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As for other forces, the form of the Yukawa potential has a geometrical interpretation in term of the field line picture introduced by Faraday: The part results from the dilution of the field line flux in space. The force is proportional to the number of field lines crossing an elementary surface. Since the field lines are emitted isotropically from the force source and since the distance between the elementary surface and the source varies the apparent size of the surface (the solid angle) as the force also follows the  dependence. This is equivalent to the part of the potential. In addition, the exchanged mesons are unstable and have a finite lifetime. The disappearance (radioactive decay) of the mesons causes a reduction of the flux through the surface that results in the additional exponential factor formula_6 of the Yukawa potential. Massless particles such as photons are stable and thus yield only potentials. (Note however that other massless particles such as gluons or gravitons do not generally yield potentials because they interact with each other, distorting their field pattern. When this self-interaction is negligible, such as in weak-field gravity (Newtonian gravitation) or for very short distances for the strong interaction (asymptotic freedom), the potential is restored.)
https://en.wikipedia.org/wiki?curid=1324357
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Each anti-convulsant agent has a unique side-effect profile. Valproic acid can frequently cause sedation or gastrointestinal upset, which can be minimized by giving the related drug divalproex, which is available in an enteric-coated tablet. These side effects tend to disappear over time. According to studies conducted in Finland in patients with epilepsy, valproate may increase testosterone levels in teenage girls and produce polycystic ovary syndrome in women who began taking the medication before age 20. Increased testosterone can lead to polycystic ovary syndrome with irregular or absent menses, obesity, and abnormal growth of hair. Therefore, young female patients taking valproate should be monitored carefully by a physician. Excessive levels of valproate can lead to impaired liver function, and liver enzymes and serum valproate level, with a target of 50–125 µg/L, should be monitored periodically.
https://en.wikipedia.org/wiki?curid=4761393
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Using optical amplifiers, the capacity of fibers to carry information was dramatically increased with the introduction of wavelength-division multiplexing (WDM) in the early 1990s. AT&T's Bell Labs developed a WDM process in which a prism splits light into different wavelengths, which could travel through a fiber simultaneously. The peak wavelength of each beam is spaced far enough apart that the beams are distinguishable from each another, creating multiple channels within a single fiber. The earliest WDM systems had only two or four channels—AT&T, for example, deployed an oceanic 4-channel long-haul system in 1995. The erbium-doped amplifiers on which they depend, however, did not amplify signals uniformly across their spectral gain region. During signal regeneration, slight discrepancies in various frequencies introduced an intolerable level of noise, making WDM with greater than 4 channels impractical for high-capacity fiber communications.
https://en.wikipedia.org/wiki?curid=3843580
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The Confederate side of the American Civil War had a significant shortage of saltpeter. As a result, the Nitre and Mining Bureau was set up to encourage local production, including by nitre beds and by providing excrement to government nitraries. On November 13, 1862, the government advertised in the Charleston Daily Courier for 20 or 30 “able bodied Negro men” to work in the new nitre beds at Ashley Ferry, S.C. The nitre beds were large rectangles of rotted manure and straw, moistened weekly with urine, “dung water,” and liquid from privies, cesspools and drains, and turned over regularly. The National Archives published payroll records that account for more than 29,000 people compelled to such labor in the state of Virginia. The South was so desperate for saltpeter for gunpowder that one Alabama official reportedly placed a newspaper ad asking that the contents of chamber pots be saved for collection. In South Carolina, in April 1864, the Confederate government forced 31 enslaved people to work at the Ashley Ferry Nitre Works, outside Charleston.
https://en.wikipedia.org/wiki?curid=64212
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After spending most of the season behind Rosberg, Hamilton had won the previous four races, converting a 29-point deficit into a 17-point lead over his teammate. With three races left, Hamilton said he would prioritise not allowing any negative thoughts consume him and would take any opportunities presented to him: "We've just got to do our due diligence and work as hard as we can to make sure we don't have any problems." Hamilton hoped to achieve his fifth consecutive victory of the year: "A lot of the American side of my family come to the race, plus I won the first F1 GP at the circuit back in 2012 – it's a special one for me. I really enjoy going there and I'm looking forward to another great race." Rosberg aimed to improve on his best finish in Austin and lower Hamilton's points lead. He said Mercedes targeted "a big finish" to the season, declaring he would not concede defeat until the final round, and hoped to maintain the level of entertainment for the fan base.
https://en.wikipedia.org/wiki?curid=38847467
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After Kubrick's death in March 1999, Harlan and Christiane Kubrick approached Spielberg to take over the director's position. By November 1999, Spielberg was writing the screenplay based on Watson's 90-page story treatment. It was his first solo screenplay credit since "Close Encounters of the Third Kind" (1977). Spielberg remained close to Watson's treatment, but removed various sex scenes with Gigolo Joe. Pre-production was briefly halted during February 2000, because Spielberg pondered directing other projects, which were "Harry Potter and the Philosopher's Stone", "Minority Report", and "Memoirs of a Geisha". The following month Spielberg announced that "A.I." would be his next project, with "Minority Report" as a follow-up. When he decided to fast track "A.I.", Spielberg brought Chris Baker back as concept artist. Ian Watson reported that the final script was very faithful to Kubrick's vision, even the ending, which is often attributed to Spielberg, saying, "The final 20 minutes are pretty close to what I wrote for Stanley, and what Stanley wanted, faithfully filmed by Spielberg without added schmaltz."
https://en.wikipedia.org/wiki?curid=142224
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Shelley began the "Italian Lives" on 23 November 1833 and by December was working methodically: she wrote the "Lives" in the morning and read novels and memoirs in the evening. She added the revision of her novel "Lodore" (1835) and the checking of its proofs to this already busy schedule. She worked on the "Italian Lives" for two years and was probably paid £140 for each volume. By the time she began working on the "Lives", Shelley had spent 20 years studying Italian authors and had lived in Italy for five years. Her major sources for the biographies were first-person memoirs and literature by the authors, aided by scholarly works. Shelley had gained much of her knowledge of these authors in Italy when she was researching her historical novel "Valperga" (1823); the rest she obtained from her own books or those of her father, the philosopher William Godwin. She had limited access to books at this time and was thus restricted to those she owned or could borrow from friends. Shelley copied sections from some of these works in a manner that would today be termed plagiarism, but, as Mazzeo explains, because the standards of intellectual property and copyright were so different in the early 19th century, Shelley's practice was common and not considered unethical. She writes, "Mary Shelley's objectives in the "Italian Lives" were to gather what had been said by these authors and about them and to infuse the work with her own judgements on their interest and credibility."
https://en.wikipedia.org/wiki?curid=17481711
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Psychogenic disorder has been linked with basal ganglia dysfunction and dopamine deficiency observed by a decrease in neuronal density in substantia nigra in elderly patients. On an in-vivo study, the absence of dopamine in the cultures perturbed the dynamics of the subthalamic nucleus (STN) and the GABAergic neurons of the globus pallidus(GP). It is believed that the activation of the indirect pathway (striatum-GP-STN-output nuclei) increases the firing rate of GP-STN neurons resulting in an excessive inhibition of basal ganglia targets. In psychogenic disorder, the activity in the indirect pathway (inhibits movement, thoughts) predominates over that on the direct pathway (increases movement, thoughts, feelings), giving rise to an increase in the globus pallidus interior (GPi) inhibitory output, which results in decrease motor activity. Specifically, it begins on the cerebral cortex sending projections to neurons in striatum. These neurons will inhibit the external segment of the Globus Pallidus (GPe), which normally inhibits the subthalamic nucleus (STN). However, the GPe is inhibited and no longer inhibit the STN and the STN will excite the GPi which finally inhibits the thalamus and prevents from exciting to the cerebral cortex and command the spinal cord for initiation of a movement. In addition, scientists have found that the degree of slowness of movement is characterized by the decrease of F-fluorodpa uptake in the striatum and nucleus accumbens complex.
https://en.wikipedia.org/wiki?curid=22308502
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First described by William Stept and Peter Safar in 1970, "classical" or "traditional" RSI involves pre-filling the patient's lungs with a high concentration of oxygen gas; applying cricoid pressure to occlude the esophagus; administering pre-determined doses of rapid-onset sedative and neuromuscular-blocking drugs (traditionally thiopentone and succinylcholine) that induce prompt unconsciousness and paralysis; avoiding any artificial positive-pressure ventilation by mask after the patient stops breathing (to minimize insufflation of air into the stomach, which might otherwise provoke regurgitation); inserting a cuffed endotracheal tube with minimal delay; and then releasing the cricoid pressure after the cuff is inflated, with ventilation being started through the tube. There is no consensus around the precise definition of the term "modified RSI", but it is used to refer to various modifications that deviate from the classic sequence – usually to improve the patient's physiological stability during the procedure, at the expense of theoretically increasing the risk of regurgitation. Examples of such modifications include using various alternative drugs, omitting the cricoid pressure, or applying ventilation before the tube has been secured.
https://en.wikipedia.org/wiki?curid=1379570
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For sinusoidal carriers, which have no intrinsic envelope (ENV) fluctuations, the TMTF is roughly flat for AM rates from 10 to 120 Hz, but increases (i.e. threshold worsens) for higher AM rates, provided that spectral sidebands are not audible. The shape of the TMTF for sinusoidal carriers is similar for young and older people with normal audiometric thresholds, but older people tend to have higher detection thresholds overall, suggesting poorer “detection efficiency” for ENV cues in older people. Provided that the carrier is fully audible, the ability to detect AM is usually not adversely affected by cochlear hearing loss and may sometimes be better than normal, for both noise carriers and sinusoidal carriers, perhaps because loudness recruitment (an abnormally rapid growth of loudness with increasing sound level) “magnifies” the perceived amount of AM (i.e., ENV cues). Consistent with this, when the AM is clearly audible, a sound with a fixed AM depth appears to fluctuate more for an impaired ear than for a normal ear. However, the ability to detect changes in AM depth can be impaired by cochlear hearing loss. Speech that is processed with noise vocoder such that mainly envelope information is delivered in multiple spectral channels was also used in investigating envelope processing in hearing impairment. Here, hearing-impaired individuals could not make use of such envelope information as well as normal-hearing individuals, even after audibility factors were taken into account. Additional experiments suggest that age negatively affects the binaural processing of ENV at least at low audio-frequencies.
https://en.wikipedia.org/wiki?curid=56439577
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Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers. The 4th transmembrane segment of each domain is the voltage-sensing region of the channel. Following depolarization of the cell, voltage-gated sodium channels become inactivated through a change in conformation in which the 4th segments in each domain move into the pore region in response to the highly positive voltage expressed at the peak of the action potential. This effectively blocks the Na pore and prevents further influx of Na, therefore preventing further depolarization. Similarly, when the cell reaches its minimum (most negative) voltage during hyperpolarization, the 4th segments respond by moving outward, thus reopening the pore and allowing Na to flow into the cell.
https://en.wikipedia.org/wiki?curid=11352031
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Another relationship Finley discusses is the way the Ancients viewed the value of land. The ownership of a piece of land for the Ancient Greeks and Romans was not seen as a capital investment where profits could be obtained from the growing and selling of crops, but used as showpieces to enhance one's status as well as something that was inherently desirable from a traditional stand-point where economics played no part. To illustrate this, Finley turns to one of Pliny's letters where he writes that he will have to borrow money to buy more land. In the letter, Pliny does not discuss if this new purchase is an economically wise one in terms of the profits that can be derived from it. The last part of the book, Finley discusses the discrepancies between life in the urban and rural settings. He also writes about how government forces did not play a role in managing the economy and treasury in the same ways modern governments are expected to do in most Western economies.
https://en.wikipedia.org/wiki?curid=5752813
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She was awarded a Sloan Research Fellowship in 2003, becoming the second African-American woman after Kathleen Adebola Okikiolu to become a Sloan Fellow in mathematics. She won a James S. McDonnell 21st Century Scientist Grant in 2005, and won the Blackwell-Tapia Prize in 2010. In 2017, she was selected as a fellow of the Association for Women in Mathematics in the inaugural class. Jackson's work also earned her recognition by Mathematically Gifted & Black as a Black History Month 2017 Honoree. She was named a SIAM Fellow in the 2021 class of fellows, "for innovative contributions to mathematical modeling in cancer biology and for the advancement of underrepresented minorities in science". In 2021, she was awarded the University Diversity and Social Transformation Professorship at the University of Michigan, in recognition of her "extraordinary commitment to increasing opportunities for girls, women, and underrepresented minority students in STEM, through her teaching and leadership."
