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The university is composed of complementary rural and urban campuses. In December 2016, UGHE began construction on the 250-acre Butaro academic campus, which is embedded in a rural primary health care delivery system. The first phase of the campus opened in 2018 with classrooms, administrative buildings, a library, and dorms. The urban campus will be located in Masaka Sector, Kicukiro District in the Rwandan capital of Kigali, the heart of a planned “medical city”. In addition to leveraging two existing clinical facilities – Butaro Hospital and Masaka Hospital in Kigali – UGHE will utilize PIH-supported sites across Rwanda to enable a breadth of educational opportunities in clinical and delivery settings. These campuses were designed by MASS Design and Shepley Bulfinch, one of the oldest architecture firms in continuous practice in the United States.
https://en.wikipedia.org/wiki?curid=51997162
1,658,141
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Bromeliads often serve as phytotelmata, accumulating water between their leaves. One study found 175,000 bromeliads per hectare (2.5 acres) in one forest; that many bromeliads can sequester 50,000 liters (more than 13,000 gallons) of water. The aquatic habitat created as a result is host to a diverse array of invertebrates, especially aquatic insect larvae, including those of mosquitos. These bromeliad invertebrates benefit their hosts by increasing nitrogen uptake into the plant. A study of 209 plants from the Yasuní Scientific Reserve in Ecuador identified 11,219 animals, representing more than 350 distinct species, many of which are found only on bromeliads. Examples include some species of ostracods, small salamanders about in length, and tree frogs. Jamaican bromeliads are home to "Metopaulias depressus", a reddish-brown crab across, which has evolved social behavior to protect its young from predation by "Diceratobasis macrogaster", a species of damselfly whose larvae live in bromeliads. Some bromeliads even form homes for other species of bromeliads.
https://en.wikipedia.org/wiki?curid=58041
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In nature, there is a wide array of biominerals, ranging from iron oxide to strontium sulfate, with calcareous biominerals being particularly notable. However, the most taxonomically widespread biomineral is silica (SiO·nHO), being present in all eukaryotic supergroups. Notwithstanding, the degree of silicification can vary even between closely related taxa, from being found in composite structures with other biominerals (e.g., limpet teeth; to forming minor structures (e.g., ciliate granules; or being a major structural constituent of the organism. The most extreme degree of silicification is evident in the diatoms, where almost all species have an obligate requirement for silicon to complete cell wall formation and cell division. Biogeochemically and ecologically, diatoms are the most important silicifiers in modern marine ecosystems, with radiolarians (polycystine and phaeodarian rhizarians), silicoflagellates (dictyochophyte and chrysophyte stramenopiles), and sponges with prominent roles as well. In contrast, the major silicifiers in terrestrial ecosystems are the land plants (embryophytes), with other silicifying groups (e.g., testate amoebae) having a minor role.
https://en.wikipedia.org/wiki?curid=1984187
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Although most code output by Copilot can be classified as a transformative work, GitHub admits that a small proportion is copied verbatim, which has led to fears that the output code is insufficiently transformative to be classified as fair use and may infringe on the copyright of the original owner. This leaves Copilot on untested legal ground, although GitHub states that "training machine learning models on publicly available data is considered fair use across the machine learning community". The company has also stated that as of June 2022 only a few source codes are taken over completely or partially unchanged. Therefore as the software continues to learn, this figure is expected to drop. Also in June 2022, the Software Freedom Conservancy announced it would end all uses of GitHub in its own projects, accusing Copilot of ignoring code licenses used in training data. In November 2022, a class-action lawsuit was filed, challenging the legality of Copilot.
https://en.wikipedia.org/wiki?curid=68172268
206,121
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Early research on the role of antioxidants in biology focused on their use in preventing the oxidation of unsaturated fats, which is the cause of rancidity. Antioxidant activity could be measured simply by placing the fat in a closed container with oxygen and measuring the rate of oxygen consumption. However, it was the identification of vitamins C and E as antioxidants that revolutionized the field and led to the realization of the importance of antioxidants in the biochemistry of living organisms. The possible mechanisms of action of antioxidants were first explored when it was recognized that a substance with anti-oxidative activity is likely to be one that is itself readily oxidized. Research into how vitamin E prevents the process of lipid peroxidation led to the identification of antioxidants as reducing agents that prevent oxidative reactions, often by scavenging reactive oxygen species before they can damage cells.
https://en.wikipedia.org/wiki?curid=3277
358,881
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The launch occurred on November 15, 1990, 18:48:13 EST. It was originally scheduled for July 9, 1990, however, a liquid hydrogen leak found on "Columbia" during the STS-35 countdown prompted three precautionary tanking tests on "Atlantis" at the pad on June 29, 1990, on July 13, and on July 25, 1990. Tests confirmed the hydrogen fuel leak on the external tank side of the external tank/orbiter quick disconnect umbilical. This could not be repaired at the pad and "Atlantis" was rolled back to the VAB on August 9, 1990, demated, then transferred to the Orbiter Processing Facility (OPF). During rollback, the vehicle remained parked outside the VAB for about a day while the "Columbia"/STS-35 stack was transferred to the pad for launch. While outside, "Atlantis" suffered minor hail damage to its tiles during a thunderstorm. After repairs were made in the OPF, "Atlantis" was transferred to the VAB for mating on October 2, 1990. During hoisting operations, the platform beam that was to have been removed from the orbiter's aft compartment fell and caused minor damage, which was repaired. The vehicle rolled out to Pad A on October 12, 1990. The fourth mini-tanking test was performed on October 24, 1990, with no excessive hydrogen or oxygen leakage detected. During the Flight Readiness Review (FRR), the launch date was set for November 9, 1990. The launch was reset for November 15 due to payload problems. Liftoff occurred during a classified launch window lying within a launch period extending from 18:30 to 22:30 EST on November 15, 1990.
https://en.wikipedia.org/wiki?curid=497745
1,343,847
1,876,547
Australia is well known for being one of the driest continents on earth, which is often beset with prolonged droughts, so any opportunity to increase rainfall was seen of great national significance and many innovative and sometimes bizarre ideas were put forward. However, the results from early cloud seeding trials of dropping dry ice from a RAAF Consolidated B24 Liberator on 5 February 1947 in NSW near Sydney were spectacular. It rained for about 3 hours producing over 12 mm uniformly distributed over an area of about 80 square km while surrounding clouds produced no rain. This is believed to be the first documented case anywhere in the world of appreciable man-made rainfall reaching the ground and the first time that dynamic cloud growth had followed seeding.
https://en.wikipedia.org/wiki?curid=57882206
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Over the years, the Arctic ozone layer has depleted severely. As a consequence species that live above the snow cover or in areas where snow has melted abundantly, due to hot temperatures, are negatively impacted due to UV radiation that reaches the ground. Depletion of the ozone layer and allowing excess UVB radiation would initially be assumed to increase damage done to plant DNA. Reports have found that when plants are exposed to UVB radiation similar to stratospheric ozone depletion, there was no significant change in plant height or leaf mass, but showed a response in shoot biomass and leaf area with a small decrease. However, UVB radiation has been shown to decrease quantum yield of photosystem II. UVB damage only occurs under extreme exposure, and most plants also have UVB absorbing flavonoids which allow them to acclimatize to the radiation present. Plants experience different levels of UV radiation throughout the day. It is known that they are able to shift the levels and types of UV sunscreens (i.e. flavonoids), that they contain, throughout the day. This allows them to increase their protection against UV radiation. Plants that have been affected by radiation throughout development are more affected by the inability to intercept light with a larger leaf area than having photosynthetic systems compromised. Damage from UVB radiation is more likely to be significant on species interactions than on plants themselves.
https://en.wikipedia.org/wiki?curid=44183
98,635
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In 1984, expanding on ideas from futurist Ted Nelson, Neil Larson's commercial DOS Maxthink outline program added angle bracket hypertext jumps (adopted by later web browsers) to and from ASCII, batch, and other Maxthink files up to 32 levels deep. In 1986, he released his DOS Houdini knowledge network program that supported 2500 topics cross-connected with 7500 links in each file along with hypertext links among unlimited numbers of external ASCII, batch, and other Houdini files, these capabilities were included in his then popular shareware DOS file browser programs HyperRez (memory resident) and PC Hypertext (which also added jumps to programs, editors, graphic files containing hot spots jumps, and cross-linked thesaurus/glossary files). These programs introduced many to the browser concept and 20 years later, Google still lists 3,000,000 references to PC Hypertext. In 1989, Larson created both HyperBBS and HyperLan which both allow multiple users to create/edit both topics and jumps for information and knowledge annealing which, in concept, the columnist John C. Dvorak says pre-dated Wiki by many years.
https://en.wikipedia.org/wiki?curid=17530988
181,530
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Cartosat-2 carries a state-of-the-art panchromatic (PAN) camera that take black and white pictures of the Earth in the visible region of the electromagnetic spectrum. The swath covered by this high resolution PAN camera is 9.6 km and their spatial resolution is less than 1 metre. The satellite can be steered up to 45° along as well as across the track. Cartosat-2 is an advanced remote sensing satellite capable of providing scene-specific spot imagery. The data from the satellite will be used for detailed mapping and other cartographic applications at cadastral level, urban and rural infrastructure development and management, as well as applications in Land information system (LIS) and Geographic information system (GIS). The first imagery, received on 12 January 2007, covered a length of 240 km from Paonta Sahib in Shivalik region to Delhi. Another set of imagery of about 50 km length covered Radhanagari to Sagoan in Goa. Analysis of the first imagery received at National Remote Sensing Agency's data reception station at Shadnagar, in Hyderabad, confirmed excellent performance of the on-board camera.
https://en.wikipedia.org/wiki?curid=9465973
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This was the 20th appearance of the event, which was not held at the first Olympics in 1896 but has been on the program ever since. Three of the eight finalists from the 1984 Games returned: gold medalist Carl Lewis of the United States, fifth-place finisher Ralf Lübke of West Germany, and seventh-place finisher Pietro Mennea of Italy. Mennea was competing in his fifth Games in this event, having won bronze in 1972, finished fourth in 1976, and won gold in 1980 previously. Lewis was attempting to repeat his 1984 quadruple of winning the 100 metres, 200 metres, long jump, and 4x100 metres relay (and had started well on that goal, winning the 100 and the long jump). He had placed second in the U.S. trials to Joe DeLoach in this event, however, and the competition between the two was expected to be tight. Nobody else running the event was thought to be close to the American pair.
https://en.wikipedia.org/wiki?curid=8144912
1,481,945
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The advantage of previsualization is that it allows a director, cinematographer, production supervisor, or VFX supervisor to experiment with different staging and art direction options—such as lighting, camera placement and movement, stage direction and editing—without having to incur the costs of actual production. On a larger budget project, directors may work with actors in the visual effects department or dedicated rooms. Previsualizations can utilise music, sound effects and dialogue to closely emulate the look of fully produced and edited sequences, and are most encountered in scenes that involve stunts, special effects (such as chroma key), or complex choreography and cinematography. It is also used in works that combine production techniques, such as digital video, photography, and animation, such as 3D animation.
