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Brush was raised on a farm about 10 miles from downtown Cleveland. He had a great interest in science, particularly with Humphry Davy's experiments with the arc light; he tinkered with and built simple electrical devices such as a static electricity machine at age 12, experimenting in a workshop on his parents' farm. Brush attended Central High School in Cleveland where he built his first arc light, and graduated there with honors in 1867. His high school commencement oration was on the "Conservation of Force". He received his college undergraduate education from the University of Michigan, where he studied mining engineering, graduating in 1869 (there were no majors—as there are today—in electrical engineering). At Michigan, Brush was a member of Delta Kappa Epsilon fraternity (Omicron chapter). Brush earned his PhD at Western Reserve (now Case Western Reserve University), graduating in 1880.
https://en.wikipedia.org/wiki?curid=2695377
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Ares I-X had been scheduled for launch on October 27, 2009, the 48th anniversary of the first Saturn I launch. The launch attempt was delayed due to weather plus other last-minute concerns. The ground crew experienced difficulty removing a protective cover from an important nose-mounted five-port sensor package. A private watercraft had blundered into the restricted downrange safety zone and had to be chased away. Launching through the day's high cirrus clouds could have caused triboelectrification, potentially interfering with range safety communication and hampering the RSO's ability to issue the self-destruction command. Launch Director Ed Mango repeatedly delayed resumption of the countdown from the planned hold point at T-00:04:00. Ultimately, constraints of the 4-hour launch window, coupled with high clouds and other last-minute concerns, caused the mission to be scrubbed for the day at 15:20 UTC on October 27, 2009. Launch was rescheduled for a four-hour window opening at 12:00 UTC on October 28, 2009.
https://en.wikipedia.org/wiki?curid=11513600
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Tephritids are small to medium-sized (2.5–10 mm) flies that are often colourful, and usually with pictured wings, the subcostal vein curving forward at a right angle. The head is hemispherical and usually short. The face is vertical or retreating and the frons is broad. Ocelli and cellar bristles are present. The postvertical bristles are parallel to divergent. Two to eight pairs of frontal bristles are seen (at least one but usually several lower pairs curving inwards and at least one of the upper pairs curving backwards). In some species, the frontal bristles are inserted on a raised tubercle. Interfrontal setulae are usually absent or represented by one or two tiny setulae near the lunula. True vibrissae are absent, but several genera have strong bristles near the vibrissal angle. The wings usually have yellow, brown, or black markings or are dark-coloured with lighter markings. In a few species, the wings are clear. The costa has both a humeral and a subcostal break. The apical part of the subcostal is usually indistinct or even transparent and at about a right angle with respect to the basal part. Crossvein BM-Cu is present; the cell cup (posterior cubital cell or anal cell) is closed and nearly always narrowing to an acute angle. It is closed by a geniculated vein (CuA2). The CuA2 vein is rarely straight or convex. The tibiae lack a dorsal preapical bristle. The female has an oviscape.
https://en.wikipedia.org/wiki?curid=2255608
1,096,036
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Parametricism emerged as a theory-driven avant-garde design movement in the early 1990s, with its earliest practitioners – Greg Lynn, Jesse Reiser, Lars Spuybroek, Kas Oosterhuis among many others – harnessing and adapting the then new digital animation software and other advanced computational processes that had been introduced within architecture much earlier by pioneers like John Frazer and Paul Coates, but that only spread to make an impact within avant-garde architecture in the last 10–15 years. Schumacher has said that he believes the work of Frei Otto (1925 - 2015) is a precursor of Parametricism, as Frei "used physical processes as simulations and design engines to 'find' form rather than to draw conventional or invented forms. The inherent lawfulness of the engaged physical processes produced a combination of complexity, rigor and elegance that was otherwise unattainable. The power and beauty of this approach was striking."
https://en.wikipedia.org/wiki?curid=46395472
1,068,858
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The D-JET is powered by a single Williams FJ33-4A turbofan engine, which is equipped with an electronically controlled full-authority digital engine control (FADEC) system. Various functions, such as engine startup and over-speed selection prevention, have been automated and are seamlessly performed by the FADEC system. For redundancy, the dual-channel FADEC system uses four independent electrical power sources in addition to battery backup. Diamond opted to adopt a centerline location for the engine, air for which is fed through inlets embedded into the wing roots. The central location of the engine places makes it close to the center of gravity of the D-JET, reducing pitch forces, however, there are some drawbacks to this approach, including elevated air losses within the ducting arrangement used and a greater likelihood of foreign object ingestion.
https://en.wikipedia.org/wiki?curid=8087203
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During dental/orthodontic imaging, the CBCT scanner rotates around the patient's head, obtaining up to nearly 600 distinct images. For interventional radiology, the patient is positioned offset to the table so that the region of interest is centered in the field of view for the cone beam. A single 200 degree rotation over the region of interest acquires a volumetric data set. The scanning software collects the data and reconstructs it, producing what is termed a "digital volume" composed of three-dimensional voxels of anatomical data that can then be manipulated and visualized with specialized software. CBCT shares many similarities with traditional (fan beam) CT however there are important differences, particularly for reconstruction. CBCT has been described as the gold standard for imaging the oral and maxillofacial area.
https://en.wikipedia.org/wiki?curid=31286836
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The comparison was even more favourable against other high-power engines under development. The cumbersome DB 606, the first-ever "high-output" powerplant developed in Germany, consisted of two DB 601's mounted to a single reduction gear case on their front ends, that delivered with a weight of , and was ft) in size. Their troubled use and deficient installation design in the He 177A, Germany's only heavy bomber aircraft to see production and front-line service, prompted "Reichsmarschall" Hermann Göring to derisively label them in the late summer of 1942 as "welded-together engines". Conversely, the RLM was excited by the possibilities of the much more compact Jumo 222's design features, and the X engine configuration, 24 cylinder DB 604, of similar weight and displacement to the 222A but with somewhat lower specific power output. The RLM based their entire Bomber B program on pairs of these engines, which would deliver a bomber with the warload of the He 177 and even better speed than the Ju 88, a truly universal design.
https://en.wikipedia.org/wiki?curid=705691
1,205,832
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Early developments in organometallic chemistry include Louis Claude Cadet's synthesis of methyl arsenic compounds related to cacodyl, William Christopher Zeise's platinum-ethylene complex, Edward Frankland's discovery of diethyl- and dimethylzinc, Ludwig Mond's discovery of Ni(CO), and Victor Grignard's organomagnesium compounds. (Though not always acknowledged as an organometallic compound, Prussian blue, a mixed-valence iron-cyanide complex, was first prepared in 1706 by paint maker Johann Jacob Diesbach as the first coordination polymer and synthetic material containing a metal-carbon bond.) The abundant and diverse products from coal and petroleum led to Ziegler–Natta, Fischer–Tropsch, hydroformylation catalysis which employ CO, H, and alkenes as feedstocks and ligands.
https://en.wikipedia.org/wiki?curid=22526
983,338
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Doubled haploids can be produced "in vivo" or "in vitro". Haploid embryos are produced "in vivo" by parthenogenesis, pseudogamy, or chromosome elimination after wide crossing. The haploid embryo is rescued, cultured, and chromosome-doubling produces doubled haploids. The "in vitro" methods include gynogenesis (ovary and flower culture) and androgenesis (anther and microspore culture). Androgenesis is the preferred method. Another method of producing the haploids is wide crossing. In barley, haploids can be produced by wide crossing with the related species "Hordeum bulbosum"; fertilization is affected, but during the early stages of seed development the "H. bulbosum" chromosomes are eliminated leaving a haploid embryo. In tobacco ("Nicotiana tabacum"), wide crossing with "Nicotiana africana" is widely used. When "N. africana" is used to pollinate "N. tabacum", 0.25 to 1.42 percent of the progeny survive and can readily be identified as either F1 hybrids or maternal haploids. Although these percentages appear small, the vast yield of tiny seeds and the early death of most seedlings provide significant numbers of viable hybrids and haploids in relatively small soil containers. This method of interspecific pollination serves as a practical way of producing seed-derived haploids of "N. tabacum", either as an alternative method or complementary method to anther culture.
https://en.wikipedia.org/wiki?curid=14436317
1,463,796
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Hoffman last flew on STS-75 (February 22 – March 9, 1996) on the Space Shuttle "Columbia". This was a 16-day mission whose principal payloads were the reflight of the Tethered Satellite System (TSS) and the third flight of the United States Microgravity Payload (USMP-3). The TSS successfully demonstrated the ability of tethers to produce electricity. The TSS experiment produced a wealth of new information on the electrodynamics of tethers and plasma physics before the tether broke at 19.7 km, just shy of the 20.7 km goal. The crew also worked around the clock performing combustion experiments and research related to USMP-3 microgravity investigations. During this mission, Hoffman became the first astronaut to log 1000 hours aboard the Space Shuttle.
https://en.wikipedia.org/wiki?curid=557493
1,188,578
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In 1934, Volwiler and Tabern synthesized the first intravenous general anesthetic, Sodium thiopental, in 1934. In the mid 1930s, Volwiler and Tabern spent three years screening over 200 candidate compounds in search of a substance which could be injected directly into the blood stream to produce unconsciousness. They eventually discovered that 5-ethyl-5-(1-methylbutyl)-2-thiobarbituric acid, a sulfur-bearing analogue of Nembutal, was fast, effective and lacked side effects such as twitching or delirium. Sodium thiopental was first used in humans on 8 March 1934 by Ralph M. Waters in an investigation of its properties, which were short-term anesthesia and surprisingly little analgesia. Three months later, John Silas Lundy started clinical trials of thiopental at the Mayo Clinic at the request of Abbott Laboratories. Volwiler and Tabern were awarded U.S. Patent No. 2,153,729 in 1939 for the discovery of thiopental.
https://en.wikipedia.org/wiki?curid=2470275
1,919,760
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Athletic competition between the Soviet Union and United States had grown intense during the 1950s. Their opposing ideologies and interests in nations such as East and West Germany, China and North and South Korea created a delicate situation as the 1960 Winter Games approached. Of particular interest was the question of whether China would be allowed to participate. Chinese athletes last competed at the 1952 Summer Games but had since withdrawn from the IOC due to a dispute over Taiwan's participation as a separate country. The US supported Taiwan while the Soviet Union stood behind China. Given that the 1960 Games were to be held in the US, there was concern among IOC members that the host nation would not allow China or any other Communist country to take part. In 1957, IOC president Avery Brundage, an American, announced that if the US refused entry to any country recognized by the IOC, they would revoke Squaw Valley's invitation to host the Games and he would resign the presidency. The US did allow athletes from Communist countries to participate. China continued calls for Taiwan to be expelled from the IOC, demands that were refused until China broke off relations ending any hope they would participate in the 1960 Games.
https://en.wikipedia.org/wiki?curid=163231
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Although there is an overwhelming scientific consensus that global surface temperatures have increased in recent decades due to human-induced emissions of greenhouse gases, neither Trump nor any of the department heads he appointed believe that global warming is human-related. Following Trump's election, large amounts of climate information from the EPA website was altered or removed. There was widespread concern among environmentalists and scientists, and a coalition of scientific and academic groups began to make copies of the EPA web pages before they were deleted. According to the Environmental Data & Governance Initiative which tracks changes to government websites under the Trump administration, over 200 web pages providing climate information were removed during Trump's first year in office. Other pages were altered, often under Pruitt's personal direction, to remove mentions of climate and climate change.
