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The war in Europe involved aid to Britain, her allies, and the Soviet Union, with the US supplying munitions until it could ready an invasion force. US forces were first tested to a limited degree in the North African Campaign and then employed more significantly with British Forces in Italy in 1943–45, where US forces, representing about a third of the Allied forces deployed, bogged down after Italy surrendered and the Germans took over. Finally the main invasion of France took place in June 1944, under General Dwight D. Eisenhower. Meanwhile, the US Army Air Forces and the British Royal Air Force engaged in the area bombardment of German cities and systematically targeted German transportation links and synthetic oil plants, as it knocked out what was left of the Luftwaffe post Battle of Britain in 1945. Being invaded from all sides, it became clear that Germany would lose the war. Berlin fell to the Soviets in May 1945, and with Adolf Hitler dead, the Germans surrendered.
https://en.wikipedia.org/wiki?curid=4653534
122,379
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Major indoor sources for bioaerosols at residential homes include human occupants, pets, house dust, organic waste, as well as the heating, ventilation and air-conditioning (HVAC) system. Several studies have identified human activities as an important source for indoor bioaerosols. Human bodies can generate bioaerosols directly through activities like talking, sneezing, and coughing, while other residential activities (i.e., washing, flushing toilet, sweeping floor) can generate bioaerosols indirectly. Since microorganisms can accumulate and grow on dust particles, house dust is a potential source of bioaerosols. In a study by Wouters "et al"., they investigated the effects of indoor storage of organic household waste on microbial contamination among 99 households in the Netherlands in the summer of 1997, and indicated that “increased microbial contaminant levels in homes are associated with indoor storage of separated organic waste”, which might elevate “the risk of bioaerosol-related respiratory symptoms in susceptible people”. However, the analysis by Wouters "et al". was based on the collected samples of settled house dust, which might not serve as a strong indicator for bioaerosols suspended in the air. Other materials in residential buildings, such as food stuffs, house plants, textiles, wood material and furniture stuffing can also become bioaerosol sources when water content is appropriate for microorganisms to grow.
https://en.wikipedia.org/wiki?curid=25400387
2,050,437
17,560
Berkeley alumni—often generous benefactors—have long been among the billionaire ranks, their largess giving rise to many of the campus' eponymous schools, pavilions, centers, institutes, and halls, and with some of the more prominent being J. Paul Getty, Ann Getty, Sanford Diller and Helen Diller, Donald Fisher, Flora Lamson Hewlett, David Schwartz (Bio-Rad) and members of the Haas (Walter A. Haas, Rhoda Haas Goldman, Walter A. Haas Jr., Peter E. Haas, Bob Haas), Hearst, and Bechtel families. There are at least 30 living alumni billionaires: Gordon Moore (Intel founder), James Harris Simons (Renaissance Technologies), Masayoshi Son (SoftBank), Jon Stryker (Stryker Medical Equipment), Eric Schmidt (former Google Chairman) and Wendy Schmidt, Michael Milken, Bassam Alghanim, Kutayba Alghanim, Charles Simonyi (Microsoft), Cher Wang (HTC), Robert Haas (Levi Strauss & Co.), Carlos Rodriguez-Pastor (Interbank, Peru), Fayez Sarofim, Daniel S. Loeb, Paul Merage, David Hindawi, Orion Hindawi, Bill Joy (Sun Microsystems founder), Victor Koo, Tony Xu (DoorDash), Lowell Milken, Nathaniel Simons and Laura Baxter-Simons, Elizabeth Simons and Mark Heising, Oleg Tinkov, Liong Tek Kwee (BS 1968), Liong Seen Kwee (BS 1974) and Alice Schwartz.
https://en.wikipedia.org/wiki?curid=31922
17,554
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Percolation has been developed outside of the cognitive sciences; however, its application in the field has proven it to be a useful tool for understanding neural processes. Researchers have focused their attention not only studying how neural activity is diffused across networks, but also how percolation and its aspect of phase transition can affect decision making and thought processes. Percolation theory has enabled researchers to better understand many psychological conditions, such as epilepsy, disorganized schizophrenia and divergent thinking. These conditions are often indicative of percolating clusters and their involvement in propagating the excess firing of neurons. Seizures occur when neurons in the brain fire simultaneously, and often these seizures can occur in one part of the brain which may then transfer to other parts. Researchers are able to facilitate a better understanding of these conditions because "the neurons involved in a seizure are analogous to the sites in a percolating cluster". Disorganized schizophrenia is more complex as the activity is indicative activity in a percolating cluster; however, some researchers have suggested that the percolation of information does not occur in a small cluster but on a global functional scale. Attention as well as percolation also plays a key role in disorganized and divergent thinking; however, it is more likely that directed percolation, that is a directionally controlled percolation, is more useful to study divergent thinking and creativity.
https://en.wikipedia.org/wiki?curid=39199253
2,130,679
1,410,000
Beckman saw an opportunity, and rethinking the project, decided to create a complete chemical instrument which could be easily transported and used by nonspecialists. By October 1934, he had registered patent application US Patent No. 2,058,761 for his "acidimeter", later renamed the pH meter. The Arthur H. Thomas Company, a nationally known scientific instrument dealer based in Philadelphia, was willing to try selling it. Although it was priced expensively at $195, roughly the starting monthly wage for a chemistry professor at that time, it was significantly cheaper than the estimated cost of building a comparable instrument from individual components, about $500. The original pH meter weighed in at nearly 7 kg, but was a substantial improvement over a benchful of delicate equipment. The earliest meter had a design glitch, in that the pH readings changed with the depth of immersion of the electrodes, but Beckman fixed the problem by sealing the glass bulb of the electrode.
https://en.wikipedia.org/wiki?curid=315197
1,409,208
1,885,667
When the egg is buried deeply enough, the bacteria decomposing the egg are cut off from oxygen and begin to power their metabolisms using different energy sources. These processes can result in certain minerals being precipitated out of the groundwater selectively. The bacteria also dispose of metabolic waste using ions. Ken Carpenter observes that one common method links CO to Ca2+ ions to produce calcium carbonate. Some of the bacteria involved in the decay process use the conversion of nitrogento ammonia to power their metabolisms. When this ammonia leaks out of the egg it raises the surrounding pH into the alkaline and can change what minerals will precipitate out of the water. The organic material in the eggshell itself can lead to the precipitation of calcite out of solution. This often causes fossil eggshell to be covered in a thin layer of calcite that complicates the identification process. However, since eggshells are usually chiefly composed of calcite anyway the eggshell itself is mostly composed of the original calcite it had in life. The lack of change in composition and structure despite undergoing fossilization allows scientists to study the original structure of the shell.
https://en.wikipedia.org/wiki?curid=39701693
1,884,586
1,034,521
These programs have helped to meet regulatory challenges by incorporating pollution control technologies into a portfolio of cost-effective regulatory compliance options for conventional and developmental coal-fired power plants. This portfolio has positioned the U.S. as a top exporter of clean coal technologies such as those used for , and mercury, and more recently for carbon capture, consistent with a goal of deploying advanced coal-based power systems in commercial service with improved efficiency and environmental performance to meet increasingly stringent environmental regulations and market demands, leading to widespread, global deployment which will contribute to significant reductions in greenhouse gas emissions. The DOE continues its programs and initiatives through regional sequestration partnerships, a carbon sequestration leadership forum and the Carbon Sequestration Core Program, a CCS research and development program.
https://en.wikipedia.org/wiki?curid=2423894
1,033,984
202,094
The EMD SD70 typically has the smaller "spartan cab", typical on preceding SD60 models, instead of the larger "comfort cab" used on later models. Notable differences between the SD70 and SD60 are the radial steering EMD HTCR truck instead of the older HTC truck, and the SD70's overall length of 72 ft 4in, the older SD60 being 71 ft 2 in. The SD70 also rides higher as its frame is approximately higher than the SD60. This model is equipped with direct current (DC) traction motors, which simplifies the locomotive's electrical system by obviating the need for computer-controlled inverters (as are required for alternating current (AC) power). It is equipped with the , 16-cylinder EMD 710 prime mover. One hundred and twenty-two examples of this model locomotive were produced for Norfolk Southern (NS), Conrail (CR), Illinois Central (IC) and Southern Peru Copper Corporation (SPCC). Conrail's assets were split between Norfolk Southern and CSX in 1999, and all 24 of Conrail's SD70 units went to NS. Other than the CR paint scheme these units were built to NS specifications and numbered (2557 - 2580) in series with Norfolk Southern's already purchased SD70s.
https://en.wikipedia.org/wiki?curid=1360570
201,991
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The first building was in 1708 when a "school house" was built in part of the filled-up moat outside the city walls. In 1840 additional rooms were constructed and in both 1882 and 1893, additions were made. In the late 1960s, the buildings were demolished, and the site is now a car park next to a nightclub. The school's playing fields and swimming pool were originally by the River Medway off Rochester Esplanade; they are now off Maidstone Road, Rochester, next to the area known as Priestfields (not to be confused with Gillingham FC's stadium, Priestfield). An annexe (now known as P block) was built at the Maidstone Road site in the 1950s, housing only the second and third years. By the early 1960s, the entire first and second years, and 3A and 3B were located there and 3G and 3L moved to the temporary buildings in the upper yard at the High Street site. In autumn 1968, the whole school moved to a new building on the site. Initially, this featured a main block, hall, sports hall, gymnasium, 25-metre indoor swimming pool and science block. The school's music block was expanded in 2005 to include a new teaching room and several new practice rooms.
https://en.wikipedia.org/wiki?curid=3256243
1,401,875
698,413
The prepared coal charge in the coal tower is drawn by a charging car on the top of the batteries and charged into the ovens as per sequence. The charged coal is gradually heated by the heating wall of the oven in the absence of air to attain a temperature of 1000°-1050 °C at the central axis of the coke mass toward the end of coking period. the coking period is generally specified between 16 hrs and 19 hrs depending on oven condition and production requirement. the volatile matter of coal liberated during carbonization is collected in gas collecting mains in the form of raw coke oven gas passing through stand pipes and direct contact cooling with ammonia liquor spray. The gas cooled from 800 °C is drawn to coal chemical plant by exhauster. The residual coke is pushed out of the oven by pusher car through a guide into coke bucket. The red-hot coke is taken to coke dry cooling plant for cooling. There are 4 batteries, each having 67 ovens each. Each oven can hold 32 tons of dry coal charge. The volumetric capacity of each oven is 41.6 cum the heat for carbonation is supplied by under firing of coke oven gas having CV of 4200 Kcal/Nm3 of mixture of BF gas & CO gas having 900 Kcal/Nm3. The heating system of batteries is of under jet, compound type having twin-heating flues with re-circulation of waste gases.
https://en.wikipedia.org/wiki?curid=28835061
698,049
1,750,779
Falkow had on-going severe anxiety throughout his career. Due to his anxiety early in his career he avoided conferences, airplanes, and giving presentations in general due to the fact that he would shake and sweat noticeably during them. Falkow described his struggle with his mental health as an "uneasy truce" with his "demons" later on in his career as he learned various coping mechanisms. Because of his anxiety during public speaking, he often employed humor in his teaching and presentations to help cope with the tension of a silent audience, which also lead to most of the audience members finding his talks memorable and enjoyable. Falkow kept his condition a secret from his colleagues during his early career, only privately revealing to Arthur Saz, the chair of microbiology at Georgetown University School of Medicine, that he received and benefited from psychoanalysis treatment. Health insurance for mental health treatment was much better for military employees than academics at the time, and a major reason Falkow continued to work at the Walter Reed Army Institute of Research for as long as he did early in his career, but Falkow agreed to a job at Georgetown University because of this disclosure, upon which the chair privately organized Falkow's healthcare benefits to cover his psychoanalysis treatments.
