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The Ju 87 operated with considerable success in close air support and anti-shipping roles at the outbreak of World War II. It led air assaults in the invasion of Poland in September 1939. Stukas proved critical to the rapid conquest of Norway, the Netherlands, Belgium and France in 1940. Though sturdy, accurate, and very effective against ground targets, the Stuka was, like many other dive bombers of the period, vulnerable to fighter aircraft. During the Battle of Britain of 1940-1941, its lack of manoeuvrability, speed and defensive armament meant that it required a heavy fighter escort to operate effectively.
https://en.wikipedia.org/wiki?curid=16590
330,049
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According to a 2012 poll by Innovative Research Group, on behalf of the Canadian Nuclear Association, 37% of Canadians are in favour of nuclear power, while 53% oppose it. Both of these figures represent a drop from 2011 (38% and 56% respectively), and the population that neither supports nor opposes or did not know their opinion has grown to 9%. Support ranges from a high of 54% in Ontario to a low of 12% in Quebec. Other notable demographic details include men being generally more supportive of nuclear power than women, and older populations being slightly more supportive than younger populations. There was not a significant change in opposition to nuclear power in Canada following the March 2011 events at Japan's Fukushima Daiichi Nuclear Power Station (from 54% to 56%), and the issue was followed at least somewhat closely by 70% of Canadians polled.
https://en.wikipedia.org/wiki?curid=3778479
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Three more residence halls will temporarily close in the Fall of 2017: Center, Responsibility, and Discovery. Previously it was announced Respect, Excellence, Schurz and McDavid wouldn't operate in the Fall unless there was sufficient demand to reopen some of them. Combined, the seven halls are capable of housing about 1,500 students. The closures are estimated to save about $2 million, largely through reduced utility costs. The university says two of the closed halls also could get some use as guest and conference housing. The temporary closures come after freshman enrollment dropped 24 percent for this academic year. The declining enrollment precipitated a budget plan to cut 400 jobs, but most of them are from those resigning or retiring, so less than 100 actual jobs will be eliminated for the 2018 fiscal year.
https://en.wikipedia.org/wiki?curid=23964683
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Convergence has also raised several debates about classification of certain telecommunications services. As the lines between data transmission, and voice and media transmission are eroded, regulators are faced with the task of how best to classify the converging segments of the telecommunication sector. Traditionally, telecommunication regulation has focused on the operation of physical infrastructure, networks, and access to network. No content is regulated in the telecommunication because the content is considered private. In contrast, film and Television are regulated by contents. The rating system regulates its distribution to the audience. Self-regulation is promoted by the industry. Bogle senior persuaded the entire industry to pay 0.1 percent levy on all advertising and the money was used to give authority to the Advertising Standards Authority, which keeps the government away from setting legislature in the media industry.
https://en.wikipedia.org/wiki?curid=206586
837,974
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With a plane wavefront incident, the overlap of the two reflected beams shows interference fringes with a spacing of formula_1, where formula_2 is the spacing perpendicular to shear, "formula_3" is the wavelength of the beam, "n" the refractive index, and "formula_4" the wedge angle. This equation makes the simplification that the distance from the wedged shear plate to the observation plane is small relative to the wavefront radius of curvature at the observation plane. The fringes are equally spaced and will be exactly perpendicular to the wedge orientation and parallel to a usually present wire cursor aligned along the beam axis in the shearing interferometer. The orientation of the fringes varies when the beam is not perfectly collimated. In the case of a noncollimated beam incident on a wedged shear plate, the path difference between the two reflected wavefronts is increased or decreased from the case of perfect collimation depending on the sign of the curvature. The pattern is then rotated and the beam's wavefront radius of curvature "formula_5" can be calculated: formula_6, with "formula_7" the shear distance, "formula_2" the fringe distance, "formula_3" the wavelength and "formula_10" the angular deviation of the fringe alignment from that of perfect collimation. If the spacing normal to the fringes is used instead, this equation becomes formula_11, where formula_12 is the fringe spacing normal to the fringes.
https://en.wikipedia.org/wiki?curid=2904877
1,242,050
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While a fetus of ectopic pregnancy is typically not viable, very rarely, a live baby has been delivered from an abdominal pregnancy. In such a situation the placenta sits on the intra-abdominal organs or the peritoneum and has found sufficient blood supply. This is generally bowel or mesentery, but other sites, such as the renal (kidney), liver or hepatic (liver) artery or even aorta have been described. Support to near viability has occasionally been described, but even in Third World countries, the diagnosis is most commonly made at 16 to 20 weeks' gestation. Such a fetus would have to be delivered by laparotomy. Maternal morbidity and mortality from extrauterine pregnancy are high as attempts to remove the placenta from the organs to which it is attached usually lead to uncontrollable bleeding from the attachment site. If the organ to which the placenta is attached is removable, such as a section of bowel, then the placenta should be removed together with that organ. This is such a rare occurrence that true data is unavailable and reliance must be made on anecdotal reports. However, the vast majority of abdominal pregnancies require intervention well before fetal viability because of the risk of bleeding.
https://en.wikipedia.org/wiki?curid=54309
63,479
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According to Jains, the consequences of karma are inevitable. The consequences may take some time to take effect but the "karma" is never fruitless. The latent karma becomes active and bears fruit when the supportive conditions arise. A great part of attracted karma bears its consequences with minor fleeting effects, as generally most of our activities are influenced by mild negative emotions. However, those actions that are influenced by intense negative emotions cause an equally strong karmic attachment which usually does not bear fruit immediately. It takes on an inactive state and waits for the supportive conditions—like proper time, place, and environment—to arise for it to manifest and produce effects. If the supportive conditions do not arise, the respective karmas will manifest at the end of maximum period for which it can remain bound to the soul. These supportive conditions for activation of latent karmas are determined by the nature of karmas, intensity of emotional engagement at the time of binding karmas and our actual relation to time, place, surroundings. There are certain laws of precedence among the karmas, according to which the fruition of some of the karmas may be deferred but not absolutely barred.
https://en.wikipedia.org/wiki?curid=13323241
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Modern heat-seeking missiles utilise imaging infrared ("IIR"), where the IR/UV sensor is a focal plane array which is able to produce an image in infra-red, much like the CCD in a digital camera. This requires much more signal processing but can be much more accurate and harder to fool with decoys. In addition to being more flare-resistant, newer seekers are also less likely to be fooled into locking onto the sun, another common trick for avoiding heat-seeking missiles. By using the advanced image processing techniques, the target shape can be used to find its most vulnerable part toward which the missile is then steered. All western Short-range air-to-air missiles such as the AIM-9X Sidewinder and ASRAAM use imaging infrared seekers, as well as the Chinese PL-10 SRAAM, Taiwanese TC-1, Israeli Python-5 and Russian R-74M/M2.
https://en.wikipedia.org/wiki?curid=1396771
281,155
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ACS Central Science is a monthly peer-reviewed open access scientific journal covering chemistry and related fields. Its title refers to the phrase "central science", which has long been used to describe the role played by chemistry in connecting the physical and life sciences. Established in 2015, it is the first fully open-access journal published by ACS Publications, the American Chemical Society's publishing arm. The editor-in-chief is Carolyn R. Bertozzi (Stanford University). "ACS Central Science" is highly selective, publishing only 100-200 papers/year deemed by editors and reviewers to be of exceptional interest and importance (compared to approximately 3,000 articles for JACS). It is entirely open access, with no publishing charges for authors as well as no subscription fees for readers.
https://en.wikipedia.org/wiki?curid=61860248
1,761,558
9,011
President Obama's plan was to develop American private spaceflight capabilities to get astronauts to the International Space Station, replace Russian Soyuz capsules, and use Orion capsules for ISS emergency escape purposes. During a speech at the Kennedy Space Center on April 15, 2010, Obama proposed a new heavy-lift vehicle (HLV) to replace the formerly planned Ares V. In his speech, Obama called for a crewed mission to an asteroid as soon as 2025, and a crewed mission to Mars orbit by the mid-2030s. The NASA Authorization Act of 2010 was passed by Congress and signed into law on October 11, 2010. The act officially canceled the Constellation program.
https://en.wikipedia.org/wiki?curid=18426568
9,007
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Under the same category of SRBM, the second project which was codename Shaheen, was widely pursued and developed by the National Defence Complex (NDC)– a spinoff of PAEC. The Shaheen is a series of solid-fuelled missiles and expended well to SRC, NESCOM, DESTO, and Margalla Electronics. Despite many technological set backs and learning from India's developmental experience of the Agni-II, the project continues to evolve and produced the Shaheen-I which entered in the service in 1999. The Shaheen project produces three variants that are considered to be in the MRBM range. The Shaheen-II has a range of 2,500 km with a capacity of carrying payload of 1050kg. Its third variant, the Shaheen-III, rumored to be underdeveloped and is an IRBM range. No official confirmation of the project is known but only the media reports. In January 2017, the Ababeel, a development of the Shaheen-III with multiple independently targetable reentry vehicles (MIRV), was tested. This is a Shaheen-III airframe with an enlarged payload fairing and slightly shorter range of 2,200 km. The intention of the MIRV system is to counteract Indian BMD.
https://en.wikipedia.org/wiki?curid=28072082
1,145,818
1,054,523
Muhlenbergia capillaris, commonly known as the hairawn muhly, is a perennial sedge-like plant that grows to be about tall and wide. The plant includes a double layer; green, leaf-like structures surround the understory, and purple-pink flowers outgrow them from the bottom up. The plant is a warm-season grass, meaning that leaves begin growth in the summer. During the summer, the leaves stay green, but they morph during the fall to produce a more copper color. The seasonal changes also include the flowers, as they grow out during the fall and stay healthy till the end of autumn. The muhly grows along the border of roads and on plain prairies. The grass clumps into herds, causing bush-like establishments in the area the hairawn muhly inhabits. The flowers are very feathery and add a cloudlike appearance to the top of the grass. It is native to eastern North America and can be used for a multitude of purposes, including ornamental gardening and farming. It was voted 2012 plant of the year by the Garden Club of America.
https://en.wikipedia.org/wiki?curid=35694513
1,053,976
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A pathogen’s path to infection begins with the cell wall; the proteins that connect the cell wall to the plasma membrane are the initial mediators in the pathogen response. WAK1 is induced in a plant’s pathogenic response along with other pathogen-related proteins that function in protection. Wak1 is present in Arabidopsis plant tissue, with WAK1 mRNA expression more abundant in plant stem, leaves than in the roots and its extracellular domain contains epidermal growth repeats that facilitates cell signaling. Heat and salt do not have an effect in WAK1 production within tissues, however wounding is significant as it causes the expression of a WAK1 message by 2,2-dichloroisonicotinic acid (INA), a natural salicylate (SA) in the signal transduction pathway in the plant response to infection. Since WAK1 is vital to the survival of a plant in response to pathogens, it simultaneously confers resistant to SA to a point where the plant can survive exposure to high levels of SA. Increased resistance to SA through WAK1 expression can only be conferred through ectopic expression of an entire WAK1 protein or kinase domain. This ultimately means that inducing WAK1 expression causes decreased SA levels and a reduced toxicity, hence protection, demonstrating a role of WAK1 in regulating pathogenic attacks.