https://en.wikipedia.org/wiki?curid=4668411
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The primary goal of this investigation was to use the results from other experiments, particularly 1981-070A-03, to test theoretical models and to develop new ones, with emphasis on research areas related to auroral arcs, field-aligned currents, plasma wave turbulence associated with anomalous resistance, generation of auroral electron beams, production of kilometric and VLF hiss radiation. In addition, correlation studies were organized by selecting events that were interesting to the various investigators, and data reduction procedures were suggested to facilitate comparison and interpretation of the data.
https://en.wikipedia.org/wiki?curid=69341287
2,135,353
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During the Sicilian revolution of independence of 1848, Cannizzaro served as an artillery officer at Messina and was also chosen deputy for Francavilla in the Sicilian parliament; and, after the fall of Messina in September 1848, he was stationed at Taormina. On the collapse of the insurgents, Cannizzaro escaped to Marseille in May 1849, and, after visiting various French towns, reached Paris in October. There he gained an introduction to Michel Eugène Chevreul's laboratory, and in conjunction with F.S. Cloez (1817–1883) made his first contribution to chemical research, in 1851, when they prepared cyanamide by the action of ammonia on cyanogen chloride in ethereal solution. In the same year, Cannizzaro accepted an appointment at the National College of Alessandria, Piedmont as professor of physical chemistry. In Alessandria, he discovered that aromatic aldehydes are decomposed by an alcoholic solution of potassium hydroxide into a mixture of the corresponding acid and alcohol. For example, benzaldehyde decomposes into benzoic acid and benzyl alcohol, the Cannizzaro reaction.
https://en.wikipedia.org/wiki?curid=940309
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Meanwhile, scientists began recognizing odd magnetic variations across the ocean floor using devices developed during World War II to detect submarines.  Over the next decade, it became increasingly clear that the magnetization patterns were not anomalies, as had been originally supposed. In a series of papers in 1959–1963, Heezen, Dietz, Hess, Mason, Vine, Matthews, and Morley collectively realized that the magnetization of the ocean floor formed extensive, zebra-like patterns: one stripe would exhibit normal polarity and the adjoining stripes reversed polarity.  The best explanation was the "conveyor belt" or Vine–Matthews–Morley hypothesis.  New magma from deep within the Earth rises easily through these weak zones and eventually erupts along the crest of the ridges to create new oceanic crust.  The new crust is magnetized by the earth's magnetic field, which undergoes occasional reversals.  Formation of new crust then displaces the magnetized crust apart, akin to a conveyor belt – hence the name.
https://en.wikipedia.org/wiki?curid=6056
128,633
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Hepatitis C virus (HCV) genotypes refer to the genetic variations that occurs in the hepatitis C virus. Hepatitis C is a contagious disease that primarily affects the liver, causing severe damage as the disease progresses. It is caused by the Hepatitis C virus, a small, enveloped RNA virus. The transmission of hepatitis C is through the contact with the blood of the infected person, for example by sharing the needles or by using non-sterile medical equipment. HCV is transmitted globally because of the high infection rate and is also associated with a high mortality rate. The World Health Organization indicates the 3.3% of the world population is infected by the HCV virus. Statistical records show that there are about 13 million HCV affected persons in Сhina, 3.5 million affected persons in the United States, and about 10 million people are affected by HCV in Pakistan. In all cases, the viral genotype of the HCV stays the same, occasionally mutations do occur making the treatment more complex by targeting the changes in the genotype. Hepatitis C virus genotype is considered more common than the Hepatitis B virus infection contributing to more than a million cases annually and is considered one of the major reason for liver transplantation in United States. Some of the HCV genotypes may develop in people without symptoms leading to dangerous conditions like liver cirrhosis causing a permanent damage to liver and the unnoticed HCV conditions will affect brain, joints, blood vessels, bones, and kidneys.
https://en.wikipedia.org/wiki?curid=52926946
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Top speeds are in practice limited by the longest straight at the track and by the need to balance the car's aerodynamic configuration between high straight-line speed (low aerodynamic drag) and high cornering speed (high downforce) to achieve the fastest lap time. During the 2006 season, the top speeds of Formula 1 cars were a little over 300 km/h (185 mph) at high-downforce tracks such as Albert Park, Australia and Sepang, Malaysia. These speeds were down by some from the 2005 speeds, and from the 2004 speeds, due to the recent performance restrictions (see below). On low-downforce circuits greater top speeds were registered: at Gilles-Villeneuve (Canada) 325 km/h (203 mph), at Indianapolis (USA) 335 km/h (210 mph), and at Monza (Italy) 360 km/h (225 mph). In testing one month prior to the 2005 Italian Grand Prix, Juan Pablo Montoya of the McLaren-Mercedes F1 team recorded a record top speed of 372.6 km/h (231.5 mph), which was officially recognised by the FIA as the fastest speed ever achieved by an F1 car, even though it was not set during an officially sanctioned session during a race weekend. In the 2005 Italian GP Kimi Räikkönen of McLaren-Mercedes was recorded at 370.1 km/h (229.9 mph). This record was broken at the 2016 Mexican Grand Prix by Williams driver Valtteri Bottas, whose top speed in race conditions was 372.54 km/h (231.48 mph). However, even though this information was shown in FIA's official monitors, the FIA is yet to accept it as an official record. Bottas had previously set an even higher record top speed during qualifying for the 2016 European Grand Prix, recording a speed of 378.035 km/h (234.9 mph), albeit through the use of slipstream drafting. This top speed is yet to be confirmed by any official method as currently the only source of this information is the Williams team's Twitter post, while the FIA's official speed trap data measured Bottas's speed at 366.1 km/h in that instance. At the moment Montoya's speed of is still regarded as the official record, even though it was not set during a sanctioned session.
https://en.wikipedia.org/wiki?curid=645083
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Seismographic systems used for petroleum or other mineral exploration historically used an explosive and a wireline of geophones unrolled behind a truck. Now most short-range systems use "thumpers" that hit the ground, and some small commercial systems have such good digital signal processing that a few sledgehammer strikes provide enough signal for short-distance refractive surveys. Exotic cross or two-dimensional arrays of geophones are sometimes used to perform three-dimensional reflective imaging of subsurface features. Basic linear refractive geomapping software (once a black art) is available off-the-shelf, running on laptop computers, using strings as small as three geophones. Some systems now come in an 18" (0.5 m) plastic field case with a computer, display and printer in the cover.
https://en.wikipedia.org/wiki?curid=231826
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Selective 5-HT receptor agonists like the 25-NB compounds, specifically those which can behave as full agonists at this receptor, can cause serotonin syndrome-like adverse effects such as hyperthermia, hyperpyrexia, tachycardia, hypertension, clonus, seizures, agitation, aggression, and hallucinations which has ended in death on numerous occasions despite these particular drugs only being available to drug users for about 2–3 years, being widely in use mostly in the period from 2010-2012. Bans were put in place around 2012-2013 by countries where they had risen to popularity. They quickly and often accidentally lead to overdose. In contrast to the aforementioned drugs's potent, selective, and most importantly, full agonism (meaning the drug can fully activate the receptor to 100% of its activation potential, and does so even with minuscule amounts due to high potency, LSD, like the other "safe" psychedelics which are almost impossible to overdose fatally on, is a partial agonist, and this means it has a limit of how much it can activate the receptor, a limit which is basically impossible to exceed even with exponentially larger amounts of the drug. These partial agonists have proven relatively safe after having seen widespread abuse by drug users for many decades. Activation of the 5-HT receptor is also implicated in serotonin syndrome caused by indirect serotonin receptor agonists like serotonin reuptake inhibitors, serotonin releasing agents, and monoamine oxidase inhibitors. Antagonists of the 5-HT receptor like cyproheptadine and chlorpromazine are able to reverse and mediate recovery from serotonin syndrome.
https://en.wikipedia.org/wiki?curid=7491352
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"Alaunia" was built by John Brown & Company in Scotland to augment the transatlantic passenger fleet of the Cunard Line. The ship entered service in July 1925 and was primarily employed on the Canadian route running from Southampton to Quebec and Montreal during the warm weather months and Halifax during the winter. She was one of a number of so-called intermediate liners built with fuel economy in mind. Designed with a single stack and straight stem bow with four passenger decks, the ship was propelled by two screws powered by four double reduction geared steam turbine engines that gave her a service speed of fifteen knots. Safety features included twelve watertight compartments divided by eleven bulkheads and twenty-eight lifeboats.
https://en.wikipedia.org/wiki?curid=43463282
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In the biogeochemical processes of Earth, sources and sinks are the movement of elements. The composition of salt ions within our oceans and seas is: sodium (Na), chlorine (Cl), sulfate (SO), magnesium (Mg), calcium (Ca) and potassium (K). The elements that comprise salinity do not readily change and are a conservative property of seawater. There are many mechanisms that change salinity from a particulate form to a dissolved form and back. Considering the metallic composition of iron sources across a multifaceted grid of thermomagnetic design, not only would the movement of elements hypothetically help restructure the movement of ions, electrons, and the like, but would also potentially and inexplicably assist in balancing the magnetic bodies of the Earth's geomagnetic field. The known sources of sodium i.e. salts are when weathering, erosion, and dissolution of rocks are transported into rivers and deposited into the oceans.
https://en.wikipedia.org/wiki?curid=248189
117,205
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The Van Allen Building, also known as Van Allen and Company Department Store, is a historic commercial building at Fifth Avenue and South Second Street in Clinton, Iowa. The four-story building was designed by Louis Sullivan and commissioned by John Delbert Van Allen (October 5, 1850 – December 30, 1928). Constructed 1912–1914 as a department store, it now has upper floor apartments with ground floor commercial space. The exterior has brick spandrels and piers over the structural steel skeletal frame. Terra cotta is used for horizontal accent banding and for three slender, vertical applied mullion medallions on the front facade running through three stories, from ornate corbels at the second-floor level to huge outbursts of vivid green terra cotta foliage in the attic. There is a very slight cornice. Black marble facing is used around the glass show windows on the first floor. The walls are made of long thin bricks in a burnt gray color with a tinge of purple. Above the ground floor all the windows are framed by a light gray terra cotta. The tile panels in Dutch blue and white pay tribute to Mr. Van Allen's Dutch heritage of which he was quite proud. (Mr. Van Allen was accepted for membership in the Holland Society of New York in 1908). The Van Allen Building was declared a National Historic Landmark in 1976 for its architecture.
https://en.wikipedia.org/wiki?curid=8899247
1,588,703
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After the M14's adoption, Springfield Armory began tooling a new production line in 1958, delivering the first service rifles to the U.S. Army in July 1959. However, long production delays resulted in the 101st Airborne Division being the only unit in the army fully equipped with the M14 by the end of 1960. The Fleet Marine Force finally completed the change from M1 to M14 in late 1961. Springfield Armory records reflect that M14 manufacture ended as TRW, fulfilling its second contract, delivered its final production increment in fiscal year 1965 (1 July 1964 – 30 June 1965). The Springfield archive also indicates the 1.38 million rifles were acquired for just over $143 million, for a unit cost of about $104.
