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Dordt offers over 90 programs of study with over 40 majors and 11 pre-professional programs of study. The core is drawn from various academic disciplines—such as language, natural science, and social science. These courses integrate the character and scope of Christian perspective. They provide insight into the nature and demands of contemporary Christian living and help students understand how various aspects of contemporary life are interrelated and how the global culture has developed. These general education courses also supply students with the basic quantitative, analytic, lingual, and physical skills that are essential to the program overall and to their tasks as citizens.
https://en.wikipedia.org/wiki?curid=446154
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The release of tephra into the troposphere impacts the environment physically and chemically. Physically, volcanic blocks damage local flora and human settlements. Ash damages communication and electrical systems, coats forests and plant life reducing photosynthesis, and pollutes groundwater. Tephra changes below- and above-ground air and water movement. Chemically, tephra release can impact the water cycle. Tephra particles can cause ice crystals to grow in clouds which increases precipitation. Nearby watersheds and the ocean can experience elevated mineral levels, especially iron, which can cause explosive population growth in plankton communities. This, in turn, can result in eutrophication.
https://en.wikipedia.org/wiki?curid=434543
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The early textile factories employed a large share of children, but the share declined over time. In England and Scotland in 1788, two-thirds of the workers in 143 water-powered cotton mills were described as children. Sir Robert Peel, a mill owner turned reformer, promoted the 1802 Health and Morals of Apprentices Act, which was intended to prevent pauper children from working more than 12 hours a day in mills. Children had started in the mills at around the age of four, working as mule scavengers under the working machinery until they were eight, they progressed to working as little piecers which they did until they were 15. During this time they worked 14 to 16 hours a day, being beaten if they fell asleep. The children were sent to the mills of Derbyshire, Yorkshire and Lancashire from the workhouses in London and other towns in the south of England. A well-documented example was that of Litton Mill. Further legislation followed. By 1835, the share of the workforce under 18 years of age in cotton mills in England and Scotland had fallen to 43%. About half of workers in Manchester and Stockport cotton factories surveyed in 1818 and 1819 had begun work at under ten years of age. Most of the adult workers in cotton factories in mid-19th-century Britain were workers who had begun work as child labourers. The growth of this experienced adult factory workforce helps to account for the shift away from child labour in textile factories.
https://en.wikipedia.org/wiki?curid=993518
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The C.23 BN.2 was designed to be a night bomber able to reach Berlin with a bomb load. The French BN.2 military category indicated a two-seat night bomber but the C.23 had a crew of three. It had much in common with the Caudron C.22 but was almost 50% larger in span, requiring an extra bay and more powerful engines. It was a large five bay biplane, with fabric covered, constant chord, unswept wings with angled tips. The upper wing, which carried the ailerons, had a slightly greater (4%) span and a smaller chord. There was no stagger, so the sets of parallel interplane struts were vertical; flying wires braced each bay. Pairs of V-form engine bearing struts, which supported the two neatly cowled Salmson 9Z nine cylinder water-cooled radial engines just above the lower wing, defined the inner two bays.
https://en.wikipedia.org/wiki?curid=46572890
1,865,060
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The Vinod Gupta School of Management (VGSOM) and Rajiv Gandhi School of Intellectual Property Law were established with donated funds from Vinod Gupta (founder, Infogroup) along with support from the government of India. VGSOM started in 1993 with a batch of 30 students. Other centres built by funding from alumni include the G.S. Sanyal School of Telecommunication and VLSI-CAD laboratory. The IIT Foundation, started by Vinod Gupta in 1992, is the alumni association of the institute with chapters in cities in India and abroad. Subrata Gupta is the Director of West Bengal Industrial Development Corporation. The alumni association publishes the quarterly newsletter "KGPian" for the alumni. The institute also publishes a monthly e-newsletter titled "KGP Konnexion" for alumni. IIT Kharagpur has a dean for alumni affairs to manage liaisons with alumni. The US-based alumni of IIT Kharagpur have started the "Vision 2020" fundraiser, to provide infrastructure (like labs and equipment) and attract and retain faculty and students. The objective of Vision 2020 is to raise a $200 million endowment fund by 2020 for technology education, research and innovation related growth of the institute. On 20 April 2013 ex-graduates from IIT Kharagpur formed a group "Kharagpur-in-Mumbai group" and held a meeting in Bandra, Mumbai to chalk out "the easiest and pragmatic ways" on how they can given back to society.
https://en.wikipedia.org/wiki?curid=294901
353,537
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Cells are the building blocks of all living organisms. Within these cells are coils of DNA, genetic information instructing for how cells will develop and operate. A small segment of DNA is a gene which codes for the making of proteins and passing on traits to offspring in reproduction. The main goal of a gene is to reproduce and thrive in its environment in relative to competitors. Practical implications in crime investigation, disorders and increasingly talent prediction and career decision making have considered their association with genes and biology, but the idea of biology and marketing is a growing body of knowledge. Neuromarketing is a new phenomenon studying consumer's reactions to marketing stimuli.
https://en.wikipedia.org/wiki?curid=35557898
1,875,661
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He qualified in architecture from the AA (Architectural Association) School of Architecture (London) where he did freelance illustrations and graphic work for the AD, AAQ magazines and for the AA. His dissertation at Cambridge University, "A Theoretical Framework for Incorporating Ecological Considerations in the Design and Planning of the Built Environment" earned him a PhD, published as ‘Designing With Nature’ (McGraw-Hill, 1995) and as 'Proyectar Con La Naturaleza’ (Gustavo Gili, SA, 1999). Academically, he holds the Distinguished Plym Professor chair (University of Illinois, USA, 2005). His honorary degrees include D.Litt.(Hon.) (Sheffield University, UK 2004), PhD (Hon.) (University of Malaya, 2013), D. Arch (Hon.) (Universidad Ricardo Palma, Peru 2016), D.Sc (Hon..) (Taylors University, Malaysia 2017).
https://en.wikipedia.org/wiki?curid=1879224
1,149,567
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From 1853 to 1860 Billroth was an assistant in Bernhard von Langenbeck’s surgical clinic at the Charité in Berlin. There he was also apprenticed to Carl Langenbuch. In 1860, Billroth accepted an offer from the University of Zurich to become the Chair of Clinical Surgery, becoming director of the surgical hospital and clinic in Zurich. The beginning of his career in Switzerland was unpromising: during his first semester of teaching, he had only ten students, and he himself said that the income he received from his private practice was insufficient to pay for his morning cup of coffee. His reputation quickly grew however; Billroth had an infectious personality, attracting both students and surgical trainees to his ranks. He was loved by his students, and was an effective undergraduate as well as graduate teacher. Students flocked to his lectures, and with the cooperation of energetic colleagues, he was able to raise the Medical Faculty of Zurich to a prominent position among German speaking schools in only a few years.
https://en.wikipedia.org/wiki?curid=660004
1,291,347
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In 1986, the building no longer housed an art school. The building, purchased by Altro Health and Rehabilitation Services, was used as vocational training center. Touro College purchased the building in 1990 or 1991. In 1992, the building underwent a $750,000 renovation, led by the architectural firm Lemberger Brody Associates, and became the school's Lexington Avenue campus, It has ten classrooms, a library, two reading rooms, and a laboratory. The building retains its oversized windows and skylights. Classes began in September 1992. Touro sold it in 2006 to Lexington Landmark Properties. It is now the site of Dover Street Market, having undergone an architectural project that reflects the design aesthetics of founder Rei Kawakubo, which was implemented by architect Richard H. Lewis. Within the interior of the building, is a glass elevator, three 60-foot pillars, and art installations.
https://en.wikipedia.org/wiki?curid=11571844
1,824,290
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David Karnofsky was the son of Lithuanian Jewish immigrants, Sam Karnofsky, a metals buyer, and Lena Karnofsky. David graduated from Belmont High School (Los Angeles, California) (1930), UCLA 1934. He received his masters (A.M, 1936) in biology from Stanford University with a thesis entitled "Some effects of thyroidectomy on the mammary glands and some other organs in the rat." He received his medical degree (Alpha Omega Alpha 1940), also from Stanford University. In the early years of his career at the Collis P. Huntington Memorial Laboratory at Harvard University, he became interested in clinical cancer research. This interest was further fueled by experiments he conducted during World War II as part of the Army Chemical Warfare Service.
https://en.wikipedia.org/wiki?curid=48851280
1,981,612
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Chemically, transesterified biodiesel comprises a mix of mono-alkyl esters of long chain fatty acids. The most common form uses methanol (converted to sodium methoxide) to produce methyl esters (commonly referred to as Fatty Acid Methyl Ester – FAME) as it is the cheapest alcohol available, though ethanol can be used to produce an ethyl ester (commonly referred to as Fatty Acid Ethyl Ester – FAEE) biodiesel and higher alcohols such as isopropanol and butanol have also been used. Using alcohols of higher molecular weights improves the cold flow properties of the resulting ester, at the cost of a less efficient transesterification reaction. A lipid transesterification production process is used to convert the base oil to the desired esters. Any free fatty acids (FFAs) in the base oil are either converted to soap and removed from the process, or they are esterified (yielding more biodiesel) using an acidic catalyst. After this processing, unlike straight vegetable oil, biodiesel has combustion properties very similar to those of petroleum diesel, and can replace it in most current uses.
https://en.wikipedia.org/wiki?curid=188551
384,057
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Similar to all non-avian dinosaurs studied to date, "Plateosaurus" grew in a pattern that is unlike that of both extant mammals and birds. In the closely related sauropods with their typical dinosaurian physiology, growth was initially rapid, continuing somewhat more slowly well beyond sexual maturity, but was determinate, i.e. the animals stopped growing at a maximum size. Mammals grow rapidly, but sexual maturity falls typically at the end of the rapid growth phase. In both groups, the final size is relatively constant, with humans atypically variable. Extant reptiles show a sauropod-like growth pattern, initially rapid, then slowing after sexual maturity, and almost, but not fully, stopping in old age. However, their initial growth rate is much lower than in mammals, birds and dinosaurs. The reptilian growth rate is also very variable, so that individuals of the same age may have very different sizes, and final size also varies significantly. In extant animals, this growth pattern is linked to behavioural thermoregulation and a low metabolic rate (i.e. ectothermy), and is called "developmental plasticity". (Note that is not the same as neural developmental plasticity).
https://en.wikipedia.org/wiki?curid=1565138
799,401
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Experiments have been conducted on self-driving cars since 1939; promising trials took place in the 1950s and work has proceeded since then. The first self-sufficient and truly autonomous cars appeared in the 1980s, with Carnegie Mellon University's Navlab and ALV projects in 1984 and Mercedes-Benz and Bundeswehr University Munich's Eureka Prometheus Project in 1987. Since then, numerous major companies and research organizations have developed working autonomous vehicles including Mercedes-Benz, General Motors, Continental Automotive Systems, Autoliv Inc., Bosch, Nissan, Toyota, Audi, Volvo, Vislab from University of Parma, Oxford University and Google. In July 2013, Vislab demonstrated BRAiVE, a vehicle that moved autonomously on a mixed traffic route open to public traffic.