https://en.wikipedia.org/wiki?curid=1920745
1,749,793
1,494,698
There are several ways to prevent and control manifestation of "A. penicillioides" and its biological contaminants. Fungal detector can be used to determine in advance whether a place is damp and supports fungal growth, which allow actions to be taken before contamination occurs. The fungal detector encapsulating fungal spores is exposed to test site, and fungal response is measured. Greatest response indicates the type of fungi that would contaminate the site. At 71% relative humidity, such as dry areas in homes," A. penicillioides" showed greatest response and form many spores. The formation of new spores indicate that life cycle of "A. penicillioides" is progressed to completion, and propagation of these new spores can lead to contamination. A biosensor has also been used to detect volatile organic compounds, such as formaldehyde. Formaldehyde is detected in air based on fungal growth inhibition, reflected by suppressed mycelium growth and absorbance. This biosensor is advantageous in that it allows measuring of toxicity at lower cost than HPLC and GC/MS. However, it is difficult to identify the toxic substance and concentration of toxicity in a sample by this biosensor. Some other prevention strategies are controlling liquid water, managing indoor condensation and selecting materials that minimize mold growth.
https://en.wikipedia.org/wiki?curid=40821668
1,493,857
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Nobel laureate Paul Sabatier worked in the late 1890s to develop the chemistry of hydrogenation. Whereas Sabatier considered hydrogenation of only vapors, the German chemist Wilhelm Normann showed in 1901 that liquid oils could be hydrogenated, and patented the process in 1902. Normann's hydrogenation process made it possible to stabilize affordable whale oil or fish oil for human consumption, a practice kept secret to avoid consumer distaste. During the years 1905–1910, Normann built a fat-hardening facility in the Herford company. At the same time, the invention was extended to a large-scale plant in Warrington, England, at Joseph Crosfield & Sons, Limited. It took only two years until the hardened fat could be successfully produced in the plant in Warrington, commencing production in late 1909. The initial year's production totalled nearly 3,000 tonnes.
https://en.wikipedia.org/wiki?curid=65165314
809,343
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The broadcast media industry is at a critical turning point in its development, with many countries moving from analog to digital broadcasts. This move is made possible by the production of cheaper, faster and more capable integrated circuits. The chief advantage of digital broadcasts is that they prevent a number of complaints common to traditional analog broadcasts. For television, this includes the elimination of problems such as snowy pictures, ghosting and other distortion. These occur because of the nature of analog transmission, which means that perturbations due to noise will be evident in the final output. Digital transmission overcomes this problem because digital signals are reduced to discrete values upon reception and hence small perturbations do not affect the final output. In a simplified example, if a binary message 1011 was transmitted with signal amplitudes [1.0 0.0 1.0 1.0] and received with signal amplitudes [0.9 0.2 1.1 0.9] it would still decode to the binary message 1011— a perfect reproduction of what was sent. From this example, a problem with digital transmissions can also be seen in that if the noise is great enough it can significantly alter the decoded message. Using forward error correction a receiver can correct a handful of bit errors in the resulting message but too much noise will lead to incomprehensible output and hence a breakdown of the transmission.
https://en.wikipedia.org/wiki?curid=33094374
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In the early 2000s, Orbital continued expanding its missile defense systems business with a US$900 million award to develop, build, test and support interceptor booster vehicles. In 2006, Orbital conducted its 500th mission since the company's founding with products that included satellites, launch vehicles, and missile defense systems. In 2007, the first interplanetary spacecraft built by Orbital, Dawn was launched on an eight-year, three-billion-mile journey to the main asteroid belt between Mars and Jupiter. A major milestone in the company's history was in 2008 when it received a long-term NASA contract to provide cargo transportation services to and from the International Space Station (ISS) with a value of approximately US$1.9 billion for missions from 2011 to 2015. Orbital used its Cygnus spacecraft and Antares launch vehicle to transport cargo to ISS following the success of Cygnus Orb-D1 and Cygnus CRS Orb-1.
https://en.wikipedia.org/wiki?curid=742393
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In a study published in 2010, researchers from Beijing University studying ultrasound images of infants who fell ill in the 2008 contamination found that while most children in a rural Chinese area recovered, 12 per cent still showed kidney abnormalities six months later. "The potential for long-term complications after exposure to melamine remains a serious concern," the report said. "Our results suggest a need for further follow-up of affected children to evaluate the possible long-term impact on health, including renal function." Another 2010 follow-up study from Lanzhou University attributed the uric acid stone accumulation after ingestion of melamine to a rapid aggradation of metabolites such as cyanuric acid diamide (ammeline) and cyanuric acid and reported that urine alkalinization and stone liberalization were the most effective treatments.
https://en.wikipedia.org/wiki?curid=553468
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The sting apparatus, including the barbs, may have evolved specifically in response to predation by vertebrates, as the barbs do not usually function (and the sting apparatus does not detach) unless the sting is embedded in fleshy tissue. While the sting can also penetrate the membranes between joints in the exoskeleton of other insects (and is used in fights between queens), in the case of "Apis cerana japonica", defense against larger insects such as predatory wasps (e.g. Asian giant hornet) is usually performed by surrounding the intruder with a mass of defending worker bees, which vibrate their muscles vigorously to raise the temperature of the intruder to a lethal level ("balling"). Previously, heat alone was thought to be responsible for killing intruding wasps, but recent experiments have demonstrated the increased temperature in combination with increased carbon dioxide levels within the ball produce the lethal effect. This phenomenon is also used to kill a queen perceived as intruding or defective, an action known to beekeepers as 'balling the queen', named for the ball of bees formed.
https://en.wikipedia.org/wiki?curid=58261
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Beginning in 2017, a number of CBRS trial projects were initiated in various cities. In February 2017, Nokia, Alphabet and Qualcomm tested LTE technology in a CBRS-band broadcast of "live high-definition video of cars racing on a track in Las Vegas". In April, Kansas City, Missouri "approved a Google test of 3.5 GHz shared wireless in more than eight locations in that area for up to 18 months". In May, Google received permission from the FCC to test wireless technology within the CBRS band at four NASCAR race events held during the summer of 2017, in Bristol, Tennessee, Brooklyn, Michigan, Darlington, South Carolina, and Richmond, Virginia. By August 2017, Verizon Communications had formed a consortium "to carry out the first use of CBRS band 48 spectrum in a 4G LTE Advanced (LTE-A) carrier aggregation demonstration". In November 2017, the CBRS Alliance entered into an agreement with the Wireless Internet Service Providers Association (WISPA) "to cooperate closely in the advancement of the CBRS spectrum band".
https://en.wikipedia.org/wiki?curid=53487128
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The American botanist Asa Gray used the name "theistic evolution" in a now-obsolete sense for his point of view, presented in his 1876 book "Essays and Reviews Pertaining to Darwinism". He argued that the deity supplies beneficial mutations to guide evolution. St George Jackson Mivart argued instead in his 1871 "On the Genesis of Species" that the deity, equipped with foreknowledge, sets the direction of evolution (orthogenesis) by specifying the laws that govern it, and leaves species to evolve according to the conditions they experience as time goes by. The Duke of Argyll set out similar views in his 1867 book "The Reign of Law". The historian Edward J. Larson stated that the theory failed as an explanation in the minds of biologists from the late 19th century onwards as it broke the rules of methodological naturalism which they had grown to expect.
https://en.wikipedia.org/wiki?curid=328815
954,466
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Francium nitrate, sulfate, hydroxide, carbonate, acetate, and oxalate, are all soluble in water, while the iodate, picrate, tartrate, chloroplatinate, and silicotungstate are insoluble. The insolubility of these compounds are used to extract francium from other radioactive products, such as zirconium, niobium, molybdenum, tin, antimony, the method mentioned in the section above. The CsFr molecule is predicted to have francium at the negative end of the dipole, unlike all known heterodiatomic alkali metal molecules. Francium superoxide (FrO) is expected to have a more covalent character than its lighter congeners; this is attributed to the 6p electrons in francium being more involved in the francium–oxygen bonding. The relativistic destabilisation of the 6p spinor may make francium compounds in oxidation states higher than +1 possible, such as [FrF]; but this has not been experimentally confirmed. Francium perchlorate is produced by the reaction of francium chloride and sodium perchlorate. The francium perchlorate coprecipitates with caesium perchlorate. This coprecipitation can be used to isolate francium, by adapting the radiocaesium coprecipitation method of Lawrence E. Glendenin and C. M. Nelson. However, this method is unreliable in separating thallium, which also coprecipitates with caesium. Francium perchlorate's entropy is expected to be 42.7 e.u (178.7 J mol K).
https://en.wikipedia.org/wiki?curid=71903725
2,220,792
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An analysis of both of Foote's papers was published online in 2020 by Joseph D. Ortiz, a geology professor at Kent State University, and Jackson. Their printed findings in 2022 contain a description of Foote's methodology. They pointed out that although she did not cite specific works by other scientists, she referenced de Saussure, Alexander von Humboldt, and Edward Sabine. (Reed had previously noted that Foote had also referenced Henri Becquerel, Jean-Baptiste Biot, and Joseph Louis Gay-Lussac.) They also noted that Foote "did not measure the natural greenhouse effect of the earth's atmosphere", but rather studied the heating of gases inside glass vessels. The walls of these vessels would have blocked longwave infrared radiation from either entering or leaving, while allowing some heat to escape via conduction. Accordingly, her results did not directly indicate how the greenhouse effect operates in a natural atmosphere, but they did provide quantitative information about how gases, including greenhouse gases, absorb and radiate heat.
https://en.wikipedia.org/wiki?curid=49280323
652,710
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The highly elliptical orbits of the spacecraft initially reached a perigee of around 4 R (Earth radii, where 1 R = 6371 km) and an apogee of 19.6 R. Each orbit took approximately 57 hours to complete. The orbit has evolved over time; the line of apsides has rotated southwards so that the distance at which the orbit crossed the magnetotail current sheet progressively reduced, and a wide range of dayside magnetopause crossing latitudes were sampled. Gravitational effects impose a long term cycle of change in the perigee (and apogee) distance, which saw the perigees reduce to a few 100 km in 2011 before beginning to rise again. The orbit plane has rotated away from 90 degrees inclination. Orbit modifications by ESOC have altered the orbital period to 54 hours. All these changes have allowed Cluster to visit a much wider set of important magnetospheric regions than was possible for the initial 2-year mission, improving the scientific breadth of the mission.
https://en.wikipedia.org/wiki?curid=2493790
1,648,114
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In industrial plants, CCTV equipment may be used to observe parts of a process from a central control room, especially if the environments observed are dangerous or inaccessible to humans. CCTV systems may operate continuously or only as required to monitor a particular event. A more advanced form of CCTV, using digital video recorders (DVRs), provides recording for possibly many years, with a variety of quality and performance options and extra features (such as motion detection and email alerts). More recently, decentralized IP cameras, perhaps equipped with megapixel sensors, support recording directly to network-attached storage devices, or internal flash for completely stand-alone operation.
https://en.wikipedia.org/wiki?curid=87179
327,074
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The carbon electric filament lamp then in use was dim and expensive because it required a vacuum in its bulb. Nernst invented a solid-body radiator with a filament of rare-earth oxides, known as the Nernst glower, it is still important in the field of infrared spectroscopy. Continuous ohmic heating of the filament results in conduction. The glower operates best in wavelengths from 2 to 14 micrometers. It gives a bright light but only after a warm-up period. Nernst sold the patent for one million marks, wisely not opting for royalties because soon the tungsten filament lamp filled with inert gas was introduced. With his riches, Nernst in 1898 bought the first of the eighteen automobiles he owned during his lifetime and a country estate of more than five hundred hectares for hunting. He increased the power of his early automobiles by carrying a cylinder of nitrous oxide that he could inject into the carburetor. After eighteen productive years at Göttingen, investigating osmotic pressure and electrochemistry and presenting a theory of how nerves conduct, he moved to Berlin, and was awarded the title "Geheimrat"
https://en.wikipedia.org/wiki?curid=75876
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DIPs have been shown to play a role in pathogenesis of certain viruses. One study demonstrates the relationship between a pathogen and its defective variant, showing how regulation of DI production allowed the virus to attenuate its own infectious replication, decreasing viral load and thus enhance its parasitic efficiency by preventing the host from dying too fast. This also provides the virus with more time to spread and infect new hosts. DIP generation is regulated within viruses: the Coronavirus SL-III cis-acting replication element (shown in the image) is a higher-order genomic structure implicated in the mediation of DIP production in bovine coronavirus, with apparent homologs detected in other coronavirus groups. A more in-depth introduction can be found in Alice Huang and David Baltimore's work from 1970.