https://en.wikipedia.org/wiki?curid=13415231
2,106,339
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Du Châtelet invited Voltaire to live at her country house at Cirey in Haute-Marne, northeastern France, and he became her long-time companion. There she studied physics and mathematics and published scientific articles and translations. To judge from Voltaire's letters to friends and their commentaries on each other's work, they lived together with great mutual liking and respect. As a literary rather than scientific person, Voltaire implicitly acknowledged her contributions to his 1738 "Elements of the Philosophy of Newton". This was through a poem dedicated to her at the beginning of the text and in the preface, where Voltaire praised her study and contributions. The book's chapters on optics show strong similarities with her own "Essai sur l'optique". She was able to contribute further to the campaign by a laudatory review in the "Journal des savants".
https://en.wikipedia.org/wiki?curid=1002045
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Current research shows that the maximum firing rate of spatial view cells is obtained when the test agent is allowed to explore the environment freely. Tests in which the monkey was not allowed to have active locomotion provided very few results of spatial view cells being detected in the hippocampus. Majority of the experiments conducted for spatial view cells involved the use of macaque monkeys as test subjects. These types of cells are identified by monitoring the hippocampus of the monkeys while the brains are stimulated by presenting various images and objects in the monkey's vision. Various researchers use different methodologies in sync with the experiment being conducted in order to identify these spatial view cells. For example, in a delayed spatial response task, the monkey is shown a stimulus on one side of a screen and then the stimulus is taken away. After a short while, the stimulus is again presented to the monkey in the same location and the firing of the cell in the hippocampus that is specifically associated with the location at which the monkey is looking and is independent of the location of the monkey helps identify the spatial view cell. The monkeys in this of experiment are encouraged by rewarding them with fruit juice when they correctly identify the same object in the same location twice in a row and if they get it incorrect, the monkeys receive a saline taste.
https://en.wikipedia.org/wiki?curid=8297063
2,146,348
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During the same period, Soviet military engineer P.K. Oshchepkov, in collaboration with the Leningrad Electrotechnical Institute, produced an experimental apparatus, RAPID, capable of detecting an aircraft within 3 km of a receiver. The Soviets produced their first mass production radars RUS-1 and RUS-2 Redut in 1939 but further development was slowed following the arrest of Oshchepkov and his subsequent gulag sentence. In total, only 607 Redut stations were produced during the war. The first Russian airborne radar, Gneiss-2, entered into service in June 1943 on Pe-2 dive bombers. More than 230 Gneiss-2 stations were produced by the end of 1944. The French and Soviet systems, however, featured continuous-wave operation that did not provide the full performance ultimately synonymous with modern radar systems.
https://en.wikipedia.org/wiki?curid=25676
62,062
27,417
At the end of 2005, after five overall victories for the R8, and six to its V8 turbo engine, Audi took on a new challenge by introducing a diesel engined prototype known as the R10 TDI. Although not the first diesel to race, it was the first to win at Le Mans. This era saw other alternative fuel sources used, including bio-ethanol. At the same time, Peugeot decided to follow Audi's lead and pursue a diesel entry in 2007 with their 908 HDi FAP. In the 2008 race between the Audi R10 TDI and the Peugeot 908 HDi FAP, the Audi won by a margin of fewer than 10 minutes. For the 2009 24 Hours of Le Mans, Peugeot introduced a new energy-recovery system similar to the KERS used in Formula One. Aston Martin entered the LMP1 category, but still raced in GT1 with private teams. Audi returned with the new R15 TDI, but Peugeot prevailed in its first overall win since 1993.
https://en.wikipedia.org/wiki?curid=1401596
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Around 1989, several laboratories were successful in producing "transgenic plants" which produced elevated amounts of different phytochromes ("overexpression"). In all cases the resulting plants had conspicuously short stems and dark green leaves. Harry Smith and co-workers at Leicester University in England showed that by increasing the expression level of phytochrome A (which responds to far-red light), shade avoidance responses can be altered. As a result, plants can expend less energy on growing as tall as possible and have more resources for growing seeds and expanding their root systems. This could have many practical benefits: for example, grass blades that would grow more slowly than regular grass would not require mowing as frequently, or crop plants might transfer more energy to the grain instead of growing taller.
https://en.wikipedia.org/wiki?curid=652209
631,929
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Sargent is regarded as the "father" of Process Systems Engineering (PSE). Through his academic and research activities Sargent built up a school of PSE that is now widely spread all over the world. His contributions to the area are known worldwide and considered important pillars to the PSE area adding up to a collection of outstanding achievements over the last 50 years. It is only when we learn of those whose academic origins can be traced back to Sargent, do we realise the full contribution he has already made, not only through his own work, but by instilling his enthusiasm for excellence into those who later have taken up the challenge. The interests of this group are reflections of Sargent's focus on process modelling, simulation, optimisation and control, a field, which is now called PSE. Sargent's vision, leadership and guidance has led the establishment of PSE as the development of systematic techniques for process modelling, design, and control.
https://en.wikipedia.org/wiki?curid=30221926
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The study was completed in May 2007, with the Quad TiltRotor selected for further development. However, additional armor on Future Combat Systems manned ground vehicles caused their weight to increase from 20 tons to 27 tons, requiring a larger aircraft. In mid-2008, the U.S. Army continued the Joint Heavy Lift (JHL) studies with new contracts to the Bell-Boeing and Karem Aircraft/Lockheed Martin teams. The teams were to modify their designs to reach new JHL specifications. JHL became part of the new US Air Force/Army Joint Future Theater Lift (JFTL) program in 2008. In mid-2010, the US DoD was formulating a vertical lift aircraft plan with JFTL as a part. The DoD also requested information from the aerospace industry on technologies for JFTL in October 2010.
https://en.wikipedia.org/wiki?curid=9471443
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When a diver holds their breath during an ascent the reduction in pressure will cause the gas to expand and the lungs will also have to expand to continue to contain the gas. If the expansion exceeds the normal capacity of the lungs, they will continue to expand elastically until the tissues reach their tensile strength limit, after which any increase in pressure difference between the gas in the lungs and the ambient pressure will cause the weaker tissues to rupture, releasing gas from the lungs into any permeable space exposed by the damaged tissue. This could be the pleural space between the lung and the chest walls, between the pleural membranes, and this condition is known as pneumothorax. The gas could also enter the interstitial spaces within the lungs, the neck and larynx, and the mediastinal space around the heart, causing interstititial or mediastinal emphysema, or it could enter the blood vessels of the venous pulmonary circulation via damaged alveolar capillaries, and from there reach the left side of the heart, from which they will be discharged into the systemic circulation. On the way out through the aorta the gas may be entrained in blood flowing into the carotid or basilar arteries. If these bubbles cause blockage in blood vessels, this is arterial gas embolism. Sufficient pressure difference and expansion to cause this injury can occur from depths as shallow as .
https://en.wikipedia.org/wiki?curid=489838
1,212,182
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At sea, 97% of marine snail species, 89% of clams, and 50% of echinoderms of the Gulf Coast did not survive past the earliest Oligocene. New species evolved, but the overall diversity diminished. Cold-water mollusks migrated around the Pacific Rim from Alaska and Siberia. The marine animals of Oligocene oceans resembled today's fauna, such as the bivalves. Calcareous cirratulids appeared in the Oligocene. The fossil record of marine mammals is a little spotty during this time, and not as well known as the Eocene or Miocene, but some fossils have been found. The baleen whales and toothed whales had just appeared, and their ancestors, the archaeocete cetaceans began to decrease in diversity due to their lack of echolocation, which was very useful as the water became colder and cloudier. Other factors to their decline could include climate changes and competition with today's modern cetaceans and the requiem sharks, which also appeared in this epoch. Early desmostylians, like "Behemotops", are known from the Oligocene. Pinnipeds appeared near the end of the epoch from an otter-like ancestor.
https://en.wikipedia.org/wiki?curid=22286
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"Tullibee" was a type of nuclear-powered SSK; technologically very successful, intentionally slow but ultra-quiet with turbo-electric drive. Her unexpectedly high cost compared with the "Thresher" proved it was impossible to build a low-cost nuclear SSK (several nuclear reactor features could not be scaled down beyond a certain point, including radiation shielding). This result coupled with her lower performance was judged to be not cost-effective and the type was not repeated; the Navy decided to merge the hunter-killer role with the attack submarines, making the terms interchangeable. "Thresher" was faster and had an increased diving depth, carried twice as many torpedoes, included comparable sound silencing improvements, and was commissioned only nine months later.
https://en.wikipedia.org/wiki?curid=228508
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The progress of the Apollo program alarmed the chief designers, who each advocated for his own program as the response. Multiple, overlapping designs received approval, and new proposals threatened already approved projects. Due to Korolev's "singular persistence", in August 1964—more than three years after the United States declared its intentions—the Soviet Union finally decided to compete for the moon. It set the goal of a lunar landing in 1967—the 50th anniversary of the October Revolution—or 1968. At one stage in the early 1960s the Soviet space program was actively developing 30 projects for launchers and spacecraft. With the fall of Krushchev in 1964, Korolev was given complete control of the crewed program.
https://en.wikipedia.org/wiki?curid=723059
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During the 19th century, graphite's uses greatly expanded to include stove polish, lubricants, paints, crucibles, foundry facings, and pencils, a major factor in the expansion of educational tools during the first great rise of education for the masses. The British Empire controlled most of the world's production (especially from Ceylon), but production from Austrian, German, and American deposits expanded by mid-century. For example, the Dixon Crucible Company of Jersey City, New Jersey, founded by Joseph Dixon and partner Orestes Cleveland in 1845, opened mines in the Lake Ticonderoga district of New York, built a processing plant there, and a factory to manufacture pencils, crucibles and other products in New Jersey, described in the "Engineering & Mining Journal" 21 December 1878. The Dixon pencil is still in production.
https://en.wikipedia.org/wiki?curid=12366
87,640
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During the tenure of Smith, the school also gained university status from the South Carolina General Assembly, becoming South Carolina State University in February 1992. In 1993, Barbara Hatton became the school's first female president and created many improvements for the campus, such as the 1994 renovation of Oliver C. Dawson Bulldog Stadium, constructing new suites and a larger press box, as well as increasing its capacity to 22,000. Hatton also spearheaded the creation of a plaza which resides in front of the Student Union and passes by several dorms and buildings in the central portion of the campus. Under SC State's next president, Leroy Davis, South Carolina State University celebrated its 100th anniversary in 1996, and the school constructed a Fine Arts Center in 1999, giving the Art and Music departments a new home.