https://en.wikipedia.org/wiki?curid=47404029
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Navy Explosive Ordnance Disposal teams trace their history back to the first group of volunteers selected to work with the famed British UXO teams, following the initial German Blitzkrieg attacks in early 1940. In June 1941, these veterans returned to form the first class in what was originally named the Mine Recovery School. Officers and enlisted personnel entered the eleven-week school, qualifying as Mine Recovery Personnel/Second Class Divers. Between June 1941 and October 1945, nineteen classes graduated and deployed throughout the Pacific and Mediterranean theaters. Divided into Mobile Explosive Investigative Units (MEIU) they were instrumental in the clearance of explosive hazards both on land and at sea. The Korean War saw a return to action on various minesweepers ensuring the continual clearance of shipping hazards. Additionally, the now renamed Explosive Ordnance Disposal (EOD) Units took part in inland intelligence operations and interacted with ground-based units in Inchon, Wonson and throughout the United Nations Theater of operations.
https://en.wikipedia.org/wiki?curid=2533387
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According to this interpretation "factors associated with consciousness, such as meditation experience, electrocortical markers of focused attention, and psychological factors including openness and absorption, significantly correlated in predicted ways with perturbations in the double-slit interference pattern". Experiments were conducted inside a closed double-steel-walled, electromagnetically shielded chamber with a chair for a participant and a lamp. The computer (PC) inside the chamber controlled all aspects of the experiment, including announcement of the attention-toward and attention-away instructions and acquisition of interference pattern images from the double-slit device. In sum the results of these experiments are consistent with a consciousness-related interpretation of the quantum theory. Nonetheless, given the ontological and epistemological challenges presented by such an interpretation, more research will be required to confirm, systematically replicate, and extend these findings, especially to those less meditation experienced and/or less open or less absorptive. In these cases quantum interference is expected to prevail over the collapse induced by the consciousness fields of these less experienced subjects.
https://en.wikipedia.org/wiki?curid=41681462
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In November 1864, Huxley succeeded in launching a dining club, the X Club, composed of like-minded people working to advance the cause of science; not surprisingly, the club consisted of most of his closest friends. There were nine members, who decided at their first meeting that there should be no more. The members were: Huxley, John Tyndall, J. D. Hooker, John Lubbock (banker, biologist and neighbour of Darwin), Herbert Spencer (social philosopher and sub-editor of the Economist), William Spottiswoode (mathematician and the Queen's Printer), Thomas Hirst (Professor of Physics at University College London), Edward Frankland (the new Professor of Chemistry at the Royal Institution) and George Busk, zoologist and palaeontologist (formerly surgeon for HMS "Dreadnought"). All except Spencer were Fellows of the Royal Society. Tyndall was a particularly close friend; for many years they met regularly and discussed issues of the day. On more than one occasion Huxley joined Tyndall in the latter's trips into the Alps and helped with his investigations in glaciology.
https://en.wikipedia.org/wiki?curid=30038
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Alumni and faculty have invented the LED and the quantum well laser (Nick Holonyak, B.S. 1950, M.S. 1951, Ph.D. 1954), DSL (John Cioffi, B.S. 1978), JavaScript (Brendan Eich, M.S. 1986), the integrated circuit (Jack Kilby, B.S. 1947), the transistor (John Bardeen, faculty, 1951–1991), the pH meter (Arnold Beckman, B.S. 1922, M.S. 1923), MRI (Paul C. Lauterbur), the plasma screen (Donald Bitzer, B.S. 1955, M.S. 1956, Ph.D. 1960), color plasma display (Larry F. Weber, B.S. 1968 M.S. 1971 Ph.D. 1975), the training methodology called PdEI and the coin counter (James P. Liautaud, B.S. 1963), the statistical algorithm called Gibbs sampling in computer vision and the machine learning technique called random forests (Donald Geman, B.A. 1965), and are responsible for the structural design of such buildings as the Willis Tower, the John Hancock Center, and the Burj Khalifa.
https://en.wikipedia.org/wiki?curid=384695
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However, if the formation or the delivery of pebbles is slow growth timescales becomes longer than the time required for gravitationally stirring. The largest planetesimals then excite the inclinations and eccentricities of the smaller planetesimals. Their inclined orbits keep small planetesimals outside of the narrow disk of pebbles during most of their orbits, limiting their growth. The period of runaway growth is then extended and the largest objects are able to accrete a sizable fraction of the pebbles and grow into giant planet cores. As the cores grow larger some reach masses sufficient to create partial gaps in the gas disk, altering its pressure gradient and blocking the inward drift of pebbles. Accretion of pebbles is then halted and the gas envelope surrounding the core cools and collapses allowing for the rapid accretion of gas and the formation of a gas giant. Cores that do not grow massive enough to clear gaps in the pebble disk are only able to accrete small gas envelopes and instead become ice giants. The rapid growth via pebble accretion allows the cores to grow large enough to accrete massive gas envelopes forming gas giants while avoiding migrating very close to the star. In simulations cold gas giants like Jupiter and Saturn can form via pebble accretion if their initial embryos began growing beyond 20 AU. This distant formation offers a potential explanation for Jupiter's enrichment in noble gases. However, dedicated formation models indicate that it is difficult to reconcile growth via pebble accretion with the final mass and composition of the solar system ice giants Uranus and Neptune.
https://en.wikipedia.org/wiki?curid=48625218
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However, the history of Romance languages, as we know it, makes the first assumption rather problematic. While the Roman Empire lasted, its educational policies and the natural mobility of its soldiers and administrative officials probably ensured some degree of linguistic homogeneity throughout its territory. Even if there were differences between the Vulgar Latin spoken in different regions, it is doubtful whether there were any sharp boundaries between the various dialects. On the other hand, after the Empire's collapse, the population of Latin speakers was separated—almost instantaneously, by the standards of historical linguistics—into a large number of politically independent states and feudal domains whose populations were largely bound to the land. These units then interacted, merged and split in various ways over the next fifteen centuries, possibly influenced by languages external to the family (as in the so-called Balkan language area).
https://en.wikipedia.org/wiki?curid=4275231
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Soviet demands to Turkey regarding the Dardanelles in the Turkish Straits crisis and Black Sea border disputes were also a major factor in increasing tensions. In September, the Soviet side produced the Novikov telegram, sent by the Soviet ambassador to the US but commissioned and "co-authored" by Vyacheslav Molotov; it portrayed the US as being in the grip of monopoly capitalists who were building up military capability "to prepare the conditions for winning world supremacy in a new war". On 6 September 1946, James F. Byrnes delivered a speech in Germany repudiating the Morgenthau Plan (a proposal to partition and de-industrialize post-war Germany) and warning the Soviets that the US intended to maintain a military presence in Europe indefinitely. As Byrnes admitted a month later, "The nub of our program was to win the German people ... it was a battle between us and Russia over minds ..." In December, the Soviets agreed to withdraw from Iran after persistent US pressure, an early success of containment policy.
https://en.wikipedia.org/wiki?curid=325329
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On 3 March 1871, Congress passed legislation granting medical and other staff officers of the Navy "relative rank" with grades "equal to but not identical with the grades of the line." This Naval Appropriations Act went further than any previous Congressional action in transforming and enhancing the Navy Medical Department. The Chief of the Bureau of Medicine and Surgery now had the additional title "Surgeon General," with the relative rank of Commodore. At the helm of this "revitalized" organization stood the first Surgeon General, William Maxwell Wood (1809–1880), a man entering his 42nd year of a naval service as unusual and varied as could be. Wood had served aboard , one of the first steam vessels of the Navy, and designated flagship during the "expedition for the suppression of Indian hostilities on the coast of Florida" (a.k.a. the Seminole Wars). Wood served shore duty at Sackets Harbor, New York, Baltimore, Maryland, had duty as Fleet Surgeon of the Pacific Fleet, and served under Commodore John D. Sloat in California during the Mexican–American War. However fitting he may have been as the first Navy Surgeon General, he served less than two years.
https://en.wikipedia.org/wiki?curid=13250785
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Manure provides environmental benefits when properly managed. Manure that is deposited on pastures by grazing animals is an effective way to preserve soil fertility. Many nutrients are recycled in crop cultivation by collecting animal manure from barns and concentrated feeding sites, sometimes after composting. For many areas with high livestock density, manure application substantially replaces the application of synthetic fertilizers on surrounding cropland. Manure was spread as a fertilizer on about 15.8 million acres of US cropland in 2006. Manure is also spread on forage-producing land that is grazed, rather than cropped. Altogether, in 2007, manure was applied on about 22.1 million acres in the United States. Substitution of animal manure for synthetic fertilizer has important impact on energy use and greenhouse gas emissions, considering that between about 43 and 88 MJ (i.e. between about 10 and 21 Mcal) of fossil fuel energy are used per kg of N in the production of synthetic nitrogenous fertilizers.
https://en.wikipedia.org/wiki?curid=15588468
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The geographic layout of Denmark proper (not including Greenland and the Faroe Islands) has a coastline to land area ratio of 1:5.9. For comparison, the figure for the Netherlands is 1:92.1 and for the United States, 1:493.2. Denmark therefore naturally has long-standing maritime traditions, dating back to the 9th century when the Vikings had small but well-organised fleets. They were often based in a small number of villages, usually with a common defence agreement; Viking ships, usually of the "Knarr" type, were light, and therefore easy to transport from village to village over land. With time, the defence pacts gave rise to larger, more offensive fleets which the Vikings used for plundering coastal areas. In the period after the Vikings, and up to the 15th century, the fleet consisted mainly of merchant vessels. Indeed, it is said that king Valdemar Sejr had more than 1,000 ships during the conquest of Estonia in 1219. Together they carried more than 30,000 soldiers with horses and supplies.
https://en.wikipedia.org/wiki?curid=201834
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The diet of the dull-mantled antbird is composed of insects and other arthropods; recorded prey items are spiders (Araneae), cockroaches (Blattaria), beetles (Coleoptera), crickets (Gryllidae), woodlice (Oniscidea) and indeterminate insect larvae. It feeds as an individual, as a pair or in small family groups, moving close to the ground – usually not more than 10 cm above the forest floor –, every now and then jumping up to a low branch to take a look around and immediately descending again. Its prey is usually caught by gleaning, pecked up from between the leaf litter or, after a jump up or a short flutter, from vegetation. It rarely rummages through the leaf litter to search for prey; rather, it will observe its surroundings tensely, beating down its tail forcefully and slowly raising it up again, and then strike directly at something that has attracted its interest. Small prey is devoured immediately; larger animals are beaten vigorously on branches to make them easier to swallow. The species will occasionally follow army ants but it is not an obligate ant-follower like some other true antbirds or ground antbirds (Formicariidae); while it may join mixed-species feeding flocks on occasion, it usually prefers to forage on its own or with its family.
https://en.wikipedia.org/wiki?curid=12465193
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As a result of the ongoing COVID-19 pandemic the entire college ice hockey season was delayed. Despite the issues, Princeton and most of ECAC Hockey were expecting to start playing some time in November. After the teams had assembled and began practicing, however, a sizable number of Yale's players tested positive for coronavirus. On October 16, Yale raised the campus alert status from green to yellow when the 18th member of the men's ice hockey team tested positive. Less than a month later, the Ivy League, Princeton's primary conference, announced that it was cancelling all winter sports for 2020–21. Additionally the schools would not be participating in any Spring sports until the end of February. The announcement was not particularly surprising, considering that, unlike other conference, the Ivy League does not rely on revenue generated from its athletic programs.
https://en.wikipedia.org/wiki?curid=66518717
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Lymphatic filariasis is an infection of the lymph system by mosquito-borne microfilarial worms which can cause elephantiasis. Studies have demonstrated that transmission of the infection can be broken when a single dose of combined oral medicines is consistently maintained annually for approximately seven years. The strategy for eliminating transmission of lymphatic filariasis is mass distribution of medicines that kill the microfilariae and stop transmission of the parasite by mosquitoes in endemic communities. In sub-Saharan Africa, albendazole is being used with ivermectin to treat the disease, whereas elsewhere in the world albendazole is used with diethylcarbamazine. Using a combination of treatments better reduces the number of microfilariae in blood. Avoiding mosquito bites, such as by using insecticide-treated mosquito bed nets, also reduces the transmission of lymphatic filariasis. In the Americas, 95% of the burden of lymphatic filariasis is on the island of Hispaniola (comprising Haiti and the Dominican Republic). An elimination effort to address this is currently under way alongside the malaria effort described above; both countries intend to eliminate the disease by 2020.
