NSF) Advancing Informal STEM Learning (AISL) program, CAISE is a partnership among ASTC and Co-Principal Investigators at Oregon State University (OSU), the University of Pittsburgh Center for Learning in Out-of-School Environments (UPCLOSE), The Great Lakes Science Center and KQED San Francisco. CAISE manages the InformalScience.org website, which is a repository of project descriptions, evaluation reports and tools, and research papers and products that are collected and curated to provide informal STEM Learning practitioners with knowledge that can be used when developing new work and seeking potential collaborators.
https://en.wikipedia.org/wiki?curid=7740810
1,919,346
499,124
Some programs of research in sociology employ experimental methods to study social interaction processes. Joseph Berger and his colleagues initiated such a program in which the central idea is the use of the theoretical concept "expectation state" to construct theoretical models to explain interpersonal processes, e.g., those linking external status in society to differential influence in local group decision-making. Much of this theoretical work is linked to mathematical model building, especially after the late 1970s adoption of a graph theoretic representation of social information processing, as Berger (2000) describes in looking back upon the development of his program of research. In 1962 he and his collaborators explained model building by reference to the goal of the model builder, which could be explication of a concept in a theory, representation of a single recurrent social process, or a broad theory based on a theoretical construct, such as, respectively, the concept of balance in psychological and social structures, the process of conformity in an experimental situation, and stimulus sampling theory.
https://en.wikipedia.org/wiki?curid=4771336
498,867
1,694,335
The IBM FlashSystem architecture was originally developed by Texas Memory Systems (TMS) as their RamSan product line. TMS was a small private company founded in 1978 and based in Houston, Texas that supplied solid-state drive products to the market longer than any other company. The TMS RamSan line of enterprise solid state storage products was first launched in the early 2000s with the RamSan-520, and over seven RamSan technology generations were released through 2012, when TMS was acquired by IBM. As RamSan technology evolved, TMS adapted the systems to different storage media (DRAM, single-level cell flash memory, and multi-level cell flash memory) and external storage area network interfaces (Fibre Channel and InfiniBand), but the core system design principles remained relatively constant: custom hardware with a shared internal network to maximize speed, particularly latency. The last RamSan products available were the RamSan-710, RamSan-810, RamSan-720, and RamSan-820 systems, which were replaced directly with corresponding IBM FlashSystem products in 2013.
https://en.wikipedia.org/wiki?curid=37187554
1,693,384
1,612,665
The generation process starts with a set of atoms from the molecular formula. In structure assembly, atoms are combinatorically connected to consider all possible extensions. If substructures are obtained from the experimental data, the generation starts with these substructures.These substructures provide known bonds in the molecule. One of the earliest attempts was made by Hidetsugu Abe in 1975 using a pattern recognition-based structure generator. The algorithm had two steps: first, the prediction of the substructure from low-resolution spectral data; second, the assembly of these substructures based on a set of construction rules. Hidetsugu Abe and the other contributors published the first paper on CHEMICS, which is a CASE tool comprising several structure generation methods. The program relies on a predefined non-overlapping fragment library. CHEMICS generates different types of component sets ranked from primary to tertiary based on component complexity. The primary set contains atoms, i.e., C, N, O and S, with their hybridization. The secondary and tertiary component sets are built layer-by-layer starting with these primary components. These component sets are represented as vectors and are used as building blocks in the process.
https://en.wikipedia.org/wiki?curid=66452088
1,611,760
1,250,702
Health and Welfare Canada reviewed "How to Practice Prospective Medicine" and created a mainframe version of the book. The Centers for Disease Control became aware of this product and adapted it to the newly available personal computer. When Prudential Life Insurance also took an interest and asked to fund an update of the program, the CDC, which could not accept private project funding at the time, transferred ownership to the Carter Center at Emory University where it was updated from 1986 to 1987. The transfer and subsequent program were managed by Dr. Ed Hutchins, who had worked on the HRA in positions at the University of Pennsylvania and Charlotte-Mecklenburg Hospital. At Charlotte Mecklenburg, he secured a contract with the World Health Organization to create a mainframe product that could be used on an international basis.
https://en.wikipedia.org/wiki?curid=15588392
1,250,026
695,885
The wild-type of the species has 8 or 9 black vertical bars on a blue-grey body, along with a dark blotch on the operculum. Juvenile convict cichlids are monomorphic until they reach sexual maturity. The male is mostly gray with light black stripes along the body. Males are larger than females, and they have more pointed ventral, dorsal and anal fins which often extend into filaments. In addition, older males frequently develop vestigial fatty lumps on their foreheads. Unusually for fish, the female is more highly coloured. She has more intense black bands across the body, and pink to orange colouration in the ventral region and on the dorsal fin. The maximum standard length has been reported to be 10 centimeters, with total length near . The body weight of the fish is about . Selective breeding has resulted in a leucistic strain, which lacks the dark barring of the wild type. These are known commonly as white convicts, pink convicts, gold convicts, and "A. nigrofasciata" "Kongo". The leucistic colouration is caused by a mutation in an autosomal gene and is recessively inherited.
https://en.wikipedia.org/wiki?curid=2676776
695,521
1,159,029
The 3D structure of this channel at closed state was elucidated after the crystallography study by Bass et al. which showed that at resolution of 3.9 Å this 31kDa protein is an homoheptamer forming a channel with 80 Å of diameter and 120 Å in length, each subunit contains three transmembrane domains (TM1, TM2, and TM3) with the N-terminal facing the periplasm and the C-terminal embedded in the cytoplasm. The TM3 is highly conserved in MscS family and it is thought to play an important role in MS prokaryotic gating. MscS is a small protein composed of 286 amino acid residues activated by both tension in the lipid bilayer and voltage; in 2002 Vasquez et al. detailed this process and showed that during the change from closed state to open state the TM1 tilt and rotate making TM2 being exposed to the membrane and the TM3 helices expand, tilt, and rotate. During the rearrangement the confined part of the pore was measured as 11 Å, and water molecules were more accessible to the TM3. The two transmembrane domains are in continuous contact with the lipid bilayer and are thought to be the sensor for the tension in the lipid bilayer as well as sensor for voltage because of the three arginine residues present in those domains.
https://en.wikipedia.org/wiki?curid=22585641
1,158,415
189,971
By the seventh generation, Sony, Microsoft, and Nintendo had all developed consoles designed to interface with the Internet, adding networking support for either wired and wireless connections, online services to support multiplayer games, digital storefronts for digital purchases of games, and both internal storage and support for external storage on the console for these games. With the start and transition to the HD-era, these consoles also added support for digital television resolutions through HDMI interfaces, but as the generation occurred in the midst of the High-definition optical disc format war between Blu-ray and HD-DVD, a standard for high-definition playback was yet to be fixed. A further innovation came by the use of motion controllers, either built into the console or offered as an add-on afterwards. Consoles in this generation started using custom CPUs based on the PowerPC instruction set, and were increasingly sharing similarities with the personal computer in game development, although with challenges due to the more complex nature of porting between the differences in architectures.
https://en.wikipedia.org/wiki?curid=982571
189,874
198,859
AMD began releasing details of their next generation of GCN Architecture, termed the 'Next-Generation Compute Unit', in January 2017. The new design was expected to increase instructions per clock, higher clock speeds, support for HBM2, a larger memory address space. The discrete graphics chipsets also include "HBCC (High Bandwidth Cache Controller)", but not when integrated into APUs. Additionally, the new chips were expected to include improvements in the Rasterisation and Render output units. The stream processors are heavily modified from the previous generations to support packed math Rapid Pack Math technology for 8-bit, 16-bit, and 32-bit numbers. With this there is a significant performance advantage when lower precision is acceptable (for example: processing two half-precision numbers at the same rate as a single single precision number).
https://en.wikipedia.org/wiki?curid=33421692
198,757
1,499,619
After the 1968 failure of Prague spring, Kroupa's family fled from Czechoslovakia losing all possessions; as a consequence Kroupa grew up in Germany and South Africa. He acquired in 1983 his Abitur final exams in Göttingen and afterwards studied physics at The University of Western Australia in Perth. In 1988 he won the Isaac Newton scholarship at the University of Cambridge and in 1992 the senior Rouse Ball research scholarship at Trinity College, Cambridge and attained a doctorate in England in 1992 with a dissertation on the distribution of low mass stars in the Milky Way. Afterwards Kroupa worked until 2000 in astronomical research groups at Heidelberg University and at the Max Planck Institute for Astronomy, before he went to the University of Kiel and earned his Habilitation there. He was awarded a Heisenberg Fellowship in 2002. In April 2004 he was appointed to the observatory of the University of Bonn, which is today a department of the Argelander Institute for Astronomy. He was honoured in 2007 by a Swinburne University Visiting Professorship in Melbourne and by a Leverhulme Trust Visiting Professorship at the University of Sheffield.
https://en.wikipedia.org/wiki?curid=33413785
1,498,774
960,609
In the United States, Water Quality Standards are defined by state agencies for various water bodies, guided by the desired uses for the water body (e.g., fish habitat, drinking water supply, recreational use). The Clean Water Act (CWA) requires each governing jurisdiction (states, territories, and covered tribal entities) to submit a set of biennial reports on the quality of water in their area. These reports are known as the 303(d) and 305(b) reports, named for their respective CWA provisions, and are submitted to, and approved by, EPA. These reports are completed by the governing jurisdiction, typically a . EPA recommends that each state submit a single "Integrated Report" comprising its list of impaired waters and the status of all water bodies in the state. The "National Water Quality Inventory Report to Congress" is a general report on water quality, providing overall information about the number of miles of streams and rivers and their aggregate condition. The CWA requires states to adopt standards for each of the possible designated uses that they assign to their waters. Should evidence suggest or document that a stream, river or lake has failed to meet the water quality criteria for one or more of its designated uses, it is placed on a list of impaired waters. Once a state has placed a water body on this list, it must develop a management plan establishing Total Maximum Daily Loads (TMDLs) for the pollutant(s) impairing the use of the water. These TMDLs establish the reductions needed to fully support the designated uses.
https://en.wikipedia.org/wiki?curid=306773
960,100
444,022
He was of ethnic German as well as had a great deal of ethnic Scottish, English, Welsh, Huguenot French and Scotch Irish ancestry, Townes was born in Greenville, South Carolina, the son of Henry Keith Townes (1876–1958), an attorney, and Ellen Sumter Townes (née Hard; 1881–1980). His brother, Henry Keith Townes, Jr., (01/20/1913-05/2/1990), was a renowned entomologist who was a world authority on Ichneumon wasps. He earned his B.S. in Physics and B.A. in Modern Languages at Furman University, where he graduated in 1935. Townes completed work for the Master of Arts degree in physics at Duke University during 1937, and then began graduate school at the California Institute of Technology, from which he received a Ph.D. degree in 1939. During World War II, he worked on radar bombing systems at Bell Labs.
https://en.wikipedia.org/wiki?curid=396568
443,807
762,309
Seaborg's theoretical development of the actinide concept resulted in a redrawing of the periodic table into its current configuration with the actinide series appearing below the lanthanide series. Seaborg developed the chemical elements americium and curium while in Chicago. He managed to secure patents for both elements. His patent on curium never proved commercially viable because of the element's short half-life, but americium is commonly used in household smoke detectors and thus provided a good source of royalty income to Seaborg in later years. Prior to the test of the first nuclear weapon, Seaborg joined with several other leading scientists in a written statement known as the Franck Report (secret at the time but since published) unsuccessfully calling on President Truman to conduct a public demonstration of the atomic bomb witnessed by the Japanese.
https://en.wikipedia.org/wiki?curid=13120
761,901
1,242,256
In July 1992 LLNL responded to these suggestions with the Nova Upgrade, which would reuse the majority of the existing Nova facility, along with the adjacent Shiva facility. The resulting system would be much lower power than the LMF concept, with a driver of about 1 to 2 MJ. The new design included a number of features that advanced the state of the art in the driver section, including the multi-pass design in the main amplifiers, and 18 beamlines (up from 10) that were split into 288 "beamlets" as they entered the target area in order to improve the uniformity of illumination. The plans called for the installation of two main banks of laser beam lines, one in the existing Nova beam line room, and the other in the older Shiva building next door, extending through its laser bay and target area into an upgraded Nova target area. The lasers would deliver about 500 TW in a 4 ns pulse. The upgrades were expected to allow the new Nova to produce fusion yields between 2 and 20 MJ The initial estimates from 1992 estimated construction costs around $400 million, with construction taking place from 1995 to 1999.