https://en.wikipedia.org/wiki?curid=319543
37,436
1,537,359
The open book with "" inscribed was later adopted by the then-new New South Wales University of Technology in 1952. The historic constituent colleges, and their surviving constituent unions use their own emblems, with only the City and Guilds's emblem being a coat of arms. Many of the historic medical schools which merged to form Imperial College School of Medicine also had their own coat of arms, although these are no longer used. On 5 June 2020, the college decided to remove the motto from the official rendition of the coat of arms, to address issues of colonialism. This was part of a wider effort to address racial inequality in college provisions following the murder of George Floyd and the ensuing focus on the Black Lives Matter movement. The motto, "", which is translated as ""Scientific knowledge, the crowning glory and the safeguard of the empire"", had always traditionally been shown with the crest, being depicted as such by Fox-Davies as early as 1915. Unusually for an English university motto, it was granted with the coat of arms, which prevented it being updated instead of simply not shown.
https://en.wikipedia.org/wiki?curid=63503807
1,536,488
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Since the CFTR mutation is autosomal recessive, the most significant risk factor is family history. The disease only manifests itself when a child inherits CFTR mutations from both parents. Children who inherit a mutation from one parent are considered carriers and can pass it on to their children. With this being the case, mutations may be family and region specific (See Race, ethnicity, and geographic location). In regard to sex, CF occurs in occurs in males and females; however, women are more likely to display worse symptoms and outcomes. This is particularly relevant in regard to "Peudomonas aeruginosa" respiratory infections. Age-wise, most people are diagnosed by the age of 2; however, the Cystic Fibrosis Foundation Patient Registry shows that more than half of the CF population is age 18 or older in the United States.
https://en.wikipedia.org/wiki?curid=71861413
2,221,544
1,553,429
Viktor Afanaseyev, Musa Manarov (on his second Mir visit), and Toyohiro Akiyama were welcomed aboard Mir by Soviet cosmonauts. Akiyama's network paid for the flight. The Soviets called this their first commercial spaceflight and claimed to have earned $14 million. The journalist was scheduled to make one 10-min TV broadcast and two 20-min radio broadcasts each day. Electrical power and video and TV system incompatibilities forced the Japanese to make extensive use of converters. His equipment, which weighed about 170 kg, was delivered by Progress-M spacecraft and set up in advance by Manakov and Strekalov. On December 5 Akiyama's couch was transferred to Soyuz-TM 10. On December 8 Manakov and Strekalov commenced loading Soyuz-TM 10's descent module with film and experiment results. TBS broadcast Akiyama's landing live from Kazakhstan.
https://en.wikipedia.org/wiki?curid=850898
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"Constellation"s next deployment, from September 1978 to May 1979, was originally scheduled to end in March but was extended due to her sortie into the Indian Ocean in reaction to a political crisis in Yemen. Following a relatively short eight-month turnaround cycle, she was underway again in February 1980 under the command of Captain Leon Edney, USN. After participating in RIMPAC exercises, "Constellation" steamed westward to the Arabian Sea, where Gonzo Station had been established following the November 1979 takeover of the American Embassy in Tehran, Iran. "Connie" had reached the eastern Indian Ocean when the unsuccessful 24 April 1980 raid to free American hostages took place, and she relieved on Gonzo Station on 1 May. This at-sea period would last a record-setting 110 days. As a result, the crew of "Constellation" was awarded the Navy Expeditionary Medal for their service. The deployment ended in mid-October.
https://en.wikipedia.org/wiki?curid=204536
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In radio astronomy, a fast radio burst (FRB) is a transient radio pulse of length ranging from a fraction of a millisecond to 3 seconds, caused by some high-energy astrophysical process not yet understood. Astronomers estimate the average FRB releases as much energy in a millisecond as the Sun puts out in three days. While extremely energetic at their source, the strength of the signal reaching Earth has been described as 1,000 times less than from a mobile phone on the Moon. The first FRB was discovered by Duncan Lorimer and his student David Narkevic in 2007 when they were looking through archival pulsar survey data, and it is therefore commonly referred to as the Lorimer Burst. Many FRBs have since been recorded, including several that have been detected to repeat in seemingly irregular ways. Only one FRB has been detected to repeat in a regular way: FRB 180916 seems to pulse every 16.35 days.
https://en.wikipedia.org/wiki?curid=40408388
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During the 1980s, Coast Guard cutters and aircraft were increasingly deployed to intervene drugs far offshore. While the service has interdicted contraband since its inception, the "Drug War" was the biggest effort since Prohibition. Though the Drug War began before the 1980s and continues to this day, it was during the 1980s that the Coast Guard, working with the Drug Enforcement Administration and other law enforcement agencies, used a blend of new and old laws to interdict far from the shores of the United States. Formerly, it was more difficult to prosecute cases involving seizures made beyond 24 nautical miles from shore. President Ronald Reagan's efforts to secure funding for federal agencies and courts to prosecute cases got the Coast Guard's attention. The Coast Guard instituted a "no tolerance" policy toward drugs, began testing its own employees for drug use, and required that all boardings be carried out by trained and armed boarding officers and petty officers. The Caribbean was the focus of efforts in the 1980s, but in recent years the major drug busts at sea have been occurring more in the waters of the Pacific Ocean between California and Peru.
https://en.wikipedia.org/wiki?curid=6204230
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In July 2017, after Package 1 had been assigned, the nonprofit Citizens Budget Commission released a study critical of the plan. In the study, the CBC noted that the 30 original stations only constituted 8% of weekday boardings, and none of these stations were in the list of 25 most-used stations in 2016. Compared to stations that would only be "renewed" under this Capital Plan, i.e. with less comprehensive improvements performed under partial closures, the average ESI station could be 2 to 2.5 times as expensive as the average non-ESI station. The CBC wrote that the MTA had added $857 million to the ESI's original $64 million in funding, and that the cost of extensive renovations offset the savings afforded by using design–build contracts for ESI projects. The ESI program has also been criticized for the full station closures that entails, which force riders to walk to the next station and add extra time to their commute. Some transit advocates have also pointed out that the Enhanced Station Initiative does not include improvements, such as elevators, that would make the stations compliant with the Americans with Disabilities Act of 1990.
https://en.wikipedia.org/wiki?curid=55208663
1,370,427
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The fruit bodies have caps that are initially convex, before flattening out or becoming slightly depressed, often with a blunt umbo. The cap diameter reaches in diameter. Its dull white surface is covered with brown fibrillose small scales that are most numerous in the center and diminish approaching the cap margin. The cap margin is initially curved inward before straightening out in age. The pale yellow gills are free from attachment to the stem. They are crowded together, and interspersed with 8–9 tiers of lamellulae (short gills). Viewed with a hand lens, the gill edges appear fringed. The stem is roughly cylindrical, often with thicker, somewhat bulbous base. Measuring long by 2–4 mm thick (expanding to up to 6 mm at the base), the stem is hollow, and has a smooth, fibrillose surface. A membranous, whitish ring is located on the upper portion of the stem, but it does not last long before disintegrating. The whitish flesh is up to thick at the center of the cap, and lacks any distinct odor. All parts of the mushroom will stain a greyish-green color if handled.
https://en.wikipedia.org/wiki?curid=37104806
2,043,489
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Hence, unlike previous methods, scale spaces in SURF are implemented by applying box filters of different sizes. Accordingly, the scale space is analyzed by up-scaling the filter size rather than iteratively reducing the image size. The output of the above 9×9 filter is considered as the initial scale layer at scale "s" =1.2 (corresponding to Gaussian derivatives with "σ" = 1.2). The following layers are obtained by filtering the image with gradually bigger masks, taking into account the discrete nature of integral images and the specific filter structure. This results in filters of size 9×9, 15×15, 21×21, 27×27... Non-maximum suppression in a 3×3×3 neighborhood is applied to localize interest points in the image and over scales. The maxima of the determinant of the Hessian matrix are then interpolated in scale and image space with the method proposed by Brown, et al. Scale space interpolation is especially important in this case, as the difference in scale between the first layers of every octave is relatively large.
https://en.wikipedia.org/wiki?curid=12341697
500,816
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EQCM can be used to study the process of adsorption and oxidation of fuel molecules on the electrode surface, and the effect of electrode catalyst or other additives on the electrode, such as assessment of polypyrrole internal Pt load in the polypyrrole/platinum composites fuel cell, methanol fuel cell anodizing process, and electrodeposition of cerium oxide suspended nanoparticles doped with gadolinium oxide under the ultrasound for Co/CeO and Ni/CeO composite fuel cells. EQCM can also be used to study the energy storage performance and influencing factors of supercapacitors and electrochemical capacitors. For example, EQCM is used to study the ion movement gauge of conductive polymer of capacitor on cathode. Some work studied the EQCM application in solar energy, which is mostly additive and thin film material related, for instance, using EQCM to study the electrochemical deposition process and stability of Co-Pi oxygen evolution catalyst for solar storage.
https://en.wikipedia.org/wiki?curid=64536363
1,521,227
1,151,375
All disability types were eligible to participate at the 1992 Summer Paralympics. The IPC oversaw classification based on functional disability. General and functional classification took place in the Paralympic Village, with functional swimming classification taking place on the same dates at the Piscines Bernat Picronell. The process became a contentious issue at the Paralympics because of on-the-spot reclassifications that resulted in changes to the competition schedule. On-the-spot classification or re-classification was viewed as a negative aspect of the 1996 Summer Paralympics, and the Paralympic movement overall. At the 2000 Summer Paralympics, 54 assessments were conducted, resulting in 13 class changes. There was one Paralympic New Status (PNS) protest and two Paralympic Permanent Status (PPS) protests by a national Paralympic committee, with one classification upheld and two denied. Six classification appeals were lodged for swimming at the 2000 Summer Paralympics involving four athletes, resulting in two class changes. For the 2016 Summer Paralympics in Rio de Janeiro, the IPC had a zero classification at the Games policy. This policy was put into place in 2014, with the goal of avoiding last minute changes in classes that would negatively impact athlete training preparations. All competitors needed to be internationally classified with their classification status confirmed prior to the Games, with exceptions to this policy being dealt with on a case-by-case basis. In case there was a need for classification or reclassification at the Games despite best efforts otherwise, swimming classification was scheduled to take place at the Olympic Aquatics Stadium, with visually impaired swimmers getting classified from September 4 to 6 and all other swimmers being classified from September 3 to 5. For sportspeople with physical or intellectual disabilities going through classification or reclassification in Rio de Janeiro, their in-competition observation event is their first appearance in competition at the Games.
https://en.wikipedia.org/wiki?curid=36583541
1,150,768
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All other isotopes of aluminium are radioactive. The most stable of these is Al: while it was present along with stable Al in the interstellar medium from which the Solar System formed, having been produced by stellar nucleosynthesis as well, its half-life is only 717,000 years and therefore a detectable amount has not survived since the formation of the planet. However, minute traces of Al are produced from argon in the atmosphere by spallation caused by cosmic ray protons. The ratio of Al to Be has been used for radiodating of geological processes over 10 to 10 year time scales, in particular transport, deposition, sediment storage, burial times, and erosion. Most meteorite scientists believe that the energy released by the decay of Al was responsible for the melting and differentiation of some asteroids after their formation 4.55 billion years ago.
