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1,424,447 | One adjustment necessary is to control for the type I error in the McDonald–Kreitman test, refer to the discussion of this in previous section "Sources of Error with the McDonald Kreitman Test." One method to avoid type I errors is to avoid using populations that have undergone a recent bottleneck, meaning they have re... | https://en.wikipedia.org/wiki?curid=30761750 | 1,423,645 |
1,535,806 | He is the winner of seven teaching awards at the University of Arizona and he has taught over 5000 students, mostly in introductory astronomy classes for non-science majors. He taught part of an astrobiology class in the 3D virtual world called Second Life, and more recently he has taught a massive open online course (... | https://en.wikipedia.org/wiki?curid=39139794 | 1,534,938 |
1,018,156 | The disease was first noted by the Swiss naturalist Charles Bonnet, who described the condition in 1760. He documented it in his 90-year-old grandfather who was nearly blind from cataracts in both eyes. After Bonnet’s grandfather received bilateral cataract surgery, his vision evolved from slightly better to complete d... | https://en.wikipedia.org/wiki?curid=576518 | 1,017,629 |
1,135,134 | Alkynes also undergo hydrohalogenation reactions. Depending on the exact substrate, alkyne hydrohalogenation can proceed though a concerted protonation/nucleophilic attack (Ad3) or stepwise by first protonating the alkyne to form a vinyl cation, followed by attack of HX/X to give the product (Ad2) ("see" electrophile "... | https://en.wikipedia.org/wiki?curid=1745989 | 1,134,541 |
632,265 | In 1996 David Kehoe and Arthur Grossman at the Carnegie Institution at Stanford University identified the proteins, in the filamentous cyanobacterium Fremyella diplosiphon called RcaE with similarly to plant phytochrome that controlled a red-green photoreversible response called chromatic acclimation and identified a g... | https://en.wikipedia.org/wiki?curid=652209 | 631,927 |
291,916 | Relative addresses are a form of manual memory segmentation, and share many of its advantages and disadvantages. A two-byte offset, containing a 16-bit, unsigned integer, can be used to provide relative addressing for up to 64 KiB (2 bytes) of a data structure. This can easily be extended to 128, 256 or 512 KiB if the ... | https://en.wikipedia.org/wiki?curid=459018 | 291,758 |
984,543 | Until the 1990s, virtually all AAV biology was studied using AAV serotype 2. However, AAV is highly prevalent in humans and other primates and several serotypes have been isolated from various tissue samples. Serotypes 2, 3, 5, and 6 were discovered in human cells, AAV serotypes 1, 4, and 7–11 in nonhuman primate sampl... | https://en.wikipedia.org/wiki?curid=1883421 | 984,029 |
1,189,861 | For mobile use the original coastal gun was too heavy, so a smaller version was developed as the 3-inch M1918. This weapon was based on the Driggs-Seabury 3-inch gun M1898, a smaller predecessor of the M1903. This weapon had a barrel 50 calibers long instead of 55 calibers, and a smaller breech with a different cartrid... | https://en.wikipedia.org/wiki?curid=4266050 | 1,189,229 |
2,451 | Along with her younger sister, Serena, Venus Williams was coached by her parents Oracene Price and Richard Williams. Turning professional in 1994, she reached her first major final at the 1997 US Open. In 2000 and 2001, Williams claimed the Wimbledon and US Open titles, as well as Olympic singles gold at the 2000 Sydne... | https://en.wikipedia.org/wiki?curid=167378 | 2,451 |
1,361,151 | The K scale is used as a complement validity indicator to the L (for "lie") scale, whose items were selected based on item content face validity and are more obviously focused on impression management. The K scale has been popular among clinical psychologists, and has been a useful tool for MMPI and MMPI-2 profile inte... | https://en.wikipedia.org/wiki?curid=3125942 | 1,360,398 |
233,817 | Appropriate penetration of the film can be assessed by faint visualization of the thoracic spines and lung markings behind the heart. The right diaphragm is usually higher than the left, with the liver being situated beneath it in the abdomen. The minor fissure can sometimes be seen on the right as a thin horizontal li... | https://en.wikipedia.org/wiki?curid=1502182 | 233,698 |
492,081 | During the solar cycle, as shown in the sequence of images at right, at times the Sun is almost X-ray dark, almost an X-ray variable. Betelgeuse, on the other hand, appears to be always X-ray dark. Hardly any X-rays are emitted by red giants. There is a rather abrupt onset of X-ray emission around spectral type A7-F0, ... | https://en.wikipedia.org/wiki?curid=44062 | 491,827 |