https://en.wikipedia.org/wiki?curid=574357
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In some settings, structural gender inequity is associated with particular forms of violence, marginalization, and oppression against females. This includes violent assault by men, child sexual abuse, strict regulation of women's behavior and movement, female genital mutilation, and exploitative, forced labor. Women and girls are also vulnerable to less well-documented forms of abuse or exploitation, such as human trafficking or "honor killings" for perceived behavioral transgressions and deviation of their social roles. These acts are associated with a wide range of health problems in women such as physical injuries, unwanted pregnancies, abortions, mental disorders such as depression, and anxiety, substance abuse, and sexually transmitted infections, all of which can potentially lead to premature death.
https://en.wikipedia.org/wiki?curid=38846583
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Before entering any school of higher education for which there are more applicants than places offered, the applicants have to pass entrance examinations. These examinations take very different forms at particular schools. The "maturita" results of the applicant are usually also taken into account when evaluating whether he can become student of the school. Since the number of branches of study and of schools of higher education increased considerably in the course of the late 18th century (although at the cost of quality of the studies), the general percentage of those not being accepted to these schools decreased considerably over the same time period. Also, an increasing number of Slovaks studies abroad, especially in the Czech Republic due to a low language barrier, a slightly better economic situation (and job perspectives) in that country, as well as similarities of the two educational systems. As a result, the percentage of Slovaks with higher education has increased considerably over the last decade.
https://en.wikipedia.org/wiki?curid=395130
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Multiple mammalian isoforms of the protein have been reported to date, difference rising by either the transcription of different enzymes or alternative splicing. While the structural core that catalyzes the PFK-2/FBPase-2 reaction is highly conserved across isoforms, the major differences arise from highly variable flanking sequences in the isoform amino and carboxyl terminals. Because these areas often contain phosphorylation sites, changes in amino acid composition or terminal length may result in vastly different enzyme kinetics and characteristics. Each variant differs in their primary tissue of expression, response to protein kinase regulation, and ratio of kinase/phosphatase domain activity. While multiple types of isozymes may consist in a tissue, isozymes are identified by their primary tissue expression and tissue of discovery below.
https://en.wikipedia.org/wiki?curid=2595710
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Insect blood or haemolymph's main function is that of transport and it bathes the insect's body organs. Making up usually less than 25% of an insect's body weight, it transports hormones, nutrients and wastes and has a role in, osmoregulation, temperature control, immunity, storage (water, carbohydrates and fats) and skeletal function. It also plays an essential part in the moulting process. An additional role of the haemolymph in some orders, can be that of predatory defence. It can contain unpalatable and malodourous chemicals that will act as a deterrent to predators. Haemolymph contains molecules, ions and cells; regulating chemical exchanges between tissues, haemolymph is encased in the insect body cavity or haemocoel. It is transported around the body by combined heart (posterior) and aorta (anterior) pulsations, which are located dorsally just under the surface of the body. It differs from vertebrate blood in that it does not contain any red blood cells and therefore is without high oxygen carrying capacity, and is more similar to lymph found in vertebrates.
https://en.wikipedia.org/wiki?curid=24104729
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Compared to the 6.8×43mm Special Purpose Cartridge, another round made to have increased stopping power over the 5.56 NATO, the 300 Blackout has different capabilities. The 300 BLK was designed with a specific shorter-range focus to have equal or more energy than the 7.62 Soviet and work reliably with suppressors. The earlier 6.8 SPC was simply designed to have more energy at all ranges than the 5.56×45mm. It has a relatively small projectile with a high velocity that maintains performance at range. At , the 300 BLK drops lower than the 6.8 SPC, while it drops lower at . The 6.8-round has a higher muzzle energy of due to its greater velocity, while the 300 BLK round has a muzzle energy of . Both rounds were made to be used in an easily converted AR-15. The 6.8 SPC has a more difficult conversion because it was designed around the obsolete .30 Remington cartridge, requiring a different bolt and decreasing standard magazine capacity. The 300 BLK was made specifically for ease of conversion, so the standard bolt will work and a magazine can be used to its full capacity, so the only change needed is the barrel and gas system.
https://en.wikipedia.org/wiki?curid=28997320
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The success of the unlicensed band in accommodating a range of wireless devices and services has led the FCC to consider opening further bands for unlicensed use. In contrast, the licensed bands are underutilized due to static frequency allocation. Realizing that CR technology has the potential to exploit the inefficiently utilized licensed bands without causing interference to incumbent users, the FCC released a Notice of Proposed Rule Making which would allow unlicensed radios to operate in the TV-broadcast bands. The IEEE 802.22 working group, formed in November 2004, is tasked with defining the air-interface standard for wireless regional area networks (based on CR sensing) for the operation of unlicensed devices in the spectrum allocated to TV service. To comply with later FCC regulations on unlicensed utilization of TV spectrum, the IEEE 802.22 has defined interfaces to the mandatory TV White Space Database in order to avoid interference to incumbent services.
https://en.wikipedia.org/wiki?curid=1000682
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Pathogens may be prokaryotic (archaea or bacteria), single-celled eukarya or viruses. Prokaryotic genomes have typically been easier to sequence due to smaller genome size compared to Eukarya. Due to this, there is a bias in reporting pathogenic bacterial behavior. Regardless of this bias in reporting, many of the dynamic genomic events are similar across all the types of pathogen organisms. Genomic evolution occurs via gene gain, gene loss, and genome rearrangement, and these "events" are observed in multiple pathogen genomes, with some bacterial pathogens experiencing all three. Pathogenomics does not focus exclusively on understanding pathogen-host interactions, however. Insight of individual or cooperative pathogen behavior provides knowledge into the development or inheritance of pathogen virulence factors. Through a deeper understanding of the small sub-units that cause infection, it may be possible to develop novel therapeutics that are efficient and cost-effective.
https://en.wikipedia.org/wiki?curid=21787394
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The near-time approach uses the recent fossil record (usually from the Late Pleistocene or the Holocene) to provide a long-term context to extant ecosystems dynamics. The fossil record is, in many cases, the only source of information on conditions previous to human impacts. These records can be used as reference baselines for comparisons in order to identify targets for restoration ecology, to analyze species responses to perturbations (natural and anthropogenic), understand historical species distributions and their variability, discriminate the factors that distinguish natural from non-natural changes in biological populations and identify ecological legacies only explicable by referring to past events or conditions.
https://en.wikipedia.org/wiki?curid=59573391
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As the development of a new main battle tank stalled with problems and cost escalating quickly, the M60A1 was forced to serve longer than originally intended with production lasting almost 20 years. In that time span, numerous product improvement programs were put forward. As the major changes were incorporated into the production line, the vehicle model designations were changed. The first of which was Top Loading Air Cleaner (TLAC) in 1971. This reduced dirt and dust ingestion, which increased engine life as well as allowing for easier servicing of the engine. Early TLAC panels were made from aluminum and were vulnerable to damage from small arms fire.
https://en.wikipedia.org/wiki?curid=470028
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2-Butoxyethanol is an organic compound with the chemical formula BuOCHOH (Bu = CHCHCHCH). This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol. As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. It is a known respiratory irritant and can be acutely toxic, but animal studies did not find it to be mutagenic, and no studies suggest it is a human carcinogen. A study of 13 classroom air contaminants conducted in Portugal reported a statistically significant association with increased rates of nasal obstruction and a positive association below the level of statistical significance with a higher risk of obese asthma and increased child BMI.
https://en.wikipedia.org/wiki?curid=2080887
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The measurement of 1/"f" noise spectrum in voltage or current is done in the same way as the measurement of other types of noises. Sampling spectrum analyzers take a finite-time sample from the noise and calculate the Fourier transform by FFT algorithm. Then, after calculating the squared absolute value of the Fourier spectrum, they calculate its average value by repeating this sampling process by a sufficiently large number of times. The resulting pattern is proportional to the power-density spectrum of the measured noise. It is then normalized by the duration of the finite-time sample and also by a numerical constant in the order of 1 to get its exact value. This procedure gives correct spectral data only deeply within the frequency window determined by the reciprocal of the duration of the finite-time sample (low-frequency end) and the digital sampling rate of the noise (high-frequency end). Thus the upper and the lower half decades of the obtained power density spectrum are usually discarded from the spectrum. Conventional spectrum analyzers that sweep a narrow filtered band over the signal have good signal-to-noise ratio (SNR), since they are narrow-band instruments. Unfortunately, these instruments do not operate at frequencies low enough to fully measure flicker noise. Sampling instruments are broadband, and hence high noise. They reduce the noise by taking multiple sample traces and averaging them. Conventional spectrum analyzers still have better SNR due to their narrow-band acquisition.
https://en.wikipedia.org/wiki?curid=6799095
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The construction of the Institute featured creative technical achievements for the era, including hollow block construction and poured reinforced concrete formed in a waffle slab with ribs. The National Film and Sound Archive has occupied the building since 1984. This organisation is widely regarded by the public for its efforts to conserve and promote Australian culture as represented in film, television, radio and sound recordings. The building houses items of enduring cultural significance to Australians. In addition to discs, films, videos, audio tapes, phonograph cylinders and wire recordings, the Archive's collection includes supporting documents and artefacts, such as photographic stills, transparencies, posters, lobby cards, publicity, scripts, costumes, props, memorabilia and sound, video and film equipment.
https://en.wikipedia.org/wiki?curid=17035961
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Statins, HMG-CoA reductase inhibitors, are competent in lowering cholesterol levels and reducing cardiac-related diseases. However, there have been controversies surrounding the potential of statins increasing the risk of new-onset diabetes mellitus (NOD). Experiments have demonstrated that glucose and cholesterol homeostasis are regulated by statins. The HMG-CoA reductase (HMGCR), converts HMG-CoA into mevalonic acid. Thus, when HMGCR activities are reduced, the cell associated cholesterols are also reduced. This results in the activation of SREBP-2-mediated signaling pathways. SREBP-2 activation for cholesterol homeostasis is crucial for the upregulation of low density lipoprotein (LDL) receptor (LDLR). The removal of LDL particles from blood circulation is enhanced when the number of LDLR on hepatocytes increases. Due to the removal of atherogenic lipoprotein particles, such as LDLs and intermediate density lipoproteins, HMGCR inhibitors have been proven to be efficient in reducing cardiovascular diseases from the blood circulation, which is represented by the reduction of LDL-cholesterol levels. In many studies, lipophilic statins are shown as more diabetogenic, possibly due to the fact that they can easily diffuse into cells and inhibit the production of isoprenoids which become more potent. Additionally, statins have been shown to change glucose levels as well.