https://en.wikipedia.org/wiki?curid=451748
1,246,737
1,224,538
Caught in a momentous technological shift, the XB-43 contributed to developing procedures for flying the new jet bombers, and it gave yeoman service testing new turbojet engines. Douglas completed the second prototype, AAF serial number "44-61509", flying on 15 May 1947 and delivered it to Muroc Air Force Base, California, in April 1948. The USAAF soon replaced one J35 turbojet engine with a General Electric J47. Douglas delivered the second prototype, designated YB-43, in April 1948. That aircraft was nicknamed "Versatile II" by USAAF personnel. When the clear plastic nose began to crack from variations in temperature at high and low altitudes, mechanics fashioned a more durable replacement made from plywood. To keep it flying, the US Air Force cannibalized parts from the first XB-43 after it was damaged in February 1951. "Versatile II" flew more than 300 hours until its retirement in December 1953.
https://en.wikipedia.org/wiki?curid=6337344
1,223,878
1,504,609
The development of the fingerprint sensor started during the 1980s by Bo Löfberg. He worked to develop a fingerprint sensor during his last years and later patented the technology before he died in 1986. The sensor was only half way finished at the time of his death but the license was sold to Lennart Carlson who later started his company in 1997, Fingerprint Cards. The company went public in 1998, but still did not have a completed product to sell. On the CeBIT fare in 1999 Ericsson Mobile Communications could showcase a prototype accessory for the Ericsson line of mobile phones that was using a licensed sensor and ASIC from Fingerprint Cards. They also managed to secure licensing deals with Motorola and Texas Instruments, the latter developed an authentication platform known as FADT, the Fingerprint Authentication Development tool based on Fingerprints sensors but using Texas Instruments TMS320 rather than the company's own ASICs for algorithmic processing. Fingerprint Cards made large losses in the developing process and investors had to raise 250 million SEK before the company started produce revenue. Lennart Carlson stepped down as CEO in 2009 and Johan Carlström took over the position from 2009 — 2015.
https://en.wikipedia.org/wiki?curid=60683936
1,503,763
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In the 1960s, Gygax created an organization of wargaming clubs and founded the Gen Con gaming convention. In 1971, he helped develop "Chainmail", a miniatures wargame based on medieval warfare. He co-founded the company Tactical Studies Rules (TSR, Inc.) with childhood friend Don Kaye in 1973. The following year, he and Arneson created "D&D", which expanded on Gygax's "Chainmail" and included elements of the fantasy stories he loved as a child. In the same year, he founded "The Dragon", a magazine based around the new game. In 1977, Gygax began work on a more comprehensive version of the game, called "Advanced Dungeons & Dragons". Gygax designed numerous manuals for the game system, as well as several pre-packaged adventures called "modules" that gave a person running a "D&D" game (the "Dungeon Master") a rough script and ideas on how to run a particular gaming scenario. In 1983, he worked to license the "D&D" product line into the successful "D&D" cartoon series.
https://en.wikipedia.org/wiki?curid=12848
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Paul M. Wood M.D. joined the American Society of Anesthesiologists in 1925 and was made its Secretary-Treasurer in 1929. However in 1932 he became seriously ill and was unable to work, either as a practicing doctor or for the ASA. While convalescing Wood began to catalogue his personal library, which he had been building since he was a medical student, and told ASA founder Dr. Adolph Frederick Erdmann that he wanted to create a museum dedicated to the history of anesthesiology. Erdmann gave him a collection of books and anesthesiology apparatus to add to his own library as the nucleus of the project. In 1933 Wood donated the entire collection to the ASA. The Society asked him to keep it at his home and appointed him librarian and curator for life. They also named the new collection the Wood Library-Museum of Anesthesiology. By 1934 Wood was well enough to return to work. One of the first things he did was to approach Robert H. Ferguson, a retired anesthesiologist whom Erdmann had told him owned the largest collection of specialist books and apparatus in the USA. Ferguson was sympathetic but, still being in good health, preferred to keep his collection at home. Wood turned his attention to the minutes of the Society's meetings, which were now being recorded by a stenographer. As well as discussing ASA business these also contained much information about advances in anesthesiology, and Wood thought they would be a useful resource. He began to make copies and distribute them to the members, and began archiving them in the Library-Museum. In 1938 this system was developed into the ASA's official newsletter.
https://en.wikipedia.org/wiki?curid=39441912
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Schmidt originally dated the site to the PPN based on the types of stone tools found there, considering a PPNA date "most probable". Establishing its absolute chronology took longer due to methodological challenges. Though the first two radiocarbon dates were published in 1998, these and other samples from the of the structure dated to the late 10th and early 9th millennium – 500 to 1000 years later than expected for a PPNA site. Schmidt's team explained the discrepancy in light of their theory that this material was brought to the site from elsewhere when it was abandoned, and so was not representative of the actual use of the structures. They instead turned to a novel method of dating organic material preserved in the plaster on the structure's walls, which resulted in dates more consistent with a PPNA occupation, in the middle or even early 10th-millennium BCE. Subsequent research led to a significant revision of Schmidt's chronology, including the abandonment of the theory that the fill of the structures was brought from elsewhere, and a recognition that direct dates on plaster are affected by the old wood effect. Together with new radiocarbon dates, this has established the site's absolute chronology as falling in the period 9500 to 8000 BCE – the late PPNA and PPNB.
https://en.wikipedia.org/wiki?curid=515395
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He was chief editor of the journal "Perception" for nearly 20 years, and the driving force behind the launch of its open-access sister journal "i-Perception". He was associate editor of ACM Transactions on Applied Perception from 2004 until his death, and was long involved in the Applied Vision Association, becoming its secretary in 2003. A frequent and popular speaker at the European Conference on Visual Perception (ECVP), he and Susan Blackmore organised its 11th meeting in Bristol in 1988. He was renowned for never taking the easy route to conferences but turning each trip into an adventure that might involve cars, trains, skis, his camper van, motorbike, and especially boats. A legacy he left to the Applied Vision Association was used to honour his contributions to vision science and particularly his extraordinary travels, by creating The Tom Trościanko Award to support a student to travel to ECVP in a way that Tom would have enjoyed.
https://en.wikipedia.org/wiki?curid=45218368
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and solves this constraint at the first nontrivial order in the weak-field expansion (note that formula_46 because the free action is gauge invariant). Therefore, the first condition is formula_47. One has to mod out by the trivial solutions that result from nonlinear field redefinitions in the free action. The deformation procedure may not stop at this order and one may have to add quartic terms formula_48 and further corrections formula_49 to the gauge transformations that are quadratic in the fields and so on. The systematic approach is via BV-BRST techniques. Unfortunately, the Noether procedure approach has not given yet any complete example of a higher-spin theory, the difficulties being not only in the technicalities but also in the conceptual understanding of locality in higher-spin theories. Unless locality is imposed one can always find a solution to the Noether procedure (for example, by inverting the kinetic operator in formula_47 that results from the second term) or, the same time, by performing a suitable nonlocal redefinition one can remove any interaction. At present, it seems that higher-spin theories cannot be fully understood as field theories due to quite non-local interactions they have.
https://en.wikipedia.org/wiki?curid=57499209
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The small size of typical 18th century orreries limited their impact, and towards the end of that century a number of educators attempted to create a larger sized version. The efforts of Adam Walker (1730–1821) and his sons are noteworthy in their attempts to fuse theatrical illusions with education. Walker's Eidouranion was the heart of his public lectures or theatrical presentations. Walker's son describes this "Elaborate Machine" as "twenty feet high, and twenty-seven in diameter: it stands vertically before the spectators, and its globes are so large, that they are distinctly seen in the most distant parts of the Theatre. Every Planet and Satellite seems suspended in space, without any support; performing their annual and diurnal revolutions without any apparent cause". Other lecturers promoted their own devices: R E Lloyd advertised his Dioastrodoxon, or Grand Transparent Orrery, and by 1825 William Kitchener was offering his Ouranologia, which was in diameter. These devices most probably sacrificed astronomical accuracy for crowd-pleasing spectacle and sensational and awe-provoking imagery.
https://en.wikipedia.org/wiki?curid=60548
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Indirectly, the effect of gravitational waves had been detected in observations of specific binary stars. Such pairs of stars orbit each other and, as they do so, gradually lose energy by emitting gravitational waves. For ordinary stars like the Sun, this energy loss would be too small to be detectable, but this energy loss was observed in 1974 in a binary pulsar called PSR1913+16. In such a system, one of the orbiting stars is a pulsar. This has two consequences: a pulsar is an extremely dense object known as a neutron star, for which gravitational wave emission is much stronger than for ordinary stars. Also, a pulsar emits a narrow beam of electromagnetic radiation from its magnetic poles. As the pulsar rotates, its beam sweeps over the Earth, where it is seen as a regular series of radio pulses, just as a ship at sea observes regular flashes of light from the rotating light in a lighthouse. This regular pattern of radio pulses functions as a highly accurate "clock". It can be used to time the double star's orbital period, and it reacts sensitively to distortions of spacetime in its immediate neighborhood.
https://en.wikipedia.org/wiki?curid=1411100
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Polkinghorne decided to train for the priesthood in 1977. He said in an interview that he felt he had done his bit for science after 25 years, and that his best mathematical work was probably behind him; Christianity had always been central to his life, so ordination offered an attractive second career. He resigned his chair in 1979 to study at Westcott House, Cambridge, an Anglican theological college, becoming an ordained priest on 6 June 1982 (Trinity Sunday). The ceremony was held at Trinity College, Cambridge, and presided over by Bishop John A. T. Robinson. He worked for five years as a curate in south Bristol, then as vicar in Blean, Kent, before returning to Cambridge in 1986 as dean of chapel at Trinity Hall. He became the president of Queens' College that year, a position he held until his retirement in 1996. He served as canon theologian of Liverpool Cathedral from 1994 to 2005. Polkinghorne died on 9 March 2021 at the age of 90.
https://en.wikipedia.org/wiki?curid=50335
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Mason declined to conduct the work himself for the offered commission of one guinea per day. The task therefore fell to Maskelyne, for which he was granted a temporary leave of his duties as Astronomer Royal. He was aided in the task by mathematician and surveyor Charles Hutton, and Reuben Burrow who was a mathematician of the Royal Greenwich Observatory. A workforce of labourers was engaged to construct observatories for the astronomers and assist in the surveying. The science team was particularly well-equipped: its astronomical instruments included a brass quadrant from Cook's 1769 transit of Venus expedition, a zenith sector, and a regulator (precision pendulum clock) for timing the astronomical observations. They also acquired a theodolite and Gunter's chain for surveying the mountain, and a pair of barometers for measuring altitude. Generous funding for the experiment was available due to underspend on the transit of Venus expedition, which had been turned over to the Society by King George III of the United Kingdom.
https://en.wikipedia.org/wiki?curid=20865567
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Counseling psychology is an applied specialization within psychology, that involves both research and practice in a number of different areas or domains. According to Gelso and Fretz (2001), there are some central unifying themes among counseling psychologists. These include a focus on an individual's strengths, relationships, their educational and career development, as well as a focus on normal personalities. Counseling psychologists help people improve their well-being, reduce and manage stress, and improve overall functioning in their lives. The interventions used by Counseling Psychologists may be either brief or long-term in duration. Often they are problem focused and goal-directed. There is a guiding philosophy which places a value on individual differences and an emphasis on "prevention, development, and adjustment across the life-span." The use of applied psychology in counseling is one of the most useful when it comes to the treatment of individuals. The use of knowledge from scientific findings are beneficial because there are many different options that can be tested to find the right treatment.