https://en.wikipedia.org/wiki?curid=65365100
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Data storage was strictly serial on paper tape, and then later to magnetic tape: the use of data storage within readily accessible memory was not cost-effective until hard disk drives were first invented and began shipping in 1957. Significant developments took place in 1959 with IBM announcing the 1401 computer and in 1962 with ICT (International Computers & Tabulators) making delivery of the ICT 1301. Like all machines during this time the processor together with the peripherals – magnetic tape drives, disks drives, drums, printers and card and paper tape input and output required considerable space in specially constructed air conditioned accommodation. Often parts of the punched card installation, in particular sorters, were retained to present the card input to the computer in a pre-sort form that reduced the processing time involved in sorting large amounts of data.
https://en.wikipedia.org/wiki?curid=462545
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A turbofan engine is much the same as a turbojet, but with an enlarged fan at the front that provides thrust in much the same way as a ducted propeller, resulting in improved fuel efficiency. Though the fan creates thrust like a propeller, the surrounding duct frees it from many of the restrictions that limit propeller performance. This operation is a more efficient way to provide thrust than simply using the jet nozzle alone, and turbofans are more efficient than propellers in the transsonic range of aircraft speeds and can operate in the supersonic realm. A turbofan typically has extra turbine stages to turn the fan. Turbofans were among the first engines to use multiple "spools"—concentric shafts that are free to rotate at their own speed—to let the engine react more quickly to changing power requirements. Turbofans are coarsely split into low-bypass and high-bypass categories. Bypass air flows through the fan, but around the jet core, not mixing with fuel and burning. The ratio of this air to the amount of air flowing through the engine core is the bypass ratio. Low-bypass engines are preferred for military applications such as fighters due to high thrust-to-weight ratio, while high-bypass engines are preferred for civil use for good fuel efficiency and low noise. High-bypass turbofans are usually most efficient when the aircraft is traveling at 500 to 550 miles per hour (800 to 885 km/h), the cruise speed of most large airliners. Low-bypass turbofans can reach supersonic speeds, though normally only when fitted with afterburners.
https://en.wikipedia.org/wiki?curid=158681
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The longer term goal, after accomplishing the primary goal of discovering gravitational waves, Virgo aims at being part of the birth of a new branch of astronomy by observing the Universe with a different and complementary perspective than current telescopes and detectors. Information brought by gravitational waves will be added to those provided by the study of the electromagnetic spectrum (microwaves, radio waves, infrared, the visible spectrum, ultraviolet, X-rays and gamma rays), of cosmic rays and of neutrinos. In order to correlate a gravitational wave detection with visible and localized events in the sky, the LIGO and Virgo collaborations have signed bilateral agreements with many teams operating telescopes to quickly inform (on the timescale of a few days or a few hours) these partners that a potential gravitational wave signal has been observed. These alerts must be sent before knowing whether the signal is real or not, because the source (if it is real) may only remain visible during a short amount of time.
https://en.wikipedia.org/wiki?curid=6762618
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Forced circulation evaporators in the food industry use modified designs that mimic the original system however involve extra secondary steam units to enhance forced circulation flow. Whilst the single effect design employs a condenser unit to stimulate a condensation action subsequent to vapour inflow from the heat exchanger, the double effect design does a similar duty however the extra component acts to reduce the overall pressure in the system. In comparison, the triple effect system is used when high levels of effective evaporation are needed with minimum labour. In this design, the liquid enters the third effect at a low temperature and moves to the second stream in which concentration is increased due to the previous evaporation effect. Finally, the optimum product concentration is achieved in the first effect.
https://en.wikipedia.org/wiki?curid=40797269
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In order to avoid excessive pressure build-up in the hydraulic power network, a release valve was fitted beside the main hall of the powerhouse. A tall water fountain, the Jet d'Eau, was ejected by the device whenever it was activated. This typically happened at the end of the day when the factories switched off their machines, making it hard to control the pressure in the system, and to adjust the supply of pressurized water to match the actual demand. The tall fountain was visible from a great distance and became a landmark in the city. When an engineering solution was found which made the fountain redundant, there was an outcry, and in 1891 it was moved to its current location in the lake, where it operated solely as a tourist attraction, although the water to create it still came from the hydraulic network.
https://en.wikipedia.org/wiki?curid=4488634
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Launched at 12:33 a.m. Eastern Standard Time (EST) on December 7, 1972, following the only launch-pad delay in the course of the whole Apollo program that was caused by a hardware problem, Apollo 17 was a "J-type" mission that included three days on the lunar surface, expanded scientific capability, and the use of the third Lunar Roving Vehicle (LRV). Cernan and Schmitt landed in the Taurus–Littrow valley, completed three moonwalks, took lunar samples and deployed scientific instruments. Orange soil was discovered at Shorty crater; it proved to be volcanic in origin, although from early in the Moon's history. Evans remained in lunar orbit in the command and service module (CSM), taking scientific measurements and photographs. The spacecraft returned to Earth on December 19.
https://en.wikipedia.org/wiki?curid=1971
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In mid-1958, Kilby, a newly employed engineer at Texas Instruments (TI), did not yet have the right to a summer vacation. He spent the summer working on the problem in circuit design that was commonly called the "tyranny of numbers", and he finally came to the conclusion that the manufacturing of circuit components "en masse" in a single piece of semiconductor material could provide a solution. On September 12, he presented his findings to company's management, which included Mark Shepherd. He showed them a piece of germanium with an oscilloscope attached, pressed a switch, and the oscilloscope showed a continuous sine wave, proving that his integrated circuit worked, and thus that he had solved the problem. U.S. Patent 3,138,743 for "Miniaturized Electronic Circuits", the first integrated circuit, was filed on February 6, 1959. Along with Robert Noyce (who independently made a similar circuit a few months later), Kilby is generally credited as co-inventor of the integrated circuit.
https://en.wikipedia.org/wiki?curid=64069
1,020,491
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In addition to considerations of the nature of medical testing noted above, other realities can lead to misconceptions and unjustified expectations among patients. These include: Different labs have different normal reference ranges; slightly different values will result from repeating a test; "normal" is defined by a spectrum along a bell curve resulting from the testing of a population, not by "rational, science-based, physiological principles"; sometimes tests are used in the hope of turning something up to give the doctor a clue as to the nature of a given condition; and imaging tests are subject to fallible human interpretation and can show "incidentalomas", most of which "are benign, will never cause symptoms, and do not require further evaluation," although clinicians are developing guidelines for deciding when to pursue diagnoses of incidentalomas.
https://en.wikipedia.org/wiki?curid=12439068
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Beginning in 2000, the Medical University of South Carolina has hosted the annual Ernest E. Just Symposium to encourage non-white students to pursue careers in biomedical sciences and health professions. In 2008, a National Science Foundation-funded symposium honoring Just and his scientific work was held on the campus of Howard University, where he was a faculty member from 1907 until his death in 1941. Many of the speakers at the symposium contributed papers to a special issue of the journal "Molecular Reproduction and Development" dedicated to Just that was published in 2009. Since 1994 the American Society for Cell Biology has given an award and hosted a lecture in Just's name. At least two of the institutions with which Just was associated have established prizes or symposia in his name: The University of Chicago, where Just received his PhD (in zoology, in 1916), and Dartmouth College, where he received his undergraduate degree. In 2013, an international symposium honoring Just was held at the Stazione Zoologica Anton Dohrn in Naples, Italy, where Just had worked starting in 1929.
https://en.wikipedia.org/wiki?curid=7575460
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The mutation alters the structure and function of skeletal muscles producing one of three forms of myopathy: type 3 nemaline myopathy, congenital myopathy with an excess of thin myofilaments (CM) and congenital myopathy with fibre type disproportion (CMFTD). Mutations have also been found that produce core myopathies. Although their phenotypes are similar, in addition to typical nemaline myopathy some specialists distinguish another type of myopathy called actinic nemaline myopathy. In the former, clumps of actin form instead of the typical rods. It is important to state that a patient can show more than one of these phenotypes in a biopsy. The most common symptoms consist of a typical facial morphology (myopathic facies), muscular weakness, a delay in motor development and respiratory difficulties. The course of the illness, its gravity, and the age at which it appears are all variable and overlapping forms of myopathy are also found. A symptom of nemaline myopathy is that "nemaline rods" appear in differing places in type 1 muscle fibres. These rods are non-pathognomonic structures that have a similar composition to the Z disks found in the sarcomere.
https://en.wikipedia.org/wiki?curid=438944
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After Akeley's unexpected death during the Eastman-Pommeroy expedition in 1926, responsibility of the hall's completion fell to James L. Clark, who hired architectural artist James Perry Wilson in 1933 to assist Leigh in the painting of backgrounds. Wilson made many improvements on Leigh's techniques, including a range of methods to minimize the distortion caused by the dioramas' curved walls. In 1936, William Durant Campbell, a wealthy board member with a desire to see Africa, offered to fund several dioramas if allowed to obtain the specimens himself. Clark agreed to this arrangement, resulting in the acquisition of numerous large specimens. Kane joined Leigh, Wilson, and several other artists in completing the hall's remaining dioramas. Though construction of the hall was completed in 1936, the dioramas gradually opened between the mid-1920s and early 1940s.
https://en.wikipedia.org/wiki?curid=399990
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Conduction aphasia affects a subject's ability to reproduce speech (typically by repetition), though it has no influence on the subject's ability to comprehend spoken language. This shows that conduction aphasia must reflect not an impairment of the auditory ventral pathway but instead of the auditory dorsal pathway. Buchsbaum et al found that conduction aphasia can be the result of damage, particularly lesions, to the Spt (Sylvian parietal temporal). This is shown by the Spt's involvement in acquiring new vocabulary, for while experiments have shown that most conduction aphasiacs can repeat high-frequency, simple words, their ability to repeat low-frequency, complex words is impaired. The Spt is responsible for connecting the motor and auditory systems by making auditory code accessible to the motor cortex. It appears that the motor cortex recreates high-frequency, simple words (like "cup") in order to more quickly and efficiently access them, while low-frequency, complex words (like "Sylvian parietal temporal") require more active, online regulation by the Spt. This explains why conduction aphasiacs have particular difficulty with low-frequency words which requires a more hands-on process for speech production. "Functionally, conduction aphasia has been characterized as a deficit in the ability to encode phonological information for production," namely because of a disruption in the motor-auditory interface. Conduction aphasia has been more specifically related to damage of the arcuate fasciculus, which is vital for both speech and language comprehension, as the arcuate fasiculus makes up the connection between Broca and Wernicke's areas.
