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Ataxia–telangiectasia like disorder (ATLD) is an extremely rare condition, caused by mutation in the hMre11 gene, that could be considered in the differential diagnosis of A–T. Patients with ATLD are very similar to those with A–T in showing a progressive cerebellar ataxia, hypersensitivity to ionizing radiation and genomic instability. Those rare individuals with ATLD who are well described differ from those with A–T by the absence of telangiectasia, normal immunoglobulin levels, a later onset, and a slower progression of the symptoms. Because of its rarity, it is not yet known whether or not ATLD carries an increased risk to develop cancer. Because those mutations of Mre11 that severely impair the MRE11 protein are incompatible with life, individuals with ATLD all have some partial function of the Mre11 protein, and hence likely all have their own levels of disease severity.
https://en.wikipedia.org/wiki?curid=1058672
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E-3,4-Q is a potent nucleophile, and will readily react with electrophilic DNA. This yields the formation of the DNA adducts 4-OHE-1-N7Gua and 4-OHE-1-N3Ade via a Michael addition. Destabilization of the glycosyl bond between the nitrogenous base and ribose sugar creates apurinic sites as the unstable adducts are lost from DNA. 4-OHE-1-N7Gua has a relatively slow depurination half-life of approx. 3 hours, allowing enough time for base excision repair mechanisms to correct the change. However, 4-OHE-1-N3Ade exhibits instantaneous depurination, leading to error-prone repair and the induction of mutations. Indeed, E-3,4-Q has been shown to cause A-to-G mutations in the gene coding for H¬-ras, ras being vital to the correct regulation of the cellular response to growth factors. Though 2- and 4-OHE have similar redox potentials and thus similar redox cycling activity, the greater carcinogenic capacity of 4-OHE can be attributed to its increased reactivity with DNA.
https://en.wikipedia.org/wiki?curid=54242243
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In the mid 1960s, the Japan Air Self-Defense Force (JASDF) commenced studies into an advanced jet trainer which could also be modified to serve in the ground attack and anti-shipping roles. After considering license production of the T-38 Talon and SEPECAT Jaguar, Japan decided to develop its own trainer, the supersonic Mitsubishi T-2, this first flying on 20 July 1971. Cost over-runs in the T-2 program led to the proposed single seat attack version almost being abandoned, but the cancellation of the Kawasaki P-XL, the planned replacement for Japan's Kawasaki P-2J maritime patrol aircraft freed-up funds, while making it important to keep Japan's aviation industry employed, and contracts were awarded for the development of the attack version as the FS-T2kai in 1973.
https://en.wikipedia.org/wiki?curid=2050929
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The predominantly aqueous electrolyte is composed of zinc bromide salt dissolved in water. During charge, metallic zinc is plated from the electrolyte solution onto the negative electrode (carbon felt in older designs, titanium mesh in modern) surfaces in the cell stacks. Bromide is converted to bromine at the positive electrode surface, to be stored in a safe, chemically complexed organic phase in the electrolyte tank. Older ZBRFB cells used polymer membranes (microporous polymers, Nafion etc.) More recent designs use no membrane. The battery stack is typically made of carbon-filled plastic bipolar plates (e.g. 60 cells), and is enclosed into a high-density polyethylene (HDPE) container.
https://en.wikipedia.org/wiki?curid=4673289
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Level 1 is a cab signalling system that can be superimposed on the existing signalling system, leaving the fixed signalling system (national signalling and track-release system) in place. Eurobalise radio beacons pick up signal aspects from the trackside signals via signal adapters and telegram coders ("Lineside Electronics Unit" – LEU) and transmit them to the vehicle as a "movement authority" together with route data at fixed points. The on-board computer continuously monitors and calculates the maximum speed and the "braking curve" from these data. Because of the spot transmission of data, the train must travel over the Eurobalise beacon to obtain the next "movement authority". In order for a stopped train to be able to move (when the train is not stopped exactly over a balise), there are optical signals that show permission to proceed. With the installation of additional Eurobalises (""infill balises"") or a "EuroLoop" between the distant signal and main signal, the new proceed aspect is transmitted continuously. The EuroLoop is an extension of the Eurobalise over a particular distance that basically allows data to be transmitted continuously to the vehicle over cables emitting electromagnetic waves. A radio version of the EuroLoop is also possible.
https://en.wikipedia.org/wiki?curid=2214121
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To develop a deeper understanding of the lifecycle of EV batteries, it is important to analyze the emission associated with different phases. Using NMC cylindrical cells as an example, Ciez and Whitacre found that around 9 kg COe kg battery"" is emitted during raw materials pre-processing and battery manufacturing under the US average electricity grid. The biggest part of the emission came from materials preparation accounting for more than 50% of the emissions. If NMC pouch cell is used, the total emission increases to almost 10 kg COe kg battery"" while materials manufacturing still contributes to more than 50% of the emission. During the end-of-life management phase, the refurbishing process adds little emission to the lifecycle emission. The recycling process, on the other hand, as suggested by Ciez and Whitacre emits a significant amount of GHG. As shown in the battery recycling emission plot a and c, the emission of the recycling process varies with the different recycling processes, different chemistry and different form factor. Thus, the net emission avoided compared to not recycling also varies with these factors. At a glance, as shown in the plot b and d, the direct recycling process is the most ideal process for recycling pouch cell batteries, while the hydrometallurgical process is most suitable for cylindrical type battery. However, with the error bars shown, the best approach cannot be picked with confidence. It is worth noting that for the lithium iron phosphates (LFP) chemistry, the net benefit is negative. Because LFP cells lacks cobalt and nickel which are expensive and energy intensive to produce, it is more energetically efficient to mine. In general, in addition to promoting the growth of a single sector, a more integrated effort should be in place to reduce the lifecycle emission of EV batteries. A finite total supply of rare earth material can apparently justify the need for recycling. But the environmental benefit of recycling needs closer scrutiny. Based on current recycling technology, the net benefit of recycling depends on the form factors, the chemistry and the recycling process chosen.
https://en.wikipedia.org/wiki?curid=15452708
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Mitochondrial replacement therapy (MRT), where the nuclear DNA is transferred to another healthy egg cell leaving the defective mitochondrial DNA behind, is an IVF treatment procedure. Using a similar pronuclear transfer technique, researchers at Newcastle University led by Douglass Turnbull successfully transplanted healthy DNA in human eggs from women with mitochondrial disease into the eggs of women donors who were unaffected. In such cases, ethical questions have been raised regarding biological motherhood, since the child receives genes and gene regulatory molecules from two different women. Using genetic engineering in attempts to produce babies free of mitochondrial disease is controversial in some circles and raises important ethical issues. A male baby was born in Mexico in 2016 from a mother with Leigh syndrome using MRT.
https://en.wikipedia.org/wiki?curid=160125
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He is frequently recognized within the field of economics (Who’s Who in Economics, Millennium Edition, and The Changing Face of Economics: Conversations with Cutting Edge Economists 2004) and the field of ecological economics (Kenneth E. Boulding Award, 2006) for both his critiques of and contributions to economics even while he has dedicated most of his time working across disciplinary ways of understanding. The American Association for the Advancement of Science elected Norgaard to the status of “Fellow” in 2007. His research emphasizes how the resolution of complex socio-environmental problems challenges modern beliefs about science and policy and explores development as a process of coevolution between social and environmental systems. His writing is informed through work on energy, environment, and development issues around the globe with different periods of his efforts emphasizing Alaska, Brazil, and California.
https://en.wikipedia.org/wiki?curid=41162191
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The matrices of the two firms also differ in terms of depth, the image inside the matrix, implementation, and size. For example, the American matrices are shallower by 0.025  mm (0.010   inch), and consequently the interior of American foundry moulds need to be higher to produce characters with a type height of 23.3  mm (0.918   inch). This was one of many measures taken by the two Monotype companies to divide the world market between themselves. For example, the Americans served the Americas and the Canadian markets. The British company, The Monotype Corporation Ltd. in Salfords, had many customers in India, Africa, and Asia. For these countries many non-Latin typefaces were created for printing in Hebrew, Javanese, Sanskrit, Sinhala, Thai, and other languages.
https://en.wikipedia.org/wiki?curid=52068806
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The differential dynamical mode described here, also called the small signal model, is the only intrinsic small signal model of the avalanche transistor. Stray elements due to the package enclosing the transistor are deliberately neglected, since their analysis would not add anything useful from the point of view of the working principles of the avalanche transistor. However, when realizing an electronic circuit, those parameters are of great importance. Particularly, stray inductances in series with collector and emitter leads have to be minimized to preserve the high speed performance of avalanche transistor circuits. Also, this equivalent circuit is useful when describing the behavior of the avalanche transistor near its turn on time, where collector currents and voltages are still near their quiescent values: in the real circuit it permits the calculation of time constants and therefore rise and fall times of the formula_34 waveform. However, since avalanche transistor switching circuits are intrinsically large signal circuits, the only way to predict with reasonable accuracy their real behaviour is to do numerical simulations. Again, the analysis closely follows that of William D. Roehr in .
https://en.wikipedia.org/wiki?curid=2773192
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The next part of this article deals with the basic theory of cold field electron emission from bulk metals. This is best treated in four main stages, involving theory associated with: (1) derivation of a formula for "escape probability", by considering electron tunneling through a rounded triangular barrier; (2) an integration over internal electron states to obtain the "total energy distribution"; (3) a second integration, to obtain the emission current density as a function of local barrier field and local work function; (4) conversion of this to a formula for current as a function of applied voltage. The modified equations needed for large-area emitters, and issues of experimental data analysis, are dealt with separately.
https://en.wikipedia.org/wiki?curid=293392
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In the presence of sufficiently strong and independent log-normal shadow fading (or shadowing) and a singular power-law attenuation function, it was observed by simulation for hexagonal networks and then later mathematically proved that for general stationary (including hexagonal) networks that quantities like the SINR and SIR of the typical user behave stochastically as though the underlying network were Poisson. In other words, given a path loss function, using a Poisson cellular network model with constant shadowing is equivalent (in terms of SIR, SINR, etc.) to assuming sufficiently large and independent fading or shadowing in the mathematical model with the base stations positioned according to either a deterministic or random configuration with a constant density.
