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649,219 | In 2014, Gilead announced it would seek generic licensing agreements with manufacturers to produce sofosbuvir in 91 developing countries, which contained 54% of the world's HCV-infected population. Gilead also said it would sell a name brand version of the product in India for $300 per course of treatment, approximatel... | https://en.wikipedia.org/wiki?curid=33832492 | 648,878 |
1,305,970 | RAGE (receptor for advanced glycation endproducts), also called AGER, is a 35 kilodalton transmembrane receptor of the immunoglobulin super family which was first characterized in 1992 by Neeper "et al." Its name comes from its ability to bind advanced glycation endproducts (AGE), which include chiefly glycoproteins, t... | https://en.wikipedia.org/wiki?curid=4992635 | 1,305,254 |
2,015,886 | High-intensity laser facilities offer prospects for directly measuring previously unobserved processes in QED, such as vacuum birefringence, photon-photon scattering and, still some way in the future, Schwinger pair production. Furthermore, `light-shining-through-walls' experiments can probe the low energy frontier of ... | https://en.wikipedia.org/wiki?curid=43699175 | 2,014,725 |
521,808 | Abt regained the lead temporarily for one lap when the field made pit stops. Bird later reclaimed the position with Vergne second. Swift work from Sarrazin's crew enabled him to gain the most places and move into fourth while Heidfeld fell to eighth. Di Grassi drove cautiously in his attempt to find space for a pass on... | https://en.wikipedia.org/wiki?curid=45532368 | 521,536 |
2,177,303 | Humans are strongly motivated to always predict and explain others behaviors. Social decision-making is made difficult because of the uncertainty of the other person’s behavior. Humans believe they are good at predicting other people, but it is also easy for that person to act differently or create their own actions fo... | https://en.wikipedia.org/wiki?curid=38180529 | 2,176,059 |
1,840,060 | The MZUSP has one of the largest natural-history collections in Latin America, with over 8.5 million preserved specimens of vertebrates (amphibians, mammals, birds, fish and reptiles) and invertebrates (cnidarians, insects, crustaceans, arachnids, myriapods, annelids, mollusks and other marine groups). Each collection ... | https://en.wikipedia.org/wiki?curid=36329115 | 1,839,008 |
1,174,082 | Early theoretical studies that depended on frontier orbital analysis established that Lewis acid catalysis operates via lowering of the dienophile's LUMO energy. Recent studies, however, have shown that this rationale behind Lewis acid-catalyzed Diels-Alder reactions is incorrect. It is found that Lewis acids accelerat... | https://en.wikipedia.org/wiki?curid=37264695 | 1,173,460 |
1,933,322 | This has led to multiple clinical trials that have validated the CURATE.AI platform. This AI platform has realized best-in-class medicines for population-wide administration, as well as the unprecedented ability to actionably personalize treatment for the entire duration of care on a patient-specific basis. Dr. Ho's ex... | https://en.wikipedia.org/wiki?curid=13833438 | 1,932,214 |
12,490 | By the end of the month, Asimov completed a second story, "Stowaway". Campbell rejected it on July 22 but—in "the nicest possible letter you could imagine"—encouraged him to continue writing, promising that Asimov might sell his work after another year and a dozen stories of practice. On October 21, 1938, he sold the t... | https://en.wikipedia.org/wiki?curid=14573 | 12,485 |
238,302 | Technetium-99 is produced by the nuclear fission of both uranium-235 and plutonium-239. It is therefore present in radioactive waste and in the nuclear fallout of fission bomb explosions. Its decay, measured in becquerels per amount of spent fuel, is the dominant contributor to nuclear waste radioactivity after about 1... | https://en.wikipedia.org/wiki?curid=30041 | 238,182 |
1,283,251 | From the start, the field deferred to Sebastián Martos, marked by Evan Jager, in turn marked by his teammate Hillary Bor. After a slow 2 and a half laps, Lamecha Girma moved up to the point. He too did not push the pace, so defending champion Conseslus Kipruto came forward. Still nobody wanted too push, the pack was pa... | https://en.wikipedia.org/wiki?curid=71265659 | 1,282,553 |
1,478,957 | After experimenting with new ideas in his home workshop, Hornby began making toys for his sons in 1899 with pieces he cut from sheet metal. He built models of bridges, trucks and cranes, although the pieces they were made from were not interchangeable. The breakthrough came when Hornby realised that if he could make se... | https://en.wikipedia.org/wiki?curid=977784 | 1,478,124 |