1,576,914 | If the carbon in freshwater is partly acquired from aged carbon, such as rocks, then the result will be a reduction in the / ratio in the water. For example, rivers that pass over limestone, which is mostly composed of calcium carbonate, will acquire carbonate ions. Similarly, groundwater can contain carbon derived fro... | https://en.wikipedia.org/wiki?curid=43455139 | 1,576,025 |
341,436 | Acorn began considering how to compete in this market and produced a new paper design named the Acorn Business Computer. They set themselves the goal of producing a machine with ten times the performance of the BBC Micro, but at the same price. This would outperform and underprice the PC. At the same time, the recent i... | https://en.wikipedia.org/wiki?curid=60558 | 341,255 |
1,600,657 | On 1 July 2020, on behalf of NOAA, NASA has awarded the Space Weather Follow On-Lagrange 1 (SWFO-L1) Solar Wind Plasma Sensor (SWiPS) contract to Southwest Research Institute (SwRI) in San Antonio, Texas. SwRI was awarded a contract with a total value of US$15.6 million. The period of performance is 76 months. SWFO-L1 ... | https://en.wikipedia.org/wiki?curid=62073057 | 1,599,756 |
660,608 | At Kazan University, Lobachevsky was influenced by professor Johann Christian Martin Bartels, a former teacher and friend of the German mathematician Carl Friedrich Gauss (1777-1855). Lobachevsky received a Master of Science in physics and mathematics in 1811. In 1814 he became a lecturer at Kazan University, in 1816 h... | https://en.wikipedia.org/wiki?curid=648527 | 660,263 |
1,758,164 | There was no clear favorite in the men's 3000 m steeplechase, as the collegiate yearly leader did not qualify and no scoring athletes returned from last year's final. Most expected the race to be tactical due to wet conditions, but the University of Houston's Brian Barraza gapped the field early, taking the race out at... | https://en.wikipedia.org/wiki?curid=57596294 | 1,757,171 |
327,338 | Although the occurrence of DCS is not easily predictable, many predisposing factors are known. They may be considered as either environmental or individual. Decompression sickness and arterial gas embolism in recreational diving are associated with certain demographic, environmental, and dive style factors. A statistic... | https://en.wikipedia.org/wiki?curid=61048 | 327,164 |
658,897 | Once a user is logged on successfully, access to his own EFS encrypted data requires no additional authentication, decryption happens transparently. Thus, any compromise of the user's password automatically leads to access to that data. Windows can store versions of user account passphrases with reversible encryption, ... | https://en.wikipedia.org/wiki?curid=628391 | 658,552 |
953,700 | Interest in pure mathematics that is separate from empirical study has been part of the experience of various civilizations, including that of the ancient Greeks, who "did mathematics for the beauty of it". The aesthetic pleasure that mathematical physicists tend to experience in Einstein's theory of general relativity... | https://en.wikipedia.org/wiki?curid=18974136 | 953,195 |
17,813 | Public debate in the United Kingdom continues over whether admissions processes at Oxford and Cambridge are entirely merit-based and fair, whether enough students from state schools are encouraged to apply to Cambridge, and whether these students are offered sufficient admission. In 2020–21, 71% of all successful appli... | https://en.wikipedia.org/wiki?curid=25978572 | 17,807 |
1,681,617 | Packraft and trail boat are colloquial terms for a small, portable inflatable boat designed for use in all bodies of water, including technical whitewater and ocean bays and fjords. A packraft is designed to be light enough to be carried for extended distances. Along with its propulsion system (collapsible paddles or l... | https://en.wikipedia.org/wiki?curid=10691764 | 1,680,674 |
2,232,243 | As a member of the Territorial Army, Anderson was instantly brought into service at the outbreak of the Second World War and joined the Royal Hampshire Regiment. He was transferred in 1941 to the Zuckerman Research Team looking at the effects of aerial bomb explosions. Termed a “military geologist” he worked alongside ... | https://en.wikipedia.org/wiki?curid=53404563 | 2,230,976 |
1,185,814 | Much of his later work related to reflection in practice and the concept of learning systems. The course of his career would cover three areas in this field: 1) the learning society; 2) professional learning and effectiveness; and, 3) the reflective practitioner. Together with Chris Argyris, Schön provided the foundati... | https://en.wikipedia.org/wiki?curid=1219295 | 1,185,185 |
1,224,887 | Following the addition of Brian Benoit to replace Fulton, The Dillinger Escape Plan released its debut full-length album "Calculating Infinity" in 1999. Jeff Wood played bass on the album's promotional tour, and was later replaced the following year by Liam Wilson. In 2001, Minakakis left the band and was not replaced ... | https://en.wikipedia.org/wiki?curid=14268967 | 1,224,227 |