https://en.wikipedia.org/wiki?curid=326313
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Technetium-99m ("m" indicates that this is a metastable nuclear isomer) is used in radioactive isotope medical tests. For example, Technetium-99m is a radioactive tracer that medical imaging equipment tracks in the human body. It is well suited to the role because it emits readily detectable 140 keV gamma rays, and its half-life is 6.01 hours (meaning that about 94% of it decays to technetium-99 in 24 hours). The chemistry of technetium allows it to be bound to a variety of biochemical compounds, each of which determines how it is metabolized and deposited in the body, and this single isotope can be used for a multitude of diagnostic tests. More than 50 common radiopharmaceuticals are based on technetium-99m for imaging and functional studies of the brain, heart muscle, thyroid, lungs, liver, gall bladder, kidneys, skeleton, blood, and tumors.
https://en.wikipedia.org/wiki?curid=30041
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New business practices in the areas of management and accounting made possible the more efficient operation of large companies. For example, in steel, coal, and iron companies 19th-century accountants used sophisticated, fully integrated accounting systems to calculate output, yields, and costs to satisfy management information requirements. South Durham Steel and Iron, was a large horizontally integrated company that operated mines, mills, and shipyards. Its management used traditional accounting methods with the goal of minimizing production costs, and thus raising its profitability. By contrast one of its competitors, Cargo Fleet Iron introduced mass production milling techniques through the construction of modern plants. Cargo Fleet set high production goals and developed an innovative but complicated accounting system to measure and report all costs throughout the production process. However, problems in obtaining coal supplies and the failure to meet the firm's production goals forced Cargo Fleet to drop its aggressive system and return to the sort of approach South Durham Steel was using.
https://en.wikipedia.org/wiki?curid=33643110
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Until recently, the medical literature did not indicate a connection among many genetic disorders, both genetic syndromes and genetic diseases, that are now being found to be related. As a result of new genetic research, some of these are, in fact, highly related in their root cause despite the widely varying symptoms apparent on clinical examination. Agenesis of the corpus callosum is one such disease, part of an emerging class of diseases called ciliopathies. The underlying cause may be a dysfunctional molecular mechanism in the primary cilia structures of the cell organelles that are present in many cellular types throughout the human body. The cilia defects adversely affect "numerous critical developmental signaling pathways" essential to cellular development and thus offer a plausible hypothesis for the often multi-symptom nature of a large set of syndromes and diseases. Known ciliopathies include primary ciliary dyskinesia, Bardet–Biedl syndrome, polycystic kidney and liver disease, nephronophthisis, Alström syndrome, Meckel–Gruber syndrome and some forms of retinal degeneration.
https://en.wikipedia.org/wiki?curid=2236023
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The New York State Energy Research and Development Authority (NYSERDA), through its On-Site Wind Turbine Incentive Program (which began in 2007), is making $13.8 million available in incentives to encourage the installation of residential, commercial, institutional, and governmental end-use wind energy systems. The program runs from December 1, 2012 through December 31, 2015, with completed applications accepted through September 30, 2015. NYSERDA will pay up to 50 percent of the total installed cost of the wind energy system to eligible installers who install new approved, grid-connected systems using qualified equipment in accordance with eligibility requirements. The installer must pass the entire incentive through to the customer. The maximum incentive is $1 million per site or customer, and the maximum turbine size is 2 MW (2,000 kW).
https://en.wikipedia.org/wiki?curid=21401237
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At the 2015 workshop, it was argued that software changes required an increment in the model numbering to ACT-R 7.0. A major software change was removal of the requirement that chunks must be specified based on predefined chunk-types.  The chunk-type mechanism was not removed, but changed from being a required construct of the architecture to being an optional syntactic mechanism in the software.  This allowed for more flexibility in knowledge representation for modeling tasks that require learning novel information and extended the functionality provided through dynamic pattern matching now allowing models to create new "types" of chunks.  This also lead to a simplification of the syntax required for specifying the actions in a production because all the actions now have the same syntactic form.  The ACT-R software has also been subsequently updated to include a remote interface based on JSON RPC 1.0.  That interface was added to make it easier to build tasks for models and work with ACT-R from languages other than Lisp, and the tutorial included with the software has been updated to provide Python implementations for all of the example tasks performed by the tutorial models.
https://en.wikipedia.org/wiki?curid=821071
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Most research that defends the idea of fitness programs increasing exercise practices among children and adults stems out of San Diego. Heritage Elementary school implemented its first walking school bus. This initiative had students walking to their designated stops, but not waiting for the school bus. Rather, waiting for a train of people on foot to pick them up. This allowed the students to walk to school with their peers. Although it is not directly stated, a major reason children choose to walk is because they fall victim to mob mentality. Perhaps the phrase, "fall victim to mob mentality" has a negative connotation, but that is, in essence, what the children do. Because so many other students were walking, all joined in. In this instance, mob mentality and mass behavior have a positive influence on fitness behavior, and encourage the students to exercise. The opinion of children, teachers and volunteers has been in general very favorable toward the project. Research states, "91.4 percent of participating students stated they liked the initiative very much and 87.4 percent among them prefer to go to school by the Piedibus than by any other means. Teacher and volunteers outlined the social value of the project and the increase in physical activity as positive aspects of the project". The group environment of the walking bus provides comfort in exercising, which in turn leads children to exercise more often. Although not exactly identical to the "Forrest Gump phenomenon", this walking school bus exhibits the same results: "If I can do it, you can do it".
https://en.wikipedia.org/wiki?curid=3357557
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The quantities sold by the individual manufacturers are likely to be well behind those of their manufactured clarinets with the German system declining, which was probably due to the relatively high prices of these instruments. It was also due to smaller market. Yamaha discontinued production of this type several years ago. The current trend for this system is down (mid-2019). Nevertheless reform Boehm-clarinets are still made by various German manufacturers for lovers of this instrument. Instead of reform Boehm – as already in a work from 2007– "it has recently become increasingly evident that more and more professional clarinettists, in collaboration with instrument makers, are developing individual instruments constructed for the needs of the musicians, based either on the German or the French system." Finally, it should be mentioned that – in accordance with the basic idea of Fritz Wurlitzer – the Canadian manufacter Stephen Fox in recent years has newly developed under acoustic aspects clarinets in B and A, wanting „to blend the focus and cleanness of the German sound with the brilliance and projection of the French clarinet, with superior intonation.“ Their development called in a R13 by Buffet Crampon and a Reform Boehm clarinet by Herbert Wurlitzer, from which some of the above-mentioned mechanisms were taken over and supplemented by others.
https://en.wikipedia.org/wiki?curid=61587617
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The existence of tRNA was first hypothesized by Francis Crick as the "adaptor hypothesis" based on the assumption that there must exist an adapter molecule capable of mediating the translation of the RNA alphabet into the protein alphabet. Paul C Zamecnik and Mahlon Hoagland discovered tRNA Significant research on structure was conducted in the early 1960s by Alex Rich and Donald Caspar, two researchers in Boston, the Jacques Fresco group in Princeton University and a United Kingdom group at King's College London. In 1965, Robert W. Holley of Cornell University reported the primary structure and suggested three secondary structures. tRNA was first crystallized in Madison, Wisconsin, by Robert M. Bock. The cloverleaf structure was ascertained by several other studies in the following years and was finally confirmed using X-ray crystallography studies in 1974. Two independent groups, Kim Sung-Hou working under Alexander Rich and a British group headed by Aaron Klug, published the same crystallography findings within a year.
https://en.wikipedia.org/wiki?curid=532175
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Radio emission from the Sun was first reported in the scientific literature by Grote Reber in 1944. Those were observations of 160 MHz frequency (2 meters wavelength) microwave emission emanating from the chromosphere. However, the earliest known observation was in 1942 during World War II by British radar operators who detected an intense low-frequency solar radio burst; that information was kept secret as potentially useful in evading enemy radar, but was later described in a scientific journal after the war. One of the most significant discoveries from early solar radio astronomers such as Joseph Pawsey was that the Sun produces much more radio emission than expected from standard black body radiation. The explanation for this was proposed by Vitaly Ginzburg in 1946, who suggested that thermal bremsstrahlung emission from a million-degree corona was responsible. The existence of such extraordinarily high temperatures in the corona had previously been indicated by optical spectroscopy observations, but the idea remained controversial until it was later confirmed by the radio data.
https://en.wikipedia.org/wiki?curid=66213716
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The integration of frames, rules, and object-oriented programming was significantly driven by commercial ventures such as KEE and Symbolics spun off from various research projects. At the same time as this was occurring, there was another strain of research that was less commercially focused and was driven by mathematical logic and automated theorem proving. One of the most influential languages in this research was the KL-ONE language of the mid-'80s. KL-ONE was a frame language that had a rigorous semantics, formal definitions for concepts such as an Is-A relation. KL-ONE and languages that were influenced by it such as Loom had an automated reasoning engine that was based on formal logic rather than on IF-THEN rules. This reasoner is called the classifier. A classifier can analyze a set of declarations and infer new assertions, for example, redefine a class to be a subclass or superclass of some other class that wasn't formally specified. In this way the classifier can function as an inference engine, deducing new facts from an existing knowledge base. The classifier can also provide consistency checking on a knowledge base (which in the case of KL-ONE languages is also referred to as an Ontology).
https://en.wikipedia.org/wiki?curid=16920
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The Center for Public Outreach brings the work of the SETI Institute and other leading research organizations, to the general public through its weekly radio broadcast and podcast – "Big Picture Science" and the weekly lecture series "SETI Talks." Big Picture Science is hosted by the institute's Senior Astronomer, Seth Shostak and co-hosted by Executive Producer Molly Bentley. The award-winning general science program engages the public with modern science research through lively and intelligent storytelling and interviews with leading authors, educators and researchers in wide-ranging disciplines. The show mixes engaging and topical science with a dash of humor and proves the thesis that science radio doesn't have to be dull! The institute's weekly colloquium series – SETI Talks, is an in-depth one-hour lecture featuring leading researchers from around the world in astronomy, astrophysics, aerospace technology, astrobiology, machine learning and more. Lectures are free of charge, open to the public and presented at Microsoft's Silicon Valley Campus in Mountain View, California. All SETI Talks are video-taped and archived on YouTube. Over 350 lectures are available on-line, and indexed on the institute's website.
https://en.wikipedia.org/wiki?curid=617552
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In 1947, Strughold was brought to the United States, along with many other highly valuable German scientists, as part of Operation Paperclip. With another former Luftwaffe physician, Richard Lindenberg, Strughold was assigned to the US Air Force School of Aviation Medicine at Randolph Field near San Antonio, Texas. It was while at Randolph Field that Strughold began conducting some of the first research into the potential medical challenges posed by space travel, in conjunction with fellow "Paperclip Scientist" Dr. Heinz Haber. Strughold coined the terms "space medicine" and "astrobiology" to describe this area of study in 1948. The following year he was appointed as the first and only Professor of Space Medicine at the US Air Force's newly established School of Aviation Medicine (SAM), one of the first institutions dedicated to conducting research on "astrobiology" and the so-called "human factors" associated with manned spaceflight. He first described "Mars jars", containers that simulate the atmosphere of Mars, that have now become an essential tool in astrobiological research.
https://en.wikipedia.org/wiki?curid=5204415
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In addition of atypical antipsychotics in cases of inadequate response to antidepressant therapy is an increasingly popular strategy that is well supported in the literature, though these medications may result in greater discontinuation due to adverse events. Aripiprazole was the first drug approved by the US Food and Drug Administration for adjunctive treatment of MDD in adults with inadequate response to antidepressant therapy in the current episode. Recommended doses of aripiprazole range from 2 mg/d to 15 mg/d based on 2 large, multicenter randomized, double-blind, placebo-controlled studies, which were later supported by a third large trial. Most conventional antipsychotics, such as the phenothiazines, work by blocking the D2 Dopamine receptors. Atypical antipsychotics, such as clozapine block both the D2 Dopamine receptors as well as 5HT2A serotonin receptors. Atypical antipsychotics are favored over conventional antipsychotics because they reduce the prevalence of pseudoparkinsonism which causes tremors and muscular rigidity similar to Parkinson’s disease. The most severe side effect of antipsychotics is agranulocytosis, a depression of white blood cell count with unknown cause, and some patients may also experience photosensitivity.