https://en.wikipedia.org/wiki?curid=40521609
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Other fields of probability were developed and used to study stochastic processes, with one main approach being the theory of large deviations. The theory has many applications in statistical physics, among other fields, and has core ideas going back to at least the 1930s. Later in the 1960s and 1970s fundamental work was done by Alexander Wentzell in the Soviet Union and Monroe D. Donsker and Srinivasa Varadhan in the United States of America, which would later result in Varadhan winning the 2007 Abel Prize. In the 1990s and 2000s the theories of Schramm–Loewner evolution and rough paths were introduced and developed to study stochastic processes and other mathematical objects in probability theory, which respectively resulted in Fields Medals being awarded to Wendelin Werner in 2008 and to Martin Hairer in 2014.
https://en.wikipedia.org/wiki?curid=47895
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Cryopyrin-associated periodic syndrome (CAPS) is a group of rare, heterogeneous autoinflammatory disease characterized by interleukin 1β-mediated systemic inflammation and clinical symptoms involving skin, joints, central nervous system, and eyes. It encompasses a spectrum of three clinically overlapping autoinflammatory syndromes including familial cold autoinflammatory syndrome (FCAS, formerly termed familial cold-induced urticaria), the Muckle–Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disease (NOMID, also called chronic infantile neurologic cutaneous and articular syndrome or CINCA) that were originally thought to be distinct entities, but in fact share a single genetic mutation and pathogenic pathway, and keratoendotheliitis fugax hereditaria in which the autoinflammatory symptoms affect only the anterior segment of the eye.
https://en.wikipedia.org/wiki?curid=23099118
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According to a roadmap published by VESA in September 2016, a new version of DisplayPort was intended to be launched in "early 2017". It would have improved the link rate from 8.1 to 10.0Gbit/s, a 23% increase. This would have increased the total bandwidth from 32.4Gbit/s to 40.0Gbit/s. However, no new version was released in 2017, likely delayed to make further improvements after the HDMI Forum announced in January 2017 that their next standard (HDMI2.1) would offer up to 48Gbit/s of bandwidth. According to a press release on 3 January 2018, "VESA is also currently engaged with its members in the development of the next DisplayPort standard generation, with plans to increase the data rate enabled by DisplayPort by two-fold and beyond. VESA plans to publish this update within the next 18 months." At CES 2019, VESA announced that the new version would support 8K @ 60Hz without compression and was expected to be released in the first half of 2019.
https://en.wikipedia.org/wiki?curid=2515655
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Recently, many observations on mesoscale eddies in the ocean have been made using sea surface height data from altimeters. It has been shown that regions with the highest growth rate of baroclinic instabilities indeed match the regions which are rich in eddies. Furthermore, also the trajectories of both cyclonic and anticyclonic eddies can be studied. From this it follows that there are approximately the same number of cyclonic and anticyclonic eddies observed and therefore it is concluded that the generation of these two types is very similar. However, when considering longer lived eddies, they found that anticyclonic eddies clearly dominate. This implies that cyclonic eddies are less stable and therefore decay more rapidly. In addition, there are no eddies present above shallows in the ocean due to topographic steering as a result of the Taylor–Proudman theorem. Lastly, extremely long lived eddies with lifetimes over 1.5 to 2 years are only found in gyres, most likely because the background flow is small here.
https://en.wikipedia.org/wiki?curid=67686875
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After the cancellation of the A-12, the Navy elected to purchase the F/A-18E/F Super Hornet, which went on to replace the A-6 Intruder and the F-14 Tomcat. The Super Hornet uses the General Electric F414 turbofan engine, which is a modified variant of the upgraded F404 version developed for the A-12. The full-size A-12 mockup was revealed to the public at the Naval Air Station Joint Reserve Base Fort Worth in June 1996. The cancellation of the A-12 is seen as one of the major losses in the 1990s that weakened McDonnell Douglas and led to its merger with rival Boeing in 1997. After years of being in storage at the Lockheed Martin Aeronautics (formerly General Dynamics) facility in Fort Worth, Texas, the mockup was transported to Veterans Memorial Air Park adjacent to Meacham Airport in north Fort Worth in June 2013. (The park was later renamed Fort Worth Aviation Museum.)
https://en.wikipedia.org/wiki?curid=574228
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The University of Alaska Southeast's main campus is located in Juneau. The majority of the campus lies between Auke Bay and Auke Lake. The campus consists of classrooms, studios, teaching and research labs, the Anderson Science building (North Pacific Marine Lab), the William A. Egan Library, housing, the Student Recreation Center (Charles Gamble Jr.-Donald Sperl Joint Use Facility), and office and administrative spaces. UAS also has a Technical Education Center, located in downtown Juneau, which consists of technical, construction and mechanical labs, a mine simulator, and classroom and office space. The Juneau campus offers Occupational Endorsements, Certificates, Associate, Baccalaureate, and Graduate degrees.
https://en.wikipedia.org/wiki?curid=611159
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The main role of the Met Office is to produce forecast models by gathering information from weather satellites in space and observations on earth, then processing it with a variety of models, based on a software package known as the unified model. The principal weather products for UK customers are 36-hour forecasts from the operational 1.5 km resolution UKV model covering the UK and surroundings (replacing the 4 km model), 48-hour forecasts from the 12 km resolution NAE model covering Europe and the North Atlantic, and 144-hour forecasts from the 25 km resolution global model (replacing the 40 km global model). The Met Office's Global Model forecast has consistently been in the top 3 for global weather forecast performance (in the decades up to 2010) in independent verification to WMO standards. Products for other regions of the globe are sold to customers abroad, provided for MOD operations abroad or provided free to developing countries in Africa. If necessary, forecasters may make adjustments to the computer forecasts. Data is stored in the Met Office's own PP-format.
https://en.wikipedia.org/wiki?curid=319671
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Shennong has tested hundreds of herbs to find their medical value, and have written "The Divine Farmer's Herb-Root Classic". This book recorded the efficacy of 365 medicines derived from plants, animals, and minerals and gave rarity ratings and grade. Shennong's work led the way to Chinese medicine. In the Ming Dynasty, Li Shizhen wrote "Compendium of Materia Medica" which contained more than 1,800 kinds of drugs. It also described the nature, flavor, form, type and usage in disease cure of over 1000 herbs. The book is considered as the primary reference work for herbal preparation. These works were significant to the development of traditional Chinese medicine, and they laid the foundation for modern Chinese medical chemistry.
https://en.wikipedia.org/wiki?curid=60696089
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In addition to solving the problems of flicker, electronic ballasts also provide other advantages over magnetic ballasts. With a square wave voltage, the cathodes spend much more time emitting electrons and exciting the plasma, creating a gain of 5–10% in lumen output. The square-wave nature of the power flow allows lamp life to be extended by as much as 20%. Most modern ballasts are now also equipped with a dimmer, which uses pulse-width modulation to dim the lamp up to 50%, or as much as one stop of light. Unlike a tungsten-based light, which has a negative color temperature shift with a drop in power, the mercury emission spectra takes over with a drop in power (approximately 200 K bluer at 50% output).
https://en.wikipedia.org/wiki?curid=1723027
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Due to their delocalized electronic structure, 1,2-dithiolene complexes undergo reversible redox reaction. When oxidized, dithiolene complexes have greater 1,2-dithioketone character. In reduced complexes, the ligand assumes more ene-1,2-dithiolate character. These descriptions are evaluated by examination of differences in C-C and C-S bond distances. The true structure lies somewhere between these resonance structures. Reflecting the impossibility to provide an unequivocal description of the structure, McCleverty introduced the term 'dithiolene' to give a general name for the ligand that does not specify a particular oxidation state. This suggestion was generally accepted, and 'dithiolene' is now a universally accepted term. Only more recently the radical nature of monoanionic 1,2-dithiolene ligands has been pointed out. While few examples of authentic dithiolene radicals have been reported, diamagnetism in neutral bis(1,2-dithiolene) complexes of divalent transition metal ions should be considered as a consequence of a string antiferromagnetic coupling between the two radical ligands.
https://en.wikipedia.org/wiki?curid=3661080
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They also learned from those enemies. The operations of Scipio were an improvement on some of those who had previously faced Hannibal, showing a higher level of advance thinking, preparation and organization. (Compare with Sempronius at the Battle of the Trebia River for example). Scipio's contribution was in part to implement more flexible manoeuvre of tactical units, instead of the straight-ahead, three-line grind favoured by some contemporaries. He also made better use of cavalry, traditionally an arm in which the Romans were lacking. His operations also included pincer movements, a consolidated battle line, and "reverse Cannae" formations and cavalry movements. His victories in Spain and the African campaign demonstrated a new sophistication in Roman warfare and reaffirmed the Roman capacity to adapt, persist and overcome. See detailed battles:
https://en.wikipedia.org/wiki?curid=30855309
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Down syndrome by itself (i.e. in the absence of "GATA1" gene mutations) is a cause for numerous hematological abnormalities which are similar to those seen in TMD. These Down syndrome-related abnormalities include increased numbers of stem cell precursors to platelets and red blood cells, impaired maturation of these precursors to platelets and red blood cells, thrombocytopenia, abnormal bleeding, anemia, leukocytosis, and serious liver damage. Since TMD is restricted to individuals with Down syndrome or otherwise have an excess of key chromosome 21 genes, it is suggested that certain chromosome 21 genes that are in triplicate and cause these hematological disorders in Down syndrome are essential for the development of "GATA1" inactivating mutations and thereby TMD. These genes include "ERG", a potentially cancer-causing oncogene that codes for a transcription factor; "DYRK1A", which codes for a protein kinase type of enzyme involved in promoting cellular proliferation; and "RUNX1", which codes for a transcription factor that regulates the maturation of hematological stem cells and, when mutated, is involved in the development of various myeloid neoplasms.
https://en.wikipedia.org/wiki?curid=68511227
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The Manchester Baby of 1948 along with the Manchester Mark 1 and EDSAC both of 1949 were the world's earliest working computers that stored program instructions and data in the same space. In this they implemented the stored-program concept which is frequently (but erroneously) attributed to a 1945 paper by John von Neumann and colleagues. Von Neumann is said to have given due credit to Alan Turing, and the concept had actually been mentioned earlier by Konrad Zuse himself, in a 1936 patent application (that was rejected). Konrad Zuse himself remembered in his memoirs: "During the war it would have barely been possible to build efficient stored program devices anyway." and Friedrich L. Bauer wrote: "His visionary ideas (live programs) which were only to be published years afterwards aimed at the right practical direction but were never implemented by him."