839,378 | Stanley P. Lovell, deputy director for Research and Development of the Office of Strategic Services, reports in his book "Of Spies and Stratagems" that the Allies knew the Germans had quantities of Gas Blau available for use in the defense of the Atlantic Wall. The use of nerve gas on the Normandy beachhead would have ... | https://en.wikipedia.org/wiki?curid=60215761 | 838,929 |
327,868 | The documentary film "" (1988) attributes Monk's quirky behavior to mental illness. In the film, Monk's son says that his father sometimes did not recognize him, and he reports that Monk was hospitalized on several occasions owing to an unspecified mental illness that worsened in the late 1960s. No reports or diagnoses... | https://en.wikipedia.org/wiki?curid=84250 | 327,694 |
80,908 | Nearly three decades later, the Horten Ho 229 flying wing fighter-bomber, developed in Nazi Germany during the last years of World War II proved to have some stealth characteristics due to its lack of vertical surfaces (key characteristic of all stealth aircraft plus inherent feature of all flying wing aircraft like th... | https://en.wikipedia.org/wiki?curid=403883 | 80,875 |
1,804,125 | sSMCs' genes are clearly part of a cell's genotype, i.e. gene profile, but may not be activatable and therefore not alter an individual. In many cases, however, the genes in a sSMCs are active, over-expressed, and considered causes of the associated sSMC's disorder. sSMCs may form as a result of one or more of the foll... | https://en.wikipedia.org/wiki?curid=2018913 | 1,803,111 |
1,287,185 | Form perception is the recognition of visual elements of objects, specifically those to do with shapes, patterns and previously identified important characteristics. An object is perceived by the retina as a two-dimensional image,[1] but the image can vary for the same object in terms of the context with which it is vi... | https://en.wikipedia.org/wiki?curid=32197396 | 1,286,484 |
503,706 | In 2014, Dr Warner C. Greene and Dr Gilad Doitsh at the Gladstone Institutes identified pyroptosis as the predominant mechanism that causes the two signature pathogenic events in HIV infection––CD4 T-cell depletion and chronic inflammation. Identifying pyroptosis may provide novel therapeutic opportunities targeting ca... | https://en.wikipedia.org/wiki?curid=38900235 | 503,448 |
91,812 | Shepard's next assignment was to VF-193, a night fighter squadron flying the Banshee, that was based at Naval Air Station Moffett Field, California. The squadron was part of Commander James D. "Jig Dog" Ramage's Air Group 19. Naval aviators with experience in jet aircraft were still relatively rare, and Ramage specific... | https://en.wikipedia.org/wiki?curid=63727 | 91,772 |
1,170,662 | On April 15, 2013, the RIWI Corporation, led by researcher Neil Seeman of the University of Toronto released data on 7,016 Chinese “fresh” (i.e. non-panel based) Internet users – with a 24.08% response rate – over 20 hours. The level of contagion awareness was 31% in Beijing, 38% in Hangzhou, 33% in Nanjing, 40% in Sha... | https://en.wikipedia.org/wiki?curid=38969724 | 1,170,043 |
169,822 | The English-language neologism omics informally refers to a field of study in biology ending in "-omics", such as genomics, proteomics or metabolomics. The related suffix -ome is used to address the objects of study of such fields, such as the genome, proteome or metabolome respectively. The suffix "-ome" as used in mo... | https://en.wikipedia.org/wiki?curid=55170 | 169,732 |
1,943,666 | Clindicators can be designed on the basis of endogenously expressed fluorescent proteins such as Yellow fluorescent protein (YFP). An advantage of endogenously expressed probes over dye-based probes is their ability to achieve cell-type-specificity by the choice of Promoter (genetics) promotor. YFP based indicators are... | https://en.wikipedia.org/wiki?curid=30189546 | 1,942,554 |
166,722 | There are conflicting opinions on the number of federal crimes, but many have argued that there has been explosive growth and it has become overwhelming. In 1982, the U.S. Department of Justice could not come up with a number, but estimated 3,000 crimes in the United States Code. In 1998, the American Bar Association s... | https://en.wikipedia.org/wiki?curid=32211 | 166,636 |
681,914 | On November 3, 1933, the Nazi government demanded that professors begin their lectures by giving the Nazi salute. Köhler thought this was a violation of his own beliefs and told his students that he was unable to engage in such an act. His explanation was met with applause, from both Nazi sympathizers and rebels alike.... | https://en.wikipedia.org/wiki?curid=286151 | 681,558 |