https://en.wikipedia.org/wiki?curid=44787757
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In chapter 6 of book I the "Physics" Aristotle argues that any change must be analysed in reference to the property of an invariant subject: as it was before the change and thereafter. Thus, in his hylomorphic account of change, "matter" serves as a relative substratum of transformation, i.e., of changing (substantial) form. In the "Categories", properties are predicated only of substance, but in chapter 7 of book I of the "Physics", Aristotle discusses substances coming to be and passing away in the "unqualified sense" wherein primary substances (πρῶται οὐσίαι; "Categories" 2a35) are generated from (or perish into) a material substratum by having gained (or lost) the essential property that formally defines substances of that kind (in the secondary sense). Examples of such a substantial change include not only conception and dying, but also metabolism, e.g., the bread a man eats becomes the man. On the other hand, in accidental change, because the essential property remains unchanged, by identifying the substance with its formal essence, substance may thereby serve as the relative subject matter or property-bearer of change in a qualified sense (i.e., barring matters of life or death). An example of this sort of accidental change is a change of color or size: a tomato becomes red, or a juvenile horse grows.
https://en.wikipedia.org/wiki?curid=27568
988,510
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A 10th-century astronomer deduced that there were around 1000 applications for the astrolabe's various functions, and these ranged from the astrological, the astronomical and the religious, to seasonal and daily time-keeping and tide tables. At the time of their use, astrology was widely considered as much of a serious science as astronomy, and study of the two went hand-in-hand. The astronomical interest varied between folk astronomy (of the pre-Islamic tradition in Arabia) which was concerned with celestial and seasonal observations, and mathematical astronomy, which would inform intellectual practices and precise calculations based on astronomical observations. In regards to the astrolabe's religious functionality, the demands of Islamic prayer times were to be astronomically determined to ensure precise daily timings, and the qibla, the direction of Mecca towards which Muslims must pray, could also be determined by this device. In addition to this, the lunar calendar that was informed by the calculations of the astrolabe was of great significance to the religion of Islam, given that it determines the dates of important religious observances such as Ramadan.
https://en.wikipedia.org/wiki?curid=73664
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There are 3,442 international students enrolled at the TU Dresden (2005–2006). Most of the foreign students come from Europe (1,527), followed by Asia (1,404) and America (170). Ranked by countries the largest group of students comes from China (710), followed by Poland (294), Vietnam (196), Bulgaria (160) and Russia (154). The university is also quite popular among Central and East European countries such as the neighboring Czech Republic or Ukraine. Also, through the Erasmus programme and partnerships with universities in the USA, there are many English-, French- and Spanish-speaking students. The language spoken during lessons is nearly always German on most faculties. To prepare for admissions to the university, many foreign students attend German language courses at the university-affiliated language school .
https://en.wikipedia.org/wiki?curid=827048
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The idea of using aspirin to prevent clotting diseases (such as heart attacks and strokes) was revived in the 1960s, when medical researcher Harvey Weiss found that aspirin had an anti-adhesive effect on blood platelets (and unlike other potential antiplatelet drugs, aspirin had low toxicity). Medical Research Council haematologist John O'Brien picked up on Weiss's finding and, in 1963, began working with epidemiologist Peter Elwood on aspirin's anti-thrombosis drug potential. Elwood began a large-scale trial of aspirin as a preventive drug for heart attacks. Nicholas Laboratories agreed to provide aspirin tablets, and Elwood enlisted heart attack survivors in a double-blind controlled study—heart attack survivors were statistically more likely to suffer a second attack, greatly reducing the number of patients necessary to reliably detect whether aspirin had an effect on heart attacks. The study began in February 1971, though the researchers soon had to break the double-blinding when a study by American epidemiologist Hershel Jick suggested that aspirin prevented heart attacks but suggested that the heart attacks were more deadly. Jick had found that fewer aspirin-takers were admitted to his hospital for heart attacks than non-aspirin-takers, and one possible explanation was that aspirin caused heart attack sufferers to die before reaching the hospital; Elwood's initial results ruled out that explanation. When the Elwood trial ended in 1973, it showed a modest but not statistically significant reduction in heart attacks among the group taking aspirin.
https://en.wikipedia.org/wiki?curid=16283254
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The "chiral pitch", p, refers to the distance over which the LC molecules undergo a full 360° twist (but note that the structure of the chiral nematic phase repeats itself every half-pitch, since in this phase directors at 0° and ±180° are equivalent). The pitch, p, typically changes when the temperature is altered or when other molecules are added to the LC host (an achiral LC host material will form a chiral phase if doped with a chiral material), allowing the pitch of a given material to be tuned accordingly. In some liquid crystal systems, the pitch is of the same order as the wavelength of visible light. This causes these systems to exhibit unique optical properties, such as Bragg reflection and low-threshold laser emission, and these properties are exploited in a number of optical applications. For the case of Bragg reflection only the lowest-order reflection is allowed if the light is incident along the helical axis, whereas for oblique incidence higher-order reflections become permitted. Cholesteric liquid crystals also exhibit the unique property that they reflect circularly polarized light when it is incident along the helical axis and elliptically polarized if it comes in obliquely.
https://en.wikipedia.org/wiki?curid=17973
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This problem has led to nearly the end of use for a common base metal alloy for everyday coinage in the 20th century, called cupronickel, with varying proportions of copper and nickel, most commonly 75% Cu 25% Ni. Cupronickel has a silver color, is hard wearing and has excellent striking properties, essential for the design of the coin to be pressed accurately and quickly during manufacture. In the 21st century with the prices of both copper and nickel rising, it has become more common to experiment with various alloys of steel, often stainless steel. For example, in India some coins have been made from a stainless steel that contains 82% iron, 18% chromium, and many other countries that have minted coins that contain metals now worth nearly the coin face-value, are experimenting with various steel alloys.
https://en.wikipedia.org/wiki?curid=26421394
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Studies of the safety of FieldTurf are conflicting. A five-year study funded by FieldTurf and published in the "American Journal of Sports Medicine" found that injury rates for high-school sports were similar on natural grass and synthetic turf. However, notable differences in the types of injuries were found. Athletes playing on synthetic turf sustained more skin injuries and muscle strains, while those who played on natural grass were more susceptible to concussions and ligament tears. In 2010, another FieldTurf-funded but peer-reviewed study was published in the "American Journal of Sports Medicine", this time on NCAA Division I-A football, concluding that in many cases, games played on FieldTurf-branded products led to fewer injuries than those played on natural grass. However, the NFL's Injury and Safety Panel presented a study finding that anterior cruciate ligament (ACL) injuries happened 88% more often in games played on FieldTurf than in games played on grass. In 2012, the Injury and Safety Panel published an independently funded analysis of actual game data over the 2000–2009 seasons. Their statistically significant findings showed a 67% higher rate of ACL sprains and 31% higher rate of eversion ankle sprains.
https://en.wikipedia.org/wiki?curid=1039766
962,958
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Unlike receptor tyrosine kinases, nRTKs lack receptor-like features such as an extracellular ligand-binding domain and a transmembrane-spanning region. Most of the nRTKs are localized in the cytoplasm, but some nRTKs are anchored to the cell membrane through amino-terminal modification. These enzymes commonly have a modular construction and individual domains are joined together by flexible linker sequences. One of the important domain of nRTKs is the tyrosine kinase catalytic domain, which is about 275 residues in length. The structure of the catalytic domain can be divided into a small and a large lobe, where ATP binds to the small lobe and the protein substrate binds to the large lobe. Upon the binding of ATP and substrate to nRTKs, catalysis of phosphate transfer occurs in a cleft between these two lobes. It was found that nRTKs have some sequence preference around the target Tyr. For example, the Src preferred sequence is Glu–Glu/Asp–Ile–Tyr–Gly/Glu–Glu–Phe and Abl preferred sequence is Ile/Val–Tyr–Gly–Val–Leu/Val. Different preferred sequences around Tyr in Src and Abl suggest that these two types of nRTKs phosphorylates different targets.
https://en.wikipedia.org/wiki?curid=20149100
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The major complication of IVF is the risk of multiple births. This is directly related to the practice of transferring multiple embryos at embryo transfer. Multiple births are related to increased risk of pregnancy loss, obstetrical complications, prematurity, and neonatal morbidity with the potential for long term damage. Strict limits on the number of embryos that may be transferred have been enacted in some countries (e.g. Britain, Belgium) to reduce the risk of high-order multiples (triplets or more), but are not universally followed or accepted. Spontaneous splitting of embryos in the womb after transfer can occur, but this is rare and would lead to identical twins. A double blind, randomised study followed IVF pregnancies that resulted in 73 infants (33 boys and 40 girls) and reported that 8.7% of singleton infants and 54.2% of twins had a birth weight of less than . There is some evidence that making a double embryo transfer during one cycle achieves a higher live birth rate than a single embryo transfer; but making two single embryo transfers in two cycles has the same live birth rate and would avoid multiple pregnancies.
https://en.wikipedia.org/wiki?curid=57880
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Ependymal cells actively regulate neuronal fate specification of adult neural precursors through release of Noggin. Beating of the cilia of ependymal cells appears to set up concentration gradients of guidance molecules, such as cytokines TNF-α (tumor necrosis factor) and IGF-1 (insulin-like growth factor), to direct migration of neuroblasts, such as in the RMS. Microglia also actively regulate adult neurogenesis. Under basal conditions, apoptotic corpses of newly generated neurons are rapidly phagocytosed from the niche by unactivated microglia in the adult SGZ. Under inflammatory conditions, reactivated microglia can have both beneficial and detrimental effects on different aspects of adult neurogenesis, depending on the balance between secreted molecules with pro- and anti-inflammatory action. In one study, the activation of microglia and recruitment of T cells were suggested to be required for enriched environment-induced SGZ neurogenesis, suggesting a possible role in the RMS.