https://en.wikipedia.org/wiki?curid=152671
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He later looked at the role of nitric oxide and angiotensin converting enzyme in controlling blood vessel tone. In 1987, he set out with Patrick Vallance to investigate whether human blood vessels demonstrated endothelium-dependent relaxation, a term coined in 1980 by Robert F. Furchgott and John V. Zawadzki after discovering that a large blood vessel would not relax when its single-layered inner most lining was removed. They subsequently showed that the occurrence was mediated by what they called endothelium-derived relaxing factor, later found to be nitric oxide, and it was subsequently shown to occur in a variety of animals. Using veins from the back of a human hand, Collier and his team reproduced Furchgott and Zawadzki's findings. They then demonstrated that the human arterial vasculature is actively dilated by a continuous release of nitric oxide. In 1996, Vallance presented his and Collier's findings at the Goulstonian Lecture of the Royal College of Physicians, where he gave details of the connection between nitric oxide and blood pressure.
https://en.wikipedia.org/wiki?curid=54423925
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Crystal methamphetamine (most commonly, colloquially known as "crystal meth" or "ice") and free base forms of amphetamine are sufficiently volatile substances and this allows them to be vaporized by high heat (i.e. using a lighter) and the fumes are inhaled (or "smoked") from glass paraphernalia known as base pipes (most commonly, colloquially referred to as "bowl", "globe" or simply "pipe"). The National Drug Strategy Household Survey 2016 by the Australian Institute of Health and Welfare revealed that smoking is an increasingly favored route of administration among methamphetamine users in Australia. The National Drug Strategy Household Survey 2019 suggests overall rates of methamphetamine use have declined over recent years, but among those who do use methamphetamine, 'ice' is the more popular form of the drug, and those who use 'ice' (as opposed to other forms of methamphetamine) are more likely to use it more regularly.
https://en.wikipedia.org/wiki?curid=40542151
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One of the primary ways niche-sharing species can coexist is the competition-colonization trade-off. In other words, species that are better competitors will be specialists, whereas species that are better colonizers are more likely to be generalists. Host-parasite models are effective ways of examining this relationship, using host transfer events. There seem to be two places where the ability to colonize differs in ecologically closely related species. In feather lice, Bush and Clayton provided some verification of this by showing two closely related genera of lice are nearly equal in their ability to colonize new host pigeons once transferred. Harbison continued this line of thought by investigating whether the two genera differed in their ability to transfer. This research focused primarily on determining how colonization occurs and why wing lice are better colonizers than body lice. Vertical transfer is the most common occurrence, between parent and offspring, and is much-studied and well understood. Horizontal transfer is difficult to measure, but in lice seems to occur via phoresis or the "hitchhiking" of one species on another. Harbison found that body lice are less adept at phoresis and excel competitively, whereas wing lice excel in colonization.
https://en.wikipedia.org/wiki?curid=451120
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For a domain obtained by excising formula_3 ∪ {∞} from finitely many disjoint closed disks, the conformal mapping onto a slit horizontal or vertical domains can be made explicit and presented in closed form. Thus the Poisson kernel on any of the disks can be used to solve the Dirichlet problem on the boundary of the disk as described in . Elementary properties such as the maximum principle and the Schwarz reflection principle apply as described in . For a specific disk, the group of Möbius transformations stabilizing the boundary, a copy of , acts equivariantly on the corresponding Poisson kernel. For a fixed in , the Dirichlet problem with boundary value || can be solved using the Poisson kernels. It yields a harmonic function on . The difference = || is called the Green's function with pole at . It has the important symmetry property that = , so it is harmonic in both variables when it makes sense.
https://en.wikipedia.org/wiki?curid=50964981
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In 2007, Smith was said to admit uncertainty regarding her Cherokee descent to scholar Patti Jo King and Richard Allen at a conference, apologizing and agreeing to set the record straight. Native lawyer Steve Russell (Cherokee Nation) publicly accused Smith of ethnic fraud in a 2008 editorial published by "Indian Country Today," but it was not widely read. Smith failed to set the record straight, and her lack of documented Cherokee descent became "something of an open secret" until 2015. She continued to be identified at professional events as Cherokee or Native American, and claimed it was part of the reason for her denial of tenure at the University of Michigan (see above). Following the media attention surrounding activist Rachel Dolezal in 2015, who falsely claimed African-American identity, an anonymous Tumblr blog entitled "Andrea Smith is not Cherokee", was published, listing a chronology of book and conference biographies of Smith that refer to her purported Cherokee ancestry.
https://en.wikipedia.org/wiki?curid=13273404
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Reed President Richard Scholz in 1922 called the educational program as a whole "an honest effort to disregard old historic rivalries and hostilities between the sciences and the arts, between professional and cultural subjects, and, ... the formal chronological cleavage between the graduate and the undergraduate attitude of mind". The Humanities program, which came into being in 1943 (as the union of two year-long courses, one in "world" literature, the other in "world" history) is one manifestation of this effort. One change to the program was the addition of a course in Chinese Civilization in 1995. The faculty has also recently approved several significant changes to the introductory syllabus. These changes include expanding the parameters of the course to include more material regarding urban and cultural environments.
https://en.wikipedia.org/wiki?curid=25417
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The most common approach to measuring the Dunning–Kruger effect is to compare self-assessment with objective performance. The self-assessment is sometimes called "subjective ability" in contrast to the "objective ability" corresponding to the actual performance. The self-assessment may be done before or after the performance. If done afterward, it is important that the participants receive no independent clues during the performance as to how well they did. So, if the activity involves answering quiz questions, no feedback is given as to whether a given answer was correct. The measurement of the subjective and the objective abilities can be in absolute or relative terms. When done in absolute terms, self-assessment and performance are measured according to absolute standards, e.g. concerning how many quiz questions were answered correctly. When done in relative terms, the results are compared with a peer group. In this case, participants are asked to assess their performances in relation to the other participants, for example in the form of estimating the percentage of peers they outperformed. The Dunning–Kruger effect is present in both cases, but tends to be significantly more pronounced when done in relative terms. So people are usually more accurate when predicting their raw score than when assessing how well they did relative to their peer group.
https://en.wikipedia.org/wiki?curid=2288777
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In a later series of papers, Russell developed aspects of this mode further. Employing an adult Australian sample, she tested the association between brow ridge formation and anterior dental loading, via the craniofacial angle (prosthion-nasion-metopion), maxilla breadth, and discontinuities in food preparation such as those observed between different age groups. Finding strong support for the first two criteria, she concluded that the supraorbital complex is formed as a result of increased tension due to the widening of the maxilla, thought to be positively correlated with the size of the masseter muscle, as well as with the improper orientation of bone in the superior orbital region.
https://en.wikipedia.org/wiki?curid=2835531
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During 2011–2014, SpaceX considered as many as seven potential locations around the country for a new private launch facility for orbital flights, including Alaska, California, Florida, Texas, Virginia, Georgia, and Puerto Rico. One of the proposed locations for the new commercial-mission-only spaceport was south Texas, which was revealed in April 2012, via preliminary regulatory documentation. The FAA's Office of Commercial Space Transportation began a multi-year process to conduct an Environmental Impact Statement and public hearings on the new launch site, which would be located in Cameron County, Texas. The site was to initially support up to 12 commercial launches per year, including two Falcon Heavy launches.
https://en.wikipedia.org/wiki?curid=40305820
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"Philae" mission was to land successfully on the surface of a comet, attach itself, and transmit data about the comet's composition. The "Rosetta" spacecraft and "Philae" lander were launched on an Ariane 5G+ rocket from French Guiana on 2 March 2004, 07:17 UTC, and travelled for 3,907 days (10.7 years) to Churyumov–Gerasimenko. Unlike the "Deep Impact" probe, which by design struck comet Tempel 1's nucleus on 4 July 2005, "Philae" is not an impactor. Some of the instruments on the lander were used for the first time as autonomous systems during the Mars flyby on 25 February 2007. CIVA, one of the camera systems, returned some images while the "Rosetta" instruments were powered down, while ROMAP took measurements of the Martian magnetosphere. Most of the other instruments needed contact with the surface for analysis and stayed offline during the flyby. An optimistic estimate of mission length following touchdown was "four to five months".
https://en.wikipedia.org/wiki?curid=524434
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Snow falls intermittently and mainly affects northern and eastern areas, high ground in Wales and especially the mountains of Scotland, where there is often enough snow lying to permit skiing at some of the five Scottish ski resorts. These resorts usually operate between December and April, depending on the snowfall. Frequently in the mountains potent depressions may move in from the north in the form of "polar lows", introducing heavy snow and often blizzard-like conditions to parts of the United Kingdom, particularly Scotland. Blizzards have become rarer in the 21st century, although much of England was affected by one on 30 January 2003. During periods of light winds and high pressure, frost and fog can become a problem and can pose a major hazard to drivers.
https://en.wikipedia.org/wiki?curid=84358
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In addition to about one-order-of-magnitude improvement in the bulk sensitivity, the advance in the momentum resolution is also very significant: the photoelectrons will be more broadly dispersed in emission angle when the energy of incident photon decreases. In other words, for a given angular resolution of the electron spectrometer, the lower photon energy leads to higher momentum resolution. The typical momentum resolution of a 6 eV laser-based ARPES is approximately 8 times better than that of a 50 eV synchrotron radiation ARPES. Besides, the better momentum resolution due to low photon energy also results in less k-space accessible to ARPES which is helpful to the more precise spectrum analysis. For instance, in the 50 eV synchrotron ARPES, electrons from the first 4 Brillouin zones will be excited and scattered to contribute to the background of photoelectron analysis. However, the small momentum of 6 eV ARPES will only access some part of the first Brillouin zone and therefore only those electrons from small region of k-space can be ejected and detected as the background. The reduced inelastic scattering background is desirable while doing the measurement of weak physical quantities, in particular the high-Tc superconductors.
https://en.wikipedia.org/wiki?curid=19870711
2,148,909
1,843,067
U-PARC is home to academic programs and to more than 100 companies from all over the world, including several Fortune 500 companies. U-PARC's pilot plant services range from petroleum, petrochemical, and chemical-based technologies to environmental, synthetic fuels, biotechnology, and other emerging technologies. Buildings are connected indoors throughout the campus via tunnels. On-site amenities include 24-hour monitored access points, free parking, catering service, meeting/conference space, a U.S. Postal Service sub-station, a credit union, ATMs, picnic areas, outdoor dining, volleyball courts, locker rooms, and shower facilities.
