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On April 28, 2006, the Cabinet drafted a reformed version of the law which was submitted to the 164th ordinary session of the National Diet (sitting from January to June 2006). The draft is composed of a preamble and 18 articles. The new preamble does not include the phrase "the realization of the ideals laid forth in the constitution depend on the education of the people", as is stated in the current law, and includes some additions, such as the phrases "community spirit" and "the inheritance of tradition". In addition, the "purpose of education" has been divided into five items, containing such moral provisions as "to nurture an attitude[...]to love our country and our home".
https://en.wikipedia.org/wiki?curid=4001479
1,628,503
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In 1930–32, the innovative and hard-to-use "Rhythmicon" was developed by Léon Theremin at the request of Henry Cowell, who wanted an instrument which could play compositions with multiple rhythmic patterns, based on the overtone series, that were far too hard to perform on existing keyboard instruments. The invention could produce sixteen different rhythms, each associated with a particular pitch, either individually or in any combination, including en masse, if desired. Received with considerable interest when it was publicly introduced in 1932, the Rhythmicon was soon set aside by Cowell and was virtually forgotten for decades. The next generation of rhythm machines played only pre-programmed rhythms such as mambo, tango, or bossa nova.
https://en.wikipedia.org/wiki?curid=45839
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Session Data Transport (SDT) is a reliable multicast transport protocol which operates over UDP/IP which can be used to group peers within a network into "sessions" and deliver messages to them individually or as a group. Message delivery is ordered and messages may be selectively sent reliably or unreliably on a message-by-message basis (reliability is very important for some data while avoiding the time and resource overhead of the reliability mechanism is beneficial for others). The reliability mechanism also provides online status so a component will detect when a connection is broken. SDT provides a high degree of fine tuning over the trade-off between latency, reliability levels and resource requirements and availability of large numbers of concurrent sessions means they are a powerful tool for grouping and managing components whose functions are related or whose communication requirements are similar.
https://en.wikipedia.org/wiki?curid=2609179
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For example, as of 2013, there had been interest in the valuation of ecosystem services provided by shellfish production and restoration. A keystone species, low in the food chain, bivalve shellfish such as oysters support a complex community of species by performing a number of functions essential to the diverse array of species that surround them. There is also increasing recognition that some shellfish species may impact or control many ecological processes; so much so that they are included on the list of "ecosystem engineers"—organisms that physically, biologically or chemically modify the environment around them in ways that influence the health of other organisms. Many of the ecological functions and processes performed or affected by shellfish contribute to human well-being by providing a stream of valuable ecosystem services over time by filtering out particulate materials and potentially mitigating water quality issues by controlling excess nutrients in the water.
https://en.wikipedia.org/wiki?curid=1855357
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The exact circumstances under which this sonata, which only survives in the form of a copy made for the Royal College of Music (RCM), was written is unknown. Biographer Jeremy Dibble notes that it may have been written for Richard Gompertz or for Enrique Fernández Arbós, who ultimately became the dedicatee of the composer's Violin Concerto, Op. 74, both colleagues at the RCM. The only known performance of the sonata during the composer's lifetime took place in London on 7 December 1898 at the Prince's Galleries, Piccadilly, under the auspices of the Curtius Club. The soloists for the performance were Australian-born violinist Joseph Kreuse and pianist Viola Fischer-Sobell. John France located several reviews of this concert, most of which were favorable; one exception was the anonymous review published in "The Musical Standard" the day after the concert. The reviewer, while liking the work in general, felt that the finale was too close in character to the preceding movement to be completely effective.
https://en.wikipedia.org/wiki?curid=63307351
2,219,946
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As power reactor technology develops, one goal is to reduce the spent nuclear fuel volume by increasing fuel efficiency and simultaneously reducing down times as much as possible to increase the economic viability of electricity generated from fission-electric stations. To this end, the reactors in the U.S. have doubled their average burn-up rates from 20 to 25 GWd/MTU in the 1970s to over 45 GWd/MTU in the 2000s. Generation III reactors under construction have a designed-for burnup rate in the 60 GWd/tU range and a need to refuel once every 2 years or so. For example, the European Pressurized Reactor has a designed-for 65 GWd/t, and the AP1000 has a designed for average discharge burnup of 52.8 GWd/t and a maximum of 59.5 GWd/t. In-design generation IV reactors will have burnup rates yet higher still.
https://en.wikipedia.org/wiki?curid=11563568
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The first description of magnetotactic bacteria was in 1963 by Salvatore Bellini of the University of Pavia. While observing bog sediments under his microscope, Bellini noticed a group of bacteria that evidently oriented themselves in a unique direction. He realized these microorganisms moved according to the direction of the North Pole, and hence called them "magnetosensitive bacteria". The publications were academic (peer-reviewed by the "Istituto di Microbiologia"s editorial committee under responsibility of the Institute's Director Prof. L. Bianchi, as usual in European universities at the time) and communicated in Italian with English, French and German short summaries in the official journal of a well-known institution, yet unexplainedly seem to have attracted little attention until they were brought to the attention of Richard Frankel in 2007. Frankel translated them into English and the translations were published in the "Chinese Journal of Oceanography and Limnology".
https://en.wikipedia.org/wiki?curid=3382387
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Tsuneko has continued to be involved in different research projects up to this day, mainly investigating different aspects of DNA. She has served as head of laboratories, lead academic supervisor of students, and as a significant intellectual contributor. Specifically, her contributions have been on research done on revealing hGCMa as a placenta-specific transcription regulator, possibly involved in the expression of multiple placenta-specific genes. She contributed to research on the human centromere protein B found to induce translational positioning of nucleosomes on α-satellite sequences. She worked on understanding the genomic regulation of HLA-G and how the presence of a LINE1 gene silencer may explain the limited expression of HLA-G. She also contributed to the research on mice with characteristics of down syndrome in order to understand the genotype-phenotype characteristics of down syndrome in humans.
https://en.wikipedia.org/wiki?curid=4837552
1,215,335
1,558,625
The field of solid-state ionics was first developed in Europe, starting with the work of Michael Faraday on solid electrolytes AgS and PbF in 1834. Fundamental contributions were later made by Walther Nernst, who derived the Nernst equation and detected ionic conduction in heterovalently doped zirconia, which he applied in his Nernst lamp. Another major step forward was the characterization of silver iodide in 1914. Around 1930, the concept of point defects was established by Yakov Frenkel, Walter Schottky and Carl Wagner, including the development of point-defect thermodynamics by Schottky and Wagner; this helped explain ionic and electronic transport in ionic crystals, ion-conducting glasses, polymer electrolytes and nanocomposites. In the late 20th and early 21st centuries, solid-state ionics focused on the synthesis and characterization of novel solid electrolytes and their applications in solid state battery systems, fuel cells and sensors.
https://en.wikipedia.org/wiki?curid=21227565
1,557,740
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Amdahl co-founded Commercial Data Servers in 1996, again in Sunnyvale, and again developing mainframe-like machines but this time with new super-cooled processor designs and aimed at physically smaller systems. One such machine, from 1997, was the ESP/490 (Enterprise Server Platform/490), an enhancement of IBM's P/390 of the System/390 family. Since then, CDS has changed its name and narrowed its focus. As Xbridge Systems, the company now builds software to scan mainframe datasets and database tables for sensitive information such as credit card numbers, social security and other government identification numbers, sensitive medical diagnosis information that can be linked to an individual, and other information such as that needed for electronic discovery.
https://en.wikipedia.org/wiki?curid=247897
1,049,426
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Synaptosomes are commonly used to study synaptic transmission in the test tube because they contain the molecular machinery necessary for the uptake, storage, and release of neurotransmitters. In addition they have become a common tool for drug testing. They maintain a normal membrane potential, contain presynaptic receptors, translocate metabolites and ions, and when depolarized, release multiple neurotransmitters (including acetylcholine, amino acids, catecholamines, and peptides) in a Ca2+-dependent manner. Synaptosomes isolated from the whole brain or certain brain regions are also useful models for studying structure-function relationships in synaptic vesicle release. Synaptosomes can also be isolated from tissues other than brain such as spinal cord, retina, myenteric plexus or the electric ray electric organ. Synaptosomes may be used to isolate postsynaptic densities or the presynaptic active zone with attached synaptic vesicles. Accordingly, various subproteomes of isolated synaptosomes, such as synaptic vesicles, synaptic membranes, or postsynaptic densities can now be studied by proteomic techniques, leading to a deeper understanding of the molecular machinery of brain neurotransmission and neuroplasticity.
https://en.wikipedia.org/wiki?curid=1813940
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In addition to proposed models of inheritance, specific genes have been implicated as factors in fingertip pattern formation (their exact mechanism of influencing patterns is still under research). Multivariate linkage analysis of finger ridge counts on individual fingers revealed linkage to chromosome 5q14.1 specifically for the ring, index, and middle fingers. In mice, variants in the gene EVI1 were correlated with dermatoglyphic patterns. EVI1 expression in humans does not directly influence fingerprint patterns but does affect limb and digit formation which in turn may play a role in influencing fingerprint patterns. Genome-wide association studies found single nucleotide polymorphisms within the gene ADAMTS9-AS2 on 3p14.1, which appeared to have an influence on the whorl pattern on all digits. This gene encodes antisense RNA which may inhibit ADAMTS9, which is expressed in the skin. A model of how genetic variants of ADAMTS9-AS2 directly influence whorl development has not yet been proposed.
https://en.wikipedia.org/wiki?curid=84777
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Peer review is essential to assess and confirm accuracy. "Coordination with peers is necessary...If you think you are right, and the coordinator disagrees, let the assessment reflect that difference of opinion and use a footnote, called a "reclama", inside the U.S. intelligence community if necessary. But never water down your assessment to a lowest common denominator just to obtain coordination. When everyone agrees on an issue, something probably is wrong. "As an example, following the collapse of the Soviet Union, there was an almost unanimous belief that large numbers of Russian ballistic missile specialists would flood into the Third World and aid missile programs in other states (the so-called brain drain)...As it turned out, there was no [expected] mass departure of Russian missile specialists, but Russian expertise was supplied to other states in ways that had been ignored due to the overemphasis on the brain drain.