https://en.wikipedia.org/wiki?curid=2700382
1,241,584
1,909,894
Goebel played in the game with an injured knee and wore a fitted steel hinge – an early version of a knee brace. "Before each game, Goebel liberally oiled the hinge to get free action", but his playing time was limited because "the constant action would dry the oil and then the steel would become so hot that Goebel could not continue playing." Despite the limitations of the knee brace, Goebel blocked a punt in the first quarter and then kicked a long field goal from the 30-yard line for the game's first points. He also penetrated into the Ohio State backfield in the second quarter to recover a fumble. As the game wore on, the Buckeyes "seemed to realize (Goebel's) importance in the Michigan lineup because he was forced to take plenty of punishment." Sports columnist Billy Evans wrote: "No end in recent years has played a greater game (than) that which Goebel put up against Ohio State. For three periods Goebel was the mainspring of the Michigan eleven. He seemed to be in every play. It was always Goebel who was gumming things up for State. No man could go through an entire game at the speed with which Goebel played in the first three quarters. It was beyond the power of any human being. With a few minutes to play in the third period the big fellow practically collapsed. Even when three or four of his teammates were carrying him off the field the old spirit was still there. He tried to induce his teammates that he was able to play, and tried to break away from their grasp, but the punch was gone and he was forced to give way as the big crowd cheered him to the echo. If any one man made possible the defeat of State by Michigan, it was Captain Paul Goebel."
https://en.wikipedia.org/wiki?curid=25642546
1,908,796
643,095
When Sullivan visited her family for Christmas in 1976, her brother Grant, an aerospace engineer and corporate jet pilot, told her that the National Aeronautics and Space Administration (NASA) had issued a call for applications for a new group of astronauts. NASA had made it known that it was interested in recruiting women, and Grant encouraged her to apply. He had applied for both pilot and mission specialist positions. After she returned to Nova Scotia she saw a NASA ad in a science journal, and decided to apply. She reasoned that the Space Shuttle was a kind of research vessel, but her dream was still to descend to the ocean floor in a submersible. That prospect came closer when she received an offer from William B. F. Ryan from the Lamont–Doherty Earth Observatory at Columbia University to join his team exploring the ocean in the submersible . Ryan had been an unsuccessful finalist for NASA Astronaut Group 6 in 1967, and he counseled her to wait for NASA to call. They both felt that the odds on being accepted were long, but Sullivan did not join Ryan's team while she waited to hear about her selection.
https://en.wikipedia.org/wiki?curid=498730
642,756
1,073,425
Wood started a company now called Avita Medical to commercialise the procedure. Her business came about after a schoolteacher arrived at Royal Perth Hospital in 1992 with petrol burns to 90% of his body. Wood turned to the emerging US-invented technology of cultured skin to save his life, working nights in a laboratory along with scientist Marie Stoner. The two women began to explore tissue engineering. They moved from growing skin sheets to spraying skin cells; earning a worldwide reputation as pioneers in their field. The company started operating in 1993 and now cultures small biopsies into bigger volumes of skin cell suspensions in as few as five days. This service is used by surgeons in Sydney, Auckland and Birmingham. Cells can be delivered via aircraft and ready for use the next day in many cases. Royalties from licensing will be ploughed back into a research fund, named the McComb Foundation.
https://en.wikipedia.org/wiki?curid=34892522
1,072,871
112,431
It is hypothesized that the initial or repetitive injury in IPF occurs to the lung cells, called alveolar epithelial cells (AECs, pneumocytes), which line the majority of the alveolar surface. When type I AECs are damaged or lost, it is thought that type II AECs undergo proliferation to cover the exposed basement membranes. In normal repair, the hyperplastic type II AECs die and the remaining cells spread and undergo a differentiation process to become type I AECs. Under pathologic conditions and in the presence of transforming growth factor beta (TGF-β), fibroblasts accumulate in these areas of damage and differentiate into myofibroblasts that secrete collagen and other proteins. In the current classification of the pathogenesis of IPF, it is believed that it occurs by way of the formation of a UIP (usual interstitial pneumonia) lesion, which then undergoes the aforementioned pathological condition characteristic of IPF. Other proposed repeated injury mechanisms indicate that IPF may result not just from a UIP lesion, but also from NSIP and DAD (nonspecific interstitial pneumonia and diffuse alveolar damage) lesions, or a combination of several.
https://en.wikipedia.org/wiki?curid=8768565
112,386
730,804
Distributed systems like Google Map Reduce, Microsoft Dryad, Apache Hadoop (an open-source project) and Google Pregel provide such platforms for businesses and users. However, even with these systems, big data analytics can take several hours, days or weeks to run, simply due to the data volumes involved. For example, a ratings prediction algorithm for the Netflix Prize challenge took nearly 20 hours to execute on 50 cores, and a large-scale image processing task to estimate geographic information took 3 days to complete using 400 cores. "The Large Synoptic Survey Telescope is expected to generate terabytes of data every night and eventually store more than 50 petabytes, while in the bioinformatics sector, the largest genome 12 sequencing houses in the world now store petabytes of data apiece."
https://en.wikipedia.org/wiki?curid=44783487
730,419
2,167,352
But investments require fund, and to cover such an expensive enterprise Goodale approached his former student Mary Lee Ware and her mother with his idea. Being independently wealthy and (already) liberal benefactors of Harvard's botanical department, Mary convinced her mother to agree to underwrite the consignment of the uncannily lifelike models they both were enchanted by. The contract signed dictated that the Blaschkas need only work half-time on the models (beginning in 1887) but, in 1890, they and Goodale - signing on behalf of the Wares - signed an updated version that allowed Leopold and Rudolf to work on them full-time; some sources detail the agreement as a shift from a 3-year contract to a 10-year one, agreed to once Goodale convinced Mary and her mother of the wisdom in doing so. Either way, the Wares liberally funded the entire enterprise. To this day the now world famous Glass Flowers are still on display at the Harvard Museum of Natural History — the exhibit itself dedicated to Dr. Charles Eliot Ware (the deceased father and husband of Mary L. and Elizabeth C. Ware respectively), the official name being "The Ware Collection of Blaschka Glass Models of Plants". Moreover, unlike the glass marine invertebrates — which were "a profitable global mail-order business", the Glass Flowers were commissioned solely for and are unique to Harvard.
https://en.wikipedia.org/wiki?curid=5154908
2,166,115
1,811,474
Siderophores are typically bound to siderocalin with subnanomolar affinities, and interact with siderocalin specifically. The Kd value of the siderocalin/siderophore interaction, measured by fluorescence quenching (Kd= 0.4 nM), indicates that siderocalin can capture siderophores with high affinity. This Kd value is similar to that of the FepA bacterial receptor (Kd= 0.3 nM). Siderophore/siderocalin binding is directed by electrostatic interactions. Specifically, the mechanism involves hybrid electrostatic and cation-pi interactions in the positively charged protein calyx. The siderophore is positioned in the centre of the siderocalin calyx, and is associated with multiple direct polar interactions. Structural analysis of the siderocalin/siderophore interaction has shown that the siderophore is accompanied by a poor and diffuse quality of electron density, with the majority of the ligand exposed to the solvent when the siderophore is fit in the calyx. Siderocalin typically does not bind hydroxamate-based siderophores because these substrates do not have the necessary aromatic electronic structure for cation-pi interactions. In order to acquire iron in the presence of siderocalin, pathogenic bacteria utilize several siderophores that do not bind to siderocalin, or structurally modify siderophores to inhibit siderocalin binding. Siderocalin can bind soluble siderophores of mycobacteria, including carboxymycobactins.
https://en.wikipedia.org/wiki?curid=45079586
1,810,441
1,320,106
Raine spent four years in two high-security prisons in England working as a prison psychologist. He was appointed lecturer in Behavioural Sciences in the Department of Psychiatry at Nottingham University in 1984 and in 1986 became director of the Mauritius Child Health Project, a continuing longitudinal study of child mental health following a group of 1795 people form Mauritius from the age of three onward. Raine moved to the United States in 1987 to become assistant professor in psychology at the University of Southern California (USC). His motives in moving from Britain to the United States were twofold: first, he thought that American scientists were more open-minded regarding the potential role of genetics in crime than their British counterparts, and second, there were more murderers in the United States for him to study. He was promoted to tenured associate professor there in 1990. In 1999, he was given the endowed chair of Robert G. Wright Professor of Psychology at USC. In 2007, he made the move to serve as Richard Perry University Professor of Criminology & Psychiatry at the University of Pennsylvania. He also serves as the University's fourth Penn Integrates Knowledge professor.
https://en.wikipedia.org/wiki?curid=11267046
1,319,380
777,496
On 31 December 1986, the first prototype took off on its maiden flight. The test pilot, Menachem Shmul, head of IAI's Air Operations section, took off at 13:21 and stayed in the air for 26 minutes, during which he checked the engine and controls. The handling was described as "excellent", with a high degree of stability in crosswind landings. About three months later, a second "Lavi" prototype took to the air; it featured improvements and additional features over the first, with a belly-mounted fuel tank, a special midair refuelling probe and several new avionic systems. Both B-01 and B-02 were tandem two-seaters, with the rear cockpit occupied by test equipment. By August 1987, the month in which the Lavi was canceled, a total of 82 sorties had reportedly been flown between the two completed prototypes, during which a significant proportion of the flight envelope had been explored.
https://en.wikipedia.org/wiki?curid=1254910
777,079
552,987
Through calculations based on the size of their limb bones and a humerus (no complete skeleton has yet been recovered), the Dmanisi individuals were approximately 145–166 cm (4.8–5.4 ft) tall and weighed about 40–50 kg (88–110 lbs). They were smaller than "H. ergaster" in Africa, possibly either due to being more primitive ("H. habilis" was also smaller than "H. ergaster") or due to having adapted to a different environment. Limb proportions (measured through the length of the femur relative to the tibia) in the Dmanisi fossils are comparable to those of modern humans, but are also comparable to some of the earliest "Homo" and fossils referred to "Australopithecus garhi", dated to 2.5 million years old. In terms of the absolute length of the legs, the Dmanisi hominins were more similar to later "Homo" (including modern humans) than to australopithecines,' though the length of legs and the morphology of the metatarsals in the Dmanisi hominins was not as derived as later "H. ergaster"/"H. erectus" (such as Turkana Boy). This might indicate that the evolution of improved walking and running performance was not a sudden change, but a continual process throughout the Early and Middle Pleistocene.'
https://en.wikipedia.org/wiki?curid=60072585
552,698
848,784
In the spring of 1993, the Base Realignment and Closure (BRAC) Commission rejected suggestions that the institute be moved or closed, and recommended that its mission be continued at the present location. In summer of 2005, the commission reopened the issue, to include the closure of the Naval Postgraduate School. Supporters of the closure believed that due to the rising property values and cost of living in the Monterey Bay area, taxpayers would save money by moving both schools to a less expensive location in Ohio. Opponents argued that it would be difficult (if not impossible) to replace the experienced native-speaking faculty at DLI, as the cultural centers of San Francisco and California's Central Coast offer a more diverse pool from which to recruit local instructors, and that the military intelligence community would suffer as a result. The BRAC commission met in Monterey on 8 August 2005, to hear arguments from both sides. On 25 August 2005, the commission's final vote was unanimous to keep DLI at its current location in Monterey.
https://en.wikipedia.org/wiki?curid=936948
848,334
1,830,999
He developed, with Prof J Troe, easily used approximate solutions for the pressure dependence of the rate coefficient. He provided the first solutions for cases where angular momentum conservation needs to be incorporated. His methods are used by experimentalists to fit data and extrapolate to different pressure regimes, supplanting previous tools which were of dubious validity and accuracy. His coworkers and he obtained data on the collisional energy transfer process and used them to prove the conjecture that each collision involves only a small exchange of energy. He then developed the first rigorous means to calculate these quantities from basic theory, and the first physical model for the process. His work is widely used, both for basic understanding of the transition states and by atmospheric and combustion modellers. Predicting climate change and effects on the ozone layer rely critically on this modelling.