https://en.wikipedia.org/wiki?curid=14499186
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The technology uses a high-powered, hand-held, computer-controlled flashgun to deliver an intense, visible, broad-spectrum pulse of light, generally in the visible spectral range of 400 to 1200 nm. Various cutoff filters are commonly used to selectively filter out shorter wavelengths, especially potentially damaging ultra violet light. The resulting light has a spectral range that targets specific structures and chromophores (e.g. melanin in hair, or oxyhemoglobin in blood vessels) that are heated to destruction and reabsorbed by the body. IPL shares some similarities with laser treatments, in that they both use light to heat and destroy their targets. But unlike lasers that use a single wavelength (color) of light which typically matches only one chromophore and hence only treats one condition, IPL uses a broad spectrum that when used with interchangeable filters, allowing it to be used against several conditions. This can be achieved when the IPL technician selects the appropriate filter that matches a specific chromophore.
https://en.wikipedia.org/wiki?curid=298541
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In a phase space, every degree of freedom or parameter of the system is represented as an axis of a multidimensional space; a one-dimensional system is called a phase line, while a two-dimensional system is called a phase plane. For every possible state of the system or allowed combination of values of the system's parameters, a point is included in the multidimensional space. The system's evolving state over time traces a path (a phase-space trajectory for the system) through the high-dimensional space. The phase-space trajectory represents the set of states compatible with starting from one particular initial condition, located in the full phase space that represents the set of states compatible with starting from "any" initial condition. As a whole, the phase diagram represents all that the system can be, and its shape can easily elucidate qualities of the system that might not be obvious otherwise. A phase space may contain a great number of dimensions. For instance, a gas containing many molecules may require a separate dimension for each particle's "x", "y" and "z" positions and momenta (6 dimensions for an idealized monatomic gas), and for more complex molecular systems additional dimensions are required to describe vibrational modes of the molecular bonds, as well as spin around 3 axes. Phase spaces are easier to use when analyzing the behavior of mechanical systems restricted to motion around and along various axes of rotation or translation e.g. in robotics, like analyzing the range of motion of a robotic arm or determining the optimal path to achieve a particular position/momentum result.
https://en.wikipedia.org/wiki?curid=191101
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Due to non-compaction cardiomyopathy being a relatively new disease, its impact on human life expectancy is not very well understood. In a 2005 study that documented the long-term follow-up of 34 patients with NCC, 35% had died at the age of 42 +/- 40 months, with a further 12% having to undergo a heart transplant due to heart failure. However, this study was based upon symptomatic patients referred to a tertiary-care center, and so were experiencing more severe forms of NCC than might be found typically in the population. Sedaghat-Hamedani et al. also showed the clinical course of symptomatic LVNC can be severe. In this study cardiovascular events were significantly more frequent in LVNC patients compared with an age-matched group of patients with non-ischaemic dilated cardiomyopathy (DCM). As NCC is a genetic disease, immediate family members are being tested as a precaution, which is turning up more supposedly healthy people with NCC who are asymptomatic. The long-term prognosis for these people is currently unknown.
https://en.wikipedia.org/wiki?curid=11752092
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The original backronym used for the initial mission concept, "ATLAST", was a pun referring to the time taken to decide on a successor for HST. ATLAST itself had three different proposed architectures – an monolithic mirror telescope, a segmented mirror telescope, and a segmented mirror telescope. The current LUVOIR-B architecture adopts JWST design heritage, essentially being an incrementally larger variant of the JWST, which has a 6.5 m segmented main mirror. Running on solar power, it would use an internal coronagraph or an external occulter which can characterize the atmosphere and surface of an Earth-sized exoplanet in the habitable zone of long-lived stars at distances up to , including its rotation rate, climate, and habitability. The telescope would also allow researchers to glean information on the nature of the dominant surface features, changes in cloud cover and climate, and, potentially, seasonal variations in surface vegetation. LUVOIR-B was designed to launch on a heavy-lift rocket with an industry-standard diameter launch fairing. Lifetime cost estimates range from $12 billion to $18 billion.
https://en.wikipedia.org/wiki?curid=52350237
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Another aspect of analysis is the balance between current intelligence and long-term estimates. For many years, the culture of the intelligence community, in particular that of the CIA, favored the estimates. However, it is in long-term analysis of familiar subjects and broad trends where secret information tends to be less critical and government analysts are, for the most part, no better and often not as good as their counterparts in academia and the private sector. Also, many estimates are likely to be less relevant to busy policy-makers, who must focus on the immediate. To the extent long-term estimates are produced, it is important that they be concise, written by individuals, and that sources justifying conclusions be shown as they would in any academic work. If the project is a group effort, differences among participants need to be sharpened and acknowledged. While it is valuable to point out consensus, it is more important that areas of dispute be highlighted than that all agencies be pressured to reach a conclusion that may represent a lowest common denominator.
https://en.wikipedia.org/wiki?curid=13979889
1,405,988
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Russia started building new icebreakers, Project 22220, in 2013. In June 2008 the head of the state nuclear corporation Rosatom, Sergei Kiriyenko, said "It is important to not only use the existing fleet of icebreakers, but also to build new ships, and the first nuclear icebreaker of a new generation will be built by 2015. This should be an icebreaker capable of moving in rivers and seas", he said. He went on saying that the Iceberg Design Bureau in St. Petersburg would prepare the design of the icebreaker by 2009. According to the BBC the LK-60 (ЛК60Я) will be the biggest nuclear-powered icebreaker that was ever built. Sergei Kiriyenko, head of the state nuclear corporation Rosatom ordered the responsible operator Atomflot to build up to three nuclear icebreakers until 2016. The construction of a nuclear-powered icebreaker takes eight years, the fuel endurance is about 25 years and the reactor can be refueled. According to the Transport Ministry, Russia needs six new icebreakers in the future. In October 2020, the first Project 22220 icebreaker, a new vessel named "Arktika", completed sea trials and began operations in Arctic waters. The second ("Sibir") began sea trials in November 2021.
https://en.wikipedia.org/wiki?curid=483169
980,604
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The history of the development of GM crop and GM food regulations in the EU has been challenged to develop a policy environment that is (a) efficient, (b) predicable, (c) accountable, (d) durable or (e) inter- jurisdictionally aligned. However, although the European Union has had relatively strict regulations regarding the genetically modified food, Europe is now allowing newer versions of modified maize and other agricultural produce. Also, the level of GMO acceptance in the European Union varies across its countries with Spain and Portugal being more permissive of GMOs than France and the Nordic population. One notable exception however is Sweden. In this country, the government has declared that the GMO definition (according to Directive 2001/18/EC) stipulates that foreign DNA needs to be present in an organism for it to qualify as a genetically modified organisms. Organisms that have the foreign DNA removed (for example via selective breeding) therefore do not qualify as GMO's, even if gene editing has been used to make the organism.
https://en.wikipedia.org/wiki?curid=31540040
1,303,854
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Listening to music and general audio is commonly not a task directed activity. People enjoy music for various poorly understood reasons, which are commonly referred to the emotional effect of music due to creation of expectations and their realization or violation. Animals attend to signs of danger in sounds, which could be either specific or general notions of surprising and unexpected change. Generally, this creates a situation where computer audition can not rely solely on detection of specific features or sound properties and has to come up with general methods of adapting to changing auditory environment and monitoring its structure. This consists of analysis of larger repetition and self-similarity structures in audio to detect innovation, as well as ability to predict local feature dynamics.
https://en.wikipedia.org/wiki?curid=9536113
1,637,968
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In the lower panel of the figure, a collimator has been added (blue bars). This may be a sheet of lead or other material opaque to the incoming radiation with many tiny holes bored through it or in the case of neutrons it can be a sandwich arrangement (which can be up to several feet long - see ENGIN-X) with many layers alternating between neutron absorbing material (e.g. gadolinium) with neutron transmitting material. This can be something simple e.g. air. or if mechanical strength is needed then aluminium may be used. If this forms part of a rotating assembly, the sandwich may be curved. This allows energy selection in addition to collimation - the curvature of the collimator and its rotation will present a straight path only to one energy of neutrons. Only rays that are travelling nearly parallel to the holes will pass through them—any others will be absorbed by hitting the plate surface or the side of a hole. This ensures that rays are recorded in their proper place on the plate, producing a clear image.
https://en.wikipedia.org/wiki?curid=1165029
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When attacking "Luftwaffe" bombers, it was discovered that the Hurricane's fuel tanks were vulnerable to defensive machine gun fire. The greatest hazard was with the unprotected gravity-feed fuel tank in front of the cockpit which could rupture when hit, allowing a jet of flame to penetrate the cockpit through the instrument panel, causing serious burn injuries to the pilot. The wooden and fabric rear fuselage was also far more likely to catch fire than the metal fuselages of its contemporaries. This issue was of such concern to Air Vice Marshal Hugh Dowding that he had Hawker retrofit the fuselage tanks of Hurricanes with a fire-resistant material called "Linatex" as a matter of priority. The wing tanks had already been fitted with a covering of this sealant, but the fuselage tank was considered to be too small a target. Hurricanes were soon being modified at the rate of 75 per month. In one month of combat, 10 July 1940 to 11 August, defensive fire from bombers hit 25 Hurricanes and 25 Spitfires; as a result 11 Hurricanes were shot down compared with two Spitfires.
https://en.wikipedia.org/wiki?curid=10829023
636,460
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In 1961 ATIC became the Foreign Technology Division (FTD) which was reassigned to Air Force Systems Command (AFSC), and FTD intelligence estimates were subsequently provided to the National Security Council through the 1962 United States Intelligence Board (cf. the CIA's Board of National Estimates). FTD's additional location at the Tonopah Test Range Airport conducted test and evaluation of captured Soviet fighter aircraft (AFSC recruited its pilots from the Edwards AFB Air Force Test Center). The aircraft of the 1966 Iraqi Air Force MiG-21 defection was transferred to Nevada within a month of the flight, and the 1968 US Air Force and Navy "HAVE DOUGHNUT" project flew the aircraft at Area 51 for simulated air combat training (renamed "HAVE DRILL" and transferred to the Tonopah TTR ). U.S. casualties flying foreign aircraft included those in the 1979 Tonopah MiG-17 crash during training versus a Northrop F-5 and the 1984 Little Skull Mountain MiG-23 crash which killed a USAF general.
https://en.wikipedia.org/wiki?curid=38616763
1,109,946
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John Cade was born in Murtoa, in the Wimmera region of Victoria, Australia. John's father David was Murtoa's general practitioner. Ellen, John's mother, and younger brothers David and Frank completed the family. When John was a small boy, his father left for World War I and served in Gallipoli and France. On return from the war, his father suffered from 'war-weariness' and had difficulty in continuing in general practice. Therefore, his father sold the practice and accepted a position with the Mental Hygiene Department. Over the next 25 years, Dr Cade Sr became medical superintendent at several Victorian mental hospitals, namely Sunbury, Beechworth and Mont Park. John and his brothers spent many of their younger years living within the grounds of these institutions, which had a great bearing on John's later deep understanding of the needs of the mentally ill. John was educated at Scotch College, Melbourne, matriculating in 1928. He then studied medicine at the University of Melbourne, graduating at the age of 21 years with honours in all subjects. He became a House Officer at St Vincent's Hospital and then Royal Children's Hospital before becoming severely ill with bilateral pneumococcal pneumonia. While he was convalescing, John fell in love with one of his nurses, Jean. They married in 1937.
https://en.wikipedia.org/wiki?curid=16285
1,155,095
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Holland graduated from Central High, Omaha, Nebraska, in 1938 and from the University of Nebraska at Omaha (then "Municipal University of Omaha") in 1942. He received his B.A. in Psychology (and also studied French and math). Holland joined the army after graduating from college, becoming engaged in the events of World War II. He stayed with the army as a private until 1946, working as "a classification interviewer, test proctor, paralegal clerk, laborer, squadron clerk, psychological assistant, and Wechsler test administrator [... this experience] led to his belief that many people exemplify common psychological types, although his training had fostered the belief that people are infinitely complex. He was also able to work with and get training from social workers, psychologists, and physicians—experiences that stimulated his desire to become a psychologist." After leaving the army, he entered a doctoral program in psychology at the University of Minnesota, receiving a master's degree in 1947 and a Ph.D. in 1952.