https://en.wikipedia.org/wiki?curid=4448253
795,136
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Dygerminomas are Malignant germ cell tumor of ovary and particularly prominent in patients diagnosed with gonadal dysgenesis. OGCTs are relatively difficult to detect and diagnose at an early stage because of the nonspecific histological characteristics. Common symptoms of OGCT are bloating, abdominal distention, ascites, and dyspareunia. OGCT is caused mainly due to the formation of malignant cancer cells in the primordial germ cells of the ovary. The exact pathogenesis of OGCTs is still unknown however, various genetic mutations and environmental factors have been identified. OGCTs are commonly found during pregnancy when an adnexal mass is found during a pelvic examination, ultrasound scans show a solid mass in ovary or blood serum test shows elevated alpha-fetoprotein levels. They are unlikely to have metastasized and therefore the standard tumor management is surgical resection, coupled with chemotherapy. The occurrence rate is less than 3% worldwide.
https://en.wikipedia.org/wiki?curid=60324666
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According to the International Union for Conservation of Nature (IUCN), "C.exigua" is considered endangered. This can be attributed to the snail's very niche distribution, and the variety of threats that it is subjected to. One of the major threats listed is the impact of livestock. Due to C.exigua being located near Carnarvon station, a region that was used as a cattle station for over 140 years, faecal matter and waste products from cattle can make their way into waterways, leading to algal blooms and water pollution. Livestock is also known to trample native grasses and degrade the banks of small springs, like the ones "C.exigua" resides in. Creating bores, or digging holes near nearby estuaries, is another threat to C.exigua’s habitat. This has led to multiple springs becoming inactive, due to them altering the flow of water. Similarly, the excavation of local springs will also cause issues, as it erodes the banks of the estuaries, degrading the habitat of many freshwater snail species.
https://en.wikipedia.org/wiki?curid=12656455
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Up until 1992, the Apple Macintosh computers could access only 50 gigabytes of storage at once. This limitation was overcome by a digital video R&D team at the Disney Channel led by Rick Eye. By February 1993, this team had integrated a long-form system that let the Avid Media Composer running on the Apple Macintosh access over seven terabytes of digital video data. With instant access to the shot footage of an entire movie, long-form non-linear editing was now possible. The system made its debut at the NAB conference in 1993 in the booths of the three primary sub-system manufacturers, Avid, Silicon Graphics and Sony. Within a year, thousands of these systems had replaced 35mm film editing equipment in major motion picture studios and TV stations worldwide.
https://en.wikipedia.org/wiki?curid=70729
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Caseids first appear in the fossil record at the end of the Carboniferous and are already present in both North America and Europe with small predatory forms like "Eocasea" and "Datheosaurus". These faunivorous caseids also exist at the beginning of the lower Permian, such as "Callibrachion", and may have existed until the base of the middle Permian with "Phreatophasma". During the Permian, the representatives of the clade mainly evolved towards herbivory. These herbivorous caseids experienced an important evolutionary radiation during the second half of the lower Permian by becoming, with the moradisaurine captorhinid eureptiles, the main herbivores of terrestrial ecosystems instead of edaphosaurids and diadectids. The decline of edaphosaurids and the propagation of caseids coincides with an aridification of the environment that occurred from the Artinskian and which would have favored the caseid expansion. Sedimentological and taphonomic data indicate that the majority of edaphosaurids favored humid habitats (their remains are found mainly in lacustrine and marshy deposits) while herbivorous caseids generally lived in drier biotopes where ponds and streams water were ephemeral. The last caseids date from the Middle Permian and are mainly known in Europe with "Phreatophasma" and "Ennatosaurus" from the Roadian-Wordian of Russia, "Alierasaurus" from the Roadian-(Wordian?) of Sardinia, and "Lalieudorhynchus" from the late Wordian-early Capitanian of southern France. In North America, "Angelosaurus romeri" and "Cotylorhynchus bransoni" from the Chickasha Formation in Oklahoma probably date to the early Roadian, while the caseids from the San Angelo Formation in Texas are slightly older and may straddle the Kungurian-Roadian boundary but it is not yet clear whether they date from the latest Kungurian or from the earliest Roadian.
https://en.wikipedia.org/wiki?curid=4962651
1,381,547
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Bimal Kumar Bachhawat (1925–1996; Kolkata, West Bengal) was an Indian neurochemist and glycobiologist, known for his discovery of HMG-CoA lyase, an intermediate in the mevalonate and ketogenesis pathway, and for the elucidation of the molecular cause of metachromatic leukodystrophy, a hereditary disease of the brain His studies on sugar-bearing liposomes led to its use as a carrier for in situ delivery of drugs and hormones to diseased organs and he pioneered the therapy of systemic fungal infections using liposomal formulations. He was a recipient of several awards including the Shanti Swarup Bhatnagar Award, the highest Indian honor in science and technology and an elected fellow of three major Indian science academies. The Government of India awarded him the third highest civilian honour of the Padma Bhushan, in 1990, for his contributions to science.
https://en.wikipedia.org/wiki?curid=50565963
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The 1961 Formula One season did not officially start until May, eight days after the BRDC race in England. Practice saw Clark crash his Lotus heavily at turn one, and Lotus's woes continued when Innes Ireland crashed in the tunnel during the final session, destroying his car and breaking his leg. Moss took pole in his Rob Walker Lotus with Richie Ginther's Ferrari and Clark's Lotus sharing the front row. Graham and Phil Hill shared the second row. This particular Monaco Grand Prix turned out to be a classic, with one of the greatest driving performances in the history of Formula One by Stirling Moss in a privately entered Lotus against three Ferraris with a lot more power but worse handling than the Lotus.
https://en.wikipedia.org/wiki?curid=1140105
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The Virasoro vertex operator algebras are simple, except when "c" has the form 1–6("p"–"q")/"pq" for coprime integers "p","q" strictly greater than 1 – this follows from Kac's determinant formula. In these exceptional cases, one has a unique maximal ideal, and the corresponding quotient is called a minimal model. When "p" = "q"+1, the vertex algebras are unitary representations of Virasoro, and their modules are known as discrete series representations. They play an important role in conformal field theory in part because they are unusually tractable, and for small "p", they correspond to well-known statistical mechanics systems at criticality, e.g., the Ising model, the tri-critical Ising model, the three-state Potts model, etc. By work of Weiqang Wang concerning fusion rules, we have a full description of the tensor categories of unitary minimal models. For example, when "c"=1/2 (Ising), there are three irreducible modules with lowest "L"-weight 0, 1/2, and 1/16, and its fusion ring is Z["x","y"]/("x"–1, "y"–"x"–1, "xy"–"y").
https://en.wikipedia.org/wiki?curid=1287577
1,090,094
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James E. Boyd, assistant director of Research at the Engineering Experiment Station since 1954, was appointed Director of the station from July 1, 1957, a post in which he served until 1961. While at Tech, Boyd wrote an influential article about the role of research centers at institutes of technology, which argued that research should be integrated with education; he correspondingly involved undergraduates in his research. Under Boyd's purview, the EES gained many electronics-related contracts, to the extent that an Electronics Division was created in 1959; it would focus on radar and communications. The establishment of research facilities was also championed by Boyd. In 1955, Van Leer had appointed Boyd to Georgia Tech's Nuclear Science Committee, which recommended the creation of a Radioisotopes Laboratory Facility and a large research reactor. The $4.5 million ($ million in ) Frank H. Neely Research Reactor would be completed in 1963 and would operate until 1996.
https://en.wikipedia.org/wiki?curid=8753550
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Other than using infinite basis sets, two methods exist to eliminate the BSSE. In the "chemical Hamiltonian approach" (CHA), basis set mixing is prevented "a priori", by replacing the conventional Hamiltonian with one in which all the projector-containing terms that would allow mixing have been removed. In the "counterpoise method" (CP), the BSSE is calculated by re-performing "all" the calculations using the mixed basis sets, and the error is then subtracted "a posteriori" from the uncorrected energy. (The mixed basis sets are realised by introducing "ghost orbitals", basis set functions which have no electrons or protons. It however has been shown that there is an inherent danger in using counterpoise corrected energy surfaces, due to the inconsistent effect of the correction in different areas of the energy surface.) Though conceptually very different, the two methods tend to give similar results. It also has been shown that the error is often larger when using the CP method since the central atoms in the system have much greater freedom to mix with all of the available functions compared to the outer atoms. Whereas in the CHA model, those orbitals have no greater intrinsic freedom and therefore the correction treats all fragments equally. The errors inherent in either BSSE correction disappear more rapidly than the total value of BSSE in larger basis sets.
https://en.wikipedia.org/wiki?curid=4305644
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TRPV6 plays an indispensable role in placental Ca transport. Fetal bone mineralization peaks during late pregnancy. At this stage, fetal blood has a higher concentration of Ca in comparison to maternal blood thereby creating conditions that require active transcellular transport of Ca from mother to the fetus. This process is very important since defects in placental transport of calcium can be precursors for Ca deficiency syndromes and intrauterine growth restrictions. The expression of TRPV6 increases 14-fold during the last 4 days of the murine gestational period and coincides with the peak phase of fetal bone mineralization. The protein TRPV6 is abundantly expressed in the mammalian placental tissues. Indeed, TRPV6 expression is ~1000-fold higher in comparison to TRPV5. In the placenta, TRPV6 is expressed in trophoblasts and syncytiotrophoblasts. In mice, TRPV6 mRNA and protein are expressed in the intraplacental yolk sac and the visceral layer of the extraplacental yolk sac. Most importantly, TRPV6 KO fetuses exhibit a 40% reduction in Ca transport activity and a dramatic decrease in the ash weight (a measure of fetal bone health). In humans, trophoblasts fluid shear stress (FSS) is known to induce a TRPV6-mediated Ca influx and promote microvilli formation through a mechanism involving Ezrin and Akt-phosphorylation.
https://en.wikipedia.org/wiki?curid=4593642
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On February 9, 2011, Tennessee House of Representatives member Bill Dunn introduced House Bill 368, which states that "teachers shall be permitted to help students understand, analyze, critique, and review in an objective manner the scientific strengths and scientific weaknesses of existing scientific theories covered in the course being taught." On February 16, 2011, Tennessee State Senator Bo Watson introduced an identical bill, Senate Bill 893. The House Bill was passed by the House Education Committee on March 29, 2011, and referred to the House Calendar and Rules Committee. Alan I. Leshner, the Chief Executive Officer of the American Association for the Advancement of Science and Executive Publisher of the journal Science, wrote to the House of Representatives opposing the Bill, stating "There is virtually no scientific controversy among the overwhelming majority of researchers on the core facts of global warming and evolution. Asserting that there are significant scientific controversies about the overall nature of these concepts when there are none will only confuse students, not enlighten them."