https://en.wikipedia.org/wiki?curid=2904663
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Her key contribution to social psychology relates to implicit theories of intelligence, described in her 2006 book "Mindset: The New Psychology of Success". According to Dweck, individuals can be placed on a continuum according to their implicit views of where ability comes from. Some believe their success is based on innate ability; these are said to have a "fixed" theory of intelligence (fixed mindset). Others, who believe their success is based on hard work, learning, training and doggedness are said to have a "growth" or an "incremental" theory of intelligence (growth mindset). Individuals may not necessarily be aware of their own mindset, but their mindset can still be discerned based on their behavior. It is especially evident in their reaction to failure. Fixed-mindset individuals dread failure because it is a negative statement on their basic abilities, while growth mindset individuals don't mind or fear failure as much because they realize their performance can be improved and learning comes from failure. These two mindsets play an important role in all aspects of a person's life. Dweck argues that the growth mindset will allow a person to live a less stressful and more successful life. Dweck's definition of fixed and growth mindsets from a 2012 interview:
https://en.wikipedia.org/wiki?curid=10619739
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The 15th Combat Engineer Battalion was reactivated at Fort Lewis, and stationed on North Fort, in June 1972. In 1983, Delta Company was reorganized as a General Support Heavy Engineer Company, and the Bridge Company became Echo Company. On 1 April 1984, Echo Company reorganized to form the 73rd Engineer Company(Assault Ribbon Bridge), I Corps, and attached them to the 15th Combat Engineer Battalion. In 1988 Alpha Company was called to support the fire fighting efforts in Yellowstone National Park Wy. After 3 days of training they were deployed in August 1988 at base camp Madison Junction until the fire was out in September 1988 by the snow. The unit soldiers were awarded, 2 months later, the Humanitarian Service Medal for their efforts. During July and August 1989 the 15th Engineer Battalion conducted firefighting operations in the Wallowa-Whitman National Forest near Baker, Oregon as a part of OPERATION FIREBREAK. Participating soldiers were subsequently awarded the Humanitarian Service Medal. In January 1990, the Army ordered the 9th Infantry Division to inactivate. Charlie Company cased its guidon on 1 October 1990. Delta Company inactivated on 14 February 1991, when it reorganized to form the nucleus of the 102nd Engineer Company, 199th Infantry Brigade (Motorized). Soldiers and equipment from across the battalion were used to fill the new company. The 73rd Engineer Company(ARB), after its three-month combat tour in Operation Desert Storm, returned to I Corps control and was attached to 864th Engineer Battalion until its inactivation in 1994. The remaining companies and the battalion Headquarters inactivated on 1 August 1991.
https://en.wikipedia.org/wiki?curid=17862539
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From 10 to 14 August, Carlsen participated in the fourth leg of the 2019 Grand Chess Tour, the St. Louis Rapid & Blitz. He had a poor showing, scoring 8/18 (+3−4=2, points doubled) in rapid and 9/18 (+6−6=6) in blitz for a combined total of 17/36, putting him in sixth place. He said at the end of the first day of blitz: "Everything's going wrong. My confidence is long gone ... At this point I just don't care anymore and I'm just waiting for the classical to start." The fifth leg, the 7th Sinquefield Cup, was a classical tournament. Carlsen won his last two games to tie for first on 6½/11 (+2−0=9) with Ding, but lost the tiebreak 1–3, drawing both rapid games then losing two consecutive blitz games.
https://en.wikipedia.org/wiki?curid=442682
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Alan Merriam addresses issues that he found with ethnomusicological fieldwork in the third chapter of his 1964 book, "The Anthropology of Music". One of his most pressing concerns is that, as of 1964 when he was writing, there had been insufficient discussion among ethnomusicologists about how to conduct proper fieldwork. That aside, Merriam proceeds to characterize the nature of ethnomusicological fieldwork as being primarily concerned with the collection of facts. He describes ethnomusicology as both a field and a laboratory discipline. In these accounts of the nature of ethnomusicology, it seems to be closely related to a science. Because of that, one might argue that a standardized, agreed-upon field method would be beneficial to ethnomusicologists. Despite that apparent viewpoint, Merriam conclusively claims that there should be a combination of a standardized, scientific approach and a more free-form analytical approach because the most fruitful work he has done has come from combining those two rather than separating them, as was the trend among his contemporaries.
https://en.wikipedia.org/wiki?curid=80077
934,076
1,984,831
Non-invasive genetic testing can be used to infer possible interstitial lung disorders caused by surfactant metabolism dysfunction. Although these sequencing tests can take up to several weeks, which may not be so useful in case of acute respiratory problems in newborns. Overlapping phenotypes of surfactant metabolism dysfunction and other interstitial lung diseases make it hard to propose definitive diagnosis for surfactant disorders. Overall testings, family history, external factors, and clinical presentations should all be considered to diagnose surfactant metabolism dysfunction. Testing for surfactant metabolism dysfunction should be considered for newborns with diffuse lung disease or hypoxemia, especially in families with history of neonatal lung diseases or ILD in adults. Neonatal and adult onset lung diseases with unfound causes should also be tested early for surfactant dysfunction. ABCA3 and SP-B dysfunctions manifest in newborns and progress aggressively within the first few months of life, thus, testing for ABCA3 and SP-B disorders should preclude those for SP-C, especially when infants are showing symptoms of ILD or diffuse lung disease. Distinctions between SP-B and ABCA3 are ABCA3 tends to occur in families with neonatal lung disease history, and SP-B testing almost unneeded in older children. Late on-set conditions with inheritance in dominant fashion should infer SP-C dysfunction. Antibodies against proSP-B, proSP-C, SP-B, SP-C, and ABCA3 have been thoroughly developed, which makes detection for these proteins highly accessible and accurate. Immuno staining of each of these type of surfactant dysfunction differs in absence and presence of specific proteins and propeptides, thus immunohistochemisty can help decipher which type of deficiency is being dealt with. In addition, hypothyroidism can cause damaged production of NKX2.1 proteins, which can lead to insufficient transcription of multiple surfactant proteins.
https://en.wikipedia.org/wiki?curid=30022078
1,983,692
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Due to their similarities to humans, researchers have been interested in looking into the episodic memory abilities of non-human primates. However, little uncritisized research has previously been done. For example, Schwartz performed an experiment with gorillas in a task requiring the animal to select the appropriate card that represented the food he had just eaten and who had given it to him. While the gorilla appropriately identified the food items and trainer, it is unclear if he recalled the event or chose the answer most familiar to him. Menzel also showed evidence of episodic memory in apes, however, an alternative explanation is that the chimpanzees were displaying spatial semantic memory. Furthermore, Hampton had mixed results when testing rhesus monkeys; while demonstrating memory for the location and type of food, they lacked sensitivity to when they acquired the knowledge. Thus, more research was required for this type of memory in non-human primates.
https://en.wikipedia.org/wiki?curid=34731827
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A major discovery was made by a French Army physician Charles Louis Alphonse Laveran working in Algeria, North Africa. At the hospital in Bône (now Annaba), he noticed spherical bodies from a patient's blood film, free or adherent to red blood cells. On 6 November 1880 he observed from one patient's blood the actual living parasite, describing it as "a pigmented spherical body, filiform elements which move with great vivacity, displacing the neighboring red blood cells." He also observed the process of maturation of the parasite (which is now called exflagellation of microgametocytes). He meticulously examined 200 patients, and noted the cellular bodies in all 148 cases of malaria but never in those without malaria. He also found that after treatment with quinine, the parasites disappeared from blood. These findings clearly indicated that the parasite was the cause of malaria, and establishing the germ theory (nature) of malaria. He named the parasite "Oscillaria malariae" (later renamed "Plasmodium malariae") and reported his discovery to the French Academy of Medicine in Paris on 23 November and 28 December. For his discovery he was awarded the Nobel Prize for Physiology or Medicine in 1907.
https://en.wikipedia.org/wiki?curid=42553902
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The surface computer stamped the date and time of collection directly onto the SP image. Custom software integrated an NMEA data stream from a GPS connected to the computer's serial port to also stamp the geographic position of the surface vessel (or of the device if corrected by NMEA output from an acoustic positioning beacon array). The software further uses a modification of the GEOTiff graphic standard to embed geographic position and datum information into the image tags. This permits automatic placement of SPI and seabed surface images into spatially appropriate positions when opening within a GIS package. This functionality allows real time assessment of benthic data in the field to inform further sampling decisions.
https://en.wikipedia.org/wiki?curid=14917968
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More recently, researchers demonstrated that indoor lights such as fluorescent lights and incandescent bulbs vary their light intensity in accordance with the voltage supplied, which in turn depends on the voltage supply frequency. As a result, the light intensity can carry the frequency fluctuation information to the visual sensor recordings in a similar way as the electromagnetic waves from the power transmission lines carry the ENF information to audio sensing mechanisms. Based on this result, researchers demonstrated that visual track from still video taken in indoor lighting environments also contain ENF traces that can be extracted by estimating the frequency at which ENF will appear in a video as low sampling frequency of video (25–30 Hz) cause significant aliasing. It was also demonstrated in the same research that the ENF signatures from the visual stream and the ENF signature from the audio stream in a given video should match. As a result, the matching between the two signals can be used to determine if the audio and visual track were recorded together or superimposed later.
https://en.wikipedia.org/wiki?curid=27579471
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In contrast to the ventral stream's auditory processing, information enters from the primary auditory cortex into the posterior superior temporal gyrus and posterior superior temporal sulcus. From there the information moves to the beginning of the dorsal pathway, which is located at the boundary of the temporal and parietal lobes near the Sylvian fissure. The first step of the dorsal pathway begins in the sensorimotor interface, located in the left Sylvian parietal temporal (Spt) (within the Sylvian fissure at the parietal-temporal boundary). The spt is important for perceiving and reproducing sounds. This is evident because its ability to acquire new vocabulary, be disrupted by lesions and auditory feedback on speech production, articulatory decline in late-onset deafness and the non-phonological residue of Wernicke's aphasia; deficient self-monitoring. It is also important for the basic neuronal mechanisms for phonological short-term memory. Without the Spt, language acquisition is impaired. The information then moves onto the articulatory network, which is divided into two separate parts. The articulatory network 1, which processes motor syllable programs, is located in the left posterior inferior temporal gyrus and Brodmann's area 44 (pIFG-BA44). The articulatory network 2 is for motor phoneme programs and is located in the left M1-vBA6.
https://en.wikipedia.org/wiki?curid=2956315
800,212
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In an attempt to boost the performance of the Spitfire Mk1 in May 1940, RAe scientists (including Hayne Constant) developed a 'propulsive duct'. This was in essence a simple ram jet, fed by petrol, utilising the Meredith effect. It was housed in a deep duct mounted on the fuselage centre line and resembled a third radiator. Bench tests showed that the increase in speed was not significant and the device was not flight tested. In 1943 the idea was reconsidered as a counter to the threat of the V1. Aircraft such as the Hawker Tempest and Gloster Meteor were not widely available and the Spitfire would only be able to intercept in a diving attack. A. D. Baxter and C. W. R. Smith at Farnborough reviewed the 1940 work and concluded that it was practical but problems with drag and pressure loss were encountered and the V1 had been beaten before they were solved.
https://en.wikipedia.org/wiki?curid=18854512
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Supraglottic techniques use devices that are designed to have the distal tip resting above the level of the glottis when in its final seated position. Supraglottic devices ensure patency of the upper respiratory tract without entry into the trachea by bridging the oral and pharyngeal spaces. There are many methods of subcategorizing this family of devices including route of insertion, absence or presence of a cuff, and anatomic location of the device's distal end. The most commonly used devices are laryngeal masks and supraglottic tubes, such as oropharyngeal (OPA) and nasopharyngeal airways (NPA). In general, features of an ideal supraglottic airway include the ability to bypass the upper airway, produce low airway resistance, allow both positive pressure as well as spontaneous ventilation, protect the respiratory tract from gastric and nasal secretions, be easily inserted by even a nonspecialist, produce high first-time insertion rate, remain in place once in seated position, minimize risk of aspiration, and produce minimal side effects.