https://en.wikipedia.org/wiki?curid=4384325
1,829,953
1,269,336
Visualization played an important role at the beginning of topological knot theory, when polyhedral decompositions were used to compute the homology of covering spaces of knots. Extending to 3 dimensions the physically impossible Riemann surfaces used to classify all closed orientable 2-manifolds, Heegaard's 1898 thesis "looked at" similar structures for functions of two complex variables, taking an imaginary 4-dimensional surface in Euclidian 6-space (corresponding to the function f=x^2-y^3) and projecting it stereographically (with multiplicities) onto the 3-sphere. In the 1920s Alexander and Briggs used this technique to compute the homology of cyclic branched covers of knots with 8 or fewer crossings, successfully distinguishing them all from each other (and the unknot). By 1932 Reidemeister extended this to 9 crossings, relying on linking numbers between branch curves of non-cyclic knot covers. The fact that these imaginary objects have no "real" existence does not stand in the way of their usefulness for proving knots distinct. It was the key to Perko's 1973 discovery of the duplicate knot type in Little's 1899 table of 10-crossing knots.
https://en.wikipedia.org/wiki?curid=25948250
1,268,645
842,774
Strains of "T. rubrum" form two distinct biogeographical subpopulations. One is largely restricted to parts of Africa and southern Asia, while the other consists of a population that has spread around the world. Isolates of the Afro-Asiatic subpopulation most commonly manifest clinically as tinea corporis and tinea capitis. In contrast, the globally-distributed subpopulation manifests predominantly in tinea pedis and tinea unguium. Different members of the "T. rubrum" complex are endemic to different regions; isolates previously referred to "T. megninii" originate from Portugal, while "T. soudanense" and "T. gourvilii" are found in Sub-Saharan Africa. All species included in the "T. rubrum" complex are "–" mating type with the exception of "T. megninii" which represents the "+" mating type and is auxotrophic for -histidine. The mating type identity of "T. soudanense" remains unknown. "Trichophyton raubitschekii," which is common from northwestern India and southeast Asia as well as parts of West Africa, is characterized by strongly granular colonies and is the only variant in the complex that reliably produces urease. In addition to the regioselectivity of these variants of the genus "Trichophyton", combinations of varying species of the genus can have multiplicative effects that are invisible to the host immune system, resulting in potentially chronic infection.
https://en.wikipedia.org/wiki?curid=9784397
842,324
771,134
In 1995, the African Programme for Onchocerciasis Control (APOC) began covering another 19 countries, mainly relying upon the use of the drug ivermectin. Its goal was to set up community-directed treatment with ivermectin for those at risk of infection. In these ways, transmission has declined. APOC closed in 2015 and aspects of its work taken over by the WHO Expanded Special Programme for the Elimination of Neglected Tropical Diseases (ESPEN). As in the Americas, the objective of ESPEN working with Government Health Ministries and partner NGDOs, is the elimination of transmission of onchocerciasis. This requires consistent annual treatment of 80% of the population in endemic areas for at least 10–12 years – the life span of the adult worm. No African country has so far verified elimination of onchocerciasis, but treatment has stopped in some areas (e.g. Nigeria), following epidemiological and entomological assessments that indicated that no ongoing transmission could be detected. In 2015, WHO facilitated the launch of an elimination program in Yemen which was subsequently put on hold due to conflict.
https://en.wikipedia.org/wiki?curid=276846
770,720
50,207
Approximately 10 percent of IBS cases are triggered by an acute gastroenteritis infection. The CdtB toxin is produced by bacteria causing gastroenteritis and the host may develop an autoimmunity when host antibodies to CdtB cross-react with vinculin. Genetic defects relating to the innate immune system and epithelial barrier as well as high stress and anxiety levels appear to increase the risk of developing post-infectious IBS. Post-infectious IBS usually manifests itself as the diarrhea-predominant subtype. Evidence has demonstrated that the release of high levels of proinflammatory cytokines during acute enteric infection causes increased gut permeability leading to translocation of the commensal bacteria across the epithelial barrier; this in turn can result in significant damage to local tissues, which can develop into chronic gut abnormalities in sensitive individuals. However, increased gut permeability is strongly associated with IBS regardless of whether IBS was initiated by an infection or not. A link between small intestinal bacterial overgrowth and tropical sprue has been proposed to be involved as a cause of post-infectious IBS.
https://en.wikipedia.org/wiki?curid=210596
50,187
315,518
Approximately 80% of rhenium is extracted from porphyry molybdenum deposits. Some ores contain 0.001% to 0.2% rhenium. Roasting the ore volatilizes rhenium oxides. Rhenium(VII) oxide and perrhenic acid readily dissolve in water; they are leached from flue dusts and gasses and extracted by precipitating with potassium or ammonium chloride as the perrhenate salts, and purified by recrystallization. Total world production is between 40 and 50 tons/year; the main producers are in Chile, the United States, Peru, and Poland. Recycling of used Pt-Re catalyst and special alloys allow the recovery of another 10 tons per year. Prices for the metal rose rapidly in early 2008, from $1000–$2000 per kg in 2003–2006 to over $10,000 in February 2008. The metal form is prepared by reducing ammonium perrhenate with hydrogen at high temperatures:
https://en.wikipedia.org/wiki?curid=25603
315,349
239,309
The Turk began its European tour in 1783, beginning with an appearance in France in April. A stop at Versailles beginning on April 17, preceded an exhibition in Paris, where the Turk lost a match to Charles Godefroy de La Tour d'Auvergne, the . Upon arrival in Paris in May 1783, it was displayed to the public and played a variety of opponents, including a lawyer named Mr. Bernard who was a second rank in chess ability. Following the sessions at Versailles, demands increased for a match with François-André Danican Philidor, who was considered the best chess player of his time. Moving to the Café de la Régence, the machine played many of the most skilled players, often losing (e.g. against Bernard and Verdoni), until securing a match with Philidor at the Académie des Sciences. While Philidor won his match with the Turk, Philidor's son noted that his father called it "his most fatiguing game of chess ever!" The Turk's final game in Paris was against Benjamin Franklin, who was serving as ambassador to France from the United States. Franklin reportedly enjoyed the game with the Turk and was interested in the machine for the rest of his life, keeping a copy of Philip Thicknesse's book "The Speaking Figure and the Automaton Chess Player, Exposed and Detected" in his personal library.
https://en.wikipedia.org/wiki?curid=418820
239,189
338,128
In a QDSC, a mesoporous layer of titanium dioxide nanoparticles forms the backbone of the cell, much like in a DSSC. This layer can then be made photoactive by coating with semiconductor quantum dots using chemical bath deposition, electrophoretic deposition or successive ionic layer adsorption and reaction. The electrical circuit is then completed through the use of a liquid or solid redox couple. The efficiency of QDSCs has increased to over 5% shown for both liquid-junction and solid state cells, with a reported peak efficiency of 11.91%. In an effort to decrease production costs, the Prashant Kamat research group demonstrated a solar paint made with and CdSe that can be applied using a one-step method to any conductive surface with efficiencies over 1%. However, the absorption of quantum dots (QDs) in QDSCs is weak at room temperature. The plasmonic nanoparticles can be utilized to address the weak absorption of QDs (e.g., nanostars). Adding an external infrared pumping source to excite intraband and interband transition of QDs is another solution.
https://en.wikipedia.org/wiki?curid=2352910
337,948
583,822
Harrison Brown and associates stated that humanity will process lower and lower grade "ore". Iron will come from low-grade iron-bearing material such as raw rock from anywhere in an iron formation, not much different from the input used to make taconite pellets in North America and elsewhere today. As coking coal reserves decline, pig iron and steel production will use non-coke-using processes (i.e. electric steel). The aluminum industry could shift from using bauxite to using anorthosite and clay. Magnesium metal and magnesia consumption (i.e. in refractories), currently obtained from seawater, will increase. Sulfur will be obtained from pyrites, then gypsum or anhydrite. Metals such as copper, zinc, nickel, and lead will be obtained from manganese nodules or the Phosphoria formation (sic!). These changes could occur irregularly in different parts of the world. While Europe and North America might use anorthosite or clay as raw material for aluminum, other parts of the world might use bauxite, and while North America might use taconite, Brazil might use iron ore. New materials will appear (note: they have), the result of technological advances, some acting as substitutes and some with new properties. Recycling will become more common and more efficient (note: it has!). Ultimately, minerals and metals will be obtained by processing "average" rock. Rock, 100 tonnes of "average" igneous rock, will yield eight tonnes of aluminum, five tonnes of iron, and 0.6 tonnes of titanium.
https://en.wikipedia.org/wiki?curid=19080286
583,523
846,959
The competing AMD Athlon 64 X2, although running at lower clock rates and lacking Hyper-threading, had some significant advantages over the Pentium D, such as an integrated memory controller, a high-speed HyperTransport bus, a shorter pipeline (12 stages compared to the Pentium D's 31), and better floating point performance, more than offsetting the difference in raw clock speed. Also, while the Athlon 64 X2 inherited mature multi-core control logic from the multi-core Opteron, the Pentium D was seemingly rushed to production and essentially consisted of two CPUs in the same package. Indeed, shortly after the launch of the mainstream Pentium D branded processors (26 May 2005) and the Athlon 64 X2 (31 May 2005), a consensus arose that AMD's implementation of multi-core was superior to that of the Pentium D. As a result of this and other factors, AMD surpassed Intel in desktop PC sales at US retail stores for a period of time, although Intel retained overall market leadership because of its exclusive relationships with direct sellers such as Dell.
https://en.wikipedia.org/wiki?curid=1560876
846,509
1,479,873
The system could be operated at four frequencies between 2,700 and 2,800 MHz (10–11 cm wavelength), sending out 300 kW pulses of 0.8 microseconds in duration with a pulse repetition frequency (PRF) of 1,707 pulses per second. It could detect bomber-sized targets at about 40 miles range, and was generally able to automatically track them at about 18 miles. Accuracy within this range was 25 yards in range, and 0.06 degrees (1 mil) in antenna bearing angle (See Table "SCR-584 Technical Characteristics"). Because the electrical beam width was 4 degrees (to the -3db or half-power points), the target would be smeared across a portion of a cylinder, so as to be wider in bearing than in range (i.e., on the order of 4 degrees, rather than 0.06 degrees implied by the mechanical pointing accuracy), for distant targets. Range information was displayed on two "J-scopes", similar to the more common A-line display, but arranged in a radial pattern timed to the return delay. One scope was used for coarse range, the other for fine.
https://en.wikipedia.org/wiki?curid=3972623
1,479,039
206,950
The Bazaar and caravanserai were constructed as an integral part of the complex, initially to provide the construction workers with accommodation and facilities for their wellbeing, and later as a place for trade, the revenue of which supplemented the expenses of the complex. The area became a small town in its own right during and after the building of the Taj. Originally known as 'Mumtazabad', today it is called Taj Ganji or 'Taj Market'. Its plan took the characteristic form of a square divided by two cross axial streets with gates to the four cardinal points. Bazaars lined each street and the resultant squares to each corner housed the caravanserais in open courtyards accessed from internal gates from where the streets intersected (Chauk). Contemporary sources pay more attention to the north eastern and western parts of the Taj Ganji (Taj Market) and it is likely that only this half received imperial funding. Thus, the quality of the architecture was finer than the southern half.
https://en.wikipedia.org/wiki?curid=13325558
206,843
1,149,169
Recent advances in health information technology have expanded the scope of health data. Advances in health information technology have fostered the eHealth paradigm, which has expanded the collection, use, and philosophy of health data. EHealth, a term coined in the health information technology industry, has been described in academia as an emerging field [at] the intersection of medical informatics, public health and business, referring to health services and information delivered or enhanced through the Internet and related technologies. In a broader sense, the term characterizes not only a technical development, but also a state-of-mind, a way of thinking, an attitude, and a commitment for networked, global thinking, to improve health care ... using information and communication technology.From the confluence of eHealth and mobile technology emerged mHealth, which is considered a subsector of eHealth. mHealth has been defined asmedical and public health practice supported by mobile devices ... . mHealth involves the use and capitalization on a mobile phone's core utility of voice and short messaging service (SMS) as well as more complex functionalities and applications including general packet radio service (GPRS), third and fourth generation mobile telecommunications (3G and 4G systems), global positioning system (GPS), and Bluetooth technology.The emergence of eHealth and mHealth have expanded the definition of health data by creating new opportunities for patient-generated health data (PGHD). PGHD has been defined as "health-related data—including health history, symptoms, biometric data, treatment history, lifestyle choices, and other information—created, recorded, gathered, or inferred by or from patients or their designees ... to help address a health concern." MHealth allows patients to monitor and report PGHD outside of a clinical setting. For example, a patient could use a blood monitor interfaced with their smartphone to track and distribute PGHD.