https://en.wikipedia.org/wiki?curid=20690739
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Martin Wood was educated at Gresham's School, Holt and Trinity College, Cambridge University, where he read engineering, and Imperial College, London. In 1945 he joined the Coal Board as a Bevin Boy for his National Service, working underground at the coal face first in South Wales and later in the Midlands. From 1955 to 1969, he was a Senior Research Officer at the Clarendon Laboratory at the University of Oxford. He used the knowledge he acquired on high field magnets to form Oxford Instruments in 1959, at his home in Northmoor Road, North Oxford. Two years later new superconductors were developed in the USA, and he soon acquired some material and made the first superconducting magnet outside the USA in 1962. Oxford Instruments has since developed these magnets for research and NMR analysis and eventually developed the whole-body superconducting magnets which made possible the development of magnetic resonance imaging.
https://en.wikipedia.org/wiki?curid=2649886
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However, it is important to note that there has been a failure to replicate these results in other countries, such as Germany, Italy and the United States, even when considerable effort has been made to employ identical procedures. Nevertheless, further experiments applied two different methods – namely the placement of fans near the home coop in order to reverse wind direction and usage of deflector lofts to shift the apparent direction of the wind by 90°. Deflector lofts comprised wooden or glass baffles, which deflected wind course and therefore any signature odours. Findings were that pigeons raised in such lofts oriented themselves with a magnitude of a 90° error, known as the ‘deflector loft effect’. The wind reversed experiments, too, exhibited results that favoured the olfactory hypothesis, with experimentals on average flying in the opposing direction of home, while the controls took the correct flight path, when released from the same site.
https://en.wikipedia.org/wiki?curid=25147432
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Hans Asperger described common traits among his patients' family members, especially fathers, and research supports this observation and suggests a genetic contribution to Asperger syndrome. Although no specific genetic factor has yet been identified, multiple factors are believed to play a role in the expression of autism, given the variability in symptoms seen in children. Evidence for a genetic link is that AS tends to run in families where more family members have limited behavioral symptoms similar to AS (for example, some problems with social interaction, or with language and reading skills). Most behavioral genetic research suggests that all autism spectrum disorders have shared genetic mechanisms. There may be shared genes in which particular alleles make an individual vulnerable, and varying combinations result in differing severity and symptoms in each person with AS.
https://en.wikipedia.org/wiki?curid=37556
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The Government Air Ministry ("Reichsluftfahrtministerium") quickly approved the Horten proposal, but ordered the addition of two 30 mm cannons, as they felt the aircraft would also be useful as a fighter due to its estimated top speed being significantly higher than that of any Allied aircraft. German officials assigned the designation "Ho 229" to the aircraft. Göring was reportedly impressed with the design and personally intervened to ensure that three prototypes were ordered at a cost of 500,000 ℛℳ. At one point, the Air Ministry issued an order for 100 production aircraft, although this was subsequently curtailed to only 20 aircraft. Furthermore, as the Horten brothers lacked appropriate production facilities, it was decided that the manufacturing of the aircraft would be handled by an established company, Gothaer Waggonfabrik. This arrangement was somewhat complicated by Gothaer's alleged efforts to persuade German authorities to favour its own projects, which included flying wing designs, over the Ho 229.
https://en.wikipedia.org/wiki?curid=176778
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The nuclear rocket enjoyed strong political support from the influential chairman of the United States Congress Joint Committee on Atomic Energy, Senator Clinton P. Anderson from New Mexico (where LASL was located), and his allies, Senators Howard Cannon from Nevada and Margaret Chase Smith from Maine. This enabled it to survive multiple cancellation attempts that became ever more serious in the cost cutting that prevailed as the Vietnam War escalated and after the space race ended with the Apollo 11 Moon landing. Projects Rover and NERVA were canceled over their objection in January 1973, and none of the reactors ever flew.
https://en.wikipedia.org/wiki?curid=23821416
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By 8 May 2019, protestors at Johns Hopkins University had reached day 35 of a sit-in protest of campus militarization and local police agencies in Garland Hall, restricting access to all faculty and students. Garland Hall, Johns Hopkins University's main administrative hall, was the home location of servers Povey was expected to maintain. According to the university, Povey was denied permission into the building several times prior to 8 May. Led by Povey, counter-protestors entered the building and Povey began removing chains from the doors with a set of bolt cutters. During the chain-removal process, cell-phone footage from the sit-in protestors features a melee between Povey and protestors, as they eventually carry Povey out of the building. Although Povey was adamant that he was the one being attacked in the videos, the university stated that a multitude of Povey's actions, such as leading a group of counter-protestors around campus at 12 am with a set of bolt cutters, threatened the safety of the students and university. Povey would be suspended and ultimately terminated from the university by August 2019.
https://en.wikipedia.org/wiki?curid=67254094
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Enzyme-substrate interactions align the reactive chemical groups and hold them close together in an optimal geometry, which increases the rate of the reaction. This reduces the entropy of the reactants and thus makes addition or transfer reactions less unfavorable, since a reduction in the overall entropy when two reactants become a single product. However this is a general effect and is seen in non-addition or transfer reactions where it occurs due to an increase in the "effective concentration" of the reagents. This is understood when considering how increases in concentration leads to increases in reaction rate: essentially when the reactants are more concentrated, they collide more often and so react more often. In enzyme catalysis, the binding of the reagents to the enzyme restricts the conformational space of the reactants, holding them in the 'proper orientation' and close to each other, so that they collide more frequently, and with the correct geometry, to facilitate the desired reaction. The "effective concentration" is the concentration the reactant would have to be, free in solution, to experiences the same collisional frequency. Often such theoretical effective concentrations are unphysical and impossible to realize in reality - which is a testament to the great catalytic power of many enzymes, with massive rate increases over the uncatalyzed state.
https://en.wikipedia.org/wiki?curid=7137983
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By 1964 it had been demonstrated that regulatory factors extracted from the thymus gland could prevent many of the manifestations of wasting disease. This suggested that the thymus produces substances important in the development of immunity. It was not until 1971 that it was discovered that thymus-derived lymphocytes (T-cells) were important regulators of bone-marrow-derived antibody-producing lymphocytes (B-cells). After the discovery that the thymus was producing profound regulatory factors, several groups of scientists began trying to extract and purify this factor from thymus glands in much the same manner that insulin was prepared from the pancreas for therapeutic use in diabetes. The difficulty was that the thymus is a very small gland and produces very small quantities of the factor. Thus, purification techniques did not allow appropriate pure fractions to be produced in sufficient quantities.
https://en.wikipedia.org/wiki?curid=16033091
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Suckling, Galvin and Schulke assert that in 1990 they discovered the Forest Service was allowing commercial logging within the protected habitat of the owl nests. Speaking to the New York Times in 2010 a spokeswoman for the Forest Service refuted this claim, saying logging “did not occur in these areas” and that owl nests were then given a 100-acre protected area she characterized as “no touch” zones. She implied the CBD co-founders may have been mistaken regarding tree-cutting then occurring in nearby non-protected areas: “other projects did occur and could have included thinning projects to reduce wildland fires, tree plantings or other wildlife projects.” The Forest Service spokeswoman was wrong. Silver had already filed a Petition to List the Mexican Spotted Owl on December 21, 1989 based in part on the fact that at the time 55% of the owls were located in areas the Forest Service had scheduled for cutting. The U.S. Fish and Wildlife concurred that the Forest Service was endangering the owl, listing the owl on March 16, 1993, acknowledging that "[t]here were 316 MTs [management territories] (61 percent) on lands available for timber harvest..."
https://en.wikipedia.org/wiki?curid=8991651
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This technique can be used to study nutrient exchange. The mouse gut microbiome was investigated to determine which microbes fed on host-derived compounds. For this, mice were given food enriched in the stable isotopically labelled amino acids and the microbial biomass examined. NanoSIMS allows for the metabolic contributions of individual microbes to be examined. NanoSIMS was used to study and prove for the first time the nitrogen fixing abilities of bacteria and archaea from the deep ocean by supplying N nitrogen contain compounds to sediment samples. NanoSIMS can also be used to estimate growth rate of organisms, as the amount of carbon or other substrate accumulated inside the cell allows for estimation of how much biomass is being generated.
https://en.wikipedia.org/wiki?curid=45048969
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Lin began his independent career at Cornell University where his group's research has focused on the identification of novel synthetic pathways for medicinally relevant compounds. He focuses on the use of electrochemistry to drive chemical reactions. Electrochemistry can make organic synthesis cheaper and more environmentally friendly. For example, Lin demonstrated an electrochemical approach to synthesize 1,2-diamines from alkenes, which are useful precursors to bioactive natural products, therapeutic agents, and molecular catalysts. More recently, Lin's group has developed a method to directly couple alkyl halides using electrochemistry, providing a promising approach towards this difficult chemical transformation.
https://en.wikipedia.org/wiki?curid=70505581
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Archaeology has been widely influenced by the modern Arab-Israeli conflict. During the British Occupation, many Jewish and Christian populations have renewed their interest in the ancient Judaic archaeological sites located in the region. Several Palestinian authors argue that Zionists, or individuals who believe in a Jewish homeland, use archaeology to create a sense of national identity. One author, in a highly controversial book, when as far as to state that a joint project of the Jewish Palestine Exploration Society and the Va‘adat Shemot (Names Committee) attempted to rename sites from an Arab-Ottoman template to the template of biblical Israel. Today this attitude, is an important factor in the controversy over the West Bank. Judea and Samaria, (the name of the region prior to the occupation of the region by Jordan), are the locations of several archeological sites and ancient Hebrew artifacts. Israeli (and Jewish) scholar Nachman Ben-Yehuda, quoting Y. Shavit, lists the following aspects of archaeology that have been placed in the service of a Jewish homeland: (1) confirming the essence of the biblical narrative; (2) proving the continuity of Jewish settlement in Israel as well as its size; (3) "to emphasize the attitude of Jewish settlers to the land"; (4) emphasizing the practical side of life in the land; (5) providing the contemporary Jewish presence with a deep "structural-historical" meaning; and (6) "to provide the new Jewish presence with concrete symbols from the past which can be transformed into symbols of historical legitimization and presence."
