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Nuclear plants were designed to withstand earthquakes, hurricanes, and other extreme natural events. But deliberate attacks involving large airliners loaded with fuel, such as those that crashed into the World Trade Center and Pentagon, were not considered when design requirements for today's fleet of reactors were determined. It was in 1972 when three hijackers took control of a domestic passenger flight along the east coast of the U.S. and threatened to crash the plane into a U.S. nuclear weapons plant in Oak Ridge, Tennessee. The plane got as close as 8,000 feet above the site before the hijackers' demands were met.
https://en.wikipedia.org/wiki?curid=40528380
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A factory must choose looms and shedding mechanisms to suit its commercial requirements. As a rule the more warp control required the greater the expense. So it is not economical to purchase Jacquard machines if one can make do with a dobby mechanism. As well as the capital expense, the Jacquard machines are more costly to maintain as they are complex and require higher skilled personnel; an expensive design system is required to prepare the designs for the loom, and possibly a card-cutting machine. Weaving is more costly since Jacquard mechanisms are more likely to produce faults than dobby or cam shedding. Also, the looms will not run as quickly and down-time will increase because it takes time to change the continuous chain of cards when a design changes. For these reasons it is best to weave larger batches with mechanical Jacquards.
https://en.wikipedia.org/wiki?curid=16225
215,851
1,078,004
Since the SCN is responsible for mediating the production of melatonin by the pineal gland, it creates a feedback loop that regulates the production of melatonin according to the master circadian clock. As was discussed previously, the MT receptor is largely thought of as the major player in sleep-promotion and the MT receptor is most strongly linked to phase shifting activity. Both major subtypes of the melatonin receptor are expressed in relatively large amounts in the SCN which allow it to both regulate sleep-wake cycles and induce phase shifting in response to natural light-dark cycles. This functional diversity of melatonin receptors helps give the SCN the ability to not only keep near 24-hour time and entrain to an exactly 24-hour period, but also regulate, among other factors, wakefulness and activity throughout this cycle.
https://en.wikipedia.org/wiki?curid=8258942
1,077,449
182
In 1920, he became a Foreign Member of the Royal Netherlands Academy of Arts and Sciences. In 1922, he was awarded the 1921 Nobel Prize in Physics "for his services to Theoretical Physics, and especially for his discovery of the law of the photoelectric effect". While the general theory of relativity was still considered somewhat controversial, the citation also does not treat even the cited photoelectric work as an "explanation" but merely as a "discovery of the law", as the idea of photons was considered outlandish and did not receive universal acceptance until the 1924 derivation of the Planck spectrum by S. N. Bose. Einstein was elected a Foreign Member of the Royal Society (ForMemRS) in 1921. He also received the Copley Medal from the Royal Society in 1925.
https://en.wikipedia.org/wiki?curid=736
182
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The diagnosis of neutropenia is done via the low neutrophil count detection on a complete blood count. Generally, other investigations are required to arrive at the right diagnosis. When the diagnosis is uncertain, or serious causes are suspected, bone marrow biopsy may be necessary. A bone marrow biopsy can identify abnormalities in myelopoesis contributing to neutropenia such as the stage of arrest in the development of myeloid progenitor cells. Bone marrow biopsies can also be used to monitor the development of myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) in patients with chronic neutropenia (especially in those with severe congenital neutropenia (SCN) which carries a higher risk of MDS and AML)). Other investigations commonly performed: serial neutrophil counts for suspected cyclic neutropenia, tests for antineutrophil antibodies, autoantibody screen (and investigations for systemic lupus erythematosus), vitamin B and folate assays. Rectal examinations are usually not performed due to the increased risk of introducing bacteria into the blood stream and the possible development of rectal abscesses.
https://en.wikipedia.org/wiki?curid=235419
320,365
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The institute also has a profound political history. Between 1964 and 1969, during the worst years of the military dictatorship, 33 professors were eliminated, as well as a good number of students. Many high-ranking officials, including three presidents - Getúlio Vargas and João Goulart - as well as the majority of the history, philosophy and social sciences teachers in smaller universities throughout the state were educated in the institution. The climate of intellectual debate and analysis of public issues has also been important in training students (often with scholarships and/or student apprenticeships) to work for non-governmental and governmental organisations which contribute to the critical reflection and planning of development programs.
https://en.wikipedia.org/wiki?curid=889448
1,233,738
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Burroughs Corporation, a maker of adding machines and computers, developed the Panaplex display in the early 1970s. The Panaplex display, generically referred to as a gas-discharge or gas-plasma display, uses the same technology as later plasma video displays, but began life as a seven-segment display for use in adding machines. They became popular for their bright orange luminous look and found nearly ubiquitous use throughout the late 1970s and into the 1990s in cash registers, calculators, pinball machines, aircraft avionics such as radios, navigational instruments, and stormscopes; test equipment such as frequency counters and multimeters; and generally anything that previously used nixie tube or numitron displays with a high digit-count. These displays were eventually replaced by LEDs because of their low current-draw and module-flexibility, but are still found in some applications where their high brightness is desired, such as pinball machines and avionics.
https://en.wikipedia.org/wiki?curid=175859
288,642
1,810,224
The common names for this insect in many languages follow the binomial name and mention that it has twenty-four spots, but in English there is great variation in how this is written, with little consensus over the use of words or numerals, capitalisation, placement of hyphens and whether to use "spot", "spotted", "point" or "pointed"; "ladybird", "ladybird beetle" or "ladybug". There is even disagreement about the spelling of the Latin ""vigintiquatuorpunctata"" with some authoritative UK lists preferring a double "t": ""vigintiquattuopunctata"". For ease it is often written ""Subcoccinella 24-punctata"". Given the multitude of name formations, it is probably best to use just the genus ""Subcoccinella"" when carrying out a web search for information about this insect to avoid missing texts that use variant spellings - it's the only species in the genus. In the US it is also known as the "Alfalfa Lady Beetle", though rarely found on alfalfa in North America.
https://en.wikipedia.org/wiki?curid=41621168
1,809,202
1,683,088
Exposure therapy’s effectiveness in rodents is increased by the administration of Vorinostat, Entinostat, TSA, sodium butyrate, and VPA, all known histone deacetylase inhibitors. Several studies in the past two years have shown that in humans, Vorinostat and Entinostat increase the clinical effectiveness of exposure therapy as well, and human trials using the drugs successful in rodents are planned. In addition to research on the effectiveness of HDAC inhibitors, some researchers have suggested that histone acetyltransferase activators might have a similar effect, although not enough research has been completed to draw any conclusions. However, none of these drugs are likely to be able to replace exposure therapy or other cognitive behavioral therapy methods. Rodent studies have indicated that administration of HDAC inhibitors without successful exposure therapy actually worsens anxiety disorders significantly, although the mechanism for this trend is unknown. The most likely explanation is that exposure therapy works by a learning process, and can be enhanced by processes which increase neural plasticity and learning. However, if a subject is exposed to a stimulus which causes anxiety in such a way that their fear does not decrease, compounds which increase learning may also increase re-consolidation, ultimately strengthening the memory.
https://en.wikipedia.org/wiki?curid=42647878
1,682,145
1,564,288
In the United States in the 1960s up until the early 70s, Harvard Medical School, Neurosurgeon Vernon H. Mark at Boston City Hospital, and his associate, Professor of Psychiatry Dr Frank R. Ervin, carried out research on electroencephalographic recordings on the skull (EEG), cerebral surface, as well as deep structures of the brain. They studied patients with EEG abnormalities and overt seizure disorders associated with uncontrolled aggression and found that many of these patients had abnormalities of the brain causing their temporal lobe epilepsy or psychomotor seizures. Their treatment was stimulation or ablation of the amygdala, unilaterally or bilaterally. Approximately 20 amygdalotomies were performed, with many patients improved but not necessarily cured. This work in psychosurgery became highly controversial and as the debate on psychosurgery heated up in the 70s it was abandoned.
https://en.wikipedia.org/wiki?curid=38574601
1,563,401
1,762,854
Hunting causes the room temperature to constantly fluctuate, creating a major cost to clients with poor environmental quality and increased maintenance. Over three-quarters of complaints to managers are of a thermal sensation nature. These complaints are rarely due to inter-individual differences in preferred temperature but, instead, to increases as temperature deviation widens. The solution that more than two-thirds of building managers use to answer this type of complaint is to change the set-point. By lowering the set-point by an average of 1 °C in a cooling system we increase its energy usage by up to 10%. The solution to the problems of "hunting" and overflow in chilled water systems lies in the use of pressure independent control valves.
https://en.wikipedia.org/wiki?curid=28596905
1,761,861
305,957
During the Second World War, aerodynamic issues became sufficiently understood for work on a range of production-representative prototypes to commence. In Nazi Germany, the Horten brothers were keen proponents of the flying wing configuration, developing their own designs around it - uniquely for the time using Prandtl's birdlike "bell-shaped lift distribution". One such aircraft they produced was the Horten H.IV glider, which was produced in low numbers between 1941 and 1943. Several other late-war German military designs were based on the flying wing concept, or variations of it, as a proposed solution to extend the range of otherwise very short-range of aircraft powered by early jet engines.
https://en.wikipedia.org/wiki?curid=191711
305,793
1,595,244
The symptoms of isolated 17,20-lyase deficiency, in males, include pseudohermaphroditism (i.e., feminized, ambiguous, or mildly underdeveloped (e.g., micropenis, perineal hypospadias, and/or cryptorchidism (undescended testes)) external genitalia), female gender identity, and, in non-complete cases of deficiency where partial virilization occurs, gynecomastia up to Tanner stage V (due to low androgen levels, which results in a lack of suppression of estrogen); in females, amenorrhoea or, in cases of only partial deficiency, merely irregular menses, and enlarged cystic ovaries (due to excessive stimulation by high levels of gonadotropins); and in both sexes, hypergonadotropic hypogonadism (hypogonadism despite high levels of gonadotropins), delayed, impaired, or fully absent adrenarche and puberty with an associated reduction in or complete lack of development of secondary sexual characteristics (sexual infantilism), impaired fertility or complete sterility, tall stature (due to delayed epiphyseal closure), eunuchoid skeletal proportions, delayed or absent bone maturation, and osteoporosis.
https://en.wikipedia.org/wiki?curid=35934236
1,594,346
1,060,356
Before the telecom market collapsed in the early 2000s, such companies represented 45% of Thorlabs' business. Due to a liberal return policy, at least one quarter during the market crash, Thorlabs actually received more product from returns than it shipped. However, the company was able to quickly adapt and survived its worst year with only an 18% drop in overall revenue. In 2003 and 2004, Thorlabs began to expand its operations into Europe, acquiring companies based in Germany, Sweden, and the United Kingdom. The company had a product line of 9,000 and estimated annual sales of $50 million in 2004.