https://en.wikipedia.org/wiki?curid=904
18,922
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Edward Witten (born August 26, 1951) is an American mathematical and theoretical physicist. He is a Professor Emeritus in the School of Natural Sciences at the Institute for Advanced Study in Princeton. Witten is a researcher in string theory, quantum gravity, supersymmetric quantum field theories, and other areas of mathematical physics. Witten's work has also significantly impacted pure mathematics. In 1990, he became the first physicist to be awarded a Fields Medal by the International Mathematical Union, for his mathematical insights in physics, such as his 1981 proof of the positive energy theorem in general relativity, and his interpretation of the Jones invariants of knots as Feynman integrals. He is considered the practical founder of M-theory.
https://en.wikipedia.org/wiki?curid=54894
276,430
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In the context of a housing shortage and a degree of political instability, May assembled a powerful staff of progressive architects and initiated the large-scale housing development program New Frankfurt. May's developments were remarkable for the time for being compact, semi-independent, well-equipped with community elements like playgrounds, schools, theatres, and common washing areas. For the sake of economy and construction speed May used simplified, prefabricated forms. These settlements are still marked by their functionality and the way they manifest egalitarian ideals such as equal access to sunlight, air, and common areas. Of these settlements the best known is probably Siedlung Römerstadt, and some of the structures are colloquially known as "Zickzackhausen" (zig-zag houses).
https://en.wikipedia.org/wiki?curid=1938475
1,325,771
1,067,914
TFP emphasizes the role of interpretation within psychotherapy sessions. As the split-off representations of self and other get played out in the course of the treatment, the therapist helps the patient to understand the reasons (the fears or the anxieties) that support the continued separation of these fragmented senses of self and other. This understanding is accompanied by the experience of strong affects within the therapeutic relationship. The integration of the split and polarized concepts of self and others leads to a more complex, differentiated, and realistic sense of self and others that allows for better modulation of affects and in turn clearer thinking. Therefore, as split-off representations become integrated, patients tend to experience an increased coherence of identity, relationships that are balanced and constant over time and therefore not at risk of being overwhelmed by aggressive affect, a greater capacity for intimacy, a reduction in self-destructive behaviors, and general improvement in functioning.
https://en.wikipedia.org/wiki?curid=16399962
1,067,360
1,510,989
After five years at the National Bureau of Standards, Huskey joined the faculty of the University of California, Berkeley in 1954 and then University of California, Santa Cruz from 1966. He cofounded the computer and information science program at UC Santa Cruz in 1967. He became director of its computer center. In 1986, UC Santa Cruz named him professor emeritus. While at Berkeley, he supervised the research of pioneering programming language designer Niklaus Wirth, who gained his PhD in 1963. During 1963-1964 Prof. Huskey participated in establishing the Computer Center at IIT Kanpur and convened a meeting there with many pioneers of computing technology. Participants included Forman Acton of Princeton University, Robert Archer of Case Institute of Technology, S. Barton of CDC, Australia, S. Beltran from the Centro de Calculo in Mexico City, John Makepeace Bennett of the University of Sydney, Launor Carter of SDC - author of the subsequent Carter Report on Computer Technology for Schools, David Evans of UC Berkeley, Bruce Gilchrist of IBM-SBC, Clay Perry of UC San Diego, Sigeiti Moriguti of the University of Tokyo, Gio Wiederhold, also of UC Berkeley, Adriaan van Wijngaarden of the Mathematisch Centrum in Amsterdam, Maurice Wilkes of Cambridge University.
https://en.wikipedia.org/wiki?curid=2697684
1,510,139
1,338,460
Vacuum tube equipment used a number of tubes, each with a heater requiring a certain amount of electrical power. In AC/DC equipment, the heaters of all the tubes are connected in series. All the tubes are rated at the same current (typically 100, 150, 300, or 450 mA) but at different voltages, according to their heating power requirements. If necessary, resistance (which can be a ballast tube (barretter), a power resistor or a resistive mains lead are added so that, when the mains voltage is applied across the chain, the specified heating current flows. Some types of ballast resistors were built into an envelope like a tube that was easily replaceable. With mains voltages of around 220 V, the power dissipated by the additional resistance and the voltage drop across it could be quite high, and it was common to use a resistive power cable (mains cord) of defined resistance, running warm, rather than putting a hot resistor inside the case. If a resistive power cable was used, an inexperienced repairer might replace it with a standard cable, or use the wrong length, damaging the equipment and risking a fire.
https://en.wikipedia.org/wiki?curid=19064311
1,337,727
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Natural rewards are associated with a state of deprivation from unmet needs or desires (e.g., hunger). These states drive instinctual, motivated behaviors like food consumption. It has been argued that this is not the case with BSR, as it does not meet an intrinsic survival-based need. BSR also notably lacks an established neural representation in memory that naturally facilitates the learning of reward expectancy. Both of these effects lead to diminished response rate for BSR in the early trials of a series; however, experiments have also shown that extinguished behavior can be quickly reinstated by a priming stimulation that refreshes the short-term association involved in reward expectancy. Studies on BSR indicate that reinforcing brain stimulation may activate the natural pathways associated with natural drives as well as stimulate the reinforcement pathways that are usually activated by natural rewards.
https://en.wikipedia.org/wiki?curid=6226648
1,349,554
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To address these concerns, the American Urological Association established the Shock Wave Lithotripsy Task Force to provide an expert opinion on the safety and risk-benefit ratio of ESWL. The task force published a white paper outlining their conclusions in 2009. They concluded the risk-benefit ratio remains favorable for many people. The advantages of ESWL include its noninvasive nature, the fact that it is technically easy to treat most upper urinary tract calculi, and that, at least acutely, it is a well-tolerated, low-morbidity treatment for the vast majority of people. However, they recommended slowing the shock wave firing rate from 120 pulses per minute to 60 pulses per minute to reduce the risk of renal injury and increase the degree of stone fragmentation.
https://en.wikipedia.org/wiki?curid=38074
137,150
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On 7 December 1941, a group of 12 B-17s of the 38th (four B-17C) and 88th (eight B-17E) Reconnaissance Squadrons, en route to reinforce the Philippines, was flown into Pearl Harbor from Hamilton Field, California, arriving while the surprise attack on Pearl Harbor was going on. Leonard "Smitty" Smith Humiston, co-pilot on First Lieutenant Robert H. Richards' B-17C, AAF S/N "40-2049", reported that he thought the U.S. Navy was giving the flight a 21-gun salute to celebrate the arrival of the bombers, after which he realized that Pearl Harbor was under attack. The Fortress came under fire from Japanese fighter aircraft, though the crew was unharmed with the exception of one member who suffered an abrasion on his hand. Japanese activity forced them to divert from Hickam Field to Bellows Field. On landing, the aircraft overran the runway and ran into a ditch, where it was then strafed. Although initially deemed repairable, "40-2049" (11th BG / 38th RS) received more than 200 bullet holes and never flew again. Ten of the 12 Fortresses survived the attack.
https://en.wikipedia.org/wiki?curid=4997
32,995
741,640
After World War I, the French military sought to replace the 8mm Lebel cartridge, which was poorly suited to large-capacity rifle magazines and to automatic or semi-automatic weapons. After considerable delay, a modern 7.5mm mle 1929 rimless cartridge was finally introduced for the FM 24/29 light machine gun. Berthier rifles were converted ("Fusil Mle 1907/15-M34") or newly manufactured ("Fusil Mle 1934") to make use of the new round. However, this was merely an interim measure, as the French Army adopted the MAS-36 as its new standard bolt-action rifle. In the end, the production of converted Mle 1907/15-M34 Berthier rifles was limited to approximately 80,000 units.
https://en.wikipedia.org/wiki?curid=12812847
741,248
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The Merlin HM2 ("Grey Merlin") is the FAA's primary anti-submarine warfare (ASW) helicopter, having replaced the Sea King HAS6 in the role. It is presently deployed with various ships of the Royal Navy. Merlin HM2 is set to operate Crowsnest replace the recently retired ASaC7 variant of the Sea King, which operated in the AEW role. The first Merlin HM2 test flight with Crowsnest was completed in April 2019. Initial operating capability of the system was significantly delayed. While Crowsnest was deployed with the U.K. carrier strike group in 2021, it experienced operating challenges and revised plans will now see Crowsnest achieve initial operating capability in the second quarter of 2023 and full operating capability in 2024/25. While all Merlins in the Royal Navy will be equipped to operate Crowsnest, only ten kits for the system are being acquired. It has been reported that initially five Merlins will be equipped with Crowsnest, three of these being normally assigned to the "high readiness" aircraft carrier.
https://en.wikipedia.org/wiki?curid=51777
320,457
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In 2005, sales went beyond 200,000 Hybrids, but in retrospect that only reduced the global use for gasoline consumption by 200,000 gallons per day—a tiny fraction of the 360 million gallons used per day. According to Bradley Berman author of "Driving Change—One Hybrid at a time", "cold economics shows that in real dollars, except for a brief spike in the 1970s, gas prices have remained remarkably steady and cheap. Fuel continues to represent a small part of the overall cost of owning and operating a personal vehicle". Other marketing tactics include greenwashing which is the "unjustified appropriation of environmental virtue."
https://en.wikipedia.org/wiki?curid=157736
129,184
1,974,392
Since 1958, SHP has offered courses spanning the full range of the pure and applied sciences, from organic chemistry, neuroscience and physiological psychology, to computer programming in Java and calculus in the complex plane, as well as introductions to special relativity, quantum theory, particle physics and physical cosmology. The program was directed by educator Donald Barr from its inception until 1964, and during that period admitted students as young as ten years old. It boasts many famous alumni, including the creator of GNU, Richard Stallman, and several Nobel Laureates. The program was run by Professor Allan Blaer for many years, and has recently been taken over by Professor Jeremy Dodd.
https://en.wikipedia.org/wiki?curid=13080068
1,973,257
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Lodestones have frequently been displayed as valuable or prestigious objects. The Ashmolean Museum in Oxford contains a lodestone adorned with a gilt coronet that was donated by Mary Cavendish in 1756, possibly to secure her husband's appointment as Chancellor of Oxford University. Isaac Newton's signet ring reportedly contained a lodestone which was capable of lifting more than 200 times its own weight. And in 17th century London, the Royal Society displayed a six-inch spherical lodestone (a "terrella" or 'little Earth'), which was used to illustrate the Earth's magnetic fields and the function of mariners' compasses. One contemporary writer, the satirist Ned Ward, noted how the "terrella" "made a paper of Steel Filings prick up themselves one upon the back of another, that they stood pointing like the Bristles of a "Hedge-Hog"; and gave such Life and Merriment to a Parcel of Needles, that they danc'd [...] as if the devil were in them."
https://en.wikipedia.org/wiki?curid=211177
278,059
1,217,581
Jones has published several papers suggesting that the World Trade Center was demolished with explosives, but his 2005 paper, "Why Indeed Did the WTC Buildings Collapse?" was his first paper on the topic and was considered controversial both for its content and its claims to scientific rigor. Jones' early critics included members of BYU's engineering faculty; shortly after he made his views public, the BYU College of Physical and Mathematical Sciences and the faculty of structural engineering issued statements in which they distanced themselves from Jones' work. They noted that Jones' "hypotheses and interpretations of evidence were being questioned by scholars and practitioners," and expressed doubts on whether they had been "submitted to relevant scientific venues that would ensure rigorous technical peer review." Jones further presented and defended his research before peers at the Utah Academy of Sciences, Arts and Letters on 7 April 2006 at nearby Snow College.