https://en.wikipedia.org/wiki?curid=15703061
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All living cells produce reactive oxygen species (ROS) as a byproduct of metabolism. ROS are reduced oxygen intermediates that include the superoxide radical (O) and the hydroxyl radical (OH•), as well as the non-radical species hydrogen peroxide (HO). These ROS are important in the normal functioning of cells, playing a role in signal transduction and the expression of transcription factors. However, when present in excess, ROS can cause damage to proteins, lipids and DNA by reacting with these biomolecules to modify or destroy their intended function. As an example, the occurrence of ROS have been linked to the aging process in humans, as well as several other diseases including Alzheimer's, rheumatoid arthritis, Parkinson's, and some cancers. Their potential for damage also makes reactive oxygen species useful in direct protection from invading pathogens, as a defense response to physical injury, and as a mechanism for stopping the spread of bacteria and viruses by inducing programmed cell death.
https://en.wikipedia.org/wiki?curid=38173326
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The future studies and questions for activity-dependent plasticity are nearly endless because the implications of the findings will enable many treatments. Despite many gains within the field, there are a wide variety of disorders that further understanding of activity-dependent mechanisms of plasticity would help treat and perhaps cure. These include autism, different severities of intellectual disability, schizophrenia, Parkinson's disease, stress, and stroke. In addition to a better understanding of the various disorders, neurologists should and will look at the plasticity incurred by the immune system, as it will provide great insight into diseases and also give the basis of new immune-centered therapeutics. A better perspective of the cellular mechanisms that regulate neuronal morphology is the next step to discovering new treatments for learning and memory pathological conditions.
https://en.wikipedia.org/wiki?curid=20510214
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The Royal Navy used the 6-pounder extensively in Motor Gun Boats during World War II (especially the Fairmile D). The gun was mounted on a hydraulic-powered mount and fitted with a power loading system developed by the Molins Machine Company Limited, permitting a six-round burst at one round per second. The guns were all the early short-barrel (43 calibre) type and fired exclusively HE (high-explosive) ammunition, at much lower muzzle velocities than for AP (armour-piercing), because of the use of flashless propellant for night operations. The naval designation was QF 6-Pounder Mk IIA; nearly 600 of these weapons were made.
https://en.wikipedia.org/wiki?curid=1834136
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Among the projects inherited by the RAE was a 1943 Navy effort to develop a surface-to-air missiles (SAMs) to shoot down aircraft carrying glide bombs and anti-shipping missiles before they could reach firing range. In March 1944, a panel known as the GAP Committee formed within the MoS to consider this and similar designs from the Army. The group was reformed several times, growing each time as the topic grew more important. From their work the LOPGAP experimental design emerged, short for "Liquid Oxygen and Petrol Guided Anti-aircraft Projectile". Armstrong Whitworth won a contract to develop its liquid-fueled rocket engine.
https://en.wikipedia.org/wiki?curid=2842027
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A silicon atom has fourteen electrons. In the ground state, they are arranged in the electron configuration [Ne]3s3p. Of these, four are valence electrons, occupying the 3s orbital and two of the 3p orbitals. Like the other members of its group, the lighter carbon and the heavier germanium, tin, and lead, it has the same number of valence electrons as valence orbitals: hence, it can complete its octet and obtain the stable noble gas configuration of argon by forming sp hybrid orbitals, forming tetrahedral derivatives where the central silicon atom shares an electron pair with each of the four atoms it is bonded to. The first four ionisation energies of silicon are 786.3, 1576.5, 3228.3, and 4354.4 kJ/mol respectively; these figures are high enough to preclude the possibility of simple cationic chemistry for the element. Following periodic trends, its single-bond covalent radius of 117.6 pm is intermediate between those of carbon (77.2 pm) and germanium (122.3 pm). The hexacoordinate ionic radius of silicon may be considered to be 40 pm, although this must be taken as a purely notional figure given the lack of a simple cation in reality.
https://en.wikipedia.org/wiki?curid=27114
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Circulating tumor cells are found in frequencies on the order of 1-10 CTC per mL of whole blood in patients with metastatic disease. For comparison, a mL of blood contains a few million white blood cells and a billion red blood cells. This low frequency, associated to difficulty of identifying cancerous cells, means that a key component of understanding CTCs biological properties require technologies and approaches capable of isolating 1 CTC per mL of blood, either by enrichment, or better yet with enrichment-free assays that identify all CTC subtypes in sufficiently high definition to satisfy diagnostic pathology image-quantity requirements in patients with a variety of cancer types. To date CTCs have been detected in several epithelial cancers (breast, prostate, lung, and colon) and clinical evidences indicate that patients with metastatic lesions are more likely to have CTCs isolated.
https://en.wikipedia.org/wiki?curid=16806609
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The need for a system like ETCS stems from more and longer running trains resulting from economic integration of the European Union (EU) and the liberalisation of national railway markets. At the beginning of the 1990s there were some national high speed train projects supported by the EU which lacked interoperability of trains. This catalysed the Directive 1996/48 about the interoperability of high-speed trains, followed by Directive 2001/16 extending the concept of interoperability to the conventional rail system. ETCS specifications have become part of, or are referred to, the Technical Specifications for Interoperability (TSI) for (railway) control-command systems, pieces of European legislation managed by the European Union Agency for Railways (ERA). It is a legal requirement that all new, upgraded or renewed tracks and rolling stock in the European railway system should adopt ETCS, possibly keeping legacy systems for backward compatibility. Many networks outside the EU have also adopted ETCS, generally for high-speed rail projects. The main goal of achieving interoperability had mixed success in the beginning.
https://en.wikipedia.org/wiki?curid=2214121
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In 1930, Tomsk State Medical Institute was organized. It was independent institution, a merger of two faculties, Faculty of Medicine and Faculty of Sanitation and Hygiene that separated from Tomsk Imperial University. In 1938–1956, it was known as Medical Institute named after V.M. Molotov. Just before the World War II started, the Institute consisted of 2 faculties, 40 departments and 17 clinics with 700 beds. There was also a blood transfusion station, a vivarium with 1200 laboratory animals, 3 museums, a library with 150 thousand books. All professors, doctors and students were helping soldiers during the War. Some of them went directly to the battlefield, some of them were treating injured in the hospital in Tomsk.
https://en.wikipedia.org/wiki?curid=4575161
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In June 2021, a report revealed that the UB-612 vaccine, developed by the US-based COVAXX, was a for-profit venture initiated by the Blackwater founder Erik Prince. In a series of text messages to Paul Behrends, the close associate recruited for the COVAXX project, Prince described the profit-making possibilities in selling the COVID19 vaccines. COVAXX provided no data from the clinical trials on safety or efficacy it conducted in Taiwan. The responsibility of creating distribution networks was assigned to an Abu Dhabi-based entity, which was mentioned as "Windward Capital" on the COVAXX letterhead but was actually Windward Holdings. The firm's sole shareholder, which handled "professional, scientific and technical activities", was Erik Prince. In March 2021, COVAXX raised $1.35 billion in a private placement.
https://en.wikipedia.org/wiki?curid=63319438
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In addition to its strategic operations, the 96th was occasionally diverted to support ground forces. These missions included bombing coastal defenses, railway bridges, gun emplacements, and field batteries in the battle area prior to and during D-Day in June 1944. It attacked enemy positions to support the breakthrough at Saint-Lô in July 1944 and aided the campaign in France in August by striking roads and road junctions and by dropping supplies to the Maquis. In the early months of 1945, the group struck lines of communications supplying German armies on the western front.
https://en.wikipedia.org/wiki?curid=50883709
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First, Borgmann argues that “there is a problem of orientation in the technologically advanced countries”—“many analysts of the technological society are concerned about the progressive erosion of standards” (79). People, through politics, attempt to address this by “raising the question of values,” however, technology “is never in question” and is always “the means that allow us to realize our preferred values”—the “good life” (80). Borgmann then preemptively answers Marxist critics who would argue for economics over technology as primary in politics, concluding that “the positive goal of the good life that [Marxists] advance is in accord with the dubious promise of technology” (85). In other words, the device paradigm operates on society in an even deeper way than economics, so one must “turn to the examination of liberal democracy to throw light on the ways in which technology has come to rule our lives,” since it is within liberal democracy that technology has typically acquired such power (85).
https://en.wikipedia.org/wiki?curid=29772724
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Mid-ocean ridges are long underwater mountain chains that occur at divergent plate boundaries in the ocean, where new oceanic crust is formed by upwelling mantle material as a result of tectonic plate spreading and relatively shallow (above ~60 km) decompression melting. The upwelling mantle and fresh crust are hotter and less dense than the surrounding crust and mantle, but cool and contract with age until reaching equilibrium with older crust at around 90 Ma. This produces an isostatic response that causes the young regions nearest the plate boundary to rise above older regions and gradually sink with age, producing the mid-ocean ridge morphology. The greater heat at the ridge also weakens rock closer to the surface, raising the boundary between the brittle lithosphere and the weaker, ductile asthenosphere to create a similar elevated and sloped feature underneath the ridge.
https://en.wikipedia.org/wiki?curid=61440570
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The Stentrode, a monolithic stent electrode array, is designed to be delivered via an intravenous catheter under image-guidance to the superior sagittal sinus, in the region which lies adjacent to motor cortex. This proximity to motor cortex underlies the Stentrode's ability to measure neural activity. The procedure is most similar to how venous sinus stents are placed for the treatment of idiopathic intracranial hypertension. The Stentrode communicates neural activity to a battery-less telemetry unit implanted in the chest, which communicates wirelessly with an external telemetry unit capable of power and data transfer. While an endovascular BCI benefits from avoiding craniotomy for insertion, risks such as clotting and venous thrombosis are possible. In pre-clinical animal studies implanted with Stentrode, twenty animals showed no evidence of thrombus formation after 190 days, possibly due to endothelial incorporation of the Stentrode into the vessel wall.
https://en.wikipedia.org/wiki?curid=623686
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The Ministry of Defence investigated a proposal from BAE Systems to adapt the 4.5 inch system to accept the heavier calibre 155 mm (6.1 inch) gun barrel and breech from the AS-90 self-propelled gun. This "155mm Third Generation Maritime Fire Support" (155 TMF) would introduce a common gun calibre for the British Army and Royal Navy, helping with ammunition logistics, and encouraging joint Army-Navy development of extended range and precision guided shells. A £4m contract was awarded to develop a prototype, and firing trials were scheduled for 2009 with delivery in 2014, but the project was cancelled in the cuts implemented following the 2010 Strategic Defence and Security Review.