https://en.wikipedia.org/wiki?curid=22828647
1,842,014
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Some video games have used gestures. For example, in the "" real-time tactics series, originally created by Bungie, players use them to order battlefield units to face in a desired direction. Another game using gestures is Lionhead's "Black & White". The game "Arx Fatalis" uses mouse gestures for drawing runes in the air to cast spells. Several Nintendo Wii games take advantage of such a system. "Ōkami" uses a system similar to mouse gestures; the player can enter a drawing mode in which the shape they create (circle, lightning bolt, line, etc.) performs a function in the game such as creating a bomb or changing the time from night to day. Other examples of computer games that use mouse gestures are "Die by the Sword" and "Silver" where basic mouse gestures actually map attack moves and such in real-time combat, along with "", which has a control scheme that implements its titular rider "reflex" system with mouse gestures.
https://en.wikipedia.org/wiki?curid=20736
1,431,636
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There are many types of chassis dynamometer according to the target application - for example, emissions measurement, miles accumulation chassis dynamometer (MACD), Noise-Vibration-Harshness (NVH or "Acoustic") Application, Electromagnetic Compatibility (EMC) testing, end of line (EOL) tests, performance measurement and tuning. Another basic division is by type of vehicle - motorcycles, cars, trucks, tractors or the size of the roller - mostly 25", 48", 72", but also any other. Modern dynamometers used for development are mostly one roller to the wheel construction and the vehicle wheel is placed the top of the roller. Older constructional solutions are two roller per wheel and vehicle is place between these rollers - this design solution is cheaper and simpler, however, due to the requirements for accuracy and strict limits is no longer used for the development of new vehicles, but only as a test dynamometer at the end of the line or to measure the performance of the engine without dismantling, or performance tuning in "garage" companies.
https://en.wikipedia.org/wiki?curid=53306867
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The process of domestication, by which only a choice few wild individuals are cultivated and selected against, often results in very strong selective pressures. This is evident in the genomes of these individuals as a lack of genetic diversity. In some cases this lack of diversity is seen as a selective sweep, whereby the variation at a particular locus of the genome is highly reduced while variation outside of this area is maintained or only partially reduced. In other cases, such as the coconut, genomic studies have revealed occurrences of a founder event, whereby the genetic diversity of an entire population is reduced due to a small number of individuals with low diversity being the isolated ancestors of a larger modern population. Bottlenecks, where variation is reduced throughout the entire genome, are also evident in crop species such as pearl millet, cotton, common bean and lima bean. With the identification of bottlenecks in these species, researchers are able to study the effects on an organisms' ability to evolve past a bottleneck, and what effects this may have on the genomes of both individuals and populations as well as their fitness.
https://en.wikipedia.org/wiki?curid=33890453
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Because the economics of climate change mitigation depend greatly on how quickly carbon neutrality needs to be achieved, climate sensitivity estimates can have important economic and policy-making implications. One study suggests that halving the uncertainty of the value for transient climate response (TCR) could save trillions of dollars. Scientists are uncertain about the precision of estimates of greenhouse gas increases on future temperature since a higher climate sensitivity would mean more dramatic increases in temperature, which makes it more prudent to take significant climate action. If climate sensitivity turns out to be on the high end of what scientists estimate, the Paris Agreement goal of limiting global warming to well below 2 °C cannot be achieved, and temperature increases will exceed that limit, at least temporarily. One study estimated that emissions cannot be reduced fast enough to meet the 2 °C goal if equilibrium climate sensitivity (the long-term measure) is higher than . The more sensitive the climate system is to changes in greenhouse gas concentrations, the more likely it is to have decades when temperatures are much higher or much lower than the longer-term average.
https://en.wikipedia.org/wiki?curid=1765281
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Unlike most animals, plants grow new organs after embryogenesis, including new roots, leaves, and flowers. In the flowering plants, the gynoecium develops in the central region of the flower as a carpel or in groups of fused carpels. After fertilization, the gynoecium develops into a fruit that provides protection and nutrition for the developing seeds, and often aids in their dispersal. The gynoecium has several specialized tissues. The tissues of the gynoecium develop from genetic and hormonal interactions along three-major axes. These tissue arise from meristems that produce cells that differentiation into the different tissues that produce the parts of the gynoecium including the pistil, carpels, ovary, and ovals; the carpel margin meristem (arising from the carpel primordium) produces the ovules, ovary septum, and the transmitting track, and plays a role in fusing the apical margins of carpels.
https://en.wikipedia.org/wiki?curid=2394288
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In January 2012, the Zen program won 3:1 in a Go match on a 19×19 board with an amateur 2 dan player. Google Deepmind developed the program AlphaGo, which in October 2015 became the first Computer Go program to beat a professional human Go player without handicaps on a full-sized 19x19 board. In March 2016, AlphaGo was awarded an honorary 9-dan (master) level in 19×19 Go for defeating Lee Sedol in a five-game match with a final score of four games to one. AlphaGo represents a significant improvement over previous Go programs as well as a milestone in machine learning as it uses Monte Carlo tree search with artificial neural networks (a deep learning method) for policy (move selection) and value, giving it efficiency far surpassing previous programs.
https://en.wikipedia.org/wiki?curid=40528449
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In his writings Professor Sharma has focused on early Indian social structure, material and economic life, state formation and political ideas and the social context of religious ideologies and has sought to underline the historical processes which shaped Indian culture and civilisation. In his study of each of these aspects of Ancient Indian History he has laid stress on the elements of change and continuity. This has significantly conditioned his methodology which basically rests on a critical evaluation of sources and a correlation between literary texts with archaeology and ethnography. His methodology is being increasingly extended to the study of various aspects of Indian history just as the problems studied by him and the questions raised by him have generated a bulk of historical literature in recent years.
https://en.wikipedia.org/wiki?curid=6989422
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In "Fundamental limitations on plasma fusion systems not in thermodynamic equilibrium", Todd Rider argues that a quasineutral isotropic plasma will lose energy due to Bremsstrahlung at a rate prohibitive for any fuel other than D-T (or possibly D-D or D-He3). This paper is not applicable to IEC fusion, as a quasineutral plasma cannot be contained by an electric field, which is a fundamental part of IEC fusion. However, in an earlier paper, "A general critique of inertial-electrostatic confinement fusion systems", Rider addresses the common IEC devices directly, including the fusor. In the case of the fusor the electrons are generally separated from the mass of the fuel isolated near the electrodes, which limits the loss rate. However, Rider demonstrates that practical fusors operate in a range of modes that either lead to significant electron mixing and losses, or alternately lower power densities. This appears to be a sort of catch-22 that limits the output of any fusor-like system.
https://en.wikipedia.org/wiki?curid=42889
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FMD occurs throughout much of the world, and while some countries have been free of FMD for some time, its wide host range and rapid spread represent cause for international concern. After World War II, the disease was widely distributed throughout the world. In 1996, endemic areas included Asia, Africa, and parts of South America; as of August 2007, Chile is disease-free, and Uruguay and Argentina have not had an outbreak since 2001. In May 2014, the FAO informed that Bolivia, Colombia, Ecuador and Peru were "just one step away" from eradication; North America and Australia have been free of FMD for many years. New Zealand has never had a case of foot-and-mouth disease. Most European countries have been recognized as disease-free, and countries belonging to the European Union have stopped FMD vaccination.
https://en.wikipedia.org/wiki?curid=21438755
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Like all species of "Russula", "R. emetica" is mycorrhizal, and forms mutually beneficial partnerships with roots of trees and certain herbaceous plants. Preferred host plants are conifers, especially pines. Fruit bodies grow singly, scattered, or in groups in sphagnum moss near bogs, and in coniferous and mixed forests. The fungus occasionally fruits on humus or on very rotten wood. The mushroom is known from North Africa, Asia and Europe and can be locally very common. There is some doubt over the extent of its range in North America, as some sightings refer to the related "R. silvicola"; initially the name "Russula emetica" was often applied to any red-capped white "Russula". Sightings in Australia are now referred to the similarly coloured "R. persanguinea".
https://en.wikipedia.org/wiki?curid=4243203
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Because of this codification approach, a single named statute (like the Taft–Hartley Act or the Embargo Act) may or may not appear in a single place in the Code. Often, complex legislation bundles a series of provisions together as a means of addressing a social or governmental problem; those provisions often fall in different logical areas of the Code. For example, an Act providing relief for family farms might affect items in Title 7 (Agriculture), Title 26 (Tax), and Title 43 (Public Lands). When the Act is codified, its various provisions might well be placed in different parts of those various Titles. Traces of this process are generally found in the Notes accompanying the "lead section" associated with the popular name, and in cross-reference tables that identify Code sections corresponding to particular Acts of Congress.
https://en.wikipedia.org/wiki?curid=32211
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Congress supported NERVA again in 1972. A bipartisan coalition headed by Smith and Cannon appropriated $100 million for the small NERVA engine that would fit inside the shuttle's cargo bay that was estimated to cost about $250 million over a decade. They added a stipulation that there would be no more reprogramming NERVA funds to pay for other NASA activities. The Nixon administration decided to cancel NERVA anyway. On 5 January 1973, NASA announced that NERVA was terminated. Staff at LASL and SNPO were stunned; the project to build a small NERVA had been proceeding well. Layoffs began immediately, and the SNPO was abolished in June. After 17 years of research and development, Projects Nova and NERVA had spent about $1.4 billion, but NERVA had never flown.
https://en.wikipedia.org/wiki?curid=712716
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In Taiwan, a 2010 study observed flower urchins spawning in May on the years 2007 and 2009. They occurred on highly similar conditions: in the afternoon low tide of the spring tide immediately after a new moon. During the event, spawning individuals discard the debris that usually cover their bodies before releasing their gametes into the water. Another study published in 2013 did not find any obvious correlation between lunar and tidal cycles to the mass spawning behavior of the flower urchin populations in southern Taiwan. It did note that the spawning patterns appeared to be non-random, with higher spawning rates on daytime on certain dates. However, the study was conducted within a span of only five months (from April to August 2010).