https://en.wikipedia.org/wiki?curid=45477128
1,059,805
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Reductive dechlorination has been investigated for bioremediation of polychlorinated biphenyls (PCB) and chlorofluorocarbons (CFC). The reductive dechlorination of PCBs is performed by anaerobic microorganisms that utilize the PCB as an electron sink. The result of this is the reduction of the "meta" site, followed by the "para" site, and finally the "ortho" site, leading to a dechlorinated product. In the Hudson River, microorganisms effect dechlorination over the course of weeks. The resulting monochlorobiphenyls and dichlorobiphenyls are less toxic and more easily degradable by aerobic organisms compared to their chlorinated counterparts. The prominent drawback that has prevented the widespread use of reductive dechlorination for PCB detoxification and has decreased its feasibility is the issue of the slower than desired dechlorination rates. It has been suggested that bioaugmentation with DF-1 can lead to enhanced reductive dechlorination rates of PCBs through stimulation of dechlorination. Additionally, high inorganic carbon levels do not affect dechlorination rates in low PCB concentration environments.
https://en.wikipedia.org/wiki?curid=971594
1,714,476
1,202,789
The earliest genetic methods for assessing "Symbiodinium" diversity relied on low-resolution molecular markers that separated the genus into a few evolutionarily divergent lineages, referred to as "clades". Previous characterizations of geographic distribution and dominance have focused on the clade-level of genetic resolution, but more detailed assessments of diversity at the species level are needed. While members of a given clade may be ubiquitous, the species diversity within each clade is potentially large, with each species often having different ecological and geographic distributions related to their dispersal ability, host biogeography, and external environmental conditions. A small number of species occur in temperate environments where few symbiotic animals occur. As a result, these high latitude associations tend to be highly species specific.
https://en.wikipedia.org/wiki?curid=11375187
1,202,146
774,463
Unemployment did not exist officially in the socialist planned economies, though there were people between jobs and a fraction of unemployable people as a result of illness, disability or other problems, such as alcoholism. The proportion of people changing jobs was between 6 and 13 percent of the labour force a year according to employment data during the 1970s and 1980s in Central and Eastern Europe and the USSR. Labour exchanges were established in the USSR in 1967 to help enterprises re-allocate workers and provide information on job vacancies. Compulsory unemployment insurance schemes operated in Bulgaria, Eastern Germany and Hungary but the numbers claiming support as a result of losing their job through no fault of their own numbered a few hundred a year.
https://en.wikipedia.org/wiki?curid=43069513
774,047
730,197
As a result of a new emphasis on observing, classifying, and cataloging nature, 16th-century natural philosophers in Europe began to establish extensive collections of fossil objects (as well as collections of plant and animal specimens), which were often stored in specially built cabinets to help organize them. Conrad Gesner published a 1565 work on fossils that contained one of the first detailed descriptions of such a cabinet and collection. The collection belonged to a member of the extensive network of correspondents that Gesner drew on for his works. Such informal correspondence networks among natural philosophers and collectors became increasingly important during the course of the 16th century and were direct forerunners of the scientific societies that would begin to form in the 17th century. These cabinet collections and correspondence networks played an important role in the development of natural philosophy.
https://en.wikipedia.org/wiki?curid=7991116
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MGA is frequently used as an appetite stimulant to promote weight gain. The direct mechanism of appetite enhancement is unclear, but it is known that MGA induces a variety of downstream changes to cause the effect, including stimulation of the release of neuropeptide Y in the hypothalamus, neurosteroid-like modulation of calcium channels in the ventromedial hypothalamus, and inhibition of the secretion of proinflammatory cytokines including interleukin 1α, interleukin 1β, interleukin 6, and tumor necrosis factor α, all of which have been implicated in facilitation of appetite. Increased levels of insulin-like growth factor 1 (IGF-1) may also be involved, specifically in its anabolic effects. Studies of MGA in elderly patients who experience weight loss are limited and of poor quality with most showing minimal or no weight gain, with no nutritional or clinically significant beneficial outcomes observed. In patients who take MGA, one in 12 will have an increase in weight.
https://en.wikipedia.org/wiki?curid=6657950
710,235
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Between the 12 and 20 August 1944 the Allies launched an offensive to close the Falaise pocket at Chambois, from where remnants of the German army were attempting to escape. Vimoutiers was near the junction of Anglo-Canadian and Polish forces in the north and US and French forces in the south. On 21 August 1944, along with other German tanks (Panthers, Panzer IIIs and IVs and other Tigers) and a variety of military vehicles, the Tiger was heading out of the Falaise pocket to a fuel dump at the Chateau de l'Horloge in Ticheville during the final days of the Battle of Normandy. It is thought the tank ran out of fuel on RN 179 just after leaving Vimoutiers. The tank's crew abandoned the tank and set off two explosive charges on the vehicle, which left the tank's turret immobilized and damaged the engine decking, leaving distinct cracking on the thick armoured plates. About sixty German armoured vehicles were abandoned in the vicinity of Vimoutiers.
https://en.wikipedia.org/wiki?curid=38294328
1,057,173
1,860,961
Brownell was an undergraduate student in biology at Cornell University. She moved to The Scripps Research Institute, where she worked toward a Master's degree. She joined Stanford University as a doctoral researcher, studying small heat shock proteins (sHSPs) as anti-inflammatory therapeutics. She found that certain sHSPs were protective in mouse models of multiple sclerosis and stroke. In particular, deficiency of Alpha B crystallin (CRYAB) is associated with worse disease outcome in stroke patients. She simultaenously earned a Master's degree in education at Stanford University. After completing her doctorate, Brownell joined the faculty at Stanford as a lecturer in biology and developed inquiry-based lab courses. She worked in both the San Francisco State University and University of Washington as a postdocotral researcher in science education.
https://en.wikipedia.org/wiki?curid=70460840
1,859,892
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Measurement of annual parallax was the first reliable way to determine the distances to the closest stars. In the second quarter of the 19 century, technological progress reached to the level which provided sufficient accuracy and precision for stellar parallax measurements. The first successful stellar parallax measurements were done by Thomas Henderson in Cape Town South Africa in 1832-1833, where he measured parallax of one of the closest stars ― alpha Centauri. Few years later ― 1835-1836 ― followed Friedrich Georg Wilhelm von Struve at Dorpat (nowadays Tartu) university observatory, who measured the distance of Vega and published his results in 1837. Friedrich Bessel, a friend of Struve, carried out an intense observational campaign in 1837-1838 at Koenigsberg Observatory for the star 61 Cygni using a heliometer, and published his results in 1838. Henderson published his results in 1839, after returning from South Africa.
https://en.wikipedia.org/wiki?curid=202661
898,643
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SimuMCAT is a free Java application program that simulates a multidimensional computer adaptive test (MCAT). The user can select from five different MCAT item selection procedures (Volume, Kullback-Leibler information, Minimize the error variance of the linear combination, Minimum Angle, and Minimize the error variance of the composite score with the optimized weight). Two exposure control approaches are possible: the traditional Sympson-Hetter approach and a maximum exposure control approach. It is also possible to implement content constraints using the Priority Index method. Different stopping rules are implemented with fixed-length test and varying-length test. The user specifies true examinee ability, item pools, and item selection procedures, and the program outputs selected items with item responses and ability estimates. Bayesian and non-Bayesian methods can be specified by the user. The examinees’ ability and item pools can also be created from the program by the user specified distributions.
https://en.wikipedia.org/wiki?curid=21073228
1,982,339
492,178
Guidance for the Corporal consisted of a complex system of internal and ground guidance. During the initial launch phase, inertial guidance kept the missile in a vertical position and pre-set guidance steered it during its launch. The ground guidance system was a modified World War II SCR-584 radar which tracked the missile's position, as well as its slant range. This information was sent to an analog computer which calculated the trajectory and any necessary correction to hit the target. A Doppler radar was used to accurately measure the missile's velocity, and this information was also used in the trajectory calculation. The Doppler radar was also used to send the final range correction and warhead arming command after the missile re-entered the atmosphere. Transponder beacons were used in the missile to provide a return signal for tracking at maximum range. The vulnerability of the Corporal system was of concern from the beginning of the weapon program. Electronic anticountermeasures were addressed over the length of the program and would have been greatly improved in Corporal III. Though a variety of warheads from high explosive and fragmentation to chemical had been developed the warhead which the missile was equipped was the W-7 (Mk.7).
https://en.wikipedia.org/wiki?curid=1956534
491,924
2,241,803
The Museum was chartered under the laws of the state of Texas on June 2, 1967 and granted its tax exemption certificate in August of that year. On October 7, 1968, the Junior League Museum Board entered into a leaning agreement with the City of McAllen for a 5,000 square foot building. Shortly after, a Board of Trustees was appointed and by-laws were adopted. The initial funding came from donations by local business firms, civic organizations, and individuals. An Executive Director was employed in June 1969, and building renovations were completed. The Museum was dedicated and formally opened to the public on October 26, 1969. On July 4, 1976, a new building was constructed and completed as a Bicentennial Project, and the Museum moved to 1900 Nolana, where it currently resides.
https://en.wikipedia.org/wiki?curid=12116813
2,240,532
1,346,095
Automated chilled mirror devices provide significantly more repeatable results, but these measurements can be affected by contaminants that may compromise the mirror's surface. In many instances it is important to incorporate an effective filtration system that prepares the gas for analysis. On the other hand, filtration may alter the gas composition slightly and filter elements are subject to clogging and saturation. Advances in technology have led to analyzers that are less affected by contaminants and certain devices can also measure the dew point of water that may be present in the gas. One recent innovation is the use of spectroscopy to determine the nature of the condensate at dewpoint. Another device user laser interferometry to register extremely tenuous amounts of condensation. It is asserted that these technologies are less affected by interference from contaminants. Another source of error is the speed of the cooling of the mirror and the measurement of the temperature of the mirror when the condensation is detected. This error can be minimized by controlling the cooling speed, or having a fast condensation detection system.
https://en.wikipedia.org/wiki?curid=8892966
1,345,354
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Following the conclusion of the 1946-47 school year, the Minnesota state legislature approved a bill authorizing the transfer of the Duluth State Teachers College to the University of Minnesota system with the school to be known as the University of Minnesota, Duluth Branch or UMD. With an expanded schedule of meets against conference rivals as well as local colleges, the 1948 UMD golf team won two of three triangular meets against Duluth Junior College and Superior State College, defeated Bemidji Teachers College and Saint Cloud Teachers College in another triangular meet and beat Eveleth Junior College in a dual meet. The squad entered the 1948 conference loop more prepared to challenge for the title than in 1947. Improving on the previous year, the team finished third at the TCC golf championship held at Mankato County Club. Jerry Chessen shot a 74 for 18 holes and finished one stroke out of a playoff for individual medalist honors.