https://en.wikipedia.org/wiki?curid=8135797
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In 1999, California Polytechnic State University (Cal Poly) professor Jordi Puig-Suari and Bob Twiggs, a professor at Stanford University Space Systems Development Laboratory, developed the CubeSat specifications to promote and develop the skills necessary for the design, manufacture, and testing of small satellites intended for low Earth orbit (LEO) that perform a number of scientific research functions and explore new space technologies. Academia accounted for the majority of CubeSat launches until 2013, when more than half of launches were for non-academic purposes, and by 2014 most newly deployed CubeSats were for commercial or amateur projects.
https://en.wikipedia.org/wiki?curid=641656
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Metallocene initiators are considered as a type of Ziegler-Natta initiators due to the use of the two-component system consisting of a transition metal and a group I-III metal co-initiator (for example methylalumoxane (MAO) or other alkyl aluminum compounds). The metallocene initiators form homogeneous single site catalysts that were initially developed to study the impact that the catalyst structure had on the resulting polymers structure/properties; which was difficult for multi-site heterogeneous Ziegler-Natta initiators. Owing to the discrete single site on the metallocene catalyst researchers were able to tune and relate how the ancillary ligand (those not directly involved in the chemical transformations) structure and the symmetry about the chiral metal center affect the microstructure of the polymer. However, due to chain breaking reactions (mainly Beta-Hydride elimination) very few metallocene based polymerizations are known.
https://en.wikipedia.org/wiki?curid=308682
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In 1983, Boyle simultaneously published two books: "Acid Rain", which highlighted the threat to wildlife and ultimately human health attributed to acid rain "caused by the emission of sulfur dioxide and nitrogen oxides from the combustion of fossil fuels"; and "At the Top of Their Game", a collection of essays about people driven to achieve great things, including profiles of tennis official Jimmy Van Alen, novelist Zane Grey, dog trainer Robert Abady, handballer Jimmy Jacobs, and fly fisherman Charles E. Brooks. Boyle ended his 34-year affiliation with Riverkeeper in 2000, following a dispute with the organization's attorney, Robert F. Kennedy Jr., over Kennedy's hiring of a scientist with a criminal record.
https://en.wikipedia.org/wiki?curid=64533552
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Asimov tried to end the series with "Second Foundation". However, because of the predicted thousand years until the rise of the next Empire (of which only a few hundred had elapsed), the series lacked a sense of closure. For decades, fans pressured him to write a sequel. In 1982, after a 30-year hiatus, Asimov gave in and wrote what was at the time a fourth volume: "Foundation's Edge". This was followed shortly thereafter by "Foundation and Earth". This novel, which takes place some 500 years after Seldon, ties up all the loose ends and ties all his Robot, Empire, and Foundation novels into a single story. He also opens a brand new line of thought in the last dozen pages regarding Galaxia, a galaxy inhabited by a single collective mind. This concept was never explored further. According to his widow Janet Asimov (in her biography of Isaac, "It's Been a Good Life"), he had no idea how to continue after "Foundation and Earth", so he started writing the prequels.
https://en.wikipedia.org/wiki?curid=60133
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The Churchill Machine Tool Co was a founder member of Associated British Machine Tool Makers Ltd (ABMTM) in 1917, an organisation that might be classed as a cartel but which was then perfectly. It was a joint-venture marketing company to develop export markets. Charles Churchill & Co continued to handle domestic sales. A further note of inter-company co-operation was informal Saturday afternoon exchange visits between local machine shops to aid the exchange of ideas and appreciate differences in development and working practice which lasted for a few years before 1923. Companies involved in this included Churchill, Mather & Platt, Hans Renold, John Hetherington, B & S Massey, British Westinghouse and Browett, Lindley & Co of Patricroft. In January 1919, Charles Churchill & Co bought a one-third share in Cornelius Redman & Sons Co Ltd, planer and lathe-makers at Pioneer Works between Parkinson Lane and Warley Road in Halifax, Yorkshire.
https://en.wikipedia.org/wiki?curid=30046818
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There are three ways to place piles for a deep foundation. They can be driven, drilled, or installed by the use of an auger. Driven piles are extended to their necessary depths with the application of external energy in the same way a nail is hammered. There are four typical hammers used to drive such piles: drop hammers, diesel hammers, hydraulic hammers, and air hammers. Drop hammers simply drop a heavy weight onto the pile to drive it, while diesel hammers use a single-cylinder diesel engine to force piles through the Earth. Similarly, hydraulic and air hammers supply energy to piles through hydraulic and air forces. The energy imparted from a hammerhead varies with the type of hammer chosen and can be as high as a million-foot pounds for large scale diesel hammers, a very common hammerhead used in practice. Piles are made of a variety of material including steel, timber, and concrete. Drilled piles are created by first drilling a hole to the appropriate depth, and filling it with concrete. Drilled piles can typically carry more load than driven piles, simply due to a larger diameter pile. The auger method of pile installation is similar to drilled pile installation, but concrete is pumped into the hole as the auger is being removed.
https://en.wikipedia.org/wiki?curid=12306
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Lai and a fellow researcher, Narendra "N. P." Singh, were looking at the effects of nonionizing microwave radiation the same type of radiation emitted by cell phones on the DNA of rats. They used a level of radiation considered safe by government standards and found that the DNA in the brain cells of the rats was damaged—or broken by exposure to the radiation. Lai has stated that cell phones were not subject of concern when he performed the initial studies. Funded initially by the Office of Naval Research, Lai was investigating how radar, which emits radio-frequency radiation, affects the health of operators. “We did not really pay attention to the importance of this thing,” he recalls. But during his research, cell phone company Motorola Inc. indicated that someone had told the company about Lai’s unpublished results. Motorola asked to meet with him in his lab and at a meeting in Copenhagen.
https://en.wikipedia.org/wiki?curid=42031648
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Architectural and engineering design work on changes to LC-39A had begun in 2013, the contract to lease the pad from NASA was signed in April 2014, with construction commencing later in 2014, including the building of a large Horizontal Integration Facility (HIF) in order to house both Falcon 9 and Falcon Heavy launch vehicles with associated hardware and payloads during processing. The first launch occurred on 19 February 2017 with the CRS-10 mission. Crew Access Arm and White Room work still need to be completed before crewed launches with the SpaceX Dragon 2 capsule scheduled for 2019.
https://en.wikipedia.org/wiki?curid=47870562
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Several hearing conservation programs have been developed to educate a variety of audiences about the dangers of NIHL and how to prevent it. Dangerous Decibels aims to significantly reduce the prevalence of noise induced hearing loss and tinnitus through exhibits, education and research. We're hEAR for You is a small non-profit that distributes information and ear plugs at concert and music festival venues. The Buy Quiet program was created to combat occupational noise exposures by promoting the purchase of quieter tools and equipment and encourage manufacturers to design quieter equipment. The National Institute on Deafness and Other Communication Disorders developed the It's a Noisy Planet. Protect their Hearing educational campaign to inform preteens, parents, and educators about the causes and prevention of NIHL. The National Institute for Occupational Safety and Health partnered with the National Hearing Conservation Association in 2007 to establish the Safe-in-Sound Excellence and Innovation in Hearing Loss Prevention Awards to recognize organizations that are successfully implementing hearing loss prevention concepts into their daily routines.
https://en.wikipedia.org/wiki?curid=6894544
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For quantitative measurements, Tc-MDP has some advantages over [F]NaF. MDP renal clearance is not affected by urine flow rate and simplified data analysis can be employed which assumes steady state conditions. It has negligible tracer uptake in red blood cells, therefore correction for plasma to whole blood ratios is not required unlike [F]NaF. However, disadvantages include higher rates of protein binding (from 25% immediately after injection to 70% after 12 hours leading to the measurement of freely available MDP over time), and less diffusibility due to higher molecular weight than [F]NaF, leading to lower capillary permeability.
https://en.wikipedia.org/wiki?curid=2671576
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Birch was born in 1745 or 1746, but where cannot now be traced. He served some years as a surgeon in the army, and afterwards settled in London. He was elected on 12 May 1784 surgeon to St. Thomas's Hospital, and held office till his death. He was also surgeon extraordinary to the prince regent. Birch was a surgeon of much repute in his day, both in hospital and private practice, but was chiefly known for his enthusiastic advocacy of electricity as a remedial agent, and for his equally ardent opposition to the introduction of vaccination. He served the cause of medical electricity by founding an electrical department at St. Thomas's Hospital, and carrying it on with much energy. For more than twenty-one years, he says, he performed the manipulations himself, since he found it difficult to induce the students to take much interest in the subject. The kind of electricity employed was exclusively the frictional, which is now known to be of little use, the therapeutical value of galvanism being not at that time understood. Nevertheless, his writings on the subject, which were widely circulated both in this country and abroad, must have done much in keeping alive professional interest in investigations which have turned out to be remarkably fruitful in practical results.
https://en.wikipedia.org/wiki?curid=68356241
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On 5 January 1916, the winter weather finally improved enough for flying, and Boelcke shot down a British BE.2. Landing near the downed aircraft, he found that the German-speaking pilot knew of him. Boelcke later visited the observer in hospital, bringing him reading material. By now, Boelcke was so well known that this incident was front-page news. On 12 January, Buddecke submitted his ninth combat claim but four had not been verified. Boelcke and Immelmann shot down their eighth victims that day. These two were immediately presented the German Empire's most prestigious decoration, the "Pour le Merite". This award sparked articles in the American and British press, as well as the German news. Boelcke was internationally famous, and could not walk German streets or attend the opera without being lionized. The young lieutenant also found that generals and nobility sought his company.