https://en.wikipedia.org/wiki?curid=660843
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In 1977, Atari released its CPU-based console called the Video Computer System (VCS), later called the Atari 2600. Nine games were designed and released for the holiday season. Atari held exclusive rights to most of the popular arcade game conversions of the day. They used this key segment to support their older hardware in the market. This game advantage and the difference in price between the machines meant that each year, Atari sold more units than Intellivision, lengthening its lead despite inferior graphics. The Atari 2600 sold over 30 million units over its lifetime, considerably more than any other console of the second generation. In 1982, Atari released the Atari 5200 in an attempt to compete with the Intellivision. While superior to the 2600, poor sales and lack of new games meant Atari only supported it for two years before it was discontinued.
https://en.wikipedia.org/wiki?curid=3442219
171,664
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Category 5 Hurricane Michael opened up a lot of canopy October 2018. Monitoring was initiated right after rescue operations removed woody debris crushing some of the existing stems. Post-hurricane disaster funds were also provided to a new, locally based citizen group called TorreyaKeepers, who organized as a segment of the Florida Native Plants Society. A major accomplishment was the ability of this citizen group to obtain permission from private landowners in Torreya's native range and thereby document more wild specimens — and collect cuttings that Atlanta Botanical Garden then rooted and added to their living collections for safeguarding even more genetic diversity than they already had acquired.
https://en.wikipedia.org/wiki?curid=2680498
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The aircraft's dual Pratt & Whitney F119-PW-100 augmented turbofan engines are closely spaced and incorporate pitch-axis thrust vectoring nozzles with a range of ±20 degrees; the nozzles are fully integrated into the F-22’s flight controls and vehicle management system. Each engine has maximum thrust in the 35,000 lbf (156 kN) class. The F-22's thrust-to-weight ratio at typical combat weight is nearly at unity in maximum military power and 1.25 in full afterburner. The caret inlets generate oblique shocks with the upper inboard corners to ensure good total pressure recovery and efficient supersonic flow compression. Maximum speed without external stores is approximately Mach 1.8 at military power and greater than Mach 2 with afterburners.
https://en.wikipedia.org/wiki?curid=66299
2,633
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In the early 20th century, plant breeders realized that Mendel's findings on the non-random nature of inheritance could be applied to seedling populations produced through deliberate pollinations to predict the frequencies of different types. Wheat hybrids were bred to increase the crop production of Italy during the so-called "Battle for Grain" (1925–1940). Heterosis was explained by George Harrison Shull. It describes the tendency of the progeny of a specific cross to outperform both parents. The detection of the usefulness of heterosis for plant breeding has led to the development of inbred lines that reveal a heterotic yield advantage when they are crossed. Maize was the first species where heterosis was widely used to produce hybrids.
https://en.wikipedia.org/wiki?curid=30876044
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Newton's tract "De motu corporum in gyrum", which he sent to Halley in late 1684, derived what is now known as the three laws of Kepler, assuming an inverse square law of force, and generalised the result to conic sections. It also extended the methodology by adding the solution of a problem on the motion of a body through a resisting medium. The contents of "De motu" so excited Halley by their mathematical and physical originality and far-reaching implications for astronomical theory, that he immediately went to visit Newton again, in November 1684, to ask Newton to let the Royal Society have more of such work. The results of their meetings clearly helped to stimulate Newton with the enthusiasm needed to take his investigations of mathematical problems much further in this area of physical science, and he did so in a period of highly concentrated work that lasted at least until mid-1686.
https://en.wikipedia.org/wiki?curid=48781
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The fungus grows in coniferous forests in its native range, and pine plantations in countries where it has become naturalised. It forms symbiotic ectomycorrhizal associations with living trees by enveloping the tree's underground roots with sheaths of fungal tissue, and is sometimes parasitised by the related mushroom "Gomphidius roseus". "Suillus bovinus" produces spore-bearing fruit bodies, often in large numbers, above ground. The mushroom has a convex grey-yellow or ochre cap reaching up to in diameter, which flattens with age. Like other boletes, it has tubes extending downward from the underside of the cap, rather than gills; spores escape at maturity through the tube openings, or pores. The pore surface is yellow. The stipe, more slender than those of other "Suillus" boletes, lacks a ring.
https://en.wikipedia.org/wiki?curid=8221341
1,137,771
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The Martin Company spent about $3 million, employing almost 300 persons for the better part of the six-month term, to produce the most elaborate study of the three, not only following all the Space Task Group guidelines, but also going far beyond in systems analysis. The complete proposal consisted of 9,000 pages. Focusing on versatility, flexibility, safety margins, and growth, this was the only study that detailed the progression of steps from lunar orbiting to lunar landing. Martin's spacecraft would have been similar to the Apollo spacecraft that ultimately emerged. When Martin later entered the Apollo hardware procurement contract competition, NASA scored them highest of all the entrants on configuration design.
https://en.wikipedia.org/wiki?curid=36082139
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He was a senior visiting scientist at the Max Planck Institute for Chemistry, Mainz, in 1980-81, later joining CNRS Nice as a senior research associate 1984-85, and as a fellow of the Institute for the Study of the Earth's Interior (Misasa, Japan) 1997-98, returning in 2001-02 as a research fellow and afterwards as a member of its advisory panel. He also worked as a visiting associate of the California Institute of Technology 1998-99, primarily in geological and planetary sciences. He has served as chairman and managing director of university "spin-out" StatSci Europe, and as a director of Prolysis; he has also worked as a consultant to several companies in the petrochemical and energy sectors, including Royal Dutch Shell and Chevron.
https://en.wikipedia.org/wiki?curid=9557531
2,112,057
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Su Song was of Hokkien ancestry who was born in modern-day Fujian, near medieval Quanzhou. Like his contemporary, Shen Kuo (1031–1095), Su Song was a polymath, a person whose expertise spans a significant number of different fields of study. It was written by his junior colleague and Hanlin scholar Ye Mengde (1077–1148) that in Su's youth, he mastered the provincial exams and rose to the top of the examination list for writing the best article on general principles and structure of the Chinese calendar. From an early age, his interests in astronomy and calendrical science led him onto a distinguished path as a state bureaucrat. In his spare time, he was fond of writing poetry, which he used to praise the works of artists such as the painter Li Gonglin (1049–1106). He was also an antiquarian and collector of old artworks from previous dynasties.
https://en.wikipedia.org/wiki?curid=1861611
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Discovery of faults has been greatly facilitated with the development of LIDAR, a technique that can generally penetrate forest canopy and vegetation to image the actual ground surface with an unprecedented accuracy of approximately one foot (30 cm). An informal consortium of regional agencies has coordinated LIDAR mapping of much of the central Puget Lowland, which has led to discovery of numerous fault scarps which are then investigated by trenching (paleoseismology). Marine seismic reflection surveys on Puget Sound where it cuts across the various faults have provided cross-sectional views of the structure of some of these faults, and an intense, wide-area combined on-shore/off-shore study in 1998 (Seismic Hazards Investigation in Puget Sound, or SHIPS) resulted in a three-dimensional model of much of the subsurface geometry. Aeromagnetic surveys, seismic tomography, and other studies have also contributed to locating and understanding these faults.
https://en.wikipedia.org/wiki?curid=27651043
1,268,953
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The family returned to Downe on 27 August, and Darwin again wrote to the "Gardeners' Chronicle" appealing for assistance as he was "very anxious to examine a few exotic forms". His requests to the wealthy enthusiasts who had taken up the fashionable pursuit of growing rare orchids brought large numbers of specimens. These would be a test of his theory: previously aspects such as coloration of plants and animals had often been regarded as having no adaptive function. For example, Thomas Henry Huxley was strongly influenced by German idealism and in 1856 had asked if it was "to be supposed for a moment that the beauty of colour and outline ... are any "good" to the animals? ... Who has ever dreamed of finding an utilitarian purpose in the forms and colours of flowers ... ?" Darwin had, and in the orchids he tackled the most difficult case. His ideas would transform the way naturalists thought about coloration.
https://en.wikipedia.org/wiki?curid=21436165
1,741,902
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Slow sand filters are used in water purification for treating raw water to produce a potable product. They work through the formation of a biofilm called the hypogeal layer or "Schmutzdecke" in the top few millimetres of the fine sand layer. The "Schmutzdecke" is formed in the first 10–20 days of operation and consists of bacteria, fungi, protozoa, rotifera and a range of aquatic insect larvae. As an epigeal biofilm ages, more algae tend to develop and larger aquatic organisms may be present including some bryozoa, snails and annelid worms. The surface biofilm is the layer that provides the effective purification in potable water treatment, the underlying sand providing the support medium for this biological treatment layer. As water passes through the hypogeal layer, particles of foreign matter are trapped in the mucilaginous matrix and soluble organic material is adsorbed. The contaminants are metabolised by the bacteria, fungi and protozoa. The water produced from an exemplary slow sand filter is of excellent quality with 90–99% bacterial cell count reduction.
https://en.wikipedia.org/wiki?curid=43946
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The National Institute for Research in Nuclear Science (NIRNS) was formed in 1957 to operate the Rutherford High Energy Laboratory established next to the Atomic Energy Research Establishment on the former RAF Harwell airfield between Chilton and Harwell. The 50 MeV proton linear accelerator was transferred from the Atomic Energy Research Establishment to the new laboratory to become a national facility for particle physics as the Nimrod (synchrotron). Some components of this linear accelerator are still operating as part of the ISIS Neutron and Muon Source injector linac over 50 years after their first use. Since then the laboratory has grown both with the expansion of its established facilities, and the incorporation of facilities from other institutions to provide the benefits from economies of scale. The major mergers were in 1975 with the adjacent Atlas Computer Laboratory creating the Rutherford Laboratory, and then in 1979 with the Appleton Laboratory to form the current Rutherford Appleton Laboratory. With the closure of the Royal Greenwich Observatory in 1998, some small offices also moved to RAL. Similarly, laser technology moved to RAL from Joint European Torus at Culham to become the foundation of the Central Laser Facility.
https://en.wikipedia.org/wiki?curid=1237726
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Stebbins and Edgar Anderson wrote a paper in 1954 on the importance of hybridization in adapting to new environments. They proposed novel adaptations would facilitate the invasion of habitats not utilized previously by either parent and that novel adaptations may facilitate the formation of stabilized hybrid species. Following this paper, Stebbins developed the first model of adaptive radiation. He proposed that a high degree of genetic variability was necessary for major evolutionary advances, that because of slow mutation rates, genetic recombination was the most likely source of this variation, and that variation could be maximised though hybridization. As of 2006, research is ongoing regarding whether hybridization is an accidental consequence of evolution or if it is necessary for the creation and evolution of plant species; it has been argued that contemporary studies are part of an intellectual lineage that started with the work of Stebbins and Anderson.
https://en.wikipedia.org/wiki?curid=1591079
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Huxley was awarded a scholarship to spend a year at the Naples Marine Biological Station, where he developed his interest in developmental biology by investigating sea squirts and sea urchins. In 1910 he was appointed as Demonstrator in the Department of Zoology and Comparative Anatomy at the University of Oxford, and started on the systematic observation of the courtship habits of water birds, such as the common redshank (a wader) and grebes (which are divers). Bird watching in childhood had given Huxley his interest in ornithology, and he helped devise systems for the surveying and conservation of birds. His particular interest was bird behaviour, especially the courtship of water birds. His 1914 paper on the great crested grebe, later published as a book, was a landmark in avian ethology; his invention of vivid labels for the rituals (such as 'penguin dance', 'plesiosaurus race' etc.) made the ideas memorable and interesting to the general reader.