https://en.wikipedia.org/wiki?curid=50172482
2,107,284
1,923,379
The Electronic Systems Center served into five decades as the Air Force's organization for developing and acquiring Command and Control (C2) systems. As of December 2004, ESC managed approximately two hundred programs ranging from secure communications systems to mission planning systems. ESC had an annual budget of over $3 billion and more than eighty-seven hundred personnel. In addition to the Air Force, ESC works with other branches of the United States Department of Defense, the North American Aerospace Defense Command (NORAD), the National Aeronautics and Space Administration (NASA), the Federal Aviation Administration (FAA), the North Atlantic Treaty Organization (NATO), and foreign governments.
https://en.wikipedia.org/wiki?curid=1250357
1,922,276
1,190,895
A total of 15 out of 20 Indianapolis 500 winners praised the inaugural running of the United States Grand Prix at the Indianapolis Motor Speedway. 1985 Indianapolis 500 winner Danny Sullivan heralded the race organisers for their efforts, "Tony George has done a phenomenal job of integrating it into (the schedule) and not losing the integrity of the current Indianapolis 500 track. I think this shows this is the place it (Formula One) should be." 1993 winner and double Formula One World Champion Emerson Fittipaldi believed that it would create a new era of Formula One motor racing in the United States. Fittipaldi's view was backed up by 1998 winner Eddie Cheever who thought the event would inspire more Americans to move into Formula One. The Grand Prix was awarded the Race Promoters' Trophy at the FIA Prize Giving Awards in Monte Carlo in December 2000.
https://en.wikipedia.org/wiki?curid=1123406
1,190,261
2,130,654
The majority of studies on the prognosis of patients treated for LGMS have focused on short-term (i.e. one-year) follow-up times. One study of 49 patients (age range: 29.5–64.5; average age: 46.2 years; median age: 51.0 years) treated for LGFS reported overall survival percentages at 3 and 5 years of 75.0% and 71.6%, respectively. Their disease-specific survival (i.e. excluding deaths from causes unrelated to LGMS) at 3 and 5 years after treatment were 80.0% and 76.3%, respectively. These patients were treated with surgery in 93.9% of cases and radiotherapy in 26.5% of cases but no patients had lymph node metastasis and only 1 case had distant metastases (the presence of lymph node and distant tissue metastasis was unknown in 8 patients). The study of 96 individuals treated for LFMS reported 1, 3, 5, and 10-year disease-specific survival percentages of 88%, 77%, 70%, and 59%, respectively. Patient age >60 years was the only factor that clearly reduced survival times in this study (disease specific survival times for patients 60 years old or younger and >60 years were 167.1 and 92.5 months, respectively).
https://en.wikipedia.org/wiki?curid=69495466
2,129,429
1,355,723
The most precious and most needed resource of all is water, and in some parts of the world, that is a very expensive resource to obtain. The most obvious areas that conflict may arise over disputes for water supplies would be in the desert, but at the moment oil is the most valuable liquid in the Middle East. However, oil will not always be there, and if those people are going to survive, they must have water. Several times, countries that are upriver have threatened to build dams across the rivers in order to cut off the country down river, starving that particular country of its water supply. This has been the case with both the Nile and the River Jordan, and the results in both cases have been the same: the countries that are down river have threatened retaliation if such an event should occur. As our global warming trend continues, our weather patterns will continue to shift, and that means that some places will fall into a severe drought. These people may become desperate when they do not have the resources to obtain water if such a disaster should occur.
https://en.wikipedia.org/wiki?curid=1794929
1,354,975
212,627
Later, in February 2018, the "Yomiuri Shimbun" reported that Japan was planning to acquire 40 F-35Bs, the Short Take-off and Vertical Landing (STOVL) variant of the Lockheed Martin Lightning II Joint Strike Fighter (JSF), which could be operated from the "Izumo" class with some modifications to the ships. It was estimated that each "Izumo"-class carrier could operate 12 or more F-35B aircraft. In March that same year, the ruling Liberal Democratic Party called upon the Japanese government to develop its own aircraft carriers and operate F-35B aircraft, which has been thought to include refitting the "Izumo" class. Defence Minister Takeshi Iwaya announced on 27 November 2018 that Japan is considering buying F-35Bs within an order for an additional 100 F-35 aircraft, and as a consequence modifying both "Izumo"-class helicopter carriers to operate F-35B were also considered.
https://en.wikipedia.org/wiki?curid=25300829
212,519
1,522,334
Within the field of limnology, there are more specific areas of study. One of those areas of study is ecology, particularly the ecology of water systems. The ecology of water systems focuses on the organisms that live in freshwater environments and how they are affected by changes in their habitat. For example, a limnologist specializing in ecology could study how chemical or temperature changes in a body of water inhibit or support new organic growth. Another aspect that they may examine are the effects of a nonnative species on native populations of aquatic life. Most ecological limnologists conduct their studies in laboratory settings, where their hypotheses can be tested, verified, and controlled. Another area of study under limnology is biology. Limnologists who specialize in the biology field only study the living aquatic organisms that are present in a certain freshwater environment. They aim to understand various aspects of the organisms, such as their history, their life cycles, and their populations. These scientists study living organisms in order to support the proper management of fresh bodies of water and their ecosystems.
https://en.wikipedia.org/wiki?curid=17622112
1,521,473
797,724
Music has been a prominent subject in schools and other learning institutions in Europe for many centuries. Such early institutions as the Sistine Chapel Choir and the Vienna Boys Choir offered important early models of choral learning, while the Paris Conservatoire later became influential for training in wind band instruments. Several instructional methods were developed in Europe that would later impact other parts of the world, including those affiliated with Zoltan Kodaly, Carl Orff, Émile Jaques-Dalcroze, and ABRSM, to name but a few. Notable professional organizations on the continent now include the Europe regional branch of the International Society for Music Education, and the European Association of Conservatoires. In recent decades, Central, Southern, and Eastern Europe have tended to successfully emphasize classical music heritage, while the Nordic countries have especially promoted popular music in schools.
https://en.wikipedia.org/wiki?curid=2025792
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"Overwatch"s diversity also extends to other character facets. Blizzard has said that some of the characters have LGBT identities; Metzen said that the inclusion of LGBT characters was not "to be a data point or feel contrived in any way", but instead to have these identities "play out organically". Tracer was the first identified as one of the LGBT characters via one of the promotional online comics. Blizzard said on this reveal "as with any aspect of our characters' backgrounds, their sexuality is just one part of what makes our heroes who they are. From the very beginning of our work on Tracer's story, it just felt right to make this an aspect of her character." Blizzard reiterated their goal to have a diverse cast with Tracer's reveal, stating, "from the beginning, we've wanted the universe of "Overwatch" to feel welcoming and inclusive, and to reflect the diversity of our players around the world." Additional lore released in January 2019 revealed that Soldier: 76 had been in a same-sex relationship earlier in this life, making him the second LGBT character on the roster. Similarly, the character of Symmetra is considered autistic by the development team, with Kaplan saying, "we think she does a great job of representing just how awesome someone with autism can be".
https://en.wikipedia.org/wiki?curid=55762533
1,367,819
165,884
Hemostasis can be achieved in various other ways if the body cannot do it naturally (or needs help) during surgery or medical treatment. When the body is under shock and stress, hemostasis is harder to achieve. Though natural hemostasis is most desired, having other means of achieving this is vital for survival in many emergency settings. Without the ability to stimulate hemostasis the risk of hemorrhaging is great. During surgical procedures, the types of hemostasis listed below can be used to control bleeding while avoiding and reducing the risk of tissue destruction. Hemostasis can be achieved by chemical agent as well as mechanical or physical agents. Which hemostasis type used is determined based on the situation.
https://en.wikipedia.org/wiki?curid=501973
165,799
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Early construction after the expansion of Dubai as a global city paid little attention to traditional Islamic architecture and concerns for the environment were not considered. In the late 1980s and early 1990s, glass towers became prominent in the city of Dubai, all of which required enormous amounts of electricity to keep cool. Recently, builders and architects have become aware of both Arabic heritage and environmental concerns, leading to more harmonious development overseen by Dubai’s rulers in the last 20 years. Efficient heat resistant materials are increasingly used in construction, combined with traditional Arabic designs. This can be seen in the buildings for which Dubai has attracted worldwide attention for, including the Burj Khalifa and Burj Al Arab.
https://en.wikipedia.org/wiki?curid=60447339
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Bradman was given another life at 108 when he advanced two metres down the pitch to Jim Laker and missed, but Evans fumbled the stumping opportunity. Australia reached tea at 1/292 having added 171 during the session. Morris was eventually dismissed for 182, having partnered Bradman in a stand of 301 in 217 minutes. This brought Miller to the crease with 46 runs still required. He struck two boundaries and helped take the score to 396 before falling with eight runs still needed. Harvey came in and got off the mark with a boundary that brought up the winning runs. This sealed an Australian victory by seven wickets, setting a new world record for the highest successful Test run-chase, with Bradman unbeaten on 173 with 29 fours in only 255 minutes.
https://en.wikipedia.org/wiki?curid=21051201
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In 1969-70, due to the proposed development of the Wilderness Road site, a new Meteorological Enclosure had to be found. Late in 1969 a site was found on land east of the Whiteknights Lakes and adjoining Bridges Hall.  A quick changeover took place to the new enclosure for records to start, unbroken, on January 1, 1970. Due to difficulties with the re-erection of the wind tower, it was some months before the Munro wind direction and speed measurements moved to the site's final location. The site was managed by various University departments, but was taken over by the Department of Meteorology in 1987, and merged with their small research site, established in the early 1970s. From 2008 the site became known as the Reading University Atmospheric Observatory, reflecting its wider range of uses at a time when new university development plans threatened its existence.