https://en.wikipedia.org/wiki?curid=29096764
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He made his debut for Consejo Mundial de Lucha Libre in the summer of 2008 under the ring name "Niño de Acero", Spanish for "Boy of Steel", the nickname of the Comic book hero Superboy. In September 2008 CMLL decided to add another championship to their Mini-Estrellas division when they made the Mexican National Lightweight Championship Mini-Estrellas exclusive. Niño de Acero was placed in the first group of wrestlers hoping to qualify for the tournament final, but was eliminated in the "Torneo cibernetico" elimination match that took place on September 9, 2009. He competed in the 2009 "Pequeños Reyes del Aire" ("Little Kings of the Air") tournament, where he was the third man eliminated out of nine competitors in total. The Mini-Estrella division was featured in its first ever pay-per-view main event at CMLL's "La Hora Cero" ("Zero Hour") as 14 Mini-Estrellas all put their masks on the line in a Steel cage match where the last two people in the ring would have to wrestle under "Lucha de Apuesta" (bet match) rules inside the steel cage. Whoever lost the match would be forced to unmask per Lucha Libre traditions. Niño de Acero managed to climb out of the cage as the fifth overall escapee, ensuring that he did not have to risk his mask at the end of the match.
https://en.wikipedia.org/wiki?curid=37481555
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He entered the English East India Company at the age of fifteen and eventually became Clive's private secretary. During the 1757 Plassey campaign against the Nawab of Bengal, Siraj Ud Daulah, John Walsh was awarded £56,000 in prize money. Upon his return to England in 1759, his fortune was estimated at £147,000, and he quickly sought to purchase the necessary trappings of aristocratic power in eighteenth century Britain: land and political influence. In late 1764, Walsh purchased the large estate of Warfield Park, near Bracknell in Berkshire and spent the next two years doing it up. He was MP for Worcester from 1761 to 1780. He continued to serve Robert Clive, or 'Clive of India' as he became known, and attempted to form a parliamentary interest in his favour.
https://en.wikipedia.org/wiki?curid=2896955
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Medical treatment with anti-vertigo medications may be considered in acute, severe exacerbation of BPPV, but in most cases are not indicated. These primarily include drugs of the antihistamine and anticholinergic class, such as meclizine and hyoscine butylbromide (scopolamine), respectively. The medical management of vestibular syndromes has become increasingly popular over the last decade, and numerous novel drug therapies (including existing drugs with new indications) have emerged for the treatment of vertigo/dizziness syndromes. These drugs vary considerably in their mechanisms of action, with many of them being receptor- or ion channel-specific. Among them are betahistine or dexamethasone/gentamicin for the treatment of Ménière's disease, carbamazepine/oxcarbazepine for the treatment of paroxysmal dysarthria and ataxia in multiple sclerosis, metoprolol/topiramate or valproic acid/tricyclic antidepressant for the treatment of vestibular migraine, and 4-aminopyridine for the treatment of episodic ataxia type 2 and both downbeat and upbeat nystagmus. These drug therapies offer symptomatic treatment, and do not affect the disease process or resolution rate. Medications may be used to suppress symptoms during the positioning maneuvers if the person's symptoms are severe and intolerable. More dose-specific studies are required, however, in order to determine the most effective drug(s) for both acute symptom relief and long-term remission of the condition.
https://en.wikipedia.org/wiki?curid=1028498
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Since 1975, the art proper to postmodernism or postmodern art developed as opposed to the so-called modern art. These artists assumed the failure of the avant-garde movements as the failure of the modern project: the avant-garde intended to eliminate the distance between art and life, to universalize art; the postmodern artist, on the other hand, is self-referential, art talks about art, they do not intend to do social work. One of its exponents with achievements in graphic art is Eric Fischl, an American artist of realist style with a strong expressive character, influenced by Max Beckmann, Lucian Freud or Edward Hopper. His subject matter focused mainly on sexuality, with abundant representations of naked bodies, in erotic attitudes, but with a certain enigmatic, anguished, oppressive air, which is emphasized by his muted, grayish chromatic range, with a lighting of strange intensity that accentuates the expressive style of his works. The Spaniard Miquel Barceló has developed a versatile oeuvre in which multiple influences can be perceived -among which African art stands out-, with the use of diverse artistic techniques and procedures, from painting, sculpture and prints to ceramics and casting. He has worked with etching, aquatint, drypoint, lithography and serigraphy, in individual works ("Suite Tres Caprichos", 1988) or in book illustrations, such as "Divine Comedy" by Dante or "La música callada del toreo" by José Bergamín (2015).
https://en.wikipedia.org/wiki?curid=72166508
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The Fujita scale, introduced in 1971 as a means to differentiate tornado intensity and path area, assigned wind speeds to damage that were, at best, educated guesses. Fujita and others recognized this immediately and intensive engineering analysis was conducted through the rest of the 1970s. This research, as well as subsequent research, showed that tornado wind speeds required to inflict the described damage were actually much lower than the F-scale indicated, particularly for the upper categories. Also, although the scale gave general descriptions of damage a tornado could cause, it gave little leeway for strength of construction and other factors that might cause a building to sustain more damage at lower wind speeds. Fujita tried to address these problems somewhat in 1992 with the Modified Fujita Scale, but by then he was semi-retired and the National Weather Service was not in a position to update to an entirely new scale, so it went largely unenacted.
https://en.wikipedia.org/wiki?curid=165206
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The earliest applications of process control were mechanisms that adjusted the gap between mill stones for grinding grain and for keeping windmills facing into the wind. The centrifugal governor used for adjusting the mill stones was copied by James Watt for controlling speed of steam engines in response to changes in heat load to the boiler; however, if the load on the engine changed the governor only held the speed steady at the new rate. It took much development work to achieve the degree of steadiness necessary to operate textile machinery. A mathematical analysis of control theory was first developed by James Clerk Maxwell. Control theory was developed to its "classical" form by the 1950s. See: Control theory#History
https://en.wikipedia.org/wiki?curid=29432015
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Beyond biome "price tags," these environmental valuations can explore quite complex policy questions. For example, the Copenhagen Consensus think tank calculated that stemming the loss of coral reefs by 50 percent by 2030 would return more than $24 for every dollar spent. The Consensus' founder, Bjorn Lomborg, explains that ""coral reefs, which both act as fishery hatcheries and fishing resources while storing abundant numbers of species. At the same time, coral reefs possess an amazing beauty, which both shows up in large tourism revenues but also in most individuals saying they are willing to pay a certain amount to make sure they continue to exist for our grand children. … [Programs to preserve 50% more coral reef by 2030] cost about $3 billion per year but the total benefits likely run to at least $72, or about $24 dollars back for every dollar invested.""
https://en.wikipedia.org/wiki?curid=1300903
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Research published in 2012 found that the digital divide, as defined by access to information technology, does not exist amongst youth in the United States. Young people report being connected to the internet at rates of 94-98%. There remains, however, a civic opportunity gap, where youth from poorer families and those attending lower socioeconomic status schools are less likely to have opportunities to apply their digital literacy. The digital divide is also defined as emphasizing the distinction between the “haves” and “have-nots,” and presented all data separately for rural, urban, and central-city categories. Also, existing research on the digital divide reveals the existence of personal categorical inequalities between young and old people. An additional interpretation identified the gap between technology accessed by youth outside and inside the classroom.
https://en.wikipedia.org/wiki?curid=5169750
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A related and even rarer disorder named Maffucci syndrome is a very similar condition that is characterized by the presence of multiple enchondromas with hemangiomas and occasionally lymphangiomas usually near the hands and feet but not limited to the skull, ribs, and spinal bones. This disorder is also sporadic and nonhereditary and usually detected during childhood despite being a congenital condition. Maffucci syndrome has also similarly been linked to IDH1 and IDH2 mutations specifically the IDH1 R132C hotspot mutation. This hotspot mutation is presumed to be responsible for the spindle cell hemangiomas and enchondromas in cases of Maffucci syndrome. Sanger sequencing analysis concluded that exon 4 is the primary location of mutations in IDH1 and IDH2 genes are specifically responsible for hemangiomas. Maffucci syndrome carries a significantly higher risk of malignant transformations like chondrosarcomas but also much more aggressive tumors such as acute lymphocytic leukemia and gastrointestinal and ovarian malignancies.
https://en.wikipedia.org/wiki?curid=6898610
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Mosley started the Matlab Family Planning - Health Services Project by Cholera Research Laboratory in the late 1970s that involved household distribution of all available contraceptive methods in rural Bangladesh. With Mukhlisur Rahman, he preceded this Project with a study of the rapid decline in use of contraceptives in an earlier pill and condom distribution program, documenting the relevant factors amenable to program modification. The fact that this was method-oriented strategy instead of a client-oriented strategy was identified as the major factor leading to decline of contraceptive use. To counter this, Mosley, with Shushum Bhatia introduced various program modifications including offering the full range of contraceptive methods delivered by young village women who themselves were contraceptive users. This work was extended by others leading to the operational strategy for the Bangladesh national family planning program beginning in the 1980s.
https://en.wikipedia.org/wiki?curid=66001033
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Domestic applicants who have a disadvantaged financial background, are from rural or isolated areas, are from underrepresented schools, experienced difficult circumstances, have a disability or medical condition, are from a non-English speaking background, identify as an Indigenous Australian, or are applying through a non-school leaver entry pathway may be eligible for the Access Melbourne program. The program offered guaranteed entry in 2023 for students with ATARs of: Agriculture 72, Arts 88, Biomedicine 95, Commerce 93, Design 88, and Science 88. Minimum International Baccalaureate Diploma scores for undergraduate guaranteed entry in 2019 were: Agriculture 25, Arts 31, Biomedicine 38, Commerce 36, design 31, Science 31, Oral Health 31 (indicative only), Fine arts and Music were not applicable.
https://en.wikipedia.org/wiki?curid=363594
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Optically, the HST is a Cassegrain reflector of Ritchey–Chrétien design, as are most large professional telescopes. This design, with two hyperbolic mirrors, is known for good imaging performance over a wide field of view, with the disadvantage that the mirrors have shapes that are hard to fabricate and test. The mirror and optical systems of the telescope determine the final performance, and they were designed to exacting specifications. Optical telescopes typically have mirrors polished to an accuracy of about a tenth of the wavelength of visible light, but the Space Telescope was to be used for observations from the visible through the ultraviolet (shorter wavelengths) and was specified to be diffraction limited to take full advantage of the space environment. Therefore, its mirror needed to be polished to an accuracy of 10 nanometers, or about 1/65 of the wavelength of red light. On the long wavelength end, the OTA was not designed with optimum IR performance in mind—for example, the mirrors are kept at stable (and warm, about 15 °C) temperatures by heaters. This limits Hubble's performance as an infrared telescope.