1,932,796 | The binding of IL-8 to the receptor induces the following three main responses in neutrophils, all of which assist a neutrophil in developing molecular mechanisms to target and kill pathogens: shape and conformational change of the neutrophil (which allows for transendothelial migration of the cell), degranulation (cau... | https://en.wikipedia.org/wiki?curid=15669003 | 1,931,688 |
778,635 | By repeating this type of procedure Sanger was able to determine the sequences of the many peptides generated using different methods for the initial partial hydrolysis. These could then be assembled into the longer sequences to deduce the complete structure of insulin. Finally, because the A and B chains are physiolog... | https://en.wikipedia.org/wiki?curid=63349 | 778,218 |
1,428,022 | Nanostructured materials are gaining increased attention because of their potential to mitigate current electrode limitations. However, it is possible to use of vertically aligned multi-walled carbon nanotubes (VA-MWNTs) as the active electrode material in lithium-ion batteries. At low specific currents, these VA-MWNTs... | https://en.wikipedia.org/wiki?curid=51417988 | 1,427,218 |
1,161,805 | When computational models attempt to mimic human cognitive functioning, all the details of the function must be known for them to transfer and display properly through the models, allowing researchers to thoroughly understand and test an existing theory because no variables are vague and all variables are modifiable. C... | https://en.wikipedia.org/wiki?curid=1988689 | 1,161,189 |
883,552 | In February 2015 Volvo Cars announced its plans to lease 100 XC90 SUVs fitted with Drive Me Level 3 automation technology to residents of Gothenburg in 2017. The Drive Me XC90s will be equipped with Nvidia’s Drive PX 2 supercomputer, and will be driven autonomously in certain weather conditions and on one road that loo... | https://en.wikipedia.org/wiki?curid=44787757 | 883,088 |
427,845 | After graduating, Mifune was sent to a Tokyo preparatory school, anticipating entry into Waseda University. He immediately attempted to join the Kodokan. In those days, this required a personal interview with Kano, upon the recommendation of ranking judoka, and then signing a blood oath. Mifune did not know anyone at t... | https://en.wikipedia.org/wiki?curid=5275977 | 427,635 |
731,887 | In 2013, Anil Seth proposed that our subjective feeling states, otherwise known as emotions, are generated by predictive models that are actively built out of causal interoceptive appraisals. In relation to how we attribute internal states of others to causes, Sasha Ondobaka, James Kilner, and Karl Friston (2015) propo... | https://en.wikipedia.org/wiki?curid=53953041 | 731,500 |
1,255,896 | The sea otter, "Enhydra lutris", is a member of the Mustelidae that is fully aquatic. Sea otters are the smallest of the marine mammals, but they are also the most dexterous. Sea otters are known for their ability to use stones as anvils or hammers to facilitate access to hard-to-reach prey items. Furthermore, out of t... | https://en.wikipedia.org/wiki?curid=48861989 | 1,255,212 |
611,918 | The NKAP had asked Mikoyan to begin preliminary design work on a high-altitude interceptor in January 1944, but ordered two prototypes of an all-metal interceptor using the VRDK for testing in February and March 1945. The aircraft was to reach an altitude of in 4.5 minutes with full power and 5.5 minutes using the pist... | https://en.wikipedia.org/wiki?curid=304230 | 611,607 |
862,180 | Very rare causes of awareness include drug tolerance, or a tolerance induced by the interaction of other drugs. Some patients may be more resistant to the effects of anesthetics than others; factors such as younger age, obesity, tobacco smoking, or long-term use of certain drugs (alcohol, opiates, or amphetamines) may ... | https://en.wikipedia.org/wiki?curid=667636 | 861,720 |
259,243 | Several forms of interference have been discussed by theorists. One of the oldest ideas is that new items simply replace older ones in working memory. Another form of interference is retrieval competition. For example, when the task is to remember a list of 7 words in their order, we need to start recall with the first... | https://en.wikipedia.org/wiki?curid=33912 | 259,109 |
329,025 | Narratively, the player takes the role of Peter, a hacker aboard a satellite orbiting the Moon, forced by his employer the Kasma Corporation to figure out what happened at the Pytheas Moonbase. Peter does this by running through simulations, in which he takes the place of one of five known survivors of the attack. The ... | https://en.wikipedia.org/wiki?curid=11718979 | 328,851 |
1,175,772 | About 2–3 Ma, in the Pleistocene, continental ice sheets expanded from the polar regions of the globe to cover lower latitudes far north of the region, starting a series of cold glacial periods that were interrupted by warmer interglacial periods. Snowmelt from alpine glaciers on the nearby Sierra Nevada during glacial... | https://en.wikipedia.org/wiki?curid=1134149 | 1,175,150 |