https://en.wikipedia.org/wiki?curid=3012288
1,195,906
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PBN procedures also reduced oceanic separation standards laterally and longitudinally from 100 nautical miles to 30 nmi. PBN improved lateral separation standards for approaches at airports with closely spaced parallel runways from 4,300 feet to 3,600 feet in 2013, and an Equivalent Lateral Spacing Operations standard enabled through PBN gives extra flexibility at airports for additional departures. A rule change in 2015 allowed pilots to use a PBN approach procedure to take a shorter path to the runway more frequently. Aircraft can safely and efficiently land at certain airports with parallel runways without receiving directions from air traffic controllers monitoring them on radar. The FAA implemented a national standard in 2016 for that capability, which is known as Established on RNP.
https://en.wikipedia.org/wiki?curid=12942905
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At each point of a superconducting electronic circuit (a network of electrical elements), the condensate wave function describing charge flow is well-defined by some complex probability amplitude. In typical conductor electrical circuits, this same description is true for individual charge carriers except that the various wave functions are averaged in macroscopic analysis, making it impossible to observe quantum effects. The condensate wave function becomes useful in allowing design and measurement of macroscopic quantum effects. Similar to the discrete atomic energy levels in the Bohr model, only discrete numbers of magnetic flux quanta can penetrate a superconducting loop. In both cases, quantization results from complex amplitude continuity. Differing from microscopic implementations of quantum computers (such as atoms or photons), parameters of superconducting circuits are designed by setting (classical) values to the electrical elements composing them such as by adjusting capacitance or inductance.
https://en.wikipedia.org/wiki?curid=1730328
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In the mid-1930s Polish small-arms designer Wawrzyniec Lewandowski was tasked with developing a flexible aircraft-mounted machine gun based on the Browning wz.1928. This resulted in the wz. 1937. Changes included increasing the weapon's rate of fire to 1,100 rounds/min, eliminating the butt stock, adding a spade-type grip to the rear of the receiver, moving the main drive spring under the barrel and, most importantly, changing the feed system. Sustained fire was practically impossible with the standard 20-round box magazine, so a new feed mechanism was developed that was added to the receiver as a module. It contains a spring-loaded, bolt-actuated lever that would feed a round from a 91-round pan magazine located above the receiver and force the round into the feed path during unlocking. The machine gun was accepted in 1937 and ordered by the Polish Air Force as the "karabin maszynowy obserwatora wz. 1937" ("observers machine gun model 1937"). Eventually 339 machine guns were acquired and used as armament in the PZL.37 Łoś medium bomber and the LWS-3 Mewa reconnaissance aircraft.
https://en.wikipedia.org/wiki?curid=378838
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Treatment options for distal radius fractures include nonoperative management, external fixation, and internal fixation. Indications for each depend on a variety of factors such as the patient's age, initial fracture displacement, and metaphyseal and articular alignment, with the ultimate goal to maximize strength and function in the affected upper extremity. Surgeons use these factors combined with radiologic imaging to predict fracture instability, and functional outcome to help decide which approach would be most appropriate. Treatment is often directed to restore normal anatomy to avoid the possibility of malunion, which may cause decreased strength in the hand and wrist. The decision to pursue a specific type of management varies greatly by geography, physician specialty (hand surgeons vs. orthopedic surgeons), and advancements in new technology such as the volar locking plating system.
https://en.wikipedia.org/wiki?curid=1272984
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The earliest recorded beginnings of geometry can be traced to ancient Mesopotamia and Egypt in the 2nd millennium BC. Early geometry was a collection of empirically discovered principles concerning lengths, angles, areas, and volumes, which were developed to meet some practical need in surveying, construction, astronomy, and various crafts. The earliest known texts on geometry are the Egyptian "Rhind Papyrus" (2000–1800 BC) and "Moscow Papyrus" (c. 1890 BC), and the Babylonian clay tablets, such as Plimpton 322 (1900 BC). For example, the Moscow Papyrus gives a formula for calculating the volume of a truncated pyramid, or frustum. Later clay tablets (350–50 BC) demonstrate that Babylonian astronomers implemented trapezoid procedures for computing Jupiter's position and motion within time-velocity space. These geometric procedures anticipated the Oxford Calculators, including the mean speed theorem, by 14 centuries. South of Egypt the ancient Nubians established a system of geometry including early versions of sun clocks.
https://en.wikipedia.org/wiki?curid=18973446
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Occupational therapy—often abbreviated OT—is the "use of productive or creative activity in the treatment or rehabilitation of physically, cognitively, or emotionally disabled people." Most commonly, occupational therapists work with people with disabilities to enable them to maximize their skills and abilities. Occupational therapy practitioners are skilled professionals whose education includes the study of human growth and development with specific emphasis on the physical, emotional, psychological, sociocultural, cognitive and environmental components of illness and injury. They commonly work alongside clinical psychologists in settings such as inpatient and outpatient mental health, pain management clinics, eating disorder clinics, and child development services. OT's use support groups, individual counseling sessions, and activity-based approaches to address psychiatric symptoms and maximize functioning in life activities.
https://en.wikipedia.org/wiki?curid=492271
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The data collected on Jupiter and its moons was stored in the spacecraft's onboard tape recorder, and transmitted back to Earth during the long apoapsis portion of the probe's orbit using the low-gain antenna. At the same time, measurements were made of Jupiter's magnetosphere and transmitted back to Earth. The reduction in available bandwidth reduced the total amount of data transmitted throughout the mission, but William J. O'Neil, "Galileo" project manager from 1992 to 1997, expressed confidence that 70 percent of "Galileo" science goals could still be met. The decision to use magnetic tape for storage was a conservative one, taken in the late 1970s when the use of tape was common. But conservatism was not restricted to engineers; a 1980 suggestion that the results of "Galileo" could be distributed electronically instead of on paper was regarded as ridiculous by geologists, on the grounds that storage would be prohibitively expensive; some of them thought that taking measurements on a computer involved putting a wooden ruler up to the screen.
https://en.wikipedia.org/wiki?curid=13077
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To follow up this study, Roediger and McDermott conducted a second experiment that allowed better experimental control. This time they created extra lists similar to those used by Deese, except the new lists had 15 items instead of 12 and the design was manipulated in a few minor ways. The major difference in this second experiment was the inclusion of a 'remember-know' judgement task. This task is applied to a recognition test in order to determine whether subjects recognise an item based on their memory, or based on familiarity. Subjects are first asked if an item is one they have seen before (old) or one that they have not (new), then for items that they have classified as 'old', subjects are asked to judge if they can mentally relive the experience of the item being presented (remember), or if they are confident that it occurred without having a memory for the event (know). Roediger and McDermott predicted that subjects were recalling an absent word because of a high sense of familiarity induced through the presented lists, and as such they would predominantly judge 'old' critical lures as being 'known' rather than 'remembered'. This prediction was not supported. The second experiment showed an increase in recall of the absent critical lures (to a level marginally significantly greater than actually presented words), which was paired with 72% of recognised critical lures being judged as 'remembered'. These results show clear evidence of subjects 'remembering' events that never occurred.
https://en.wikipedia.org/wiki?curid=33034691
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Vernon R. Alden Library serves the Athens campus as the central library facility. There are several, smaller libraries within other academic buildings that serve various departments and programs, as well as smaller, specialized specific collection libraries within the Vernon R. Alden Library building. University librarians work for different departments and all are experts in some discipline of their own choosing. This gives students access to produce their own original research and assistance when needed. Many Ohio University courses require students to utilize the library and librarians to produce their own original writing and many go on to publish their works with the help of the librarians. There is a library annex building which is located on Columbus Road in Athens, which houses preservation and other offices. Also housed within Alden Library, The Ohio University Press is Ohio University's publishing company, located on the first floor. Each regional campus has their own library and printed text collections complete with their own staff and various librarians. The collection of OHIO's library contains over 2.3 million units of microfilm material, 13,500 periodical subscriptions and more than 4 million printed volumes, making it one of the 100 largest libraries in the United States. Alden Library was the first in the world to generate an electronic library record in 1971. The university maintains a complex system of archives in its libraries. The Robert E. and Jean R. Mahn Center for Archives and Special Collections maintains and displays rare books and collections, including a 14th-century Gutenberg Bible. Laptops and other accessories are available through technology services at the reference desk. Outside Alden Library and directly behind Cutler Hall is Wolfe Garden, a small enclave in the shape of the State of Ohio, which features native Ohio trees and plants.
https://en.wikipedia.org/wiki?curid=483329
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In 1880, Bell received the Volta Prize with a purse of 50,000 French francs (approximately US$ in today's dollars) for the invention of the telephone from the French government. Among the luminaries who judged were Victor Hugo and Alexandre Dumas, "fils". The Volta Prize was conceived by Napoleon III in 1852, and named in honor of Alessandro Volta, with Bell becoming the second recipient of the grand prize in its history. Since Bell was becoming increasingly affluent, he used his prize money to create endowment funds (the 'Volta Fund') and institutions in and around the United States capital of Washington, D.C.. These included the prestigious" 'Volta Laboratory Association' "(1880), also known as the" Volta Laboratory "and as the" 'Alexander Graham Bell Laboratory', "and which eventually led to the Volta Bureau (1887) as a center for studies on deafness which is still in operation in Georgetown, Washington, D.C. The Volta Laboratory became an experimental facility devoted to scientific discovery, and the very next year it improved Edison's phonograph by substituting wax for tinfoil as the recording medium and incising the recording rather than indenting it, key upgrades that Edison himself later adopted. The laboratory was also the site where he and his associate invented his "proudest achievement", "the photophone", the "optical telephone" which presaged fibre optical telecommunications while the Volta Bureau would later evolve into the Alexander Graham Bell Association for the Deaf and Hard of Hearing (the AG Bell), a leading center for the research and pedagogy of deafness.
https://en.wikipedia.org/wiki?curid=852
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In the current economy, fossil fuels account for most competitive markets between big businesses. This leads to a constant fluctuation in economic prices being considerably high or low depending on supply and demand. Unlike fossil fuels which are non-renewable, rivers, lakes, and ocean water are an infinite resource. Dams are a product of the water-power engine and provide consistent energy to nearby populated areas. Murray 1 and 2 Hydro Electric Power Stations and the Tumut 3 Hydroelectric Power Station in Australia is responsible for generating between 550 megawatts and 1,800 megawatts of electricity. The water powered turbines used in these dams need little maintenance, are easily upgradable with modern technology, and have a lifespan of 50–100 years.
https://en.wikipedia.org/wiki?curid=19949953
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The Second generation of Ketris would be developed at Intel as an architecture for the telecommunications industry to support the build out of IP base telecom services and in particular the LTE (Long Term Evolution) Cellular Network build-out. PICMG followed with this larger and more feature-rich AdvancedTCA specification, targeting the telecom industry's need for a high availability and dense computing platform with extended product life (10+ years). While AdvancedTCA system and boards typically sell for higher prices than blade servers, the operating cost (manpower to manage and maintain) are dramatically lower, where operating cost often dwarf the acquisition cost for traditional servers. AdvancedTCA promote them for telecommunications customers, however in the real world implementation in Internet Data Centers where thermal as well as other maintenance and operating cost had become prohibitively expensive, this blade server architecture with remote automated provisioning, health and performance monitoring and management would be a significantly less expensive operating cost.
https://en.wikipedia.org/wiki?curid=881423
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However, the model is incomplete as it neglects retardation effects due to the finite cavity photon decay rate formula_13. The force follows the motion of the mirror only with some time delay, which leads to effects like friction. For example, assume the equilibrium position sits somewhere on the rising slope of the resonance. In thermal equilibrium, there will be oscillations around this position that do not follow the shape of the resonance because of retardation. The consequence of this delayed radiation force during one cycle of oscillation is that work is performed, in this particular case it is negative,formula_14, i.e. the radiation force extracts mechanical energy (there is extra, light-induced damping). This can be used to cool down the mechanical motion and is referred to as optical or optomechanical cooling. It is important for reaching the quantum regime of the mechanical oscillator where thermal noise effects on the device become negligible. Similarly, if the equilibrium position sits on the falling slope of the cavity resonance, the work is positive and the mechanical motion is amplified. In this case the extra, light-induced damping is negative and leads to amplification of the mechanical motion (heating). Radiation-induced damping of this kind has first been observed in pioneering experiments by Braginsky and coworkers in 1970.