https://en.wikipedia.org/wiki?curid=2956315
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While there is limited surviving documentation of the martial arts of classical antiquity (such as Greek wrestling or gladiatorial combat), surviving dedicated technical treatises or martial arts manuals date to the Late Middle Ages and the early modern period. For this reason, the focus of HEMA is "de facto" on the period of the half-millennium of ca. 1300 to 1800, with a German and an Italian school flowering in the Late Middle Ages and the Renaissance (14th to 16th centuries), followed by Spanish, Portuguese, French, English, and Scottish schools of fencing in the modern period (17th and 18th centuries). Arts of the 19th century such as classical fencing, and even early hybrid styles such as Bartitsu, may also be included in the term HEMA in a wider sense, as may traditional or folkloristic styles attested in the 19th and early 20th centuries, including forms of folk wrestling and traditional stick-fighting methods.
https://en.wikipedia.org/wiki?curid=858344
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Assistive Technology Acts provide federal funding from the U.S. Department of Education to each state and territory to support "State efforts to improve the provision of assistive technology to individuals with disabilities of all ages through comprehensive statewide programs of technology-related assistance." Assistive Technologies are equipment, items or devices used to improve or keep the functionality of an individual with a disability. This will allow an individual with a disability to be more independent in life, this includes: education, recreation, and any daily activity. The services being offered for Assistive Technology include being able to use AT devices, assessment for the devices, and any maintenance included, such as customization, repair, and training. Under the Assistive Technology laws, federal grants are granted to each state to fund an Assistive Technology Act Project (ATAP) which provide services for individuals with disabilities, their families, guardians and more for their life span. The act, first passed in 1988, expires each years and needs to be continuously renewed to ensure the services can still be used.
https://en.wikipedia.org/wiki?curid=31894512
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The first electronic ignition (a cold cathode type) was tested in 1948 by Delco-Remy,<ref name="Super Street Cars, 9/81, p.34">"Super Street Cars", 9/81, p.34.</ref> while Lucas introduced a transistorized ignition in 1955, which was used on BRM and Coventry Climax Formula One engines in 1962. The aftermarket began offering EI that year, with both the AutoLite Electric Transistor 201 and Tung-Sol EI-4 (thyratron capacitive discharge) being available.<ref name="Super Street Cars, 9/81, p.35">"Super Street Cars", 9/81, p.35.</ref> Pontiac became the first automaker to offer an optional EI, the breakerless magnetic pulse-triggered Delcotronic, on some 1963 models; it was also available on some Corvettes. The first commercially available all solid-state (SCR) capacitive discharge ignition was manufactured by Hyland Electronics in Canada also in 1963. Ford fitted a FORD designed breakerless system on the Lotus 25s entered at Indianapolis the next year, ran a fleet test in 1964, and began offering optional EI on some models in 1965. This electronic system was utilized on the GT40s campaigned by Shelby American and Holman and Moody. Robert C. Hogle, Ford Motor Company, presented the, "Mark II-GT Ignition and Electrical System", Publication #670068, at the SAE Congress, Detroit, Michigan, January 9–13, 1967. Beginning in 1958, Earl W. Meyer at Chrysler worked on EI, continuing until 1961 and resulting in use of EI on the company's NASCAR hemis in 1963 and 1964.
https://en.wikipedia.org/wiki?curid=362070
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In January 2012, British Defence Minister Philip Hammond visited the United States to seek clarification about the impact of the new American military strategy on the availability of the F-35 for Britain's new carriers. In May 2012, Hammond announced that the UK coalition government had reverted to the previous government's plan to operate the F-35B STOVL variant, due to rising estimated shipbuilding costs associated with the F-35C, and an earlier estimated in-service date for the F-35B. In July 2012, Hammond stated that an initial 48 F-35Bs would be purchased to equip the carrier fleet, but a final figure of F-35 purchases would not be decided until the Strategic Defence and Security Review in 2015 – it was also suggested that the UK may later purchase F-35A variants to replace the country's Eurofighter Typhoon fleet.
https://en.wikipedia.org/wiki?curid=28702755
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Throughout the late 1940s and 1950s, the French Air Staff also had considerable interest in rocket-powered aircraft. According to author Michel van Pelt, French Air Force officials were against a pure rocket-powered flight but favoured a mixed-propulsion approach, using a combination of rocket and turbojet engines. While the Société d'Etudes pour la Propulsion par Réaction (SEPR) set about developing France's own domestic rocket engines, the French aircraft manufacturer SNCASE was aware of the French Air Force's keenness for a capable point defence interceptor aircraft, and thus begun work on the SNCASE SE.212 Durandal. In comparison to other French mixed-power experimental aircraft, such as the competing SNCASO Trident prototype interceptor, it was a heavier aircraft, intended to fly primarily on its jet engine rather than its rocket motor. A pair of prototype aircraft were constructed; on 20 April 1956, the first performed its maiden flight, initially flying only using jet power. It was the second prototype that first made use of the rocket motor during April 1957. During flight testing, a maximum speed of was attained at an altitude of, even without using the extra power of the rocket motor; this rose to 1667 km/h at 11,800 m while the rocket was active. A total of 45 test flights were performed prior to work on the programme being terminated.
https://en.wikipedia.org/wiki?curid=977522
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Each dispatch determinant is made up of three pieces of information, which builds the determinant in a number-letter-number format. The first component, a number from 1 to 36, indicates a complaint or specific protocol from the MPDS: the selection of this card is based on the initial questions asked by the emergency dispatcher. The second component, a letter A through E (including the Greek character Ω), is the response determinant indicating the potential severity of injury or illness based on information provided by the caller and the recommended type of response. The third component, a number, is the sub-determinant and provides more specific information about the patient's specific condition. For instance, a suspected cardiac or respiratory arrest where the patient is not breathing is given the MPDS code 9-E-1, whereas a superficial animal bite has the code 3-A-3. The MPDS codes allow emergency medical service providers to determine the appropriate response mode (e.g. "routine" or "lights and sirens") and resources to be assigned to the event. Some protocols also utilise a single-letter suffix which may be added to the end of the code to provide additional information, e.g. the code 6-D-1 is a patient with breathing difficulties who is not alert, 6-D-1A is a patient with breathing difficulties who is not alert and also has asthma, and 6-D-1E is a patient with breathing difficulties who is not alert and has emphysema/COAD/COPD.
https://en.wikipedia.org/wiki?curid=15390174
1,115,253
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There is a need to analyze the dissolved gas content of aqueous solutions. Dissolved gases can directly interact with aquatic organisms or can volatilize from solution (the latter described by Henry's law). These processes can result in exposure that, depending on the nature of the dissolved material, can have negative health effects. There is natural occurrence of various dissolved gases in groundwater and can be a measure of health for lakes, streams, and rivers. Dissolved gases also occur as a result of human contamination from fuel and chlorinated spill sites. As such, headspace gas chromatography offers a method for determining if there is natural biodegradation processes occurring in contaminated aquifers. For example, fuel hydrocarbons will break down into methane. Chlorinated solvents such as trichloroethylene, break down into ethene and chloride. Detecting these compounds can determine if biodegradation processes are occurring and possibly at what rate. Natural gas extracted from the earth also contains many low molecular weight hydrocarbon compounds such as methane, ethane, propane, and butane. For example, methane has been found in many water wells in West Virginia.
https://en.wikipedia.org/wiki?curid=44676619
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For functional genomics, metabolomics can be an excellent tool for determining the phenotype caused by a genetic manipulation, such as gene deletion or insertion. Sometimes this can be a sufficient goal in itself—for instance, to detect any phenotypic changes in a genetically modified plant intended for human or animal consumption. More exciting is the prospect of predicting the function of unknown genes by comparison with the metabolic perturbations caused by deletion/insertion of known genes. Such advances are most likely to come from model organisms such as "Saccharomyces cerevisiae" and "Arabidopsis thaliana". The Cravatt laboratory at The Scripps Research Institute has recently applied this technology to mammalian systems, identifying the "N"-acyltaurines as previously uncharacterized endogenous substrates for the enzyme fatty acid amide hydrolase (FAAH) and the monoalkylglycerol ethers (MAGEs) as endogenous substrates for the uncharacterized hydrolase KIAA1363.
https://en.wikipedia.org/wiki?curid=1029211
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The system was purchased by the Telecommunication Infrastructure Co., part of the Iranian government's telecom monopoly. According to the "Journal", NSN "provided equipment to Iran last year under the internationally recognized concept of 'lawful intercept,' said Mr. Roome. That relates to intercepting data for the purposes of combating terrorism, child pornography, drug trafficking, and other criminal activities carried out online, a capability that most if not all telecom companies have, he said... The monitoring center that Nokia Siemens Networks sold to Iran was described in a company brochure as allowing 'the monitoring and interception of all types of voice and data communication on all networks.' The joint venture exited the business that included the monitoring equipment, what it called 'intelligence solution,' at the end of March, by selling it to Perusa Partners Fund 1 LP, a Munich-based investment firm, Mr. Roome said. He said the company determined it was no longer part of its core business.
https://en.wikipedia.org/wiki?curid=454995
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The purpose of radio resource management is to satisfy the data rates that are requested by the users of a cellular network. The main resources are time intervals, frequency blocks, and transmit powers. Each user has its own objective function that, for example, can represent some combination of the data rate, latency, and energy efficiency. These objectives are conflicting since the frequency resources are very scarce, thus there is a need for tight spatial frequency reuse which causes immense inter-user interference if not properly controlled. Multi-user MIMO techniques are nowadays used to reduce the interference by adaptive precoding. The network operator would like to both bring great coverage and high data rates, thus the operator would like to find a Pareto optimal solution that balance the total network data throughput and the user fairness in an appropriate subjective manner.
https://en.wikipedia.org/wiki?curid=10251864
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Several years ago the government built sluice gates for the silt fertilization method, though many people disagreed with the plan. In spite of all opposition it was carried through, yet it had little success. When the torrents on Fan Shan were abundant, the gates were kept closed, and this caused damage (by flooding) of fields, tombs, and houses. When the torrents subsided in the late autumn the sluices were opened, and thus the fields were irrigated with silt-bearing water, but the deposit was not as thick as what the peasants call 'steamed cake silt' (so they were not satisfied). Finally the government got tired of it and stopped. In this connection I remember reading the "Jiayipan" of Bai Juyi (the poet) in which he says that he once had a position as Traffic Commissioner. As the Bian River was getting so shallow that it hindered the passage of boats he suggested that the sluice gates along the river and canal should be closed, but the Military Governor pointed out that the river was bordered on both sides by fields which supplied army grain, and if these were denied irrigation (water and silt) because of the closing of the sluice gates, it would lead to shortages in army grain supplies. From this I learnt that in the Tang period there were government fields and sluice gates on both sides of the river, and that irrigation was carried on (continuously) even when the water was high. If this could be done (successfully) in old times, why can it not be done now? I should like to enquire further about the matter from experts.