https://en.wikipedia.org/wiki?curid=55565558
1,148,562
1,210,073
Although MCA cards cost nearly double the price of comparable non-MCA cards, the marketing stressed that it was simple for any user to upgrade or add more cards to their PC, thus saving the considerable expense of a technician. In this critical area, Micro Channel architecture's biggest advantage was also its greatest disadvantage, and one of the major reasons for its demise. To add a new card (video, printer, memory, network, modem, etc.) the user simply plugged in the MCA card and inserted a customized floppy disk (that came with the PC) to blend the new card into the original hardware automatically, rather than bringing in an expensively trained technician who could manually make all the needed changes. All choices for interrupts (an often perplexing problem) and other changes were accomplished automatically by the PC reading the old configuration from the floppy disk, which made necessary changes in software, then wrote the new configuration to the floppy disk. In practice, however, this meant that the user must keep that "same floppy disk matched to that PC". For a small company with a few PCs, this was annoying, but practical. But for large organizations with hundreds or even thousands of PCs, permanently matching each PC with its own floppy disk was logistically unlikely or impossible. Without the original, updated floppy disk, no changes could be made to the PC's cards. After this experience repeated itself thousands of times, business leaders realized their dream scenario for upgrade simplicity did not work in the corporate world, and they sought a better process.
https://en.wikipedia.org/wiki?curid=140456
1,209,426
63,308
The word "quanta" (singular "quantum," Latin for "how much") was used before 1900 to mean particles or amounts of different quantities, including electricity. In 1900, the German physicist Max Planck was studying black-body radiation, and he suggested that the experimental observations, specifically at shorter wavelengths, would be explained if the energy stored within a molecule was a "discrete quantity composed of an integral number of finite equal parts", which he called "energy elements". In 1905, Albert Einstein published a paper in which he proposed that many light-related phenomena—including black-body radiation and the photoelectric effect—would be better explained by modelling electromagnetic waves as consisting of spatially localized, discrete wave-packets. He called such a wave-packet "a light quantum" (German: "ein Lichtquant").
https://en.wikipedia.org/wiki?curid=23535
63,283
1,705,322
Breslow was born in Rahway, New Jersey, the son of Gladys (Fellows) and Alexander E. Breslow. He was interested in the design and synthesis of new molecules with interesting properties, and the study of these properties. Examples include the cyclopropenyl cation, the simplest aromatic system and the first aromatic compound prepared with other than six electrons in a ring. His seminal contributions include the correct site of reactivity of thiamin diphosphate in enzymes that promote the decarboxylation of pyruvate – based on his pioneering use of proton NMR with small molecule analogues – and the rate enhancement provided by binding to cyclodextrins produced major themes for study in modern organic and biological chemistry. He also co-discovered the histone deacetylase inhibitor SAHA (Vorinostat) which is FDA-approved for the treatment of cutaneous T-cell lymphoma.
https://en.wikipedia.org/wiki?curid=4444424
1,704,366
1,330,796
The production of recombinant antibodies follows principally similar workflow. It consists of determining the sequence of the desired product followed by refinement of the codon, then gene synthesis and construct generation. Once the construct is delivered to the laboratory, expression constructs are produced, then they are transferred to a cell culture in the process called transfection and once the cell culture produces the desired recombinant antibody, it is regularly collected, purified and analyzed or used for further experimentation. For recombinant antibody production the stable cell lines such as CHO and HEK293 are used. Optimizations of mammalian cell cultures have led to increase the yield of antibodies from HEK293 or CHO cell lines to over 12g/liter. In the beginning phases of the recombinant antibody production it was important to achieve the assembly of a functional Fv fragment in "Escherichia coli". The correct fold is essential for functionality of the antibody. Second essential prerequisite for the modern day production of scFv was the successful assembly of recombinant antibodies from heavy and light chain of immunoglobulin. These two experiments allowed for further development and refinement of the recombinant antibodies until modern day form. Today's in vitro production process eliminates the need for laboratory animals. Using a synthetic or human Ab library, as opposed to immunization of animals and the subsequent generation of stable hybridoma cell lines, requires fewer resources and produces less waste, making the entire process more sustainable.
https://en.wikipedia.org/wiki?curid=54969945
1,330,067
909,962
In August 1941 a new squadron, No. 138 (Special Duties), was formed to undertake missions for the Special Operations Executive to maintain clandestine contact with the French Resistance. Among its aircraft were Lysander Mk.IIIs, which flew over and landed in occupied France. While general supply drops could be left to the rest of No. 138's aircraft, the Lysander could insert and remove agents from the continent or retrieve Allied aircrew who had been shot down over occupied territory and had evaded capture. For this role the Mk.IIIs were fitted with a fixed ladder over the port side to hasten access to the rear cockpit and a large drop tank under the belly. In order to slip in unobtrusively Lysanders were painted matte black overall (some early examples had brown/green camouflaged upper surfaces and later examples had grey/green upper surfaces); operations almost always took place within a week of a full moon, as moonlight was essential for navigation. The aircraft undertook such duties until the liberation of France in 1944.
https://en.wikipedia.org/wiki?curid=559595
909,483
185,011
QD color converter (QDCC) LED-backlit LCDs would use QD film or ink-printed QD layer with red/green sub-pixel patterned (i.e. aligned to precisely match the red and green subpixels) quantum dots to produce pure red/green light; blue subpixels can be transparent to pass through the pure blue LED backlight, or can be made with blue patterned quantum dots in case of UV-LED backlight. This configuration effectively replaces passive color filters, which incur substantial losses by filtering out 2/3 of passing light, with photo-emissive QD structures, improving power efficiency and/or peak brightness, and enhancing color purity. Because quantum dots depolarize the light, output polarizer (the analyzer) needs to be moved behind the color converter and embedded in-cell of the LCD glass; this would improve viewing angles as well. In-cell arrangement of the analyzer and/or the polarizer would also reduce depolarization effects in the LC layer, increasing contrast ratio. To reduce self-excitement of QD film and to improve efficiency, the ambient light can be blocked using traditional color filters, and reflective polarizers can direct light from the QDCC towards the viewer. As only blue or UV light passes through the liquid crystal layer, it can be made thinner, resulting in faster pixel response times.
https://en.wikipedia.org/wiki?curid=23692678
184,914
14,949
The genome of "Ramazzottius varieornatus," one of the most stress-tolerant species of tardigrades, was sequenced by a team of researchers from the University of Tokyo in 2015. While previous research had claimed that around one-sixth of the genome had been acquired from other organisms, it is now known that less than 1.2% of its genes were the result of horizontal gene transfer. They also found evidence of a loss of gene pathways that are known to promote damage due to stress. This study also found a high expression of novel tardigrade-unique proteins, including Damage suppressor (Dsup), which was shown to protect against DNA damage from X-ray radiation. The same team applied the Dsup protein to human cultured cells and found that it suppressed X-ray damage to the human cells by around 40%. While the exact mechanism of DNA protection is largely unknown, the results from an August 2020 study suggest that strong electrostatic attractions along with high protein flexibility help form a molecular aggregate, which allows Dsup to shield DNA.
https://en.wikipedia.org/wiki?curid=19817681
14,944
1,340,184
Given the complexity of building energy and mass flows, it is generally not possible to find an analytical solution, so the simulation software employs other techniques, such as response function methods, or numerical methods in finite differences or finite volume, as an approximation. Most of today's whole building simulation programs formulate models using imperative programming languages. These languages assign values to variables, declare the sequence of execution of these assignments and change the state of the program, as is done for example in C/C++, Fortran or MATLAB/Simulink. In such programs, model equations are tightly connected to the solution methods, often by making the solution procedure part of the actual model equations. The use of imperative programming languages limits the applicability and extensibility of models. More flexibility offer simulation engines using symbolic Differential Algebraic Equations (DAEs) with general purpose solvers that increase model reuse, transparency and accuracy. Since some of these engines have been developed for more than 20 years (e.g. IDA ICE) and due to the key advantages of equation-based modeling, these simulation engines can be considered as state of the art technology.
https://en.wikipedia.org/wiki?curid=43045000
1,339,451
678,538
Inspiration for the J-2 dates back to various NASA studies conducted in the late 1950s, of LH2-fuelled engines producing thrust of up to following the success of the RL-10 used on the Atlas-Centaur's Centaur upper stage. As ever-heavier launch vehicles entered consideration, NASA began to look at engines producing thrusts of up to , with development being officially authorized following the 1959 report of the Saturn Vehicle Evaluation Committee. A source evaluation board was formed to nominate a contractor from five bidding companies, and approval was given on 1 June 1960 for Rocketdyne to begin development of a "high-energy rocket engine, fuelled by LOX and hydrogen, to be known as the J-2". The final contract, awarded in September 1960, was the first to explicitly require the design "insure maximum safety for crewed flight."
https://en.wikipedia.org/wiki?curid=712786
678,184
56,850
Sonequa Martin-Green stars as Michael Burnham, captain of the "Discovery", along with the returning Doug Jones, Anthony Rapp, Mary Wiseman, Wilson Cruz, Blu del Barrio, David Ajala, and Tig Notaro. Active development on the season began by January 2020. More time was spent writing than previous seasons due to the COVID-19 pandemic, which inspired the space anomaly that the characters face in the season. Burnham's new role as captain is also explored following her promotion at the end of the . The fourth season was officially announced in October 2020, and filming took place in Toronto, Canada, from November 2020 to August 2021. New filming processes were implemented to ensure safety during the pandemic, which caused some production delays, and a video wall was constructed to allow for filming in front of real-time computer-generated backgrounds.
https://en.wikipedia.org/wiki?curid=63388083
56,826
1,792,977
After once again climbing a steep slope with "Gleichenia" thickets, one stands suddenly beneath the high enclosing rock wall of the mountain ring. The smooth water-washed stone seamed with water channels shows no variation in structure, and it appears almost as if the whole mountain was composed of a single monstrous block of rock. On this wall has been erected the steep 45 metre high rattan ladder; it is secured only at the bottom, in the middle and in the solid earth at the top, the rest lying free against the stone... Just above the middle of the ladder a small thin patch of humus is found, just sufficient to allow one to stand and rest for a moment. Both here, and at the top of the ladder a "Nepenthes" plant with unusually large pitchers has established itself. In the basal part, the pitchers are expanded into a jug shape. They are thus able, on the one hand, to take up a large quantity of water, and on the other, to hinder the escape of insects which have fallen inside, by means of the relatively narrow neck. [translated from the original Dutch and German in "Pitcher Plants of Borneo".]
https://en.wikipedia.org/wiki?curid=4676595
1,791,968
769,973
From 24 May to 1 November 2004, "John C. Stennis" conducted her fourth major overseas deployment, participating in Exercise Northern Edge 2004 in the Gulf of Alaska, Rim of the Pacific (RimPac) Exercise off Hawaii, exercises with "Kitty Hawk" off Japan and goodwill visits to Japan, Malaysia and Western Australia. Shortly after returning from deployment to San Diego, "JCS" changed her home port to Naval Station Bremerton, Washington on 19 January 2005. Once at Bremerton, "John C. Stennis" underwent an 11-month docking planned incremental availability (DPIA), the first time she had been dry-docked since commissioning. Upgrades included a new mast. The new mast's structure is the first of its kind. A new type of steel alloy was used, making it stiffer and thicker than before. The new mast is also heavier and taller, allowing it to support new antennae the old mast would not have been able to support. Other upgrades included the installation of a new integrated bridge system in the pilothouse that will save manpower and provide state-of-the-art displays.