758,140 | Bates provides undergraduate instruction in the humanities, social sciences, natural sciences, and engineering and offers joint undergraduate programs with Columbia University, Dartmouth College, and Washington University in St. Louis, among others. A baccalaureate college, the undergraduate program requires all studen... | https://en.wikipedia.org/wiki?curid=319763 | 757,735 |
1,940,441 | In addition, the reflection phase of incident light is part of the AMC and HIS tool box. The phase of the reflected electric field has normal incidence the same phase of the electric field impinging at the interface of the reflecting surface. The variation of the reflection phase is continuous between +180◦ to −180◦ re... | https://en.wikipedia.org/wiki?curid=24631368 | 1,939,331 |
424,832 | The closest the Confederacy came to seriously attempting to equip colored soldiers in the army proper came in the last few weeks of the war. The Confederate Congress narrowly passed a bill allowing slaves to join the army. The bill did not offer or guarantee an end to their servitude as an incentive to enlist, and only... | https://en.wikipedia.org/wiki?curid=15799614 | 424,624 |
1,161,689 | The winter of 1906–07 was the coldest in Alberta's history and was exacerbated by a shortage of coal. One cause of this shortage was the strained relationship between coal miners and mine operators in the province. At the beginning of April 1907, the Canada West Coal and Coke Company locked out the miners from its mine... | https://en.wikipedia.org/wiki?curid=233760 | 1,161,073 |
613,067 | If the controller were to background garbage collect all of the spare blocks before it was absolutely necessary, new data written from the host could be written without having to move any data in advance, letting the performance operate at its peak speed. The trade-off is that some of those blocks of data are actually ... | https://en.wikipedia.org/wiki?curid=27560356 | 612,756 |
1,593,010 | Government funding has included a $55 million grant from New York State to support genomic medicine. In 2016 it received a $40 million grant from the National Human Genome Research Institute to establish a Center for Common Disease Genomics, and is leading a collaborative, large-scale genomic sequencing program focused... | https://en.wikipedia.org/wiki?curid=52344551 | 1,592,113 |
1,864,722 | There are actually two engagement times to consider in an electromagnetic coupling. The first one is the time it takes for a coil to develop a magnetic field, strong enough to pull in an armature. Within this, there are two factors to consider. The first one is the amount of ampere turns in a coil, which will determine... | https://en.wikipedia.org/wiki?curid=34274639 | 1,863,650 |
877,073 | After returning to Vienna he became an assistant to Max von Gruber at the Hygienic Institute. In his studies he concentrated on the mechanism of immunity and the nature of antibodies. From November 1897 to 1908 Landsteiner was an assistant at the pathological-anatomical institute of the University of Vienna under Anton... | https://en.wikipedia.org/wiki?curid=18945023 | 876,611 |
1,227,225 | Scolecodonts ("worm jaws" in Latin) are tiny jaws of polychaete annelids of the order Eunicida - a diverse and abundant group of worms which has been inhabiting different marine environments in the past 500 million years. Composed of highly resistant organic substance, the scolecodonts are frequently found as fossils f... | https://en.wikipedia.org/wiki?curid=1209622 | 1,226,564 |
231,430 | That is, being on the surface of the Earth is equivalent to being inside a spaceship (far from any sources of gravity) that is being accelerated by its engines. The direction or vector of acceleration equivalence on the surface of the earth is "up" or directly opposite the center of the planet while the vector of accel... | https://en.wikipedia.org/wiki?curid=857235 | 231,311 |
2,024,410 | The Dodd Galleries are dedicated to understanding and promoting contemporary art as a tool and catalyst for education. The Galleries consist of five exhibition spaces that act as laboratories and testing grounds for innovation located among our classrooms and studios. Committed to the idea of art-as-research, the galle... | https://en.wikipedia.org/wiki?curid=3973836 | 2,023,246 |
226,387 | A research team from the Botanical Garden and Department of Experimental and Social Sciences Education of the Faculty of Teacher Training of the University of Valencia warned in 2021 about the risk of pseudoscience in relation with myths or beliefs about the influence of the moon on agriculture. The findings of this sc... | https://en.wikipedia.org/wiki?curid=445231 | 226,271 |
197,624 | Although this chemical process had not been properly described before Pasteur's work, people had been using microbial lactic acid fermentation for food production much earlier. Chemical analysis of archeological finds show that milk fermentation uses predate the historical period; its first applications were probably a... | https://en.wikipedia.org/wiki?curid=200201 | 197,522 |