https://en.wikipedia.org/wiki?curid=193002
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Recently, a new manufacturing process, mnemosynation, was developed at Georgia Tech to enable mass production of crosslinked SMP devices, which would otherwise be cost-prohibitive using traditional thermoset polymerization techniques. Mnemosynation was named for the Greek goddess of memory, Mnemosyne, and is the controlled imparting of memory on an amorphous thermoplastic materials utilizing radiation-induced covalent crosslinking, much like vulcanization imparts recoverable elastomeric behavior on rubbers using sulfur crosslinks. Mnemosynation combines advances in ionizing radiation and tuning the mechanical properties of SMPs to enable traditional plastics processing (extrusion, blow molding, injection molding, resin transfer molding, etc.) and allows thermoset SMPs in complex geometries. The customizable mechanical properties of traditional SMPs are achievable with high throughput plastics processing techniques to enable mass producible plastic products with thermosetting shape-memory properties: low residual strains, tunable recoverable force and adjustable glass transition temperatures.
https://en.wikipedia.org/wiki?curid=9111849
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The continual development of Hydropower has positive effects such as flood control, irrigation, and river navigation; conversely, the development of Hydropower plants can negatively affect the 3 million Laotians relying on the Mekong for livelihood and food security. With dams blocking the migration of fish, many communities will experience a loss of fish population. Over the last few years, the development of hydropower dams have caused a 10-20% population loss while during a period of 2001–2003, the Thai-Lao border showcased a 50% catch decrease, greatly affecting local communities and their livelihood. With the hydrology of the Lower Mekong forcefully altered, agricultural lands will experience a new river regime—variability in its discharge—that can negatively affect farms. The most notable change for the population near the Mekong is the loss of agricultural land due to flooding from hydropower dams. Flooding can cause a loss of crop, productivity, livestock. With an increase of floods near agricultural land there can be a loss of nutrition, an input to the productivity of nearby agriculture.
https://en.wikipedia.org/wiki?curid=36416268
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Thorarchaeota were discovered by analyzing estuary sediments obtained from the White Oak River in North Carolina. Estuaries are brackish bodies of water where fresh and marine water meet, providing a rich and unique area of nutrients. A PhD student at the University of Texas discovered new characteristics of Thorarchaeota that live under sediment and with anoxic properties. The graduate students further proved that the archaea aided in the degradation of organic matter, fixation of inorganic carbon, and the reduction of sulfur. Thorarchaeota genomes that were obtained from the marine appeared to have diversity in metabolic pathways with the potential of degrading and up taking proteins and carbohydrates.
https://en.wikipedia.org/wiki?curid=54594292
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Season 16 of TCEC saw Leela finish in third place in premier division, missing qualification for the superfinal to Stockfish and new deep neural network engine AllieStein. Leela did not suffer any losses in the Premier division, the only engine to do so, and defeated Stockfish in one of the six games they played. However, Leela only managed to score nine wins, while AllieStein and Stockfish both scored 14 wins. This inability to defeat weaker engines led to Leela finishing third, half a point behind AllieStein and a point behind Stockfish. In the fourth TCEC cup, Leela was seeded first as the defending champion, which placed it on the opposite half of the brackets as AllieStein and Stockfish. Leela was able to qualify for the finals, where it faced Stockfish. After seven draws, Stockfish won the eighth game to win the match.
https://en.wikipedia.org/wiki?curid=57597268
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Mitchell's ideas were not popular, with his outspoken opposition to Army and Navy resistance resulting in a court-martial that precipitated his resignation, but he would prove prescient; his 1924 inspection tour of Hawaii and Asia culminated in a report (published in 1925 as the book "Winged Defense") that predicted future war with Japan, including the attack on Pearl Harbor. He would also go on to influence air power advocates such as Russian-American Alexander P. de Seversky, whose 1942 "New York Times" bestselling book, "Victory Through Air Power", was made into a 1943 Walt Disney animated film that opened with a quote from Mitchell; the film is reported to have been influentially shown by Winston Churchill to Franklin D. Roosevelt in support of long-range bombing.
https://en.wikipedia.org/wiki?curid=537478
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The cost itself may be a disadvantage. Schools and districts in areas with low incomes and high rates of homelessness have argued that Chromebook programs compare positively to paper for homework return-rates. Other disadvantages may be related to the sustainability of infrastructure. Currently the cost of the sum of all replacement parts for one Chromebook exceeds the cost of a Chromebook gained through a school districts bulk discount. This has resulted in school districts transitioning from a traditional repair model to treating Chromebooks as a disposable device. Another disadvantage is the need to future proof reliability. Up until recently, and prior to improvements in battery technology, laptops mainly served as non portable devices. Many component issues such as battery and cabling issues related to laptops have trickled down into the Chromebook model. This is an issue due to Chromebooks typically being distributed in far greater numbers. This risks an interruption to instruction that needs to be overcome.
https://en.wikipedia.org/wiki?curid=6357454
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1st phase of training begins with a unified 2-year pre-clinical training for dentists and physicians. Problem-based learning (PBL) is employed depending on the university. 3rd year autumn consists of clinico-theoretical phase in pathology, genetics, radiology and public health and is partially combined with physicians' 2nd phase. 3rd phase clinical training lasts for the remaining 3 years and includes periods of being on call at University Central Hospital Trauma Centre, Clinic of Oral and Maxillofacial Diseases and at the Children's clinic. Candidates who successfully complete the 4th year of training qualify for a paid summer rotation in a Community health center of their choice. Annual intake of dentists into Faculties of Medicine is a national total 160 students.
https://en.wikipedia.org/wiki?curid=8978514
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ATI Technologies Inc. (commonly called ATI) was a Canadian semiconductor technology corporation based in Markham, Ontario, that specialized in the development of graphics processing units and chipsets. Founded in 1985 as Array Technology Inc., the company listed publicly in 1993. Advanced Micro Devices (AMD) acquired ATI in 2006. As a major fabrication-less or fabless semiconductor company, ATI conducted research and development in-house and outsourced the manufacturing and assembly of its products. With the decline and eventual bankruptcy of 3dfx in 2000, ATI and its chief rival Nvidia emerged as the two dominant players in the graphics processors industry, eventually forcing other manufacturers into niche roles.
https://en.wikipedia.org/wiki?curid=177421
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Given the opposing properties of the IgG subclasses (fixing and failing to fix complement; binding and failing to bind FcR), and the fact that the immune response to most antigens includes a mix of all four subclasses, it has been difficult to understand how IgG subclasses can work together to provide protective immunity. In 2013, the Temporal Model of human IgE and IgG function was proposed.<ref name="10/16/2013"></ref> This model suggests that IgG3 (and IgE) appear early in a response. The IgG3, though of relatively low affinity, allows IgG-mediated defences to join IgM-mediated defences in clearing foreign antigens. Subsequently, higher affinity IgG1 and IgG2 are produced. The relative balance of these subclasses, in any immune complexes that form, helps determine the strength of the inflammatory processes that follow. Finally, if antigen persists, high affinity IgG4 is produced, which dampens down inflammation by helping to curtail FcR-mediated processes.
https://en.wikipedia.org/wiki?curid=490666
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DSCS II was a major step forward in communications satellite design, with both broad area and narrow beam coverage. The first two satellites were launched from a Titan IIIC on 2 November 1971, placing one over the Atlantic Ocean and one over the Pacific Ocean. After redesigning due to failures in the initial tranche, the second set of satellites was launched on 13 December 1973 and the constellation was declared operational by the Defense Communications Agency in February 1974 with only two satellites on orbit. The third launch on 20 May 1975 had an anomaly in the Titan IIIC's guidance system which resulted in the spacecraft reentering the atmosphere and the DSCS II satellites were lost. The constellation was later completed, and by the 1980s DSCS II provided strategic communications through 46 ground terminals, the Diplomatic Telecommunications Service' 52 terminals, and the Ground Mobile Forces 31 tactical terminals. The last DSCS II satellite was decommissioned on 13 December 1993, however design of the Defense Satellite Communications System Phase III (DSCS III) began in 1974.
https://en.wikipedia.org/wiki?curid=66185637
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The admissions to all the B.Tech programmes offered at Amrita Schools of Engineering is done through Amrita Engineering Entrance Examinaton (AEEE) and JEE Main. While 60% of the seats are reserved for AEEE candidates, the rest are allotted for students applying with their JEE Main (BE/BTech) common rank. Admission for foreign nationals, NRI and PIO students is through SAT. The candidates based on their ranks are invited for counselling at any of the campuses, where they are allowed to choose branch and campus available, and book their seats. The candidate must have completed Class 12 or HSE or equivalent from recognized Board or University with compulsory subjects of English, Mathematics, Physics and any one of the technical subject prescribed by AICTE with minimum 60% aggregate to be eligible to apply for AEEE. The age of the candidate should be less than 21 years at the time of Admission.
https://en.wikipedia.org/wiki?curid=61394843
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Aristotle saw a distinction between "natural motion" and "forced motion", and he believed that 'in a void' i.e.vacuum, a body at rest will remain at rest and a body in motion will continue to have the same motion. In this way, Aristotle was the first to approach something similar to the law of inertia. However, he believed a vacuum would be impossible because the surrounding air would rush in to fill it immediately. He also believed that an object would stop moving in an unnatural direction once the applied forces were removed. Later Aristotelians developed an elaborate explanation for why an arrow continues to fly through the air after it has left the bow, proposing that an arrow creates a vacuum in its wake, into which air rushes, pushing it from behind. Aristotle's beliefs were influenced by Plato's teachings on the perfection of the circular uniform motions of the heavens. As a result, he conceived of a natural order in which the motions of the heavens were necessarily perfect, in contrast to the terrestrial world of changing elements, where individuals come to be and pass away.
https://en.wikipedia.org/wiki?curid=3114255
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The 1835 edition of the Catholic "List of Prohibited Books" for the first time omits the "Dialogue" from the list. In his 1921 papal encyclical, "In praeclara summorum", Pope Benedict XV stated that, "though this Earth on which we live may not be the center of the universe as at one time was thought, it was the scene of the original happiness of our first ancestors, witness of their unhappy fall, as too of the Redemption of mankind through the Passion and Death of Jesus Christ". In 1965 the Second Vatican Council stated that, "Consequently, we cannot but deplore certain habits of mind, which are sometimes found too among Christians, which do not sufficiently attend to the rightful independence of science and which, from the arguments and controversies they spark, lead many minds to conclude that faith and science are mutually opposed." The footnote on this statement is to Msgr. Pio Paschini's, "Vita e opere di Galileo Galilei", 2 volumes, Vatican Press (1964). Pope John Paul II regretted the treatment which Galileo received, in a speech to the Pontifical Academy of Sciences in 1992. The Pope declared the incident to be based on a "tragic mutual miscomprehension". He further stated:
https://en.wikipedia.org/wiki?curid=83754
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Mary Spio is a Ghanaian astronautical engineer and entrepreneur. After being born and raised in Ghana, Spio pursued a bachelor's degree in electrical engineering at Syracuse University in New York, and a master's in electrical engineering at the Georgia Institute of Technology. Throughout her career, she served in the United States Air Force, worked on a NASA project, contributed innovations to companies like Microsoft Xbox, and became the head of satellite systems at Boeing. She also founded her own company CEEK Virtual Reality with the mission to make Virtual Reality more accessible. Spio is also a renowned author with publications such as “It's Not Rocket Science: 7 Game-Changing Traits for Achieving Uncommon Success”.