https://en.wikipedia.org/wiki?curid=4786873
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Bonica entered amateur wrestling in high school to pay his way through school and fulfill his dream to go to college. He went on to win championships in the city and state levels. After such a successful high school stint, at age 19, Bonica began to wrestle professionally at carnivals, and continued to do it throughout his years of college at Long Island University and medical school at Marquette University School of Medicine in Milwaukee. He once defeated the entire 36 member wrestling team of an upstate New York college in one day. His monikers included the Masked Marvel and Johnny "Bull" Walker. Bonica wrestled many of the contemporary greats including Jim Londos, Ed "Strangler" Lewis, and had a one-hour draw with Lou Thesz. He won the light heavyweight championship of Canada in 1939. In 1941, Bonica added the NWA World Light Heavyweight Championship to his resume. The years of gladiatorial competition left Dr. Bonica a chronic pain sufferer himself, and thus empathizer with his patients. He would be awarded the Professional Wrestling Hall of Fame New York State Award in 2004.
https://en.wikipedia.org/wiki?curid=35660296
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The biggest technical change in detectors was the development of a tunable induction system. This system involved two coils that are electro-magnetically tuned. One coil act as an RF transmitter the other as a receiver; in some cases these can be tuned to between 3 and 100 kHz. When metal is in their vicinity, a signal is detected owing to eddy currents induced in the metal. What allowed detectors to discriminate between metals was the fact that every metal has a different phase response when exposed to alternating current; longer waves (low frequency) penetrate ground deeper, and select for high conductivity targets like silver, and copper; than shorter waves (higher frequency) which, while less ground penetrating, select for low conductivity targets like iron. Unfortunately, high frequency is also sensitive to ground mineralisation interference. This selectivity or discrimination allowed detectors to be developed that could selectively detect desirable metals, while ignoring undesirable ones.
https://en.wikipedia.org/wiki?curid=165015
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The new submarine project was intended to be an improved version of the , which will be considered obsolete around 2015–2017 according to Per Skantz, development co-ordinator at the Marine headquarters in Stockholm. The submarine would displace 1,900 tonnes and have a crew complement of between 17 and 31 men. The 2008–2010 military budget memorandum to the Minister for Defence by the Supreme Commander Håkan Syrén would require the type to cost no more than the current "Gotland" class (about 1.5 billion SEK). The new submarine would have blue water capability, something earlier Swedish submarines have lacked. It will be equipped with modified AIP stirling propulsion and GHOST (Genuine HOlistic STealth) technology, making the submarine extremely quiet. It will also be designed to withstand significant shock loads from underwater explosions and would be able to "Launch and recover vehicles" through its torpedo tubes. The submarine's sail would largely be composed of the same material that was used when constructing the s.
https://en.wikipedia.org/wiki?curid=15162064
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The final withdrawal of the Mustang from USAF dumped hundreds of P-51s onto the civilian market. The rights to the Mustang design were purchased from North American by the Cavalier Aircraft Corporation, which attempted to market the surplus Mustang aircraft in the U.S. and overseas. In 1967 and again in 1972, the USAF procured batches of remanufactured Mustangs from Cavalier, most of them destined for air forces in South America and Asia that were participating in the Military Assistance Program (MAP). These aircraft were remanufactured from existing original F-51D airframes fitted with new V-1650-7 engines, a new radio, tall F-51H-type vertical tails, and a stronger wing that could carry six machine guns and a total of eight underwing hardpoints. Two bombs and six rockets could be carried. They all had an original F-51D-type canopy but carried a second seat for an observer behind the pilot. One additional Mustang was a two-seat, dual-control TF-51D (67-14866) with an enlarged canopy and only four wing guns. Although these remanufactured Mustangs were intended for sale to South American and Asian nations through the MAP, they were delivered to the USAF with full USAF markings. They were, however, allocated new serial numbers (67-14862/14866, 67-22579/22582 and 72-1526/1541).
https://en.wikipedia.org/wiki?curid=24710
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The CPU for these system ballooned to about a dozen boards because of the low-density ECL chip footprint. As a result, CPUs could only be placed at each end of the SELbus, limiting computer systems to two CPUs. It had modular cache memory that could be upgraded. The ECL circuitry consumed huge amount of current at a very low voltage; the cabinets of the larger models contained extra rack space which held stacks of 400-amp power supplies, and heavy-gauge wiring leading to the backplane. In the mid-1990s, the RSX computer board featured RISC processing capabilities and high speed 75 ns static RAM design (essentially an all-cache design) while maintaining complete binary compatibility with existing programs.
https://en.wikipedia.org/wiki?curid=6766283
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The recruitment of established proteins after the gene duplication leads to play some new biomolecular functions. Among different models that exist, one model suggests that after the gene duplication, among the two copies of genes, one will be subjected to continuous evolution under ancestral dictated functional constraints whereas the duplicate meanwhile will not be restricted by a functional role and feels free to find protein “structure space”. In the end, it may come with encoded new behaviors that which are required for a new physiological function and thereby discourse the selective advantage. In any case, we may consider it as an ambiguous model since most duplicates have to become pseudogenes, which are considered as an inexpressible genetic information (referred to as “junk DNA”) in just a few million years. Because selective pressure can do nothing much with duplicated genes, they are prone to deleterious mutations that present their incapability to encode a protein useful for any function. This restricts to use a functionally unconstrained gene duplicate as a tool for investigating protein structure space of new behaviors that might discourse selectable physiological function. Then how would new functions arise in proteins? One of the possibilities is the resurrection of the pseudogenes due to some biological events like gene conversion. One such an example is the resurrection of the bovine seminal RNase gene.
https://en.wikipedia.org/wiki?curid=35568024
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Using microbes, protocols were developed to insert genes into bacterial plasmids, taking advantage of their fast reproduction, to make biofactories for the gene of interest. Such genetically engineered bacteria can produce pharmaceuticals such as insulin, human growth hormone, interferons and blood clotting factors. These biofactories are typically much cheaper to operate and maintain than the alternative procedures of producing pharmaceuticals. They're like millions of tiny pharmaceutical machines that only require basic raw materials and the right environment to produce a large amount of product. The utilization of incorporating the human insulin gene alone has had profound impacts on the medical industry. It is thought that biofactories might be the ultimate key in reducing the price of expensive life saving pharmaceutical compounds.
https://en.wikipedia.org/wiki?curid=5762008
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In 1904, Christian Hülsmeyer gave public demonstrations in Germany and the Netherlands of the use of radio echoes to detect ships so that collisions could be avoided. His device consisted of a simple spark gap used to generate a signal that was aimed using a dipole antenna with a cylindrical parabolic reflector. When a signal reflected from a ship was picked up by a similar antenna attached to the separate coherer receiver, a bell sounded. During bad weather or fog, the device would be periodically spun to check for nearby ships. The apparatus detected the presence of ships up to , and Hülsmeyer planned to extend its capability to . It did not provide range (distance) information, only warning of a nearby object. He patented the device, called the "telemobiloscope", but due to lack of interest by the naval authorities the invention was not put into production.
https://en.wikipedia.org/wiki?curid=1280053
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Outside of the strategies for physcial and chemical decontamination, advancing research in molecular genetics has also given rise to the potential of a biological decontamination approach. Many microbes, including bacteria, yeast, and fungi, have evolved enzymatic gene products which facilitate the specific and efficient degradation of trichothecene mycotoxins. Many of these enzymes specifically degrade the 12,13 carbon epoxide ring which is important for the toxicity of trichothecenes. For example, the Eubacteria strain BBSH 797 produces de-epoxidase enzymes which reduce the 12,13 carbon epoxide ring to a double bond group. These, along with other microbes expressing trichothecene detoxifying properties, can be used in feed stores to prevent to toxic effect of contaminated feed upon consumption. Furthermore, molecular cloning of the genes responsible for producing these detoxifying enzymes could be useful in producing strains of agricultural products that are resistant to trichothecene poisoning.
https://en.wikipedia.org/wiki?curid=3687230
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In lexicography, the fact that a neologism is used marks its acceptance into the language. This will not be a difficult process so long as each sign has a limited and immediately useful meaning. The problem arises when several possible meanings or shades of meaning become associated with the sign. This is a shift from denotational to connotational meanings. Rules of interpretation are required to resolve uncertainty. Within the community, such rules are, for the most part, experiential and applied without conscious control. Members of a community have a shared memory of language patterns and norms which, for the most part, are stable over long periods of time. Individuals are therefore able to build up a cognitive framework which identifies the possible meanings from any grouping of signs and selects one considered the most appropriate from the context. This intuitive system is continuously tested through the audience's responses. If the responses are satisfying, intuition prevails. If the responses are obviously inappropriate, the audience will consciously review the thought process and decide whether to modify the framework. Semiotics has developed a more precise methodology for this interpretive process, seeking to expose the unstated habitual practices for interpreting signifiers.
https://en.wikipedia.org/wiki?curid=2088106
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In an effort to be more fair and to avoid adding to already high imprisonment rates in the US, courts across America have started using quantitative risk assessment software when trying to make decisions about releasing people on bail and sentencing, which are based on their history and other attributes. It analyzed recidivism risk scores calculated by one of the most commonly used tools, the Northpointe COMPAS system, and looked at outcomes over two years, and found that only 61% of those deemed high risk actually committed additional crimes during that period and that African-American defendants were far more likely to be given high scores that white defendants. These results are part of larger questions being raised in the field of machine ethics with regard to the risks of perpetuating patterns of discrimination via the use of big data and machine learning across many fields.
https://en.wikipedia.org/wiki?curid=23094450
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The concept of a man-machine mixture was widespread in science fiction before World War II. As early as 1843, Edgar Allan Poe described a man with extensive prostheses in the short story "The Man That Was Used Up". In 1911, Jean de La Hire introduced the Nyctalope, a science fiction hero who was perhaps the first literary cyborg, in "Le Mystère des XV" (later translated as "The Nyctalope on Mars"). Nearly two decades later, Edmond Hamilton presented space explorers with a mixture of organic and machine parts in his 1928 novel "The Comet Doom". He later featured the talking, living brain of an old scientist, Simon Wright, floating around in a transparent case, in all the adventures of his famous hero, Captain Future. In 1944, in the short story "No Woman Born", C. L. Moore wrote of Deirdre, a dancer, whose body was burned completely and whose brain was placed in a faceless but beautiful and supple mechanical body.
https://en.wikipedia.org/wiki?curid=20756967
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The Enrico Fermi Nuclear Generating Station is a nuclear power plant on the shore of Lake Erie near Monroe, in Frenchtown Charter Township, Michigan on approximately . All units of the plant are operated by the DTE Energy Electric Company and owned (100 percent) by parent company DTE Energy. It is approximately halfway between Detroit, Michigan, and Toledo, Ohio. It is also visible from parts of Amherstburg and Colchester, Ontario as well as on the shore of Lake Erie in Ottawa County, Ohio. Two units have been constructed on this site. The first unit's construction started on August 4, 1956 and reached initial criticality on August 23, 1963, and the second unit received its construction permit on September 26, 1972. It reached criticality (head on) on June 21, 1985 and was declared commercial on November 18, 1988. The plant is connected to two single-circuit 345 kV Transmission Lines and three 120 kV lines. They are operated and maintained by ITC Transmission.