107,321 | The Antonov An-2 was designed to meet a 1940s Soviet Ministry of Forestry requirement for a replacement for the much lighter, largely wooden-airframed Polikarpov Po-2, which was used in large numbers in both agricultural and utility roles. Antonov designed a large single bay biplane of all-metal construction, with an e... | https://en.wikipedia.org/wiki?curid=702782 | 107,276 |
48,189 | A system-on-a-chip (SoC or SOC) is an integrated circuit in which all the components needed for a computer or other system are included on a single chip. The design of such a device can be complex and costly, and whilst performance benefits can be had from integrating all needed components on one die, the cost of licen... | https://en.wikipedia.org/wiki?curid=15150 | 48,169 |
273,619 | Robert Thorndike was asked to take over after Merrill's retirement. With the help of Elizabeth Hagen and Jerome Sattler, Thorndike produced the fourth edition of the Stanford–Binet Intelligence Scale in 1986. This edition covers the ages two through twenty-three and has some considerable changes compared to its predece... | https://en.wikipedia.org/wiki?curid=239041 | 273,471 |
9,304 | The Akkadian Empire dates to c. 2234–2154 BC (middle chronology). The Eastern Semitic Akkadian language is first attested in proper names of the kings of Kish c. 2800 BC, preserved in later king lists. There are texts written entirely in Old Akkadian dating from c. 2500 BC. Use of Old Akkadian was at its peak during th... | https://en.wikipedia.org/wiki?curid=50521 | 9,300 |
1,297,426 | Ferranti's Mark 23 was an X band design originally designed for the modified Fairey Delta 2 proposed for the Ministry of Supply's Operational Requirement F.155 for a modern interceptor aircraft. Work on F.155 ended with the infamous 1957 Defence White Paper, but by this time the interim English Electric Lightning desig... | https://en.wikipedia.org/wiki?curid=44128965 | 1,296,715 |
1,387,376 | The amount of power radiated by a loop antenna is proportional to , where is the current in the loop and is the area enclosed, To radiate practical power at ELF frequencies, the loop has to carry a current of hundreds of amperes and enclose an area of at least several square miles. Christofilos found that the lower the... | https://en.wikipedia.org/wiki?curid=9920139 | 1,386,609 |
1,483,142 | All electrified interfaces induce an organized charge distribution near the surface known as the electrical double layer. In pores of nanometer dimensions the electrical double layer may completely span the width of the nanopore, resulting in dramatic changes in the composition of the fluid and the related properties o... | https://en.wikipedia.org/wiki?curid=10172238 | 1,482,306 |
1,057,327 | Another key difference between cacti and "Euphorbiaceae" is origin and wild distribution. Cacti, including Astrophytum, are predominately found on the American continents, with a great variety in South America and Mexico. Though they are diverse, and widespread globally, the majority of "Euphorbia" succulents are found... | https://en.wikipedia.org/wiki?curid=9727478 | 1,056,778 |
858,460 | At 18:24, "Agincourt" opened fire on a German battlecruiser with her main guns. Shortly afterwards her six-inch guns followed suit as German destroyers made torpedo attacks on the British battleships to cover the turn to the south of the High Seas Fleet. "Agincourt" successfully evaded two torpedoes, although another s... | https://en.wikipedia.org/wiki?curid=872892 | 858,002 |
1,269,971 | In quantum computing, more specifically in superconducting quantum computing, flux qubits (also known as persistent current qubits) are micrometer sized loops of superconducting metal that is interrupted by a number of Josephson junctions. These devices function as quantum bits. The flux qubit was first proposed by Ter... | https://en.wikipedia.org/wiki?curid=5260042 | 1,269,280 |
1,016,116 | Compared to previous high-end 3D game accelerators, such as 3dfx Voodoo3 3500 and Nvidia RIVA TNT2 Ultra, GeForce provided up to a 50% or greater improvement in frame rate in some games (ones specifically written to take advantage of the hardware T&L) when coupled with a very-low-budget CPU. The later release and wides... | https://en.wikipedia.org/wiki?curid=148744 | 1,015,593 |
1,233,088 | A series of improvements were made for the next test on 8 July 1960 to create an engine known as Kiwi A Prime. The fuel elements were extruded into cylinders and coated with niobium carbide () to resist corrosion. Six were stacked end-to-end and then placed in the seven holes in the graphite modules to create long fuel... | https://en.wikipedia.org/wiki?curid=23821416 | 1,232,425 |