https://en.wikipedia.org/wiki?curid=49916168
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Following Saddam Hussein's threats to light Kuwait's oil wells on fire in response to any physical challenge to Iraqi control of the oil assets, Sagan together with his "TTAPS" colleagues and Paul Crutzen, warned in January 1991 in "The Baltimore Sun" and "Wilmington Morning Star" newspapers that if the fires were left to burn over a period of several months, enough smoke from the 600 or so 1991 Kuwaiti oil fires "might get so high as to disrupt agriculture in much of South Asia ..." and that this possibility should "affect the war plans"; these claims were also the subject of a televised debate between Sagan and physicist Fred Singer on January 22, aired on the ABC News program "Nightline". In the televised debate, Sagan argued that the effects of the smoke would be similar to the effects of a nuclear winter, with Singer arguing to the contrary. After the debate, the fires burnt for many months before extinguishing efforts were complete. The results of the smoke did not produce continental-sized cooling. Sagan later conceded in "The Demon-Haunted World" that the prediction did not turn out to be correct: "it "was" pitch black at noon and temperatures dropped 4–6 °C over the Persian Gulf, but not much smoke reached stratospheric altitudes and Asia was spared".
https://en.wikipedia.org/wiki?curid=6824
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Several critics wrote that "Portal 2" excels in teaching the player to solve puzzles; in a review for the "New York Times", Seth Schiesel wrote, "Somewhere out there an innovative, dynamic high school physics teacher will use "Portal 2" as the linchpin of an entire series of lessons and will immediately become the most important science teacher those lucky students have ever had." Mathematics and science teachers wrote e-mails to Valve to tell them how they had included "Portal" in their classroom lessons as part of a project to promote the "gamification of learning". "Portal" developers Joshua Weier and Yasser Malaika led a team within Valve to explore ways of using "Portal 2" for education. This led to the development of "Puzzle Maker", a level editor for "Portal 2" players, built from the professional tools used to develop the game. Weier and Malaika did not want to design curricula themselves, but wanted to provide educators with tools for creating lesson plans. Hammer, the only tool freely available before the release of the built-in level editor in 2012, was difficult for educators to learn and understand. To address this, Valve gave "Puzzle Maker" an easy-to-learn interface and the ability to share puzzles and lesson plans. The tools were developed with a mathematics teacher and her students. This formed the basis of a new "Steam for Schools" initiative launched in June 2012, under which educators could acquire "Portal 2" and the Puzzle Maker software free of charge for classroom use through its "Teach with Portals" program. In November 2012, Valve estimated that over 2,500 educators were using the "Teach with Portals" software within their lesson plans.
https://en.wikipedia.org/wiki?curid=15888290
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In 2018, Alnylam Pharmaceuticals became the first company to have a siRNA therapy approved by the FDA. Onpattro (patisiran) was approved for the treatment of polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. hATTR is a rare, progressively debilitating condition. During hATTR amyloidosis, misfolded transthyretin (TTR) protein is deposited in the extracellular space. Under typical folding conditions, TTR tetramers are made up of four monomers. Hereditary ATTR amyloidosis is caused by a fault or mutation in the transthyretin (TTR) gene which is inherited. Changing just one amino-acid changes the tetrameric transthyretin proteins, resulting in unstable tetrameric transthyretin protein that aggregates in monomers and forms insoluble extracellular amyloid deposits. Amyloid buildup in various organ systems causes cardiomyopathy, polyneuropathy, gastrointestinal dysfunction. It affects 50,000 people worldwide. To deliver the drug directly to the liver, siRNA is encased in a lipid nanoparticle. The siRNA molecule halts the production of amyloid proteins by interfering with the RNA production of abnormal TTR proteins. This prevents the accumulation of these proteins in different organs of the body and helps the patients manage this disease.
https://en.wikipedia.org/wiki?curid=584617
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The Biodiversity Institute of Ontario is the world's first centre for high-volume DNA barcoding–the rapid identification of millions of species. It is anticipated faculty will enter over 500,000 barcode analyses per year. The university's School of Engineering had an approximately $50 million expansion between 2009 and 2011 in the form of new construction and renovations. This is in response to new mechanical, biomedical and computer engineering programs, increased enrolment in undergraduate and graduate programs and expanded research in sustainability-related areas. Alexander Hall is an environmental teaching and research centre. The Animal Cancer Centre is Canada's first institute for comparative cancer investigation. It includes a linear accelerator offering animal radiation treatment available.
https://en.wikipedia.org/wiki?curid=9181362
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However, as more studies were conducted, more variability was found in ANS responses to discrete emotion inductions, not only among individuals but also over time in the same individuals, and greatly between social groups. Some of these differences can be attributed to variables like induction technique, context of the study, or classification of stimuli, which can alter a perceived scenario or emotional response. However it was also found that features of the participant could also alter ANS responses. Factors such as basal level of arousal at the time of experimentation or between test recovery, learned or conditioned responses to certain stimuli, range and maximal level of effect of ANS action, and individual attentiveness can all alter physiological responses in a lab setting. Even supposedly discrete emotional states fail to show specificity. For example, some emotional typologists consider fear to have subtypes, which might involve fleeing or freezing, both of which can have distinct physiological patterns and potentially distinct neural circuitry. As such no definitive correlation can be drawn linking specific autonomic patterns to discrete emotions, causing emotion theorists to rethink classical definitions of emotions.
https://en.wikipedia.org/wiki?curid=23732
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DSCE is located in Bangalore, Karnataka. It is a sector of Dayananda Sagar Institutions. The institute is named after its founder, Shri R Dayananda Sagar, best known for his role in setting up the Mahatma Gandhi Vidhya Peetha Education Trust in 1960, Sagar also played an important role in the education sector of emerging India. It is an autonomous institute affiliated to Visvesvaraya Technological University. DSCE has been securing maximum marks under Visvesvaraya Technological University for five years, continuing the trend of securing 54 university ranks, highest by any college in Karnataka. In 2015, the college was granted autonomy. It is an certified institute, approved by AICTE and the University Grants Commission, and accredited by the National Assessment and Accreditation Council. It is ranked as one of the top engineering colleges in Karnataka. It is run by the Mahatma Gandhi Vidya Peetha Trust. The trust manages 28 institutions in the name of Dayananda Sagar Institutions and multi-speciality hospitals in the name of Sagar Hospitals The institute offers a wide choice of engineering branches, with 15 undergraduate and 13 postgraduate courses. Some of the Engineering branches are accredited by the National Board of Accreditation. The institute has received a National Mission Project from the Department of Scientific and Industrial Research. It has 21 research centres in different branches of engineering which are recognised by Visvesvaraya Technological University..
https://en.wikipedia.org/wiki?curid=5432514
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The boom years were 1836 and 1845–47, when Parliament authorized 8,000 miles of lines at a projected cost of £200 million, which was about the same value as the country's annual Gross Domestic Product (GDP) at that time. A new railway needed an Act of Parliament, which typically cost over £200,000 (about $1 million) to obtain, but opposition could effectively prevent its construction. The canal companies, unable or unwilling to upgrade their facilities to compete with railways, used political power to try to stop them. The railways responded by purchasing about a quarter of the canal system, in part to obtain the right of way, and in part to buy off critics. Once an Act was obtained, there was little government regulation. The railways largely had exclusive territory, but given the compact size of Britain, this meant that two or more competing lines could connect major cities.
https://en.wikipedia.org/wiki?curid=8076215
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A heat-conductive surface, such as porcelain or metal, is heated to a temperature that will induce a nociceptive response in an animal subject – normally 50–56 °C. The subject is then placed onto the surface and prevented from leaving the platform by blockades. The latency to pain-reflex behavior is measured. One complication of this assay is its unsuitability for repeated testing. Animals that have been subjected to the hot-plate test in the past display a behavioral tolerance phenomenon, which is characterized by decreased latencies and reduced sensitivities to antinociceptive agents. Another complication of the hot-plate test is determining what constitutes a behavioral pain response; is it the lifting/licking of paws, vocalization, attempting to climb out of the cylinder, etc. Also, delivering the heat stimulus in a controlled fashion presents difficulties due to each section having varying temperatures based upon surface area exposure and whether the animal is moving or not.
https://en.wikipedia.org/wiki?curid=31479566
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The spores are roughly spherical, thick-walled, 3–6 µm in diameter (although some specimens collected in the US range from 7.2 to 9.5 µm), and are covered with minute spines or warts. The use of scanning electron microscopy has revealed that these ornamentations on the spores are typically 0.95 µm long. Spore ultrastructure is distinctive among "Calvatia" species, and has been used to help verify taxonomic groupings and confirm the status of species within the genus. The capillitia (coarse, thick-walled hyphae in the gleba) are septate, with branches that are narrowed towards the tips; they are 3–8 µm in diameter. When grown in pure culture in the laboratory, "C. sculpta" is, under certain conditions, able to grow structures called "mycelial strands". These are linear aggregates of hyphae whereby older "leading" hyphae become enclosed by coiled layers of newer "tendril" hyphae. Mycelial strands provide a conduit for transporting water and nutrients across non-nutrient material, allowing the fungus to reach new sources of food. They are also implicated in the formation of fruit bodies and sclerotia. The mycelia of "C. sculpta" can be induced to form mycelial strands when there is a permeable physical barrier between it and the agar substrate. The wide hyphae in the center of the mycelial strands contain protein-dense structures on their cell walls that are shaped like a torus. Their function is unknown.
https://en.wikipedia.org/wiki?curid=23772391
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The "Critique of Pure Reason" has exerted an enduring influence on Western philosophy. The constructive aspect of the work, Kant's attempt to ground the conditions for the possibility of objects in the conditions of experience, helped bring about the development of German idealism. The work also influenced Young Hegelians such as Bruno Bauer, Ludwig Feuerbach and Karl Marx, and also, Friedrich Nietzsche, whose philosophy has been seen as a form of "radical Kantianism" by Howard Caygill. Other interpretations of the "Critique" by philosophers and historians of philosophy have stressed different aspects of the work. The late 19th-century neo-Kantians Hermann Cohen and Heinrich Rickert focused on its philosophical justification of science, Martin Heidegger and Heinz Heimsoeth on aspects of ontology, and Peter Strawson on the limits of reason within the boundaries of sensory experience. Hannah Arendt and Jean-François Lyotard dealt with its work of orientation of a limited understanding in the field of world history. According to Homer W. Smith,
https://en.wikipedia.org/wiki?curid=347543
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While the spectral-based methods presented in the previous section are computationally attractive, they do not always yield sufficient accuracy. In particular, for the cases when we have highly correlated signals, the performance of spectral-based methods may be insufficient. An alternative is to more fully exploit the underlying data model, leading to so-called parametric array processing methods. The cost of using such methods to increase the efficiency is that the algorithms typically require a multidimensional search to find the estimates. The most common used model based approach in signal processing is the maximum likelihood (ML) technique. This method requires a statistical framework for the data generation process. When applying the ML technique to the array processing problem, two main methods have been considered depending on the signal data model assumption. According to the Stochastic ML, the signals are modeled as Gaussian random processes. On the other hand, in the Deterministic ML the signals are considered as unknown, deterministic quantities that need to be estimated in conjunction with the direction of arrival.
https://en.wikipedia.org/wiki?curid=1326926
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Of Tao's performance of Schumann's piano concerto with the Pacific Symphony, Ken Iisaka of "San Francisco Classical Voice" commented: "With clear, articulate lines, Robert Schumann's passionate ardor towards Clara was expressed with determination, through deliberate tempos. Rather than letting the music be overly sentimental, rendering it a torrent of rage, Tao illustrated its volatile, bipolar personality with an unusual level of clarity and dryness. It almost felt as if the music gave a third-person account of the composer, rather than the music being by Schumann himself. Tao’s fresh perspective laid strong emphasis on the music’s architecture." Another reviewer thought that, in his rendition of "Rhapsody in Blue", Tao "bent the rhythms at times, showing his mastery of jazz style without disturbing his rapport with the accompanying [Asheveille Symphony] orchestra. He found connections and bridges that I had been unaware of, observed pauses that emphasized the importance of silence in the midst of music, and generally convinced the audience that this was a performance to remember." Anthony Tommasini of "The New York Times" reviewed one of Tao's "Crypt Sessions" recitals at the Church of the Intercession in Harlem, New York (Tao substituted on two days' notice for an ailing David Greilsammer), writing:
https://en.wikipedia.org/wiki?curid=33615494
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Archaeologists are bound to conduct their investigations to a high standard and observe intellectual property laws, health and safety regulations, and other legal obligations. Archaeologists in the field are required to work towards the preservation and management of archaeological resources, treat human remains with dignity and respect, and encourage outreach activities. Sanctions are in place for those professionals who do not observe these ethical codes. Questions regarding archaeological ethics first began to arise during the 1960s and 1970s in North America and Western Europe. A UNESCO ratification to protect world culture in 1970 was one of the earliest actions to implement ethical standards. Archaeologists conducting ethnoarchaeological research, which involves the study of living people, are required to follow guidelines set by the Nuremberg Code (1947) and the Declaration of Helsinki (1964).