https://en.wikipedia.org/wiki?curid=10444102
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The notion that transport costs and trade barriers hinder the expansion of the market is age-old. Nurkse emphasised that tariff duties, exchange controls, import quotas and other non-tariff barriers to trade are major obstacles to promoting international cooperation in exporting and importing. More specifically, due to high transport costs between nations, producers do not have an incentive to export their commodities. As a result, the amount of capital accumulation remains small. To address this problem, the United Nations produced a report in 1951 with solutions for underdeveloped countries. They suggested that they can expand their markets by forming customs unions with neighbouring countries. Also, they can adopt the system of preferential taxation or even abolish customs duties altogether. The logic was that once customs duties are removed, transport costs will fall. Consequently, prices will fall and thus the demand will rise. However, Nurkse, as an export pessimist, did not agree with this view. Export pessimism is a trade theory which is governed by the idea of "inward looking growth" as opposed to "outward looking growth". (See Import substitution industrialization)
https://en.wikipedia.org/wiki?curid=32817141
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The VeSpR telescope is a special-purpose Cassegrain design to accomplish observations that other missions are not able to perform. The use of a pre-dispersing prism to prevent long wavelengths from entering the spectrograph permits a long-aperture approach to echelle spectroscopy, and the chosen combination of imaging and dispersion scales provides high spectral resolution of emission line profiles with a several arc sec wide aperture for good sensitivity. For comparable spectral resolution the HST/STIS uses a 0.2 arc sec aperture, which provides 375 times less solid angle on the sky than a 3 x 5 arc sec region observed by this rocket telescope. For comparison, the ratio of telescope areas HST/rocket is roughly 50 times. With equivalent efficiencies, Hubble Space Telescope would need 4 hours of observing time to achieve the same S/N that the rocket obtains in 5 minutes. However, Hubble telescope is not allowed to point too close to the Sun to avoid damaging its instruments, so it cannot be used for this.
https://en.wikipedia.org/wiki?curid=41202851
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He began his academic career by joining the University of Virginia, where he was made associate professor, Depts. of Internal Medicine and Pharmacology, School of Medicine in 1970, before becoming a full professor in 1975. From 1971–81 he was Director, Clinical Research Center, UVA School of Medicine and Director, Division of Clinical Pharmacology, Dept. of Internal Medicine, UVA School of Medicine (1973–81). Murad moved to Stanford University in 1981 where he was Chief of Medicine at the Palo Alto VA Medical Center (1981–86), Associate Chairman, Dept. of Medicine, Stanford University (1984–86), and Acting Chairman, Dept. of Medicine and Acting Division Chief, Division of Respiratory Medicine from 1986–88. In 1988 he was the American Heart Association, Ciba Award Recipient. Murad left his tenure at Stanford in 1988 for a position at Abbott Laboratories, where he served as a Vice President of Pharmaceutical Discovery until founding his own biotechnology company, the Molecular Geriatrics Corporation, in 1993. Murad went back to academics and joined the University of Texas Medical School at Houston to create a new department of integrative biology, pharmacology, and physiology in 1997. There, he was the chairman of Integrative Biology and Pharmacology, professor and director emeritus of The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Disease, John S. Dunn Distinguished Chair in Physiology and Medicine, deputy director of The Brown Foundation Institute of Molecular Medicine, and later a professor at the Brown Foundation Institute of Molecular Medicine. In April 2011, he moved to the George Washington University as a professor in the Department of Biochemistry and Molecular Biology.
https://en.wikipedia.org/wiki?curid=275259
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, the U.S. shale gas boom has lowered electricity generation costs placing severe pressure on the economics of operating older existing nuclear power plants. Analysis by Bloomberg shows that over half of U.S. nuclear plants are running at a loss. The Nuclear Energy Institute has estimated that 15 to 20 reactors are at risk of early closure for economic reasons. Nuclear operators in Illinois and New York have obtained financial support from regulators, and operators in Connecticut, New Jersey, Ohio and Pennsylvania are seeking similar support. Some non-nuclear power generating companies have filed unfair competition lawsuits against these subsidies, and have raised the issue with the Federal Energy Regulatory Commission.
https://en.wikipedia.org/wiki?curid=4131402
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Built-in self-test (BIST) and Design For Test (DFT) techniques add circuitry (logic) to the chip intended to help verify that the chip, as built, implements its functional specification. The extra logic monitors input stimulus and internal signals or memory states, generally by computing checksums or by exposing internal registers via a customized scanning technique. Where DFT usually coordinates with some external testing mechanism, BIST-enabled chips incorporate custom test-pattern generators. BIST functionality often exists to perform at-speed (high speed) verification where it is not possible to use scan chains or other low-speed DFT capabilities. Both methods were originally developed to detect manufacturing errors, but also have the double-edged potential to detect some effects of malicious logic on the chip, or to be exploited by malicious logic to covertly inspect remote state within the chip.
https://en.wikipedia.org/wiki?curid=23692548
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In 1948, the study was commissioned by Congress, with a choice made between Framingham, Massachusetts and Paintsville, Kentucky. Framingham was chosen when residents showed more general interest in heart research than Paintsville. Thomas Royle Dawber was director of the study from 1949 to 1966. He was appointed as chief epidemiologist shortly after the start of the project, when it was not progressing well. The study had been intended to last 20 years; however, interest grew in part due to Dr. Dawber's efforts to promote the study and engage in fundraising after he had been transferred to Boston to accept a chairmanship of preventive medicine. By 1968, it was debated whether the original study had served its purpose and should be terminated as scheduled. A committee gathered and considered that, after 20 years of research, the Framingham study should come to an end, since their hypothesis had been tested and extensive information concerning heart diseases had been gathered. Despite this conclusion, Congress failed to accept the recommendation, instead voting to continue the study. The study has been split into different segments, or "cohorts".
https://en.wikipedia.org/wiki?curid=1471689
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Late in life, Parsons began to work out a new level of the AGIL model, which he called "A Paradigm of the Human Condition". The new level of the AGIL model crystallized in the summer of 1974. He worked out the ideas of the new paradigm with a variety of people but especially Lidz, Fox and Harold Bershady. The new metaparadigm featured the environment of the general action system, which included the physical system, the biological system, and what Parsons called the telic system. The telic system represents the sphere of ultimate values in a sheer metaphysical sense. Parsons also worked toward a more comprehensive understanding of the code-structure of social systems and on the logic of the cybernetic pattern of control facilitating the AGIL model. He wrote a bulk of notes: two being "Thoughts on the Linking of Systems" and "Money and Time". He had also extensive discussions with Larry Brownstein and Adrian Hayes on the possibility of a mathematical formalization of Parsons' theory.
https://en.wikipedia.org/wiki?curid=54041
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Education in Bolivia, as in many other areas of Bolivian life, has a divide between Bolivia's rural and urban areas. Rural illiteracy levels remain high, even as the rest of the country becomes increasingly literate. This disparity stems partly from the fact that many children living in rural area ation[dubious – discuss] are not necessarily attributable to lack of funding. Bolivia devotes 23% of its annual budget to educational expenditures, a higher percentage than in most other South American countries, albeit from a smaller national budget. A comprehensive, education reform has made some significant changes. Initiated in 1994, the reform decentralized educational funding in order to meet diverse local needs, improved teacher training and curricula, formalized and expanded intercultural bilingual education and changed the school grade system. Resistance from teachers’ unions, however, has slowed implementation of some of the intended reforms (Contreras and Talavera, 2003).
https://en.wikipedia.org/wiki?curid=2463359
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The IMU's members are Member Countries and each Member country is represented through an Adhering Organization, which may be its principal academy, a mathematical society, its research council or some other institution or association of institutions, or an appropriate agency of its government. A country starting to develop its mathematical culture and interested in building links with mathematicians all over the world is invited to join IMU as an Associate Member. For the purpose of facilitating jointly sponsored activities and jointly pursuing the objectives of the IMU, multinational mathematical societies and professional societies can join IMU as an Affiliate Member. Every four years the IMU membership gathers in a General Assembly (GA) which consists of delegates appointed by the Adhering Organizations, together with the members of the executive committee. All important decisions are made at the GA, including the election of the officers, establishment of commissions, the approval of the budget, and any changes to the statutes and by-laws.
https://en.wikipedia.org/wiki?curid=14868
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After Darwin came a mode of archaeology known as cultural, or culture history, according to which sites are grouped into distinct "cultures" to determine the geographic spread and time span of these cultures and to reconstruct the interactions and flow of ideas between them. Cultural history, as the name suggests, was closely allied with the science of history. Cultural historians employed the "normative model of culture", the principle that each culture is a set of norms governing human behaviour. Thus, cultures can be distinguished by patterns of craftsmanship; for instance, if one excavated sherd of pottery is decorated with a triangular pattern, and another sherd with a chequered pattern, they likely belong to different cultures. Such an approach naturally leads to a view of the past as a collection of different populations, classified by their differences and by their influences on each other. Changes in behaviour could be explained by diffusion whereby new ideas moved, through social and economic ties, from one culture to another.
https://en.wikipedia.org/wiki?curid=1728479
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In June 2022 the observation of a continuous time crystal was reported by a team at the Institute of Laser Physics at the University of Hamburg, supervised by Hans Keßler and Andreas Hemmerich. In periodically driven systems, time translation symmetry is broken into a discrete time-translation symmetry due to the drive. Discrete time crystals break this discrete time-translation symmetry by oscillating at a multiple of the drive frequency. In the new experiment, the drive (pump laser) was operated continuously, thus respecting the continuous time translation symmetry. Instead of a subharmonic response, the system showed an oscillation with an intrinsic frequency and a time phase taking random values between 0 and 2π, as expected for spontaneous breaking of continuous time translation symmetry. Moreover, the observed limit cycle oscillations were shown to be robust against perturbations of technical or fundamental character, such as quantum noise and, due to the openness of the system, fluctuations associated with dissipation. The system consisted of a Bose–Einstein condensate in an optical cavity, which was pumped with an optical standing wave oriented perpendicularly with regard to the cavity axis and was in a superradiant phase localizing at two bistable ground states between which it oscillated.
https://en.wikipedia.org/wiki?curid=36435766
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The Penn Museum holds approximately 1,300 skulls collected by 19th century physician Samuel George Morton. The museum acquired the collection from the Academy of Natural Sciences in 1966. Morton has long been criticized for promoting white supremacist views, leveraging science to uphold racism, poor research quality, and unethically collecting human remains without consent. Despite this, the museum claims the collection is an important historic and research resource. The museum has actively conducted research using the collection in recent years. More than a dozen crania, along with mid-19th century measuring devices, were on public display at the museum from 2012 to 2013 in an exhibit named "Year of Proof: Making and Unmaking Race". In 2018, students in the Penn and Slavery project discovered the collection includes 55 crania of enslaved people, with 53 of these crania from Havana and 2 from the United States. In July, 2020 the museum announced it would move the collection from a private classroom into storage after criticism from students and the local community. The museum is also planning to repatriate or rebury skulls of enslaved individuals.
https://en.wikipedia.org/wiki?curid=417136
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This timeline of ornithomimosaur research is a chronological listing of events in the history of paleontology focused on the ornithomimosaurs, a group of bird-like theropods popularly known as the ostrich dinosaurs. Although fragmentary, probable, ornithomimosaur fossils had been described as far back as the , the first ornithomimosaur to be recognized as belonging to a new family distinct from other theropods was "Ornithomimus velox", described by Othniel Charles Marsh in 1890. Thus the ornithomimid ornithomimosaurs were one of the first major Mesozoic theropod groups to be recognized in the fossil record. The description of a second ornithomimosaur genus did not happen until nearly 30 years later, when Henry Fairfield Osborn described "Struthiomimus" in 1917. Later in the , significant ornithomimosaur discoveries began occurring in Asia. The first was a bonebed of ""Ornithomimus"" (now "Archaeornithomimus") "asiaticus" found at Iren Debasu. More Asian discoveries took place even later in the 20th century, including the disembodied arms of "Deinocheirus mirificus" and the new genus "Gallimimus bullatus". The formal naming of the Ornithomimosauria itself was performed by Rinchen Barsbold in 1976.