935,005 | Besides, unique and irreplaceable products enable companies to sell their products at higher prices. Because of the uniqueness of the product, companies do not worry too much about consumers switching to other products. However, the specific price setting should also follow the demand curve of the commodity. Suppose th... | https://en.wikipedia.org/wiki?curid=216660 | 934,511 |
819,679 | During this time, the United States confronted the prospect of war with Germany and the question of preparedness was raised. Engineering societies responded to this crisis by offering technical services to the Federal government such as the Naval Consulting Board of 1915 and the Council of National Defense of 1916. On ... | https://en.wikipedia.org/wiki?curid=5521184 | 819,238 |
62,253 | Around the beginning of the 20th century, general dissatisfaction with the emphasis on revivalist architecture and elaborate decoration gave rise to many new lines of thought that served as precursors to Modern architecture. Notable among these is the Deutscher Werkbund, formed in 1907 to produce better quality machine... | https://en.wikipedia.org/wiki?curid=21296224 | 62,228 |
181,301 | The main difficulty in selecting child nodes is maintaining some balance between the "exploitation" of deep variants after moves with high average win rate and the "exploration" of moves with few simulations. The first formula for balancing exploitation and exploration in games, called UCT ("Upper Confidence Bound" 1 "... | https://en.wikipedia.org/wiki?curid=40528449 | 181,207 |
526,421 | In different tumor subtypes, cells within the tumor population exhibit functional heterogeneity and tumors are formed from cells with various proliferative and differentiation capacities.<ref name="2/1"></ref> This functional heterogeneity among cancer cells has led to the creation of multiple propagation models to acc... | https://en.wikipedia.org/wiki?curid=2448941 | 526,148 |
38,244 | Before the research of Marshall and Warren, German scientists found spiral-shaped bacteria in the lining of the human stomach in 1875, but they were unable to culture them, and the results were eventually forgotten. The Italian researcher Giulio Bizzozero described similarly shaped bacteria living in the acidic environ... | https://en.wikipedia.org/wiki?curid=199665 | 38,230 |
2,130,396 | From 2008 to 2014 he was the principal investigator (PI) for the Baryon Oscillation Spectroscopic Survey (BOSS) project on the Sloan Telescope, at Apache Point, NM. This project was part of the Sloan Digital Sky Survey and created a three-dimensional map of 1.5 million galaxies. These galaxy maps are used to study the ... | https://en.wikipedia.org/wiki?curid=63659133 | 2,129,172 |
195,371 | Tracheotomy consists of making an incision on the front of the neck and opening a direct airway through an incision in the trachea. The resulting opening can serve independently as an airway or as a site for a tracheostomy tube to be inserted; this tube allows a person to breathe without the use of his nose or mouth. T... | https://en.wikipedia.org/wiki?curid=146396 | 195,271 |
1,271,187 | Calthemite straw stalactites precipitated (deposited) from hyperalkaline leachate have the potential to grow up to ≈200 times faster than normal cave speleothems precipitated from near neutral pH solution. One calthemite soda straw has been recorded as growing 2 mm per day over several consecutive days, when the leacha... | https://en.wikipedia.org/wiki?curid=52502945 | 1,270,496 |
141,733 | In 1865 English amateur astronomer William Huggins used his visual spectroscopy method to examine the nebula showing it, like other nebulae he had examined, was made up of "luminous gas". On September 30, 1880 Henry Draper used the new dry plate photographic process with an 11-inch (28 cm) refracting telescope to make ... | https://en.wikipedia.org/wiki?curid=177174 | 141,675 |
490,919 | Many states also hold invitational tournaments. These competitions serve as "practice rounds" for qualifying tournaments, and are hosted by individual middle schools, high schools and/or colleges. Invitationals occur most commonly in January or February, although there have been some as early as October or as late as A... | https://en.wikipedia.org/wiki?curid=665503 | 490,665 |
680,956 | Typical materials for ATR crystals include germanium, KRS-5 and zinc selenide, while silicon is ideal for use in the Far-IR region of the electromagnetic spectrum. The excellent mechanical properties of diamond make it an ideal material for ATR, particularly when studying very hard solids, although the broad diamond ph... | https://en.wikipedia.org/wiki?curid=5398131 | 680,601 |
2,745 | This led to outrage by the scientific community and Teller's virtual expulsion from academic science. Ernest Lawrence refused to testify on the grounds that he was suffering from an attack of ulcerative colitis, but an interview transcript in which he condemned Oppenheimer was presented as evidence in his absence. Grov... | https://en.wikipedia.org/wiki?curid=39034 | 2,745 |