https://en.wikipedia.org/wiki?curid=18112383
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Saccadic suppression is responsible for maintaining a continuous, stable, visual world by reducing visual sensitivity to events occurring before, during and after a saccade. The more complex the background on which the stimulus is presented, the larger the suppression. The increase in saccadic suppression can lead to a decrease in detection of change in the visual field. Saccadic suppression can be linked to the phenomenon of change blindness, in which individuals lack the ability to detect small or large changes within an environment without the aid of directed attention. There are two types of saccadic suppression, with the first concerning the detection of light spot flashes during saccades. The lower the spatial frequency, meaning fewer objects in the visual field of the light flashes, the stronger the saccadic suppression. With fewer items in the visual field it is easier for saccadic suppression to occur. The higher the spatial frequency, which involves more complex objects within the visual field, the less likely there will be saccadic suppression. The second type concerns the detection of image displacement or a change in an image during eye movement. A displacement between saccades would not be detected because the movement of the eye eliminates the signal for the detection of the displacement. The location of the target forms an image feature that is used by the visual system to establish space constancy, which maintains the location of an object in space. Target blanking is used to study visual stability, space constancy and the content of information transferred across saccades. Blanking a target after a saccade eliminates an attempt to make a second saccade, resulting in the visual system failing to find the target information. Stability and constancy across the saccades is broken, as a result, image displacements become easier to detect when blanking occurs during or right after the saccade.
https://en.wikipedia.org/wiki?curid=31148473
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Gilovich's research in the alleged "hot hand" effect, or the belief that success in a particular endeavor, usually sports, will likely be followed by further success, has been particularly influential. A paper he wrote with Amos Tversky in 1985 became the benchmark on the subject for years. Some of the research from the 1985 paper has been contested recently, with a new journal article arguing that Gilovich and his coauthors themselves fell victim to a cognitive bias in interpreting the data from the original study. Specifically, that in a truly random situation, a hit would be expected to be followed by another hit less than 50 percent of the time, but if one hit followed another at 50 percent, that would be evidence for the hot hand. Gilovich responded, "The larger the sample of data for a given player, the less of an issue this is...Because our samples were fairly large, I don’t believe this changes the original conclusions about the hot hand."
https://en.wikipedia.org/wiki?curid=881902
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While the College's geographic size has changed little since 1596, an additional range was added to the original E-shaped buildings in the early 17th century and the appearance of the whole College was changed significantly in the 1820s and 1830s, under the leadership of the Master at the time, William Chafy. By the early 19th century, the buildings' original red brick was unfashionable and the hall range was suffering serious structural problems. The opening up of coal mines on estates left to the College in the 18th century provided extra funds which were to be devoted to providing a new mathematical library and accommodation for Mathematical Exhibitioners. As a result, the exterior brick was covered with a layer of cement, the existing buildings were heightened slightly, and the architectural effect was also heightened, under the supervision of Sir Jeffry Wyatville.
https://en.wikipedia.org/wiki?curid=212179
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Physical organic chemistry often entails the identification of molecular structure, dynamics, and the concentration of reactants in the course of a reaction. The interaction of molecules with light can afford a wealth of data about such properties through nondestructive spectroscopic experiments, with light absorbed when the energy of a photon matches the difference in energy between two states in a molecule and emitted when an excited state in a molecule collapses to a lower energy state. Spectroscopic techniques are broadly classified by the type of excitation being probed, such as vibrational, rotational, electronic, nuclear magnetic resonance (NMR), and electron paramagnetic resonance spectroscopy. In addition to spectroscopic data, structure determination is often aided by complementary data collected from X-Ray diffraction and mass spectrometric experiments.
https://en.wikipedia.org/wiki?curid=11304514
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In case a ship is underway, a fast rudder change will not only initiate a heading change, but it will also cause the ship to roll. For some ships such as frigates, this effect is so large that it can be used by a control algorithm to simultaneously steer the ship while reducing its roll motions. Such a system is usually referred to as "Rudder Roll Stabilisation System". Its effectiveness can be as good as that of stabiliser fins. However, that depends on the ship speed (higher is better) and various ship design aspects such as position, size and quality of the rudder positioning system (behaves as fast as a stabiliser fin). Also important is how quickly the ship will respond to rudder motions with roll motions (quick is better) and rate of turn (slow is better). Despite the high costs of high-quality steering gear and strengthening of the ship's stern, this stabilisation option offers better economics than stabiliser fins. It requires fewer installations, is less vulnerable and it causes less drag. Even better, the required high-quality components provide excellent steering properties also for those periods when roll reduction is not required and a significant reduction of underwater noise. Known navy ships with this stabilisation solution are F124 (Germany), M-fregat and LCF (both of Dutch Navy).
https://en.wikipedia.org/wiki?curid=10675964
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The F-4C Phantom II aircraft arrived on 18 November 1979, and the Tail Code "FW" (Fort Wayne) was adopted by the 122d TFW. The unit flew this new aircraft to Balikesir Air Base, Turkey in 1983 for exercise "Coronet Crown," and once again in 1986 for exercise "Coronet Cherokee". In 1986 the F-4Cs were replaced with more up-to-date F-4E Phantom IIs. In 1989, the squadron again deployed to Southwest Asia for exercise "Coronet Brave" in conjunction with "Bright Star". The unit continued its standard of excellence by supporting Operation Desert Shield and Desert Storm with deployments to Saudi Arabia by the Security Police, January through June 1991, and to Tyndall Air Force Base, Florida, by the Tactical Hospital in September/October 1991.
https://en.wikipedia.org/wiki?curid=17261034
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North American distribution boards are generally housed in sheet metal enclosures, with the circuit breakers positioned in two columns operable from the front. Some panelboards are provided with a door covering the breaker switch handles, but all are constructed with a "dead front"; that is to say the front of the enclosure (whether it has a door or not) prevents the operator of the circuit breakers from contacting live electrical parts within. Busbars carry the current from incoming line ("hot") conductors to the breakers, which are secured to the bus with either a "bolt-on" connection (using a threaded screw) or a "plug-in" connection using a retaining clip. "Panelboards" are more common in commercial and industrial applications and employ bolt-on breakers. Residential and light commercial panels are generally referred to as "load centers" and employ plug-in breakers. The neutral conductors are secured to a neutral bus using screw terminals. The branch circuit bonding conductors are secured to a terminal block attached directly to the panelboard enclosure, which is itself grounded.
https://en.wikipedia.org/wiki?curid=751771
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Two professors from Stanford University Paul Milgrom and Robert Wilson successfully improved auction theory and invented several new auction formats, including Simultaneous Multiple Round Auctions (SMRA). This format combines the benefit of both English Auctions (open-outcry) and Sealed Bid auctions. SMRAs are deemed to solve the problem by Federal Communications Commission (FCC). Due to FCC wanting to sell all of its telecommunication frequency slots by using traditional auction, however, it will eventually turn out to give away the licenses for free or end up with a telecom monopoly in the United States. Eventually, simultaneous multiple round auctions have generated $20 billion in US dollars profit for the US government.
https://en.wikipedia.org/wiki?curid=5827247
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DeWitte was born in New Hampshire and raised in New Mexico and California. As a youth, she had surgery to insert a metal rod to correct scoliosis of the spine. She graduated from Santa Rosa Junior College with her Associates Degree in 1996 and from Sonoma State University with her Bachelor of Arts degree in 1999 before enrolling at Pennsylvania State University for her graduate degrees. During her doctorate degree, DeWitte received a Dissertation Research Grant from the Wenner-Gren Foundation and the National Science Foundation to investigate the mortality patterns of the Black Death. In order to conduct this research, she drew from a sample of Black Death skeletons from the East Smithfield cemetery in London. DeWitte finished her dissertation, "The Paleodemography of the Black Death 1347-1351," in 2006.
https://en.wikipedia.org/wiki?curid=70161939
2,028,198
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It is only known from flowering individual plants seen at a number of locations in southeastern Java, until 2017 all of them in the Jember Regency. The first place it was collected was in 1902 at the forestry research station ("boschproefstation") at low elevations on the eastern flanks of a hill called Puger Watangan, not far from the beach ("Pantai Puger") near the village of . It had perhaps also been seen on neighbouring Mount Sadeng in Jember Regency in the 1910s, but was thereafter not seen for many decades, until a flowering plant was discovered in Meru Betiri National Park (see photo above), also in the Jember Regency, but somewhat further down the coast to the east, and stretching to Banyuwangi Regency. The Indonesian experts Zuhud and Hikmat rediscovered the species here in 1987. Interviews with locals living around the park has uncovered many more localities, including one outside the park's borders. As of 2012 the species is now known to occur at at least 25 different localities throughout the park, distributed primarily along the coast and the main river, but in a few occasions more inland.
https://en.wikipedia.org/wiki?curid=20683449
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Cryoglobulins are proteins, principally immunoglobulins, that circulate in the blood, precipitate at temperatures <37 °C (98.6 °F), and re-solubilize upon restoring physiological blood temperatures. They are made and secreted into the blood as a result of underlying pathological conditions viz., inflammation, infection, or malignancies. Rarely, cryoglobulinemia (i.e. essential cryoglobulinemia) occurs in patients without these or other identifiable conditions. Non-essential cryoglobulonemia is classified into three types. Type 1 cryoglobulinemia (10-25% of cases) involves a circulating myeloma protein, typically IgM or IgG but in rare case reports IgA. The condition is associated with Waldenström macroglobulinemia or multiple myeloma in ~40% of type I cases, the MGUS or smoldering predecessors to these diseases in ~44% of type I cases, and other B cell lymphoproliferative disorders in ~16% of type I cases. Type II cryglobulinemia (50-60% of cases) involves circulating IgM myeloma protein with rheumatoid factor activity and therefore bound to polyclonal IgG and protein components of the blood complement system; hepatitis C virus and, far more rarely, hepatitis B virus or human immunodeficiency virus infections are the major causes of this cryoglobulinemia. Type III cryoglobulinemia (15-30% of cases) involves circulating polyclonal IgM protein with rheumatoid factor activity bound to polyclonal IgG and blood complement components; autoimmune diseases and, less commonly, hepatitis virus C infection or lymphoproliferative disorders are the cause of this type of croglobulinemia. Only types I and II are defined as plasma cell dyscrasias.
https://en.wikipedia.org/wiki?curid=17475959
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It was in the late 19th and early 20th century, that phycology became a recognized field of its own. Men such as Friedrich Traugott Kützing continued the descriptive work. In Japan, beginning in 1889, Kintarô Okamura not only provided detailed descriptions of Japanese coastal algae, he also provided comprehensive analysis of their distribution. Although R. K. Greville published his "Algae Britannicae" as early as 1830, it was not until 1902 with the publication of "A Catalogue of the British Marine Algae" by Edward Arthur Lionel Batters that the systematic correlation of records, extensive distribution mapping and the development of identification keys began in earnest. In 1899-1900, Anna Weber-Van Bosse, a Dutch Phycologist travelled on the Siboga expedition and later in 1904, published "The Corallinaceae of the Siboga-expedition".