https://en.wikipedia.org/wiki?curid=864596
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There is a growing body of peer-reviewed theoretical work on synthesizing diamond by mechanically removing/adding hydrogen atoms and depositing carbon atoms (a process known as mechanosynthesis). This work is slowly permeating the broader nanoscience community and is being critiqued. For instance, Peng et al. (2006) (in the continuing research effort by Freitas, Merkle and their collaborators) reports that the most-studied mechanosynthesis tooltip motif (DCB6Ge) successfully places a C carbon dimer on a C(110) diamond surface at both 300 K (room temperature) and 80 K (liquid nitrogen temperature), and that the silicon variant (DCB6Si) also works at 80 K but not at 300 K. Over 100,000 CPU hours were invested in this latest study. The DCB6 tooltip motif, initially described by Merkle and Freitas at a Foresight Conference in 2002, was the first complete tooltip ever proposed for diamond mechanosynthesis and remains the only tooltip motif that has been successfully simulated for its intended function on a full 200-atom diamond surface.
https://en.wikipedia.org/wiki?curid=19637
724,091
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Founded in 1903 and incorporated in New York as a US not-for-profit institution in 1926, in its initial years BIOS was a seasonal field station for visiting zoologists and biologists to take advantage of Bermuda's diverse marine environment. After the Second World War, BIOS became a year-round research center, anchored by the establishment in 1954 of Hydrostation 'S': regular deep ocean observations of a single point in the ocean that continue today, creating the longest continuous oceanic database in the world. During the following few decades, increasing numbers of visiting scientists brought an increased emphasis on biological and geological studies.
https://en.wikipedia.org/wiki?curid=11661821
1,849,881
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The predisposing conditions described in the previous paragraph can serve to enhance the ability of the plasmablasts in PBL to: avoid the host's immune surveillance; survive for prolonged periods, grow excessively, and acquire pro-malignant gene abnormalities. Some of the gene abnormalities found in PBL include: 1) increased expression of the "MYC" proto-oncogene due to its rearrangement with an antibody gene by genetic recombination or, less commonly, other causes (Myc protein, the product of this gene, enhances cell proliferation, inhibits apoptosis, and promotes malignancy); 2) loss in the expression of the "PRDM1" gene whose product, PRDM1/BLMP1 protein, represses the expression of Myc protein;) 3) frequent duplications in certain areas of chromosomes 1, 7, 11, and 22 (these duplications are similar to those often seen in diffuse large cell lymphoma); 4) reduced expression of at least 13 genes that are involved in B-cell responses to signaling agents. 5) increased expression of genes which promote the maturation of B-cells toward plasma cells (e.g. "CD38, CD138, IR4/MUM1, XBP1, IL21R", and, as just indicated, "PRDM1"); and 6) reduced expression of genes characteristic of B-cells (e.g. "CD20" and "PAX5").
https://en.wikipedia.org/wiki?curid=36982384
1,705,300
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An in-depth study of the brain of juvenile "Anteosaurus" specimen BP/1/7074 published in 2021 disproves the idea that this dinocephalian was a sluggish, crocodilian-like predator. Studies by Benoit "et al." using x-ray imaging and 3-D reconstructions showcase that "Anteosaurus" was a fast, agile animal in spite of its great size. Its inner ears were larger than those of its closest relatives and competitors, showcasing that it was well-suited to the role of an apex predator that could outrun both its rivals and prey alike. It was also determined that the area of the brain of "Anteosaurus" that was responsible for coordinating the movements of the eyes with the head was exceptionally large; an important feature in ensuring it could track its prey accurately. As a result, "Anteosaurus" was well-adapted to swift hunting and fast attacking strikes on land.
https://en.wikipedia.org/wiki?curid=6373564
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The "R. typhi" microorganism obligately resides within the epithelial cells of the midgut in flea hosts, and the endothelial cells lining the vasculature of mammalian species. The bacterium's lifecycle classically involves the Oriental rat flea ("Xenopsylla cheopis") and the black ("Rattus rattus") and brown ("Rattus norvegicus") rats. These globally distributed hosts are especially proficient at transmitting this rickettsiae for many reasons: "X. cheopis" has an incredibly wide host range and can thus transmit the bacterium to a broad set of mammalian hosts, including humans; members of the genus "Rattus" enable "R. typhi" to undergo massive rounds of binary fission within eukaryotic cells and increase the number of bacteria available to infect flea vectors. In addition to rats and their fleas, other hosts have been observed to naturally carry the microparasite as well, including cats and their fleas ("Ctenocephalides felis"), opossums, shrews, skunks, house mice and their fleas ("Leptopsylla segnis)," and rarely dogs. Cats and opossums are thought to be fairly significant reservoirs for murine typhus in urban environments due to their unpicky ectoparasites and close association with humans.
https://en.wikipedia.org/wiki?curid=20321247
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The challenge came from those dictators, first from Benito Mussolini, Duce of Italy, then from Adolf Hitler, Führer of a much more powerful Nazi Germany. The League of Nations proved disappointing to its supporters; it failed to resolve any of the threats posed by the dictators. British policy involved "appeasing" them in the hopes they would be satiated. By 1938 it was clear that war was looming, and that Germany had the world's most powerful military. The final act of appeasement came when Britain and France sacrificed Czechoslovakia to Hitler's demands at the Munich Agreement of September 1938. Instead of satiation, Hitler menaced Poland, and at last Prime Minister Neville Chamberlain dropped appeasement and stood firm in promising to defend Poland (31 March 1939). Hitler however cut a deal with Joseph Stalin to divide Eastern Europe (23 August 1939); when Germany did invade Poland in September 1939, Britain and France declared war, and the British Commonwealth followed London's lead.
https://en.wikipedia.org/wiki?curid=31731
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Liquid nitrogen (LN2) is a method of storing energy. Energy is used to liquefy air, and then LN2 is produced by evaporation, and distributed. LN2 is exposed to ambient heat in the car and the resulting nitrogen gas can be used to power a piston or turbine engine. The maximum amount of energy that can be extracted from LN2 is 213 Watt-hours per kg (W·h/kg) or 173 W·h per liter, in which a maximum of 70 W·h/kg can be utilized with an isothermal expansion process. Such a vehicle with a 350-liter (93 gallon) tank can achieve ranges similar to a gasoline powered vehicle with a 50-liter (13 gallon) tank. Theoretical future engines, using cascading topping cycles, can improve this to around 110 W·h/kg with a quasi-isothermal expansion process. The advantages are zero harmful emissions and superior energy densities compared to a compressed-air vehicle as well as being able to refill the tank in a matter of minutes.
https://en.wikipedia.org/wiki?curid=8340209
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In January 1933 Zander began development of the GIRD-X rocket (Note: "X" is the Roman numeral 10). It was originally to use a metallic propellant, but after various metals had been tested without success it was designed without a metallic propellant, and was powered by the Project 10 engine which was first bench tested in March 1933. This design burned liquid oxygen and gasoline and was one of the first engines to be regeneratively cooled by the liquid oxygen, which flowed around the inner wall of the combustion chamber before entering it. Problems with burn-through during testing prompted a switch from gasoline to less energetic alcohol. The final missile, long by in diameter, had a mass of , and it was anticipated that it could carry a payload to an altitude of . The GIRD X rocket was launched on 25 November 1933 and flew to a height of 80 meters.
https://en.wikipedia.org/wiki?curid=49664317
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Reverse ecology refers to the use of genomics to study ecology with no "a priori" assumptions about the organism(s) under consideration. The term was suggested in 2007 by Matthew Rockman during a conference on ecological genomics in Christchurch, New Zealand. Rockman was drawing an analogy to the term reverse genetics in which gene function is studied by comparing the phenotypic effects of different genetic sequences of that gene. Most researchers employing reverse ecology make use of some sort of population genomics methodology. This requires that a genome scan is performed on multiple individuals from at least two populations in order to identify genomic regions or sites that show signs of selection. These genome scans usually utilize single nucleotide polymorphism (SNP) markers, though use of microsatellites can work as well (with reduced resolution).
https://en.wikipedia.org/wiki?curid=32301719
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Construction depends on the material used. When steel or aluminium is used this involves welding of the plates and profiles after rolling, marking, cutting and bending as per the structural design drawings or models, followed by erection and launching. Other joining techniques are used for other materials like fibre reinforced plastic and glass-reinforced plastic. The process of construction is thought-out cautiously while considering all factors like safety, strength of structure, hydrodynamics, and ship arrangement. Each factor considered presents a new option for materials to consider as well as ship orientation. When the strength of the structure is considered the acts of ship collision are considered in the way that the ships structure is altered. Therefore, the properties of materials are considered carefully as applied material on the struck ship has elastic properties, the energy absorbed by the ship being struck is then deflected in the opposite direction, so both ships go through the process of rebounding to prevent further damage.
https://en.wikipedia.org/wiki?curid=76653
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The physical state (solid, liquid, or gas) of a reactant is also an important factor of the rate of change. When reactants are in the same phase, as in aqueous solution, thermal motion brings them into contact. However, when they are in separate phases, the reaction is limited to the interface between the reactants. Reaction can occur only at their area of contact; in the case of a liquid and a gas, at the surface of the liquid. Vigorous shaking and stirring may be needed to bring the reaction to completion. This means that the more finely divided a solid or liquid reactant the greater its surface area per unit volume and the more contact it with the other reactant, thus the faster the reaction. To make an analogy, for example, when one starts a fire, one uses wood chips and small branches — one does not start with large logs right away. In organic chemistry, on water reactions are the exception to the rule that homogeneous reactions take place faster than heterogeneous reactions ( are those reactions in which solute and solvent not mix properly)
https://en.wikipedia.org/wiki?curid=359135
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Per the regulations for the 2014 season, three practice sessions were held, two 90-minute sessions on Friday and another 60-minute session on Saturday. The first practice session was held under heavy cloud cover that threatened a heavy rain shower. Fernando Alonso of Ferrari was fastest with a benchmark lap of 1 minute and 17.238 seconds. He was ahead of the Mercedes duo of Hamilton and Rosberg. The Red Bull duo of Sebastian Vettel and Ricciardo were fourth and sixth; they were separated by Valtteri Bottas for Williams. Jenson Button, his McLaren teammate Kevin Magnussen, Ferrari driver Kimi Räikkönen and Toro Rosso's Jean-Éric Vergne rounded out the top ten fastest drivers. During the session, several drivers went off the circuit because of a low amount of grip and unable to get the optimum tyre temperature. Jules Bianchi damaged a right track rod on his Marussia from contact against a wall at turn four. Hülkenberg spun by putting his wheels in the grass at the turn eight chicane. Williams driver Felipe Massa stopped early with an ERS battery issue.
https://en.wikipedia.org/wiki?curid=38847346
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The first prototype, acting as an aerodynamic testbed only, flew on 21 October 1960. The first fully equipped aircraft followed it on 19 April 1961 and entered service with the US Navy as the E-2A in January 1964. By 1965, the project had accumulated so many development issues that it was cancelled after 59 aircraft had already been built. In particular, difficulties were being experienced due to inadequate cooling in the closely packed avionics compartment. Early computers and complex avionics systems generated considerable heat and could fail without proper ventilation. These issues continued long after the aircraft entered service. At one point, reliability was so bad that the entire fleet of aircraft was grounded.