1,409,838 | Answering this need, there are proposals for "active metamaterials" which can proactively control the proportion of transmission and reflection components of the source (EM) radiation. Strategies include illuminating the structure with laser light, varying an external static magnetic field where the current does not va... | https://en.wikipedia.org/wiki?curid=24386708 | 1,409,046 |
1,075,142 | In a paper published by Ye and colleagues in 2011, melanopsin was utilized to create an optogenetic synthetic transcription device that was tested in a therapeutic setting to produce Fc-glucagon-like peptide 1 (Fc-GLP-1), a fusion protein that helps control blood glucose levels in mammals with Type II Diabetes. The res... | https://en.wikipedia.org/wiki?curid=1110766 | 1,074,588 |
1,502,379 | In some transitions a number of atoms occupying crystallographic positions that were originally equivalent will move away slightly from their ideal positions according to a certain pattern. This pattern or repeat motif may span multiple unit cells. The cause of this phenomenon is the small changes in chemical bonding t... | https://en.wikipedia.org/wiki?curid=23251878 | 1,501,533 |
1,525,887 | During the early 1990s, linguist Donald Ringe, with computer scientists Luay Nakhleh and Tandy Warnow, statistician Steven N. Evans and others, began collaborating on research in quantitative comparative linguistic projects. They later founded the CHPL project, the goals of which include: "producing and maintaining rea... | https://en.wikipedia.org/wiki?curid=21312140 | 1,525,025 |
982,379 | In North America and Europe, it is estimated that three to five percent of adults have ADHD. Of those adults with ADHD, an estimated 10% of those have received a formal diagnosis. It has been estimated that 5% of the global population has ADHD (including cases not yet diagnosed). In the context of the World Health Orga... | https://en.wikipedia.org/wiki?curid=1673370 | 981,867 |
1,262,015 | Finally, since the gravitational potential is linked to the wave-function in the picture of the Schrödinger–Newton equation, the wave-function must be interpreted as a real object. Therefore, at least in principle, it becomes a measurable quantity. Making use of the nonlocal nature of entangled quantum systems, this co... | https://en.wikipedia.org/wiki?curid=1905371 | 1,261,328 |
519,737 | From time to time, Draper Laboratory hosts free exhibitions and events open to the public, which are presented in special semi-public spaces at the front of the central atrium space in the main Duffy Building. For example, in 2019 Draper presented "Hack the Moon", a celebration of the 50th anniversary of the first Apol... | https://en.wikipedia.org/wiki?curid=445258 | 519,468 |
726,599 | Admissions Office considers a student's GPA to be a very important academic factor, with a very high emphasis on an applicant's letters of recommendation, application essays, the rigor of academic record, and high school rank. In terms of non-academic materials as of 2022, Olin ranks extracurricular activities, the int... | https://en.wikipedia.org/wiki?curid=199627 | 726,217 |
939,324 | Since we started with over half the atoms in the spin-down state, this initially drives the system towards a 50/50 mixture, so the entropy is increasing, corresponding to a positive temperature. However, at some point, more than half of the spins are in the spin-up position. In this case, adding additional energy reduc... | https://en.wikipedia.org/wiki?curid=362728 | 938,823 |
627,477 | The tiny parasitic fly "Ormia ochracea" has become a model organism in sound localization experiments because of its unique ear. The animal is too small for the time difference of sound arriving at the two ears to be calculated in the usual way, yet it can determine the direction of sound sources with exquisite precisi... | https://en.wikipedia.org/wiki?curid=1021754 | 627,143 |
292,993 | Conventional c-Si solar cells, normally wired in series, are encapsulated in a solar module to protect them from the weather. The module consists of a tempered glass as cover, a soft and flexible encapsulant, a rear backsheet made of a weathering and fire-resistant material and an aluminium frame around the outer edge.... | https://en.wikipedia.org/wiki?curid=15677755 | 292,835 |
1,839,112 | Beginning in 1916, Espenschied worked with Herman Affel and other colleagues on a carrier system from Baltimore to Pittsburgh. This work led to Espenschied and Affel creating the first modern coaxial cable. Their invention paved the way for television transmission. The cable advanced long distance telephone service, ma... | https://en.wikipedia.org/wiki?curid=38493727 | 1,838,060 |
13,017 | In Syria, Colonel Rafik Halawi, the Druze commander of an infantry brigade that had collapsed during the Israeli breakthrough, was executed before the war even ended. He was given a quick hearing and sentenced to death; his execution was immediate. Military historian Zeev Schiff referred to him as Syria's "sacrificial ... | https://en.wikipedia.org/wiki?curid=34276 | 13,012 |