https://en.wikipedia.org/wiki?curid=145837
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In 1948, the Government of India decided that a separate Railway Coach Building Works should be established with a view to attain self-sufficiency in coaches for Indian Railways. A technical Aid Agreement was concluded on 28 May 1949 with the Swiss Car and Elevator Manufacturing Corporation Ltd. of Switzerland, who have been pioneers in the field of light-weight coach building for obtaining the necessary technical assistance in the establishment of a factory in India for building the coaches. A supplemental agreement was signed on 27 June 1953. After a comprehensive survey of several alternative sites for locating the factory, the vacant Railway land to the west of the Loco Repair Shops of the Southern Railway at Perambur was chosen as the final site in June 1951. The site is ideally situated with rail connections to the factory readily available and a nearby suburban railway station to bring workmen to the factory.
https://en.wikipedia.org/wiki?curid=3624604
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"Sculpin"s fourth war patrol, from 29 May – 17 June, was in the South China Sea. On 8 June, she was unsuccessful in an attack on a cargo ship, again due to torpedo malfunction. A vigorous depth charge attack kept "Sculpin" down while the cargo ship escaped. On 13 June, near Balabac Strait, she torpedoed a cargo ship which returned fire with her deck gun and commenced to limp away. Turning on two accompanying tankers astern of the cargo ship, "Sculpin" made an attack but was forced to dive to prevent being rammed by one of the tankers. Surfacing at dusk, "Sculpin" pursued the cargo ship, but was again driven away by accurate gunfire from the maru. She shifted her attack to a tanker, leaving the ship listing and making heavy smoke. However, no sinking was confirmed. Off Cape Varella, Indochina, early on the morning of 19 June, she torpedoed a cargo ship, making a hit forward of the stack. A heavy secondary explosion was heard, and the damaged vessel was last seen headed for the shore to beach, smoke pouring from her forward hatch. "Sculpin" returned to Australia on 17 July. She moved to Brisbane, under Ralph Waldo Christie (part of Admiral Arthur S. Carpender's 7th Fleet, and ultimately General Douglas MacArthur's South West Pacific Area command), along with the rest of Submarine Squadron Two (SubRon 2), in August.
https://en.wikipedia.org/wiki?curid=440487
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The evidence for replenishing depleted energy levels only relates when they are completely gone at the beginning of training, such as during fasted exercise. This is where large amounts of the day go by without any eating to spike and deplete energy levels to trick the body, followed by a training session (with low levels of nutritional energy) to force the body to be uncomfortable. Following this, the body is at an abnormally low level of various nutrients (such as carbohydrates and proteins), which are then put back into the body to force an even higher adaptation in the body. During fasted exercise, an increase in muscle protein breakdown causes the pre-exercise negative amino acid level to continue in the post exercise period despite increases in muscle protein synthesis. This is why it would make sense to provide immediate nutritional replenishment after exercise as there was already such a low level before training started. This would turn the catabolic state of the body into an anabolic one and therefore, promote the metabolic window as desirable. This means more or less that the body is so used to receiving food that when you starve yourself, the body does not know what to do, so it enters a panic mode where you push yourself through a depleted state, and then finally feed yourself and the body absorbs even more of the nutrients and only takes the ones needed. An example of this diet would be Intermittent Fasting.
https://en.wikipedia.org/wiki?curid=20023618
1,105,531
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During the 19th century, more chemists began to recognize the importance of glassware due to its transparency, and the ability to control the conditions of experiments. Jöns Jacob Berzelius, who invented the test tube, and Michael Faraday both contributed to the rise of chemical glassblowing. Faraday published "Chemical Manipulation" in 1827 which detailed the process for creating many types of small tube glassware and some experimental techniques for tube chemistry. Berzelius wrote a similar textbook titled "Chemical Operations and Apparatus" which provided a variety of chemical glassblowing techniques. The rise of this chemical glassblowing widened the availability of chemical experimentation and led to a shift towards the dominate use of glassware in laboratories. With the emergence of glassware in laboratories, the need for organization and standards arose. The "Prussian Society for the Advancement of Industry" was one of the earliest organizations to support the collaborative improvement of the quality of glass used.
https://en.wikipedia.org/wiki?curid=43958
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Charles did not believe that a force even twice his size on foot without archers could possibly pose him any threat. However, Charles and his forces found the pike square impossible to penetrate on horseback and dangerous to approach on foot. When threatened, the square could point all of the pikes at the enemy forces and merely move inexorably toward its target. All these considerations aside, the primary strength of the Swiss pike formation lay in its famous charge, a headlong rush against the enemy with leveled pikes and a coordinated battle cry. At Nancy, the Swiss routed the Burgundians, and Charles himself died in the battle. This success was repeated on various European battlefields, most remarkably in the early battles of the Italian Wars. With their famed discipline and in combination with heavy cavalry like the gendarme, the Swiss pike squares were almost invincible on the late medieval battlefield. The dominance of the pure pike formation only came to an end when the pike and shot formation was introduced at the end of the fifteenth century.
https://en.wikipedia.org/wiki?curid=1397903
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While the complexity, size, construction and general form of CPUs have changed enormously since 1950, the basic design and function has not changed much at all. Almost all common CPUs today can be very accurately described as von Neumann stored-program machines. As Moore's law no longer holds, concerns have arisen about the limits of integrated circuit transistor technology. Extreme miniaturization of electronic gates is causing the effects of phenomena like electromigration and subthreshold leakage to become much more significant. These newer concerns are among the many factors causing researchers to investigate new methods of computing such as the quantum computer, as well as to expand the usage of parallelism and other methods that extend the usefulness of the classical von Neumann model.
https://en.wikipedia.org/wiki?curid=5218
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In total, 114 legible letters are visible on the two sides of the fragment, representing 18 out of the 24 letters of the Greek alphabet; beta, zeta, xi, phi, chi, and psi being missing. Roberts noted that the writing is painstaking and rather laboured, with instances of individual letters formed using several strokes "with a rather clumsy effect" (e.g. the lunate sigma () at line three of the recto, and the eta () immediately following it). Several letters are inclined to stray away from the notional upper and lower writing lines. Another peculiarity is that there are two distinct forms of the letter alpha (); most are formed from a separate loop and diagonal stroke, where the top of the stroke has a distinctive decorative arch while the bottom is hooked; but on the fourth line of the verso there is a smaller alpha formed by a single spiralling loop with no arch or hooks. Also present in two forms is the letter upsilon (); the more common form is constructed from two strokes, each stroke terminating in a decorative hook or finial (see the second line of the recto); but on the fourth line of the verso is an upsilon formed from a single looped stroke with no decoration. These observations support Roberts's supposition that the scribe was an educated person writing carefully in imitation of a calligraphic hand, rather than a professional scribe writing to order; such that, on occasion, the writer inadvertently reverted to the undecorated (and often smaller) letter forms of his everyday hand.
https://en.wikipedia.org/wiki?curid=848618
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A split in the primate lineage occurred approximately 90 million years ago during the Cretaceous, which brought about two major clades: prosimians and anthropoids. The prosimians include lemurs, lorises, and galagos whereas the anthropoids comprise tarsiers, New World monkeys, Old World monkeys, and apes. Apes separated from Old World monkeys about 35 million years ago, with various species living in Africa, Europe, and Asia between 22 and 5.5 million years ago. The modern descendants of these animals include chimpanzees and gorillas in Africa, gibbons and orangutans in Asia, and humans worldwide. A split in the ape lineage occurred about six million years ago in Africa, which resulted in the emergence of chimpanzees as one group and a hominid clade as another group that includes humans and their extinct relatives. Bipedalism emerged in the earliest protohominids known as ardipithecines. As an adaptation, bipedalism conferred three advantages. First, it enabled the ardipithecines to use their forelimbs to manipulate and carry objects while working. Second, it elevated the animal's eyes to spot preys or predators over tall vegetation. Finally, bipedalism is more energetically efficient than quadrupedal locomotion.
https://en.wikipedia.org/wiki?curid=9127632
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OBE was introduced to South Africa in the late 1990s by the post-apartheid government as part of its Curriculum 2005 program. , Initial support for the program derived from anti-apartheid education policies. The policy also gained support from the labor movements that borrowed ideas about competency-based education, and Vocational education from New Zealand and Australia, as well as the labor movement that critiqued the apartheid education system. With no strong alternative proposals, the idea of outcome-based education, and a national qualification framework, became the policy of the African National Congress government. This policy was believed to be a democratization of education, people would have a say in what they wanted the outcomes of education to be. It was also believed to be a way to increase education standards and increase the availability of education. The National Qualifications Framework (NQF) went into effect in 1997. In 2001 people realized that the intended effects were not being seen. By 2006 no proposals to change the system had been accepted by the government, causing a hiatus of the program. The program came to be viewed as a failure and a new curriculum improvement process was announced in 2010, slated to be implemented between 2012 and 2014.
https://en.wikipedia.org/wiki?curid=22816
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Malarial nephropathies are reported in endemic areas, such as Southeast Asia, India, and Sub-Saharan Africa. The pathogenesis of acute kidney injury in severe malaria is unspecific and multifactorial—it affects fewer than 4.8 percent of cases, but reports a high risk of mortality (15 to 45 percent). Histologic evidence shows a large combination of pathogenic mechanisms at play—acute tubular necrosis, interstitial nephritis and glomerulonephritis. Risk factors for malarial acute kidney injury include delayed diagnosis, high parasitemia, and clinical presentation of oliguria, low blood pressure, severe anemia, and jaundice. In addition, patients already suffering from diarrhea, hepatitis, or respiratory distress have a worse prognosis.
https://en.wikipedia.org/wiki?curid=34062741
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Solar concentrating technologies such as parabolic dish, trough and Scheffler reflectors can provide process heat for commercial and industrial applications. The first commercial system was the Solar Total Energy Project (STEP) in Shenandoah, Georgia, US where a field of 114 parabolic dishes provided 50% of the process heating, air conditioning and electrical requirements for a clothing factory. This grid-connected cogeneration system provided 400 kW of electricity plus thermal energy in the form of 401 kW steam and 468 kW chilled water, and had a one-hour peak load thermal storage. Evaporation ponds are shallow pools that concentrate dissolved solids through evaporation. The use of evaporation ponds to obtain salt from seawater is one of the oldest applications of solar energy. Modern uses include concentrating brine solutions used in leach mining and removing dissolved solids from waste streams.