https://en.wikipedia.org/wiki?curid=56075
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Social immune systems have been observed across a wide range of taxonomic groups. Allogrooming is found in many animals—for example primates frequently groom others, a behaviour which likely evolved for its hygienic function but has now been co-opted for its additional role in social bonding. Allogrooming in the common vampire bat ("Desmodus rotundus") is associated with the regurgitation of food and may allow other bats to identify which individuals are capable of supplying them with food; the allogrooming behaviours of horses and birds have also been studied. A range of sometimes elaborate cleaning symbioses also exist between many different species, especially in marine fish with their cleaning stations. Corsican blue tits ("Parus caeruleus") prophylactically line their nest with aromatic plants (such as "Achillea ligustica, Helichrysum italicum" and "Lavandula stoechas") to ward off mosquitoes and other blood-sucking ornithophillous (bird-targeting) insects.
https://en.wikipedia.org/wiki?curid=51046084
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Fungi typically enter the lung with inhalation of their spores, though they can reach the lung through the bloodstream if other parts of the body are infected. Also, fungal pneumonia can be caused by reactivation of a latent infection. Once inside the alveoli, fungi travel into the spaces between the cells and also between adjacent alveoli through connecting pores. This invasion triggers the immune system to respond by sending white blood cells responsible for attacking microorganisms (neutrophils) to the lungs. The neutrophils engulf and kill the offending organisms but also release cytokines which result in a general activation of the immune system. This results in the fever, chills, and fatigue common in bacterial and fungal pneumonia. The neutrophils and fluid leaked from surrounding blood vessels fill the alveoli and result in impaired oxygen transportation.
https://en.wikipedia.org/wiki?curid=2441429
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As to why plants synthesize tocochromanols, the major reason appears to be for antioxidant activity. Different parts of plants, and different species, are dominated by different tocochromanols. The predominant form in leaves, and hence leafy green vegetables is α-tocopherol. Location is in chloroplast membranes, in close proximity to the photosynthetic process. The function is to protect against damage from the ultraviolet radiation of sunlight. Under normal growing conditions the presence of α-tocopherol does not appear to be essential, as there are other photo-protective compounds, and plants that through mutations have lost the ability to synthesize α-tocopherol demonstrate normal growth. However, under stressed growing conditions such as drought, elevated temperature or salt-induced oxidative stress, the plants' physiological status is superior if it has the normal synthesis capacity.
https://en.wikipedia.org/wiki?curid=54104
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Subresolution assist features (SRAFs) are features which are separated from targeted features but assist in their printing, while not being printed themselves. Printing SRAFs are a critical yield detractor and require additional OPC models to determine and remove SRAFs where undesirable printing may occur. SRAFs have more pronounced effects on the diffraction spectrum than targeted feature resizing and/or attachments. The requirement to not print constrains their use with low doses only. This could pose issues with stochastic effects. Hence their main application is to improve depth of focus for isolated features (dense features do not leave enough room for SRAF placement). Since SRAFs redistribute energy toward higher spatial frequencies or diffraction orders, the depth of focus is more dependent on the illumination angle (center of spectrum of spatial frequencies or diffraction orders) as well as the pitch (separation of spatial frequences or diffraction orders). In particular, different SRAFs (position, shape, size) could result in different illumination specifications. In fact, certain pitches forbid the use of SRAFs for specific illumination angles. Since the pitch is usually predetermined, some illumination angles must be avoided even with the use of SRAF OPC. Generally, though, SRAFs cannot be a complete solution, and can only approach the dense case, not match it.
https://en.wikipedia.org/wiki?curid=3263872
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According to Brigadier General Murad Turaiq, the commander of some of the Yemeni forces allied to the Saudi-led coalition currently fighting in Yemen, Patriot air defense systems deployed to Yemen by the United Arab Emirates (UAE) have successfully intercepted two ballistic missiles fired by Houthi forces. General Turaiq told the Abu Dhabi-based "The National" newspaper on November 14 that the first missile was shot down late the previous day in the Al-Gofainah area and a second was intercepted before it hit the building hosting the control centre for forces operating in Marib and Al-Baydah provinces. Airbus Defence and Space satellite imagery obtained by IHS Jane's showed two Patriot fire units, each with just two launchers, deployed at the Safir airstrip in Marib province on October 1.
https://en.wikipedia.org/wiki?curid=52024
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The GC-EI-MS is also used in forensic science. One example is the analysis of five local anesthetics in blood using headspace solid-phase microextraction (HS-SPME) and gas chromatography–mass spectrometry–electron impact ionization selected ion monitoring (GC–MS–EI-SIM). Local anesthesia is widely used but sometimes these drugs can cause medical accidents. In such cases an accurate, simple, and rapid method for the analysis of local anesthetics is required. GC-EI-MS was used in one case with an analysis time of 65 minutes and a sample size of approximately 0.2 g, a relatively small amount. Another application in forensic practice is the determination of date rape drugs (DRDs) in urine. These drugs are used to incapacitate victims and then rape or rob them. The analyses of these drugs are difficult due to the low concentrations in the body fluids and often a long time delay between the event and clinical examination. However, using GC-EI-MS allows a simple, sensitive and robust method for the identification, detection and quantification of 128 compounds of DRDs in urine.
https://en.wikipedia.org/wiki?curid=340284
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Jenson Button made his Formula One debut in 2000 at the age of 20, making him the youngest British driver to compete in the sport until Lando Norris made his debut in the 2019 F1 season. He started his career with Williams, scoring a point in his second race. He would later race for British American Racing, a team that would then be purchased by Honda with whom he would win his first race, the 2006 Hungarian Grand Prix. Following the 2008 season, Honda decided to withdraw from F1, and the team was saved by a management buyout. The team returned as Brawn GP and saw immediate success. Button went on to achieve his most significant F1 successes, winning six of the first seven races in 2009 on the way to the world title. In 2010, he moved to McLaren, for whom he raced until the end of his career. He retired at the end of the 2016 season but raced in the 2017 Monaco Grand Prix as a replacement driver.
https://en.wikipedia.org/wiki?curid=36898734
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TFTR won the construction race and began operation in 1982, followed shortly by JET in 1983 and JT-60 in 1985. JET quickly took the lead in critical experiments, moving from test gases to deuterium and increasingly powerful "shots". But it soon became clear that none of the new systems were working as expected. A host of new instabilities appeared, along with a number of more practical problems that continued to interfere with their performance. On top of this, dangerous "excursions" of the plasma hitting with the walls of the reactor were evident in both TFTR and JET. Even when working perfectly, plasma confinement at fusion temperatures, the so-called "fusion triple product", continued to be far below what would be needed for a practical reactor design.
https://en.wikipedia.org/wiki?curid=31439
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Initially his research was in the field of polymer chemistry and polymer reaction kinetics. His research has expanded towards the fusion of polymer chemistry with organic and photochemistry. Current research areas include the development of advanced wavelength-orthogonal reactions and their photophysical understanding, most notably opening the field of action spectra for photochemical covalent bond formation and cleavage, translated to the photochemical synthesis of highly defined macromolecular architectures. The developed photochemical platform finds application for the design of 2D and 3D photolithographic processes as well as in biosystems including single cell scaffolds. Christopher Barner-Kowollik has published over 700 peer-reviewed research papers which have been cited close to 40,000 times.
https://en.wikipedia.org/wiki?curid=57789931
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The first iron lung used in the treatment of polio was invented by Philip Drinker, Louis Agassiz Shaw, and James Wilson at Harvard, and tested October 12, 1928, at Children's Hospital, Boston. The original Drinker iron lung was powered by an electric motor attached to two vacuum cleaners, and worked by changing the pressure inside the machine. When the pressure is lowered, the chest cavity expands, trying to fill this partial vacuum. When the pressure is raised the chest cavity contracts. This expansion and contraction mimics the physiology of normal breathing. The design of the iron lung was subsequently improved by using a bellows attached directly to the machine, and John Haven Emerson modified the design to make production less expensive. The Emerson Iron Lung was produced until 1970. Other respiratory aids were used, such as the Bragg-Paul Pulsator and the "rocking bed" for patients with less critical breathing difficulties.
https://en.wikipedia.org/wiki?curid=11110672
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The concentration of galectin-3 is elevated in the circulation of patients with some types of cancer including breast cancer. It has also been identified bound to glycans on the surface of breast cancer cells. In cancer patients whose cancer has metastasised, galectin-3 is higher still, suggesting that this galectin has a crucial role in metastasis. Galectin-3 also binds to MUC-1, a very large transmembrane mucin, which on cancer cells changes expression from long core 2 type O-glycosylation to shorter core 1 type O-glycosylation. Core 2 glycans terminate in galactose or sialic acid, whereas core 1 is branched and has potential for large carbohydrate extensions. High levels of MUC-1 are associated with poor prognosis and increased potential of metastasis. This cancer-associated MUC-1 is a natural ligand for galectin-3. In normal cells, MUC-1 has distinct polarisation and acts as a protective barrier around the cell, reducing cell-cell interactions. In breast cancer cells, it is hypothesised that galectin-3 has high affinity for cancer-associated MUC-1, causing depolarisation and breaking the cell's protective shield. This exposes small adhesion molecules on the surface of the cell, which interact with adhesion proteins on endothelial cell walls, such as E-selectin, promoting intravastion into the blood stream. Experiments shows that overexpression of MUC-1 alone is not enough to increase metastatic potential, and in fact it inhibits tumour cell entry into the blood stream. It requires the presence of upregulated galectin-3 in addition to MUC-1 to increase invasive and metastatic properties of the cancer. This is supported by other studies showing that inhibition of galectin-3 in human breast cancer cells lose their malignancy in vitro. This may provide a clue towards developing therapeutics for cancer, such as galectin-3 inhibitors.
https://en.wikipedia.org/wiki?curid=9691122
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TRP channels modulate ion entry driving forces and Ca and Mg transport machinery in the plasma membrane, where most of them are located. TRPs have important interactions with other proteins and often form signaling complexes, the exact pathways of which are unknown. TRP channels were initially discovered in the "trp" mutant strain of the fruit fly "Drosophila" which displayed transient elevation of potential in response to light stimuli and were so named "transient receptor potential" channels. TRPML channels function as intracellular calcium release channels and thus serve an important role in organelle regulation. Importantly, many of these channels mediate a variety of sensations like the sensations of pain, temperature, different kinds of tastes, pressure, and vision. In the body, some TRP channels are thought to behave like microscopic thermometers and are used in animals to sense hot or cold. TRPs act as sensors of osmotic pressure, volume, stretch, and vibration. TRPs have been seen to have complex multidimensional roles in sensory signaling. Many TRPs function as intracellular calcium release channels.