547,570 | More recently, a third generation of DNA sequencers was introduced. The sequencing methods applied by these sequencers do not require DNA amplification (polymerase chain reaction – PCR), which speeds up the sample preparation before sequencing and reduces errors. In addition, sequencing data is collected from the react... | https://en.wikipedia.org/wiki?curid=127511 | 547,283 |
1,127,416 | The history of early conservation has not yet been written, and early conservators recorded little of their work. Consequently, modern conservators are responsible for recording the previous conservation work they find when evaluating objects. As early as 750 B.C., Old Testament prophets Isaiah and Jeremiah advised on ... | https://en.wikipedia.org/wiki?curid=42491910 | 1,126,839 |
1,580,770 | The structure of the expression above follows standard principles of the probability theory: a summation is taken over alternatives, m, and various pieces of evidence, n, are multiplied. This expression is not necessarily a probability, but it has a probabilistic structure. If learning is successful, it approximates pr... | https://en.wikipedia.org/wiki?curid=19208664 | 1,579,880 |
763,149 | Whatever their particular culture, the Gallic and Germanic tribes generally proved themselves to be tough opponents, racking up several victories over their enemies. Some historians show that they sometimes used massed fighting in tightly packed phalanx-type formations with overlapping shields, and employed shield cove... | https://en.wikipedia.org/wiki?curid=30855309 | 762,740 |
744,164 | Alvan Feinstein's publication of "Clinical Judgment" in 1967 focused attention on the role of clinical reasoning and identified biases that can affect it. In 1972, Archie Cochrane published "Effectiveness and Efficiency", which described the lack of controlled trials supporting many practices that had previously been a... | https://en.wikipedia.org/wiki?curid=10013 | 743,770 |
1,149,695 | In January 2008, British Antarctic Survey (BAS) scientists reported that 2,200 years ago a volcano erupted under the Antarctic ice sheet. This was the biggest Antarctic eruption in the last 10,000 years. The volcano is situated in the Hudson Mountains, close to Pine Island Glacier. The eruption spread a layer of volcan... | https://en.wikipedia.org/wiki?curid=2815852 | 1,149,088 |
1,480,956 | He was awarded two major awards from the Ecological Society of America, the Mercer Award given to a young scientist in recognition of an outstanding paper in ecology in 1966, and the Eminent Ecologist Award for "outstanding contributions to the science of Ecology" in 1999. He also received the Kenneth Boulding Memorial... | https://en.wikipedia.org/wiki?curid=1411849 | 1,480,122 |
1,023,890 | The Preparatory Meeting to the UN Ocean Conference convened in New York, US, in February 2017, to discuss the implementation of Sustainable Development Goal 14. International law, as reflected in the UN Convention on the Law of the Sea (UNCLOS), stressed the need to include governance instruments to consider "anthropog... | https://en.wikipedia.org/wiki?curid=64523160 | 1,023,357 |
242,600 | To provide a black start, some power stations have small diesel generators, normally called the "black start diesel generator" (BSDG), which can be used to start larger generators (of several megawatts capacity), which in turn can be used to start the main power station generators. Generating plants using steam turbine... | https://en.wikipedia.org/wiki?curid=20344155 | 242,473 |
1,004,984 | Some regions of chromatin are very densely packed with fibers that display a condition comparable to that of the chromosome at mitosis. Heterochromatin is generally clonally inherited; when a cell divides, the two daughter cells typically contain heterochromatin within the same regions of DNA, resulting in epigenetic i... | https://en.wikipedia.org/wiki?curid=53983 | 1,004,466 |
1,125,010 | Brazil signed the Kyoto Protocol on April 29, 1998 and ratified it on August 23, 2002. To date, Brazil has 347 clean development mechanism (CDM) projects, which account for 7.3% of the total projects worldwide. Estimated projections by the United Nations Environment Programme (UNEP) show that by 2012, Brazil will have ... | https://en.wikipedia.org/wiki?curid=30916131 | 1,124,435 |
243,127 | From the late 1970s Wilson was actively involved in the global conservation of biodiversity, contributing and promoting research. In 1984 he published "Biophilia", a work that explored the evolutionary and psychological basis of humanity's attraction to the natural environment. This work introduced the word biophilia w... | https://en.wikipedia.org/wiki?curid=10313 | 243,000 |