https://en.wikipedia.org/wiki?curid=40203
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When Hamilton started using the term "software engineering" during the early Apollo missions, software development was not taken seriously compared to other engineering, nor was it regarded as a science. Hamilton was concerned with legitimizing software development as an engineering discipline. Over time the term "software engineering" gained the same respect as any other technical discipline. The IEEE Software September/October 2018 issue celebrates the 50th anniversary of software engineering. Hamilton talks about "Errors" and how they influenced her work related to software engineering and how her language, USL, could be used to prevent the majority of "Errors" in a system. Writing in "Wired", Robert McMillan noted: "At MIT she assisted in the creation of the core principles in computer programming as she worked with her colleagues in writing code for the world's first portable computer". Hamilton's innovations go beyond the feats of playing an important role in getting humans to the Moon. According to "Wired"s Karen Tegan Padir: "She, along with that other early programming pioneer, COBOL inventor Grace Hopper, also deserve tremendous credit for helping to open the door for more women to enter and succeed in STEM fields like software."
https://en.wikipedia.org/wiki?curid=28196618
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The equivalence of power laws with a particular scaling exponent can have a deeper origin in the dynamical processes that generate the power-law relation. In physics, for example, phase transitions in thermodynamic systems are associated with the emergence of power-law distributions of certain quantities, whose exponents are referred to as the critical exponents of the system. Diverse systems with the same critical exponents—that is, which display identical scaling behaviour as they approach criticality—can be shown, via renormalization group theory, to share the same fundamental dynamics. For instance, the behavior of water and CO at their boiling points fall in the same universality class because they have identical critical exponents. In fact, almost all material phase transitions are described by a small set of universality classes. Similar observations have been made, though not as comprehensively, for various self-organized critical systems, where the critical point of the system is an attractor. Formally, this sharing of dynamics is referred to as universality, and systems with precisely the same critical exponents are said to belong to the same universality class.
https://en.wikipedia.org/wiki?curid=24522
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GEKKO works on all platforms and with Python 2.7 and 3+. By default, the problem is sent to a public server where the solution is computed and returned to Python. There are Windows, MacOS, Linux, and ARM (Raspberry Pi) processor options to solve without an Internet connection. GEKKO is an extension of the APMonitor Optimization Suite but has integrated the modeling and solution visualization directly within Python. A mathematical model is expressed in terms of variables and equations such as the Hock & Schittkowski Benchmark Problem #71 used to test the performance of nonlinear programming solvers. This particular optimization problem has an objective function formula_1 and subject to the inequality constraint formula_2 and equality constraint formula_3. The four variables must be between a lower bound of 1 and an upper bound of 5. The initial guess values are formula_4. This optimization problem is solved with GEKKO as shown below.
https://en.wikipedia.org/wiki?curid=57256998
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The evolution of the tetrapods' internal nares was hotly debated in the 20th century. The internal nares could be one set of the external ones (usually presumed to be the posterior pair) that have migrated into the mouth, or the internal pair could be a newly evolved structure. To make way for a migration, however, the two tooth-bearing bones of the upper jaw, the maxilla and the premaxilla, would have to separate to let the nostril through and then rejoin; until recently, there was no evidence for a transitional stage, with the two bones disconnected. Such evidence is now available: a small lobe-finned fish called "Kenichthys", found in China and dated at around 395 million years old, represents evolution "caught in mid-act", with the maxilla and premaxilla separated and an aperture—the incipient choana—on the lip in between the two bones. "Kenichthys" is more closely related to tetrapods than is the coelacanth, which has only external nares; it thus represents an intermediate stage in the evolution of the tetrapod condition. The reason for the evolutionary movement of the posterior nostril from the nose to lip, however, is not well understood.
https://en.wikipedia.org/wiki?curid=38046595
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The main task of this institution is to equip graduates with knowledge and skills for individual managing of small family business in the area of biotechnology. This Faculty is the only one of its kind in the country. The higher education activities of the Faculty of Biotechnical Sciences are organized on different levels of higher education: graduate studies, postgraduate studies, and studies at doctoral level. The Faculty also undertakes fundamental, developmental and applicative research, and runs courses, seminars and workshops for staff and students. The education provided involves application of research results, supports the technical and technological development of the country, and encourages research aimed at creating the conditions for production of high quality food products.
https://en.wikipedia.org/wiki?curid=50497539
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The dangers of excess concentrations of nontoxic gases has been recognized for centuries within the mining industry. The concept of black damp (or "stythe") reflects an understanding that certain gaseous mixtures could lead to death with prolonged exposure. Early mining deaths due to mining fires and explosions were often a result of encroaching asphyxiant gases as the fires consumed available oxygen. Early self-contained respirators were designed by mining engineers such as Henry Fleuss to help in rescue efforts after fires and floods. While canaries were typically used to detect carbon monoxide, tools such as the Davy lamp and the Geordie lamp were useful for detecting methane and carbon dioxide, two asphyxiant gases. When methane was present, the lamp would burn higher; when carbon dioxide was present, the lamp would gutter or extinguish. Modern methods to detect asphyxiant gases in mines led to the Federal Mine Safety and Health Act of 1977 in the United States which established ventilation standards in which mines should be "ventilated by a current of air containing not less than 19.5 volume per centum of oxygen, not more than 0.5 volume per centum of carbon dioxide".
https://en.wikipedia.org/wiki?curid=7276747
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Pseudoexfoliation syndrome, often abbreviated as PEX and sometimes as PES or PXS, is an aging-related systemic disease manifesting itself primarily in the eyes which is characterized by the accumulation of microscopic granular amyloid-like protein fibers. Its cause is unknown, although there is speculation that there may be a genetic basis. It is more prevalent in women than men, and in persons past the age of seventy. Its prevalence in different human populations varies; for example, it is prevalent in Scandinavia. The buildup of protein clumps can block normal drainage of the eye fluid called the aqueous humor and can cause, in turn, a buildup of pressure leading to glaucoma and loss of vision (pseudoexfoliation glaucoma, exfoliation glaucoma). As worldwide populations become older because of shifts in demography, PEX may become a matter of greater concern.
https://en.wikipedia.org/wiki?curid=22481529
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In 2013 Auñon et al. showed that Casimir and Van der Waals interactions are a particular case of stochastic forces from electromagnetic sources when the broad Planck's spectrum is chosen and the wavefields are non-correlated. Addressing fluctuating partially coherent light emitters with a tailored spectral energy distribution in the optical range, this establishes the link between stochastic electrodynamics and coherence theory; henceforth putting forward a way to optically create and control both such zero-point fields as well as Lifshitz forces of thermal fluctuations. In addition, this opens the path to build many more stochastic forces on employing narrow-band light sources for bodies with frequency-dependent responses.
https://en.wikipedia.org/wiki?curid=1569292
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and an electro-optic/infrared (EO/IR) system, allowing it to operate as an independent standalone system without the need to operate as a battery with a separate FCS. Hisar-A has dual pulse solid propellant rocket motor, and so will be effective and highly maneuverable air targets, but 5 km altitude. However, Roketsan recently improved the missile and called it Hisar A+, although its range is still 15 km, the altitude has changed from 5 km to 8 km, and proximity fuse was changed from laser to RF by TÜBİTAK SAGE, and seeker is not changed and made by Aselsan with IIR, highly resistant to counter measure systems. Test video has shown that missile hit the target with second fire rocket motor and speed up of missile and detonated at proximity of the target, not a direct hit. Hisar-A have midcourse guidance with INS and RF data link, terminal guidance with IIR. Some platforms will be continue with Hisar-A, the others will use Hisar-A+, additionally some platforms will use both Hisar-A+ and Hisar-O missiles so will gain more flexibility.
https://en.wikipedia.org/wiki?curid=46398579
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The question particularly intrigued Harry Hammond Hess, a Princeton University geologist and a Naval Reserve Rear Admiral, and Robert S. Dietz, a scientist with the U.S. Coast and Geodetic Survey who first coined the term "seafloor spreading". Dietz and Hess (the former published the same idea one year earlier in "Nature", but priority belongs to Hess who had already distributed an unpublished manuscript of his 1962 article by 1960) were among the small number who really understood the broad implications of sea floor spreading and how it would eventually agree with the, at that time, unconventional and unaccepted ideas of continental drift and the elegant and mobilistic models proposed by previous workers like Holmes.
https://en.wikipedia.org/wiki?curid=24944
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Intel began integrating a line of GPUs onto motherboards under the Intel GMA brand in 2004. Being integrated onto motherboards (newer versions, such as those released with Sandy Bridge, are incorporated onto the same die as the CPU) these chips were not sold separately. Though the low cost and power consumption of Intel GMA chips made them suitable for small laptops and less demanding tasks, they lack the 3D graphics processing power to compete with contemporary Nvidia and AMD/ATI GPUs for a share of the high-end gaming computer market, the HPC market, or a place in popular video game consoles. In contrast, Larrabee was to be sold as a discrete GPU, separate from motherboards, and was expected to perform well enough for consideration in the next generation of video game consoles.
https://en.wikipedia.org/wiki?curid=11546286
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To fully characterize the physical world, the Stoics developed a theory of mixing in which they recognised three types of mixture. The first type was a purely mechanical mixture such as mixing barley and wheat grains together: the individual components maintain their own properties, and they can be separated again. The second type was a fusion, whereby a new substance is created leading to the loss of the properties of the individual components, this roughly corresponds to the modern concept of a chemical change. The third type was a commingling, or total blending: there is complete interpenetration of the components down to the infinitesimal, but each component maintains its own properties. In this third type of mixture a new substance is created, but since it still has the qualities of the two original substances, it is possible to extract them again. In the words of Chrysippus: "there is nothing to prevent one drop of wine from mixing with the whole ocean". Ancient critics often regarded this type of mixing as paradoxical since it apparently implied that each constituent substance be the receptacle of each other. However to the Stoics, the "pneuma" is like a force, a continuous field interpenetrating matter and spreading through all of space.