https://en.wikipedia.org/wiki?curid=3171735
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As well as enabling data exchange, CCPN aims to develop software for processing, analysis and interpretation of macromolecular NMR data. To this end CCPN has created CcpNmr Analysis; a graphical program for spectrum visualisation, assignment and NMR data analysis. Here, the requirement was for a program that used a modern graphical user interface and could run on many types of computer. It would be supported and maintained by CCPN and would allow modification and extension, including for new NMR techniques. The first version of Analysis was released in 2005 and is now at version 2.1. Analysis is built directly on the CCPN data model and its design is partly inspired by the older ANSIG. and SPARKY programs, but it has continued to develop from the suggestions, requirements and computational contributions of its user community. Analysis is freely available to academic and non-profit institutions. Commercial users are required to subscribe to CCPN for a moderate fee. CCPN software, including Analysis, is available for download at the CCPN web site and is supported by an active JISC email discussion group.
https://en.wikipedia.org/wiki?curid=24686241
2,212,507
62,633
While there are multiple mentions of "natural body cycle" in Eastern and Native American cultures, the earliest recorded Western account of a circadian process is credited to Theophrastus, dating from the 4th century BC, probably provided to him by report of Androsthenes, a ship's captain serving under Alexander the Great. In his book, 'Περὶ φυτῶν ἱστορία', or 'Enquiry into plants', Theophrastus describes a "tree with many leaves like the rose, and that this closes at night, but opens at sunrise, and by noon is completely unfolded; and at evening again it closes by degrees and remains shut at night, and the natives say that it goes to sleep." The tree mentioned by him was much later identified as the tamarind tree by the botanist, H Bretzl, in his book on the botanical findings of the Alexandrian campaigns.
https://en.wikipedia.org/wiki?curid=56565
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Michael W. Deem is an American engineer, scientist, inventor, and entrepreneur. Deem received his B.S. in Chemical Engineering from the California Institute of Technology in 1991 and his Ph.D. in Chemical Engineering from the University of California at Berkeley in 1994. His thesis research was in statistical mechanics and disordered materials with David Chandler. He did postdoctoral research at Harvard University in Physics with David R. Nelson. Deem joined the faculty at University of California, Los Angeles, in 1996 and rose to the rank of Associate Professor of Chemical Engineering. From 2002 to 2020 Deem was the John W. Cox Professor of Biochemical and Genetic Engineering and Professor of Physics & Astronomy at Rice University in Houston, Texas. Deem was the founding director of the Graduate Program in Systems, Synthetic, and Physical Biology at Rice University, 2012-2014. From 2014 to 2017, Deem served as the Chair of the Bioengineering Department at Rice University.
https://en.wikipedia.org/wiki?curid=24579360
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In 1996, a Russian continuity of government facility, Kosvinsky Mountain, which is believed to be a counterpart to the US Cheyenne Mountain Complex, was completed. It was designed to resist US earth-penetrating nuclear warheads, and is believed to host the Russian Strategic Rocket Forces alternate command post, a post for the general staff built to compensate for the vulnerability of older Soviet era command posts in the Moscow region. In spite of this, the primary command posts for the Strategic Rocket Forces remains Kuntsevo in Moscow and the secondary is the Kosvinsky Mountain in the Ural Mountains. The timing of the Kosvinsky facilities completion date is regarded as one explanation for U.S. interest in a new nuclear "bunker buster" Earth-penetrating warhead and the declaration of the deployment of the B-61 mod 11 in 1997; Kosvinsky is protected by about 1000 feet of granite.
https://en.wikipedia.org/wiki?curid=36880
93,851
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While there is little debate that rhBMPs are successful clinically, there is controversy about their use. It is common for orthopedic surgeons to be paid for their contribution to the development of a new product, but some of the surgeons responsible for the original Medtronic-supported studies on the efficacy of rhBMP-2 have been accused of bias and conflict of interest. For example, one surgeon, a lead author on four of these research papers, did not disclose any financial ties while with the company on three of the papers; he was paid over $4 million by Medtronic. In another study, the lead author did not disclose any financial ties to Medtronic; he was paid at least $11 million by the company. In a series of 12 publications, the median financial ties of the authors to Medtronic were $12–16 million. In those studies that had more than 20 and 100 patients, one or more authors had financial ties of $1 million and $10 million, respectively. Early clinical trials using rhBMP-2 underreported adverse events associated with treatment. In the 13 original industry-sponsored publications related to safety, there were zero adverse events in 780 patients. It has since been revealed that potential complications can arise from the use including implant displacement, subsidence, infection, urogenital events, and retrograde ejaculation.
https://en.wikipedia.org/wiki?curid=1876572
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The techniques in tracking the spacecraft and geophysical interpretation of surface features can affect the resolution of the strength of gravity field. The better technique favors spherical harmonic solutions to higher degrees and orders. Independent analysis on Mariner 9 and Viking Orbiter tracking data yielded a degree and order of 6 spherical harmonic solution., Further combination of the two data sets, along with correlation of anomalies with volcanic features (positive anomaly) and deep-printed depression (negative anomaly) assisted by image data allows a degree and order of 18 spherical harmonic solution produced. Further use of spatial a priori constraint method, which had taken the topography into account in solving the Kaula power law constraint, had favored model of up to degree 50 spherical harmonic solution in global resolution (Goddard Mars Model-1, or GMM-1) then the subsequent models with higher completeness and degree and order up to 120 for the latest GMM-3.
https://en.wikipedia.org/wiki?curid=55521195
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The design and fabrication process of this particular microfluidic device entails first covering the edges of a glass surface with tape (or any protective film) such as to contour the substrate's desired shape. A spin coat layer of PNIPA is then applied. After its dissolution, the protective film is peeled away, resulting in a self-standing body of PNIPA. The final steps involve the spin coating of protective surface of PDMS over the cover slip and curing. Muscular thin films (MTF) enable cardiac muscle monolayers to be engineered on a thin flexible substrate of PDMS. In order to properly seed the 2D cell culture, a microcontact printing technique was used to lay out a fibronectin "brick wall" pattern on the PDMS surface. Once the ventricular myocytes were seeded on the functionalized substrate, the fibronectin pattern oriented them to generate an anisotropic monolayer.
https://en.wikipedia.org/wiki?curid=33980770
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Most weather forecasting is done on the basis of interpreting numerical model results. Since forecasts are typically a few days or a week and sea surface temperatures change relatively slowly, such models do not usually contain an ocean model but rely on imposed SSTs. They also require accurate initial conditions to begin the forecast typically these are taken from the output of a previous forecast, blended with observations. Weather predictions are required at higher temporal resolutions than climate projections, often sub-hourly compared to monthly or yearly averages for climate. However, because weather forecasts only cover around 10 days the models can also be run at higher vertical and horizontal resolutions than climate mode. Currently the ECMWF runs at resolution as opposed to the scale used by typical climate model runs. Often local models are run using global model results for boundary conditions, to achieve higher local resolution: for example, the Met Office runs a mesoscale model with an resolution covering the UK, and various agencies in the US employ models such as the NGM and NAM models. Like most global numerical weather prediction models such as the GFS, global climate models are often spectral models instead of grid models. Spectral models are often used for global models because some computations in modeling can be performed faster, thus reducing run times.
https://en.wikipedia.org/wiki?curid=164600
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Forecasters say they are less skilful at predicting the intensity of tropical cyclones than cyclone track. Available computing power limits forecasters' ability to accurately model a large number of complex factors, such as exact topology and atmospheric conditions, though with increased experience and understanding, even models with the same resolution can be tuned to more accurately reflect real-world behaviour. Another weakness is lack of frequent wind speed measurements in the eye of the storm. The Cyclone Global Navigation Satellite System, launched by NASA in 2016, is expected to provide much more data compared to sporadic measurements by weather buoys and hurricane-penetrating aircraft.
https://en.wikipedia.org/wiki?curid=10575816
1,767,266
535,334
In 2005, GE Hitachi filed design certification by NRC for their Economic Simplified Boiling Water Reactor (ESBWR). The ESBWR received a positive Safety Evaluation Report and Final Design Approval on March 9, 2011. On June 7, 2011, the NRC completed its public comment period. Final rule was issued on September 16, 2014, after two outstanding problems with GE-Hitachi's modeling of loads on the steam dryer were solved. In 2013, following its purchase of Horizon Nuclear Power, Hitachi began the process of generic design assessment of the Hitachi-GE ABWR with the UK Office for Nuclear Regulation. The process was completed in December 2017. In January 2020, the company started the regulatory licensing process for the BWRX-300 with the U.S. Nuclear Regulatory Commission.
https://en.wikipedia.org/wiki?curid=30930902
535,055
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Six high school players committed to play for BYU from the 2020 recruiting class. Richie Saunders, Dallin Hall, Tanner Hayhurst and Tanner Toolson each plan to complete two-year full-time missionary service before joining the team for the 2022–23 season. Only Townsend Tripple and Caleb Lohner will join the roster for the 2020–21 season. Tripple had originally planned to complete missionary service before joining the team and was assigned to Argentina, but decided to delay his mission trip due to coronavirus and joined the roster as a walk-on. In early June, it was reported that Caleb Lohner, a four-star forward from Texas who had previously signed with Utah, requested a release from his National Letter of Intent to sign with BYU. Lohner was released, and on June 26 officially signed with the Cougars. Lohner will be a true freshman and is immediately eligible to play.
https://en.wikipedia.org/wiki?curid=62232280
1,879,903
1,873,014
In 1997, with the renovation of Van Rensselaer Hall, Drexel University began a period of expansion led by president Constantine Papadakis to enlarge the university, its student population, and its alumni funding base. Since 1997, Drexel has completed four new dormitories with plans for at least one more, expanded the research infrastructure with the construction of the Bossone Research Center, renovated various campus buildings and the main quad, and acquired the Queen Lane campus and Hahnemann University Hospital from MCP Hahnemann University. Papadakis has also added a School of Law and secured millions of dollars worth of alumni grants, including several grants of more than $10 million. From 1996 to 2005 total revenue increased +331% to $612M, research funds increased +535% to $83M, the endowment increased +471% to $540M, and total enrollment increased +102% to 18,466. During this time, undergraduate tuition increased +68% to $23,250/year.
https://en.wikipedia.org/wiki?curid=7621515
1,871,937
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It was only towards the end of the 18th century that detailed triangulation network surveys mapped whole countries. In 1784, a team from General William Roy's Ordnance Survey of Great Britain began the Principal Triangulation of Britain. The first Ramsden theodolite was built for this survey. The survey was finally completed in 1853. The Great Trigonometric Survey of India began in 1801. The Indian survey had an enormous scientific impact. It was responsible for one of the first accurate measurements of a section of an arc of longitude, and for measurements of the geodesic anomaly. It named and mapped Mount Everest and the other Himalayan peaks. Surveying became a professional occupation in high demand at the turn of the 19th century with the onset of the Industrial Revolution. The profession developed more accurate instruments to aid its work. Industrial infrastructure projects used surveyors to lay out canals, roads and rail.