https://en.wikipedia.org/wiki?curid=90347
703,024
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On 4 May 1906, Koizumi arrived in Mostyn, North Wales, aboard the SS "Romsford". He then travelled to Liverpool, where he took up the post of instructor at the Kara Ashikaga School of Jujitsu. He then travelled south to London, where he collaborated with former Bartitsu Club instructor Sadakazu Uyenishi, who was operating his own jujitsu school in Piccadilly Circus. During this period, Koizumi also taught jujitsu at the London Polytechnic and for the Royal Naval Volunteer Reserve. After several months, he set off for New York, arriving in May 1907. He secured work in the Newark Public Service Railway Company. After a few years, dissatisfied with life in the USA, he returned to England. He tried to start an electric lighting company in Vauxhall Road, London, but lacked sufficient funds. In January 1912, he set up a lacquer ware studio in Ebury Street, London.
https://en.wikipedia.org/wiki?curid=1690360
1,709,906
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The third named "Amphicoelias" species, "A. fragillimus", was known only from a single, incomplete tall neural arch, either last or second to last in the series of back vertebrae. Based only on an illustration published in 1878, this vertebra would have measured tall in life. However, it has been argued that the scale bar in the published description contained a typographical error, and the fossil vertebra was in fact only tall. In addition to this vertebra, Cope's field notes contain an entry for an "[i]mmense distal end of femur”, located only a few tens of meters away from the giant vertebra. It is likely that this undescribed leg bone belonged to the same individual animal as the neural spine, but it was never collected or described. In 2018, "A. fragillimus" was given its own genus, "Maraapunisaurus", and reclassified as a primitive rebbachisaurid.
https://en.wikipedia.org/wiki?curid=20597704
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The missile seeker can be slaved to the Helmet Mounted Display (HMD), allowing the pilot to track a target beyond the aircraft's radar scan envelope using the missile's high off-boresight capability, achieved by the pilot turning his head towards the target to lock-on, better known as "look and shoot". The missile can then be launched and can immediately pull extreme g-force to reverse its course to engage a target behind the aircraft, sometimes called an "over-the-shoulder". Engage modes include Lock-On After Launch (LOAL) capability to engage targets outside its seeker's acquisition range, and Lock-On Before Launch (LOBL) capability where the target is identified and designated before launch. The two colour thermal imaging technology and a laser proximity fuse fitted on the missile provide multiple Electronic counter-countermeasures (ECCM) techniques with targeting algorithms including advanced spatial filtering techniques and velocity profiling.
https://en.wikipedia.org/wiki?curid=9891281
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In November 2013, with orders and commitments totaling 259 aircraft from Lufthansa, Emirates, Qatar Airways, and Etihad Airways, Boeing formally launched the 777X program, the third generation of the 777 (not to be confused with the 777-X variants, the -200LR and -300ER, which are the second generation of the aircraft), with two models: the 777-8 and 777-9. The 777-9 is a further stretched variant with a capacity of over 400 passengers and a range of over , whereas the 777-8 is slated to seat approximately 350 passengers and have a range of over . Both models are to be equipped with new generation GE9X engines and feature new composite wings with folding wingtips. The first member of the 777X family, the 777-9, was projected to enter service in 2020 at the time of the program announcement. By the mid-2010s, the 777 had become prevalent on the longest flights internationally and had become the most widely used airliner for transpacific routes, with variants of the type operating over half of all scheduled flights and with the majority of transpacific carriers.
https://en.wikipedia.org/wiki?curid=89260
9,213
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In August 1964, Ontario Hydro decided to build the first large-scale nuclear power plant in Canada at Pickering on Lake Ontario, only 30 kilometres from downtown Toronto to save on transmission costs. To reduce cost the reactors share safety systems including containment and the emergency core cooling system. Pickering A station started operations in 1971 at a cost of $716 million (1965). It was followed by the Bruce A station, built in 1977 at a cost of $1.8 billion on the same site as the Douglas Point reactor. Beginning in 1983 four B reactors were added to the existing Pickering units, with all of them sharing the same common infrastructure as the A reactors. The final cost for these four new reactors was $3.84 billion (1986). Likewise for $6 billion, four new reactors were added to the Bruce site starting in 1984, but in a separate building with their own set of shared infrastructure for the new reactors. After a loss of coolant accident occurred at Pickering reactor A2 in August 1983, four of the reactors had their pressure tubes replaced between 1983 and 1993 at a cost of $1 billion (1983).
https://en.wikipedia.org/wiki?curid=3778479
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Doctor's degrees normally take four additional years of full-time study to complete. Requirements for obtaining a doctor's degree include taking additional advanced courses, passing an oral qualifying exam and submitting a longer doctoral dissertation which must represent a significant original contribution to knowledge in the field to which the dissertation topic is related. That contrasts with master's thesis, which, in addition to being usually shorter than doctoral dissertations, are not required to include creation of new knowledge or revision/reinterpretation of older views/theories. The doctoral dissertation is examined in a final oral exam before a panel of at least two members (in the state of São Paulo the preferred number is five, while the other regions prefer three members), usually including one or two external examiners from another university or research institute.
https://en.wikipedia.org/wiki?curid=167241
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Henry Sylvester Jacoby (born 1857, died 1955) was an American educator, born at Springtown, Bucks County, Pennsylvania, He was graduated from Lehigh University in 1877 and during the season of 1878 was connected with the topographical corps of the Pennsylvania Geological Survey. During 1879–85, he was chief draftsman in the United States Engineer's Office in Memphis, Tenn. In 1886, he returned to Lehigh, where until 1890 he was instructor of civil engineering; he then accepted a call to Cornell University, where in 1897 he became professor of bridge engineering. Professor Jacoby was a fellow of the American Association for the Advancement of Science and in 1901 presided over the Section on Engineering, with the rank of vice-president, and was president of the Society for the Promotion of Engineering Education in 1915–16. Besides numerous papers on his specialty of bridge engineering, he was the author of:
https://en.wikipedia.org/wiki?curid=9385173
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Meta-analyses show that high scores on the personality domain neuroticism are a strong predictor for the development of mood disorders. A number of authors have also suggested that mood disorders are an evolutionary adaptation ("see also evolutionary psychiatry"). A low or depressed mood can increase an individual's ability to cope with situations in which the effort to pursue a major goal could result in danger, loss, or wasted effort. In such situations, low motivation may give an advantage by inhibiting certain actions. This theory helps to explain why negative life incidents precede depression in around 80 percent of cases, and why they so often strike people during their peak reproductive years. These characteristics would be difficult to understand if depression were a dysfunction.
https://en.wikipedia.org/wiki?curid=52316
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Over time, neuroscience researchers have recognized that brain regions do not operate in isolation. In fact, the synchronization of firing rates of neurons across different brain regions helps mediate the integration and processing of information across the brain. Thus, studies relating neural activation in single regions to personality measures and associated sociocognitive functioning ignore information about how personality and sociocognitive functioning relate to neural activations across multiple regions in the brain. For example, it is unlikely that neural activation in a single brain region is unilaterally associated with individual differences in personality measures, such as the tendency to down-regulate negative emotions. However, the functional connectivity, or the synchronization of neural activity, between two brain regions can be related to individual differences in personality and sociocognitive functioning. For example, one study found that in an emotion regulation task, coupling of neural responses in the amygdala and the prefrontal cortex was significantly associated with more successful regulation of negative emotions. Other studies shown that neuroticism is associated with relatively low functional connectivity between amygdala and anterior cingulate cortex during a variety of tasks, such as viewing negative emotional stimuli and during a classical conditioning reward task.
https://en.wikipedia.org/wiki?curid=37691915
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Cognos initially attempted to move to the Intel platform in 1988 with the DOS-based "PowerHouse PC". While the product was used by numerous partners to build bespoke applications for small to medium-sized customers it was not entirely unsuccessful at that time. However, Cognos eventually produced Axiant (c.1995), which ported PowerHouse-like syntax to an Intel-based Microsoft Windows visual development environment and linked it to SQL aware DBMS running on these machines. The radical changes wrought by the PC revolution, which began just at the time "PowerHouse" was introduced, eventually brought down the cost of host computers to such an extent that high-priced software development tools such as PowerHouse became unattractive to customers.
https://en.wikipedia.org/wiki?curid=4313670
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Disposable tags cost a matter of cents and may have been embedded during manufacture. More sophisticated systems are available, which are more difficult to circumvent. These solutions tend to be product category specific as in the case of high value added electronics and consumables; consequently they are more expensive. Examples are "Safers", transparent secure boxes that completely enclose the article to be protected, Spiders that wrap around packaging and Electronic Merchandise Security Systems that allow phones and tablets to be used securely in the store before purchase. All of these require specific detachers or electronic keys at the point-of-sale desk. They have the advantages of being reusable, strong visual deterrents to potential theft.
https://en.wikipedia.org/wiki?curid=1802422
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The WMA, the Korean Medical Association, and the Chinese Medical Association reached an agreement in 1998 that these practices were undesirable and that they would jointly investigate them with a view to stopping them; however, in 2000, the Chinese withdrew their cooperation. Amnesty International claimed to have strong evidence that the police, courts and hospitals were complicit in the organ trade, facilitated by the use of mobile execution chambers, or "death vans". Amnesty speculated that this profitable trade might explain China's refusal to consider abolishing the death penalty, which is used on between 1,770 (official figure) and 8,000 (Amnesty estimates) prisoners annually. Corpses are typically cremated before relatives or independent witnesses can view them, fuelling suspicions about the fate of internal organs.
https://en.wikipedia.org/wiki?curid=6497079
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From their completion through mid-World War II, the four "Gridley"s formed Destroyer Division 11 of Destroyer Squadron 6. Based at Pearl Harbor in 1941, the squadron was at sea escorting on 7 December 1941, then was dispersed among carrier task forces during the Marshalls-Gilberts raids of early 1942. While "Gridley" and "McCall" were sent to the Aleutians in June, "Maury" was at the battles of the Coral Sea and Midway, and then went to Guadalcanal, where she participated in the Battle of Tassafaronga in November. "Craven" and "McCall" escorted convoys to Guadalcanal during this period. The four ships of the class were reunited to screen for the New Georgia landings in June 1943; then Maury was at the Battle of Kolombangara in July, and with "Craven" for the Battle of Vella Gulf in August. "Maury" then received a Presidential Unit Citation for the period 1 February 1942 to 6 August 1943. "Gridley" and "Maury" were at the Gilbert Islands/Tarawa invasion in November of that year. All four destroyers operated together in the Marshalls and Marianas campaigns (including the Battle of the Philippine Sea) through mid-1944, and, less "Craven" (which went to the Atlantic), continued screening escort carriers off the Philippines (including the Battle of Leyte Gulf) and Formosa into 1945.