https://en.wikipedia.org/wiki?curid=23008428
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Clinical diagnosis based on orofacial clefts and lip pits typically occurs shortly after birth. Certain defects may be difficult to diagnose, particularly a submucous cleft palate. This form of CP may not be detected except through finger palpation, as the mucosa covering the palate is intact, but the muscles underneath have lost their proper attachments. Feeding problems, impaired speech, and hearing loss are symptoms of a submucous cleft palate. Furthermore, approximately 15% of VWS cases with orofacial clefts, in the absence of prominent lip pits, cannot be easily distinguished from non-syndromic forms of orofacial clefting. Therefore, it is very important to closely examine these patients as well as their relatives for lip pits, especially when there is a family history of mixed clefting, in order to make the VWS diagnosis. Dentists may also play an important role in diagnosing cases not detected at birth, as they detect hypodontia commonly associated with VWS. The
https://en.wikipedia.org/wiki?curid=2260123
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Also included in the 2008 revision of the HEOA were provisions requiring action by U.S. colleges and universities to combat illegal file-sharing. Following significant lobbying by the Motion Picture Association of America (MPAA) and Recording Industry Association of America (RIAA), the additions to the HEOA of 2008 included requirements that all U.S. colleges and universities (1) release an annual disclosure to students regarding copyright laws and associated campus policies, (2) a written plan, submitted to the Department of Education, to combat copyright abuse using one or more technology-based deterrents, and (3) an offer to students of alternatives to illegal downloading. Significant controversy surrounded the inclusion of anti-P2P legislation into HEOA of 2008, resulting in a letter from a number of leaders in higher education.
https://en.wikipedia.org/wiki?curid=4927364
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A somewhat controversial application of psychopharmacology is "cosmetic psychiatry": persons who do not meet criteria for any psychiatric disorder are nevertheless prescribed psychotropic medication. The antidepressant bupropion is then prescribed to increase perceived energy levels and assertiveness while diminishing the need for sleep. The antihypertensive compound propranolol is sometimes chosen to eliminate the discomfort of day-to-day anxiety. Fluoxetine in nondepressed people can produce a feeling of generalized well-being. Pramipexole, a treatment for restless leg syndrome, can dramatically increase libido in women. These and other off-label lifestyle applications of medications are not uncommon. Although occasionally reported in the medical literature, no guidelines for such usage have been developed. There is also a potential for the misuse of prescription psychoactive drugs by elderly persons, who may have multiple drug prescriptions.
https://en.wikipedia.org/wiki?curid=45621
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Tokenomics, also known as Token economics, is the study of parameters that determine the characteristics of cryptocurrencies (cryptos) or cryptographic tokens to create economic value. Both cryptocurrency and tokens are the subclasses of digital assets that use the technology of cryptography. Crypto is the native currency of a blockchain, and it is developed directly by the blockchain protocol. Tokens are created through a blockchain-based organization or application. For example, Ether (ETH) is the native crypto of Ethereum, while Axie Infinity Shards (AXS), the governance tokens of game Axie Infinity, lives on Ethereum, and users can use them to play games. In both cases, tokenomics act as an incentive mechanism and monetary policy of the supply and demand of certain crypto or token. Tokenomics rule how and when a new crypto or token should be generated or removed from the system. Once the tokenomics is written into a smart contract, the system is automated.
https://en.wikipedia.org/wiki?curid=71908188
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By Lenz's law, an eddy current creates a magnetic field that opposes the change in the magnetic field that created it, and thus eddy currents react back on the source of the magnetic field. For example, a nearby conductive surface will exert a drag force on a moving magnet that opposes its motion, due to eddy currents induced in the surface by the moving magnetic field. This effect is employed in eddy current brakes which are used to stop rotating power tools quickly when they are turned off. The current flowing through the resistance of the conductor also dissipates energy as heat in the material. Thus eddy currents are a cause of energy loss in alternating current (AC) inductors, transformers, electric motors and generators, and other AC machinery, requiring special construction such as laminated magnetic cores or ferrite cores to minimize them. Eddy currents are also used to heat objects in induction heating furnaces and equipment, and to detect cracks and flaws in metal parts using eddy-current testing instruments.
https://en.wikipedia.org/wiki?curid=465008
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A risk management plan is a documented plan that describes the risks (adverse drug reactions and potential adverse reactions) associated with the use of a drug and how they are being handled (warning on drug label or on packet inserts of possible side effects which if observed should cause the patient to inform/see his physician and/or pharmacist and/or the manufacturer of the drug and/or the FDA, European Medicines Agency. The overall goal of a risk management plan is to assure a positive risk-benefit profile once the drug is (has been) marketed. The document is required to be submitted, in a specified format, with all new market authorization requests within the European Union (EU). Although not necessarily required, risk management plans may also be submitted in countries outside the EU. The risks described in a risk management plan fall into one of three categories: identified risks, potential risks, and unknown risks. Also described within a risk management plan are the measures that the Market Authorization Holder, usually a pharmaceutical company, will undertake to minimize the risks associated with the use of the drug. These measures are usually focused on the product's labeling and healthcare professionals. Indeed, the risks that are documented in a pre-authorization risk management plan will inevitably become part of the product's post-marketing labeling. Since a drug, once authorized, may be used in ways not originally studied in clinical trials, this potential "off-label use", and its associated risks, is also described within the risk management plan. Risk management plans can be very lengthy documents, running in some cases hundreds of pages and, in rare instances, up to a thousand pages long.
https://en.wikipedia.org/wiki?curid=1243554
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The United States 9/11 Commission has said that nuclear power plants were potential targets originally considered for the September 11, 2001 attacks. If terrorist groups could sufficiently damage safety systems to cause a core meltdown at a nuclear power plant, and/or sufficiently damage spent fuel pools, such an attack could lead to widespread radioactive contamination. The Federation of American Scientists have said that if nuclear power use is to expand significantly, nuclear facilities will have to be made extremely safe from attacks that could release massive quantities of radioactivity into the community. New reactor designs have features of passive safety, which may help. In the United States, the NRC carries out "Force on Force" (FOF) exercises at all Nuclear Power Plant (NPP) sites at least once every three years.
https://en.wikipedia.org/wiki?curid=4222539
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The pilot phase tested and compared existing methods to rigorously analyze a defined portion of the human genome sequence. It was organized as an open consortium and brought together investigators with diverse backgrounds and expertise to evaluate the relative merits of each of a diverse set of techniques, technologies and strategies. The concurrent technology development phase of the project aimed to develop new high throughput methods to identify functional elements. The goal of these efforts was to identify a suite of approaches that would allow the comprehensive identification of all the functional elements in the human genome. Through the ENCODE pilot project, National Human Genome Research Institute (NHGRI) assessed the abilities of different approaches to be scaled up for an effort to analyze the entire human genome and to find gaps in the ability to identify functional elements in genomic sequence.
https://en.wikipedia.org/wiki?curid=2140955
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Neonatal sidewinders engage in a remarkable behavioral homeothermy that has not been observed in any other type of snake. Following birth, the neonates mass together in their natal burrow. Most often, gravid females select an east-facing, small-diameter rodent burrow for giving birth. For the first week or so of their lives, neonatal sidewinders plug the entrance to this burrow during daylight hours, forming a dynamic multiple-individual mass that takes advantage of the hot exterior environment and the cool interior of the burrow to maintain an average aggregate temperature of 32 °C (the optimal temperature for shedding). The dynamic mass of neonates modifies the thermal environment at the burrow entrance such that the young can occupy a location that would ordinarily become lethally hot for an individual neonate (or even an adult). Because of the constant movements of the neonates, the aggregate assumes stable temperature properties reminiscent of a homeothermic organism (i.e., maintains tight temperature tolerance ± 2 °C).
https://en.wikipedia.org/wiki?curid=368350
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During 1952–1958, Allen was a science officer and then senior science officer at the Atomic Energy Research Establishment (AERE, Harwell). From 1958–1964, he was a consultant and the Brazilian National Nuclear Energy Commission (CNEN) Laboratory and a professor at the University of Rome in Italy. During 1964–1965, he was an assistant director of research at the University of Cambridge at the invitation of the engineer W. R. Hawthorne. He spent the major portion of his career as a Fellow of University College, Oxford during 1965–1996 (31 years). He was a Reader (1990–1996) and then Emeritus Professor of Engineering Science from 1996 in the Department of Engineering Science at Oxford, when he became an Emeritus Fellow of University College. In 1991, he was editor of the book "Gas Discharge Physics" with the theoretical physicist Yuri Raizer. He has also been a Visiting Professor in Physics at Imperial College London.
https://en.wikipedia.org/wiki?curid=71464266
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Mead's contributions have arisen from the application of basic physics to the development of electronic devices, often in novel ways. During the 1960s, he carried out systematic investigations into the energy behavior of electrons in insulators and semiconductors, developing a deep understanding of electron tunneling, barrier behavior and hot electron transport. In 1960, he was the first person to describe and demonstrate a three-terminal solid-state device based on the operating principles of electron tunneling and hot-electron transport. In 1962 he demonstrated that using tunnel emission, hot electrons retained energy when traveling nanometer distances in gold. His studies of III-V compounds (with W. G. Spitzer) established the importance of interface states, laying the groundwork for band-gap engineering and the development of heterojunction devices.
https://en.wikipedia.org/wiki?curid=684268
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The traditional method of applying the carbon to the surface of the iron involved packing the iron in a mixture of ground bone and charcoal or a combination of leather, hooves, salt and urine, all inside a well-sealed box (the "case"). This carburizing package is then heated to a high temperature but still under the melting point of the iron and left at that temperature for a length of time. The longer the package is held at the high temperature, the deeper the carbon will diffuse into the surface. Different depths of hardening are desirable for different purposes: sharp tools need deep hardening to allow grinding and resharpening without exposing the soft core, while machine parts like gears might need only shallow hardening for increased wear resistance.
https://en.wikipedia.org/wiki?curid=1557416
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In most texts on statistical mechanics the statistical distribution functions formula_1 in Maxwell–Boltzmann statistics, Bose–Einstein statistics, Fermi–Dirac statistics) are derived by determining those for which the system is in its state of maximum probability. But one really requires those with average or mean probability, although – of course – the results are usually the same for systems with a huge number of elements, as is the case in statistical mechanics. The method for deriving the distribution functions with mean probability has been developed by C. G. Darwin and Fowler and is therefore known as the Darwin–Fowler method. This method is the most reliable general procedure for deriving statistical distribution functions. Since the method employs a selector variable (a factor introduced for each element to permit a counting procedure) the method is also known as the Darwin–Fowler method of selector variables. Note that a distribution function is not the same as the probability – cf. Maxwell–Boltzmann distribution, Bose–Einstein distribution, Fermi–Dirac distribution. Also note that the distribution function formula_2 which is a measure of the fraction of those states which are actually occupied by elements, is given by formula_3 or formula_4, where formula_5 is the degeneracy of energy level formula_6 of energy formula_7 and formula_8 is the number of elements occupying this level (e.g. in Fermi–Dirac statistics 0 or 1). Total energy formula_9 and total number of elements formula_10 are then given by formula_11 and formula_12.