https://en.wikipedia.org/wiki?curid=32069
769,559
1,374,219
After the first demonstration of the practical arc-mode caesium vapor thermionic converter by V. Wilson in 1957, several applications of it were demonstrated in the following decade, including its use with solar, combustion, radioisotope, and nuclear reactor heat sources. The application most seriously pursued, however, was the integration of thermionic nuclear fuel elements directly into the core of nuclear reactors for production of electrical power in space. The exceptionally high operating temperature of thermionic converters, which makes their practical use difficult in other applications, gives the thermionic converter decisive advantages over competing energy conversion technologies in the space power application where radiant heat rejection is required. Substantial thermionic space reactor development programs were conducted in the U.S., France, and Germany in the period 1963–1973, and the US resumed a significant thermionic nuclear fuel element development program in the period 1983–1993.
https://en.wikipedia.org/wiki?curid=1252913
1,373,461
965,130
Administration testimony sought to counteract these arguments. Defense Secretary Robert McNamara announced his "unequivocal support" for the treaty before the Foreign Relations Committee, arguing that US nuclear forces were secure and clearly superior to those of the Soviet Union, and that any major Soviet tests would be detected. Glenn T. Seaborg, the chairman of the AEC, also gave his support to the treaty in testimony, as did Harold Brown, the Department of Defense's lead scientist, and Norris Bradbury, the longtime director of the Los Alamos Laboratory. Maxwell D. Taylor, the Chairman of the Joint Chiefs of Staff, also testified in favor of the deal. Taylor and other members of the JCS, including Curtis LeMay, had made their support for the treaty conditional on four "safeguards": (1) a continued, aggressive underground testing program, (2) continued nuclear research programs, (3) continued readiness to resume atmospheric tests, and (4) improved verification equipment. Kennedy emphasized that the US would retain the ability to use nuclear weapons in war, would not be bound by the treaty if the Soviets violated it, and would continue an aggressive underground testing program. Kennedy also stressed that a ban would be a key step in preventing nuclear war.
https://en.wikipedia.org/wiki?curid=30592
964,621
1,098,065
Unsurprisingly, Ferranti won the contract for the radar component sometime in 1957 or 58. Shortly after the project started, in 1959 the project lead, Gus Scott, left for Hughes Microcircuits in nearby Glenrothes, and the team was taken over by Greg Stewart and Dick Starling. The initial system was built from a surplus AI.23B AIRPASS, and could be mounted to a trailer and towed by a Land Rover for testing. A significant issue is that the amount of signal returned varies greatly with the terrain; a building's vertical walls produces a partial corner cube that returns a signal that is about 10 million times stronger than the signal from sand or dry ground. To deal with the rapidly changing signals, an automatic gain control with 100 dB of range was developed.
https://en.wikipedia.org/wiki?curid=2220931
1,097,505
1,328,939
For CISH to work optimally, chromosomes must be in either interphase or metaphase. Tissue samples are securely attached to a surface, which is usually a glass slide, with paraffin. The tissue samples must then be washed and heated several times to remove any paraffin before the hybridization step. After this, the sample has to undergo pepsin digestion to ensure the target is accessible. As a final step, 10–20 μL of probe is added, the sample is covered with a coverslip which is sealed with rubber cement, and the slide is heated to 97 °C for 5–10 minutes to denature the DNA. The slide is then placed in a 37 °C oven overnight so that the probe can hybridize. On the next day, the sample is washed and a blocker for nonspecific protein binding sites is applied. If horseradish peroxidase (HRP) is going to be used, the sample must be incubated in hydrogen peroxide to suppress endogenous peroxidase activity. If digoxigenin was used as a probe label, an anti-digoxigenin fluorescein primary antibody followed by a HRP-conjugated anti-fluorescein secondary antibody are then applied. If biotin was used as a probe label, non-specific binding sites must first be blocked using bovine serum albumin (BSA). Then, HRP-conjugated streptavidin is used for detection. HRP then converts diaminobenzidine (DAB) into an insoluble brown product, which can be detected in a bright-field microscope under 40- to 60-fold magnification. A counterstain such as hematoxylin and eosin can be used to make the product more visible.
https://en.wikipedia.org/wiki?curid=24310754
1,328,211
465,462
"Agrobacterium"-mediated T-DNA transfer is widely used as a tool in biotechnology. For more than two decades, "Agrobacterium tumefaciens" has been exploited for introducing genes into plants for basic research as well as for commercial production of transgenic crops. In genetic engineering, the tumor-promoting and opine-synthesis genes are removed from the T-DNA and replaced with a gene of interest and/or a selection marker, which is required to establish which plants have been successfully transformed. Examples of selection markers include neomycin phosphotransferase, hygromycin B phosphotransferase (which both phosphorylate antibiotics) and phosphinothricin acetyltransferase (which acetylates and deactivates phosphinothricin, a potent inhibitor of glutamine synthetase) or a herbicide formulations such as Basta or Bialophos. Another selection system that can be employed is usage of metabolic markers such as phospho-mannose isomerase. "Agrobacterium" is then used as a vector to transfer the engineered T-DNA into the plant cells where it integrates into the plant genome. This method can be used to generate transgenic plants carrying a foreign gene. "Agrobacterium tumefaciens" is capable of transferring foreign DNA to both monocotyledons and dicotyledonous plants efficiently while taking care of critically important factors like the genotype of plants, types and ages of tissues inoculated, kind of vectors, strains of "Agrobacterium", selection marker genes and selective agents, and various conditions of tissue culture.
https://en.wikipedia.org/wiki?curid=779824
465,232
1,020,475
The theoretical biologist and philosopher of biology Joseph Henry Woodger led the introduction of positivism into biology with his 1929 book "Biological Principles". He saw a mature science as being characterised by a framework of hypotheses that could be verified by facts established by experiments. He criticised the traditional natural history style of biology, including the study of evolution, as immature science, since it relied on narrative. Woodger set out to play the role of Robert Boyle's 1661 "Sceptical Chymist", intending to convert the subject of biology into a formal, unified science, and ultimately, following the Vienna Circle of logical positivists like Otto Neurath and Rudolf Carnap, to reduce biology to physics and chemistry. His efforts stimulated the biologist J. B. S. Haldane to push for the axiomatisation of biology, and by influencing thinkers such as Huxley, helped to bring about the modern synthesis. The positivist climate made natural history unfashionable, and in America, research and university-level teaching on evolution declined almost to nothing by the late 1930s. The Harvard physiologist William John Crozier told his students that evolution was not even a science: "You can't experiment with two million years!"
https://en.wikipedia.org/wiki?curid=97536
1,019,948
5,693
. Darwin's belief that black people had the same essential humanity as Europeans, and had many mental similarities, was reinforced by the lessons he had from John Edmonstone in 1826. Early in the "Beagle" voyage, Darwin nearly lost his position on the ship when he criticised FitzRoy's defence and praise of slavery. He wrote home about "how steadily the general feeling, as shown at elections, has been rising against Slavery. What a proud thing for England if she is the first European nation which utterly abolishes it! I was told before leaving England that after living in slave countries all my opinions would be altered; the only alteration I am aware of is forming a much higher estimate of the negro character." Regarding Fuegians, he "could not have believed how wide was the difference between savage and civilized man: it is greater than between a wild and domesticated animal, inasmuch as in man there is a greater power of improvement", but he knew and liked civilised Fuegians like Jemmy Button: "It seems yet wonderful to me, when I think over all his many good qualities, that he should have been of the same race, and doubtless partaken of the same character, with the miserable, degraded savages whom we first met here."
https://en.wikipedia.org/wiki?curid=8145410
5,690
633,474
Sulfidic (or euxinic) conditions, which exist today in many water bodies from ponds to various land-surrounded mediterranean seas such as the Black Sea, were particularly prevalent in the Cretaceous Atlantic but also characterised other parts of the world ocean. In an ice-free sea of these supposed super-greenhouse worlds, oceanic waters were as much as higher, in some eras. During the timespans in question, the continental plates are believed to have been well separated, and the mountains as they are known today were (mostly) future tectonic events—meaning the overall landscapes were generally much lower— and even the half super-greenhouse climates would have been eras of highly expedited water erosion carrying massive amounts of nutrients into the world oceans fuelling an overall explosive population of microorganisms and their predator species in the oxygenated upper layers.
https://en.wikipedia.org/wiki?curid=1632974
633,136
174,307
Einsteinium was discovered as a component of the debris of the first hydrogen bomb explosion in 1952. Its most common isotope, einsteinium-253 (half-life 20.47 days), is produced artificially from decay of californium-253 in a few dedicated high-power nuclear reactors with a total yield on the order of one milligram per year. The reactor synthesis is followed by a complex process of separating einsteinium-253 from other actinides and products of their decay. Other isotopes are synthesized in various laboratories, but in much smaller amounts, by bombarding heavy actinide elements with light ions. Owing to the small amounts of produced einsteinium and the short half-life of its most easily produced isotope, there are currently almost no practical applications for it outside basic scientific research. In particular, einsteinium was used to synthesize, for the first time, 17 atoms of the new element mendelevium in 1955.
https://en.wikipedia.org/wiki?curid=9479
174,216
1,388,609
Enrichment is mandatory for student to undertake, this encourages pupils to partake supporting the programs success. There are a huge variety of courses for students to choose form including The Duke of Edinburgh's Award, sports, music and drama, information technology, voluntary services and The World Challenge; additionally students are free to start new courses on the proviso they can gain enough support for them. In 2011 a total of 79 different courses were available to students including 22 different sporting activates such as badminton, basketball, cycling, football (men and women’s), rugby (men and women’s), judo and squash and 9 different music groups. Alongside a variety of enrichment activities offered as part of the college programme, the music department offers annual opportunities for students across Kirklees to perform and compose. In 2018, the Greenhead College 'Carol for Yorkshire' raised over £700 for charity, and 2021 is the inaugural year of the Greenhead New Music Competition. Taster sessions are provided so that students can make informed decisions.
https://en.wikipedia.org/wiki?curid=1055782
1,387,839
653,056
Jackson's work in 2019 confirmed that Foote's experiments showing that water vapor and absorb heat occurred three years before Tyndall made a similar claim. He also validated that her observation that differences in atmospheric levels of water vapor and would result in climate change preceded Tyndall's claim by five years. Lorenz reported in 2019 in his work "Exploring Planetary Climate" that Foote had made her discoveries proving that moist air produced more warming than dry air, and that variances in air density impacted warming, prior to Tyndall. Perlin concurred, describing Foote as "the Rosa Parks of science, … the first woman to have a paper read at a major scientific meeting… first woman to have a paper published in the proceedings of a major scientific meeting… [and] the only woman to be published in serious physics journals until Madame Curie". Ortiz and Jackson concluded that Foote was the first to demonstrate absorption of heat by carbon dioxide and water vapor, but she did not isolate or detect the absorption and emission of radiant energy within the thermal infrared range, which causes the greenhouse effect.
https://en.wikipedia.org/wiki?curid=49280323
652,713
288,462
The Trident programme was projected to cost £5 billion, including the four submarines, the missiles, new facilities at Coulport and Faslane and the contribution to Trident II D-5 R&D. It was expected to absorb 5 per cent of the defence budget. As with Polaris, the option for a fifth submarine (allowing two to be on patrol at all times) was discussed, but ultimately rejected. Thatcher's popularity soared as a result of the British victory in the Falklands War, in which the ships that the Americans had insisted be retained played a crucial part. Trident's future was secured the following year when the Conservative Party won the 1983 general election, defeating a Labour Party that had pledged to cancel Trident. The first Trident boat, was ordered on 30 April 1986. In view of the Labour Party's continued opposition to Trident, Vickers insisted that the contract include substantial compensation in the event of cancellation.
https://en.wikipedia.org/wiki?curid=9095461
288,305
1,315,296
If formula_19 and formula_20 are even moderately large then we will have to resort to an approximation to formula_21 . Consider the following Markov chain on formula_12. Fix formula_23 and set formula_24 where formula_25 is an arbitrary proper configuration. Randomly choose a point formula_26 and independently draw formula_27. If formula_28 and all of the adjacent points are black then color formula_29 white leaving all other points alone. Otherwise, color formula_29 black and leave all other points alone. Call the resulting configuration formula_31. Continuing in this fashion yields a Harris ergodic Markov chain formula_32 having formula_33 as its invariant distribution. It is now a simple matter to estimate formula_34 with formula_35. Also, since formula_12 is finite (albeit potentially large) it is well known that formula_11 will converge exponentially fast to formula_33 which implies that a CLT holds for formula_39.