376,852 | Logical positivism is commonly portrayed as taking the extreme position that scientific language should never refer to anything unobservable—even the seemingly core notions of causality, mechanism, and principles—but that is an exaggeration. Talk of such unobservables could be allowed as metaphorical—direct observation... | https://en.wikipedia.org/wiki?curid=37010 | 376,657 |
710,313 | China's semiconductor industry has, despite extensive governmental support, had many problems, such as innovative new designs. This may be due to factors such as poorly guided state and local government support for soon outdated technologies and geographically scattered efforts, lacking engineering education, and poor ... | https://en.wikipedia.org/wiki?curid=277914 | 709,942 |
1,458,985 | Since the late 1990s pioneering work of Luigi Luca Cavalli-Sforza and others, scientists have developed techniques that attempt to use genetic markers to indicate the ethnic background and history of individual people. The data developed by these mainstream scientists tell us that the Native Americans have very distinc... | https://en.wikipedia.org/wiki?curid=4874267 | 1,458,164 |
3,446 | Thomas Edison began his career as a news butcher, selling newspapers, candy and vegetables on the trains running from Port Huron to Detroit. He turned a $50-a-week profit by age 13, most of which went to buying equipment for electrical and chemical experiments. At age 15, in 1862, he saved 3-year-old Jimmie MacKenzie f... | https://en.wikipedia.org/wiki?curid=29778 | 3,446 |
292,910 | The uncrewed orbital flight test launched on December 20, 2019, but after deployment, an 11-hour offset in the mission clock of Starliner caused the spacecraft to compute that "it was in an orbital insertion burn", when it was not. This caused the attitude control thrusters to consume more fuel than planned, precluding... | https://en.wikipedia.org/wiki?curid=24068195 | 292,752 |
1,407,575 | Macrocyclization is a recurrent challenge for process chemists, and large pharmaceutical companies have necessarily developed creative strategies to overcome these inherent limitations. An interesting case study in this area involves the development of novel NS3 protease inhibitors to treat Hepatitis C patients by scie... | https://en.wikipedia.org/wiki?curid=41264758 | 1,406,785 |
68,056 | Despite the embargo, five MiG-23MFs that had been delivered prior to the outbreak of the war were rushed into service in the latter half of 1981. Attempting to replicate the success of the Mirage F1s that shot down two F-14 Tomcats on 15 November 1981, the pilots of Iraqi MiG-23 interceptor units started trying to snea... | https://en.wikipedia.org/wiki?curid=220186 | 68,030 |
1,395,606 | Management efforts in the United States began after "R. microplus" was deemed responsible for an estimated $63 billion in damages during the early 19th century. A control campaign began in 1906 and by 1943 it was considered complete, having eradicated most of the tick population other than a small region along the Sout... | https://en.wikipedia.org/wiki?curid=23596026 | 1,394,835 |
979,085 | Thiazides may be used to treat the symptoms of Dent's disease, an X-linked genetic condition that results in electrolyte imbalance with repeated episodes of kidney stones. A case study of two brothers with the condition, two years of treatment with hydrochlorothiazide reduced the incidence of kidney stones and improved... | https://en.wikipedia.org/wiki?curid=1179748 | 978,574 |
1,964,625 | Nanowires are artificial nano- or micro-sized “needles” that can provide high-fidelity electrophysiological recordings if used as microscopic electrodes for neuronal recordings. Nanowires are an attractive as they are highly functional structures that offer unique electronic properties that are affected by biological/c... | https://en.wikipedia.org/wiki?curid=67633513 | 1,963,497 |
1,970,363 | Explanations of linguistic expression of complex concepts have been linked to spreading activation models. When an individual identifies a lexical concept through vision or hearing, the corresponding node in that individual's cognitive network is said to activate. This makes it easier for lexical concepts linked to the... | https://en.wikipedia.org/wiki?curid=42415226 | 1,969,229 |
1,442,609 | The Weyl curvature hypothesis, which arises in the application of Albert Einstein's general theory of relativity to physical cosmology, was introduced by the British mathematician and theoretical physicist Roger Penrose in an article in 1979 in an attempt to provide explanations for two of the most fundamental issues i... | https://en.wikipedia.org/wiki?curid=3238937 | 1,441,796 |
1,290,877 | The rate of transcription for SWI/SNF and HDAC complexes seem to be regulated by the "INI1" gene. The SWI/SNF complex plays a role in chromatin remodeling. AT/RT is the first pediatric brain tumor for which a candidate tumor suppressor gene has been identified. A mutation or deletion in the "INI1/hSNF5" gene occurs in ... | https://en.wikipedia.org/wiki?curid=11200557 | 1,290,167 |