https://en.wikipedia.org/wiki?curid=2607695
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In March 1958, while the United States Naval Research Laboratory (NRL) was heavily involved in Project Vanguard, the United States Navy's effort to launch a satellite, NRL engineer Reid D. Mayo determined that a Vanguard derivative could be used to map Soviet missile sites. Mayo had previously developed a system for submarines whereby they could evade anti-submarine aircraft by picking up their radar signals. Physically small and mechanically robust, it could be adapted to fit inside the small Vanguard frame. Mayo presented the idea to Howard Lorenzen, head of the NRL's countermeasures branch. Lorenzen promoted the idea within the Department of Defense (U.S. DoD), and six months later the concept was approved under the name "Tattletale". President Eisenhower approved full development of the program on 24 August 1959.
https://en.wikipedia.org/wiki?curid=5511670
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The seventh-oldest building on campus, Lustrat Hall was originally built in 1847, north of its current location. Named after its last faculty occupant, it is the only remaining faculty residence house from Old North Campus. Used for a variety of purposes in the past, the building most recently houses the Office of Legal Affairs. Built in 1874, Moore College is the only remaining building constructed during post-Civil War Reconstruction. Originally home to the College of Agriculture and Mechanic Arts, Moore College currently houses the university's Honors Program. The Holmes/Hunter Academic Building was simply known as the Academic Building when it was originally assembled in 1905. Following a Beaux-Arts architectural design by engineering professor Charles Strahan, the building was constructed by inserting a new building in between the older Ivy Building and Old Library. In 2001, the building was renamed after the first two African-American students at UGA. It houses the Office of the Registrar, and several other administrative offices. Also listed in the National Register of Historic Places is the Founders Memorial Garden which is named in honor of the Ladies Garden Club of Athens. Founded in 1891, it was the first garden club in the United States.
https://en.wikipedia.org/wiki?curid=378232
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Frank Woodbridge Cheney (born 5 June 1832) was a son of Charles. After graduation at Brown University in 1854, he joined the Cheney Brothers operations at Hartford. He volunteered for the Civil War in 1862 and became lieutenant colonel of the 16th Connecticut Volunteers. The regiment went to the front on 29 August, 1,010 strong but undisciplined and almost wholly ignorant of drill. The Confederates were beginning the invasion of Maryland that ended in repulse at Antietam, and all available troops were hurried forward to meet them irrespective of experience as soldiers. On 12 September, Frank Cheney led his regiment of recruits in a skirmish that proved preliminary to the battle of Antietam, in which engagement he was severely wounded, late in the afternoon, while endeavoring to rally his men, who, never having had a battalion drill, had been thrown into disorder by the enemy's fire. Cheney's wound proved so serious that he was obliged to retire from the service on 24 December 1862. In 1863, Frank married Mary Bushnell, daughter of Horace Bushnell. They had 12 children. Frank traveled in Europe, China, and Japan, studying the silk industries of those countries, and joined Cheney Brothers as its treasurer. His eldest son Horace B. Cheney followed in his footsteps.
https://en.wikipedia.org/wiki?curid=25729271
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During the late 1940s and the early 1950s, he worked very hard on producing some major theoretical statements. In 1951, Parsons published two major theoretical works, "The Social System" and "Toward a General Theory of Action". The latter work, which was coauthored with Edward Tolman, Edward Shils and several others, was the outcome of the so-called Carnegie Seminar at Harvard University, which had taken place in the period of September 1949 and January 1950. The former work was Parsons' first major attempt to present his basic outline of a general theory of society since "The Structure of Social Action" (1937). He discusses the basic methodological and metatheoretical principles for such a theory. He attempts to present a general social system theory that is built systematically from most basic premises and so he featured the idea of an interaction situation based on need-dispositions and facilitated through the basic concepts of cognitive, cathectic, and evaluative orientation. The work also became known for introducing his famous pattern variables, which in reality represented choices distributed along a "Gemeinschaft" vs. "Gesellschaft" axis.
https://en.wikipedia.org/wiki?curid=54041
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The ketimine Mannich reaction is an asymmetric synthetic technique using differences in starting material to push a Mannich reaction to create an enantiomeric product with steric and electronic effects, through the creation of a ketimine group. Typically, this is done with a reaction with proline or another nitrogen-containing heterocycle, which control chirality with that of the catalyst. This has been theorized to be caused by the restriction of undesired (E)-isomer by preventing the ketone from accessing non-reactive tautomers. Generally, a Mannich reaction is the combination of an amine, a ketone with a β-acidic proton and aldehyde to create a condensed product in a β-addition to the ketone. This occurs through an attack on the ketone with a suitable catalytic-amine unto its electron-starved carbon, from which an imine is created. This then undergoes electrophilic addition with a compound containing an acidic proton (which is an enol). It is theoretically possible for either of the carbonyl-containing molecules to create diastereomers, but with the addition of catalysts which restrict addition as of the enamine creation, it is possible to extract a single product with limited purification steps and in some cases as reported by List et al.; practical one-pot syntheses are possible. The process of selecting a carbonyl-group gives the reaction a direct versus indirect distinction, wherein the latter case represents pre-formed products restricting the reaction's pathway and the other does not. Ketimines selects a reaction group, and circumvent a requirement for indirect pathways.
https://en.wikipedia.org/wiki?curid=69092297
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The principle of parabolic reflectors has been known since classical antiquity, when the mathematician Diocles described them in his book "On Burning Mirrors" and proved that they focus a parallel beam to a point. Archimedes in the third century BCE studied paraboloids as part of his study of hydrostatic equilibrium, and it has been claimed that he used reflectors to set the Roman fleet alight during the Siege of Syracuse. This seems unlikely to be true, however, as the claim does not appear in sources before the 2nd century CE, and Diocles does not mention it in his book. Parabolic mirrors and reflectors were also studied extensively by the physicist Roger bacon in the 13th century AD. James Gregory, in his 1663 book "Optica Promota" (1663), pointed out that a reflecting telescope with a mirror that was parabolic would correct spherical aberration as well as the chromatic aberration seen in refracting telescopes. The design he came up with bears his name: the "Gregorian telescope"; but according to his own confession, Gregory had no practical skill and he could find no optician capable of actually constructing one. Isaac Newton knew about the properties of parabolic mirrors but chose a spherical shape for his Newtonian telescope mirror to simplify construction. Lighthouses also commonly used parabolic mirrors to collimate a point of light from a lantern into a beam, before being replaced by more efficient Fresnel lenses in the 19th century. In 1888, Heinrich Hertz, a German physicist, constructed the world's first parabolic reflector antenna.
https://en.wikipedia.org/wiki?curid=192590
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Chemical looping gasification (CLG) differs from the CLR in that it uses solid fuels such as coal and biomass instead of gaseous fuels as feedstocks. The operating principles for the CLG is similar to CLR. For solid feedstocks, devolatilization and pyrolysis of the solid fuel occur when the solid fuels are introduced into the reducer and mixed with the oxygen carrier particles. With the fluidized bed reducer, the released volatiles, including light organic compounds and tars, may channel through the reducer and exit with the syngas. The light organic compounds may reduce the purity of the syngas, while the tars may accumulate in downstream pipelines and instruments. For example, the carbon efficiency using the coal CLG fluidized bed reducer may vary from 55% to 81%, whereas the carbon efficiency using the coal moving bed reducer can reach 85% to 98%. The syngas derived from the biomass CLG fluidized bed reducer may consist of up to 15% methane, while the syngas derived from the biomass CLG moving bed reducer can reach a methane concentration of less than 5%. In general, increasing the temperature of the CLG system can promote volatile and char conversion. This may also promote the full oxidation side reaction resulting in an increased CO concentration in the syngas. Additional equipment for gas cleanup including scrubber, catalytic steam reformer and/or tar reformer may be necessary downstream of the CLG system in order to remove or convert the unwanted byproducts in the syngas stream. Char, the remaining solid from the devolatilization and reactions, requires additional time for conversion. For a fluidized bed reducer with particle back mixing, unconverted char may leave the reducer with the reduced metal oxide particles. A carbon stripper may be needed at the solid outlet of the fluidized bed reducer to allow the unconverted char to be separated from the oxygen carriers. The char can be recycled back to the reducer for further conversion.
https://en.wikipedia.org/wiki?curid=57712865
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CGIS was an improvement over "computer mapping" applications as it provided capabilities for data storage, overlay, measurement, and digitizing/scanning. It supported a national coordinate system that spanned the continent, coded lines as arcs having a true embedded topology and it stored the attribute and locational information in separate files. As a result of this, Tomlinson has become known as the "father of GIS", particularly for his use of overlays in promoting the spatial analysis of convergent geographic data. CGIS lasted into the 1990s and built a large digital land resource database in Canada. It was developed as a mainframe-based system in support of federal and provincial resource planning and management. Its strength was continent-wide analysis of complex datasets. The CGIS was never available commercially.
https://en.wikipedia.org/wiki?curid=12398
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The A319 design is a shortened fuselage, minimum change derivative of the A320 with its origins in the 130- to 140-seat SA1, part of the Single-Aisle studies. The SA1 was shelved as the consortium concentrated on its bigger siblings. After healthy sales of the A320/A321, Airbus re-focused on what was then known as the "A320M-7", meaning A320 "minus seven fuselage frames". It would provide direct competition for the 737-300/-700. The shrink was achieved through the removal of four fuselage frames fore and three aft the wing, cutting the overall length by . Consequently, the number of overwing exits was reduced from four to two. High-density A319s, such as 156-seat aircraft used by easyJet, retain four overwing exits. The bulk-cargo door was replaced by an aft container door, which can take in reduced height LD3-45 containers. Minor software changes were made to accommodate the different handling characteristics; otherwise the aircraft is largely unchanged. Power is provided by the CFM56-5A or V2500-A5, derated to , with option for thrust.
https://en.wikipedia.org/wiki?curid=164932
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A common approach to program social cues into robots is to first study human–human behaviors and then transfer the learning. For example, coordination mechanisms in human–robot collaboration are based on work in neuroscience which examined how to enable joint action in human–human configuration by studying perception and action in a social context rather than in isolation. These studies have revealed that maintaining a shared representation of the task is crucial for accomplishing tasks in groups. For example, the authors have examined the task of driving together by separating responsibilities of acceleration and braking i.e., one person is responsible for accelerating and the other for braking; the study revealed that pairs reached the same level of performance as individuals only when they received feedback about the timing of each other's actions. Similarly, researchers have studied the aspect of human–human handovers with household scenarios like passing dining plates in order to enable an adaptive control of the same in human–robot handovers. Another study in the domain of Human Factors and Ergonomics of human–human handovers in warehouses and supermarkets reveal that Givers and Receivers perceive handover tasks differently which has significant implications for designing user-centric human–robot collaborative systems. Most recently, researchers have studied a system that automatically distributes assembly tasks among co-located workers to improve co-ordination.
https://en.wikipedia.org/wiki?curid=3186372
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Tansley's introduction to ecology came in 1898 when he read Warming's "Plantesamfund" (in its German translation, "Lehrbuch der ökologischen Pflanzengeographie"). Reading the book provoked him to "[go] out into the field to see how far one could match the plant communities Warming had described for Denmark in the English countryside". In 1903 he learned of the work done by the Smith brothers in mapping the vegetation of Scotland and Yorkshire. The work was initiated by Robert Smith and continued by his brother, William Gardner Smith (in conjunction with Charles Edward Moss) after Robert's death. In 1904 Tansley suggested the formation of a central body for the systematic survey and mapping of the British Isles. This led to the establishment of the Central Committee for the Survey and Study of British Vegetation by Tansley, Moss, William Smith and T. W. Woodhead, with the support of Marcel Hardy, F. J. Lewis, Lloyd Praeger and W. M. Rankin. These eight formed the original committee, with Tansley as its leader. F. W. Oliver later joined the group as its ninth member. The name of the group was later shortened to the British Vegetation Committee. The aim of the group was to coordinate ongoing studies and standardise the methodology being used. The committee met twice more in 1905 and produced a six-page pamphlet, "Suggestions for Beginning Survey Work on Vegetation".
https://en.wikipedia.org/wiki?curid=608043
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Recognized for his invention of bicycle-handlebar-inspired tubular steel furniture, Breuer lived off his design fees at a time in the late 1920s and early 1930s when the architectural commissions he was looking for were few and far-between. The structural characteristics of his wooden furniture showed the influence of Dutch designers Gerrit Rietveld and Theo van Doesburg. He was known to such giants as Le Corbusier and Mies van der Rohe, whose architectural vocabulary he was later to adapt as part of his own, but hardly considered an equal by them who were his senior by 15 and 16 years. Despite the widespread popular belief that one of the most famous of Breuer's tubular steel chairs, the Wassily Chair was designed for Breuer's friend Wassily Kandinsky, it was not; Kandinsky admired Breuer's finished chair design, and only then did Breuer make an additional copy for Kandinsky's use in his home. When the chair was re-released in the 1960s, it was named "Wassily" by its Italian manufacturer, who had learned that Kandinsky had been the recipient of one of the earliest post-prototype units.