https://en.wikipedia.org/wiki?curid=51188793
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The Yeast Metabolome Database is a freely accessible, online database of >2000 small molecule metabolites found in or produced by Saccharomyces cerevisiae (Baker's yeast). The YMDB contains two kinds of information: 1) chemical information and 2) biochemical information. The chemical information in YMDB includes 2027 metabolite structures with detailed metabolite descriptions, extensive chemical classifications, synthesis information and observed/calculated chemical properties. It also contains nearly 4000 NMR, GC-MS and LC/MS spectra obtained from more than 500 different metabolites. The biochemical information in YMDB includes >1100 protein (and DNA) sequences and >900 biochemical reactions. The YMDB supports a wide variety of queries including text searches, chemical structure searches, sequence similarity searches and spectral similarity searches. This makes it particularly useful for metabolomic researchers who are studying yeast as a model organism or who are looking into optimizing the production of fermented beverages (wine, beer).
https://en.wikipedia.org/wiki?curid=1075211
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New Turkish energy policies from the Renewable Energies Act have attempted to encourage the growth of renewable energy cooperatives to keep up with growing energy demand and reduce dependency on energy imports. After their economic crisis in 2001, the government worked to remodel the energy market from a state-owned model to an entirely privatized system. System reforms made it possible for 49.8% of the electricity production to be sourced from renewables by the end of 2019. In 2020, there exist 46 cooperatives. While it is not a large number compared to countries in Europe, the government has enacted REC regulations that allow cooperatives of certain sizes to be exempt from establishing themselves as a legal company and obtaining licenses. They can therefore avoid much of the regulations that licensed energy actors face. By 2023, the Republic of Turkey’s Ministry of Energy and Natural Resources (MENR) aims to increase shares of renewable energy sources by 30%.
https://en.wikipedia.org/wiki?curid=65691512
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AT is particularly useful as a lens in qualitative research methodologies (e.g., ethnography, case study). AT provides a method of understanding and analyzing a phenomenon, finding patterns and making inferences across interactions, describing phenomena and presenting phenomena through a built-in language and rhetoric. A particular activity is a goal-directed or purposeful interaction of a subject with an object through the use of tools. These tools are exteriorized forms of mental processes manifested in constructs, whether physical or psychological. As a results the notion of tools in AT is broad and can involve stationary, digital devices, library materials, or even physical meeting spaces. AT recognizes the internalization and externalization of cognitive processes involved in the use of tools, as well as the transformation or development that results from the interaction.
https://en.wikipedia.org/wiki?curid=628450
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Coriolis force was discovered by Gaspard-Gustave de Coriolis in 1832. By the end of the nineteenth century, Coriolis force had become a common phrase in meteorological literature. Coriolis force is classified as a fictitious force that is applied to objects that are in rotation. When applied to perception, this occurs when a person's head is moved out of alignment during a spin. If individuals are spinning to the left along their y-axis and then push their head forward, that will bring their heads out of alignment and make it subject to Coriolis force and resultant effect. The manifestation of this effect is that the individuals will feel like their heads are tilting to their left. This can cause nausea, disorientation, and motion sickness. These feelings of discomfort arise in the body when the signals being sent by the vestibular system and visual system are not in agreement, i.e. the eyes may be telling the body that one is not moving, but the vestibular system's fine-tuned senses are detecting and communicating the opposite.
https://en.wikipedia.org/wiki?curid=18025863
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The title, won by Piquet for the BMW-powered Brabham team of Bernie Ecclestone, was the first-ever won by a turbocharged engine. By 1983, the dispute between FISA and FOCA had been resolved and although FOCA emerged with the stronger hand, the teams had seen the writing on the wall. Renault had proven in 1979 and 1980 that turbo-charged engines were a more efficient means of getting more performance from the powertrain with the FIA regulations. The turbo cars were faster on almost all of the high speed (Hockenheim, Österreichring, Monza, Silverstone) and high-altitude tracks (Interlagos, Kyalami), but by 1982, the turbo cars were fastest just about everywhere. The 1982 season made it obvious to all the competing Formula One teams that turbocharged engines were the way to go if anyone wanted to be competitive in Formula 1. By 1983, the reliability of the turbo-charged engines had been ironed out and made more reliable, and in 1984, only Tyrrell still struggled on with the old DFV engines. 1983 also saw the last non-championship Formula One race: The 1983 Race of Champions at Brands Hatch, won by reigning World Champion Keke Rosberg in a Williams-Ford/Cosworth in a close fight with American Danny Sullivan.
https://en.wikipedia.org/wiki?curid=640098
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Anisotropy of liquid crystals is a property not observed in other fluids. This anisotropy makes flows of liquid crystals behave more differentially than those of ordinary fluids. For example, injection of a flux of a liquid crystal between two close parallel plates (viscous fingering) causes orientation of the molecules to couple with the flow, with the resulting emergence of dendritic patterns. This anisotropy is also manifested in the interfacial energy (surface tension) between different liquid crystal phases. This anisotropy determines the equilibrium shape at the coexistence temperature, and is so strong that usually facets appear. When temperature is changed one of the phases grows, forming different morphologies depending on the temperature change. Since growth is controlled by heat diffusion, anisotropy in thermal conductivity favors growth in specific directions, which has also an effect on the final shape.
https://en.wikipedia.org/wiki?curid=17973
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In the same field of applications, a major study on the accuracy, computational cost and parallel performance of the FPM was carried out in (Ortega, Oñate, Idelsohn & Flores, 2014b). There, the FPM was compared with an equivalent Finite Element-based solver, which provided a standard for assessing both, the characteristics of the meshless solver and its suitability to address practical applications. Some simplifications of the FPM technique were proposed in this work to improve efficiency and reduce the performance gap with FEM. Then, grid convergence studies using a wing-body configuration were conducted. The results showed comparable accuracy and performance, revealing the FPM competitive with respect to its FEM counterpart. This is important because meshless techniques are often considered impractical due to the poor efficiency of the initial implementations.
https://en.wikipedia.org/wiki?curid=50991882
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The coronal heating problem in solar physics relates to the question of why the temperature of the Sun's corona is millions of kelvins versus the thousands of kelvins of the surface. Several theories have been proposed to explain this phenomenon but it is still challenging to determine which of these is correct. The problem first emerged when Bengt Edlen and Walter Grotrian identified Fe IX and Ca XIV lines in the solar spectrum. This led to the discovery that the emission lines seen during solar eclipses are not caused by an unknown element called "coronium" but known elements at very high stages of ionization. The comparison of the coronal and the photospheric temperatures of 6,000K, leads to the question of how the 200 times hotter coronal temperature can be maintained. The problem is primarily concerned with how the energy is transported up into the corona and then converted into heat within a few solar radii.
https://en.wikipedia.org/wiki?curid=7839
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From a pragmatic viewpoint of the kind often ascribed to James, defining on a particular occasion whether a particular belief can rightly be said to be both true and justified is seen as no more than an exercise in pedantry, but being able to discern whether that belief led to fruitful outcomes is a fruitful enterprise. Peirce emphasized fallibilism, considered the assertion of absolute certainty a barrier to inquiry, and in 1901 defined truth as follows: "Truth is that concordance of an abstract statement with the ideal limit towards which endless investigation would tend to bring scientific belief, which concordance the abstract statement may possess by virtue of the confession of its inaccuracy and one-sidedness, and this confession is an essential ingredient of truth." In other words, any unqualified assertion is likely to be at least a little wrong or, if right, still right for not entirely the right reasons. Therefore one is more veracious by being Socratic, including recognition of one's own ignorance and knowing one may be proved wrong. This is the case, even though in practical matters one sometimes must act, if one is to act at all, with a decision and complete confidence.
https://en.wikipedia.org/wiki?curid=246176
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Helmut Schelp, who had taken over from Mauch, felt that the BMW 003 and Junkers Jumo 004 would reach production at about the same power levels long before either of the Heinkel projects would be ready, and cancelled both of them. He outlined a new development plan with three engine classes; the 003 and 004 were "Class 1" engines of under 1000 kg thrust suitable for small fighters, but only really useful in twin-engine designs. Schelp was much more interested developing a "Class II" engine of 1000–2000 kg, larger designs able to power a full-sized fighter design with a single engine. Schelp was also interested in seeing one of his own pet projects, the diagonal compressor, adopted. Schelp had earlier convinced Heinkel to put some effort into another pet project of his, a twin-compressor single-turbine turboprop, but had given up on this and instead offered Heinkel his new concept as a consolation prize.
https://en.wikipedia.org/wiki?curid=2732309
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In 1925, the Royal Air Force (RAF) tested the ability of air supremacy in isolation from other warfare forms during their first independent action in Waziristan. The operation, that later came to be known as Pink's War after Wing Commander Richard Pink in charge, used only air warfare in a combination of air attack and "air blockade" over 54 days to force militant tribes to surrender. The campaign was successful in defeating the tribes with two deaths for the RAF, but contemporary critics were not entirely convinced of its use in isolation; Commander-in-Chief, India General Sir Claud Jacob stated that "satisfactory ... the results of these operations have been, I am of [the] opinion that a combination of land and air action would have brought about the desired result in a shorter space of time, and next time action has to be taken, I trust that it will be possible to employ the two forces in combination".
https://en.wikipedia.org/wiki?curid=537478
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Types II and III (or mixed or variant) cryoglobulinemic disease may also present with symptoms and signs of blood hyperviscosity syndrome and deposition of cryoglobulins within blood vessels but also include those attributable to cryoglobulinemic vasculitis. "Meltzer's triad" of palpable purpura, joint pain, and generalized weakness occurs in ≈33% of patients presenting with type II or type III disease. One or more skin lesions including palpable purpura, ulcers, digital gangrene, and areas of necrosis occur in 69-89% of these mixed disease cases (see attached photograph); less common findings include painful peripheral neuropathy (often manifesting as mononeuritis multiplex in 19-44% of cases), kidney disease (primarily membranoproliferative glomerulonephritis (30%), joint pain (28%), and, less commonly, dry eye syndrome, Raynaud phenomenon (i.e., episodic painful reductions in blood flow to the fingers and toes). While the glomerulonephritis occurring in mixed disease appears to be due to inflammatory vasculitis, the glomerulonephritis occurring in type I disease appears due to the interruption of blood flow. The hematological, infectious, and autoimmune diseases underlying type II cryoglobulinemic disease and the infectious and autoimmune diseases underlying type III cryoglobulinemic disease are also critical parts of the disease's clinical findings.
https://en.wikipedia.org/wiki?curid=1565362
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