https://en.wikipedia.org/wiki?curid=60544754
1,314,575
510,249
During World War II, Rothschild was recruited to work at Bletchley Park on codebreaking with Alan Turing and was awarded a Defence Medal from the British government for her efforts. Additionally, she pressed the UK Government to admit more German Jews as refugees from Nazi Germany. She arranged housing for 49 Jewish children, some of whom stayed at her home at Ashton Wold. The estate also served as a hospital for wounded military personnel, including her future husband, Captain George Lane. Lane, a Hungarian-born British soldier, had changed his name from Lanyi in case of enemy capture. They had six children, four biological: Mary Rozsiska (1945–2010), Charles Daniel (born 1948), Charlotte Teresa (born 1951) and Johanna Miriam (born 1951); and two adopted. The marriage was dissolved in 1957 but the pair remained on good terms.
https://en.wikipedia.org/wiki?curid=873363
509,984
273,571
The black‐footed ferret experienced a recent population bottleneck in the wild followed by a more than 30-year recovery through "ex situ" breeding and then reintroduction into its native range. As such, this sole endemic North American ferret allows examining the impact of a severe genetic restriction on subsequent biological form and function, especially on reproductive traits and success. The black‐footed ferret was listed as endangered by the United States Fish and Wildlife Service (USFWS) in 1967. Declared extinct in 1979, a residual wild population was discovered in Meeteetse, Wyoming, in 1981. This cohort eventually grew to 130 individuals and was then nearly extirpated by sylvatic plague, "Yersinia pestis", and canine distemper virus, "Canine morbillivirus", with eventually 18 animals remaining. These survivors were captured from 1985 to 1987 to serve as the foundation for the black‐footed ferret "ex situ" breeding program. Seven of those 18 animals produced offspring that survived and reproduced, and with currently living descendants, are the ancestors of all black‐footed ferrets now in the "ex situ" (about 320) and "in situ" (about 300) populations.
https://en.wikipedia.org/wiki?curid=234031
273,423
172,715
Synthetic fuel grades included "T.L. [jet] fuel", "first quality aviation gasoline", "aviation base gasoline", and "gasoline - middle oil"; and "producer gas" and diesel were synthesized for fuel as well (converted armored tanks, for example, used producer gas). By early 1944 German synthetic-fuel production had reached more than from 25 plants, including 10 in the Ruhr Area. In 1937 the four central Germany lignite coal plants at Böhlen, Leuna, Magdeburg/Rothensee, and Zeitz, along with the Ruhr Area bituminous coal plant at Scholven/Buer, produced of fuel. Four new hydrogenation plants () were subsequently erected at Bottrop-Welheim (which used "Bituminous coal tar pitch"), Gelsenkirchen (Nordstern), Pölitz, and, at 200,000 tons/yr Wesseling. Nordstern and Pölitz/Stettin used bituminous coal, as did the new Blechhammer plants. Heydebreck synthesized food oil, which was tested on concentration camp prisoners. After Allied bombing of Germany's synthetic-fuel production plants (especially in May to June 1944), the Geilenberg Special Staff used 350,000 mostly foreign forced-laborers to reconstruct the bombed synthetic-oil plants, and, in an emergency decentralization program, the (1944-1945), to build 7 underground hydrogenation plants with bombing protection (none were completed). (Planners had rejected an earlier such proposal, expecting that Axis forces would win the war before the bunkers would be completed.) In July 1944 the "Cuckoo" project underground synthetic-oil plant (800,000 m) was being "carved out of the Himmelsburg" north of the Mittelwerk, but the plant remained unfinished at the end of World War II. Production of synthetic fuel became even more vital for Nazi Germany when Soviet Red Army forces occupied the Ploiești oilfields in Romania on 24 August 1944, denying Germany access to its most important natural oil source.
https://en.wikipedia.org/wiki?curid=2170613
172,624
199,979
The late 17th and early 18th centuries saw the achievements of Cambridge University physicist and mathematician Sir Isaac Newton (1642-1727). Newton, a fellow of the Royal Society of England, combined his own discoveries in mechanics and astronomy to earlier ones to create a single system for describing the workings of the universe. Newton formulated three laws of motion which formulated the relationship between motion and objects and also the law of universal gravitation, the latter of which could be used to explain the behavior not only of falling bodies on the earth but also planets and other celestial bodies. To arrive at his results, Newton invented one form of an entirely new branch of mathematics: calculus (also invented independently by Gottfried Leibniz), which was to become an essential tool in much of the later development in most branches of physics. Newton's findings were set forth in his "Philosophiæ Naturalis Principia Mathematica" ("Mathematical Principles of Natural Philosophy"), the publication of which in 1687 marked the beginning of the modern period of mechanics and astronomy.
https://en.wikipedia.org/wiki?curid=13758
199,876
1,149,570
A variety of bichrome and polychrome vessels have also been found at Moundville. Stylistically they closely resemble pottery found along the Tennessee, Cumberland, the lower Ohio River and the central Mississippi Valleys. This pottery was long thought to have been imported from these other areas as trade items, and modern chemical analysis has shown that much of it is. The same analysis has also proved that some of the pottery was made locally in the Moundville polity. The polychrome pottery has representational motifs painted with red, white, and black pigments. The red and white are applied as slips of colored clay, while the black was made from carbon and applied with a negative or resist technique. Similar in manufacture to the engraved ceramics, the painted pottery has thin walls, was tempered with finely ground mussel shell and was given a polished exterior. This style comes in two major shapes, a bottle with a spherical body and a narrow curving neck and a terraced rectangular bowl that is a Moundville specialty. The rectangular bowl is a vertical-sided, flat-bottomed, rectangular vessel with an eccentric rim, specifically with one side lower than the other three so as to display the containers contents. The designs painted on the rectangular vessels are similar to motifs found on other locally produced wares and include the oblong emblem with an embedded cross-in-circle motif(thought to be a graphic representation of a scalp stretched on a hoop), the hand, the skull, the ogee, concentric circles, rayed concentric circles, rayed semicircles, and rayed spirals.
https://en.wikipedia.org/wiki?curid=28080740
1,148,963
510,308
The island of Biak forms part of the Schouten Islands, and dominates the entrance to Geelvink Bay, near the western end of New Guinea; its terrain and location about from Hollandia and from Sarmi (where the Japanese had begun concentrating supply bases and airfields), made it well suited to airfield construction, particularly in the flatter southeastern area. As a result, as the Allies began their advance towards the Philippines in 1944, General Douglas MacArthur's Southwest Pacific command began planning its capture. In conceptualizing the operation, Allied planners envisaged a week-long operation; estimating that there were up to 2,000 Japanese troops defending the area. Four landing beaches were chosen near Bosnek, designated Green 1, 2, 3 and 4. Allied planners considered these beaches to be poorer for landing operations, compared to those further away from the airfields, but they were chosen due to their proximity to the main Allied objectives and because aerial reconnaissance indicated that the beaches were not backed by cliffs or swamps, and that there were two jetties nearby that might facilitate deep-water port access.
https://en.wikipedia.org/wiki?curid=7163666
510,043
917,422
Before the advent of computer-generated imagery (CGI), visual effects of vehicles such as marine ships and space ships were created by filming "miniature" models. These were considerably larger scale than hobby versions to allow inclusion of a high degree of surface detail, and electrical features such as interior lighting and animation. For "", a pre-production model was created in December 1964, mostly of pine, with Plexiglass and brass details, at a cost of $600. This was followed by a production model constructed from plaster, sheet metal, and wood, at ten times the cost of the first. As the "Enterprise" was originally reckoned to be long, this put the models at 1:344 and 1:83.9 scale respectively. The Polar Lights company sells a large plastic "Enterprise" model kit essentially the same size as the first TV model, in 1:350 scale (32 inches long). It can be purchased with an optional electronic lighting and animation (rotating engine domes) kit.
https://en.wikipedia.org/wiki?curid=297672
916,939
793,733
Most phylogenetic analyses suggest that radiodonts, alongside opabiniids ("Opabinia" and "Utaurora"), are stem-group arthropods just basal to deuteropoda, a clade including upper stem (e.g. fuxianhuiids and bivalved arthropods) and crown Euarthropoda (e.g. Artiopoda, Chelicerata and Mandibulata). This interpretation is supported by numerous arthropod groundplan found on radiodonts and opabiniids, such as stalked compound eyes, digestive glands, trunk appendages forming by dorsal and ventral elements (precursor of arthropod biramous appendages). Compared to opabiniids, which possess posterior mouth opening and fused frontalmost appendages (comparable to euarthropod posterior-facing labrum/hypostome complex), radiodonts on the other hand featured euarthropod-like dorsal sclerite (H-element) and arthropodization (frontal appendages) on their head regions, alongside cuticularized gut termini. The fact that both radiodonts and opabiniids lack exoskeleton on their trunk region suggests that the origin of compound eyes and arthropodization (segmented appendages) precede arthrodization (full set of trunk exoskeleton) in the arthropod stem lineage. The constricted neck region with feeding appendicular structures of some radiodont may also shed light on the origin of the sophisticated arthropod head, which was formed by the fusion of multiple anterior body segments. Basal deuteropods that possess a mixture of radiodont/opabiniid characters like "Kylinxia" and "Erratus", may represent intermediate forms between radiodonts, opabiniids and other euarthropods.
https://en.wikipedia.org/wiki?curid=21708650
793,308
1,968,306
Clayton, Colgate and Fishman's 1969 prediction that motivated pursuing gamma-ray-line astronomy as an empirical test of supernova nucleosynthesis was recognized in the American Astronomical Society Centennial Volume as one of the 50 most influential astrophysics papers of the 20th century. Observational discovery of those gamma rays would later confirm explosive nucleosynthesis theory and cement mankind's understanding of the profoundly radioactive nature of supernovae. It is the innovation for which Clayton is best known. His NASA-funded research at Rice University during the 1970s sought after additional nuclear prospects for that high-energy spectroscopic astronomy, which is based on the recognizable energies of gamma rays emitted by individual radioactive nuclei that had recently been ejected from supernovae. Today it has blossomed with many observational results after quickly becoming a goal for future space astronomy missions, especially at a time when Compton Gamma Ray Observatory was being proposed to NASA in 1977 (launched by Space Shuttle "Atlantis" in 1991). Hopes were suddenly raised for a detectable source when in 1987 optical astronomers discovered a nearby supernova called SN1987A in the Large Magellanic Cloud. Clayton described those hopes from his 1987 sabbatical-year office at Durham University UK as a mounting excitement generated by observed X-ray emission from its supernova surface. His research with L-S The augmented understanding of those hard X-rays and their derivation from the radioactivity gamma rays permeating supernova interiors. Supernova 1987A gamma-ray-line emission did yield exciting first detections of those gamma-ray lines from Co and from Co (by OSSE with Clayton a coauthor) thereby establishing this field of astronomy. The Compton Gamma Ray Observatory, the space gamma-ray telescope mission that detected several predicted gamma-ray lines, was the second mission of NASA's Great Observatories program.
https://en.wikipedia.org/wiki?curid=36061850
1,967,175
955,638
There are a number of physical factors that may cause sexual discomfort. Pain is sometimes experienced in the testicular or glans area of the penis immediately after ejaculation. Infections of the prostate, bladder, or seminal vesicles can lead to intense burning or itching sensations following ejaculation. Patients with interstitial cystitis may experience intense penis pain at the moment of ejaculation. Gonorrheal infections are sometimes associated with burning or sharp penile pains during ejaculation. Urethritis or prostatitis can make genital stimulation painful or uncomfortable. Anatomic deformities of the penis, such as exist in Peyronie's disease, may also result in pain during coitus. One cause of painful intercourse is due to the painful retraction of a too-tight foreskin, occurring either during the first attempt at intercourse or subsequent to tightening or scarring following inflammation or local infection. Another cause of painful intercourse is due to tension in a short and slender frenulum, frenulum breve, as the foreskin retracts on entry to the vagina irrespective of lubrication. In one study frenulum breve was found in 50% of patients who presented with dyspareunia. During vigorous or deep or tight intercourse or masturbation, small tears may occur in the frenum of the foreskin and can bleed and be very painful and induce anxiety, which can become chronic if left unresolved. If stretching fails to ease the condition, and uncomfortable levels of tension remain, a frenuloplasty procedure may be recommended. Frenuloplasty is an effective procedure, with a high chance of avoiding circumcision, giving good functional results and patient satisfaction. The psychological effects of these conditions, while little understood, are real, and are visible in literature and art.