https://en.wikipedia.org/wiki?curid=57218855
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In 2015, "Argonne" a team led by Dr. Anirudha Sumant have been able to experimentally demonstrate superlubricity at true microscale for the first time [8]. The detailed experimental investigations were supported by sophisticated computational studies. Argonne scientists used Mira [supercomputer] simulating up to 1.2 million atoms for dry environments and up to 10 million atoms for humid environments [8] The researchers used the LAMMPS (Large-scale Atomic/Molecular Massively Parallel Simulator) code to carry out the computationally demanding reactive molecular dynamics simulations. This team optimized LAMMPS and its implementation of ReaxFF by adding OpenMP threading, replacing MPI point-to-point communication with MPI collectives in key algorithms, and leveraging MPI I/O. Altogether, these enhancements allowed the code to perform twice as fast as before.
https://en.wikipedia.org/wiki?curid=592513
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By the late 1980s, DC-10 and L-1011 models were approaching retirement age, prompting manufacturers to develop replacement designs. McDonnell Douglas started working on the MD-11, a stretched and upgraded successor of the DC-10. Airbus, thanks to the success of its A320 family, developed the medium-range A330 twinjet and the related long-range A340 quad-jet. In 1988, Boeing began developing what would be the 777 twinjet, using the twin-engine configuration given past design successes, projected engine developments, and reduced-cost benefits. In addition, Boeing also released a major update on their 747, the 747-400.
https://en.wikipedia.org/wiki?curid=254128
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One solution to MIDI timing problems is to mark MIDI events with the times they are to be played, and store them in a buffer in the MIDI interface ahead of time. Sending data beforehand reduces the likelihood that a busy passage can send a large amount of information that overwhelms the transmission link. Once stored in the interface, the information is no longer subject to timing issues associated with USB jitter and computer operating system interrupts, and can be transmitted with a high degree of accuracy. MIDI timestamping only works when both hardware and software support it. MOTU's MTS, eMagic's AMT, and Steinberg's Midex 8 had implementations that were incompatible with each other, and required users to own software and hardware manufactured by the same company to work. Timestamping is built into FireWire MIDI interfaces, Mac OS X Core Audio, and Linux ALSA Sequencer.
https://en.wikipedia.org/wiki?curid=19996
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Currently, there are regulations pertaining to the collection of patient data. This includes policies such as the Health Insurance Portability and Accountability Act (HIPAA) and the European General Data Protection Regulation (GDPR). The GDPR pertains to patients within the EU and details the consent requirements for patient data use when entities collect patient healthcare data. Similarly, HIPAA protects healthcare data from patient records in the United States. In May 2016, the White House announced its plan to host a series of workshops and formation of the National Science and Technology Council (NSTC) Subcommittee on Machine Learning and Artificial Intelligence. In October 2016, the group published The National Artificial Intelligence Research and Development Strategic Plan, outlining its proposed priorities for Federally-funded AI research and development (within government and academia). The report notes a strategic R&D plan for the subfield of health information technology is in development stages.
https://en.wikipedia.org/wiki?curid=52588198
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The ways in which options and attributes are grouped influence the choices that are made. Examples of such partitioning of options include the division of a household budget into categories (e.g. rent, food, utilities, transportation etc.), or categories of investments within a portfolio (e.g. real estate, stocks, bonds, etc.), while examples of partitioning attributes include the manner in which attributes are grouped together for example a label may group several related attributes together (e.g. convenient) or list them individually (e.g. short running time, little cleanup, low maintenance). The number and type of these categories is important because individuals have a tendency to allocate scarce resources equally across them. People tend to divide investments over the options listed in 401K plans they favor equal allocation of resources and costs across individuals (all else being equal), and are biased to assign equal probabilities to all events that could occur. As a result, aggregate consumption can be changed by the number and types of categorizations. For instance, car buyers can be nudged toward more responsible purchases by itemizing practical attributes (gas mileage, safety, warranty etc.) and aggregating less practical attributes (i.e. speed, radio, and design are grouped together as "stylishness").
https://en.wikipedia.org/wiki?curid=20502327
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Many times the organism that has "escaped" continuously undergoes selective pressure because the predator it has escaped from evolves to create another adaptation in response, causing the process to continue. These "offensive" traits developed by predators range widely. For example, herbivores can develop an adaptation that allows for improved detoxification which allow to overcome plant defenses, thus causing escape and radiate coevolution to continue. Often the term "evolutionary arms race" is used to illustrate the idea that continuous evolution is needed to maintain the same relative fitness while the two species are coevolving. This idea also ties in with the Red Queen hypothesis. Counter adaptations among two organisms through escape and radiate coevolution is a major driving force behind diversity.
https://en.wikipedia.org/wiki?curid=40745870
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In the 19th century, the prevailing scientific view on the source of the Sun's heat was that it was generated by gravitational contraction. In the 1840s, astronomers J. R. Mayer and J. J. Waterson first proposed that the Sun's massive weight would cause it to collapse in on itself, generating heat. Both Hermann von Helmholtz and Lord Kelvin expounded upon this idea in 1854, suggesting that heat may also be produced by the impact of meteors on the Sun's surface. Theories at the time suggested that stars evolved moving down the main sequence of the Hertzsprung-Russell diagram, starting as diffuse red supergiants before contracting and heating to become blue main-sequence stars, then even further down to red dwarfs before finally ending up as cool, dense black dwarfs. However, the Sun only has enough gravitational potential energy to power its luminosity by this mechanism for about 30 million years—far less than the age of the Earth. (This collapse time is known as the Kelvin–Helmholtz timescale.)
https://en.wikipedia.org/wiki?curid=17052696
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As lead author of a paper produced in 1998 with co-authors Raymond S. Bradley and Malcolm K. Hughes, Mann used advanced statistical techniques to find regional variations in a hemispherical climate reconstruction covering the past 600 years. In 1999 the same team used these techniques to produce a reconstruction over the past 1,000 years (MBH99), which was dubbed the "hockey stick graph" because of its shape. He was one of eight lead authors of the "Observed Climate Variability and Change" chapter of the Intergovernmental Panel on Climate Change (IPCC) Third Scientific Assessment Report published in 2001. A graph based on the MBH99 paper was highlighted in several parts of the report and was given wide publicity. The IPCC acknowledged that his work, along with that of the many other lead authors and review editors, contributed to the award of the 2007 Nobel Peace Prize, which was won jointly by the IPCC and Al Gore.
https://en.wikipedia.org/wiki?curid=345811
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Operational Medicine is the field of Army medicine that provides medical support to the soldier and his/her Chain of Command. Many operational physicians serve as Division, Brigade and Battalion level surgeons (the word "surgeon" is used to identify a physician that is assigned to a unit as a primary care provider and not necessarily as a General Surgeon). These physicians are either assigned through the "PROFIS" system or through permanent assignment (PCS). Deployments with units to combat theaters are for the duration of a deployment and the jobs are mostly filled by primary care physicians. A PROFIS provider can expect to be deployed away from their family for a total of 16 months (1 month before deployment, 12 months in theater, and 3 months for "stabilization" after return to the assigned units home station). This means that primary care physicians are deployed for longer periods than most "specialist physicians". A specialist (i.e. General Surgeon, Pulmonologist, Cardiologist, Trauma Surgeon, Rheumatologist) are usually deployed for 6 months. Operational Physicians should expect that more than 60% of their time will be spent in administrative roles and non-patient care. 40% of the operational providers time is spent caring for soldiers or supervising unit Physician Assistants (PA). With the recent Brigade Combat Team (BCT) restructuring, the demand for operational surgeons have increased. It is possible that the low retention rates of Captains and junior Major rank Physicians in the primary care fields are due to the discrepancies in deployment length and deployment frequency between primary care and specialty physicians.
https://en.wikipedia.org/wiki?curid=2344754
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Manga stories are typically printed in black-and-white—due to time constraints, artistic reasons (as coloring could lessen the impact of the artwork) and to keep printing costs low—although some full-color manga exist (e.g., "Colorful"). In Japan, manga are usually serialized in large manga magazines, often containing many stories, each presented in a single episode to be continued in the next issue. Collected chapters are usually republished in "tankōbon" volumes, frequently but not exclusively paperback books. A manga artist ("mangaka" in Japanese) typically works with a few assistants in a small studio and is associated with a creative editor from a commercial publishing company. If a manga series is popular enough, it may be animated after or during its run. Sometimes, manga are based on previous live-action or animated films.
https://en.wikipedia.org/wiki?curid=18985
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In an experiment in 2006, "P. clarus" showed promise for controlling the fourlined plant bug, "Poecilocapsus lineatus", which severely damages sweet basil, "Ocimum basilicum", a herb commercially grown in greenhouses. The potential advantages of "P. clarus" for biocontrol include: it prefers to stay overnight in the same nest, it is able to detects prey visually from a distance, is able to take a wide range of prey, it can both wait for prey and hunt actively, it is able to learn and recognize particular prey, and can it can be reared in individual cages. Although cannibalism is likely to prevent mass rearing of "P. clarus", it is possible to collect egg sacs or spiders and move them to where they are needed. In the breeding season, one mated female can lay well over 100 eggs per sac, many females lay more than one egg sac, and it is easy to recognize the egg sacs. Juvenile and adult jumping spiders can be collected via sweep netting or by providing good sites for nests, even in plumber's tubing placed in old fields.