https://en.wikipedia.org/wiki?curid=60891
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In 1971, American paleontologist Peter Vaughn described one of the few dissorophids outside of New Mexico, Texas, and Oklahoma, "Astreptorhachis ohioensis" from the late Carboniferous of Ohio, represented by a series of fused neural spines and osteoderms. American paleontologist John Bolt published a survey of dissorophid osteoderms in 1974 with an emphasis on taxonomic utility and differentiation and reports of material from the early Permian Richards Spur locality in Oklahoma; in 1977, Bolt reported "Cacops" from the locality. In 1980, Russian paleontologist Yuri Gubin described two new middle Permian dissorophids from Russia: "Iratusaurus vorax" and "Kamacops acervalis". The most complete cranial material of "Platyhystrix rugosus" was described in 1981 by a team led by American paleontologist David Berman. Additional postcranial material of "Platyhystrix", primarily the characteristic hyperelongate spines, was also periodically reported. The revision of "Ecolsonia cutlerensis" in 1985 by Berman and colleagues placed the taxon as a dissorophid, but this taxon is more often recovered as a trematopid. In 1999, Chinese paleontologists Li Jinling and Cheng Zhengwu described the first and only dissorophid from eastern Asia, the middle Permian "Anakamacops petrolicus" from China.
https://en.wikipedia.org/wiki?curid=2917704
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The Fire Support and Target Acquisition Division directed efforts to improve the quality and quantity of artillery fire support while also simplifying the tasks necessary to provide this artillery fire support. Researchers often utilized commercially available test bed technologies to evaluate solutions to soldier and machine interface problems. The Test Bed Development team created new systems to evaluate concepts intended to reduce crew size and training requirements as well as increase survivability and firing platform responsiveness. The Combined Arms Command and Control team investigated new methods to simplify the planning of supporting artillery fires and enhance their responsiveness by improving the command and control interface. The Studies and Concepts team devised new fire support systems concepts, which enabled the team to define fire support system errors and develop a novel Global Positioning System artillery fuze concept.
https://en.wikipedia.org/wiki?curid=70607475
2,080,788
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There are critical periods in infancy and childhood during which development of certain perceptual, sensorimotor, social and language systems depends crucially on environmental stimulation. Feral children such as Genie, deprived of adequate stimulation, fail to acquire important skills and are unable to learn in later childhood. In this case, Genie is used to represent the case of a feral child because she was socially neglected and abused while she was just a young girl. She underwent abnormal child psychology which involved problems with her linguistics. This happened because she was neglected while she was very young with no one to care about her and had less human contact. The concept of critical periods is also well-established in neurophysiology, from the work of Hubel and Wiesel among others. Neurophysiology in infants generally provides correlating details that exists between neurophysiological details and clinical features and also focuses on vital information on rare and common neurological disorders that affect infants.
https://en.wikipedia.org/wiki?curid=9014
374,584
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In biochemistry, a hypothetical protein is a protein whose existence has been predicted, but for which there is a lack of experimental evidence that it is expressed in vivo. Sequencing of several genomes has resulted in numerous predicted open reading frames to which functions cannot be readily assigned. These proteins, either orphan or conserved hypothetical proteins, make up ~ 20% to 40% of proteins encoded in each newly sequenced genome. The real evidences for the hypothetical protein functioning in the metabolism of the organism can be predicted by comparing its sequence or structure homology by considering the conserved domain analysis. Even when there is enough evidence that the product of the gene is expressed, by techniques such as microarray and mass-spectrometry, it is difficult to assign a function to it given its lack of identity to protein sequences with annotated biochemical function. Nowadays, most protein sequences are inferred from computational analysis of genomic DNA sequence. Hypothetical proteins are created by gene prediction software during genome analysis. When the bioinformatic tool used for the gene identification finds a large open reading frame without a characterised homologue in the protein database, it returns "hypothetical protein" as an annotation remark.
https://en.wikipedia.org/wiki?curid=4635854
1,738,100
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Some microorganisms have a version of 5-"enol"pyruvylshikimate-3-phosphate synthase (EPSPS: EC 2.5.1.19, 3-phosphoshikimate 1-carboxyvinyltransferase; 5-"enol"pyruvylshikimate-3-phosphate synthetase; phospho"enol"pyruvate:3-phosphoshikimate 5-"O"-(1-carboxyvinyl)-transferase) that is resistant to glyphosate inhibition. The version used in genetically modified crops was isolated from "Agrobacterium" strain CP4 (CP4 EPSPS) that was resistant to glyphosate. The CP4 EPSPS gene was cloned and inserted into soybeans. The CP4 EPSPS gene was engineered for plant expression by fusing the 5' end of the gene to a chloroplast transit peptide derived from the petunia EPSPS. This transit peptide was used because it had shown previously an ability to deliver bacterial EPSPS to the chloroplasts of other plants. The plasmid used to move the gene into soybeans was PV-GMGTO4. It contained three bacterial genes, two CP4 EPSPS genes, and a gene encoding beta-glucuronidase (GUS) from "Escherichia coli" as a marker. The DNA was injected into the soybeans using the particle-acceleration method or "gene gun". Soybean cultivar A54O3 was used for the transformation. The expression of the GUS gene was used as the initial evidence of transformation. GUS expression was detected by a staining method in which the GUS enzyme converts a substrate into a blue precipitate. Those plants that showed GUS expression were then taken and sprayed with glyphosate and their tolerance was tested over many generations.
https://en.wikipedia.org/wiki?curid=14606635
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No definitive antidote for amatoxin poisoning is available, but some specific treatments such as intravenous penicillin G have been shown to improve survival. There is some evidence that intravenous silibinin, an extract from the blessed milk thistle ("Silybum marianum"), may be beneficial in reducing the effects of amatoxins, preventing their uptake by hepatocytes, thereby protecting undamaged hepatic tissue. In patients developing liver failure, a liver transplant is often the only option to prevent death. Liver transplants have become a well-established option in amatoxin poisoning. This is a complicated issue, however, as transplants themselves may have significant complications and mortality; patients require long-term immunosuppression to maintain the transplant. Evidence suggests that, although survival rates have improved with modern medical treatment, in patients with moderate to severe poisoning up to half of those who did recover suffered permanent liver damage. However, a follow-up study has shown that most survivors recover completely without any sequelae if treated within 36 hours of mushroom ingestion.
https://en.wikipedia.org/wiki?curid=9315206
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The symptoms of the disease include a high fever with frontal headaches, chills, severe muscle pain, vomiting, and other gastrointestinal symptoms. Bleeding problems may occur 3–4 days after initial symptom onset. Patients may experience abnormally low blood pressure, and low platelet, red blood cell, and white blood cell count. After 1–2 weeks of symptoms, some patients recover without complication. However, the illness is biphasic for a subset of patients (10-20%) who experience a second wave of symptoms at the beginning of the third week. These symptoms include fever and signs of neurological manifestations, such as severe headache, mental disturbances, tremors, and vision deficits. The convalescent period is typically very long, lasting several months. Muscle aches and weakness also occur during this period, and the patient is unable to engage in physical activities.
https://en.wikipedia.org/wiki?curid=1929452
1,076,352
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LIM domains are protein structural domains, composed of two contiguous zinc fingers, separated by a two-amino acid residue hydrophobic linker. The domain name is an acronym of the three genes in which it was first identified (LIN-11, Isl-1 and MEC-3). LIM is a protein interaction domain that is involved in binding to many structurally and functionally diverse partners. The LIM domain appeared in eukaryotes sometime prior to the most recent common ancestor of plants, fungi, amoeba and animals. In animal cells, LIM domain-containing proteins often shuttle between the cell nucleus where they can regulate gene expression, and the cytoplasm where they are usually associated with actin cytoskeletal structures involved in connecting cells together and to the surrounding matrix, such as stress fibers, focal adhesions and adherens junctions.
https://en.wikipedia.org/wiki?curid=9053177
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Results in embryology had been contradictory: in 1888 Wilhelm Roux, who had introduced the experimental manipulation of the embryo to discover the rules of development, performed a series of experiments in which he inserted a hot needle into one of two blastomeres to kill it. He then observed how the remaining blastomere developed, and found that it became a half embryo. In 1892 Hans Driesch performed similar experiments on sea urchin embryos, but instead of killing one of the two blastomeres he put many embryos in a tube and shook it to separate the cells. He reported that, contrary to Roux's findings, he ended up with completely formed but smaller embryos. The reason for this discrepancy has been widely attributed to Driesch separating the two blastomeres completely rather than just killing one as Roux had done. Others, including Thomas Hunt Morgan and Oscar Hertwig, attempted to separate the two cells, for the matter was of great importance, particularly to the arguments between proponents of epigenesis and preformation, but satisfactory results could not be achieved.
https://en.wikipedia.org/wiki?curid=316141
1,123,521
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In the late 19th century the "corpus" phrase began to appear in the notes of the German historians of philosophy, such as Zeller and Windelband. By implication they meant Bekker, but even as they wrote a new manuscript was being excavated from the trash-heaps of Egypt about which Bekker knew nothing at all, or anyone else for at least a few thousand years: the Constitution of the Athenians (Aristotle). It was identified as being one of 158 political studies written by Aristotle and his students no earlier than 330 BC. It is in the "notebook" format. The content differs in that it is not an abstract treatise but is a history stating periods and dates. Not being able to fit it into an idea of the "corpus" based on Bekker, many rejected it. The date being quite ancient, the majority view is to accept it as of Alexandrian provenience, the only instance of an Aristotelicum from the library and school there.
https://en.wikipedia.org/wiki?curid=1666053
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The US opening of Battle of Anzio the next day immediately stripped "Luftflotte" 3 of 100 of their bombers, which were sent to Italy. "Steinbock" attacks continued through February with similarly bad results; by the end of the month the Mosquitoes had claimed 28 aircraft. Large attacks continued sporadically through March, including the night of 19/20 March when Joe Singleton and Geoff Haslam of No. 25 Sqn shot down three Ju 88's in a 13-minute span. Such events were not uncommon, and a number of crews racked up multi-kill missions. Smaller raids continued through the end of April with some harassment raids in May, by which point "Luftflotte" 3's force had fallen from 695 to just 133 operational aircraft. In comparison, RAF losses were about two dozen, with only one of those to enemy action.
https://en.wikipedia.org/wiki?curid=43764346
1,560,364
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"Developmental prosopagnosia" (DP), also called "congenital prosopagnosia" (CP), is a face-recognition deficit that is lifelong, manifesting in early childhood, and that cannot be attributed to acquired brain damage. While developmental prosopagnosia begins early in life, many people do not realize that they have DP until later in their adult lives. A number of studies have found functional deficits in DP both on the basis of EEG measures and fMRI. It has been suggested that a genetic factor is responsible for the condition. The term "hereditary prosopagnosia" was introduced if DP affected more than one family member, essentially accenting the possible genetic contribution of this condition. To examine this possible genetic factor, 689 randomly selected students were administered a survey in which seventeen developmental prosopagnosics were quantifiably identified. Family members of fourteen of the DP individuals were interviewed to determine prosopagnosia-like characteristics, and in all fourteen families, at least one other affected family member was found.