https://en.wikipedia.org/wiki?curid=292107
955,133
1,078,611
DQ3.3 is shorthand for the DQ α3β3 heterodimeric isoform. The isoform is encoded almost exclusively by the DQA1:DQB1 haplotype. The haplotype is linked to DR7. A small percentage of coeliac disease are associated with this haplotype, and some disease causing gliadins are presented by DQ3.3. The haplotype is found at high frequencies in the Mediterranean and West Africa. The Eurasian geographic distribution of DQ2.2 is slightly greater than DQ2.5. Compared to DQ2.5, the frequency in Sardinia is low, but in Iberia it is high reaching a maximum frequency of ~30% in Northern Iberia, and half that in the British Isles. It extends along the Mediterranean and Africa at relatively high frequency and is found in high frequencies in some Central Asian, Mongolians, and Han Chinese. It does not appear to have an indigenous presence in the West Pacific Rim or the New World and DQ2.2 presence in Southeast Asia and Indonesia is likely the result of gene flow from India and China in post-neolithic times. The haplotype shows considerable diversity in Africa and this has translated to Iberia with 2 addition haplotypes, DQA1:DQB1 and DR7:DQA1:DQB1. The expansion of DQ2.2 into Europe appears to have been slightly later or biased by some constriction between Iberia and the rest of the continent.
https://en.wikipedia.org/wiki?curid=12823655
1,078,056
1,570,982
Among the mechanisms cited for this greater productivity are more sophisticated transcriptional controls, multifunctional proteins, more interaction between protein products, alternative splicing and post-translational modifications that may produce several protein products from the same genetic raw material. In addition, thousands of non-coding RNAs that are transcribed from DNA but not translated into protein have emerged as important regulators of gene expression and development in humans and other eukaryotes. They include short RNA sequences, such as microRNAs (miRNAs), small interfering RNAs (siRNAs) and Piwi-interacting RNAs (piRNAs), and long, non-coding RNAs (lncRNA) that may regulate gene expression at different stages of development. Some researchers suggest that instead of the number of genes the focus now should shift to gene interactions and the network of genetic regulatory mechanisms that allow them to support a variety of biological activities. These transitions have taken analysis of genetic complexity from the C-value to the G-value to what some refer to as the I-value, a measure of the total information contained in a genome.
https://en.wikipedia.org/wiki?curid=61892438
1,570,094
736,910
For structural engineering and analysis, immersive environments enable the user to focus on structural investigations without getting too distracted to operate and navigate the simulation tool. Virtual and augmented reality applications have been designed for finite element analysis of shell structures. Using stylus and data gloves as input devices, the user can create, modify mesh, and specify boundary conditions. For a simple geometry, real-time color-coded results are obtained by changing loads on the model. Studies have used artificial neural networks (ANN) or approximation methods to achieve real-time interaction for the complex geometry, and to simulate its impact via haptic gloves. Large scale structures and bridge simulation have also been achieved in immersive virtual environments. The user can move the loads acting on the bridge, and finite element analysis results are updated immediately using an approximate module.
https://en.wikipedia.org/wiki?curid=10499965
736,522
428,032
In an attempt to provide a clear assessment of the theory that a purely physical facial change, involving only certain facial muscles, can result in an emotion, Strack, Martin, & Stepper (1988) devised a cover story that would ensure the participants adopt the desired facial posing without being able to perceive either the corresponding emotion or the researchers' real motive. Told they were taking part in a study to determine the difficulty for people without the use of their hands or arms to accomplish certain tasks, participants held a pen in their mouth in one of two ways. The Lip position would contract the orbicularis oris muscle, resulting in a frown. The Teeth position would cause the zygomaticus major or the risorius muscle, resulting in a smile. The control group would hold the pen in their nondominant hand. All had to fill a questionnaire in that position and rate the difficulty involved. The last task, which was the real objective of the test, was the subjective rating of the funniness of a cartoon. The test differed from previous methods in that there were no emotional states to emulate, dissimulate or exaggerate.
https://en.wikipedia.org/wiki?curid=9284012
427,822
1,394,808
Underwater diving interventions, particularly on scuba, provide the capacity for scientists to make direct observations on site and in real time, which allow for ground-truthing of larger scale observations and occasional serendipitous observations outside the planned experiment. Human dexterity remains less expensive and more adaptable to unexpected complexities in experimental setup than remotely operated and robotic alternatives in the shallower depth ranges. Scuba has also provided insights which would be unlikely to occur without direct observation, where hypotheses produced by deductive reasoning have not predicted interactive and behavioural characteristics of marine organisms, and these would not be likely to be detected from remote sensing or video or other methods which do not provide the full context and detail available to the diver. Scuba allows the scientist to set up the experiment and be present to observe unforeseen alternatives to the hypothesis.
https://en.wikipedia.org/wiki?curid=11319315
1,394,037
2,116,444
Kōzō Sasaki was born the third son of a impoverished farming family in Miyagi prefecture on May 25, 1900. Sasaki was born while his parents were on the run for having eloped without permission, so he was not entered into a proper family registry until he was 11 years old and therefore could not enroll in regular school until that time. Instead of going to school, he performed hard manual labor, such as manufacturing charcoal. As a teenager, he went to Sendai city to work in a silk mill, saving up money to go to Tokyo for study. He graduated from Nihon University's 2-year junior college with a degree in politics in 1928. It was at Nihon University that Sasaki first became exposed to socialist ideas and became involved in the Japanese labor movement. Returning to Sendai, he got a job in a bicycle factory, but was fired almost immediately for attempting to organize a strike. Thereafter, he became an activist in the Labor-Farmer Movement and became a leader in instigating contentious tenant-landlord disputes, leading to physical brawls with police and multiple arrests.
https://en.wikipedia.org/wiki?curid=13403447
2,115,227
1,709,826
Disseminated BCG infections occur in infants with SCID or with other severe T cell defects. However, in approximately half of the cases no specific host defect has been found. One possible explanation for this predilection was found in a 2.5-month-old Tunisian female infant who had fatal idiopathic disseminated BCG infection. In four children from Malta who had disseminated atypical mycobacterial infection in the absence of a recognized immunodeficiency. In the case of all five children, there was consanguinity in their pedigrees. All affected were found to have a functional defect in the upregulation of TNFα production by their blood macrophages in response to stimulation with IFNγ. Furthermore, all lacked expression of IFNγR's on their blood monocytes or lymphocytes, and each was found to have a mutation in the gene on chromosome 6q22-q23 that encodes IFNγR1. Of interest, these children did not appear to be susceptible to infection with agents other than mycobacteria. Th1 responses appeared to be normal in these patients. The susceptibility of these children to mycobacterial infections thus apparently results from an intrinsic impairment of the IFNγ pathway response to these particular intracellular pathogens, showing that IFNγ is obligatory for efficient macrophage antimycobacterial activity. Since the initial discoveries of IFNγR1-deficient humans, many more examples have been found, and IFNγR2-deficient individuals have been found as well.
https://en.wikipedia.org/wiki?curid=9753004
1,708,867
835,557
BSR and TSR occur at different depths. BSR takes place in low-temperature environments, which are shallower settings such as oil and gas fields. BSR can also take place in modern marine sedimentary environments such as stratified inland seas, continental shelves, organic-rich deltas, and hydrothermal sediments which have intense microbial sulfate reduction because of the high concentration of dissolved sulfate in the seawater. Additionally, the high amounts of hydrogen sulfide found in oil and gas fields is thought to arise from the oxidation of petroleum hydrocarbons by sulfate. Such reactions are known to occur by microbial processes but it is generally accepted that TSR is responsible for the bulk of these reactions, especially in deep or hot reservoirs. Thus, TSR occurs in deep reservoirs where the temperatures are much higher. BSR is geologically instantaneous in most geologic settings, while TSR occurs at rates in the order of hundreds of thousands of years. Although much slower than BSR, even TSR appears to be a geologically fairly fast process.
https://en.wikipedia.org/wiki?curid=2465352
835,108
2,046,433
Flows were first introduced for large deformations in image matching; formula_19 is the instantaneous velocity of particle formula_20 at time formula_21. with the vector fields termed the Eulerian velocity of the particles at position of the flow. The modelling approach used in CA enforces a continuous differentiability condition on the vector fields by modelling the space of vector fields formula_22 as a reproducing kernel Hilbert space (RKHS), with the norm defined by a 1-1, differential operatorformula_23, Green's inverse formula_24. The norm according to formula_25 where for formula_26 a generalized function or distribution, then formula_27 on formula_28, and the conditional density on the observable imagery formula_29, conditioned on formula_30. For images with diffeomorphism group action formula_31, then the prior on the group formula_32 induces the prior on images formula_33, written as densities the log-posterior takes the form
https://en.wikipedia.org/wiki?curid=49344993
2,045,252
2,096,568
After Huet returned as chief, the academy began a fruitful period of work, and began to be recognized by scholars throughout Europe, particularly in England, where the members of the Royal Academy were interested in the effects of royal support on science in France. Dissections of animals, particularly sea creatures, taking advantage of Caen's proximity to the water, as well as the desalinization project continued. However, Huet again left Caen and the group's participation began to drop off, leaving the academy on the brink of failure. In November, 1668, Chamillart reappeared and retained royal funding for the academy, which reenergized the group. The seawater desalinization program was also completed and presented to the Académie Royal, prompting additional funding by the court. This funding brought additional problems, as it removed Huet as the major patron, prompting Huet to charge the academy rent for its meeting space in his home. The members also began to argue over how the remaining funds should be spent, which further escalated tensions between Graindorge and the other members. A delay in receiving the royal funds, as well as difficulties in establishing a regular meeting place, caused the group to begin to break apart. In early 1672, Graindorge attempted to reunite the group around a new project, a study of the scoter that would disprove the theory that the birds come from the barnacles of ship, a belief also promoted by the church. He worked on the project himself, wrote up his findings, and had Chamillart take them to Paris for submission to the Académie Royal and the court, which rejected his submission. This prompted the court to cease funding the academy, causing it to disband in late 1672.
https://en.wikipedia.org/wiki?curid=31093370
2,095,360
2,029,579
The building plans for the UNC-CSI campus were designed considering guidelines set forth by the LEED program. Designers focused heavily on low energy use and water conservation. The campus contains sustainable features, including the building itself and the landscape design throughout the campus. The UNC-CSI building is LEED Gold certified (the second highest certification possible). LEED scores on a point system, from 40 (standard certification) to 80+ points for a Platinum certification. UNC-CSI was awarded 64 points and a Gold certification in 2014. The designers achieved this by integrating sustainable building materials and sustainable technologies. There are six categories in which LEED scores on, UNC-CSI’s campus scored in all categories, the first being alternative transportation. This includes bicycle storage and preferred parking for low emission and carpool vehicles. On storm-water management and landscape design, 71% of the site is open space. The energy consumption is reduced by 37% and portable water consumption is reduced by 75%. 24% of the building materials are recycled and 75% of on-site waste was also recycled. The UNC Coastal Studies Institute was also designed for 95% of occupiable space to be exposed to daylight.
https://en.wikipedia.org/wiki?curid=56311333
2,028,411
2,014,457
During the 1760s he used his aristocratic connections to tour mines throughout the Lowlands and to assemble his own sizeable mineralogical collection. By the mid-1760s, Walker was known as one of Scotland's leading lay naturalists. This motivated the Church of Scotland and the Board of Annexed Estates to send him on exploratory tours of the Highland and Hebrides in 1764 and 1771. These tours allowed him to make religious and ethnographic observations for the church and to take scientifically oriented notes on northern Scotland's minerals, plants, animals, and climate. In his 1764 tour, while on visit to the island of Jura (Deer Island), Walker may have made the first detailed description of the Lyme disease. He gives a good description both of the symptoms (with "exquisite pain [in] the interior parts of the limbs") and of the tick vector itself, which he describes as a "worm" with a body which is "of a reddish colour and of a compressed shape with a row of feet on each side" that "penetrates the skin". It was also during this period that he collected samples of the mineral which came to be known as strontianite from its type locality, thus setting in process the identification and analysis of the new alkaline earth Strontium.