1,275,476 | Jaynes (1985, 2003, "et passim") discussed the concept of probability. According to the MaxEnt viewpoint, the probabilities in statistical mechanics are determined jointly by two factors: by respectively specified particular models for the underlying state space (e.g. Liouvillian phase space); and by respectively speci... | https://en.wikipedia.org/wiki?curid=3015758 | 1,274,784 |
250,395 | The civilian stations Salyut 6 and Salyut 7 were built with two docking ports, which allowed a second crew to visit, bringing a new spacecraft with them; the Soyuz ferry could spend 90 days in space, at which point it needed to be replaced by a fresh Soyuz spacecraft. This allowed for a crew to man the station continua... | https://en.wikipedia.org/wiki?curid=50896 | 250,263 |
327,296 | Project SCRAM is a policing effort by the Halton Regional Police Service to register and help consumers understand the complex issues of privacy and safety that confront households when dealing with installations of home security systems. "The SCRAM program enables community members to voluntarily identify and register... | https://en.wikipedia.org/wiki?curid=87179 | 327,122 |
1,492,265 | Until reliable high-temperature printed circuit boards were developed, turret board construction was considered the best available technology. Currently, the use of turret boards is limited to hand-wired vacuum tube electronics (be it commercial or hobby), often as an attempt to replicate a classic design or design app... | https://en.wikipedia.org/wiki?curid=8179028 | 1,491,426 |
180,293 | As early as 1973 and before the first interstellar detection, chemical models of the interstellar medium (the first corresponding to a dense cloud) predicted that hydronium was an abundant molecular ion and that it played an important role in ion-neutral chemistry. However, before an astronomical search could be underw... | https://en.wikipedia.org/wiki?curid=49281 | 180,199 |
1,597,441 | Even when the recession ends, the metamorphosis of economic form shall continue, accelerate and expand. Less and less we shall be able to tell the difference. Pressures for increased productivity growth rates, declining employment and workforce participation, as well as budget cuts shall grow unabated. Due to massive a... | https://en.wikipedia.org/wiki?curid=40624374 | 1,596,542 |
554,825 | At Cambridge University the ancient professorship of pure mathematics is denominated by the Lucasian, and is the chair that had been occupied by Isaac Newton. Around 1860, certain funds bequeathed by Lady Sadleir to the university, having become useless for their original purpose, were employed to establish another pro... | https://en.wikipedia.org/wiki?curid=311034 | 554,536 |
859,214 | Spatial visualization is especially important in science and technology. For example, an astronomer must visually imagine the structures of a solar system, and the path of the bodies within it. An engineer must visually imagine the motions of the parts of a machine or building that they are assigned to work with. Chemi... | https://en.wikipedia.org/wiki?curid=49045837 | 858,756 |
470,015 | "B. rupestris" is deciduous. Trees in their native habitat are typically leafless between September and December; the timing, duration and extent of leaf drop may be affected by extremes of rainfall or drought. Sometimes trees shed leaves from only some branches. On every tree, the leaves vary in shape, ranging from na... | https://en.wikipedia.org/wiki?curid=6693638 | 469,779 |
77,305 | The use of ETFs has also evolved over time, as shown by regular observations of investment professionals’ practices in Europe. EDHEC surveys show an increasing propagation of ETF adoption over the years, especially for traditional asset classes. While ETFs are now used across a wide spectrum of asset classes, in 2019 t... | https://en.wikipedia.org/wiki?curid=538170 | 77,276 |
875,342 | By the time Model C began operations, information collected from previous machines was making it clear that it would not be able to produce large-scale fusion. Ion transport across the magnetic field lines was much higher than classical theory suggested. Greatly increased magnetic fields of the later machines did littl... | https://en.wikipedia.org/wiki?curid=29591 | 874,880 |
470,584 | Treatment in fibrous dysplasia is mainly palliative, and is focused on managing fractures and preventing deformity. There are no medications capable of altering the disease course. Intravenous bisphosphonates may be helpful for treatment of bone pain, but there is no clear evidence that they strengthen bone lesions or ... | https://en.wikipedia.org/wiki?curid=1617101 | 470,348 |
1,419,954 | Mathews directed the Acoustical and Behavioral Research Center at Bell Laboratories from 1962 to 1985, which carried out research in speech communication, visual communication, human memory and learning, programmed instruction, analysis of subjective opinions, physical acoustics, and industrial robotics. From 1974 to 1... | https://en.wikipedia.org/wiki?curid=479801 | 1,419,155 |