https://en.wikipedia.org/wiki?curid=1835482
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Due to the relatively shallow water, the rock that was vaporized included sulfur-rich gypsum from the lower part of the Cretaceous sequence, and this was injected into the atmosphere. This global dispersal of dust and sulfates would have led to a sudden and catastrophic effect on the climate worldwide, instigating large temperature drops and devastating the food chain. The researchers stated that the impact generated an environmental calamity that extinguished life, but it also induced a vast subsurface hydrothermal system that became an oasis for the recovery of life. Researchers using seismic images of the crater in 2008 determined that the impactor landed in deeper water than previously assumed, which may have resulted in increased sulfate aerosols in the atmosphere, due to more water vapor being available to react with the vaporized anhydrite. This could have made the impact even deadlier by cooling the climate and generating acid rain.
https://en.wikipedia.org/wiki?curid=174609
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As organisms age and cells proliferate, telomeres shorten with each round of replication. Cells restricted to a specific lineage are capable of division only a set number of times, set by the length of telomeres, before they senesce. Depletion and uncapping of telomeres has been linked to organ degeneration, failure, and fibrosis due to progenitors' becoming quiescent and unable to differentiate. Using an "in vivo" TERT deficient mouse model, reactivation of the TERT gene in quiescent populations in multiple organs reactivated telomerase and restored the cells’ abilities to differentiate. Reactivation of TERT down-regulates DNA damage signals associated with cellular mitotic checkpoints allowing for proliferation and elimination of a degenerative phenotype. In another study, introducing the TERT gene into healthy one-year-old mice using an engineered adeno-associated virus led to a 24% increase in lifespan, without any increase in cancer.
https://en.wikipedia.org/wiki?curid=12303321
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Most protein pharmaceuticals are now produced through recombinant DNA technology using expression vectors. These peptide and protein pharmaceuticals may be hormones, vaccines, antibiotics, antibodies, and enzymes. The first human recombinant protein used for disease management, insulin, was introduced in 1982. Biotechnology allows these peptide and protein pharmaceuticals, some of which were previously rare or difficult to obtain, to be produced in large quantity. It also reduces the risks of contaminants such as host viruses, toxins and prions. Examples from the past include prion contamination in growth hormone extracted from pituitary glands harvested from human cadavers, which caused Creutzfeldt–Jakob disease in patients receiving treatment for dwarfism, and viral contaminants in clotting factor VIII isolated from human blood that resulted in the transmission of viral diseases such as hepatitis and AIDS. Such risk is reduced or removed completely when the proteins are produced in non-human host cells.
https://en.wikipedia.org/wiki?curid=564380
824,214
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Methanol and dimethyformamide extracts of "Halimeda opuntia" have been observed to have antibacterial properties against some species of microorganisms, including "Saccharomyces cerevisiae", "Escherichia coli", "Bacillus subtilis", and most significantly, "Staphylococcus" "aureus." "Halimeda" opuntia ethanol extract exhibited activity against hepatitis C virus (HCV) due to polymerase inhibitory (HCV-796) binding sites based on molecular docking simulation. Methanolic extracts of "Halimeda macroloba" have recently been found to exhibit cytotoxicity towards MCF-7 and HT 29 cells, which are derived from human breast cancer cell lines and colon cancer lines, respectively. These results therefore suggest the genus' potential for cultivation as a food source. An experiment on rats showed that free phenolic acids of "Halimeda monile" have antioxidant properties which could aid in protecting against liver problems. "Halimeda tuna" appears to be used as fodder in the Philippines.
https://en.wikipedia.org/wiki?curid=2542150
1,155,517
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The lower 6 of the 8 water-cooled models (codenamed H0) were immediately available, but used the same processor as the 3090-J, still at the 69 MHz (14.5 ns) maximum frequency and thus with unchanged performance. Those models' main difference from the 3090-J was the optional addition of ESCON, Sysplex and Integrated Cryptographic Feature. Only the models 900 and 820 had an all-new design (codenamed H2), featuring private split I+D 128+128 KB L1 caches and a shared 4 MB L2 cache (2 MB per side) with 11-cycle latency, more direct interconnects between the processors, multi-level TLBs, branch target buffer and 111 MHz (9 ns) clock frequency. These were the first models with out-of-order execution since the System/370-195 of 1973. However unlike the old S/360-91-derived systems, the models 900 and 820 had full out-of-order execution for both integer and floating-point units, with precise exception handling, and a fully superscalar pipeline. Models 820 and 900 shipped to customers in September 1991, a year later than the models with older technology. Later these new technologies were used in models 520, 640, 660, 740 and 860.
https://en.wikipedia.org/wiki?curid=53030665
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Stuart Sumida, writing in "The Quarterly Review of Biology," stated that "The authors make a valiant attempt to clear locality and phylogenetic perspectives, but it is a mixed bag. They are properly up to date on the theropod origin of feathers and birds, yet they are a quarter century behind on mammalian ancestors, still calling them mammal-like reptiles as opposed to Synapsida." He also noted that "a survey of colleagues generated a list of errors in virtually every section of the book" but concluded that the book is "a visual tour de force, confirming that computer generated (CG)-based reconstructions have justifiably joined the more traditional disciplines of sculpture, drawing, and painting in paleobiological art. In the end, it is visually impressive, but its textual potential remains unrealized."
https://en.wikipedia.org/wiki?curid=9080865
1,570,161
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Regression-kriging-based algorithms play more and more important role in geostatistics because the number of possible covariates is increasing every day. For example, DEMs are now available from a number of sources. Detailed and accurate images of topography can now be ordered from remote sensing systems such as SPOT and ASTER; SPOT5 offers the High Resolution Stereoscopic (HRS) scanner, which can be used to produce DEMs at resolutions of up to 5 m. Finer differences in elevation can also be obtained with airborne laser-scanners. The cost of data is either free or dropping in price as technology advances. NASA recorded most of the world's topography in the Shuttle Radar Topographic Mission in 2000. From summer of 2004, these data has been available (e.g. via USGS ftp) for almost whole globe at resolution of about 90 m (for the North American continent at resolution of about 30 m). Likewise, MODIS multispectral images are freely available for download at resolutions of 250 m. A large free repository of Landsat images is also available for download via the Global Land Cover Facility (GLCF).
https://en.wikipedia.org/wiki?curid=36213065
1,690,396
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Nitrocellulose lacquer manufactured by (among others) DuPont, was the primary material for painting automobiles for many years. Durability of finish, complexities of "multiple stage" modern finishes, and other factors including environmental regulation led manufacturers to choose newer technologies. It remained the favorite of hobbyists for both historical reasons and for the ease with which a professional finish can be obtained. Most automobile "touch up" paints are still made from lacquer because of its fast dying, easy application, and superior adhesion properties – regardless of the material used for the original finish. Guitars sometimes shared color codes with current automobiles. It fell out of favor for mass production use for a number of reasons including environmental regulation and the cost of application vs. "poly" finishes. However, both Fender and Gibson still use nitrocellulose lacquers in their "Custom" shops when reproducing historically accurate guitars. The nitrocellulose lacquer yellows and cracks over time, and custom shops will reproduce this aging to make instruments appear vintage. Guitars made by smaller shops (luthiers) also often use "nitro" as it has an almost mythical status among guitarists.
https://en.wikipedia.org/wiki?curid=58246
383,151
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Mims has no formal academic training in science, but still went on to have a successful career as a science author, researcher, lecturer and syndicated columnist. His series of hand-lettered and illustrated electronics books sold over 7.5 million copies and he is widely regarded as one of the world's most prolific citizen scientists. Mims does scientific studies in many fields using instruments he designs and makes and his scientific papers have been published in many peer-reviewed journals, often with professional scientists as co-authors. Much of his research deals with ecology, atmospheric science and environmental science. A simple instrument he developed to measure the ozone layer earned him a Rolex Award for Enterprise in 1993. In December 2008, "Discover" named Mims one of the "50 Best Brains in Science."
https://en.wikipedia.org/wiki?curid=1527744
1,125,642
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BCOs will still analyze and synthesize scientific and technical information (STI). However, they also are to take on an expanded role in program analysis and integration by assessing and shaping nearly $6 billion in Technical Area Tasks (TATs). TATs are a companion offering of the IAC Program, by which DTIC leverages industry and academia's best and brightest to conduct research and analysis, developing innovative solutions to the most challenging requirements. IAC BCOs will ensure consistency with and reduce duplication of prior or other ongoing work and by helping to ensure TATs are more responsive both to customer needs and broader DoD imperatives. BCOs also are to ensure that TAT results are properly documented and made available for broad dissemination. This approach both achieves cost savings and reduces risks, ensuring that in this time of shrinking budgets and evolving requirements, the Defense community leverages all available knowledge to identify and implement innovative solutions.
https://en.wikipedia.org/wiki?curid=40326059
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However, when a large enough electric field is applied to any insulating substance, at a certain field strength the number of charge carriers in the material suddenly increases by many orders of magnitude, so its resistance drops and it becomes a conductor. This is called "electrical breakdown". The physical mechanism causing breakdown differs in different substances. In a solid, it usually occurs when the electric field becomes strong enough to pull outer valence electrons away from their atoms, so they become mobile, and the heat created by their collisions with other atoms releases additional electrons. In a gas, the electric field accelerates the small number of free electrons naturally present (due to processes like photoionization and radioactive decay) to a high enough speed that when they collide with gas molecules they knock additional electrons out of them, called ionization, which go on to ionize more molecules creating more free electrons and ions in a chain reaction called a Townsend discharge. As these examples indicate, in most materials breakdown occurs by a rapid chain reaction in which mobile charged particles release additional charged particles.
https://en.wikipedia.org/wiki?curid=853826
981,219
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The onset of veraison does not occur uniformly among all berries. Typically the berries and clusters that are most exposed to warmth, on the outer extents of the canopy, undergo veraison first with the berries and clusters closer to the trunk and under the canopy shade undergoing it last. There are some factors in the vineyards that can control the onset of veraison, limited water stress and canopy management that creates a high "fruit to leaf" ratio can encourage veraison. This is because the vine is biologically programmed to channel all its energies and resources into the berries, which houses its seedling offspring, to provide them a better chance of survival. Conversely, very vigorous vines with plentiful leaf shading for photosynthesis and water supply will delay the start of veraison due to the vines energies being directed towards continued shoot growth of new buds. For the production of high-quality wine, it is considered ideal to have an earlier veraison. During this period the cane of the vine starts to ripen as well changing from green and springing to brown and hard. The vines begins to divert some of its energy production into its reserves in preparation for its next growth cycle.
https://en.wikipedia.org/wiki?curid=19533906
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"Jupiter" was converted into the first US aircraft carrier at the Norfolk Naval Shipyard, Portsmouth, Virginia. On 11 April 1920, she was renamed "Langley" in honor of Samuel Pierpont Langley, an American astronomer, physicist, aeronautics pioneer and aircraft engineer, and she was given the hull number "CV-1". By early 1921, memories of World War I were swaying public opinion away from warship construction toward disarmament. Article VIII of the Washington Naval Treaty provided an exemption for experimental aircraft carriers in existence or building on 12 November 1921. The Washington Naval Treaty was signed on 6 February 1922; and "Langley" was recommissioned on 20 March 1922 for the purpose of conducting experiments in seaborne aviation. The commanding officer was Commander Kenneth Whiting, who had first proposed conversion of a collier to the General Board of the United States Navy three years and twelve days earlier.
https://en.wikipedia.org/wiki?curid=199421
279,687
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The race started at 11:30 a.m. on 7 August 2012. Richard Varga led early in the swim and held the lead to come out of the water first. His swim leg split time was 16minutes and 56seconds, fourseconds faster than Javier Gómez and those two; along with both of the Brownlees, Ivan Vasiliev and Alessandro Fabian; formed a lead group of six that had an 11second gap over the rest of the field. At the transition between the running and cycling legs, Jonathan Brownlee was given a 15second penalty for riding his bike before the transition zone. On the ride the race reformed with a 22-man strong group together for the majority of the discipline. Alistair Brownlee, aware of both his superiority in the run leg and the penalty facing his brother, put the hammer down from the very beginning of the run, aiming to crack the rest of the field and create a gap for himself and his brother. The senior Brownlee soon started to run away from the rest of the field with only his brother and Gómez attempting to follow him. Jonathan Brownlee was dropped from the group at approximately halfway through the run and then Alistair Brownlee dropped Gómez with to go. Alistair Brownlee would go on to win the race in a time of onehour, 46minutes and 25seconds, beating Gómez by 11seconds. Despite having to serve his time penalty at the end of the second-last running lap, the brutal speed of the group of three worked as Jonathan Brownlee held on to the bronze medal position, 20seconds behind Gómez but 18seconds in front of fourth-placed David Hauss of France.