https://en.wikipedia.org/wiki?curid=27743
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In 2003, the National Human Genome Research Institute and its affiliated partners successfully sequenced the first whole human genome, a project that took just under $3 billion to complete. Four years later, James Watson – one of the co-discoverers of the structure of DNA – was able to sequence his genome for less than $1.5 million. As genetic sequencing technologies have proliferated, streamlined and become adapted to clinical means, they can now provide incredible insight into individual genetic identities at a much lower cost, with biotech competitors vying for the title of the $1,000 genome. Genetic material can now be extracted from a person's saliva, hair, skin, blood, or other sources, sequenced, digitized, stored, and used for numerous purposes. Whenever data is digitized and stored, there is the possibility of privacy breaches. While modern whole genome sequencing technology has allowed for unprecedented access and understanding of the human genome, and excitement for the potentialities of personalized medicine, it has also generated serious conversation about the ethics and privacy risks that accompany this process of uncovering an individual's essential instructions of being: their DNA sequence.
https://en.wikipedia.org/wiki?curid=55251966
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In 1962, the Kennedy Administration revived the requirement for a low-cost export fighter, selecting the N-156F as winner of the F-X competition on 23 April 1962, subsequently becoming the "F-5A", and was ordered into production in October that year. It was named under the 1962 United States Tri-Service aircraft designation system, which included a re-set of the fighter number series. Northrop manufactured a total of 624 F-5As, including three YF-5A prototypes, before production ended in 1972. A further 200 F-5B two-seat trainer aircraft, lacking nose-mounted cannons but otherwise combat-capable, and 86 RF-5A reconnaissance aircraft, fitted with four-camera noses, were also built. In addition, Canadair built 240 first generation F-5s under license, CASA in Spain built 70 more aircraft.
https://en.wikipedia.org/wiki?curid=11142
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Nature, traditional agriculture methods, and plant breeding have produced various uncommon crops containing anthocyanins, including blue- or red-flesh potatoes and purple or red broccoli, cabbage, cauliflower, carrots, and corn. Garden tomatoes have been subjected to a breeding program using introgression lines of genetically modified organisms (but not incorporating them in the final purple tomato) to define the genetic basis of purple coloration in wild species that originally were from Chile and the Galapagos Islands. The variety known as "Indigo Rose" became available commercially to the agricultural industry and home gardeners in 2012. Investing tomatoes with high anthocyanin content doubles their shelf-life and inhibits growth of a post-harvest mold pathogen, "Botrytis cinerea".
https://en.wikipedia.org/wiki?curid=18952492
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In 1887, the university actually maintained and staffed a sister college, Evelyn College for Women, in the town of Princeton on Evelyn and Nassau streets. It was closed after roughly a decade of operation. After abortive discussions with Sarah Lawrence College to relocate the women's college to Princeton and merge it with the University in 1967, the administration decided to admit women and turned to the issue of transforming the school's operations and facilities into a female-friendly campus. The administration had barely finished these plans in April 1969 when the admissions office began mailing out its acceptance letters. Its five-year coeducation plan provided $7.8 million for the development of new facilities that would eventually house and educate 650 women students at Princeton by 1974. Ultimately, 148 women, consisting of 100 freshmen and transfer students of other years, entered Princeton on September 6, 1969 amidst much media attention. Princeton enrolled its first female graduate student, Sabra Follett Meservey, as a PhD candidate in Turkish history in 1961. A handful of undergraduate women had studied at Princeton from 1963 on, spending their junior year there to study "critical languages" in which Princeton's offerings surpassed those of their home institutions. They were considered regular students for their year on campus, but were not candidates for a Princeton degree.
https://en.wikipedia.org/wiki?curid=35873798
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In 1961, Paul Hoppe of the U.S. Department of Agriculture studied a corn fungus by grinding up infected leaves each season, then applying the powder to test corn for the following season to track the disease. A surprise frost occurred that year, leaving peculiar results. Only plants infected with the diseased powder incurred frost damage, leaving healthy plants unfrozen. This phenomenon would baffle scientists until graduate student Stephen Lindow of the University of Wisconsin–Madison with D.C. Arny and C. Upper found a bacterium in the dried leaf powder in the early 1970s. Lindow, now a plant pathologist at the University of California-Berkeley, found that when this particular bacterium was introduced to plants where it is originally absent, the plants became very vulnerable to frost damage. He would go on to identify the bacterium as "P. syringae", investigate "P. syringae"s role in ice nucleation and in 1977, discover the mutant ice-minus strain. He was later successful at developing the ice-minus strain of "P. syringae" through recombinant DNA technology as well.
https://en.wikipedia.org/wiki?curid=9516977
1,714,053
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Sealed Ni–Cd cells consist of a pressure vessel that is supposed to contain any generation of oxygen and hydrogen gases until they can recombine back to water. Such generation typically occurs during rapid charge and discharge, and exceedingly at overcharge condition. If the pressure exceeds the limit of the safety valve, water in the form of gas is lost. Since the vessel is designed to contain an exact amount of electrolyte this loss will rapidly affect the capacity of the cell and its ability to receive and deliver current. To detect all conditions of overcharge demands great sophistication from the charging circuit and a cheap charger will eventually damage even the best quality cells.
https://en.wikipedia.org/wiki?curid=186614
170,219
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"Metasequoia" redwood fossils are known from many areas in the Northern Hemisphere; more than 20 fossil species have been named (some were even identified as the genus "Sequoia"), but are considered as just three species, "M. foxii", "M. milleri", and "M. occidentalis". Fossils are known from the Cenomanian onwards. During the Paleocene and Eocene, extensive forests of "Metasequoia" occurred as far north as Strathcona Fiord on Ellesmere Island and sites on Axel Heiberg Island (northern Canada) at around 80° N latitude. "Metasequoia" was likely deciduous by this time. Given that the high latitudes in this period were warm and tropical, it is hypothesized that the deciduous trait evolved in response to the unusual light availability patterns, not to major seasonal variations in temperature. During three months in the summer, the sun would shine continuously, while three months of the winter would be complete darkness. It is also hypothesized that the change from evergreen to deciduous trait occurred before colonizing the high latitudes and was the reason "Metasequoia" was dominant in the north.
https://en.wikipedia.org/wiki?curid=334634
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By 1945, the U.S. Army's Chemical Warfare Service developed chemical warfare rockets intended for the new M9 and M9A1 Bazookas. An M26 Gas Rocket was adapted to fire cyanogen chloride-filled warheads for these rocket launchers. As it was capable of penetrating the protective filter barriers in some gas masks, it was seen as an effective agent against Japanese forces (particularly those hiding in caves or bunkers) because their standard issue gas masks lacked the barriers that would provide protection against cyanogen chloride. The US added the weapon to its arsenal, and considered using it, along with hydrogen cyanide, as part of Operation Downfall, the planned invasion of Japan, but President Harry Truman decided against it, instead using the atomic bombs developed by the secret Manhattan Project. The CK rocket was never deployed or issued to combat personnel.
https://en.wikipedia.org/wiki?curid=1095275
539,238
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In order for any transformation to take place, the microstructure of the metal must be austenite structure. The exact boundaries of the austenite phase region depend on the chemistry of the alloy being heat treated. However, austenitizing temperatures are typically between 790 and 915°C (1455 to 1680°F). The amount of time spent at this temperature will vary with the alloy and process specifics for a through-hardened part. The best results are achieved when austenitization is long enough to produce a fully austenitic metal microstructure (there will still be graphite present in cast irons) with a consistent carbon content. In steels this may take only a few minutes after the austenitizing temperature has been reached throughout the part section, but in cast irons it takes longer. This is because carbon must diffuse out of the graphite until it has reached the equilibrium concentration dictated by the temperature and the phase diagram. This step may be done in many types of furnaces, in a high-temperature salt bath, or via direct flame or induction heating. Numerous patents describe specific methods and variations.
https://en.wikipedia.org/wiki?curid=17173535
1,304,121
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He studied at Amherst College for his Bachelor of Science Honours degree in biology, then at Columbia University for an M.Sc in Biology and a doctorate in zoology in 1921. Romer joined the department of geology and paleontology at the University of Chicago as an associate professor in 1923. He was an active researcher and teacher. His collecting program added important Paleozoic specimens to Chicago's Walker Museum of Paleontology. In 1934 he was appointed professor of biology at Harvard University. In 1946, he became director of the Harvard Museum of Comparative Zoology (MCZ). In 1954 Romer was awarded the Mary Clark Thompson Medal from the National Academy of Sciences. He was awarded the Academy's Daniel Giraud Elliot Medal in 1956. In 1961, Romer received the Golden Plate Award of the American Academy of Achievement.
https://en.wikipedia.org/wiki?curid=519648
1,512,825
2,023,151
Coinciding with the division change, the Lady Ice Lions received a significant boost in the effort to succeed in Division 1 in the form of four players cut from PSU's NCAA Division I team during the 2014 offseason: forwards Darby Kern, Cara Mendelson and Katie Murphy, along with defenseman Madison Smiddy. Mendelson, Murphy and Smiddy had spent their freshman years in 2011–12 as Lady Icers before joining the NCAA team for two seasons, while Kern was a year younger with no prior ACHA experience. A fifth NCAA cut, Jessica Desorcie, also joined the Women's Ice Hockey Club as an assistant coach. Numerous key players from the Division 2 seasons also remained, including Fisk, Schaffer, Saideh, Elia and Tonetti, while the regular incoming class was highlighted by Kelly Watson, Riley O'Connor, Claire Gauthier and Tarika Embar. Tonetti, despite being a senior, was also an addition in a sense, as she was finally able to move back to her natural goaltending position after two years playing forward in order to balance out the occasionally-wobbly roster count.
https://en.wikipedia.org/wiki?curid=51386378
2,021,987
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The fossil record of this family dates back to the Miocene epoch. Living bristlemouths were discovered by William Beebe in the early 1930s and described by L. S. Berg in 1958. The fish are mostly found in the Atlantic, Indian, and Pacific Oceans, although the species "Cyclothone microdon" may be found in Arctic waters. They have elongated bodies from in length. They have a number of green or red light-producing photophores aligned along the undersides of their heads or bodies. Their chief common name, bristlemouth, comes from their odd, equally sized, and bristle-like teeth. They are typically black in color which provides camouflage from predators in deep, dark waters. They mainly feed on zooplankton and small crustaceans due to their small size.
https://en.wikipedia.org/wiki?curid=845253
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1,455,640
Pure alexia exhibits some unexpected residual abilities despite the inability to read words. For instance, one patient had preserved calculation capabilities such as deciding which number was greater, and whether a number was odd or even with greater than chance probability. The study showed that the patient was also able to calculate simple arithmetic tasks such as addition, subtraction, and division, but not multiplication, even though the patient could not read the numbers. For example, the patient would be presented with "8 – 6", and he or she would read it as "five minus four", but still come up with the correct answer "two" with greater than chance accuracy. Pure alexia patients also seem to retain some residual semantic processing. They are able to perform better than chance when forced to make a lexical decision or make a semantic-categorisation decision. These subjects also performed better with nouns than functors, better with words that had high rather than low imageability, and performed poorly with suffixes. However, this may be due to right hemisphere input or residual left hemisphere input.