https://en.wikipedia.org/wiki?curid=1033847
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In marine and freshwater ecology, a particle is a small object. Particles can remain in suspension in the ocean or freshwater. However, they eventually settle (rate determined by Stokes' law) and accumulate as sediment. Some can enter the atmosphere through wave action where they can act as cloud condensation nuclei (CCN). Many organisms filter particles out of the water with unique filtration mechanisms (filter feeders). Particles are often associated with high loads of toxins which attach to the surface. As these toxins are passed up the food chain they accumulate in fatty tissue and become increasingly concentrated in predators (see bioaccumulation). Very little is known about the dynamics of particles, especially when they are re-suspended by dredging. They can remain floating in the water and drift over long distances. The decomposition of some particles by bacteria consumes much oxygen and can cause the water to become hypoxic.
https://en.wikipedia.org/wiki?curid=1109435
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Advanced Patent made its move into the gaming industry in 1979, acquiring United Coin Machine Company, one of the largest slot route operators in Nevada, and announcing plans for the Colorado Belle hotel and casino in Laughlin, the first of a series of hotels to be built in the Las Vegas area. An obstacle arose in July 1980 in the form of an SEC investigation, alleging inadequate financial disclosure and sale of unregistered stock. Under scrutiny from the Nevada Gaming Commission, Solomon was forced to step down as chairman, as a condition of licensing for the casino. Three new directors were added in November to the company's board as part of a settlement under discussion with the SEC, but by March 1981, regulators still had questions about the company's public disclosure, and trading in the stock was suspended for 10 days. The SEC investigation ended in 1983 with no further action against the company, while Solomon personally agreed to an injunction against any further securities violations, rather than fighting charges that he illegally sold stock in the company between 1975 and 1980 to raise money for its gaming ventures.
https://en.wikipedia.org/wiki?curid=767523
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However it is possible to talk about a modulation index exceeding 100%, without introducing distortion, in the case of double-sideband reduced-carrier transmission. In that case, negative excursions beyond zero entail a reversal of the carrier phase, as shown in the third waveform below. This cannot be produced using the efficient high-level (output stage) modulation techniques (see below) which are widely used especially in high power broadcast transmitters. Rather, a special modulator produces such a waveform at a low level followed by a linear amplifier. What's more, a standard AM receiver using an envelope detector is incapable of properly demodulating such a signal. Rather, synchronous detection is required. Thus double-sideband transmission is generally "not" referred to as "AM" even though it generates an identical RF waveform as standard AM as long as the modulation index is below 100%. Such systems more often attempt a radical reduction of the carrier level compared to the sidebands (where the useful information is present) to the point of double-sideband suppressed-carrier transmission where the carrier is (ideally) reduced to zero. In all such cases the term "modulation index" loses its value as it refers to the ratio of the modulation amplitude to a rather small (or zero) remaining carrier amplitude.
https://en.wikipedia.org/wiki?curid=1140
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Chemical digestion follows a number of steps. Initially the only chemical treatment used by researchers was treatment with Potassium hydroxide (KOH) to remove humic substances; defloculation was accomplished through surface treatment or ultra-sonic treatment, although sonification may cause the pollen exine to rupture. In 1924, the use of hydrofluoric acid (HF) to digest silicate minerals was introduced by Assarson and Granlund, greatly reducing the amount of time required to scan slides for palynomorphs. Palynological studies using peats presented a particular challenge because of the presence of well-preserved organic material, including fine rootlets, moss leaflets and organic litter. This was the last major challenge in the chemical preparation of materials for palynological study. Acetolysis was developed by Gunnar Erdtman and his brother to remove these fine cellulose materials by dissolving them. In acetolysis the specimen is treated with acetic anhydride and sulfuric acid, dissolving cellulistic materials and thus providing better visibility for palynomorphs.
https://en.wikipedia.org/wiki?curid=328274
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In the spring of 1975, Fred Silverman became the first president and director of programming of ABC Entertainment, the independent television production subsidiary created from the network's namesake programming division. In 1974, ABC premiered the police series "S.W.A.T.". That same year, the network decided to compete with NBC's morning news-talk program "Today". Its first attempt was "AM America"; however, that show's success was not straightforward. Boston affiliate WCVB-TV produced morning show "Good Day!" (initially premiering as "Good Morning!" in 1973) which was groundbreaking for being entirely produced and broadcast from road locations, while Cleveland affiliate WEWS-TV was producing "The Morning Exchange" since 1972 and which in summer 1975 was locally pre-empting "AM America"; this was the first-morning show to use a set modeled after a living room and provided news and weather updates at the top and bottom of each hour. Discovering that these formats appealed to viewers, the network adopted them for a new national morning show, "Good Morning America", which debuted on November 3, 1975. In 1975, ABC launched the short-lived late night comedy show "Saturday Night Live with Howard Cosell". The show was not a tremendous success and was cancelled shortly afterward. After the program's cancellation, NBC purchased the rights to the title and rechristened its own comedy sketch show from "NBC's Saturday Night" to "Saturday Night Live".
https://en.wikipedia.org/wiki?curid=64765894
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Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. This bacterium is a facultative anaerobic organism that is catalase-positive and capable of beta-hemolysis. In small ruminants, "C. pseudotuberculosis" causes a disease called caseous lymphadenitis characterized by pyogranulomatous abscess formation. In general, this bacterium causes lesions of the skin, lymph nodes, and internal organs. A disease known as ulcerative lymphagenitis can also result from infection with "C. pseudotuberculosis" in the distal limbs of horses. This bacterium uses the virulence factors phospholipase D and mycolic acid to damage eukaryotic cell walls and resist phagocytic lysosomal degradation, respectively. Infection with this bacterium is often confirmed by bacterial culture of the purulent exudate. Once the diagnosis has been made, treatment of the infection can begin, but this is difficult due to the nature of the organism and the lesions it forms. Specifically, "C. pseudotuberculosis" is intrinsically resistant to streptomycin, with varying resistance to penicillin and neomycin depending on the strain. It has been shown to be susceptible to ampicillin, gentamicin, tetracycline, lincomycin, and chloramphenicol. Vaccines have also been produced to develop acquired immunity to this infection.
https://en.wikipedia.org/wiki?curid=65001349
1,721,362
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Arthur Evans, the first archaeologist to excavate Minoan Knossos, hired the Swiss artist Emile Gilliéron and his son, Emile, as the chief fresco restorers at Knossos. The restorations have been often criticised subsequently; and are now viewed with a "healthy skepticism" as "overconfident" by specialists. In one important case a figure of a monkey was turned into a boy; in fact human figures do not usually appear in "landscape" fresco scenes. Spyridon Marinatos unearthed the ancient site at Akrotiri, then capital of Santorini, which included the Wall Paintings of Thera, frescoes which make it the second-most famous Minoan site. Although the paintings are rather less refined, and its political relationship with Crete is uncertain, the town was covered in volcanic ash in the Minoan eruption around 1600 BC, and many of them have survived far more completely than those from Crete. Unusually, they include life-size female figures, one apparently a priestess.
https://en.wikipedia.org/wiki?curid=20435731
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The M728 has been determined by the US Army to be inadequate to fully support the M1 Abrams and M2 Bradley vehicles, also cited were the rising costs to maintain and difficulty in acquiring parts for a low density piece of equipment and was retired from combat use with no clear replacement in 2000. In the late 1990s, the Army decided it could not afford to continue developing complicated, maintenance-heavy vehicles for this purpose. The M1 Grizzly Combat Mobility Vehicle (CMV) was canceled in 2001, and the prototype developed never went into full production. The Marine Corps however persisted and funded its own development and testing of the M1150 Assault Breacher Vehicle. As of 2009 it is still used by the Army National Guard and US Army Reserve. In 2018 the US Army began to phase out the M728 from service with the Army Reserves and National Guard replacing them with the M1150 and is to be completely withdrawn from US service by 2024.
https://en.wikipedia.org/wiki?curid=559429
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Compared to other aquaculture technology, IFCAS showed several benefits to the adopting farmers. Like traditional aquaponics, fish and plants also rely on each other in aquageoponics. Here a mutual relationship exists between fish and plants. Unused fish feed and excrements result in nitrogenous wastes in the pond water and mud what are used as nutrients (nitrate) by the plants in IFCAS. Here some substrates such as, fallen leaves from horticulture plants, mud and materials in IFCAS (such as drums, iron plates etc.) harbour the nitrifying bacteria what convert toxic ammonia to less harmful nitrate. Plant roots hanging from IFCAS pits, absorb nutrients more effectively from water than plants do in traditional soil based agriculture as roots are longer and healthier in IFCAS. Like in aquaponics, plants grow faster in IFCAS also. Moreover, symbiotically plants facilitate by providing fish with ammonia free water in return. Harvesting fish and vegetables from IFCAS is very easy for both men and women. Apart from consumption of fish and vegetables at the household level, farmers earned money by selling fish from IFCAS. IFCAS is not only useful in the small shaded ponds but also in multi-ownership ponds, state-owned ponds, natural water bodies (beel), rivers, canals, and the waterlogged areas affected by climate change. Along with dissemination of this technology in Bangladesh, IFCAS has been trialed in ponds in Nepal which was found encouraging for nursing fish fingerlings and vegetables during dry season.
https://en.wikipedia.org/wiki?curid=43834932
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The MIC belongs to the maximal information-based nonparametric exploration (MINE) class of statistics. In a simulation study, MIC outperformed some selected low power tests, however concerns have been raised regarding reduced statistical power in detecting some associations in settings with low sample size when compared to powerful methods such as distance correlation and Heller–Heller–Gorfine (HHG). Comparisons with these methods, in which MIC was outperformed, were made in Simon and Tibshirani and in Gorfine, Heller, and Heller. It is claimed that MIC approximately satisfies a property called "equitability" which is illustrated by selected simulation studies. It was later proved that no non-trivial coefficient can exactly satisfy the "equitability" property as defined by Reshef et al., although this result has been challenged. Some criticisms of MIC are addressed by Reshef et al. in further studies published on arXiv.
https://en.wikipedia.org/wiki?curid=34115448
1,255,859
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In 1842, the bishop of Vincennes, Célestin Guynemer de la Hailandière, offered land to Edward Sorin of the Congregation of Holy Cross, on the condition that he build a college in two years. Stephen Badin, the first priest ordained in the United States, who had come to the area invited by Potawatomi chief Leopold Pokagon to minister to his tribe, had bought these of land in 1830. Sorin arrived on the site with eight Holy Cross brothers from France and Ireland on November 26, 1842, and began the school using Badin's old log chapel. After enrolling two students, Sorin soon erected more buildings, including the Old College, the first church, and the first main building. Notre Dame began as a primary and secondary school; in 1844 it received its official college charter from the Indiana General Assembly, under the name the University of Notre Dame du Lac (University of Our Lady of the Lake). Because the university was originally all-male, the Sisters of the Holy Cross founded the female-only Saint Mary's College near Notre Dame in 1844.