https://en.wikipedia.org/wiki?curid=36513641
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Researchers from the University of Twente, the University of Patras in Greece, and the Foundation for Fundamental Research on Matter have constructed a Feynman–Smoluchowski engine which, when not in thermal equilibrium, converts pseudo-Brownian motion into work by means of a granular gas, which is a conglomeration of solid particles vibrated with such vigour that the system assumes a gas-like state. The constructed engine consisted of four vanes which were allowed to rotate freely in a vibrofluidized granular gas. Because the ratchet's gear and pawl mechanism, as described above, permitted the axle to rotate only in one direction, random collisions with the moving beads caused the vane to rotate. This seems to contradict Feynman's hypothesis. However, this system is not in perfect thermal equilibrium: energy is constantly being supplied to maintain the fluid motion of the beads. Vigorous vibrations on top of a shaking device mimic the nature of a molecular gas. Unlike an ideal gas, though, in which tiny particles move constantly, stopping the shaking would simply cause the beads to drop. In the experiment, this necessary out-of-equilibrium environment was thus maintained. Work was not immediately being done, though; the ratchet effect only commenced beyond a critical shaking strength. For very strong shaking, the vanes of the paddle wheel interacted with the gas, forming a convection roll, sustaining their rotation.
https://en.wikipedia.org/wiki?curid=432276
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The Keynesian aggregate supply curve shows that the AS curve is significantly horizontal implying that the firm will supply whatever amount of goods is demanded at a particular price level during an economic depression. The idea behind that is because there is unemployment, firms can readily obtain as much labour as they want at that current wage and production can increase without any additional costs (e.g. machines are idle which can simply be turned on). Firms' average costs of production therefore are assumed not to change as their output level changes. This provides a rationale for Keynesians' support for government intervention. The total output of an economy can decline without the price level declining; this fact, in conjunction with the Keynesian belief of wages being inflexible downwards, clarifies the need for government stimulus. Since wages cannot readily adjust low enough for aggregate supply to shift outward and improve total output, the government must intervene to accomplish this result. However, the Keynesian aggregate supply curve also contains a normally upward-sloping region where aggregate supply responds accordingly to changes in price level. The upward slope is due to the law of diminishing returns as firms increase output, which states that it will become marginally more expensive to accomplish the same level of improvement in productive capacity as firms grow. It is also due to the scarcity of natural resources, the rarity of which causes increased production to also become more expensive. The vertical section of the Keynesian curve corresponds to the physical limit of the economy, where it is impossible to increase output.
https://en.wikipedia.org/wiki?curid=14425627
990,954
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An alternative to using bounding box-based rigid body physics systems is to use a finite element-based system. In such a system, a 3-dimensional, volumetric tessellation is created of the 3D object. The tessellation results in a number of finite elements which represent aspects of the object's physical properties such as toughness, plasticity, and volume preservation. Once constructed, the finite elements are used by a solver to model the stress within the 3D object. The stress can be used to drive fracture, deformation and other physical effects with a high degree of realism and uniqueness. As the number of modeled elements is increased, the engine's ability to model physical behavior increases. The visual representation of the 3D object is altered by the finite element system through the use of a deformation shader run on the CPU or GPU. Finite Element-based systems had been impractical for use in games due to the performance overhead and the lack of tools to create finite element representations out of 3D art objects. With higher performance processors and tools to rapidly create the volumetric tessellations, real-time finite element systems began to be used in games, beginning with "" that used Digital Molecular Matter for the deformation and destruction effects of wood, steel, flesh and plants using an algorithm developed by Dr. James O'Brien as a part of his PhD thesis.
https://en.wikipedia.org/wiki?curid=1453385
793,995
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The physiological-trait-based breeding approach has merit over breeding for yield "per se" because it increases the probability of crosses resulting in additive gene action. The concept of combination phenomics comes from the idea that two or more stress have common physiological effect or common traits - which is an indicator of overall plant health. Similar analogy in human medical terms is high blood pressure or high body temperature or high white blood cells in body is an indicator of health problems and thus we can select healthy people from unhealthy using such a measure. As both abiotic and abiotic stresses can result in similar physiological consequence, tolerant plant can be separated from sensitive plants. Some imaging or infrared measuring techniques can help to speed the process for breeding process. For example, spot blotch intensity and canopy temperature depression can be monitored with canopy temperature depression.
https://en.wikipedia.org/wiki?curid=34172227
1,921,416
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While many joint locks are permitted in BJJ, most competitions ban or restrict some or all joint locks that involve the knees, ankles, and spine. The reason for this is that the angles of manipulation required to cause pain are nearly the same as those that would cause serious injury. Joint locks that require a twisting motion of the knee (such as heel hooks or knee bars) are usually banned in competitions because successfully completing the move can frequently result in permanent damage, often requiring surgery. Similarly, joint manipulations of the spine are typically barred due to the inherent danger of crushing or misaligning cervical vertebrae. Leglocks are allowed in varying degrees depending on skill level, with the most prominent BJJ tournaments typically allowing only the straight ankle lock and muscle stretching submissions such as the "banana split" from white through purple belt, with the kneebar, toehold, and calf slicer submissions being permitted at brown and black belt. Heel hooks and knee-reaping are illegal in gi BJJ, since they are considered to be exceptionally dangerous techniques, but are allowed by IBJJF rules in no-gi competitions. Most joint locks involving the wrist, elbow, shoulder or ankle are permitted as there is a great deal more flexibility in those joints and those locks are usually safe.
https://en.wikipedia.org/wiki?curid=207083
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Engines considered for the Piranha were the Volkswagen air-cooled engine and a water-cooled automobile V6 engine from Chevrolet. The engine finally chosen was an aluminum block Chevrolet small-block V8 developing an estimated . The Piranha came equipped with a ballistically deployed parachute capable of lowering pilot and aircraft together safely to the ground. The tub was reinforced with Kevlar to protect the pilot from light arms fire. The aircraft provided up to four hard points for mounting armaments and ordnance, including a McDonnell Douglas/Boeing (MDHC) M230LF 30 mm cannon, M60 type 7.62 mm machine guns, 7-shot rocket launching pods for 70 mm MK66, MK4 or MK40 rockets, LAU-32 rocket pods, MK81 general purpose low-drag bombs, MK122 Fireye fire bombs, an SUU-11 7.62 mm minigun pod, or an XM13 grenade launcher. The Piranha weighed and had a vertical climb rate of greater than 4000 fpm (20.32 m/s).
https://en.wikipedia.org/wiki?curid=68222537
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In a case study conducted by Rivera (2012) for hiring new employees in elite professional service firms, there was evidence that showed that similarity attributes were considered by the hiring managers and committee during the hiring process. After passing the initial interview requirements, employers would seek out candidates who not only meet the technical requirements of the job (for example, educational or relevant work experience), but would also pick potential employees who appear like themselves in areas such as experiences, academic achievements, leisure pursuits, and self-presentation styles. These attributes that were discovered were done during the discussion phase of the interview and would often be the greatest factor in whether a potential employee would be hired, even more so than the credentials on their resume. The most notable reason for this was due to the nature of the businesses being elite service firms that are client focused. Employers preferred to hire employees they could trust, as it was considered more important than technical skills, which employers believed could be trained into new hires over time.
https://en.wikipedia.org/wiki?curid=44480752
1,907,711
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The focus of the Center's mission and vision for the future is to continue its international, national and regional leadership in wildlife research. The Center will enhance its accomplishments in generating, interpreting, evaluating, and transmitting the scientific information needed to address better the pressing problems of managing the United States' biological resources, especially those under the stewardship of the Department of the Interior, as well as other Federal and non-Federal partners. Today's challenges in natural resource management involve new approaches such as adaptive management, landscape and ecosystem scale management, partnerships among multiple stakeholders, and transfer and use of the vast store of existing information using modern technology.
https://en.wikipedia.org/wiki?curid=2349086
1,587,421
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RuleML is a global initiative, led by a non-profit organization RuleML Inc., that is devoted to advancing research and industry standards design activities in the technical area of rules that are semantic and highly inter-operable. The standards design takes the form primarily of a markup language, also known as RuleML. The research activities include an annual research conference, the RuleML Symposium, also known as RuleML for short. Founded in fall 2000 by Harold Boley, Benjamin Grosof, and Said Tabet, RuleML was originally devoted purely to standards design, but then quickly branched out into the related activities of coordinating research and organizing an annual research conference starting in 2002. The "M" in "RuleML" is sometimes interpreted as standing for "Markup and Modeling". The markup language was developed to express both forward (bottom-up) and backward (top-down) rules in XML for deduction, rewriting, and further inferential-transformational tasks. It is defined by the Rule Markup Initiative, an open network of individuals and groups from both industry and academia that was formed to develop a canonical Web language for rules using XML markup and transformations from and to other rule standards/systems.
https://en.wikipedia.org/wiki?curid=1568414
1,610,057
1,975,692
The first release of the OSGi Residential Specification resolved the requirements of inter-operation with existing management systems and protocols, the need to remotely manage user applications life cycle as well as the need for large-scale deployments and adequate security. With this second release of the OSGi Residential Specification we introduce new specifications for abstracting devices, sensors, actuators, etc. from their corresponding communication protocols and facilitate the development of new innovative application and services. This release also contains specifications that address device connectivity via the EnOcean wireless protocol, USB and serial port. With the Resource Monitoring Specification, resources consumed by bundles can be monitored in order to fairly share resources and preserve the overall quality of service. The Network Interface Information Service Specification enables dynamic discovery of changes in the network interface.
https://en.wikipedia.org/wiki?curid=27362477
1,974,555
1,828,750
While the same analytical approaches used for profiling metabolites apply to exometabolomics, including liquid-chromatography mass spectrometry (LC-MS), nuclear magnetic resonance (NMR) and gas chromatography–mass spectrometry (GC–MS), analysis of exometabolites provides specific challenges and is most commonly focused on investigation of the transformations of exogenous metabolite pools by biological systems. Typically, these experiments are performed by comparing metabolites at two or more time points, for example, spent vs. uninoculated/control culture media; this approach can differentiate different physiological states of wild-type yeast and between yeast mutants. Since, in many cases, the exometabolite (extracellular) pool is less dynamic than endometabolite (intracellular) pools (which are often perturbed during sample processing) and chemically defined media can be used, it reduces some of the experimental challenges of metabolomics.
https://en.wikipedia.org/wiki?curid=48745491
1,827,710
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Cytotoxic T cells have been implicated in the progression of arthritis. The main involvement of rheumatoid arthritis is its joint involvement, the synovial membrane is characterised by hyperplasia, increased vascularity and infiltrate of inflammatory cells, mainly CD4+ T lymphocytes, which are the main organiser of cell-mediated immune responses. In different studies, rheumatoid arthritis is strongly linked to major histocompatibility complex (MHC) class II antigens. The only cells in the body that express MHC class II antigens are constitutive antigen-presenting cells. This strongly suggests that rheumatoid arthritis is caused by unidentified arthritogenic antigens. The antigen could be any exogenous antigen, such as viral proteins, or an endogenous protein. Recently, a number of possible endogenous antigens have been identified, for example, human cartilage glycoprotein 39, heavy chain binding protein and citrullinated protein. Activated CD4+ T lymphocytes stimulate monocytes, macrophages and synovial fibroblasts to elaborate the cytokines interleukin-1, interleukin-6 and tumour necrosis factor alpha (TNFa), and to secrete metalloproteinases. The first three of which are key in driving inflammation in rheumatoid arthritis. These activated lymphocytes also stimulate B cells to produce immunoglobulins, including rheumatoid factor. Their pathogenic role is unknown, but may be due to complement activation through immune complex formation. Moreover, several animal studies suggest that cytotoxic T cells may have a predominantly proinflammatory effect in the disease. It is also studied that the production of cytokines by the CD8+ cells may accelerate the progresses of the arthritis disease.