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Even at such long odds, the danger was sufficiently great to be taken seriously. Thomson, at Imperial College London, and Mark Oliphant, an Australian physicist at the University of Birmingham, were tasked with carrying out a series of experiments on uranium. By February 1940, Thomson's team had failed to create a chain reaction in natural uranium, and he had decided that it was not worth pursuing. But at Birmingham, Oliphant's team had reached a strikingly different conclusion. Oliphant had delegated the task to two German refugee scientists, Rudolf Peierls and Otto Frisch, who could not work on the University's radar project because they were enemy aliens and therefore lacked the necessary security clearance. They calculated the critical mass of a metallic sphere of pure uranium-235, the only fissile isotope found in significant quantity in nature, and found that instead of tons, as everyone had assumed, as little as would suffice, which would explode with the power of thousands of tons of dynamite.
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Energy-based generative neural networks is a class of generative models, which aim to learn explicit probability distributions of data in the form of energy-based models whose energy functions are parameterized by modern deep neural networks. Its name is due to the fact that this model can be derived from the discriminative neural networks. The parameter of the neural network in this model is trained in a generative manner by Markov chain Monte Carlo(MCMC)-based maximum likelihood estimation. The learning process follows an <nowiki>"</nowiki>analysis by synthesis<nowiki>"</nowiki> scheme, where within each learning iteration, the algorithm samples the synthesized examples from the current model by a gradient-based MCMC method, e.g., Langevin dynamics, and then updates the model parameters based on the difference between the training examples and the synthesized ones. This process can be interpreted as an alternating mode seeking and mode shifting process, and also has an adversarial interpretation. The first energy-based generative neural network is the generative ConvNet proposed in 2016 for image patterns, where the neural network is a convolutional neural network. The model has been generalized to various domains to learn distributions of videos, and 3D voxels. They are made more effective in their variants. They have proven useful for data generation (e.g., image synthesis, video synthesis, 3D shape synthesis, etc.), data recovery (e.g., recovering videos with missing pixels or image frames, 3D super-resolution, etc), data reconstruction (e.g., image reconstruction and linear interpolation ).
https://en.wikipedia.org/wiki?curid=63637933
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These ships share their anti-air warfare suite with the Royal Netherlands Navy's frigates and the German Navy's frigates. The sensors of this suite include the long range surveillance radar SMART-L (passive electronically scanned array) and the multi-function radar APAR active electronically scanned array. The SMART-L and APAR are highly complementary in the sense that SMART-L is an L band radar, providing very long range surveillance, while APAR is an I band radar, providing precise target tracking, a highly capable horizon search capability, and missile guidance using the Interrupted Continuous Wave Illumination (ICWI) technique, thus allowing guidance of 32 semi-active radar homing missiles in flight simultaneously, including 16 in the terminal guidance phase. The primary anti-air weapons are the medium-range Evolved Sea Sparrow missile and the area defence SM-2 IIIA. The Mk 41 Vertical Launch System is used to house and launch these missiles. Depending on the number of Harpoon launchers installed, up to 24 Evolved Sea Sparrow missile and 32 SM-2 IIIA or SM-6 may be carried.
https://en.wikipedia.org/wiki?curid=21927436
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One example of where particular genes may be important in vertebrate animals for heterosis is the major histocompatibility complex (MHC). Vertebrates inherit several copies of both MHC class I and MHC class II from each parent, which are used in antigen presentation as part of the adaptive immune system. Each different copy of the genes is able to bind and present a different set of potential peptides to T-lymphocytes. These genes are highly polymorphic throughout populations, but are more similar in smaller, more closely related populations. Breeding between more genetically distant individuals decreases the chance of inheriting two alleles that are the same or similar, allowing a more diverse range of peptides to be presented. This, therefore, gives a decreased chance that any particular pathogen will not be recognised, and means that more antigenic proteins on any pathogen are likely to be recognised, giving a greater range of T-cell activation, so a greater response. This also means that the immunity acquired to the pathogen is against a greater range of antigens, meaning that the pathogen must mutate more before immunity is lost. Thus, hybrids are less likely to succumb to pathogenic disease and are more capable of fighting off infection. This may be the cause, though, of autoimmune diseases.
https://en.wikipedia.org/wiki?curid=646125
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The Predator was a fire-and-forget weapon utilizing a system called predicted line of sight (PLOS). In this system, the operator tracks the target for a short time (at least 2 seconds and no more than 12) before launch. This data is then combined with known missile flight performance to predict a flight path that will intercept the target's course, and program the missile's autopilot system. An inertial guidance unit is incorporated into the autopilot to compensate for crosswind and other factors encountered in flight. The original FGM-172A was an "overfly top attack" (OTA) type and used a downward-facing dual laser and magnetic sensor to detect a target and trigger detonation of the warhead. The laser sensor would locate the positions of the leading and trailing edges of a vehicle, and the magnetic sensor would confirm the position of the vehicle. Once a target is detected, the FGM-172A would fire an explosively formed penetrator downward, into what was intended to be the thinner armor of a tank turret roof. The missile does not "lock on" to a specific target, rather, the FGM-172A would attack the first potential target it encountered during flight. For this reason, TM 10687A OR/C directs operators to avoid firing the weapon over destroyed vehicles.
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"Computer Gaming World" rated "X-COM" five stars out of five. Describing it as "one of those rare and dangerous games capable of drilling into your brain, putting a vice-grip on your imagination, and only releasing you when it has had enough", the magazine praised its detailed and varied combat system and lengthy gameplay, concluding "Resistance is futile". A preview of the PlayStation version in "Next Generation" called it "one of the best PC strategy games ever". GameSpot said, "put simply, "X-COM" is a "bona fide" modern classic, standing proudly alongside "Civilization" and "Populous" as a benchmark in the evolution of strategy gaming". "Electronic Gaming Monthly" stated of the PlayStation version that "any person who likes strategy games will fall in love with this title ... if you could afford to buy one game for the PS over the next year, "X-COM" would be it. It has it all and then some!" A reviewer for "Next Generation" criticized the PlayStation version for being little more than a straight port, arguing that the game could have been improved if the console's capabilities were used. However, he praised the game itself for sophisticated, enjoyable gameplay, and concluded, ""X-COM" was a smashing PC title, it's lost nothing of practical value in the translation, and makes a marvelous addition to the console market". "GamePro" disagreed: "You have to be a major sim-freak to enjoy "X-COM". It's an interesting and complex game about planet colonizing, but the extensive manuals and one-dimensional music really bore you to alien tears after a while".
https://en.wikipedia.org/wiki?curid=668164
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As a consequence, there was a crisis in international confidence in Greece's ability to repay its sovereign debt, as reflected by the rise of the country's borrowing rates (although their slow rise – the 10-year government bond yield only exceeded 7% in April 2010 – coinciding with a large number of negative articles, has led to arguments about the role of international news media in the evolution of the crisis). In order to avert a default (as high borrowing rates effectively prohibited access to the markets), in May 2010 the other Eurozone countries, and the IMF, agreed to a "rescue package" which involved giving Greece an immediate € in bail-out loans, with more funds to follow, totaling €. In order to secure the funding, Greece was required to adopt harsh austerity measures to bring its deficit under control. Their implementation was to be monitored and evaluated by the European Commission, the European Central Bank and the IMF.
https://en.wikipedia.org/wiki?curid=12113
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One environmental benefit of meat production is the conversion of materials that might otherwise be wasted or turned into compost to produce food. A 2018 study found that, "Currently, 70 % of the feedstock used in the Dutch feed industry originates from the food processing industry." Examples of grain-based waste conversion in the United States include feeding livestock the distillers grains (with solubles) remaining from ethanol production. For the marketing year 2009–2010, dried distillers grains used as livestock feed (and residual) in the US was estimated at 25.5 million metric tons. Examples of waste roughages include straw from barley and wheat crops (edible especially to large-ruminant breeding stock when on maintenance diets), and corn stover. Also, small-ruminant flocks in North America (and elsewhere) are sometimes used on fields for removal of various crop residues inedible by humans, converting them to food.
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Since the release of DO-178B, there had been strong calls by DERs (FAA Designated Engineering Representatives) for clarification/refinement of the definitions and boundaries between the key DO-178B concepts of high-level requirements, low-level requirements, and derived requirements and a better definition of the exit/entry criteria between systems requirements and system design (see ARP4754) and that of software requirements and software design (which is the domain of DO-178B). Other concerns included the meaning of verification in a model-based development paradigm and considerations for replacing some or all software testing activities with model simulation or formal methods. The release of DO-178C and the companion documents DO-278A (Ground Systems), DO-248C (Additional information with rationale for each DO-178C objective), DO-330 (Tool Qualification), DO-331 (Modeling), DO-332 (Object Oriented), and DO-333 (Formal Methods) were created to address the issues noted. The SC-205 members worked with the SAE S-18 committee to ensure that ARP4754A and the above noted DO-xxx documents provide a unified and linked process with complementary criteria.
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In 2010 Captain Barry Crawford, a Special Tactics Officer, was awarded the Air Force Cross for heroism during a 14-hour battle near Laghman Province, Afghanistan, on May 4, 2010. Captain Crawford was the joint terminal attack controller attached to an Army Special Forces team along with Afghan commandos. The team conducted a night time helicopter assault into a village to gather intelligence. After sunrise they came under attack from enemy combatants and several Afghan soldiers were wounded. After calling for a medical evacuation Captain Crawford exposed himself to enemy gunfire by running out into the open in order to guide the helicopter to the landing zone. While he was guiding the helicopter in, one of his radio antennae was shot off of his back. After the helicopter took off, Captain Crawford and the Special Forces team managed to exfiltrate the area without American casualties. During the battle Captain Crawford coordinated close air support, calling in over 40 airstrikes from 33 different aircraft. The AH-64 helicopters and F-15E fighters which were called in eliminated enemy positions and combatants utilizing strafing runs, along with 500- to 2,000-pound bombs and Hellfire missile strikes. The special operations team suffered two Afghan commando casualties, but more than 80 insurgents were believed to have been killed during the engagement, including three high-ranking enemy commanders.
https://en.wikipedia.org/wiki?curid=39800708
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After the Casablanca conference, a twenty-person working committee of the central committee of the Communist Party of Germany (KPD) was formed with members of the National Committee for a Free Germany in Moscow on February 6, 1944. Working closely with Soviet authorities, the working committee composed the "action program of the bloc of militant democracy", in which goals such as the eradication of the National Socialist legacy, the creation food security, and the creation of an alliance between the workforce and "working" farmers were formulated for further the development of agriculture and rural areas. The action program called for land reform without addressing the circumstances. The KPD leadership was most experienced in urban environments and, due to their origins, wasn't able to precisely makes plans for agriculture and therefore limited themselves to applying Marxist theories. The concrete plans simply remained that small farmers were "natural allies" and landowners as undesirable. Edwin Hoernle was one of the few members in the KPD with any agricultural expertise and had warned Moscow of the economic consequences, however the expropriations persisted despite this.