https://en.wikipedia.org/wiki?curid=46674214
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Vancouver Island University offers exchange programs that allow students to study for one or two semesters overseas while remaining registered at Vancouver Island University. Current partner institutions are located in Australia, England, Finland, France, Japan, Korea, the Netherlands, New Zealand, Poland, Switzerland and the USA. Vancouver Island University also offers short-term study abroad options in some program areas; destination countries include Belgium, Belize, the Cook Islands, Indonesia, Italy, USA (New York), Tanzania, Korea, France, and Spain. Additionally, Vancouver Island University supports field schools, co-ops, practicum placements and development projects, has sister-school agreements with Japan, Korea and Thailand and educational alliances with schools in Taiwan, China, Mexico, India and Turkey.
https://en.wikipedia.org/wiki?curid=876966
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Brugada syndrome is diagnosed by identifying characteristic patterns on an electrocardiogram. The pattern seen on the ECG includes ST elevation in leads V-V with a right bundle branch block (RBBB) appearance. There may be evidence of a slowing of electrical conduction within the heart, as shown by a prolonged PR interval. These patterns may be present all the time, but may appear only in response to particular drugs (see below), when the person has a fever, during exercise, or as a result of other triggers. The ECG pattern may become more obvious by performing an ECG in which some of the electrodes are placed in different positions from usual, specifically by placing leads V and V higher up the chest wall in the 1st or 2nd intercostal spaces.
https://en.wikipedia.org/wiki?curid=155623
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Facial birth defects, an effect observed in rat offspring, occurred with the children of two out of seven female DuPont employees from the Washington Works facility from 1979 to 1981. Bucky Bailey is one of the affected individuals; DuPont, however, does not accept any liability from the toxicity of PFOA. While 3M sent DuPont results from a study that showed birth defects to rats administered PFOA and DuPont moved the women out of the Teflon production unit, subsequent animal testing led DuPont to conclude there was no reproductive risk to women, and they were returned to the production unit. However, data released in March 2009 on the community around DuPont's Washington Works plant showed "a modest, imprecise indication of an elevation in risk ... above the 90th percentile ... based on 12 cases in the uppermost category", which was deemed "suggestive of a possible relationship" between PFOA exposure and birth defects.
https://en.wikipedia.org/wiki?curid=824692
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The ratha is reminiscent of Buddhist cave architecture, such as Sala-Shikhara. Archaeologist, however, are of the opinion that the stupa suggests a shikhara (temple tower) style; there are twelve such styles depicted in all the rathas experimented by sculptors during the Pallvava period. It is also mentioned that it has palace architectural style considering its barrel vaulting and long columned porch. The roof section resembles a boat. The Bhima Ratha has a pillared open veranda, a column with a Pallava seated lion, and "horseshoe-arch dormer like projections" called "kudus". These decorations are carved on the external faces of the ratha, above the cornices which also forms the dividing line between the ground floor and the first floor of the structure. Oblong-shaped shrines are carved at the cornices linked with a passage. The small shrines have a wagon-type roof supported on lion mounted pillars. The ends of the gables have fine decorative motifs, with a miniature model of a square at the centre. The niches seen are carved with regular spacing and are supported on two pilasters. Nasikas are mentioned in inscriptions inside the temple.
https://en.wikipedia.org/wiki?curid=38101003
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Starting in the late 1960s, another shift in American perception was brought about by the growing awareness of overseas manufacturing facilities returning a lower cost product with higher quality. While lower labor rates played a key role in the lower costs, they could not justify the higher reliability of offshore products over those domestically produced. It was soon discovered that those shops with higher quality production realized design and manufacturing engineering were closely intertwined. "Machine Design" articles started to reflect this trend. For example, it's believed to be the first industrial trade magazine to run a comprehensive article explaining numerical control machining and how it relates to design engineering.
https://en.wikipedia.org/wiki?curid=22592282
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The "epistemic approach" to informal logic, on the other hand, focuses on the epistemic role of arguments. It is based on the idea that arguments aim to increase our knowledge. They achieve this by linking justified beliefs to beliefs that are not yet justified. Correct arguments succeed at expanding knowledge while fallacies are epistemic failures: they do not justify the belief in their conclusion. In this sense, logical normativity consists in epistemic success or rationality. For example, the fallacy of begging the question is a "fallacy" because it fails to provide independent justification for its conclusion, even though it is deductively valid. The Bayesian approach is one example of an epistemic approach. Central to Bayesianism is not just whether the agent believes something but the degree to which they believe it, the so-called "credence". Degrees of belief are understood as subjective probabilities in the believed proposition, i.e. as how certain the agent is that the proposition is true. On this view, reasoning can be interpreted as a process of changing one's credences, often in reaction to new incoming information. Correct reasoning, and the arguments it is based on, follows the laws of probability, for example, the principle of conditionalization. Bad or irrational reasoning, on the other hand, violates these laws.
https://en.wikipedia.org/wiki?curid=46426065
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The proton–proton chain occurs around times each second in the core, converting about 3.7 protons into alpha particles (helium nuclei) every second (out of a total of ~8.9 free protons in the Sun), or about . However, each proton (on average) takes around 9 billion years to fuse with one another using the PP chain. Fusing four free protons (hydrogen nuclei) into a single alpha particle (helium nucleus) releases around 0.7% of the fused mass as energy, so the Sun releases energy at the mass–energy conversion rate of 4.26 million metric tons per second (which requires 600 metric megatons of hydrogen), for 384.6 yottawatts (), or 9.192 megatons of TNT per second. The large power output of the Sun is mainly due to the huge size and density of its core (compared to Earth and objects on Earth), with only a fairly small amount of power being generated per cubic metre. Theoretical models of the Sun's interior indicate a maximum power density, or energy production, of approximately 276.5 watts per cubic metre at the center of the core, which is about the same power density inside a compost pile.
https://en.wikipedia.org/wiki?curid=26751
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Some of the main advantages of the bend test are it provides qualitative data for tensile, compressive, and shear strain. These results typically lead to a higher confidence level in the quality of the weld joint and process. In contrast, some of the disadvantages are it requires multiple test pieces. It is typically recommended to use a minimum of 6 different test samples. Another disadvantage is that it does not provide specific values for evaluating the joint design. Moreover, large amounts of effort may need to go into preparing the part for testing. This could cause an increase in cost and schedule depending on the complexity of the part. Lastly, like all destructive tests, the part and/or weld seam is destroyed and cannot be used.
https://en.wikipedia.org/wiki?curid=845000
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Often, no symptoms are presented with a minor "A. lumbricoides" infection, the inevitable consequence being the e.g. once a year passage of such clearly visible worm(s) on close inspection. In the case of bad infections symptoms commonly include bloody sputum, cough, fever, abdominal discomfort, intestinal ulcer(s), as well as a less commonly missed passing of the quite long worms. Ascariasis is the most common cause of Löffler's syndrome worldwide. Accompanying pathological symptoms include pulmonary infiltration, eosinophilia (symptoms of the overabundance of eosinophils in the blood such as asthma and allergic reactions), and a diagnostic symptom is, aside from standard microscopy of stools, radiographic opacities. One study has observed increases in fertility in infected women, in a similar vein to good diet and exercise, but with all of the pathological negatives and discomforts the disease carries with it, varying from host to host and again with diet.
https://en.wikipedia.org/wiki?curid=60209
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David P. Schmitt is a personality psychologist who founded the International Sexuality Description Project (ISDP). The ISDP is the largest-ever cross-cultural research study on sex and personality. Over 100 psychologists simultaneously administered an anonymous self-report survey to 17,837 individuals representing 56 different nations, 6 continents, 13 islands, and 30 languages. Direct assessments of people's personality traits and sexual behaviors have led to innovative tests of evolutionary psychology and social role theory. A second wave of the ISDP is currently underway and includes measures of subjective well-being, social dominance, sexual aggression, rape attitudes, HIV risk, and psychopathy.
https://en.wikipedia.org/wiki?curid=2822449
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A meteor shower is a celestial event in which a number of meteors are observed to radiate, or originate, from one point in the night sky. These meteors are caused by streams of cosmic debris called meteoroids entering Earth's atmosphere at extremely high speeds on parallel trajectories. Most meteors are smaller than a grain of sand, so almost all of them disintegrate and never hit the Earth's surface. Very intense or unusual meteor showers are known as meteor outbursts and meteor storms, which produce at least 1,000 meteors an hour, most notably from the Leonids. The Meteor Data Centre lists over 900 suspected meteor showers of which about 100 are well established. Several organizations point to viewing opportunities on the Internet. NASA maintains a daily map of active meteor showers.
https://en.wikipedia.org/wiki?curid=157819
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Alumino-silicate based, synthetic geopolymers provide many of the same binding properties as Portland cement. Compared to other polymer additives, many geopolymers are quite durable, with high mechanical strength and thermal stability. They react readily with calcium hydroxide in water, which allows them to act as cementitious binders. Geopolymers offer the advantage of being more environmentally friendly and energy-efficient to produce than traditional chemical additives, and can be synthesized from waste products such as mine tailings or fly ash. When these waste products are treated with an alkaline reagent, the aluminosilicate rapidly depolymerizes and polycondenses into a rigid three dimensional polymeric structure that coats and strengthens soil pores. Geopolymers have been applied to stabilize gypseous soils because of their resistance to sulfur and other chemical attacks, which weaken traditional cement.
https://en.wikipedia.org/wiki?curid=53624653
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"NetHack" is a software derivative of "Hack", which itself was inspired by "Rogue". "Hack" was created by students Jay Fenlason, Kenny Woodland, Mike Thome, and Jonathan Payne at Lincoln-Sudbury Regional High School as part of a computer class, after seeing and playing "Rogue" at the University of California Berkeley computer labs. The group had tried to get the source code of "Rogue" from Glenn Wichman and Michael Toy to build upon, but Wichman and Toy had refused, forcing the students to build the dungeon-creation routines on their own. As such, the game was named "Hack" in part for the hack-and-slash gameplay and that the code to generate the dungeons was considered a programming hack. After their classes ended, the students' work on the program also ended, though they had a working game. Fenlason provided the source code to a local USENIX conference, and eventually it was uploaded to USENET newsgroups. The code drew the attention of many players who started working to modify and improve the game as well as port it to other computer systems. "Hack" did not have any formal maintainer and while one person was generally recognized to hold the main code to the current version of "Hack", many software forks emerged from the unorganized development of the game.