https://en.wikipedia.org/wiki?curid=31578101
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The Triangle Universities Nuclear Laboratory was established in 1965, with a $2.5 Million grant from the United States Atomic Energy Commission providing the funding for a new 15 MeV Tandem Van de Graaff accelerator as well as a 15 MeV Cyclotron. After three years of construction and testing, the new accelerator facility became operational in December 1968. Henry Newson, a nuclear physics professor at Duke University, was responsible for the proposal, was the original proponent of combining the efforts of the three universities, and served as the first director of the new laboratory. The Tandem Generator and the Cyclotron at TUNL were combined into what was named a Cyclo-Graaff accelerator. Ions would first be accelerated in the Cyclotron. Then, once the initial energy was high enough, the beam from the cyclotron would be injected into the Tandem Generator where it would be further accelerated. Using the accelerators together effectively doubled the maximum energy that the lab could reach when compared to the energies of each individual accelerator. This combination, the Cyclo-Graaff, would be used by Henry Newson to study Nuclear Structure until his death in 1978.
https://en.wikipedia.org/wiki?curid=11622604
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Because of the possibility of writing non-terminating programs, Turing-complete models of computation (such as languages with arbitrary recursive functions) must be interpreted with care, as naive application of the correspondence leads to an inconsistent logic. The best way of dealing with arbitrary computation from a logical point of view is still an actively debated research question, but one popular approach is based on using monads to segregate provably terminating from potentially non-terminating code (an approach that also generalizes to much richer models of computation, and is itself related to modal logic by a natural extension of the Curry–Howard isomorphism). A more radical approach, advocated by total functional programming, is to eliminate unrestricted recursion (and forgo Turing completeness, although still retaining high computational complexity), using more controlled corecursion wherever non-terminating behavior is actually desired.
https://en.wikipedia.org/wiki?curid=254299
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Applying the Titius–Bode law to the Earth–Moon system, which he generalizes to aether, Allais calculates a "wind" of 7.95 km/s, which is comparable to the values found by the experiments of Michelson and Miller. Hence Allais deduces that the aether turns with the stars, as proposed by the aether drag hypothesis, and is not fixed as Hendrik Lorentz thought when inventing his famous transformation and his ether theory. But the majority of scientists at the end of the 19th century imagined that such an aether crossed the Earth so that the rotation of the Earth around the Sun would cause an important variation of 30 km/s. Consequently, since the third postulate on which special relativity is based is the constancy of the speed of light in a vacuum, Allais considers it unfounded. In order to measure a change in the speed of light, one would have to get back to the definition of the 1960 meter, since confidence in the theory of relativity nowadays is such that current metrology uses constancy of the speed of light as an axiom.
https://en.wikipedia.org/wiki?curid=915997
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The approximation in the FPM can be summarized as follows. For each point formula_1 in the analysis domain formula_2 ("star point"), an approximated solution is locally constructed by using a subset of surrounding supporting points formula_3, which belong to the problem domain ("local cloud of points" formula_4). The approximation is computed as a linear combination of the cloud unknown nodal values (or parameters) and certain metric coefficients. These are obtained by solving a WLSQ problem at the cloud level, in which the distances between the nodal parameters and the approximated solution are minimized in a LSQ sense. Once the approximation metric coefficients are known, the problem governing PDEs are sampled at each "star point" by using a collocation method. The continuous variables (and their derivatives) are replaced in the sampled equations by the discrete approximated forms, and the solution of the resulting system allows calculating the unknown nodal values. Hence, the approximated solution satisfying the governing equations of the problem can be obtained. It is important to note that the highly local character of the FPM makes the method suitable for implementing efficient parallel solution schemes.
https://en.wikipedia.org/wiki?curid=50991882
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In the case of bipartite graphs or multigraphs with maximum degree , the optimal number of colors is exactly . showed that an optimal edge coloring of these graphs can be found in the near-linear time bound , where is the number of edges in the graph; simpler, but somewhat slower, algorithms are described by and . The algorithm of begins by making the input graph regular, without increasing its degree or significantly increasing its size, by merging pairs of vertices that belong to the same side of the bipartition and then adding a small number of additional vertices and edges. Then, if the degree is odd, Alon finds a single perfect matching in near-linear time, assigns it a color, and removes it from the graph, causing the degree to become even. Finally, Alon applies an observation of , that selecting alternating subsets of edges in an Euler tour of the graph partitions it into two regular subgraphs, to split the edge coloring problem into two smaller subproblems, and his algorithm solves the two subproblems recursively. The total time for his algorithm is .
https://en.wikipedia.org/wiki?curid=690647
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In March 2015 Tesla Motors announced that it will introduce its Autopilot technology by mid 2015 through a software update for the cars equipped with the systems that allow autonomous driving. Some industry experts have raised questions about the legal status of autonomous driving in the U.S. and whether Model S owner would violate current state regulations when using the autopilot function. The few states that have passed laws allowing autonomous cars on the road limit their use for testing purposes, not the use by the general public. Also, there are questions about the liability for autonomous cars in case there is a mistake. A Tesla spokesman said there is: Google's director of self-driving cars at the company said he does not think there is a regulatory block as far as the self-driving vehicle met crash-test and other safety standards. A spokesman for the National Highway Traffic Safety Administration (NHTSA) said that ""any autonomous vehicle would need to meet applicable federal motor vehicle safety standards"" and the NHTSA ""will have the appropriate policies and regulations in place to ensure the safety of this type of vehicles"."
https://en.wikipedia.org/wiki?curid=44787757
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Begun in 1995 under the vision of its founder Pakistani Ex-Prime Minister Benazir Bhutto and led by Dr. Javaid Laghari as its first president and project director, SZABIST is honored and named in remembrance of Shaheed Zulfiqar Ali Bhutto. Financial endowment and research funding are coordinated by the leadership of the Pakistan Peoples Party. The university offers undergraduate and post-graduate degrees. It is a member of the Association of Commonwealth Universities of the United Kingdom and the Association to Advance Collegiate Schools of Business, as well as other international education associations. SZABIST is regarded as one of the more notable private research institutions of higher learning in Pakistan and ranked among the nation's top-ten institutions by the Higher Education Commission, as of 2013.
https://en.wikipedia.org/wiki?curid=30855965
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Several new types were developed; the Royal Aircraft Factory offered its R.E.8 design and Armstrong Whitworth produced the design that eventually emerged as the F.K.8. In March 1916, Frank Barnwell of the Bristol Aeroplane Company, commenced work on a replacement for the B.E.2. This initially took two forms, the Type 9 R.2A, to be powered by the 120 hp Beardmore engine and the similar Type 9A R.2B, powered by the 150 hp Hispano-Suiza. Both designs had the fuselage mounted between the wings, with a gap between the lower longerons and the wing, along with a substantial part of the fin beneath the fuselage. These features were intended to improve the field of fire for the observer; the positioning of the fuselage also resulted in the upper wing obscuring less of the pilot's field of view. The crew positions were placed as close together as possible, to help communication between the pilot and observer.
https://en.wikipedia.org/wiki?curid=946746
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After missing out on the 2009 Tournament, BC returned in 2010 as a number one seed. The Eagles defeated Alaska and Yale in the Northeast Regional in Worcester, earning them a berth in the Frozen Four to be played at Ford Field in Detroit. BC defeated Miami (OH) 7–1 in the national semifinal, the fourth time in five years that the Eagles ended the RedHawks' season in the NCAA Tournament. BC would face Wisconsin in the championship, a rematch of the 2006 title game. The Eagles avenged that loss by defeating the Badgers 5-0 behind a two-goal effort from sophomore Cam Atkinson and an MVP performance by senior Ben Smith, who would be named the Frozen Four's Most Outstanding Player. Junior John Muse became just the fourth goalie to record a shutout in a title game. The game was played before a record crowd of 37,592, the largest to attend an indoor hockey game.
https://en.wikipedia.org/wiki?curid=18880361
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On August 30, NASA presented plans to award three feasibility study contracts for the Apollo spacecraft, conceived as a three-man Earth orbital and circumlunar craft, with growth potential for crewed lunar landings. A Request For Proposal was issued on September 12, and fourteen bids were received by October 9. On October 25, NASA awarded the $250,000, six-month contracts to General Dynamics/Convair, General Electric, and the Glenn L. Martin Company. Meanwhile, members of the Space Task Group performed their own spacecraft design studies, to serve as a gauge to judge and monitor the three industry designs.
https://en.wikipedia.org/wiki?curid=36082139
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Development was complicated by the diversity of platforms the Mauler system was to be installed upon. A compatible identification friend or foe system (IFF) was a particular problem. Development of the missile airframe and engine progressed rapidly. Unguided examples, known as "Launch Test Vehicles", started firing tests in September 1961. These were quickly followed by the "Control Test Vehicle" guided examples in 1961, which flew simple paths to test the aerodynamic controls. Both test series demonstrated a variety of problems, including failures of the rocket casings, and excessive drag and wing flutter. A competing system with the British and potentially other NATO states was the PT.428 which eventually developed successfully into the Rapier missile.
https://en.wikipedia.org/wiki?curid=19633685
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Indirect interventions may help reduce community transmission and prevent outbreaks. These interventions include reducing the density at which salmon are farmed, establishing fallowing periods for farms affected by piscirickettsiosis, and disinfecting equipment between production cycles. Since 2009, the Chilean salmon farming industry has adopted practices such as mandatory fallowing and equipment disinfection and it has been prohibited to transfer fish between different farms; these strategies have reduced the likelihood of farm-to-farm transmission, but the disease is still prevalent. Salmon farming companies are also required to submit information about infectious diseases to the Chilean government to maintain their licenses. The length of the fallowing period and the disinfectants used on equipment may be important. Fallowing for at least three months can help lower the abundance of "P. salmonis" between production cycles, although it does not eliminate the bacteria completely. Peracetic acid, peroxides, and active and inactive chlorine dioxides are the most effective sanitizers at reducing "P. salmonis" prevalence.
https://en.wikipedia.org/wiki?curid=40421553
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As with any experimental design, the CCCS design has limitations. When the sample in the series is drawn from a particular clinic, there is the potential that that sample may not be representative of the broader population because of referral bias. One additional limitation of reporting on a series of cases receiving clinical treatment (as opposed to participants enrolled in a formal research protocol) is that there tend to be variations in how the treatment is applied across participants. This is particularly the case with behavioral interventions which are individualized, and continuously evaluated, and altered based on the individual’s response. An ideal middle ground would involve the use of treatment algorithms to structure how treatment components are sequenced while still preserving the response-guided approach that is the hallmark of good clinical practice in applied behavior.
https://en.wikipedia.org/wiki?curid=50425977
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