https://en.wikipedia.org/wiki?curid=32811077
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Rosette and lower pitchers are either infundibular throughout or ovate and variably inflated. They are small, measuring only up to 7 cm in height by 4 cm in width. A pair of wings (≤3 mm wide) often runs down the upper third of the pitcher's ventral surface, bearing fringe elements around 5 mm long. Occasionally, the wings may be absent altogether. The peristome varies from cylindrical to slightly expanded and has a wavy outer margin. It is up to 12 mm wide and bears fine ribs up to 0.6 mm high and spaced up to 1 mm apart. On the inner margin of the peristome, these ribs terminate in teeth up to 1.5 mm long, with the largest located towards the rear. The pitcher mouth is round and slightly elongated towards the rear, although it rarely exhibits a neck. The pitcher lid or operculum is narrowly ovate or elliptic and measures up to 3.5 cm in length by 2 cm in width. On its lower surface, the lid bears a basal glandular crest or no appendages at all, as well as numerous circular nectar glands (0.3 mm in diameter), which are concentrated around the midline and crest. An unbranched, filiform spur (≤4 mm long) is inserted near the base of the lid. Unlike their aerial counterparts, lower pitchers vary greatly in pigmentation. The pitcher cup may be yellow, orange, red, or even purple, whereas the inner surface may be light yellow, light orange, or whitish. The peristome is usually darker than the rest of the pitcher, typically being dark orange to purple, although it may be creamy white and occasionally exhibits red stripes. The lid has a similar colour to the pitcher cup, usually having a darker upper surface with dark red speckles.
https://en.wikipedia.org/wiki?curid=12384207
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Active protection systems show a great deal of promise, both in counteracting ATGMs and unguided weapons. Compared to armor systems, they are very lightweight, can be fitted to almost any vehicle with the internal space for the control system and could, in the future, be a near-perfect defense against any missiles. The weaknesses of the systems include potential developments in missile design such as radar or IR decoys, which would drastically reduce their chance to intercept a missile, as well as technical challenges such as dealing with multiple missiles at once and designing a system that can cover a vehicle from any angle of attack. While these may be answered and allow for lightweight, highly maneuverable vehicles that are strongly defended against missiles and rockets that are extremely well suited for urban and guerrilla warfare. However, such a system is unlikely to be as effective against kinetic energy projectiles, making it a poor choice for fighting against tanks. As kinetic energy projectiles move faster than guided missiles. This often means that the sensors attached to an active protection system can't keep up. Testing in 2007 showed that explosive reactive armor, fitted to a T-72 had no impact on a missile fitted with a kinetic energy projectiles.
https://en.wikipedia.org/wiki?curid=37517
121,718
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A major change to the game was announced in July 2019, called "Role Queue". Prior to this, players in Quickplay and Competitive modes could select any heroes at any point in the match. With the Role Queue requires players to select one of the three roles, Damage, Tank, and Support, before QuickPlay or Competitive games, which limits them to playing and switching between those heroes for the duration of the game. Players then would be matched so that each team would have two of each role. Groups of players would need to make sure their group does not exceed this before joining a match. Changes were made to support the Role Queue: competitive players would have separate skill rankings for each role, while heroes like Brigitte, originally designs to have some flexible capabilities between roles, would be adjusted to better fit their intended role. The intent of the change according to Kaplan was to "improve match quality, give players more control over their gameplay experience, and provide more positive social experiences between teammates." However, many observers believed the change was needed to combat the popular "GOATS" composition - a three-tank, three-support team named for the Overwatch Contenders team that popularized this. GOATS proved difficult to disrupt by opposing teams unless they also played GOATS. The GOATS composition had been dominating both Overwatch League play for most of its 2019 season, and was very common in normal competitive play, causing players and viewers to become disinterested. The Role Queue eliminates GOATS and thus expected to bring new life to "Overwatch" according to journalists. The Role Queue was introduced on the PTR in July 2019, and a short 2-week competitive season was held in August 2019 to test the system across all platforms before its full planned release in September 2019.
https://en.wikipedia.org/wiki?curid=55762533
1,367,831
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He created a new concept of drawing perspectives. Supported by Walter Bernhardt, assistant professor of Applied Mechanics at Wichita State University, Kansas, his ideas were successfully implemented as mathematical formulae. Programmers subsequently entered these into the computer. Fetter was the team leader (supervisor) of this group. Due to the success of the first experiments, a Boeing research program was launched in November 1960 with Fetter as manager. The result of the research was registered as a "Planar Illustration Method and Apparatus" under US patent in November 1961 – Patent 1970 obtained with the number 3,519,997. The January 1965 issue of "Architectural Record" magazine described how Fetter had worked as a graphic designer in a team of engineers and programmers to create computer graphics.
https://en.wikipedia.org/wiki?curid=47805764
1,750,891
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Cetyl myristoleate was isolated for the first time by Dr. Harry Diehl at the Laboratory of Chemistry of the National Institute of Arthritis, Metabolic, and Digestive Diseases in Bethesda, Maryland. Dr. Diehl had tried to unsuccessfully induce polyarthritis in Swiss albino mice using Freund's adjuvant (heat-killed desiccated Mycobacterium butyricum) but realized that they were immune. Further investigation revealed that cetyl myristoleate was what was causing the mice to be immune to becoming arthritic. The compound was isolated and identified using thin layer chromatography. In order to validate his theory that cetyl myristoleate could prevent arthritis in rodents, Diehl injected two groups of rats with the arthritis-inducing Freund’s adjuvant. After 20 days, both groups had no visible sign of arthritis. Then, a group was re-injected with the adjuvant while the other group received an injection of cetyl myristoleate followed by an injection of the adjuvant 48 hours later. After 58 days of observation, the rats that had not received cetyl myristoleate injections had developed swelling, had grown on average 5.17 times less than the other group and were lethargic. On the other hand, the rats who received cetyl myristoleate injections were healthy and growing at a normal rate. The findings were first published in 1994 in the peer-reviewed American Journal of Pharmaceutical Sciences.
https://en.wikipedia.org/wiki?curid=20151949
1,483,031
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The contents of the "Surya Siddhanta" is written in classical Indian poetry tradition, where complex ideas are expressed lyrically with a rhyming meter in the form of a terse "shloka". This method of expressing and sharing knowledge made it easier to remember, recall, transmit and preserve knowledge. However, this method also meant secondary rules of interpretation, because numbers don't have rhyming synonyms. The creative approach adopted in the "Surya Siddhanta" was to use symbolic language with double meanings. For example, instead of one, the text uses a word that means moon because there is one moon. To the skilled reader, the word moon means the number one. The entire table of trigonometric functions, sine tables, steps to calculate complex orbits, predict eclipses and keep time are thus provided by the text in a poetic form. This cryptic approach offers greater flexibility for poetic construction.
https://en.wikipedia.org/wiki?curid=3948016
941,145
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At Ajmer the smaller screen arches are tentatively cusped, for the first time in India. By around 1300 true domes and arches with voussoirs were being built; the ruined Tomb of Balban (d. 1287) in Delhi may be the earliest survival. The Alai Darwaza gatehouse at the Qutb complex, from 1311, still shows a cautious approach to the new technology, with very thick walls and a shallow dome, only visible from a certain distance or height. Bold contrasting colours of masonry, with red sandstone and white marble, introduce what was to become a common feature of Indo-Islamic architecture, substituting for the polychrome tiles used in Persia and Central Asia. The pointed arches come together slightly at their base, giving a mild horseshoe arch effect, and their internal edges are not cusped but lined with conventionalized "spearhead" projections, possibly representing lotus buds. Jali, stone openwork screens, are introduced here; they already had been long used in temples.
https://en.wikipedia.org/wiki?curid=276879
286,709
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The Argo Steering Team made a 10-year report to OceanObs-2009 and received suggestions on how the array might be improved. These suggestions included enhancing the array at high latitudes, in marginal seas (such as the Gulf of Mexico and the Mediterranean) and along the equator, improved observation of strong boundary currents (such as the Gulf Stream and Kuroshio), extension of observations into deep water and the addition of sensors for monitoring biological and chemical changes in the oceans. In November 2012 an Indian float in the Argo array gathered the one-millionth profile (twice the number collected by research vessels during all of the 20th century) an event that was reported in several press releases. As can be seen in the plot opposite, by early 2018 the Bio-Argo program is expanding rapidly.
https://en.wikipedia.org/wiki?curid=1245135
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It was relaunched with more pages, more colour and issued bimonthly with new writers. The balance of the periodical was finely tuned to satisfy the needs of both new and more experienced growers. Rittershausen retired at the end of 2000 and was followed by Dr Henry Oakeley (b. 1941) for the first three issues for 2001. Following a review by the Royal Horticultural Society, Isobyl la Croix (b. 1933) was put in charge. She would go on to edit the journal for the next eight years, overseeing the transition to digital publishing. Before 2005 colour could only be on every other double page until the Royal Horticultural Society's publications department in Peterborough undertook the design. It heralded a revamp with a new cover, text in three rather than two columns and the news section expanded to four pages. At the end of 2008 the periodical became quarterly. Sarah Forsyth (b. 1972), who had a background in horticultural journalism, took over as editor in January 2010. She was joined by an editorial panel of six people and the news section expanded to six pages. She continued until James Armitage (b. 1976), editor of The Plantsman and previously a botanist at RHS Garden Wisley, was appointed as editor in early 2020.
https://en.wikipedia.org/wiki?curid=41720603
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Yang was born in Hefei, Anhui, China; his father, (; 1896–1973), was a mathematician, and his mother, Meng Hwa Loh Yang (), was a housewife. Yang attended elementary school and high school in Beijing, and in the autumn of 1937 his family moved to Hefei after the Japanese invaded China. In 1938 they moved to Kunming, Yunnan, where National Southwestern Associated University (Lianda), was located. In the same year, as a second year student, Yang passed the entrance examination and studied at Lianda. He received his bachelor's degree in 1942, with his thesis on the application of group theory to molecular spectra, under the supervision of Ta-You Wu. He continued to study graduate courses there for two years under the supervision of Wang Zhuxi, working on statistical mechanics. In 1944 he received his master's degree from Tsinghua University, which had moved to Kunming during the Sino-Japanese War (1937–1945). Yang was then awarded a scholarship from the Boxer Indemnity Scholarship Program, set up by the United States government using part of the money China had been forced to pay following the Boxer Rebellion. His departure for the United States was delayed for one year, during which time he taught in a middle school as a teacher and studied field theory.
https://en.wikipedia.org/wiki?curid=252062
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The volcanic field has an area of more than 5000 km and more than 300 individual structures and contains pyroclastic cones, lava domes and maars. The field erupted basaltic to foiditic lavas from the Pliocene to the Holocene in Columba volcano with phreatomagmatic activity, and fumaroles were observed in the 16th-18th centuries in the Sierra de Valenzuela territory. Earlier activity has been subdivided in several phases. The first affecting mostly the centre of the field is K-Ar dated between 8.7 and 6.4 Ma. A second phase occurred in the Pleistocene 1.3 Ma and 0.7 Ma. The maars involve both hard-substrate maars formed in metasediments of the basement and soft-substrate maars in Pliocene unconsolidated sediments. Both types of maars are distributed in NE-SW and NW-SE directions following faults established during the Miocene. During the lower Pliocene, the system underwent uplift and erosion. Some maars contain sediments including travertine possibly related to carbon dioxide emissions. Gas emissions, sometimes increased following earthquake activity, are common in the field and include hydrogen sulfide, CO and water.
https://en.wikipedia.org/wiki?curid=47211277
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In June 1989, the mission's instruments had been selected and work began on spacecraft hardware. A project team was formed in January 1993 and based at the European Space Research and Technology Centre (ESTEC) in Noordwijk, Netherlands. Prime contractor Dornier Satellitensysteme (a subsidiary of the former DaimlerChrysler Aerospace) was chosen in October 1994 after the mission was approved into the implementation phase, with development and construction beginning in March 1996 and March 1997, respectively. The XMM Survey Science Centre was established at the University of Leicester in 1995. The three flight mirror modules for the X-ray telescopes were delivered by Italian subcontractor Media Lario in December 1998, and spacecraft integration and testing was completed in September 1999.
https://en.wikipedia.org/wiki?curid=227960
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