https://en.wikipedia.org/wiki?curid=2840535
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The discoveries of americium and curium under the hypothesis that they resembled the lanthanides prompted Seaborg to propose the concept of an actinide series to his colleagues in 1944 – with the central premise being similarity to the lanthanides and filling of f orbitals. Despite its apparent correctness, they did not recommend Seaborg to submit a communication to Chemical and Engineering News, fearing that it was a radical idea that would ruin his reputation. He nevertheless submitted it and it gained widespread acceptance; new periodic tables thus placed the actinides below the lanthanides. Following its acceptance, the actinide concept proved pivotal in the groundwork for discoveries of heavier elements, such as berkelium in 1949. The actinide concept explained some of the observed properties of the first few actinides, namely the presence of +4 to +6 oxidation states, and proposed hybridization of the 5f and 6d orbitals, whose electrons were shown to be loosely bound in these elements. It also supported experimental results for a trend towards +3 oxidation states in the elements beyond americium.
https://en.wikipedia.org/wiki?curid=6151908
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Under a small grant from the International Council on Clean Transportation (icct), Daniel K Carder of West Virginia University (WVU) uncovered on-board software "cheats" that VW had installed on some diesel passenger vehicles (Dieselgate scandal). The only way the discovery could have been made was by a non-programmed, random, on-road evaluation - utilizing a PEMS device. VW is now liable for over US$14 billion in fines. In 2016, these latest developments led to a global resurgence of interest in smaller, lighter, integrated and cost-effective "non-1065" PEMS, similar to the demonstration on "MythBusters" 2011 Episode 171 of "Bikes and Bazookas", in which a non-1065 PEMS was used to establish the difference between car and motorcycle pollution.
https://en.wikipedia.org/wiki?curid=11108817
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In April 2012, Dark Horse began releasing a second eight-issue limited series entitled "Falling Skies: The Battle of Fitchburg", with Paul Tobin returning as writer and Juan Ferreyra returning as series artist. The digital comic was made available through both Dark Horse Comics and TNT via their respective websites. The story takes place chronologically between the first and second seasons of the television show and details a costly engagement occurring between the skitters and the 2nd Massachusetts Militia Regiment when the aliens surround the human forces at Fitchburg, Massachusetts. While not vital to the story of the television series, TNT and Dark Horse have stated that "Falling Skies: The Battle of Fitchburg" provides insight into the events leading up to the second season, and elaborates on how the characters got to where they are when the new season opens. As a companion to the comic, TNT released an audio series featuring the character John Pope, offering additional insight into the events detailed in the comic series.
https://en.wikipedia.org/wiki?curid=30214103
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Christiaan Huygens, Lord of Zeelhem, ( , , ; also spelled Huyghens; ; 14 April 1629 – 8 July 1695) was a Dutch mathematician, physicist, engineer, astronomer, and inventor, who is regarded as one of the greatest scientists of all time and a major figure in the Scientific Revolution. In physics, Huygens made groundbreaking contributions in optics and mechanics, while as an astronomer he is chiefly known for his studies of the rings of Saturn and the discovery of its moon Titan. As an engineer and inventor, he improved the design of telescopes and invented the pendulum clock, a breakthrough in timekeeping and the most accurate timekeeper for almost 300 years. An exceptionally talented mathematician and physicist, Huygens was the first to idealize a physical problem by a set of mathematical parameters, and the first to fully mathematize a mechanistic explanation of an unobservable physical phenomenon. For these reasons, he has been called the first theoretical physicist and one of the founders of modern mathematical physics.
https://en.wikipedia.org/wiki?curid=42127
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In 1913, Niels Bohr introduced the Bohr model of atomic structure, wherein electrons within atoms can only take on a series of discrete, rather than continuous, energies. This is another example of quantization. The Bohr model successfully explained the discrete nature of atomic spectral lines. In 1924, Louis de Broglie proposed the hypothesis of wave–particle duality, that microscopic particles exhibit both wave-like and particle-like properties under different circumstances. Uniting these scattered ideas, a coherent discipline, quantum mechanics, was formulated between 1925 and 1926, with important contributions from Max Planck, Louis de Broglie, Werner Heisenberg, Max Born, Erwin Schrödinger, Paul Dirac, and Wolfgang Pauli.
https://en.wikipedia.org/wiki?curid=25267
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"Gammarus roeseli" are a successful invasive species due to their high reproductive rate, tolerance to changing environmental conditions and unique anti-predation characteristics. "G. roeseli's" mechanism of invasion is still unknown but it is most likely due to human activities such as aquaculture or fish repopulation. "G. roeseli" were once used as a food source in commercial fisheries, so it is possible that some individuals escaped and were able to populate new areas. "G. roeseli" have the ability to easily attach their bodies to substrates by using the spines on its metasomes. These organisms are also able to survive out of water for several days at a time, making the transfer of "G. roeseli" feasible over land.
https://en.wikipedia.org/wiki?curid=10390006
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The entire spacecraft rotated to provide the necessary signal modulation. The four, fixed solar panels were designed to provide enough gyroscopic moment to stabilize rotation about the solar vector. This largely eliminated the need for attitude control. The instrument detectors were nine high-purity germanium crystals. Each was cooled to cryogenic temperatures by a mechanical cryocooler. Germanium provided not only detections by the photoelectric effect, but inherent spectroscopy through the charge deposition of the incoming ray. The crystals are housed in a cryostat, and mounted with low-conductivity straps. A tubular telescope structure formed the bulk of the spacecraft. Its purpose was to hold the collimators above the Ge crystals at known, fixed positions.
https://en.wikipedia.org/wiki?curid=1190663
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The Institute for Laboratory Animal Management (ILAM) is an AALAS educational program developed to provide instruction in management concepts that is applicable to the laboratory animal science industry and to enhance communication, team building, and networking among colleagues with mutual interests. Directors, managers, and supervisors of laboratory animal facilities have seen their roles grow more and more complex over the years, and they have found themselves in a unique profession. People in management positions must be able to interpret the social, political, and economic environments in which they operate and use administrative and technical skills to maintain and improve their animal care and use programs. The vast majority of people in these positions was trained in biologic and veterinary sciences and must find additional training in management skills to fulfill their administrative roles.
https://en.wikipedia.org/wiki?curid=10182721
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After the War, Herzfeld returned to the University of Vienna, however, the University was in such dire financial straits that he moved to Munich in 1919, with the intent of studying analytical chemistry and getting a job in the German chemical industry, which had a highly respected reputation. First, he was an assistant at the physico-chemical laboratory of Kasimir Fajans at Ludwig Maximilian University of Munich (LMU). However, once there, he found the challenge of theoretical physics more to his liking. He became Privatdozent for theoretical physics and physical chemistry at LMU, and therefore was much more associated with Arnold Sommerfeld, who was ordinarius professor for theoretical physics and Director of the Institute for Theoretical Physics – a prominent organization for the study of atomic and molecular structure. From 1925, until he left LMU in 1926, he was extraordinarius professor of theoretical physics. During this time, Linus Pauling did postdoctoral studies with him, and he was the thesis advisor for Walter Heitler, who got his doctorate in 1926. In 1925, Herzfeld published his book on kinetic theory and statistical mechanics, which became a graduate-level textbook in German-speaking universities.
https://en.wikipedia.org/wiki?curid=5383886
1,680,776
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The cosmological principle is first clearly asserted in the "Philosophiæ Naturalis Principia Mathematica" (1687) of Isaac Newton. In contrast to earlier classical or medieval cosmologies, in which Earth rested at the center of universe, Newton conceptualized the Earth as a sphere in orbital motion around the Sun within an empty space that extended uniformly in all directions to immeasurably large distances. He then showed, through a series of mathematical proofs on detailed observational data of the motions of planets and comets, that their motions could be explained by a single principle of "universal gravitation" that applied as well to the orbits of the Galilean moons around Jupiter, the Moon around the Earth, the Earth around the Sun, and to falling bodies on Earth. That is, he asserted the equivalent material nature of all bodies within the Solar System, the identical nature of the Sun and distant stars and thus the uniform extension of the physical laws of motion to a great distance beyond the observational location of Earth itself.
https://en.wikipedia.org/wiki?curid=173937
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It is quite clear that the structure of the enzyme, to be specific the active site, is very important in understanding the mechanism of reaction. For this reason, Rees and colleagues studied the enzyme-ligand complex to get a clear answer for the role of the zinc ion. These studies found that, in free enzyme, the zinc coordination number is five; the metal center is coordinated with two imidazole Nδ1 nitrogens, the two carboxylate oxygens of glutamate-72, and a water molecule to form a distorted tetrahedral. However, once ligand binds at the active site of carboxypeptidase A, this coordination number can vary from five to six. When bound to dipeptide glycyl-L-tyrosine, the amino nitrogen of the dipeptide and the carbonyl oxygen replaced the water ligand. This would yield a coordination number of six for the zinc in the carboxypeptidase A- dipeptide glycyl-L-tyrosine complex. Electron density maps gave evidence that the amino nitrogen occupies a second position near glutamate-270. The closeness of these two residues would result in a steric hindrance preventing the water ligand from coordinating with zinc. This would result in a coordination number of five. Data for both are substantial, indicating that both situations occur naturally.
https://en.wikipedia.org/wiki?curid=11213645
1,235,998
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Star charts of that period labeled it as the "Little Cloud". In 1612, the German astronomer Simon Marius gave an early description of the Andromeda Galaxy based on telescopic observations. Pierre Louis Maupertuis conjectured in 1745 that the blurry spot was an island universe. In 1764, Charles Messier cataloged Andromeda as object M31 and incorrectly credited Marius as the discoverer despite its being visible to the naked eye. In 1785, the astronomer William Herschel noted a faint reddish hue in the core region of Andromeda. He believed Andromeda to be the nearest of all the "great nebulae", and based on the color and magnitude of the nebula, he incorrectly guessed that it was no more than 2,000 times the distance of Sirius, or roughly . In 1850, William Parsons, 3rd Earl of Rosse made the first drawing of Andromeda's spiral structure.