862,268 | In 1957, at the end of its run of flight tests, the NB-36H was decommissioned and scrapped at Carswell. The nuclear reactor was removed. With Cold War tensions increasing in the late 1950s, the US government pushed for development of a heavy bomber with jet engines. Parallel programs of nuclear and conventional aircraf... | https://en.wikipedia.org/wiki?curid=31810031 | 861,808 |
337,391 | In 1991, professor and "New York Times" writer Jay Dolan critiqued "Generations" for not talking more about class, race, and sex, to which Neil Howe replied that they "are probably generalizations not even as effective as a generation to say something about how people think and behave. One of the things to understand i... | https://en.wikipedia.org/wiki?curid=28937240 | 337,212 |
226,914 | Mach also became well known for his philosophy, developed in close interplay with his science. Mach defended a type of phenomenalism recognizing only sensations as real. This position seemed incompatible with the view of atoms and molecules as external, mind-independent things. He famously declared, after an 1897 lectu... | https://en.wikipedia.org/wiki?curid=55285 | 226,798 |
709,325 | In parallel to the rise and fall of Hilbert's program, the foundations of structural proof theory were being founded. Jan Łukasiewicz suggested in 1926 that one could improve on Hilbert systems as a basis for the axiomatic presentation of logic if one allowed the drawing of conclusions from assumptions in the inference... | https://en.wikipedia.org/wiki?curid=183478 | 708,955 |
794,188 | The primary military purposes are to allow improved command and control of forces through improved location awareness, and to facilitate accurate targeting of smart bombs, cruise missiles, or other munitions, and spoofing or jamming location data to civilian navigation receivers during wartime. The satellites also carr... | https://en.wikipedia.org/wiki?curid=2380807 | 793,763 |
1,406,282 | The Flemish sculpture together with that of Germanic countries developed with a realism that was appreciated in all the ornamental details, where the sculptural work was presented almost as a work of goldsmithing that was applied in the great altars made of wood. Also in Spain, the Gothic-Flemish influence together wit... | https://en.wikipedia.org/wiki?curid=70869604 | 1,405,492 |
557,953 | Many people are able to perceive polarization of light. Haidinger's brushes may be seen as a yellowish horizontal bar or bow-tie shape (with "fuzzy" ends, hence the name "brush") visible in the center of the visual field against the blue sky viewed while facing away from the sun, or on any bright background. It typical... | https://en.wikipedia.org/wiki?curid=49298 | 557,664 |
959,634 | During the military occupation of Germany and the postwar rebuilding of Europe, the American Army Corps of Engineers, the newly established French government, and the British Ministry of Defence engaged in one of the most prolonged and successful mine-clearing operations throughout Western Europe. France deployed a var... | https://en.wikipedia.org/wiki?curid=1186910 | 959,126 |
372,868 | The NMDA receptor is ionotropic, meaning it is a protein which allows the passage of ions through the cell membrane. The NMDA receptor is so named because the agonist molecule "N"-methyl--aspartate (NMDA) binds selectively to it, and not to other glutamate receptors. Activation of NMDA receptors results in the opening ... | https://en.wikipedia.org/wiki?curid=374338 | 372,673 |
1,859,362 | Terrestrial leaf litter, wood inputs and deposition of pollen are important organic matter sources that augment benthic invertebrate productivity. In particular, these terrestrial subsidies are vital for detritivores and shredders and control their population sizes. Benthic invertebrate communities respond swiftly to c... | https://en.wikipedia.org/wiki?curid=41384413 | 1,858,294 |
1,434,658 | In an conventional CCC experiment the biphasic solvent system is pre-equilibrated before the instrument is filled with the stationary phase and equilibrated with the mobile phase. An ion-exchange mode has been created by modifying both of the phases after pre-equilibration. Generally, an ionic displacer (or eluter) is ... | https://en.wikipedia.org/wiki?curid=30862402 | 1,433,854 |
185,962 | On the basis of this fact the "Alanine World" hypothesis was proposed. This hypothesis explains the evolutionary choice of amino acids in the repertoire of the genetic code from a chemical point of view. In this model the selection of monomers (i.e. amino acids) for ribosomal protein synthesis is rather limited to thos... | https://en.wikipedia.org/wiki?curid=63539 | 185,865 |