https://en.wikipedia.org/wiki?curid=21489
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There is no evidence that any of the direct work of Nasir al-Din al-Tusi ever made it to Copernicus, however there is evidence that the mathematics and theories did make the journey to Europe. There were Jewish scientists and pilgrims who would make the journey from the Middle East to Europe, bringing with them Middle Eastern scientific ideas to share with their Christian counterparts. While acknowledging that this is not direct evidence that Copernicus has access to al-Tusi's work, it does show that it was possible. There was just such a Jewish scholar by the name of Abner of Burgos who wrote a book containing an incomplete version of the Tusi couple that he had learned second hand, which could have been found by Copernicus. It is important to note that his version had no proofs of the geometry either, so if Copernicus had obtained this book he would have had to complete both the proof and mechanism. Additionally, some scholars believe that, if not Jewish thinkers, it could have been transmission from the Islamic school in Maragheh, home to Nasir al-Din al-Tusi's observatory to Muslim Spain. From Spain, al-Tusi and other Islamic cosmological theories could spread through Europe. Spread of Islamic astronomy from Maragheh Observatory into Europe could have also been possible in the form of Greek translations from Gregory Choniades. There is evidence as to the means of Copernicus acquiring the Tusi couple and suspicious similarities, not only in math but in visual details as well.
https://en.wikipedia.org/wiki?curid=33642424
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Two large-scale studies have demonstrated the benefits of idebenone. The Rescue of Hereditary Optic Disease Outpatient Study (RHODOS) evaluated the effects of idebenone in 85 patients with LHON who had lost vision within the prior five years. In this study, the group taking idebenone 900 mg per day for 24 weeks showed a slight improvement in visual acuity compared to the placebo group, though the difference was not statistically significant. But patients taking idebenone were protected from further vision loss, whereas the placebo group had a steady decline in visual acuity. Further, people taking idebenone demonstrated preservation of color vision and persistence of the effects of idebenone 30 months after discontinuing therapy. A retrospective analysis of 103 LHON patients by Carelli et al. builds upon these results. This study highlighted that 44 subjects who were treated with idebenone within one year of onset of vision loss had better outcomes, and that these improvements persisted for years.
https://en.wikipedia.org/wiki?curid=1892610
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Vitamin B deficiency can lead to anemia, neurological and digestive disorders. A mild deficiency may not cause any discernible symptoms, but at levels moderately lower than normal, a range of symptoms such as feeling tired, weak, lightheadedness, headaches, dizziness, rapid breathing, rapid heartbeat, cold hands and feet, low-grade fevers, tremor, cold intolerance, easy bruising and bleeding, pale skin, low blood pressure, sore tongue, upset stomach, loss of appetite, weight loss, constipation, diarrhea, severe joint pain, feeling abnormal sensations including numbness or tingling (pins and needles) to the fingers and toes, and tinnitus, may be experienced. A wide range of associated symptoms may include angular cheilitis, mouth ulcers, bleeding gums, hair loss and thinning, premature greying, a look of exhaustion and dark circles around the eyes, as well as brittle nails.
https://en.wikipedia.org/wiki?curid=12742560
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"Wolfenstein" uses an improved version of id Software's id Tech 4 game engine, the technology behind "Doom 3" and "". The game was developed by Raven Software for Windows, PlayStation 3 and Xbox 360. The modifications to the game engine include depth of field effects, soft shadowing, post-processing effects, Havok physics, as well as the addition of a supernatural realm, called the Veil. While in the Veil the player has access to certain special abilities, such as the power to slow down time, to get around obstacles that exist on Earth, or even to be able to defeat enemies that have an otherwise impenetrable shield (similar to "Spirit Walk" from the previous id Tech 4 title "Prey"). The actress Carrie Coon started her career by doing motion caption work for "Wolfenstein". The multiplayer part was developed by Endrant Studios. "Wolfenstein" is the first in a string of id Software games not planned to have a Linux port (continued on throughout "Rage" onwards), with the person in charge of Linux ports at id, Timothee Besset, commenting that "It is unlikely the new "Wolfenstein" title is going to get a native Linux release. None of it was done in house, and I had no involvement in the project."
https://en.wikipedia.org/wiki?curid=18459313
255,882
1,864,283
In the face of continuing concerns about the economic losses that might be suffered by organic farmers by unintended intermixing, the U.S. Secretary of Agriculture convened an Advisory Committee on Biotechnology and 21st Century Agriculture (AC21) to study the issue and make recommendations as to whether to address these concerns and if so, how. economic losses to farmers caused by unintended presence of genetically engineered materials, as well as how such mechanisms might work. The members of AC21 included representatives of the biotechnology industry, the organic food industry, farming communities, the seed industry, food manufacturers, State government, consumer and community development groups, the medical profession, and academic researchers. The AC21 recommended that a study should be conducted to answer the question of whether and to what extent there are any economic losses to US organic farmers; recommended that if the losses are serious, that a crop insurance program for organic farmers be put in place, and that an education program should be undertaken to ensure that organic farmers are putting appropriate contracts in place for their crops and that neighboring GM crop farmers are taking appropriate containment measures. Overall the report supported a diverse agriculture system in which many different farming systems could co-exist.
https://en.wikipedia.org/wiki?curid=8160680
1,863,211
2,016,182
Metals commonly used in springs (e.g. high strength steel, aluminum and beryllium copper alloys) have been utilized in deformable aerospace structures for several decades with considerable success. They continue to be used in the majority of high strain deployable structure applications and excel where the greatest compaction ratios and electrical conductivity are required. But metals suffer from having high densities, high coefficients of thermal expansion, and lower strain capacities when compared to composite materials. In recent decades, the increasing need for high performance deployable structures, coupled with the emergence of a robust composite materials industry, has increased the demand and utility for High Strain Composites Structures. Today HSCs are used in a variety of niche aerospace applications, mostly in areas where extreme precision and low mass are required.
https://en.wikipedia.org/wiki?curid=42470137
2,015,020
773,020
Founded as the Environmental Systems Research Institute in 1969 as a land-use consulting firm, Esri currently has 49 offices worldwide including 11 research and development centers in the United States, Europe, the Middle East and Africa and Asia Pacific. There are 10 regional U.S. offices and over 3,000 partners globally, with users in every country and a total of over a million active users in 350,000 organizations. These include Fortune 500 companies, most national governments, 20,000 cities, all 50 US States and 7,000+ universities. The firm has 4,000 total employees, and is privately held by its founders. In a 2016 Investor's Business Daily article, Esri's annual revenues were indicated to be $1.1 billion.
https://en.wikipedia.org/wiki?curid=141435
772,604
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While at the Smithsonian Astrophysical Observatory (SAO), Abbot would work under Samuel P. Langley. Langley would go on to change his focus from solar radiation to aeronautics, with Abbot taking over solar radiation research. Abbot would participate in many expeditions. In 1900 he, along with Langley, would travel to Wadesboro, North Carolina to observe a solar eclipse, followed by another eclipse expedition to Sumatra in 1901. During his expedition experiences he would also travel to Algeria, Egypt, South Africa, Australia, and other countries, often in partnership with the National Geographic Society. Abbot would become acting director of SAO in 1906 and in 1907, Abbot became the Director of the Smithsonian Astrophysical Observatory, following the death of Samuel P. Langley. While Langley was still Director, he had visited Mount Whitney, and decided it would be a great place for an observatory. Abbot secured funding for the observatory and it was built in 1909. As Director, a position he would hold until his retirement, Abbot would open the Radiation Biology Laboratory in 1929, to study radiation effects on plants, and other organisms. This helped to develop the first wave of biophysics researchers in the United States.
https://en.wikipedia.org/wiki?curid=337070
1,795,506
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Commodification of other ecological relations as in carbon credit and direct payments to farmers to preserve ecosystem services are likewise examples that enable private parties to play more direct roles protecting biodiversity, but is also controversial in ecological economics. The United Nations Food and Agriculture Organization achieved near-universal agreement in 2008 that such payments directly valuing ecosystem preservation and encouraging permaculture were the only practical way out of a food crisis. The holdouts were all English-speaking countries that export GMOs and promote "free trade" agreements that facilitate their own control of the world transport network: The US, UK, Canada and Australia.
https://en.wikipedia.org/wiki?curid=177694
899,981
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At 07:15 UTC on 14 November 1963, the cook of "Ísleifur II", a trawler sailing these same waters, spotted a rising column of dark smoke southwest of the boat. The captain thought it might have been a boat on fire, and ordered his crew to investigate. Instead, they encountered explosive eruptions giving off black columns of ash, indicating that a volcanic eruption had begun to breach the surface of the sea. By 11:00 the same day, the eruption column had reached several kilometres in height. At first the eruptions took place at three separate vents along a northeast by southwest trending fissure, but by the afternoon the separate eruption columns had merged into one along the erupting fissure. Over the next week, explosions were continuous, and after just a few days the new island, formed mainly of scoria, measured over in length and had reached a height of .
https://en.wikipedia.org/wiki?curid=28876
991,461
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The data recorded by the FDR are used for accident and incident investigation. Due to their importance in investigating accidents, these ICAO-regulated devices are carefully engineered and constructed to withstand the force of a high speed impact and the heat of an intense fire. Contrary to the popular term "black box", the exterior of the FDR is coated with heat-resistant bright orange paint for high visibility in wreckage, and the unit is usually mounted in the aircraft's tail section, where it is more likely to survive a crash. Following an accident, the recovery of the FDR is usually a high priority for the investigating body, as analysis of the recorded parameters can often detect and identify causes or contributing factors.
https://en.wikipedia.org/wiki?curid=938385
409,343
1,860,149
Prosopagnosia is a "selective impairment in the ability to recognize individual faces due to brain damage of the visual cortex." Essentially, this neurological deficit impairs an individuals ability to recognize faces, even faces of those who should be familiar, such as family members. This is the result of damage to the visual cortex. In terms of the holistic view, the inability to recognize faces stems from a failure to integrate the individual face parts into a whole. A study done by Busigny, Joubert, Felician, Ceccaldi, & Rossion (2010) looked at a prosopagnosia patient, GG, in reference to unimpaired control participants in matching/recognition tasks. Participants were either asked to study a whole face and select a part from the studied face presented in isolation, or study an isolated part and then select the same part when presented in a whole face. The researchers hypothesized that holistic interference would be demonstrated in the "part-to-whole" and "whole-to-part" conditions relative to the "part-to-part" and "whole-to-whole" conditions. These results were confirmed in the control participants, however, patient GG performed equally well in both conditions. The researchers suggest this is due to her recognition of face parts is unaffected by surrounding facial features in encoding or retrieving it from memory. Similar studies have also been conducted to show that prosopagnosia results from an individual's inability to form a holistic facial representation.
https://en.wikipedia.org/wiki?curid=49307010
1,859,081
1,568,926
The fluence of charged particles hitting the brain of an astronaut has been estimated several times in the past. One estimate is that during a 3-year mission to Mars at solar minimum (assuming the 1972 spectrum of GCR), 20 million out of 43 million hippocampus cells and 230 thousand out of 1.3 million thalamus cell nuclei will be directly hit by one or more particles with charge Z> 15. These numbers do not include the additional cell hits by energetic electrons (delta rays) that are produced along the track of HZE nuclei or correlated cellular damage. The contributions of delta rays from GCR and correlated cellular damage increase the number of damaged cells two- to three-fold from estimates of the primary track alone and present the possibility of heterogeneously damaged regions, respectively. The importance of such additional damage is poorly understood.