https://en.wikipedia.org/wiki?curid=74331
20,448
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The formation of the Early Music Consort of London in the late 1960s has been credited with popularising the genre of Early music in UK and being main instigator of the British Early music revival of the late 20th century. Munrow was inspired by the "Alte Musik" movement that had already gained popularity in Germany, and sought to foster an interest in music of the Medieval and Renaissance eras among British audiences. Munrow collaborated with Christopher Hogwood, with whom he had studied at Pembroke College, Cambridge University in setting up a new specialist music group, initially called the Early Music Consort, but changed to The Early Music Consort of London, prior to their tour of America. It was essentially a small, versatile group optimised for touring purposes, but capable of being augmented by larger forces for recording purposes. The group's original line-up consisted of Munrow, a wind instrumentalist who played many different instruments; Hogwood playing keyboard, harp and percussion; Mary Remnant on fiddle, organ and tabor; Oliver Brookes on viol; Robert Spencer on lute; and the countertenor James Bowman. Later, another multi instrumentalist James Tyler replaced Robert Spencer and Mary Remnant left. A number of other singers also worked with the group such as the tenor Martyn Hill.
https://en.wikipedia.org/wiki?curid=11796930
1,580,236
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Simple schemes such as "send the message 3 times and use a best 2 out of 3 voting scheme if the copies differ" are inefficient error-correction methods, unable to asymptotically guarantee that a block of data can be communicated free of error. Advanced techniques such as Reed–Solomon codes and, more recently, low-density parity-check (LDPC) codes and turbo codes, come much closer to reaching the theoretical Shannon limit, but at a cost of high computational complexity. Using these highly efficient codes and with the computing power in today's digital signal processors, it is now possible to reach very close to the Shannon limit. In fact, it was shown that LDPC codes can reach within 0.0045 dB of the Shannon limit (for binary Additive white Gaussian noise (AWGN) channels, with very long block lengths).
https://en.wikipedia.org/wiki?curid=3474289
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Meanwhile, the return of the AIF divisions to Australia from the Middle East in 1942 coincided with the arrival of large numbers of American troops, including the US 32nd and 41st Infantry Divisions. From April 1942 MacArthur took over command of all US and Australian forces in the newly formed South West Pacific Area as Supreme Commander. Blamey had been appointed Commander-in-Chief AMF in March following his promotion to general, setting up Land Headquarters to subsume the role of the Military Board, which was suspended on 30 July. As Commander-in-Chief AMF he reported directly to MacArthur and was subsequently also given command of Allied Land Forces in the theatre. Yet although Australian forces made up the bulk of the Allied forces in SWPA until 1944 in practice for political reasons MacArthur ensured that Blamey only commanded Australian forces, while he also limited the number of Australian staff officers posted to General Headquarters, and they remained underrepresented for the remainder of the war.
https://en.wikipedia.org/wiki?curid=22738876
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Besides the Town Center skyscrapers, Southfield's modern towers include the 26-story American Center (1975) by the SmithGroup and One Towne Square (1992) by Rossetti with 21-stories. Other notable centers of commerce in the area are Dearborn, Troy, and Auburn Hills. Dearborn contains the world headquarters of the Ford Motor Company. Dearborn's 14-story luxury Adoba Hotel (1976) with its contemporary arced design by Charles Luckman is among the region's conference centers, with 772 rooms. Rossetti designed Dearborn's modern Ritz-Carlton Hotel (1988) along with the complementary Fairlane Plaza North and South (1990) as well as the Parklane Towers (1973). Troy has a large number of office buildings, many of which are situated along the corridor of Big Beaver Road. The tallest of these is the Top of Troy (1975) building, a 27-story triangular tower. Troy also contains what is generally considered to be the most upscale shopping center in the region, the Somerset Collection.
https://en.wikipedia.org/wiki?curid=8692117
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"Ramaria botrytis" is an edible species, and some rate it as choice. Its taste is "slight", or "fruity", and has been likened to sauerkraut, green peanuts (fresh harvested peanuts that have not been dehydrated), or pea pods. Older fruit bodies develop an acidic flavor. It is sold in food markets in Japan as "Nedzumi-take", and harvested from the wild in Korea and Nepal. The thick base and main branches require longer cooking than the smaller branchlets. In the Garfagnana region of central Italy, the mushroom is stewed, or pickled in oil. Fruit bodies can be preserved by slicing thinly and drying. One field guide rates the edibility as "questionable", warning of the possible danger of confusing specimens with the poisonous "Ramaria formosa". Other authors warn that some individuals may experience laxative effects from consuming the mushroom. Caution is advised when collecting fruit bodies near polluted areas, as the species is known to bioaccumulate toxic arsenic.
https://en.wikipedia.org/wiki?curid=24661039
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Some strains of group A streptococci (GAS) cause severe infection. Severe infections are usually invasive, meaning that the bacteria has entered parts of the body where bacteria are not usually found, such as the blood, lungs, deep muscle or fat tissue. Those at greatest risk include children with chickenpox; persons with suppressed immune systems; burn victims; elderly persons with cellulitis, diabetes, vascular disease, or cancer; and persons taking steroid treatments or chemotherapy. Intravenous drug users also are at high risk. GAS is an important cause of puerperal fever worldwide, causing serious infection and, if not promptly diagnosed and treated, death in newly delivered mothers. Severe GAS disease may also occur in healthy persons with no known risk factors.
https://en.wikipedia.org/wiki?curid=58638
780,302
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The SSSI has a wide variety of habitats, with bare mud, sand and shingle characterising the intertidal zone along the whole of the coast, although higher areas may have algae or eelgrass that are grazed by ducks and geese in winter. The salt marshes which form on sheltered coasts, in the lee of islands, or behind spits are described in the SSSI notification document as "among the best in Europe" due to their exceptionally diverse flora. Sand dunes occur at several places along the coast, but the best examples are at Holme Dunes, Holkham, Blakeney Point, and Scolt Head Island. The latter two sites are also important for geomorphology research purposes as structures consisting mainly of shingle ridges. Reed beds are fairly localised, but substantial areas occur at Titchwell Marsh, Brancaster and Cley Marshes. Grassland is represented by grazing pasture reclaimed from former salt marsh, with wetter areas at Cley and Salthouse marshes. Woodland is limited in the SSSI, although a belt of Corsican pine planted at Holkham has provided shelter for other trees and shrubs to become established.
https://en.wikipedia.org/wiki?curid=34525509
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In 2010 journal articles were published by Yohannes Haile-Selassie and others describing the discovery of around 90 fossil specimens in the time period 3.6 to 3.8 million years ago (mya), in the Afar area of Ethiopia, filling in the time gap between "A. anamensis" and "Australopithecus afarensis" and showing a number of features of both. This supported the idea (proposed for instance by Kimbel et al. in 2006) that "A. anamensis" and "A. afarensis" were in fact one evolving species (i.e. a chronospecies resulting from anagenesis), but in August 2019, scientists from the same Haile-Selassie team announced the discovery of a nearly intact skull for the first time, and dated to 3.8 mya, of "A. anamensis" in Ethiopia. This discovery also indicated that an earlier forehead bone fossil from 3.9 mya was "A. afarensis" and therefore the two species over-lapped and could not be a chronospecies (noting that this does not prevent A. afarensis being descended from "A. anamensis", but would be descended from only part of the "A. anamensis" population). The skull itself was found by Afar herder Ali Bereino in 2016. Other scientists (e.g. Alemseged, Kimbel, Ward, White) cautioned that one forehead bone fossil, which they viewed as not conclusively "A. afarensis", should not be taken as disproving the possibility of anagenesis yet.
https://en.wikipedia.org/wiki?curid=1661402
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Russia recovered after their loss to Ukraine in the previous round to beat Egypt 3-1 and so did England who beat Vietnam with the same result after the heavy loss to the Netherlands. Sergey Karjakin and Ian Nepomniachtchi both won for Russia with the White pieces on board one and board three, respectively, while Gawain Jones and Nigel Short scored full point on the lower boards. Especially remarkable was Gawain Jones' win over Nguyễn Ahn Khoi with a positional queen sacrifice on move 15 for two minor pieces and the attack (see diagram). United States beat Serbia 3-1 thanks to the early wins by Hikaru Nakamura and Wesley So. Georgia extended their winning run with a crushing win 3½-½ against Spain, where only José Carlos Ibarra Jerez was able to hold Tornike Sanikidze to a draw. The upsets of the day are Cuba, Hungary and France who all lost to lower-rated Canada, Latvia and Paraguay, respectively. Cuba's Leinier Domínguez won against Canada's Evgeny Bareev on board one but his teammates lost on all other boards. Latvia scored two wins against Hungary on the first two boards, where Alexei Shirov beat Richárd Rapport as White and Igor Kovalenko defeated Ferenc Berkes; Csaba Balogh's win against Vladimir Sveshnikov on board four was enough just for minimal loss for his team. France's Maxime Vachier-Lagrave scored his first win at the Olympiad after three draws but his team suffered a 2½-1½ loss from Paraguay as Sébastien Mazé and Romain Édouard both lost.
https://en.wikipedia.org/wiki?curid=51472590
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A complete electronic structure offers great predictive power for organic transformations and dynamics, especially in cases concerning aromatic molecules, extended π systems, bonds between metal ions and organic molecules, molecules containing nonstandard heteroatoms like selenium and boron, and the conformational dynamics of large molecules such as proteins wherein the many approximations in chemical formalisms make structure and reactivity prediction impossible. An example of how electronic structure determination is a useful tool for the physical organic chemist is the metal-catalyzed dearomatization of benzene. Chromium tricarbonyl is highly electrophilic due to the withdrawal of electron density from filled chromium d-orbitals into antibonding CO orbitals, and is able to covalently bond to the face of a benzene molecule through delocalized molecular orbitals. The CO ligands inductively draw electron density from benzene through the chromium atom, and dramatically activate benzene to nucleophilic attack. Nucleophiles are then able to react to make hexacyclodienes, which can be used in further transformations such as Diels Alder cycloadditons.
https://en.wikipedia.org/wiki?curid=11304514
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These tactics were dictated by the forces on hand. The more well-off Crusader troops, such as the knights, were individually superior in a melee to any cavalry in the area at the time, and were relatively immune to arrows due to their armour. Nonetheless, they tended to be ill-disciplined in the face of arrow volleys. The Seljuks attempted to use this on several occasions to draw small groups of cavalry away from the main body where they could be destroyed piecemeal by superior numbers. An example of a tactical retreat by lightly armoured Seljuk cavalry leading to a tactical advantage and a surrounded Crusader force was at the Battle of Azaz (1125). An alternative or supporting tactic to feigned retreats that was used by the Seljuks and others was harassing the Crusader line to disorganise it and leave it open to a cohesive cavalry charge. Crusader generals would have needed to be careful to maintain discipline in the face of losses from arrows and to keep heavy cavalry reserves to repel probing attacks. Note that this analysis is only drawn from examination mainly of some battles between 1097 and the mid 12th century, and so does not include the tactics of the entire Crusader period which only truly ended in 1302.