https://en.wikipedia.org/wiki?curid=11630765
1,454,820
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In water treatment plants, organic halides are adsorbed using GAC or PAC in agitated tanks. The loaded carbon is separated using a membrane made out of materials like polypropylene or cellulose nitrate. Measuring the AOX levels into and out of the treatment zone shows a drop in organic halide concentrations. Some processes use a two-step GAC filtration to remove AOX precursors, and thus reduce the amount of AOX in treated waters. A two step filtration process consists of two GAC filters in series. The first filter is loaded with exhausted GAC, while the second filter is loaded with fresh GAC. This set up is preferred for its increased efficiency and higher throughput capacity. The GAC is replaced cyclically and the extracted organic halide-carbon mixture is then sent for subsequent biological or chemical treatment such as ozonation to regenerate the GAC. Often, these chemical treatments, while effective, pose economical challenges to the treatment plants.
https://en.wikipedia.org/wiki?curid=51487091
1,254,660
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To use modern terminology, if "p" and "q" are natural numbers such that "p">"q" then ("p" − "q", 2"pq", "p" + "q") forms a Pythagorean triple. The triple is primitive, that is the three triangle sides have no common factor, if "p" and "q" are coprime and not both odd. Neugebauer and Sachs propose the tablet was generated by choosing "p" and "q" to be coprime regular numbers (but both may be odd—see Row 15) and computing "d" = "p" + "q", "s" = "p" − "q", and "l" = 2"pq" (so that "l" is also a regular number). For example, line 1 would be generated by setting "p" = 12 and "q" = 5. Buck and Robson both note that the presence of Column 1 is mysterious in this proposal, as it plays no role in the construction, and that the proposal does not explain why the rows of the table are ordered as they are, rather than, say, according to the value of formula_10 or formula_11, which, under this hypothesis, might have been listed on columns to the left in the broken-off portion of the tablet. Robson also argues that the proposal does not explain how the errors in the table could have plausibly arisen and is not in keeping with the mathematical culture of the time.
https://en.wikipedia.org/wiki?curid=2983547
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In May 2013, a group led by Hualan Chen, director of China's National Avian Influenza Reference Laboratory, published several experiments they had conducted at the BSL3+ laboratory of the Harbin Veterinary Research Institute, investigating what would happen if a 2009 H1N1 circulating in humans infected the same cell as an avian influenza H5N1. Importantly, the experiments had been conducted before a research pause on H5N1 experiments had been agreed upon by the greater virologist community. They used these experiments to determine that certain genes, if reassorted in such a dual-infection scenario in the wild, would allow transmission of the H5N1 virus more easily in mammals (notably guinea pigs as a model organism for rodent species), proving that certain agricultural scenarios carry the risk of allowing H5N1 to cross over into mammals. As in the Fouchier and Kawaoka experiments above, the viruses in this study were also significantly less lethal after the modification.
https://en.wikipedia.org/wiki?curid=66516195
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His reputation as an ophthalmologist extended throughout Europe and the USA largely as a result of the success of "Diseases of the Eye- a Practical Treatise for Students of Ophthalmology" which became a widely read textbook . The first (1889) and the second (1893) editions were both published in the United Kingdom and in the USA. Its success was because it was widely considered to be a comprehensive account of the state of knowledge of the speciality and also because of the many original observations which it contained. In addition he published two monographs which were widely acclaimed and used, "Subjective symptoms in Eye Disease (1886)" and "The Elements of" "Ophthalmoscope diagnosis (1891)." He later combined many of the elements of these earlier works into the practical textbook "Manual of practical ophthalmology." published in 1905 in the UK and the USA "." Berry published an early description of the rare facial dysostosis condition which was initially called Berry-Treacher Collins syndrome. The English ophthalmologist Edward Treacher Collins gave a fuller description in 1900 and the condition is now generally known as Treacher Collins syndrome.
https://en.wikipedia.org/wiki?curid=25154028
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There was a resurgence of interest in the "HCG diet" following promotion by Kevin Trudeau, who was banned from making HCG diet weight-loss claims by the U.S. Federal Trade Commission in 2008, and eventually jailed over such claims.<ref name="FTC 2008/10">Kevin Trudeau Banned from Infomercials For Three Years, Ordered to Pay More Than $5 Million for False Claims About Weight-Loss Book; "FTC v. Trudeau" (7th Cir., 2009) 579 F.3d 754 remanded (N.D.Ill., 2010) 708 F.Supp.2d 711, affirmed (7th Cir. 2011) 662 F.3d 947, certiorari denied (Oct. 9, 2012) _U.S._, 133 S.Ct. 426, 184 L.Ed.2d 257; and a ten-year prison sentence for violating a court order, "U.S. v. Trudeau" (N.D.Ill., Jan. 29, 2014) 2014 u.s.dist. LEXIS 10717, 2014 WL 321373. And the article, "The Curious Case of Kevin Trudeau, King Catch Me If You Can " by Catherine Bryant Bell, Mississippi Law Journal, vol. 79 page 1043 (summer 2010), http://heinonline.org/HOL/Page?handle=hein.journals/mislj79&div=44&g_sent=1&collection=journals#1053.</ref>
https://en.wikipedia.org/wiki?curid=300445
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The main cause of Wankel Diesel engine infeasibility is the shape of the combustion chamber, located in the rotary piston. It is elongated and convex, thus not allowing a high enough compression ratio (without too much heat loss), even in combination with a (solely crankshaft or exhaust gas driven) supercharger. This means that the engine is only functional if it is fed externally compressed air, as it requires more work to operate than it can produce. Also, designing a proper combustion chamber, correctly angled towards the injection nozzle to allow proper mixture formation, proved to be quite difficult; the EPA study proves that the Wankel Diesel engine's exhaust contains disproportionally high levels of carbon monoxide (CO) and hydrocarbons (HC), indicating incomplete combustion.
https://en.wikipedia.org/wiki?curid=59593680
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Northern Ireland provides a wide range of options for further and higher education through its universities, regional colleges (for further education), and other specialist colleges for teacher training and the agri-food sector. The Open University and regional colleges, in particular, enrol large numbers of adult learners. Many young people choose to travel to Great Britain to continue their education although this has, for many years, caused concern about a 'brain drain' effect and the difficulty in retaining skills and knowledge in the region's economy. The relatively low cost of living and higher quality of life in smaller and closer-knit communities, though, is an attraction for many students and graduates from Britain, the rest of Ireland and elsewhere.
https://en.wikipedia.org/wiki?curid=355737
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The experience that more than any other defined Munch's career was his reestablished connection with the islanders of Tristan da Cunha. In 1961, a volcanic eruption on the remote island forced evacuation of the entire population, never before exposed to modern life, to an abandoned Royal Air Force base in southern England. Munch quickly applied for research grants to visit the evacuees and to study their adaptation to modern European life. He found that most islanders were unhappy in their new homes and was relieved when the British government agreed to finance the resettlement of Tristan da Cunha in 1963, when the volcano was again dormant. More grants enabled Munch to visit the islanders on Tristan in 1964-1965 for additional research; a visit that resulted in lectures, books, and articles contributing to our understanding of anarchy, atomism, acculturation in social systems, and to our general knowledge of community and social values.
https://en.wikipedia.org/wiki?curid=11647873
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Gudeman brings post-modern cultural relativism to its logical conclusion. Generally speaking, however, culturalism can also be seen as an extension of the substantivist view, with a stronger emphasis on cultural constructivism, a more detailed account of local understandings and metaphors of economic concepts, and a greater focus on socio-cultural dynamics than the latter (cf. Hann, 2000). Culturalists tend to be both less taxonomic and more culturally relativistic in their descriptions while critically reflecting on the power relationship between the ethnographer (or 'modeller') and the subjects of his or her research. While substantivists generally focus on institutions as their unit of analysis, culturalists lean towards detailed and comprehensive analyses of particular local communities. Both views agree in rejecting the formalist assumption that all human behaviour can be explained in terms of rational decision-making and utility maximisation.
https://en.wikipedia.org/wiki?curid=418436
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The sequence of events leading to anoxic oceans may have been triggered by carbon dioxide emissions from the eruption of the Siberian Traps. In that scenario, warming from the enhanced greenhouse effect would reduce the solubility of oxygen in seawater, causing the concentration of oxygen to decline. Increased weathering of the continents due to warming and the acceleration of the water cycle would increase the riverine flux of phosphate to the ocean. The phosphate would have supported greater primary productivity in the surface oceans. The increase in organic matter production would have caused more organic matter to sink into the deep ocean, where its respiration would further decrease oxygen concentrations. Once anoxia became established, it would have been sustained by a positive feedback loop because deep water anoxia tends to increase the recycling efficiency of phosphate, leading to even higher productivity.
https://en.wikipedia.org/wiki?curid=24749
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With Billingham, he published a seminal paper in 1951 on grafting technique. Santa J. Ono, the American immunologist, has described the enduring impact of this paper to modern science. Based on this technique of grafting, Medawar's team devised a method to test Burnet's hypothesis. They extracted cells from young mouse embryos and injected them into another mouse of different strains. When the mouse developed into adult and skin grafting from that of the original strain was performed, there was no tissue rejection. Meaning that the mouse had tolerated the foreign tissue, which would normally be rejected. Their experimental proof of Burnet's hypothesis was first published in a brief article in "Nature" in 1953, followed by a series of papers, and a comprehensive description in "Philosophical Transactions of the Royal Society B" in 1956, giving the name "actively acquired tolerance".
https://en.wikipedia.org/wiki?curid=172002
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The scale of Birkeland's research enterprises was such that funding became an overwhelming obstacle. Recognizing that technological invention could bring wealth, he developed an electromagnetic cannon and, with some investors, formed a firearms company. The coil-gun worked, except the high muzzle velocities he predicted (600 m/s) were not produced. The most he could get from his largest machine was 100 m/s, corresponding to a disappointing projectile range of only 1 km. So he renamed the device an aerial torpedo and arranged a demonstration with the express aim of selling the company. At the demonstration, one of the coils shorted and produced a sensational inductive arc complete with noise, flame, and smoke. This was the first failure of any of the launchers that Birkeland had built. It could easily have been repaired and another demonstration organized.
https://en.wikipedia.org/wiki?curid=64146
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Miller continued his research until his death in 2007. As the knowledge on early atmosphere progressed, and techniques for chemical analyses advanced, he kept on refining the details and methods. He not only succeeded in synthesizing more and more varieties of amino acids, he also produced a wide variety of inorganic and organic compounds essential for cellular construction and metabolism. In support, a number of independent researchers also confirmed the range of chemical syntheses. With the most recent revelation that, unlike the original Miller's experimental hypothesis of strongly reducing condition, the primitive atmosphere could be quite neutral containing other gases in different proportions, Miller's last works, posthumously published in 2008, still succeeded in synthesizing an array of organic compounds using such condition.
https://en.wikipedia.org/wiki?curid=92419
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Following the end of the First World War, the F.2B Fighter was soon adopted by the RAF as its standard army cooperation machine. The type continued to operate in army cooperation and light bombing roles in the British Empire, in particular the Middle East and India. In line with this role, which led to its use in a hot climate, Bristol introduced models of the Fighter equipped with 'tropical' radiators and provision for desert equipment. There had also been considerations made into deploying the Fighter as a carrier-based aircraft, which led to an engineless airframe participating in immersion trials in November 1918 and an aircraft being used in deck landing tests, reportedly on board HMS Eagle.