https://en.wikipedia.org/wiki?curid=146269
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The P-59A had an oval cross-section, all-metal stressed skin semi-monocoque fuselage that housed a single pressurized cockpit. The mid-mounted, straight wing had two spars plus a false spar in the inner panel. The electrically-powered tricycle landing gear was attached to the center spar. The pair of General Electric J31 turbojets were positioned under the wing roots in streamlined nacelles. The armament was located in the nose of the aircraft; two of the three XP-59As and most of the YP-59As had a pair of M10 autocannon. Later aircraft, including the production models, had one M10 autocannon and three AN/M2 Browning heavy machine guns. The aircraft carried a total of of fuel in four self-sealing tanks in the inner wing panels. Both production models could carry drop tanks under the wings. In addition, the P-59B was provided with a fuel tank in each outer wing panel.
https://en.wikipedia.org/wiki?curid=364859
948,779
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Modern complex AI techniques, such as deep learning and genetic algorithms are naturally opaque. To address this issue, there has been a development of many new methods to make new models more explainable and interpretable. This includes many methods, such as Layerwise relevance propagation (LRP), a technique for determining which features in a particular input vector contribute most strongly to a neural network's output. Other techniques have been developed to explain one particular prediction made by a (nonlinear) black-box model, a goal referred to as "local interpretability". It is worth noting that the mere transposition of the concepts of local interpretability into a remote context (where the black-box model is executed at a third party) is currently under scrutiny.
https://en.wikipedia.org/wiki?curid=54575571
978,192
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These two components, used together, allow a much finer degree of substance identification than either unit used separately. It is not possible to make an accurate identification of a particular molecule by gas chromatography or mass spectrometry alone. The mass spectrometry process normally requires a very pure sample while gas chromatography using a traditional detector (e.g. Flame ionization detector) cannot differentiate between multiple molecules that happen to take the same amount of time to travel through the column ("i.e." have the same retention time), which results in two or more molecules that co-elute. Sometimes two different molecules can also have a similar pattern of ionized fragments in a mass spectrometer (mass spectrum). Combining the two processes reduces the possibility of error, as it is extremely unlikely that two different molecules will behave in the same way in both a gas chromatograph and a mass spectrometer. Therefore, when an identifying mass spectrum appears at a characteristic retention time in a GC-MS analysis, it typically increases certainty that the analyte of interest is in the sample.
https://en.wikipedia.org/wiki?curid=846892
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By contrast Marx and Engels were extremely wary of the role of what may be described as 'professional theoreticians', however learned, who were only tenuously familiar with their theory and not tied to the struggles of the working class. Thus we find Marx writing to Sorge in October 1877, following the fusion of the German Social Democrats with the Lassalleans, complaining about the reintroduction of utopian socialism into the movement ("which for tens of years we have been clearing out of the German workers’ heads with so much toil and labour") by "a whole gang of half-mature students and super-wise doctors who want to give socialism a “higher ideal” orientation, that is to say, to replace its materialistic basis (which demands serious objective study from anyone who tries to use it) by modern mythology with its goddesses of Justice, Freedom, Equality and Fraternity." As their influence persisted, Engels remarked in a similar vein:
https://en.wikipedia.org/wiki?curid=39606912
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Sauveur is known principally for his detailed studies on acoustics. Indeed, he has been credited with coining the term "acoustique", which he derived from the ancient Greek word ακουστός, meaning "able to be heard". His work involved researching the correlation between frequency and musical pitch, and – putting Fontenelle's statements in modern terms – he conducted studies on subjects such as the vibrating string, tuning pitch, harmonics, ranges of voices and musical instruments, et al. He also created a measure of intervals concerning the octave. Though Marin Mersenne's 1637 theories are correct, his measurements are not very exact, and his calculation of Mersenne's laws was greatly improved by Sauveur through the use of acoustic beats and metronomes. The following are some of the terms Sauveur used as logarithmic divisions:
https://en.wikipedia.org/wiki?curid=8676042
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Most research to date use common rodent models to investigate the role of nutrition on phenotype. Popular areas to investigate include IUGR studies, whereby rodents, and sometimes sheep, are subjected to a variety of nutritional conditions. A model for studying IUGR in rodent was developed by Simmons "et al." (2010) and is used to investigate type II diabetes. The maternal rats have their uterine arteries ligated, causing altered use of glucose and insulin in the fetus and can therefore serve as a model for diabetes. These growth-retarded rats were found to be highly similar to human fetuses, as they both display symptoms such as lowered glucose and insulin levels. Gestational diabetes may also be studied through chemical induction using streptozotocin treatment of the pregnant rats. Streptozotocin can cause destruction of the beta cells within the pancreas depending on the concentration given.
https://en.wikipedia.org/wiki?curid=30932051
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The Protocetidae, known from both Africa and America, were a diversified family with hind limbs and a strong tail, indicating that they were strong swimmers that colonized shallow and warm oceans, such as reefs. They greatly affected cetacean evolution , because they spread across Earth's oceans. They had long snouts, large eyes, and a nasal opening located farther up the head than in earlier archaeocetes — suggesting they could breathe with the head held horizontally, similar to modern cetaceans — a first step towards a blowhole. Their dentition varied, but started to evolve towards the nonmasticating teeth of modern cetaceans, and they were probably active hunters. Their ability to move on land seems to have been variable: in "Rodhocetus" and "Peregocetus" possess a sacroiliac joint, indicating they could move on land. In other genera ("Georgiacetus" and "Aegicetus"), the pelvis was not connected to the vertebral column, suggesting the hind limbs could not have supported the body weight. Some genera ("Rodhocetus") had large hind feet forming large paddles, while "Aegicetus" seems to have relied more on its tail to propel itself through the water.
https://en.wikipedia.org/wiki?curid=5234427
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Prasad returned to India in 1947 and joined Patna Medical College and Hospital in 1948 as a lecturer at the department of medicine and became a professor in 1962. During his tenure there, he started the department of pediatrics and, later, developed the children's ward into a hospital with a capacity of 250 beds. He also served the Rajendra Memorial Research Institute of Medical Sciences, Patna as an honorary director. In the early sixties, Prasad joined with George Coelho and his associate pediatrics to merge the Association of Pediatricians of India and the Indian Pediatric Society under one umbrella with a new identity in 1964 and Prasad was made the founder president of the new organization, the Indian Academy of Pediatrics. He took superannuation from Patna Medical College on 31 December 1971 but continued his activities by associating himself with the various medical committees.
https://en.wikipedia.org/wiki?curid=46915854
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To achieve sustainable interoperability in the Internet of things ecosystem, two dominant architectures for data exchange protocols are used: bus-based (DDS, REST, XMPP) and broker-based (AMQP, CoAP, MQTT, JMI). Protocols that support information exchange between interoperable domains are classified as message-centric (AMQP, MQTT, JMS, REST) or data-centric (DDS, CoAP, XMPP). Interconnected devices communicate using lightweight protocols that don't require extensive CPU resources. C, Java, Python and some scripting languages are the preferred choices of IoT application developers. IoT nodes use separate IoT gateways to handle protocol conversion, database storage or decision making (e.g. collision handling), in order to supplement the low intelligence of devices.
https://en.wikipedia.org/wiki?curid=1338556
754,327
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In January 2018, the NYCT and Bus Committee recommended that Judlau Contracting receive the $125 million contract for Package 4 and that Citnalta-Forte receive the $125 million contract for Package 8. However, the MTA Board temporarily deferred the vote for these packages after city representatives refused to vote to award the contracts, citing the high cost and relatively low importance of the program. Some executives had pointed out that improving subway service was more important than renovating stations that were used by relatively few people. In response, MTA Chairman Joe Lhota said that these stations had been selected because ESI was a "pilot" program, and thus, the renovations would be tested on smaller stations first. NYCT Chairman Andy Byford looked over the list of ESI stations and concluded that the list was suitable because these stations were in need of structural improvements. He said that the MTA's decision to not add elevators was reasonable because the work involved would have delayed many of the projects for several years, and in some cases, other nearby stops already had or were getting elevators. The ESI packages were put back for a vote in February, and the two contracts were ultimately approved, with three city representatives dissenting.
https://en.wikipedia.org/wiki?curid=55208663
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Large sections of the AW139 have been developed and produced by a range of different companies. Airframes are typically produced by PZL-Świdnik, who delivered their 200th airframe in April 2014. Pratt & Whitney Canada produce the type's PT6C turboshaft engines, while the primary and secondary transmissions were developed by Westland GKN and Kawasaki Heavy Industries respectively. A significant portion of the avionics are sourced from Honeywell. Turkish Aerospace Industries has been subcontracted to manufacture various elements of the AW139, including the fuselage, canopy, and radome. Final assembly of most AW139s is performed at AgustaWestland's facilities in Philadelphia, United States, and Vergiate, Italy; those destined for customers within the Commonwealth of Independent States are typically assembled by a third final manufacturing plant in Tomilino, Moscow operated by HeliVert.
https://en.wikipedia.org/wiki?curid=6378164
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Immediate support was offered by the Royal Navy, Japan Maritime Self-Defense Force and the United States Navy. The United Kingdom sent a Scorpio 45 ROV via C-17 Globemaster III cargo aircraft and a team to operate it. The United States sent one unmanned Super Scorpio ROV from San Diego, airlifted via C-5 Galaxy transport. Each unmanned vehicle was also accompanied by a team to operate it. It was intended that these unmanned rescue vessels, with their robotic arms, would be able to cut the nets or cables that anchored the submarine. The American ROV was assembled on the Priz support ship although they were not required to get underway as the British Scorpio was able to execute the rescue. A tactical decision by the PACFLT command team in Pearl Harbor, allowed the British crew to use the limited local resources toward one rescue asset. The British team's efforts resulted in a successful rescue.
https://en.wikipedia.org/wiki?curid=2384834
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In 2010 David Hone with team reported a new interaction between "Velociraptor" and "Protoceratops" based on tooth marks. Several fossils were collected at the Gate locality of the Bayan Mandahu Formation in 2008, including teeth and body remains of protoceratopsid and velociraptorine dinosaurs. The team referred these elements to "Protoceratops" and "Velociraptor" mainly based on their abundance across the unit, although they admitted that reported remains could represent different, yet related taxa (in this case, "Linheraptor" instead of "Velociraptor"). At least 8 body fossils of "Protoceratops" present active teeth marks, which were interpreted as feeding traces. Much in contrast to the Fighting Dinosaurs specimen, the tooth marks are inferred to have been produced by the dromaeosaurid during late-stage carcass consumption either during scavenging or following a group kill. The team stated that feeding by "Velociraptor" upon "Protoceratops" was probably a relatively common occurrence in these environments, and that this ceratopsian actively formed part of the diet of "Velociraptor".