https://en.wikipedia.org/wiki?curid=39761773
1,568,039
611,807
Flight day 13 saw the members of the STS-134 crew complete several major tasks. Mission specialists Mike Fincke and Greg Chamitoff replaced an absorbent bed in the Carbon Dioxide Removal Assembly (CDRA). The beds have to be changed from time to time in order for the CDRA to remove CO. While the CDRA work was on-going, commander Mark Kelly and mission specialist Drew Feustel re-sized two of the spacesuits that will be used by Expedition 28 flight engineers Ron Garan and Mike Fossum. The rest of the STS-134 crew completed more transfers between Space Shuttle "Endeavour" and the International Space Station (ISS). Commander Mark Kelly, joined by pilot Greg Johnson and Ron Garan, spoke with students, teachers and others gathered at University of Arizona in Tucson, Arizona. Johnson also spoke with representatives of Gannet, KPRC-TV and the Voice of America.
https://en.wikipedia.org/wiki?curid=18089765
611,496
2,177,946
The methodology of the RMM was firstly proposed by Young and his collaborators in 2005. The key idea is to introduce a subtracting and adding-back regularizing technique to remove the singularity of the double layer kernel function at the origin, so that the source points can be placed directly on the real boundary. Up to now, the RMM has successfully been applied to a variety of physical problems, such as potential, exterior acoustics antiplane piezo-electricity, acoustic eigenproblem with multiply-connected domain, inverse problem, possion’ equation and water wave problems. Furthermore, some improved formulations have been made aiming to further improve the feasibility and efficiency of this method, see, for example, the weighted RMM for irregular domain problems and analytical RMM for 2D Laplace problems.
https://en.wikipedia.org/wiki?curid=35549075
2,176,701
1,485,109
Different phyllosilicates are associated with different anatomical regions. This seems to be a result of when they formed. Phyllosilicates primarily form by filling voids. Voids formed in the fossils as the carbon films were heated and released volatile components. Different types of kerogen—reflecting different initial conditions—mature (i.e. volatilize) at different temperatures and pressures. The first kerogens to mature are those that replace labile tissue such as guts and organs; cuticular regions produce more robust kerogens that mature later. Kaolinite (rich in Al/Si, low in Mg) is the first phyllosilicate to form, once the rock is metamorphosed to the oil window, and thus replicates the most labile regions of the fossil. Once the rock is heated and compressed further, to the gas window, illite (rich in K/Al) and chlorite (rich in Fe/Mg) start to form; once all the available K is used up, no further illite forms, so the last tissues to mature are replicated exclusively in chlorite. The precise mineral formation depends on the porewater (and thus rock) chemistry; the thickness of the films increases as metamorphism continues; and the minerals align with the prevailing strain. They are not present in comparable deposits with very little metamorphism.
https://en.wikipedia.org/wiki?curid=17875618
1,484,272
109,031
The 2015 edition of the EPA's annual report ""Light-Duty Automotive Technology, Carbon Dioxide Emissions, and Fuel Economy Trends"" estimates the following utility factors for 2015 model year plug-in hybrids to represent the percentage of miles that will be driven using electricity by an average driver, whether in electric only or blended modes: 83% for the BMW i3 REx, 66% for the Chevrolet Volt, 45% for the Ford Energi models, 43% for the McLaren P1, 37% for the BMW i8, and 29% for the Toyota Prius PHV. A 2014 analysis conducted by the Idaho National Laboratory using a sample of 21,600 all-electric cars and plug-in hybrids, found that Volt owners traveled on average 9,112 miles in all-electric mode (e-miles) per year, while Leaf owners traveled 9,697 e-miles per year, despite the Volt's shorter all-electric range, about half of the Leaf's.
https://en.wikipedia.org/wiki?curid=1611987
108,986
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Eighty-pounder rifle: the first 80-pounder was cast at the West Point foundry with trunnions. Subsequent rifles were cast without trunnions and bronze trunnion band and trunnions were added. The gun was initially well received but soon showed a tendency to burst. , a converted Coastal Survey ship armed with one IX-inch Dahlgren and one 80-pounder Dahlgren rifle was engaged in the bombardment of Roanoke Island in support amphibious landings, when the following entry was made in her log for February 7, 1862: "At 5:15, rifled 80-pounder aft, loaded with six pounds powder and solid Dahlgren shot, 80 pounds, burst in the act of firing into four principal pieces. The gun forward of the trunnions fell on deck. One third of the breech passed over the mastheads and fell clear of the ship on the starboard bow. One struck on port quarter. And the fourth piece, weighing about 1,000 pounds, driving through the deck and magazine, bringing up on the keelson, set fire to the ship. Fire promptly extinguished."
https://en.wikipedia.org/wiki?curid=1463459
799,960
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Van Norren et al. (1998) could not find a single example in the medical literature of a <1 mW class III laser causing eyesight damage. Mainster et al. (2003) provide one case, an 11-year-old child who temporarily damaged her eyesight by holding an approximately 5 mW red laser pointer close to the eye and staring into the beam for 10 seconds; she experienced scotoma (a blind spot) but fully recovered after three months. Luttrull & Hallisey (1999) describe a similar case, a 34-year-old male who stared into the beam of a class IIIa 5 mW red laser for 30 to 60 seconds, causing temporary central scotoma and visual field loss. His eyesight fully recovered within two days, at the time of his eye exam. An intravenous fundus fluorescein angiogram, a technique used by ophthalmologists to visualise the retina of the eye in fine detail, identified subtle discoloration of the fovea.
https://en.wikipedia.org/wiki?curid=1101848
772,810
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In the women's race, Helen Jenkins powered away from the rest of the field on the run to win. With the win, Jenkins won her first World Championship series event since the format began in 2009 and booked her place on Britain's Olympic team. Despite suffering a cold, Jenkins finished ahead of first-time medalists Gwen Jorgensen and Anja Dittmer. A group of 34 formed on the bike with Diaz and Sweetland eventually bridging the gap leaving a group of 50 triathletes to go into the run section together. Jenkins surged ahead in the run to win as Jorgensen set the fastest run split to qualify for the US and claim the silver medal. Dittmer came home for bronze after out-sprinting a group containing Snowsill, Groff and Hewitt. Hewitt and Groff qualified for London whilst the Australians failed to meet their nation's criteria. Series leader Paula Findlay finished 19th as Diaz and Hewitt leapfrogged her in the overall championship, with London winner Jenkins in fourth.
https://en.wikipedia.org/wiki?curid=29804819
1,887,349
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Immediately preceding World War II, Ford developed an aircraft engine similar to the Rolls-Royce Merlin. It was a 60 degree V-12 of 1,650 cubic inch displacement with cylinder bore and stroke matching the Merlin aviation engine, using an aluminum block and head; dual overhead camshafts, and four valves per cylinder. The intention of this design was to help Ford break into the anticipated large market for aircraft engines. This engine was built to typical aircraft standards: it was light, high performance, and highly reliable. Everything was safety wired or staked with close attention to detail on every part. Available information suggests this design performed well.
https://en.wikipedia.org/wiki?curid=18866869
829,242
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Hemley's research deals with the properties of matter under high pressure with applications in geophysics, geochemistry and planetology, as well as applications in solid-state physics, chemistry, and pressure effects on biomolecules and biological systems; the applications in physics include hydrogen under pressure in the megabar range, generation of novel superconductors, magnetic structures, glasses and superhard materials under high pressure; the applications in chemistry include new compounds under high pressure. Helmley's research has been experimental ("e.g." high-pressure studies with spectroscopic methods and generating high pressures with laser-heated diamond anvil cell) and theoretical; he used theory to develop high-pressure experimental methods in conjunction with microscopic laser-optical and X-ray diffraction analysis in situ from synchrotron radiation sources. Hemley worked in the late 1980s with Ho-Kwang Mao, who became famous for his 1976 work with Peter M. Bell on extension of the laboratory pressure range up to pressures over 1 megabar. Hemley, Mao, and Bell investigated not only minerals under pressures corresponding to those in the Earth's interior but also gases and liquids under pressures believed to exist in the interiors of gas giants such as Jupiter and Saturn. In particular, they investigated the behavior of hydrogen at pressures in the megabar range.
https://en.wikipedia.org/wiki?curid=54087095
1,900,990
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UQ counts two Nobel laureates (Peter C. Doherty and John Harsanyi), over a hundred Olympians winning numerous gold medals, and 117 Rhodes Scholars among its alumni and former staff. UQ's alumni also include University of California, San Francisco Chancellor Sam Hawgood, the first female Governor-General of Australia Dame Quentin Bryce, former President of King's College London Ed Byrne, member of United Kingdom's Prime Minister Council for Science and Technology Max Lu, Oscar and Emmy awards winner Geoffrey Rush, triple Grammy Award winner Tim Munro, former CEO and Chairman of Dow Chemical Andrew N. Liveris, and current director of multiple organisations including IBM.
https://en.wikipedia.org/wiki?curid=192819
185,535
1,777,913
Implicit cognition was first discovered in the year of 1649 by Descartes in his "Passions of the Soul". He said in one of his writings that he saw that unpleasant childhood experiences remain imprinted in a child's brain until its death without any conscious memory of it remaining. Even though this idea was never accepted by any of his peers, in 1704 Gottfried Wilhelm Leibniz in his "New Essays Concerning Human Understanding" stressed the importance of unconscious perceptions which he said were the ideas that we are not consciously aware of yet still influence people's behavior. He claimed that people have residual effects of prior impressions without any remembrance of them. In 1802 French philosopher Maine de Biran in his "The Influence of Habit on the Faculty of Thinking" was the first person after Leibniz to systematically discuss implicit memory stating that after enough repetition, a habit can become automatic or completed without any conscious awareness. In 1870 Ewald Hering said that it was essential to consider unconscious memory, which is involved in the involuntary recall, and the development of automatic and unconscious habitual actions.
https://en.wikipedia.org/wiki?curid=10271359
1,776,911
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However, the principle is applied very broadly beyond bottles to paint and automobile parts such as tires. When purchasing paint or tires in many places, one simultaneously pays for the disposal of the toxic waste they become. In some countries, such as Germany, law requires attention to the comprehensive outcome of the whole extraction, production, distribution, use and waste of a product, and holds those profiting from these legally responsible for any outcome along the way. This is also the trend in the UK and EU generally. In the United States, the issue has been confronted via class action lawsuits that attempt to hold companies liable for the environmental impact of their products. Thus far, such as litigation or proposed accounting reforms such as full cost accounting have not gained much traction for the product stewardship concept in the United States beyond the realm of academe and corporate public relations (derisively referred to as greenwashing).
https://en.wikipedia.org/wiki?curid=397803
1,299,017
899,761
Goserelin is a synthetic analogue of a naturally occurring gonadotropin-releasing hormone (GnRH). Bioavailability is almost complete by injection. Goserelin is poorly protein-bound and has a serum elimination half-life of two to four hours in patients with normal renal function. The half-life increases with patients with impaired renal function. There is no significant change in pharmacokinetics in subjects with liver failure. After administration, peak serum concentrations are reached in about two hours. It rapidly binds to the GnRH receptor cells in the pituitary gland thus leading to an initial increase in production of luteinizing hormone and thus leading to an initial increase in the production of corresponding sex hormones. This initial flare may be treated by co-prescribing/co-administering an androgen receptor antagonist such as bicalutamide (Casodex). Eventually, after a period of about 14–21 days, production of LH is greatly reduced due to receptor downregulation, and sex hormones are generally reduced to castrate levels.