https://en.wikipedia.org/wiki?curid=211947
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Another major result of network convergence included the approval of mergers and acquisitions. Mergers and acquisitions are a couple of ways to enter a new market and further propelled companies to enter into strategic alliances, joint ventures, and in some cases, mergers, which enables them to offer a menu of product options to customers and to operate their systems more efficiently. Digital convergence encourages mergers between companies in different areas and changes the service market. In 1998, FCC reviewed the applications of the MCI–WorldCom, SBC–SNET, AT&T–Teleport and AT&T–TCI mergers. FCC also took time to review petitions by SBC, which wanted to extend the time the Commission determined for it to comply with the conditions of its merger with Ameritech. Mergers reviewed in 2000 included Bell Atlantic–GTE, which became;jter approval; Qwest–US West; and MCI WorldCom–Sprint, which was withdrawn; Verizon–NorthPoint; and Verizon–One Point. Carriers are adding services to their traditional telephone business after upgrading their networks and engaging in multiple alliances and acquisitions of other companies. Additionally, companies that already offer a substantial number of these services have been able to charge comparatively lower fees to having these services provided by different companies.
https://en.wikipedia.org/wiki?curid=31591629
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Experimentally, the (C→A) and (B→A) lines overlap, producing a continuum centered at 345 nm, often of low amplitude as can be observed in Figure 11. The width of the emission depends on the transition tending to a strongly repulsive state. Koltz "et al." placed this continuum at between 312 and 460 nm. The weak observed intensities are attributed to the weakness of the probabilities of the transition of the two emissions opposite that of the B→X and by the small amounts of states C formed with respect to states B as was previously seen. Other authors have called attention to the absorption phenomena of molecule at this wavelength. According to Kannari "et al.", reaction (3) is the principal pathway for synthesis of states B and C. Tsuji "et al." estimated the proportions of states B and C formed: 38% for state C and 62% state B. The value of the transition probabilities (theoretical value of I/I = 0.07; experimental value of 0.05), so the contribution of (B→A) emission is about 10%. Several authors claimed that a laser based on the 345 nm emission could be developed, especially at pressures of about 10 atmospheres when states B and C are thermalized. Meanwhile, no concrete result had been discovered as of 2014.
https://en.wikipedia.org/wiki?curid=36182278
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Within a month of his arrival back in England, Carton de Wiart was summoned to spend a night at the prime minister's country home at Chequers. Churchill informed him that he was to be sent to China as his personal representative. He was granted the rank of acting lieutenant-general on 9 October, and left by air for India on 18 October 1943. Anglo-Chinese relations were difficult in World War II as the Kuomintang had long called for the end of British extraterritorial rights in China together with the return of Hong Kong, neither proposal being welcome to Churchill. In early 1942, Churchill had to ask Chiang Kai-shek to send Chinese troops to help the British hold Burma from the Japanese, and following the Japanese conquest of Burma the X Force of five Chinese divisions had ended up in eastern India. Churchill was unhappy with having the X Force defend India as it weakened the prestige of the Raj, and in an attempt to improve relations with China, the prime minister felt a soldier with experience of diplomacy such as Carton de Wiart would be the best man to be his personal representative in China.
https://en.wikipedia.org/wiki?curid=1194551
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Between 1810 and 1910, almost 400 medical schools were opened, however none were yet associated with local hospitals. However, many of them were inferior to those created by the University of Pennsylvania in 1874 and Lakeside Hospital in Cleveland in 1898. This is in part due to publishing of the Flexner Report which revealed the weaknesses of the United States current system for clinical teaching. Of the 400 medical schools established, the majority did not have control of hospital facilities, such as wards, to be used for teaching and research. As a result, these institutions could not adapt at clinical curriculum of learning by doing, which the Flexner Report supported as the most effective method of clinical education. Additionally, many states mandated all physician to earn a state license of practice. By 1895, every state was obliged to create a board of medical examiners to design and administer standardized state examinations in a range of topics from those mainly in medicine to pathology and pharmacology. The introduction of state examinations reduced the number of medical students practicing. The increasing requirements for medical schools and future practitioners led to the immediate closure of many medical schools in the United States.
https://en.wikipedia.org/wiki?curid=485700
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Eigen made several assumptions about conditions that led to the formation of the first hypercycles. Some of them were the consequence of the lack of knowledge about ribozymes, which were discovered a few years after the introduction of the hypercycle concept and negated Eigen's assumptions in the strict sense. The primary of them was that the formation of hypercycles had required the availability of both types of chains: nucleic acids forming a quasispecies population and proteins with enzymatic functions. Nowadays, taking into account the knowledge about ribozymes, it may be possible that a hypercycle's members were selected from the quasispecies population and the enzymatic function was performed by RNA. According to the hypercycle theory, the first primitive polymerase emerged precisely from this population. As a consequence, the catalysed replication could exceed the uncatalysed reactions, and the system could grow faster. However, this rapid growth was a threat to the emerging system, as the whole system could lose control over the relative amount of the RNAs with enzymatic function. The system required more reliable control of its constituents—for example, by incorporating the coupling of essential RNAs into a positive feedback loop. Without this feedback loop, the replicating system would be lost. These positive feedback loops formed the first hypercycles.
https://en.wikipedia.org/wiki?curid=29491519
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Although there was a Spanish royal decree that was issued on May 31, 1828, assigning that there should be one veterinarian for the Philippine islands (a number later increased to two veterinarians in 1843), the highlight of the history of veterinary medicine in the Philippines was in 1888, when the need to investigate the occurrence of the rinderpest epizootic (cattle plague) in the Philippine islands emerged. The cattle plague that affected the cow and carabao (water buffalo) population between Manila and Bulacan were caused by sick animals that were imported from Indochina and Hong Kong. The Commission assigned to perform the investigation was appointed by Don Benigno Quiroga y Ballesteros, the Director General of the Administración Civil de Filipinas (Civil Administration of the Philippines) during that time. The Commission was composed of an army veterinarian, a pharmacist, and a medical doctor. The army veterinarian and head of the Commission was Don Gines Geis y Gotzens. The pharmacist was Don Anacleto del Rosario y Sales, who at the time was the Director of the Laboratorio Municipal de Manila (Municipal Laboratory of Manila). The physician was Don Francisco Masip, an official in-charge of public health. The 1888 cattle plague (also known as steppe murrain) prompted the need for the services of veterinarians in the Philippines, including those from the ranks (commissioned officers) of the Spanish Army. The effects of the plague lasted from 1888 through 1939, meaning it moved on from Spanish period up to the American period in the history of the Philippines. From 1901 to 1902 alone, more than 600,000 cattle and water buffaloes were killed by the disease.
https://en.wikipedia.org/wiki?curid=41230641
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Smith Hall was named after David Eugene Smith, who headed the school from 1898 to 1901. He succeeded McLean as president, having been selected from a long list of possible candidates. He was born and raised in Cortland, New York and received his Doctorate of Philosophy degree at Syracuse University in 1887. He wanted to establish a close working relationship between the alumni, faculty and students. Dr. Smith studied law in his father's office and was admitted to the bar in 1884. He chose to be a professor of mathematics at Ypsilanti instead. Dr. Smith produced 500 publications, including over 50 textbooks. He arrived in Brockport in 1898 and stayed until 1901. Smith pushed for the expansion of the practice school and fought many a battle with the state over what he saw as inadequate funding. Frustrated by the lack of state support, he left to take a position at Columbia.
https://en.wikipedia.org/wiki?curid=512315
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"Complexity in ecology is of at least six distinct types: spatial, temporal, structural, process, behavioral, and geometric." From these principles, ecologists have identified emergent and self-organizing phenomena that operate at different environmental scales of influence, ranging from molecular to planetary, and these require different explanations at each integrative level. Ecological complexity relates to the dynamic resilience of ecosystems that transition to multiple shifting steady-states directed by random fluctuations of history. Long-term ecological studies provide important track records to better understand the complexity and resilience of ecosystems over longer temporal and broader spatial scales. These studies are managed by the International Long Term Ecological Network (LTER). The longest experiment in existence is the Park Grass Experiment, which was initiated in 1856. Another example is the Hubbard Brook study, which has been in operation since 1960.
https://en.wikipedia.org/wiki?curid=9630
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Towards the late 18th century, Mathurin Jacques Brisson (1723–1806) and Comte de Buffon (1707–1788) began new works on birds. Brisson produced a six-volume work "Ornithologie" in 1760 and Buffon's included nine volumes (volumes 16–24) on birds "Histoire naturelle des oiseaux" (1770–1785) in his work on science "Histoire naturelle générale et particulière" (1749–1804). Jacob Temminck sponsored François Le Vaillant [1753–1824] to collect bird specimens in Southern Africa and Le Vaillant's six-volume "Histoire naturelle des oiseaux d'Afrique" (1796–1808) included many non-African birds. His other bird books produced in collaboration with the artist Barraband are considered among the most valuable illustrated guides ever produced. Louis Jean Pierre Vieillot (1748–1831) spent 10 years studying North American birds and wrote the "Histoire naturelle des oiseaux de l'Amerique septentrionale" (1807–1808?). Vieillot pioneered in the use of life histories and habits in classification. Alexander Wilson composed a nine-volume work, "American Ornithology", published 1808-1814, which is the first such record of North American birds, significantly antedating Audubon. In the early 19th century, Lewis and Clark studied and identified many birds in the western United States. John James Audubon, born in 1785, observed and painted birds in France and later in the Ohio and Mississippi valleys. From 1827 to 1838, Audubon published "The Birds of America", which was engraved by Robert Havell Sr. and his son Robert Havell Jr. Containing 435 engravings, it is often regarded as the greatest ornithological work in history.
https://en.wikipedia.org/wiki?curid=42967
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Previously a relatively unknown drug to North American athletes, Furazabol gained notoriety in the Commission of Inquiry into the Use of Drugs and Banned Practices Intended to Increase Athletic Performance (known colloquially as the Dubin inquiry). After winning the 100m gold at the 1988 Summer Olympics in Seoul, Canadian sprinter Ben Johnson tested positive for the anabolic steroid Stanozolol, was later stripped of his gold medal, and banned from competition for two years. Johnson initially denied the allegations, asserting he had never taken banned substances. He later claimed the positive finding was the result of sabotage, and that he had actually taken Furazabol, which at the time could not be detected by the Gas Chromatography-Mass Spectrometry assay used to analyze samples at the Games. Contrariwise, Stanozolol had been widely used in elite athlete circles since the 1970s, and as of 1988, could be reliably identified by conventional testing procedures.
https://en.wikipedia.org/wiki?curid=6170515
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The fish tapeworm has a long documented history of infecting people who regularly consume fish and especially those whose customs include the consumption of raw or undercooked fish. In the 1970s, most of the known cases of diphyllobothriasis came from Europe (5 million cases), and Asia (4 million cases) with fewer cases coming from North America and South America, and no reliable data on cases from Africa or Australia. Despite the relatively small number of cases seen today in South America, some of the earliest archeological evidence of diphyllobothriasis comes from sites in South America. Evidence of "Diphyllobothrium spp." has been found in 4,000- to 10,000-year-old human remains on the western coast of South America. There is no clear point in time when "Diphyllobothrium latum" and related species were “discovered” in humans, but it is clear that diphyllobothriasis has been endemic in human populations for a very long time. Due to the changing dietary habits in many parts of the world, autochthonous, or locally acquired, cases of diphyllobothriasis have recently been documented in previously non-endemic areas, such as Brazil. In this way, diphyllobothriasis represents an emerging infectious disease in certain parts of the world where cultural practices involving eating raw or undercooked fish are being introduced.
https://en.wikipedia.org/wiki?curid=9533724
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