https://en.wikipedia.org/wiki?curid=486429
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Cataclasis, or comminution, is a non-elastic brittle mechanism that operates under low to moderate homologous temperatures, low confining pressure and relatively high strain rates. It occurs only above a certain differential stress level, which is dependent on fluid pressure and temperature. Cataclasis accommodates the fracture and crushing of grains, causing grain size reduction, along with frictional sliding on grain boundaries and rigid body grain rotation. Intense cataclasis occurs in thin zones along slip or fault surfaces where extreme grain size reduction occurs. In rocks, cataclasis forms a cohesive and fine-grained fault rock called cataclasite. Cataclastic flow occurs during shearing when a rock deform by microfracturing and frictional sliding where tiny fractures (microcracks), and associated rock fragments move past each other. Cataclastic flow usually occurs at diagenetic to low-grade metamorphic conditions. However, this depends on the mineralogy of the material and the extent of pore fluid pressure. Cataclastic flow is generally unstable and will terminate by the localization of deformation into slip on fault planes.
https://en.wikipedia.org/wiki?curid=14259252
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More recently, there has been a focus on highly parallel implementations based on garbled circuits, designed to be run on CPUs with many cores. Kreuter, et al. describe an implementation running on 512 cores of a powerful cluster computer. Using these resources they could evaluate the 4095-bit edit distance function, whose circuit comprises almost 6 billion gates. To accomplish this they developed a custom, better optimized circuit compiler than Fairplay and several new optimizations such as pipelining, whereby transmission of the garbled circuit across the network begins while the rest of the circuit is still being generated. The time to compute AES was reduced to 1.4 seconds per block in the active case, using a 512-node cluster machine, and 115 seconds using one node. Shelat and Shen improve this, using commodity hardware, to 0.52 seconds per block. The same paper reports on a throughput of 21 blocks per second, but with a latency of 48 seconds per block.
https://en.wikipedia.org/wiki?curid=646233
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In current prosthetic applications, the C-Leg system developed by Otto Bock HealthCare, is used to replace a human leg that has been amputated because of injury or illness. The use of sensors in the artificial C-Leg aids in walking significantly by attempting to replicate the user's natural gait, as it would be prior to amputation. A similar system is being developed by the Swedish orthopedic company Integrum, the OPRA Implant System, which is surgically anchored and integrated by means of osseointegration into the skeleton of the remainder of the amputated limb. The same company has developed e-OPRA, a will-powered upper limb prosthesis system that is being evaluated in a clinical trial to allow sensory input to the central nervous system using pressure and temperature sensors in the prosthesis' finger tips. Prostheses like the C-Leg, the e-OPRA Implant System, and the iLimb, are considered by some to be the first real steps towards the next generation of real-world cyborg applications. Additionally cochlear implants and magnetic implants which provide people with a sense that they would not otherwise have had can additionally be thought of as creating cyborgs..
https://en.wikipedia.org/wiki?curid=20756967
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These interneurons are connected to one another via synapses and a minority, approximately 15% of the neurons, exhibit bidirectional capacity and were excitatory. About 77% of these neurons indicated a one-way mode of transmitting signals which were inhibitory in nature. These numbers were modeled from an arthropod as pre-motor elements in the motor control system. They were located in the abdominal region. Synapses are known as gaps between neurons which facilitate the spread of a message via neurotransmitters that may excite or depress the subsequent neuron through a complex cascade of electrochemical events. For the interneurons exhibiting one-way signaling, they would receive an excitatory stimulus, experimentally, and the post-synaptic cell was given an inhibitory signal. The interaction between the two cells was modulatory in which the pre-synaptic cell with the initial excitatory signal would mediate the postsynaptic cell even after being inhibited. Signal amplitude was used to determine the effects of the modulation on the signal transmission.
https://en.wikipedia.org/wiki?curid=33244792
1,635,154
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Carus asked Anning to write her name and address in his pocketbook for future reference—she wrote it as "Mary Annins"—and when she handed it back to him she told him: "I am well known throughout the whole of Europe". As time passed, Anning's confidence in her knowledge grew, and in 1839 she wrote to the "Magazine of Natural History" to question the claim made in an article, that a recently discovered fossil of the prehistoric shark "Hybodus" represented a new genus, as an error since she had discovered the existence of fossil sharks with both straight and hooked teeth many years ago. The extract from the letter that the magazine printed was the only writing of Anning's published in the scientific literature during her lifetime. Some personal letters written by Anning, such as her correspondence with Frances Augusta Bell, were published while she was alive, however.
https://en.wikipedia.org/wiki?curid=38334
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The output of the United States also underwent a similar change. The US is ranked the 10th largest shipbuilder worldwide. The top companies that build large naval vessels, such as aircraft carriers and frigates, include Huntington Ingalls, Bollinger and General Dynamics. In the small to medium military vessels category, key shipbuilders include Vigor Industrial, and VT Halter Marine. As the US Navy is shifting to a new fleet architecture that is more widely distributed, Unmanned Surface Vehicles (USVs) development is rapidly propelled to higher priority. Key strategic Program of Record includes prototyping and construction of up to 9 MUSVs, for which a sole contract was awarded to L3Harris Technologies, who partnered with Swiftships to build the MUSVs.
https://en.wikipedia.org/wiki?curid=187377
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Other instruments include a swivel chair for vestibular function tests, lower body negative pressure gear for cardiovascular studies, bicycle ergometer integrated physical trainer (electrically driven running track 1 m X .3 m with elastic cords providing 50 kg load), penguin suits and alternate athletic suit, sensors for temperature and characteristics of upper atmosphere, ITS-K infrared telescope spectrometer and ultraviolet spectrometer for study of earth's infrared radiation, multispectral earth resources camera, cosmic ray detector, embryological studies, new engineering instruments tested for orientation of station by celestial objects and in darkness and a teletypewriter.
https://en.wikipedia.org/wiki?curid=245798
1,266,751
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When the SPSE mechanism explaining MRLS was identified, it was immediately apparent that the model might be an ancient defensive mechanism of caterpillars, and that MRLS-like syndromes might well exist and be identified elsewhere. In 2004, Dr. Thomas Tobin was contacted by a horse farmer in NSW, Australia, who was faced with what she believed were caterpillar-related abortions on her farm in eastern Australia. She put Tobin in touch with the investigating veterinarian, Dr. Nigel Perkins, who at that time understood the Kentucky MRLS outbreak to be black cherry tree/cyanide-driven. Advice to Perkins was brief and unequivocal—given the similarities between MRLS and the syndrome he was describing and the possible role of caterpillars in his syndrome, his experimental approaches should be to first test the caterpillars, any and all other abortigenic candidates, test second. Following this advice, the recommended caterpillar administration experiments were performed and the local processionary caterpillar was identified as the cause of the Australian caterpillar-driven abortion syndrome, which was named "Equine Amnionitis and Fetal Loss".
https://en.wikipedia.org/wiki?curid=4016448
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Early use of acoustic releases for oceanography are reported in the 1960s, when it was recognized that deep ocean currents could more accurately be measured with sea floor mounted rather than ship board instruments. An obvious means of recovery was the use of a surface marker buoy linked to the sea floor instrument, but in areas of high ship traffic or the presence of ice bergs, this proved problematic. The acoustic release became a method to solve that problem, allowing the current meters to remain unattended on the seafloor for weeks or more, until the research vessel returned and triggered the release of the instrument by remote command, allowing it to float to the surface. In the book "Descriptive Physical Oceanography", authors Pickard and Emery vividly describe the recovery phase:
https://en.wikipedia.org/wiki?curid=21771476
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The four-year, full-time undergraduate program maintains a balance between professional majors and those in the arts and sciences. In 2010, it was dubbed "most selective" by "U.S. News", admitting few transfer students and 4.1% of its applicants in the 2020–2021 admissions cycle. MIT offers 44 undergraduate degrees across its five schools. In the 2017–2018 academic year, 1,045 Bachelor of Science degrees (abbreviated "SB") were granted, the only type of undergraduate degree MIT now awards. In the 2011 fall term, among students who had designated a major, the School of Engineering was the most popular division, enrolling 63% of students in its 19 degree programs, followed by the School of Science (29%), School of Humanities, Arts, & Social Sciences (3.7%), Sloan School of Management (3.3%), and School of Architecture and Planning (2%). The largest undergraduate degree programs were in Electrical Engineering and Computer Science (), Computer Science and Engineering (), Mechanical Engineering (), Physics (), and Mathematics ().
https://en.wikipedia.org/wiki?curid=18879
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Sunlight is the main input to Earth's energy budget which accounts for its temperature and climate stability. Sunlight may be stored as gravitational potential energy after it strikes the Earth, as (for example when) water evaporates from oceans and is deposited upon mountains (where, after being released at a hydroelectric dam, it can be used to drive turbines or generators to produce electricity). Sunlight also drives most weather phenomena, save a few exceptions, like those generated by volcanic events for example. An example of a solar-mediated weather event is a hurricane, which occurs when large unstable areas of warm ocean, heated over months, suddenly give up some of their thermal energy to power a few days of violent air movement.
https://en.wikipedia.org/wiki?curid=9649
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All of the Gripen's avionics are fully integrated using five MIL-STD-1553B digital data buses, in what is described as "sensor fusion". The total integration of the avionics makes the Gripen a "programmable" aircraft, allowing software updates to be introduced over time to increase performance and allow for additional operational roles and equipment. The Ada programming language was adopted for the Gripen, and is used for the primary flight controls on the final prototypes from 1996 onwards and all subsequent production aircraft. The Gripen's software is continuously being improved to add new capabilities, as compared to the preceding Viggen, which was updated only in an 18-month schedule.
https://en.wikipedia.org/wiki?curid=87577
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The university offers bachelor, masters (and similar degree 'Specialist'), and post-graduate degrees in physics, mathematics, computer science and other areas. MEPhI facilities include a 2.5 MW (thermal) pool-type research reactor and Neutrino Water Detector NEVOD. The university has about 35,000 students at branches in Moscow and other towns. In Moscow are around 7,500 students (including over 1300 foreigners). It normally takes 4 - 5.5 (some sub-departments take six) years for a student to graduate from MEPhI. The curriculum of the first two years consists exclusively of required courses (core), with emphasis on mathematics, physics, experimental work and English. After the two first years of studying students on a competition basis enroll to the sub-departments which specialize in different branches of physics, computer science, information security, mathematics, etc.
https://en.wikipedia.org/wiki?curid=1145154
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Approximately 32% of people with Ashkenazi Jewish ancestry are in haplogroup K, with about 21% in K1a1b1a alone. This high percentage points to a genetic bottleneck occurring around the years 800-1000 under which K1a1b1a was particularly affected since K1a1b1a carriers' proportions of founder alleles and pathogenic variants were higher than in carriers of other haplogroups and the K1a1b1a carriers had longer total lengths for runs of homozygosity compared to carriers of other haplogroups. Ashkenazi mtDNA K clusters into six subclades: K1a1b1*, K1a1b1a, K1a4a, K1a9, K2a*, and K2a2a1. Several of these have Middle Eastern origins. A 2013 study had suggested that K1a1b1a, K1a9, and K2a2a1 could have originated from Western Europe. However, K1a9 is shared with non-Jews in Syria and Iran and K2a2a is shared with Mizrahi Jews from the Caucasus and Muslims on the Arabian Peninsula although K2a2a1 is also in Italy and the Iberian Peninsula. K1a4a is found in Syria and Turkey but also found in non-Jewish Europeans, including Greeks and Italians. Some of these kinds of matches to K haplogroups could support the contention that some of these individual female ancestors came from a Hebrew/Levantine mtDNA pool, whose descendants lived in Europe.