https://en.wikipedia.org/wiki?curid=17416992
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The underlying concept of an ecosystem can be traced back to 1864 in the published work of George Perkins Marsh ("Man and Nature"). Within an ecosystem, organisms are linked to the physical and biological components of their environment to which they are adapted. Ecosystems are complex adaptive systems where the interaction of life processes form self-organizing patterns across different scales of time and space. Ecosystems are broadly categorized as terrestrial, freshwater, atmospheric, or marine. Differences stem from the nature of the unique physical environments that shapes the biodiversity within each. A more recent addition to ecosystem ecology are technoecosystems, which are affected by or primarily the result of human activity.
https://en.wikipedia.org/wiki?curid=9630
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Pile continued studying the problem, and returned with a proposal to fire only 150 shells at a single rocket, with those shells using a new fuse that would greatly reduce the number that fell back to Earth unexploded. Some low-level analysis suggested that this would be successful against 1 in 50 rockets, provided that accurate trajectories were forwarded to the gunners in time. Work on this basic concept continued and developed into a plan to deploy a large number of guns in Hyde Park that were provided with pre-configured firing data for grids of the London area. After the trajectory was determined, the guns would aim and fire between 60 and 500 rounds.
https://en.wikipedia.org/wiki?curid=32786
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formula_2Selection of an instruction set architecture affects formula_3, whereas formula_4 is largely determined by the manufacturing technology. Classic Complex Instruction Set Computer (CISC) ISAs optimized formula_5 by providing a larger set of more complex CPU instructions. Generally speaking, however, complex instructions inflate the number of clock cycles per instruction formula_6 because they must be decoded into simpler "micro-operations" actually performed by the hardware. After converting X86 binary to the micro-operations used internally, the total number of operations is close to what is produced for a comparable RISC ISA. The iron law of processor performance makes this trade-off explicit and pushes for optimization of formula_7as a whole, not just a single component.
https://en.wikipedia.org/wiki?curid=59843147
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It concludes that Debye's actions in 1933–45 were based on the nineteenth-century positivist view of science which saw research in physics as generating blessings for humankind. The report states that, by his contemporaries, Debye was considered an opportunist by some and as a man of highest character by others. The report asserts that Debye was not coerced by the Nazis into writing the infamous DPG "Heil Hitler" letter and that he also did not follow the lead of other societies in doing so but, rather, other societies followed his lead. The NIOD report also concludes that Debye felt obliged to send the letter and that it was, for him, simply a confirmation of an existing situation. The report argues that Debye, in the Third Reich, developed a survival method of ambiguity which allowed him to pursue his scientific career despite the political turmoil. Crucial to this survival method was the need to keep ready an escape hatch, for example in his secret dealings with the Nazis in 1941, if needed.
https://en.wikipedia.org/wiki?curid=37067
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After his death, Australia's largest communicable diseases research institute—the Macfarlane Burnet Centre for Medical Research was renamed in his honour. The Burnet Clinical Research Unit of the Walter and Eliza Hall Institute was also named in his honour in 1986. In 1975 his work on immunology was recognised by a 33-cent stamp released by Australia Post. Seven Australian medical scientists were commemorated in the issue of a set of four Australian stamps released in 1995; he appears on the 45-cent stamp with fellow University of Melbourne graduate Jean Macnamara. He also appears on a Dominican stamp that was issued in 1997. The centenary of his birth was celebrated in Australia in 1999; a statue of him was erected in Franklin Street, Traralgon; and several events were held in his honour including the release of a new edition of by Oxford University Press.
https://en.wikipedia.org/wiki?curid=417493
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Liquid methane/LNG has several advantages over LH. Its performance (max. specific impulse) is lower than that of LH but higher than that of RP1 (kerosene) and solid propellants, and its higher density, similarly to other hydrocarbon fuels, provides higher thrust to volume ratios than LH, although its density is not as high as that of RP1. This makes it specially attractive for reusable launch systems because higher density allows for smaller motors, propellant tanks and associated systems. LNG also burns with less or no soot (less or no coking) than RP1, which eases reusability when compared with it, and LNG and RP1 burn cooler than LH so LNG and RP1 do not deform the interior structures of the engine as much. This means that engines that burn LNG can be reused more than those that burn RP1 or LH. Unlike engines that burn LH, both RP1 and LNG engines can be designed with a shared shaft with a single turbine and two turbopumps, one each for LOX and LNG/RP1. In space, LNG does not need heaters to keep it liquid, unlike RP1. LNG is less expensive, being readily available in large quantities. It can be stored for more prolonged periods of time, and is less explosive than LH.
https://en.wikipedia.org/wiki?curid=520402
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Researchers at UCLA used a brain-imaging tool to identify a certain protein found in five retired NFL players. The presence and accumulation of tau proteins found in the five living players, are associated with Alzheimer's disease. Previously, this type of exam could only be performed with an autopsy. Scientists at UCLA created a chemical marker that binds to the abnormal proteins and they are able to view this with Positron Emission Tomography (PET) scan. Researcher at UCLA, Gary Small explains, "Providing a non-invasive method for early detection is a critical first step in developing interventions to prevent symptom onset and progression in CTE".
https://en.wikipedia.org/wiki?curid=36082813
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Since it is not clear that methotrexate therapy reduces the incidence of central nervous system relapse in PT-DLBCL, a phase II non-comparative clinical study to determine the feasibility and toxicity of the R-CHOP regimen plus intrathecal liposomal cytarabine and systemic intermediate-dose methotrexate followed by loco-regional radiotherapy has just been completed. Results of this study, particularly as it relates to central nervous system involvement, are awaited. Other clinical studies seek to determine if ibrutinib (an inhibiter of B-cell receptor signaling that causes B-cell apoptosis, i.e. death) lenalidomide (mechanism of action is unclear), monoclonal antibodies (e.g. atezolizumab, durvalumab, or pembrolizumab) that inhibit the actions of PDLI), or drugs that inhibit the NF-κB or PI3K/AKT/mTOR signaling pathway (i.e. Copanlisib, ONC210, acalabrutinib, and TAK659 ), when added to the R-CHOP regimen, can prevent or treat central nervous system involvement in various forms of lymphoma and therefore might be useful in PT-DLBCL.
https://en.wikipedia.org/wiki?curid=63040871
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The university is placed in an Urban areas setting touching the boundaries of some green Rural areas. The eastern bank of the Ganges is only 2000 meters from the University and its serene background is only 50 km from Kolkata. It is close to Kalyani Ghoshpara railway station, 10 minutes walking distance to Administration Building from the station, and the other campuses are around it. During Second world war this land was under the control of the American army who maintained an Army depot here. Few roadways and other constructions are still there to prove that past history. The Campus spans over a huge area of 400 acres (largest State University of West Bengal based on area).
https://en.wikipedia.org/wiki?curid=11018035
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Micro-nutrient transfer is thought, for the most part, to occur by passive transport across cellular membranes, both during absorption, from soil by fungi, and transfer from fungi to host plants. This is not always the case though and although research on the topic is limited, there is evidence of active transport and allocation of micro-nutrients in certain conditions. The upregulation of cation transporters is observed in orchid "D. officinale" symbioses, suggesting fungi may assisted in the transfer of nutrients from fungi to plant. Cations, especially iron, are often bound tightly to organic and clay substrates keeping them out of reach of plants, fungi and bacteria, but compounds such as siderophores are often secreted into the soil by fungi and bacteria to aid in the acquisition of these cations. A siderophore is a small molecule which has extremely high affinity for Fe3+ and is commonly found being utilized by many bacteria and fungal species. These compounds are released into the soil surrounding the hyphal web and strip iron from mineral compounds in the soil, the siderophore can then be reabsorbed into the fungal hyphae where the iron can be dissociated from the spiderohore and used. Haselwandter investigated the presence of siderophores in orchid associated mycorrhizal fungi within the genus "Rhizoctonia" which utilize the siderophore basidiochrome as the major iron-chelating compound. Other vital nutrients may be transferred between mycorrhizal fungi and orchid plants via specialized methods, such as chelating molecules, but more research on this subject is needed.
https://en.wikipedia.org/wiki?curid=55484311
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Outbreaks of Legionnaires' disease receive significant media attention, but this disease usually occurs in single, isolated cases not associated with any recognized outbreak. When outbreaks do occur, they are usually in the summer and early autumn, though cases may occur at any time of year. Most infections occur in those who are middle-aged or older. National surveillance systems and research studies were established early, and in recent years, improved ascertainment and changes in clinical methods of diagnosis have contributed to an upsurge in reported cases in many countries. Environmental studies continue to identify novel sources of infection, leading to regular revisions of guidelines and regulations. About 8,000 to 18,000 cases of Legionnaires' disease occur each year in the United States, according to the Bureau of Communicable Disease Control.
https://en.wikipedia.org/wiki?curid=41678169
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The Lithgow F90 was officially adopted by the Australian Defence Force in 2015, it was then designated as the Enhanced F88 (EF88) Austeyr. Its nominal cyclic rate of fire is 740 rounds per minute. The EF88 is part of the LAND 125 Soldier Combat System project and is a significant upgrade to the F88SA2. It was developed and produced at the Australian Defence Industries factory in Lithgow Small Arms Factory, which is now owned by Thales Australia to fulfil current and near future requirements for the Australian Defence Force. It was first displayed to the public in the middle of 2012 and the initial production was scheduled for 2013, its final design and testing ended later on that year. Internally and externally the EF88 is still similar to the Steyr AUG, although it has received many distinctive upgrades and changes. Upgrades include the following:
https://en.wikipedia.org/wiki?curid=249896
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Laycock was a teleologist. He also held a fundamental belief in the "unity of nature", and saw nature as working through an unconsciously acting principle of organisation. Through his teleological approach, he argued that the origins of the nervous system were based on a natural force which he named the "Unconsciously Acting Principle for Intelligence." This force provided a plan for organism construction, regulated organisms based on survival instinct, and acted on the brain to provoke the phenomena of thought. Laycock saw nature as purposeful in creating this force, which ultimately results in a self-conscious mind, and an unconscious intelligence where reflexes were seeded. Because of his teleological approach to seeing nature through a lens of purpose, Laycock used observation as his principal method of scientific inquiry. He did not advocate for microscopic experimentation, which he saw as unnecessary in studying nature's biological forces. Rather, he preferred passive observation of purposeful phenomena in nature, from which theories could be inducted.
https://en.wikipedia.org/wiki?curid=13548310
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