823,898 | Nevertheless, the inter-atomic distances derived from the observed NOE can often help to confirm the three-dimensional structure of a molecule. In this application, the NOE differs from the application of J-coupling in that the NOE occurs through space, not through chemical bonds. Thus, atoms that are in close proximit... | https://en.wikipedia.org/wiki?curid=335612 | 823,455 |
1,806,655 | Besides the English tradition, German, Italian and Irish immigrants also had a major impact on the American brass band tradition. Forty-two professional German musicians, for example, formed the Seventh Regiment Band, one of the most famous brass bands during the 1850s and the only exclusively regimental band of the pe... | https://en.wikipedia.org/wiki?curid=2581433 | 1,805,637 |
1,159,296 | William Penney directed bomb design from Fort Halstead. In 1951 his design group moved to a new site at Aldermaston in Berkshire. The first British atomic bomb was successfully tested in Operation Hurricane, during which it was detonated on board the frigate anchored off the Monte Bello Islands in Australia on 3 Octobe... | https://en.wikipedia.org/wiki?curid=52573493 | 1,158,681 |
1,043,049 | On 12 December 1846, Bain, who was then living in Edinburgh, patented a chemical telegraph. He had seen that the Morse and other telegraphs then in use were comparatively slow, due to the mechanical inertia of their moving parts, and realized that the signal current could be used to make a readable mark on a moving pap... | https://en.wikipedia.org/wiki?curid=1341253 | 1,042,505 |
888,692 | Molecular clock users have developed workaround solutions using a number of statistical approaches including maximum likelihood techniques and later Bayesian modeling. In particular, models that take into account rate variation across lineages have been proposed in order to obtain better estimates of divergence times. ... | https://en.wikipedia.org/wiki?curid=250001 | 888,224 |
295,822 | The Starshot concept envisions launching a "mothership" carrying about a thousand tiny spacecraft (on the scale of centimeters) to a high-altitude Earth orbit for deployment. A phased array of ground-based lasers would then focus a light beam on the crafts' sails to accelerate them one by one to the target speed within... | https://en.wikipedia.org/wiki?curid=50147624 | 295,662 |
954,153 | Biosensors employing nucleic acid based receptors can be either based on complementary base pairing interactions referred to as genosensors or specific nucleic acid based antibody mimics (aptamers) as aptasensors. In the former, the recognition process is based on the principle of complementary base pairing, adenine:th... | https://en.wikipedia.org/wiki?curid=480700 | 953,648 |
621,833 | Roberts' linear tactics concept had an early critic in the younger historian Geoffrey Parker, who asked why the supposedly outdated Spanish tercios defeated the Swedish linear formations at the battle of Nördlingen in 1634. Parker instead suggested that the key development was the appearance of the trace italienne fort... | https://en.wikipedia.org/wiki?curid=1008992 | 621,501 |
196,759 | In 1807 the imperial government opened a competition for a hydraulic machine to replace the original Marly machine (located in Marly-le-Roi) that delivered water to the Palace of Versailles from the Seine river. The machine was built in Bougival in 1684, from where it pumped water a distance of one kilometer and raised... | https://en.wikipedia.org/wiki?curid=143000 | 196,659 |
1,413,363 | The true quadratic dependency of drag on velocity was experimentally proven independently by Edme Mariotte and Christiaan Huygens, both members of the Paris Academy of Sciences, in the late 17th century. Sir Isaac Newton later became the first person to theoretically derive this quadratic dependence of air resistance i... | https://en.wikipedia.org/wiki?curid=40119871 | 1,412,567 |
1,087,142 | In 1974, at the age of twenty, Drinfeld announced a proof of the Langlands conjectures for GL over a global field of positive characteristic. In the course of proving the conjectures, Drinfeld introduced a new class of objects that he called "elliptic modules" (now known as Drinfeld modules). Later, in 1983, Drinfeld p... | https://en.wikipedia.org/wiki?curid=1053747 | 1,086,583 |
1,463,478 | In 1984, New York City hired physicist Alan J. Friedman to help with the museum's transition from a focus on science fiction-type exhibits that predicted the future, to relevance to everyday lives of ordinary citizens. At the time Friedman was appointed, the museum was basically an empty shell, having "an inch of water... | https://en.wikipedia.org/wiki?curid=1460266 | 1,462,655 |
245,479 | "Vikram" began its descent at 20:08:03 UTC, 6 September 2019 and was scheduled to land on the Moon at around 20:23 UTC. The descent and soft-landing were to be performed by the on-board computers on "Vikram", with mission control unable to make corrections. The initial descent was considered within mission parameters, ... | https://en.wikipedia.org/wiki?curid=19884971 | 245,352 |