https://en.wikipedia.org/wiki?curid=635652
2,013,298
471,183
The Lunar Crater Observation and Sensing Satellite (LCROSS) was a robotic spacecraft operated by NASA to perform a lower-cost means of determining the nature of hydrogen detected at the polar regions of the Moon. The main LCROSS mission objective was to explore the presence of water ice in a permanently shadowed crater near a lunar polar region. LCROSS was launched together with the Lunar Reconnaissance Orbiter (LRO) on 18 June 2009, as part of the shared Lunar Precursor Robotic Program. LCROSS was designed to collect and relay data from the impact and debris plume resulting from the launch vehicle's spent Centaur upper rocket stage striking the crater Cabeus near the south pole of the Moon. Centaur impacted successfully on 9 October 2009, at 11:31 UTC. The "shepherding spacecraft" (carrying the LCROSS mission payload) descended through Centaur's plume of debris, and collected and relayed data before impacting six minutes later at 11:37 UTC. The project was successful in discovering water in Cabeus.
https://en.wikipedia.org/wiki?curid=184638
470,947
1,438,098
The desire for more advanced weapons during World War I inspired significant investments in scientific research and applied engineering in both Germany and allied countries. World War II spawned even more widespread scientific research and engineering development in such fields as nuclear chemistry and nuclear physics as scientists raced to contribute to the development of radar, the proximity fuse, and the atomic bomb. In Germany, scientists such as Werner Heisenberg were being pushed by the leaders of the German war effort, including Adolf Hitler to evaluate the feasibility of developing atomic weapons in time for them to have an effect on the outcome of the war. Meanwhile, allied countries in the late 1930s and 1940s committed monumental resources to wartime scientific research. In the United States, these efforts were initially led by the National Defense Research Committee. Later, the Office of Scientific Research and Development, organized and administered by the MIT engineer Vannevar Bush, took up the effort of coordinating government efforts in support of science.
https://en.wikipedia.org/wiki?curid=5788461
1,437,288
383,038
While the pre-operative alpha and beta blockade discussed above is overwhelmingly recognized as the standard of care, particularly in the United States, there has been discussion at the international level if a blockade is necessary. In 2017, a team of researchers from Germany published an observational case series that called into question the current recommendations for a blockade. The study examined the intraoperative maximal systolic arterial pressure in people with and without alpha-adrenoceptor blockade and found no difference in complications between the two groups. The following year, a group from France published a similar article with a warning against waiting an entire week to begin alpha-blockade. The French researchers called for immediate surgical intervention and consideration of steps to mitigate any intraoperative catecholamine crisis. These articles resulted in rebuttals from research teams in the United States, but an international consensus has not yet been reached.
https://en.wikipedia.org/wiki?curid=277088
382,843
957,107
This incident causes Katarn to distance himself from the Force and return to mercenary missions with Jan Ors. In "Jedi Outcast", Ors is captured by Desann, a former pupil of Luke Skywalker who has turned to the Dark Side. Katarn believes Desann to have killed Ors, and so he returns to the Valley of the Jedi in an attempt to reconnect to the Force so as to stop Desann. Eventually, it is revealed that Ors' death is a ruse by Desann for the express purpose of having Katarn return to the Valley, so Desann may learn of its location. Desann, in league with the Imperial Remnant, uses the power of the Valley to endow his troops with Force power, before using them to launch an attack on the Jedi Academy. However, Katarn defeats Desann and discovers his true path, becoming a tutor at the Academy. In "Jedi Academy", Katarn takes on two students: Jaden Korr and Rosh Penin. The protagonist of the game is Jaden, who is dispatched on various peace-keeping missions across the galaxy, sometimes with Katarn, sometimes alone. Jaden eventually encounters a Sith cult led by Tavion (Desann's former apprentice) who plans to restore the Sith to power by using stolen Force energy to resurrect an ancient Sith Lord, Marka Ragnos. After learning that Rosh has betrayed the Jedi and joined Tavion, Jaden may either kill him and turn to the Dark Side or let him live and remain on the Light Side. If Jaden chooses the Dark Side, he/she kills Tavion, defeats Katarn, and flees with Tavion's staff, which is capable of absorbing the Force. The game ends with Katarn setting out in pursuit of Jaden. If Jaden chooses to spare Rosh, he/she ultimately defeats both Tavion and the spirit of Ragnos, and is lauded for his/her actions by Katarn and Luke.
https://en.wikipedia.org/wiki?curid=14180189
956,601
778,618
One effect of digital operation that rarely appeared in analog circuits was cathode poisoning. Vacuum tubes that operated for extended intervals with no plate current would develop a high-resistivity layer on the cathodes, reducing the gain of the tube. Specially selected materials were required for computer tubes to prevent this effect. To avoid mechanical stresses associated with warming the tubes to operating temperature, often the tube heaters had their full operating voltage applied slowly, over a minute or more, to prevent stress-related fractures of the cathode heaters. Heater power could be left on during standby time for the machine, with high-voltage plate supplies switched off. Marginal testing was built into sub-systems of a vacuum-tube computer; by lowering plate or heater voltages and testing for proper operation, components at risk of early failure could be detected. To regulate all the power-supply voltages and prevent surges and dips from the power grid from affecting computer operation, power was derived from a motor-generator set that improved the stability and regulation of power-supply voltages.
https://en.wikipedia.org/wiki?curid=47825879
778,201
1,668,436
The "Skolithos linearis" ichnogenus was first described in 1840, by Samuel Stehman Haldeman, a renowned Pennsylvania naturalist in the early 19th century, who labeled the structure as the “oldest fossil in the state”. He named the trace fossil "Skolithos" meaning “worm-stone”, suggesting that it may have been a product of animal activity rather than a floral origin. James Hall published the first illustrations of Haldeman’s discovery in his journal "Paleontology of New York Volume I" (1847) coining it the Latin term "Skolithus".  1943 marked the revival of Haldeman’s research as Benjamin Howell reported the occurrence of the trace fossil in the Hardyston Formation in Pennsylvania. Howell retitled the ichnogenus "Skolithos" in accordance with the appropriate ichnotaxon nomenclature. In the 1960s structural geologists discovered the use of the trace fossil as a strain marker by which it could record rotation and strain in highly deformed rocks. This led to a series of experiments that extend to present day analyses to determine the extent of the strain marking properties of "Skolithos" burrows. "Skolithos linearis", found in the Blue Ridge Mountain region, is the oldest known trace fossil in Virginia. "Trypanites" is similar in form but is excavated in hard substrates. Also somewhat similar are "Ophiomorpha" and "Diplocraterion".
https://en.wikipedia.org/wiki?curid=17037490
1,667,497
1,179,733
On December 9, 1956, Trans-Canada Air Lines Flight 810, a North Star airplane crashed on the upper slopes of the mountain, killing all 62 people aboard. This was one of the world's worst air disasters up to that time. Prominent among the dead were team members of the Winnipeg Blue Bombers and Saskatchewan Roughriders, on their way home from the annual East-West All-Star Game in Vancouver. A memorial to the dead can be found on a spur road just above the Chilliwack River Road. The site itself was supposed to have been consecrated by the Cemeteries Act after the discovery of the crash site and associated human remains, some of which were gathered into a common grave. Others found by climbers and hikers have been placed in a "shrine" out of the weather in a discreet location. In the 1990s the provincial government, under pressure from the Families of Slesse organization, finally passed legislation to enshrine protection of the site, which was under threat from clearcut logging at the time, and markers have been placed on trails leading into the site requesting it be respected by hikers and others accessing it.
https://en.wikipedia.org/wiki?curid=5643037
1,179,109
315,776
The percent crystalline content of a polymer can be estimated from the crystallization/melting peaks of the DSC graph using reference heats of fusion found in the literature. DSC can also be used to study thermal degradation of polymers using an approach such as Oxidative Onset Temperature/Time (OOT); however, the user risks contamination of the DSC cell, which can be problematic. Thermogravimetric Analysis (TGA) may be more useful for decomposition behavior determination. Impurities in polymers can be determined by examining thermograms for anomalous peaks, and plasticisers can be detected at their characteristic boiling points. In addition, examination of minor events in first heat thermal analysis data can be useful as these apparently "anomalous peaks" can in fact also be representative of process or storage thermal history of the material or polymer physical aging. Comparison of first and second heat data collected at consistent heating rates can allow the analyst to learn about both polymer processing history and material properties.
https://en.wikipedia.org/wiki?curid=97914
315,607
1,793,228
Much of the initiative in research seems to have come from below, with institutes submitting proposals for projects and funding to the State Science and Technology Commission. The commission's plans were drawn up after conferences in which scientists and directors of institutes suggested work that seemed feasible and worthwhile. The Beijing headquarters of the commission had a staff of between 500 and 1,000, not all of whom had scientific or economic backgrounds. Some of their energies were devoted to communication and coordination with other elements of the central administration, such as the State Planning Commission and the State Economic Commission. The core of the responsibility and power of the State Science and Technology Commission was in its allocation of funds for research and approval of projects. It possessed neither the manpower nor the expertise to monitor the work of the several thousand research institutes it oversaw, and of necessity it concentrated on major projects and relied on the advice of expert scientists and the regional scientific and technological commissions, which processed reports and applications for new projects. Much of its work consisted of "balancing" the competing requests for limited funds, and its decisions often were made on grounds other than scientific merit. Although China's leaders addressed the rhetoric of centralized planning to scientific research, research activities were more decentralized and more subject to pressures from powerful ministries and provincial-level governments.
https://en.wikipedia.org/wiki?curid=14246598
1,792,219
1,130,749
Baby teeth are known as primary teeth or deciduous teeth. Biologically orientated strategies for managing dental decay are considered by their proponents to have advantages for child patients receiving dental care as the techniques are less invasive and often avoid having to use local anaesthesia and drilling. They are also less destructive and potentially damaging for primary teeth. Five randomised control trials with children, on decayed primary teeth, have been carried out looking at incomplete, or no removal of decay. These have looked at how much pain and infection or repeated treatment biological techniques (including the Hall Technique) compare to other treatment techniques including complete caries removal. These "minimal intervention" approaches reduce some of the adverse consequences associated with carrying out restorative treatment: conservation of tooth structure and integrity, maintenance of maximum pulpal floor dentinal thickness, which reduces the impact on pulpal health; reduced pulp exposure, and less need for local anaesthesia if no vital dentine is being removed, which has been shown to reduce children’s reported discomfort.
https://en.wikipedia.org/wiki?curid=40701864
1,130,160
636,794
From about May 1940 70 pounds of armour plate protection was added in the form of head and back armour. Starting in September 1940, IFF equipment was installed. This weighed about 40 lb (18 kg) and could be identified by wire aerials strung between the tailplane tips and rear fuselage. Although the added weight and the aerials reduced maximum speed by about 2 mph (3 km/h), it allowed the aircraft to be identified as "friendly" on radar: lack of such equipment was a factor leading to the Battle of Barking Creek. At about the same time new VHF T/R Type 1133 radios started replacing the HF TR9 sets. The pilots enjoyed a much clearer reception, which was a big advantage with the adoption of Wing formations throughout the RAF in 1941. The new installation meant that the wire running between the aerial mast and rudder could be removed, as could the triangular "prong" on the mast.
https://en.wikipedia.org/wiki?curid=10829023
636,455
810,814
Although he came to Hamburg to work with Pauli, Rabi found Otto Stern working there with two English-speaking postdoctoral fellows, Ronald Fraser and John Bradshaw Taylor. Rabi soon made friends with them, and became interested in their molecular beam experiments, for which Stern would receive the Nobel Prize in Physics in 1943. Their research involved non-uniform magnetic fields, which were difficult to manipulate and hard to measure accurately. Rabi devised a method of using a uniform field instead, with the molecular beam at a glancing angle, so the atoms would be deflected like light through a prism. This would be easier to use, and produce more accurate results. Encouraged by Stern, and greatly assisted by Taylor, Rabi managed to get his idea to work. On Stern's advice, Rabi wrote a letter about his results to "Nature", which published it in February 1929, followed by a paper entitled "Zur Methode der Ablenkung von Molekularstrahlen" ("On the method of deflection of molecular beams") to "Zeitschrift für Physik", where it was published in April.
https://en.wikipedia.org/wiki?curid=196999
810,382