792,423 | Some force fields include explicit models for polarizability, where a particle's effective charge can be influenced by electrostatic interactions with its neighbors. Core-shell models are common, which consist of a positively charged core particle, representing the polarizable atom, and a negatively charged particle at... | https://en.wikipedia.org/wiki?curid=2916615 | 791,998 |
762,302 | Seaborg was a member of the professional chemistry fraternity Alpha Chi Sigma. As a graduate student in the 1930s Seaborg performed wet chemistry research for his advisor Gilbert Newton Lewis, and published three papers with him on the theory of acids and bases. Seaborg studied the text "Applied Radiochemistry" by Otto... | https://en.wikipedia.org/wiki?curid=13120 | 761,894 |
1,995,216 | Both ECs and adipocytes have been suggested to influence HSC activity in the bone marrow. Studies using antibody-mediated disruption of the VEGF receptors on ECs correlated with poor engraftment of donor cells. HUVECs, or endothelial cells isolated from umbilical veins, that were programmed via viral gene manipulation ... | https://en.wikipedia.org/wiki?curid=42606579 | 1,994,073 |
761,322 | The dedication and ground-breaking ceremony was held, but interrupted by protesters on October 7, 2014. The project became the focal point of escalating political conflict, police arrests and continued litigation over the proper use of conservation lands. Native Hawaiian cultural practice and religious rights became ce... | https://en.wikipedia.org/wiki?curid=4266335 | 760,915 |
1,949,633 | Shortly after its release, in 2005, Donald M. Hassler reviewed "The Greenwood Encyclopedia of Science Fiction and Fantasy" for "Extrapolation". He praised the aesthetics of the work, noting that the set is "beautifully bound in boards that look like pulp magazine covers". He found the volumes "useful and fun" but also ... | https://en.wikipedia.org/wiki?curid=68248898 | 1,948,512 |
2,026,481 | Genetic disruption of the Kcne3 gene in mice impairs intestinal cyclic AMP-stimulated chloride secretion via disruption of intestinal KCNQ1-KCNE3 channels that are important for regulating the chloride current. KCNE3 also performs a similar function in mouse tracheal epithelium. Kcne3 deletion in mice also predisposes ... | https://en.wikipedia.org/wiki?curid=14798297 | 2,025,314 |
56,863 | Filming began at Pinewood Toronto Studios in Toronto, Canada, on November 2, 2020, under the working title "Mill Street". Production was previously expected to take place from July 2020 to January 2021, filming back-to-back with a potential fifth season, but these plans were delayed by the COVID-19 pandemic. Kurtzman s... | https://en.wikipedia.org/wiki?curid=63388083 | 56,839 |
81,590 | Compared with the first two groups of astronauts, the third group of fourteen astronauts, which included Collins, was younger, with an average age of 31—the first two groups had an average age of 34.5 and 32.5 at their time of selection—and was better educated, with an average of 5.6 years of tertiary education; but th... | https://en.wikipedia.org/wiki?curid=97666 | 81,557 |
1,643,806 | Walton had been regarded as "avant garde" in his youth, but by 1957, when he was in his mid-fifties, he was seen as a composer in the romantic tradition, and some thought him old-fashioned by comparison with his younger English contemporary Benjamin Britten. After his only full-length opera, "Troilus and Cressida" (195... | https://en.wikipedia.org/wiki?curid=27425622 | 1,642,879 |
2,030,761 | The Cold War acted as a catalyst for progress in polar meteorology. Balloon instruments along the northern borders of the US and Canada were used for atmospheric profiling. North America’s air defenses often used instruments carried on balloons to profile the Arctic. Nuclear submarines, which the United States used as ... | https://en.wikipedia.org/wiki?curid=13305099 | 2,029,593 |
719,661 | The opening movement begins quietly with a march figure, but quickly moves to a more lyrical melody interspersed with a fanfare in the winds. The music grows abruptly in volume, with the violins taking up the principal melody over the march theme, which is now played by the brass. This uplifting theme transitions to a ... | https://en.wikipedia.org/wiki?curid=1444234 | 719,281 |
1,187,153 | One interesting, less common use of the MIPS architecture is in massive processor count supercomputers. Silicon Graphics (SGI) refocused its business from desktop graphics workstations to the high-performance computing market in the early 1990s. The success of the company's first foray into server systems, the Challeng... | https://en.wikipedia.org/wiki?curid=53839062 | 1,186,522 |
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