123,672 | There have been attempts at creating information models for older, pre-existing facilities. Approaches include referencing key metrics such as the Facility Condition Index (FCI), or using 3D laser-scanning surveys and photogrammetry techniques (separately or in combination) or digitizing traditional building surveying ... | https://en.wikipedia.org/wiki?curid=3978080 | 123,621 |
1,411,477 | Other sources of groundwater contamination included: radioactive waste dumps on the territory of “exclusion zone”; cooling water reservoirs connected with aquifer; initial radioactive fallout which took place in first hours after the accident; and forest fires that led to accelerated spread of contaminated particles on... | https://en.wikipedia.org/wiki?curid=59803219 | 1,410,684 |
1,404,917 | On a visionary level, the concept of technoscience comprises a number of social, literary, artistic and material technologies from western cultures in the third millennium. This is undertaken in order to focus on the interplay of hitherto separated areas and to question traditional boundary-drawing: this concerns the b... | https://en.wikipedia.org/wiki?curid=1439193 | 1,404,127 |
1,082,015 | The reduction of the surface long-wave radiative flux drives the greenhouse effect. Greenhouse gases, such as methane (CH), nitrous oxide (NO), water vapor (HO) and carbon dioxide (CO), absorb certain wavelengths of OLR, preventing the thermal radiation from reaching space, adding heat to the atmosphere. Some of this t... | https://en.wikipedia.org/wiki?curid=6864370 | 1,081,459 |
1,091,697 | Drunk or not, Glazunov may have neither understood nor been totally committed to the symphony, as it was a composition in a newer, more modern idiom and greater length (approximately 45 minutes) than he might have expected. Nor was he apparently sympathetic to Rachmaninoff's music on the whole, commenting on another oc... | https://en.wikipedia.org/wiki?curid=2539421 | 1,091,137 |
1,205,722 | Hertz was concerned for his safety and, like his fellow Nobel laureate James Franck, was looking to move to the USA or any other place outside Germany. So he made a pact with three colleagues: Manfred von Ardenne, director of his private laboratory "Forschungslaboratorium für Elektronenphysik", Peter Adolf Thiessen, or... | https://en.wikipedia.org/wiki?curid=345776 | 1,205,077 |
1,298,282 | In April 2020 the company entered into a long-term partnership with University Hospital Basel's Liechti Lab, gaining rights to more than ten years of the lab's data related to LSD, MDMA, and other psychedelic substances. The development of a novel compound designed to shorten the duration or stop an LSD experience that... | https://en.wikipedia.org/wiki?curid=67846684 | 1,297,569 |
2,114,600 | Mg-Zn-Ca based metallic glasses are a relatively new group of amorphous metals, possessing commercial and technical advantages over early compositions. Gu and co-workers produced the first Mg-Zn-Ca BMG in 2005, reporting high glass forming ability, high strength and most importantly exceptional plasticity. This lanthan... | https://en.wikipedia.org/wiki?curid=31382667 | 2,113,385 |
434,620 | In March 2012, the plant's initial 40-year operating license was scheduled to expire; in March 2011, the Nuclear Regulatory Commission (NRC) extended its license for another 20 years. Vermont Yankee's continued operations were complicated by the Vermont state legislature's enactment of a law providing the state legisla... | https://en.wikipedia.org/wiki?curid=519753 | 434,406 |
392,291 | Carthaginian citizens served in their army only if there was a direct threat to the city. In most circumstances Carthage recruited foreigners to make up its army. Many would be from North Africa which provided several types of fighters including: close-order infantry equipped with large shields, helmets, short swords a... | https://en.wikipedia.org/wiki?curid=11427 | 392,096 |
324,031 | For physical fitness activity to benefit an individual, the exertion must trigger a sufficient amount of stimuli. Exercise with the correct amount of intensity, duration, and frequency can produce a significant amount of improvement. The person may overall feel better, but the physical effects on the human body take we... | https://en.wikipedia.org/wiki?curid=432986 | 323,859 |
2,221,479 | CSMT had partnership agreements for scientific collaboration and students exchange with universities in Europe, Asia and Australia.As of 2012, the college hosted more than 1000 students enrolled in twenty-eight undergraduate and seven graduate programs. The programs offer a range of degree plans from certificates and a... | https://en.wikipedia.org/wiki?curid=36920585 | 2,220,217 |
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