https://en.wikipedia.org/wiki?curid=4143444
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More recent ecoimmunological research has focused on host pathogen defences traditionally considered "non-immunological", such as pathogen avoidance, self-medication, symbiont-mediated defenses, and fecundity trade-offs. Behavioural immunity, a phrase coined by Mark Schaller, specifically refers to psychological pathogen avoidance drivers, such as disgust aroused by stimuli encountered around pathogen-infected individuals, such as the smell of vomit. More broadly, "behavioural" ecological immunity has been demonstrated in multiple species. For example, the Monarch butterfly often lays its eggs on certain toxic milkweed species when infected with parasites. These toxins reduce parasite growth in the offspring of the infected Monarch. However, when uninfected Monarch butterflies are forced to feed only on these toxic plants, they suffer a fitness cost as reduced lifespan relative to other uninfected Monarch butterflies. This indicates that laying eggs on toxic plants is a costly behaviour in Monarchs which has probably evolved to reduce the severity of parasite infection.
https://en.wikipedia.org/wiki?curid=14959
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In the east around 325, Shapur II regained the upper hand against the Kushano-Sasanian Kingdom and took control of large territories in areas now known as Afghanistan and Pakistan. Cultural expansion followed this victory, and Sasanian art penetrated Transoxiana, reaching as far as China. Shapur, along with the nomad King Grumbates, started his second campaign against the Romans in 359 and soon succeeded in retaking Singara and Amida. In response the Roman emperor Julian struck deep into Persian territory and defeated Shapur's forces at Ctesiphon. He failed to take the capital, however, and was killed while trying to retreat to Roman territory. His successor Jovian, trapped on the east bank of the Tigris, had to hand over all the provinces the Persians had ceded to Rome in 298, as well as Nisibis and Singara, to secure safe passage for his army out of Persia.
https://en.wikipedia.org/wiki?curid=5876413
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The chemical modification of recycled fibres aimed at the creation of a new generation of packaging papers characterized for being more recyclable, less hygroscopic, stiff and durable. The high recycling rate of papers in Europe (which is at the level of 72%) and the consequent importance that recycling has for the circular economy, were at the basis of this study. Paper products form part of an integrated carbon cycle based on the photosynthetic conversion of water, carbon dioxide, nutrients and solar energy into renewable wood-based biomass. Once consumed, paper may be recovered and used again either as a source of secondary fibres, to produce recycled paper or as bio-fuel. Fibre packages or corrugated containers made from corrugated board were the ones that were dealt with in the project, as they are considered as being the most prominent structural application of paper.
https://en.wikipedia.org/wiki?curid=48692630
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Ethical concerns of both travelers and academic groups include fear of humiliation due to the disclosure of anatomic or medical details, exposure to a low level of radiation (in the case of backscatter X-ray technology), violation of modesty and personal privacy, clarity of operating procedures, the use of this technology to discriminate against groups, and potential misuse of this technology for reasons other than detecting concealed objects. Also people with religious beliefs that require them to remain physically covered (arms, legs, face etc.) at all times will be unable and morally opposed to stepping inside of this virtually intrusive scanning technology. The Centre for Society, Science and Citizenship have discussed their ethical concerns including the ones mentioned above and suggest recommendations for the use of this technology in their report titled "Whole Body Imaging at airport checkpoints: the ethical and policy context" (2010).
https://en.wikipedia.org/wiki?curid=699052
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Packet switching allows delivery of variable bit rate data streams, realized as sequences of packets, over a computer network which allocates transmission resources as needed using statistical multiplexing or dynamic bandwidth allocation techniques. As they traverse networking hardware, such as switches and routers, packets are received, buffered, queued, and retransmitted (stored and forwarded), resulting in variable latency and throughput depending on the link capacity and the traffic load on the network. Packets are normally forwarded by intermediate network nodes asynchronously using first-in, first-out buffering, but may be forwarded according to some scheduling discipline for fair queuing, traffic shaping, or for differentiated or guaranteed quality of service, such as weighted fair queuing or leaky bucket. Packet-based communication may be implemented with or without intermediate forwarding nodes (switches and routers). In case of a shared physical medium (such as radio or 10BASE5), the packets may be delivered according to a multiple access scheme.
https://en.wikipedia.org/wiki?curid=43339
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All the Vostok cosmonauts toured extensively, but Tereshkova most of all; she made 42 trips abroad between 1963 and 1970. On 1 October 1963, Tereshkova arrived in Havana, Cuba, and met Fidel Castro. She toured the country which at the time was dealing with effects of Hurricane Flora. The following month she presented a silver cup, which went to the team from the Soviet Union who won gold in all five boat classes, at the women's 1963 European Rowing Championships held in Khimki near Moscow. By February 1964, Tereshkova was pregnant when she visited Elizabeth II of the United Kingdom who was also pregnant at the time. Except for a few-months break that year, Tereshkova went on a continuous and exhausting world tour, returning to her public duties only two months after the birth of her daughter.
https://en.wikipedia.org/wiki?curid=192196
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UConn lost regular season games against unranked Georgia Tech, Oregon, and Villanova, while losing to No. 6 Louisville in December. A healthy UConn dominated the Big East Tournament, defeating Villanova in the finals. In the NCAA Tournament, the No. 2 seed Huskies beat Mercer and struggled on their home court against a physical UCF team. At the Bridgeport regional, UConn defeated Indiana, then emerged victorious in a game that announcers called an "instant classic", a two-overtime 91–87 contest against No. 1 seed NC State. In a Final Four contest against Stanford, UConn out-rebounded the taller Cardinal squad and the Huskies' stifling defense held the defending national champions to a 34.8% shooting percentage to advance to this final with a 63–58 win.
https://en.wikipedia.org/wiki?curid=70426441
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It then described diseases associated with each season. For example, in spring many people began having mild fevers which, in some cases, caused hemorrhage. The hemorrhage was rarely fatal. Swelling next to both ears was also common. Coughs and sore throats accompanied the other symptoms. Based on modern knowledge, this disease was mumps, which causes salivary glands under the ears to swell. It is remarkable that this ancient work describes symptoms so vividly that modern doctors can diagnose the cause a thousand years later. This section of the Hippocratic Corpus, described that when looking at human disease and the health of humans, you must look at the seasons, winds and orientation of places, the nature of the water, the nature of the soil and the lifestyle of the inhabitants of a particular city.
https://en.wikipedia.org/wiki?curid=570856
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Watson graduated with a first class BSc in physics from Imperial College London in 1975. He then became a PhD student of James Lovelock, originator of the Gaia hypothesis of Earth regulation, at the University of Reading. He and Lovelock introduced the Daisyworld model in 1983, showing how ecological competition between hypothetical "daisies" could affect planetary albedo and regulate environmental temperature. Watson and his students have subsequently developed "a priori" models for the regulation of atmospheric composition through geological time. He has applied the weak Anthropic Principle to evolution on Earth, suggesting that long-term regulation of the Earth’s temperature and environment may be a necessary pre-requisite to allow sufficient time for the evolution of complex life and intelligence, rather than an intrinsic property of the biosphere as Lovelock proposed.
https://en.wikipedia.org/wiki?curid=15046175
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Sequencing of the virus from Merkel cell cancers reveals that it generally has tumor-specific mutations that truncate the MCV T antigen. These mutations (which are not found in native virus obtained from nontumor sites) eliminate the T antigen helicase, preventing the integrated virus from replicating independently from the host cancer cell. The tumor is therefore a "dead-end host" for MCV. Normally, the virus exists as circular episome (or plasmid) within the cell and its DNA is packaged into viral capsids and transmitted to other cells. In tumors, the viral DNA has broken and become integrated into human DNA within the tumor, so that the virus is no longer transmissible. The integrated virus cannot be excised from the host cell and it must replicate as the host cell is replicated. Examination of infected tumors reveals that the majority have a clear monoclonal pattern, indicating that the virus integrated into a single cell before it began its cancerous expansion. For this reason, there is very strong evidence that MCV causes some, but not all, Merkel cell carcinomas. MCV can also be found in healthy tissues from people without Merkel cell carcinoma. A complete MCV genome (MCV-HF) was designed from multiple tumor-type MCV genomes and examined with successful replication capability in vitro. The identical sequences were found in human normal skins. While the precise prevalence of infection is unknown in humans, it is likely that most infections do not cause cancers.
https://en.wikipedia.org/wiki?curid=16814276
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The choanoflagellates were included in Chrysophyceae until Hibberd, 1975. Recent molecular phylogenetic reconstruction of the internal relationships of choanoflagellates allows the polarization of character evolution within the clade. Large fragments of the nuclear SSU and LSU ribosomal RNA, alpha tubulin, and heat-shock protein 90 coding genes were used to resolve the internal relationships and character polarity within choanoflagellates. Each of the four genes showed similar results independently and analysis of the combined data set (concatenated) along with sequences from other closely related species (animals and fungi) demonstrate that choanoflagellates are strongly supported as monophyletic and confirm their position as the closest known unicellular living relative of animals.
https://en.wikipedia.org/wiki?curid=220443
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Gray bats consume a variety of insects including Coleoptera (beetles), Diptera (flies), Ephemeroptera (mayflies, of which gray bats consume at least six species), Lepidoptera (moths), Neuroptera (net-winged insects), Trichoptera (caddis flies), and Plecoptera (stoneflies). Juveniles have a tendency to forage more in woodlands and eat more beetles than adults, perhaps they provide a greater energy reward per unit of capture effort. For example, beetles provide 1900–2800 calories/g wet weight versus 800–1400 calories/g wet weight for mayflies. "M. grisescens" juveniles also eat a less diverse diet than adults, possibly because juveniles are more dependent on high concentrations of prey or swarming prey. Gray bats are believed to be part opportunists, and part selective eaters. (Outside of captivity, gray bats are limited by the sporadic emergences of potential prey. When prey emerges, there is only an abundance of a few taxa at any given time. The available taxa change based on the time of night, the month, and the time during the activity season.) In their natural habitats, gray bats appear to attack any moving target that is of appropriate size, consistent with optimal foraging theory that predicts palatable insects of an appropriate size should be eaten when encountered. In captivity, under controlled laboratory conditions, however, insectivorous bats used echolocation to discriminate heavily among potential prey based on shape and texture of a target. This lack of discrimination may be because of the rapid flight of bats and the short range at which prey can be detected using echolocation, allowing bats only a fraction of a second after detection to capture prey. However, gray bats are believed to discriminate somewhat between insects when foraging in their natural habitat, consuming higher numbers of Lepidoptera, Coleoptera, Diptera, and in some populations Trichoptera, than their proportional prevalence would have otherwise indicated without selective foraging. Because of this tendency to select prey while being largely opportunistic, gray bats have been dubbed ‘selective opportunists’. Scientists believe that food moves quickly through the digestive tract of "M. grisescens", with feces being purged from the body within 1–2 hours after ingestion.
https://en.wikipedia.org/wiki?curid=827802
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