https://en.wikipedia.org/wiki?curid=946746
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The Tiger Moth responds well to control inputs and is fairly easy to fly for a tail-dragger. Its big "parachute" wings are very forgiving, and it stalls at a speed as slow as 25 knots with power. Its stall and spin characteristics are benign. It has some adverse yaw and therefore requires rudder input during turns. The Tiger Moth exhibits the fundamental requirements of a training aircraft, in being "easy to fly, but difficult to fly well"; the aircraft's benign handling when within its limits make it easy for the novice to learn the basic skills of flight. At the same time techniques such as coordinated flight must be learnt and used effectively, and the aircraft will show up mishandling to an observant instructor or attentive pupil. As training progresses towards more advanced areas, especially aerobatics, the skill required on the part of a Tiger Moth pilot increases. The aircraft will not, like some training aircraft, "fly its way out of trouble" but will instead stall or spin if mishandled. However the stall and spin remain benign, again showing up deficient piloting without endangering the aircraft or the crew. These characteristics were invaluable to military operators, who must identify between pilots with the potential to go on to fly fighter aircraft, those more suited to lower-performance machines and those who must be relegated to non-pilot aircrew positions.
https://en.wikipedia.org/wiki?curid=528202
220,662
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During the latter half of the 19th century, physicists such as Rudolf Clausius, Peter Guthrie Tait, and Willard Gibbs worked to develop the concept of a thermodynamic system and the correlative energetic laws which govern its associated processes. The equilibrium state of a thermodynamic system is described by specifying its "state". The state of a thermodynamic system is specified by a number of extensive quantities, the most familiar of which are volume, internal energy, and the amount of each constituent particle (particle numbers). Extensive parameters are properties of the entire system, as contrasted with intensive parameters which can be defined at a single point, such as temperature and pressure. The extensive parameters (except entropy) are generally conserved in some way as long as the system is "insulated" to changes to that parameter from the outside. The truth of this statement for volume is trivial, for particles one might say that the total particle number of each atomic element is conserved. In the case of energy, the statement of the conservation of energy is known as the first law of thermodynamics.
https://en.wikipedia.org/wiki?curid=1515898
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Created on November 5, 1958, the Space Task Group was headed by Robert Gilruth. Originally it consisted of 45 people, including eight secretaries and "computers", the occupational title for women who ran calculations on mechanical adding machines. Of its 37 engineers, 27 were from Langley Research Center, and 10 had been assigned from Lewis Research Center in Cleveland, Ohio. Original members of the group included Charles Donlan, Gilruth's deputy; Max Faget, head of engineering; Chuck Mathews, head of flight operations; Chris Kraft, also in flight operations; and Glynn Lunney, who at 21 was the youngest member of the group. The head of the public affairs office was John "Shorty" Powers.
https://en.wikipedia.org/wiki?curid=7628698
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Also influential on the emerging discipline of psychology were debates surrounding the efficacy of Mesmerism (a precursor to hypnosis) and the value of phrenology. The former was developed in the 1770s by Austrian physician Franz Mesmer (1734–1815) who claimed to use the power of gravity, and later of "animal magnetism", to cure various physical and mental ills. As Mesmer and his treatment became increasingly fashionable in both Vienna and Paris, it also began to come under the scrutiny of suspicious officials. In 1784, an investigation was commissioned in Paris by King Louis XVI which included American ambassador Benjamin Franklin, chemist Antoine Lavoisier and physician Joseph-Ignace Guillotin (later the popularizer of the guillotine). They concluded that Mesmer's method was useless. Abbé Faria, an Indo-Portuguese priest, revived public attention in animal magnetism. Unlike Mesmer, Faria claimed that the effect was 'generated from within the mind’ by the power of expectancy and cooperation of the patient.
https://en.wikipedia.org/wiki?curid=1573230
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Gecko feet are the most famous reversible adhesion mechanism in nature. The anti-fouling ability of feet allows geckos to run on dusty ceilings and corners without the accumulation of dirt on their feet. In 2000, Autumn et al. revealed the origin of gecko’s strong adhesion by investigating the surface features of the toes under electron microscope. They observed a hierarchical morphology of each foot which is composed of millions of small hair called setae. Moreover, each setae is composed of a smaller hair, and each hair is tailed with a flat spatula and these spatulae are bonded by the van der Waals forces. This surface feature, regardless of the surface type (hydrophobic, hydrophilic, dry, wet, rough etc.), enables geckos to stick the surface. In addition to strong adhesion, the gecko foot has a unique self-cleaning property which does not require water as the lotus leaf.
https://en.wikipedia.org/wiki?curid=53941569
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The budding yeast, "Saccharomyces cerevisiae", is a model system for eukaryotic biology in which many of the fundamental elements of polarity development have been elucidated. Yeast cells share many features of cell polarity with other organisms, but feature fewer protein components. In yeast, polarity is biased to form at an inherited landmark, a patch of the protein Rsr1 in the case of budding, or a patch of Rax1 in mating projections. In the absence of polarity landmarks (i.e. in gene deletion mutants), cells can perform spontaneous symmetry breaking, in which the location of the polarity site is determined randomly. Spontaneous polarization still generates only a single bud site, which has been explained by positive feedback increasing polarity protein concentrations locally at the largest polarity patch while decreasing polarity proteins globally by depleting them. The master regulator of polarity in yeast is Cdc42, which is a member of the eukaryotic Ras-homologous Rho-family of GTPases, and a member of the super-family of small GTPases, which include Rop GTPases in plants and small GTPases in prokaryotes. For polarity sites to form, Cdc42 must be present and capable of cycling GTP, a process regulated by its guanine nucleotide exchange factor (GEF), Cdc24, and by its GTPase-activating proteins (GAPs). Cdc42 localization is further regulated by cell cycle queues, and a number of binding partners. A recent study to elucidate the connection between cell cycle timing and Cdc42 accumulation in the bud site uses optogenetics to control protein localization using light. During mating, these polarity sites can relocate. Mathematical modeling coupled with imaging experiments suggest the relocation is mediated by actin-driven vesicle delivery.
https://en.wikipedia.org/wiki?curid=21942008
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Additional genetic testing relating to pregnancy-associated malaria is currently being researched which involves looking at glucose-6-phosphate dehydrogenase (G6PD) which is an enzyme that is responsible for keeping red blood cells protected from being destroyed too soon by things such as foods and medications. The gene for this enzyme is found on the X chromosome which means that women in particular can have G6PD function that is normal, intermediate (which often shows up on lab tests as normal), and deficient. This gene is important in determining if certain antimalarial drugs such as Primaquine and Tafenoquine can be used since these antimalarial drugs are more likely to cause red blood cell hemolysis in women with a G6PD deficiency and worsen any anemia that comes from the malaria infection. Although these drugs would most likely be used after delivery for treatment of pregnancy-associated malaria, this genetic testing can help avoid inducing anemia in women more prone to red blood cell breakdown.
https://en.wikipedia.org/wiki?curid=31348010
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The larvae of the subfamilies Psychodinae, Sycoracinae and Horaiellinae live in aquatic to semi-terrestrial or sludge-based habitats, including bathroom sinks, where they feed on bacteria and can become problematic. The larvae of the most commonly encountered species are nearly transparent with a non-retractable black head and can sometimes be seen moving along the moist edges of crevices in shower stalls or bathtubs or submerged in toilet water. The larval form of the moth fly is usually between long, and is shaped like a long, thin, somewhat flattened cylinder. The body lacks prolegs, but the body segments are divided into a series of rings called "annuli" (singular is "annulus"). Some of these rings will have characteristic plates on the dorsal side. The larval thorax is not significantly larger than its abdomen, giving it a more "worm-like" appearance than that of most aquatic insect larvae.
https://en.wikipedia.org/wiki?curid=3293252
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Millisecond pulsars, which can be timed with high precision, have a stability comparable to atomic-clock-based time standards when averaged over decades. This also makes them very sensitive probes of their environments. For example, anything placed in orbit around them causes periodic Doppler shifts in their pulses' arrival times on Earth, which can then be analyzed to reveal the presence of the companion and, with enough data, provide precise measurements of the orbit and the object's mass. The technique is so sensitive that even objects as small as asteroids can be detected if they happen to orbit a millisecond pulsar. The first confirmed exoplanets, discovered several years before the first detections of exoplanets around "normal" solar-like stars, were found in orbit around a millisecond pulsar, PSR B1257+12. These planets remained, for many years, the only Earth-mass objects known outside of the Solar System. One of them, PSR B1257+12 D, has an even smaller mass, comparable to that of the Moon, and is still today the smallest-mass object known beyond the Solar System.
https://en.wikipedia.org/wiki?curid=1490987
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In the summer of 2007, the U.S. Library of Congress moved their audio, video and film restoration group to Culpeper, Virginia where the newly completed National Audio-Visual Conservation Center Packard Campus is sited. Gene DeAnna heads the Recorded Sound Section. With 3 million sound recordings and many more film and video works that include synchronized sound in the archive, the mission of the Sound Section is twofold: preserve the treasure of vintage sound recordings and increase public accessibility to the collection. One of the ways that access can be increased is through the diligent digitization of analog media. The Library has expressed interest in the Fadeyev/Haber 2D imaging method for quick digital archival of their vast collection of vinyl and shellac phonograph records. Audio restoration tasks will take place in parallel with the digitization effort. A massive multi-petabyte storage array is nearing completion; it will hold the large digital audio and moving image files.
https://en.wikipedia.org/wiki?curid=4039099
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In March 2014, the Council of Ministers of Higher Education and Scientific Research in the Arab World endorsed the draft "Arab Strategy for Science, Technology and Innovation" at its 14th congress in Riyadh, Saudi Arabia. The strategy has three main thrusts: academic training in science and engineering, scientific research and regional and international scientific co-operation. One of the strategy's key objectives is to involve the private sector more in regional and interdisciplinary collaboration, in order to add economic and development value to research and make better use of available expertise. Up to now, science, technology and innovation policies in Arab states have failed to catalyse knowledge production effectively or add value to products and services because they focus on developing research without taking the business community on board. There has also been a lot of talk about re-orienting the education system towards innovation and entrepreneurship but little action.
https://en.wikipedia.org/wiki?curid=25038241
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In March 2014, the Council of Ministers of Higher Education and Scientific Research in the Arab World endorsed the draft "Arab Strategy for Science, Technology and Innovation" at its 14th congress in Riyadh, Saudi Arabia. The strategy has three main thrusts: academic training in science and engineering, scientific research and regional and international scientific co-operation. One of the strategy's key objectives is to involve the private sector more in regional and interdisciplinary collaboration, in order to add economic and development value to research and make better use of available expertise. Up to now, science, technology and innovation policies in Arab states have failed to catalyse knowledge production effectively or add value to products and services because they focus on developing research without taking the business community on board. There has also been a lot of talk about re-orienting the education system towards innovation and entrepreneurship but little action.
https://en.wikipedia.org/wiki?curid=47911441
1,986,921