https://en.wikipedia.org/wiki?curid=1269468
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Sonata was commercially released in 1986, having been developed by Jonathan Ingram independently and was sold to T2 Solutions (renamed from GMW Computers in 1987 - which was eventually bought by Alias|Wavefront), and was sold as a successor to GMW's RUCAPS. It ran on workstation computer hardware (by contrast, other 2D CAD systems could run on personal computers). The system was not expensive, according to Michael Phiri. Reiach Hall purchased "three Sonata workstations on Silicon Graphics machines, at a total cost of approximately £2000 each" [1990 prices]. Approximately 1000 seats were sold between 1985 and 1992. However, as a BIM application, in addition to geometric modelling, it could model complete buildings, including complex parametrics, costs and staging of the construction process.
https://en.wikipedia.org/wiki?curid=48253668
1,856,186
1,412,946
Whether or not rule compaction has been applied, the output of an LCS algorithm is a population of classifiers which can be applied to making predictions on previously unseen instances. The prediction mechanism is not part of the supervised LCS learning cycle itself, however it would play an important role in a reinforcement learning LCS learning cycle. For now we consider how the prediction mechanism can be applied for making predictions to test data. When making predictions, the LCS learning components are deactivated so that the population does not continue to learn from incoming testing data. A test instance is passed to [P] where a match set [M] is formed as usual. At this point the match set is differently passed to a prediction array. Rules in the match set can predict different actions, therefore a voting scheme is applied. In a simple voting scheme, the action with the strongest supporting 'votes' from matching rules wins, and becomes the selected prediction. All rules do not get an equal vote. Rather the strength of the vote for a single rule is commonly proportional to its numerosity and fitness. This voting scheme and the nature of how LCS's store knowledge, suggests that LCS algorithms are implicitly "ensemble learners".
https://en.wikipedia.org/wiki?curid=854461
1,412,151
1,070,868
Since his work on fan studies, which led to his 1992 book "Textual Poachers", Jenkins' research across various topics can be understood as a continuum with an overall theme. This research theme addresses how groups and communities in online & digital media era participatory culture exercise their own agency. Such agency is exercised by tapping into and combining numerous different media sources and channels, in both officially approved and unapproved ways; when fans or users work as communities to leverage their combined expertise, a collective intelligence process is generated. One of Jenkins' key arguments is that given these cultural phenomena, media convergence is best understood by both media scholars and practitioners as a cultural process, rather than a technological end-point. The key work in Jenkins' development of this argument was his 2006 book "Convergence Culture: Where Old and New Media Collide". As described in this book, convergence culture arises from digital era post-broadcast media landscape where audiences are fragmented by the proliferation of channels and platforms while media users are more empowered than ever before to participate and collaborate – across various channels and platforms – in content creation and dissemination through their access to online networks and digital interactivity.
https://en.wikipedia.org/wiki?curid=1423953
1,070,314
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Bankers felt the real problem was that the United States was the last major country without a central bank, which might provide stability and emergency credit in times of financial crisis. While segments of the financial community were worried about the power that had accrued to JP Morgan and other 'financiers', most were more concerned about the general frailty of a vast, decentralized banking system that could not regulate itself without the extraordinary intervention of one man. Financial leaders who advocated a central bank with an elastic currency after the Panic of 1907 included Frank Vanderlip, Myron T. Herrick, William Barret Ridgely, George E. Roberts, Isaac Newton Seligman and Jacob H. Schiff. They stressed the need for an elastic money supply that could expand or contract as needed. After the scare of 1907 the bankers demanded reform; the next year, Congress established a commission of experts to come up with a nonpartisan solution.
https://en.wikipedia.org/wiki?curid=1290773
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The network's flagship owned-and-operated station, WJZ-TV in New York City, signed on the air on August 10, 1948, with its first broadcast running for two hours that evening. ABC's other owned-and-operated stations launched over the course of the next 13 months: WENR-TV in Chicago signed on the air on September 17, while WXYZ-TV in Detroit went on the air on October 9, 1948. In October 1948, as a result of an influx of television station license applications that it had issued as well as a study it undertook on the use of the VHF spectrum for broadcasting purposes, the FCC implemented a freeze on new station applications. However, KGO-TV in San Francisco, which had received its license prior to the freeze, made its debut on May 5, 1949. On May 7, 1949, "Billboard" revealed that ABC had proposed an investment of $6.25 million, of which it would spend $2.5 million to convert of land in Hollywood into what would become The Prospect Studios, and construct a transmitter on Mount Wilson, in anticipation of the launch of KECA-TV, which began operations on September 16.
https://en.wikipedia.org/wiki?curid=64765894
1,188,892
972,304
At the heart of the system, acting as pressure sink as well as suspension elements, are the so-called spheres, five or six in all; one per wheel and one main accumulator as well as a dedicated brake accumulator on some models. On later cars fitted with Hydractive or Activa suspension, there may be as many as ten spheres. Spheres consist of a hollow metal ball, open to the bottom, with a flexible Desmopan rubber membrane, fixed at the 'equator' inside, separating top and bottom. The top is filled with nitrogen at high pressure, up to 75 bar, the bottom connects to the car's hydraulic fluid circuit. The high pressure pump, powered by the engine, pressurizes the hydraulic fluid (LHM – liquide hydraulique minéral) and an accumulator sphere maintains a reserve of hydraulic power. This part of the circuit is at between 150 and 180 bars. It powers the front brakes first, prioritised via a security valve, and depending on type of vehicle, can power the steering, clutch, gear selector, etc.
https://en.wikipedia.org/wiki?curid=537169
971,794
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Proteomics deals with proteins in the same way that Genomics studies the genetic code of entire organisms, while Transcriptomics deals with the study of RNA sequencing and transcripts. While all three fields might use forms of mass spectrometry and chromatography to identify and study the functions of DNA, RNA, and proteins, proteomics relies on the assumption that current gene models are correct and that all relevant protein sequences can be found in a reference database such as the Proteomics Identifications Database. Proteogenomics helps eliminate this reliance on existing, limited genetic models by combining datasets from multiple fields in order to produce a database of proteins or genetic markers. In addition, the emergence of novel protein sequences due to mutations often cannot be accounted for in traditional proteomic databases, but can be predicted and studied using a synthesis of genomic and transcriptomic data.
https://en.wikipedia.org/wiki?curid=28722065
1,626,767
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Thomas Johann Seebeck was the first to notice an effect due to semiconductors, in 1821. In 1833, Michael Faraday reported that the resistance of specimens of silver sulfide decreases when they are heated. This is contrary to the behavior of metallic substances such as copper. In 1839, Alexandre Edmond Becquerel reported observation of a voltage between a solid and a liquid electrolyte, when struck by light, the photovoltaic effect. In 1873, Willoughby Smith observed that selenium resistors exhibit decreasing resistance when light falls on them. In 1874, Karl Ferdinand Braun observed conduction and rectification in metallic sulfides, although this effect had been discovered much earlier by Peter Munck af Rosenschold () writing for the Annalen der Physik und Chemie in 1835, and Arthur Schuster found that a copper oxide layer on wires has rectification properties that ceases, when the wires are cleaned. William Grylls Adams and Richard Evans Day observed the photovoltaic effect in selenium in 1876.
https://en.wikipedia.org/wiki?curid=27709
27,580
1,967,729
Towards the end of the decade and the beginning of the 2010s the Union made a number of improvements to their facilities to modernise them following an increase in competition and expectations of students following the increase of tuition fees in 2012. In 2008 the former Coffee Bar was renovated into 'The Cafe', the concourse entrance was completely renovated during Summer 2011, 'The Bridge' bar updated in Summer 2012 and an American Style Diner created on Bar Three in 2014. The Cube nightclub and Union Films cinema also received an update in 2016 to add a stage area at the front and to replace the seating system so it would become suitable as a lecture theatre space during the day as well. In 2014 the Students Union, in response to student concerns over exploitative lettings agencies in the city, set up a lettings agency to be an approachable and trustworthy example for students to follow requiring the union to set up a second company, SUSU Social Enterprises to enable this to happen.
https://en.wikipedia.org/wiki?curid=13484007
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The basis of the British Empire was founded in the age of mercantilism, an economic theory that stressed maximising the trade outside the empire, and trying to weaken rival empires. The 18th century British Empire was based upon the preceding English overseas possessions, which began to take shape in the late 16th and early 17th century, with the English settlement of islands of the West Indies such as Trinidad and Tobago, the Bahamas, the Leeward Islands, Barbados, Jamaica, and Bermuda, and of Virginia, one of the Thirteen Colonies which in 1776 became the United States, as well as of the Maritime provinces of what is now Canada. The sugar plantation islands of the Caribbean, where slavery became the basis of the economy, comprised England's most lucrative colonies. The American colonies also used slave labour in the farming of tobacco, indigo, and rice in the south. England, and later Great Britain's, American empire was slowly expanded by war and colonisation. Victory over the French during the Seven Years' War gave Great Britain control over what is now eastern Canada.
https://en.wikipedia.org/wiki?curid=33643110
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In rats, the median lethal dose (LD) when administered orally is 280 milligrams per kilogram (mg/kg), approximately one and a half times that of caffeine. When administered intravenously in rabbits, psilocybin's LD is approximately 12.5 mg/kg. Psilocybin comprises approximately 1% of the weight of "Psilocybe cubensis" mushrooms, and so nearly of dried mushrooms, or of fresh mushrooms, would be required for a person to reach the 280 mg/kg LD value of rats. Based on the results of animal studies, the lethal dose of psilocybin has been extrapolated to be 6 grams, 1000 times greater than the effective dose of 6 milligrams. The Registry of Toxic Effects of Chemical Substances assigns psilocybin a relatively high therapeutic index of 641 (higher values correspond to a better safety profile); for comparison, the therapeutic indices of aspirin and nicotine are 199 and 21, respectively. The lethal dose from psilocybin toxicity alone is unknown at recreational or medicinal levels, and has rarely been documented—, only two cases attributed to overdosing on hallucinogenic mushrooms (without concurrent use of other drugs) have been reported in the scientific literature and may involve other factors aside from psilocybin.
https://en.wikipedia.org/wiki?curid=38468
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The village of Rhynie in Aberdeenshire is the site of an important sedimentary deposit - Rhynie chert. The bulk of this fossil bed consists of primitive plants that had water-conducting cells and sporangia but no leaves, along with arthropods: Collembola, Opiliones (harvestmen), pseudoscorpions and the extinct, spider-like Trigonotarbids. This fossil bed is remarkable for two reasons. Firstly, the age of the find (early Devonian circa 410 Ma) makes this one of the earliest sites anywhere containing terrestrial fossils, coinciding with the first stages of the colonisation of land by plants and animals. Secondly, these cherts are famous for their exceptional state of ultrastructural preservation, with individual cell walls easily visible in polished specimens. For example, stomata have been counted and lignin remnants detected in the plant material.
https://en.wikipedia.org/wiki?curid=3338124
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