https://en.wikipedia.org/wiki?curid=1064031
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Military degrees were considered inferior to civil degrees and did not carry the same prestige. The names of civil "jinshi" were carved in marble whereas military "jinshi" were not. While the military and civil services were imagined in Chinese political philosophy as the two wheels of a chariot, in practice, the military examination degree was highly regarded by neither the army or the world at large. Soldiers preferred not having military exam graduates as commanders whose skills in test taking did not necessarily transfer to the army. Final decision for appointment in the military still came down to forces outside the examination system. For example, at the beginning of 755, An Lushan replaced 32 Han Chinese commanders with his own barbarian favorites without any repercussions. During the Qing dynasty, the pre-existing institutions of the Eight Banners and Green Standard Army had their own rules for promotion and left little room for military exam graduates. Some of the few military examination graduates who did achieve distinction include the Tang general Guo Ziyi, the father of the founder of the Song dynasty Zhao Hongyin, Ming generals Yu Dayou and Qi Jiguang, and Ming general turned traitor Wu Sangui. However these are but a minuscule number among those who passed the 282 military metropolitan exams held between their inception in 702 and abolishment in 1901. Even in desperate times of war, the majority of distinguished military figures in Chinese history have come from civil degree holders. The practices of the Ming and Qing military exams were incorporated into physical education in the Republic of China.
https://en.wikipedia.org/wiki?curid=244479
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Cuvier's beaked whales ("Ziphius cavirostrus") are an open-ocean species that rarely approach the shore, making them difficult to study in the wild. Prior to the interest raised by the sonar controversy, most of the information about them came from stranded animals. The first to publish research linking beachings with naval activity were Simmonds and Lopez-Jurado in 1991. They noted that over the past decade there had been a number of mass strandings of beaked whales in the Canary Islands, and each time the Spanish Navy was conducting exercises. Conversely, there were no mass strandings at other times. They did not propose a theory for the strandings. Fernández "et al." in a 2013 letter to "Nature", reported that there had been no further mass strandings in that area, following a 2004 ban by the Spanish government on military exercises in that region.
https://en.wikipedia.org/wiki?curid=851060
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Generally the production of neutrons at a spallation source begins with a high-powered proton accelerator. The accelerator may consist of a linac only (as in the European Spallation Source) or a combination of linac and synchrotron (e.g. ISIS neutron source) or a cyclotron (e.g. SINQ (PSI)) . As an example, the ISIS neutron source is based on some components of the former Nimrod synchrotron. Nimrod was uncompetitive for particle physics so it was replaced with a new synchrotron, initially using the original injectors, but which produces a highly intense pulsed beam of protons. Whereas Nimrod would produce around 2 µA at 7 GeV, ISIS produces 200 µA at 0.8 GeV. This is pulsed at the rate of 50 Hz, and this intense beam of protons is focused onto a target. Experiments have been done with depleted uranium targets but although these produce the most intense neutron beams, they also have the shortest lives. Generally, therefore, tantalum or tungsten targets have been used. Spallation processes in the target produce the neutrons, initially at very high energies—a good fraction of the proton energy. These neutrons are then slowed in moderators filled with liquid hydrogen or liquid methane to the energies that are needed for the scattering instruments. Whilst protons can be focused since they have charge, chargeless neutrons cannot be, so in this arrangement the instruments are arranged around the moderators.
https://en.wikipedia.org/wiki?curid=1220790
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OPEs have a central phosphate molecular group. In the case of organophosphate (OP) triesters, these are three ester bonds with alkyl or aromatic substituents. However, OP diesters are distinct from the triesters as one of the alkyl ester groups is replaced by a hydroxyl group, making OP diesters phosphoric acids. The wide variety of substitutes used in organophosphate esters results in great variations in physicochemical properties, varying from highly polar to very hydrolysis resistant characteristics. OPEs exhibit a wide range of octanol water partitioning coefficient where log Kow values range from -0.98 up to 10.6. The predominant OPEs used as flame retardants and plasticizers have a positive log Kow values ranging between 1.44 and 9.49 signifying hydrophobicity. Thus, owing to this hydrophobicity OPEs are presumptively bioaccumulated and biomagnified in aquatic ecosystems. Laboratory experiments had shown that the non-halogenated OPEs are prone to photolysis, while the chlorinated OPEs such as TCEP and TCPP, however, seemed to be resistant to degradation by sunlight.
https://en.wikipedia.org/wiki?curid=959629
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At the beginning, none of the favorites wanted to lead the race, so leading duties fell on Alina Reh to keep the pace honest, 9:29.69 for the 3000 metres. A lap later, #3 Kenyan Rosemary Wanjiru accelerated. The field strung out. Her teammates Hellen Obiri and Agnes Tirop followed. If it was a sacrificial tactic, the Ethiopian team took the bait. Letesenbet Gidey, Netsanet Gudeta and Senbere Teferi came forward in chase of the breakaway. The only other athlete to join the lead group was Sifan Hassan, who took a little more than a lap to bridge the gap from the back of the pack. The Kenyan team shared the leading duties, pushing the pace down to 15:32:70. Gudeta couldn't keep up with the fast pace, eventually dropping out. The Kenyan efforts kept driving the train until 4 laps to go when World leader Gidey quickly accelerated to the lead. The Kenyans struggled to keep up, again late to bridge the gap, Hassan went around the Kenyan team to catch Gidey just before the bell. Running around lapped runners, Hassan extended the gap to win by 3.5 seconds in 30:17.62. Tirop held on for bronze.
https://en.wikipedia.org/wiki?curid=61899751
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Electron-transfer dissociation (ETD) is a method of fragmenting multiply-charged gaseous macromolecules in a mass spectrometer between the stages of tandem mass spectrometry (MS/MS). Similar to electron-capture dissociation, ETD induces fragmentation of large, multiply-charged cations by transferring electrons to them. ETD is used extensively with polymers and biological molecules such as proteins and peptides for sequence analysis. Transferring an electron causes peptide backbone cleavage into c- and z-ions while leaving labile post translational modifications (PTM) intact. The technique only works well for higher charge state peptide or polymer ions (z>2). However, relative to collision-induced dissociation (CID), ETD is advantageous for the fragmentation of longer peptides or even entire proteins. This makes the technique important for top-down proteomics. The method was developed by Hunt and coworkers at the University of Virginia.
https://en.wikipedia.org/wiki?curid=11087461
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The lower end E6300 (1.86 GHz) and E6400 (2.13 GHz), both with a 1066 MHz FSB (64-bits wide), were released on July 27, 2006. Traditionally, CPUs of the same family with less cache simply have the unavailable cache disabled, since this allows parts that fail quality control to be sold at a lower rating. When yields improve, they may be replaced with versions that only have the cache amount needed on the die, to bring down manufacturing cost. At launch time, Intel's prices for the Core 2 Duo E6300 and E6400 processors were US$183 and US$224 each in quantities of 1000. Conroe CPUs have improved capabilities over previous models with similar processor clock rates. According to reviews, the larger 4 MB L2 cache vs. the smaller 2 MB L2 cache at the same frequency and FSB can provide a 0–9% performance gain with certain applications and 0–16% performance gain with certain games.
https://en.wikipedia.org/wiki?curid=24099628
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Originally German Air Force aircraft carried an Iron Cross — appearing to be closely modeled on that used by the 1916-17 era Imperial German through the spring of 1918, but no longer having the white border around the crosses' "ends" (thusly resembling the orthogonal white "flanks" of the earlier, 1918-1945 era national marking) — as an identifying feature on all four wing positions and on both sides on the rear of the fuselage and a small tricolor German flag painted on the vertical stabilizer. Each aircraft also carried a serial number consisting of 2 letters, which identified the service and combat wing, followed by three numbers identifying the squadron and the number of the plane within the squadron, almost graphically resembling the USAF's own buzz numbers of the same period.
https://en.wikipedia.org/wiki?curid=1030130
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A privately funded project, of William Lovelace, the Woman in Space Program recruited women pilots in the U.S. to test them for suitability for the space program. Thirteen of the recruits passed NASA's physical requirements. Scheduled for additional testing, the United States Navy canceled use of their facilities as there were no NASA officials involved. Public hearings were held by a special Subcommittee of the House Committee on Science and Astronautics in 1962. Because NASA required all astronauts to attain an engineering degree and be graduates of military jet piloting test programs, none of the women could meet the entry prerequisites. The subcommittee took no action after the hearing. The following year, Valentina Tereshkova, an amateur Russian parachute jumper became the first woman in space.
https://en.wikipedia.org/wiki?curid=47210395
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This change constrains trackingNumbers to have a value between 0 and 199 inclusive, and questionNumbers to have a value between 10 and 20 inclusive. The size of the questions array can be between 0 and 10 elements, with the answers array between 1 and 10 elements. The anArray field is a fixed length 100 element array of integers that must be in the range 0 to 1000. The '...' extensibility marker means that the FooHistory message specification may have additional fields in future versions of the specification; systems compliant with one version should be able to receive and transmit transactions from a later version, though able to process only the fields specified in the earlier version. Good ASN.1 compilers will generate (in C, C++, Java, etc.) source code that will automatically check that transactions fall within these constraints. Transactions that violate the constraints should not be accepted from, or presented to, the application. Constraint management in this layer significantly simplifies protocol specification because the applications will be protected from constraint violations, reducing risk and cost.
https://en.wikipedia.org/wiki?curid=75625
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Some criticisms of the membrane theory developed in the 1930s, based on observations such as the ability of some cells to swell and increase their surface area by a factor of 1000. A lipid layer cannot stretch to that extent without becoming a patchwork (thereby losing its barrier properties). Such criticisms stimulated continued studies on protoplasm as the principal agent determining cell permeability properties. In 1938, Fischer and Suer proposed that water in the protoplasm is not free but in a chemically combined form, and that the protoplasm represents a combination of protein, salt and water. They demonstrated the basic similarity between swelling in living tissues and the swelling of gelatin and fibrin gels. Dimitri Nasonov (1944) viewed proteins as the central components responsible for many properties of the cell, including electrical properties.
https://en.wikipedia.org/wiki?curid=21400587
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By 1898 the RCScI had chairs of Mining and Mineralogy, Physics, Chemistry, Zoology, Botany, Geology, Applied Mathematics and Mechanism, Descriptive Geometry and Engineering. In 1900, control was transferred from the Science and Art Department in London to the Department of Agriculture and Technical Instruction in Dublin, headed by Horace Plunkett. A new building was proposed in 1897 and a site from Merrion Street to Kildare Street was chosen in 1898; in 1899 the plan was extended to include government administrative offices as well as the new college. The new building was designed by Sir Aston Webb; the foundation stone was laid in 1904 by Edward VII and it was opened in 1911 by George V.
https://en.wikipedia.org/wiki?curid=2253593
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