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Over his lifetime, Gessner amassed a considerable collection of plants and seeds and made extensive notes and wood engravings. In the last decade of his life he began to compile his major botanical work, "Historia plantarum". although he died prior to its publication his materials were utilised by many subsequent authors for the next two hundred years, these included some 1,500 engravings of plants and their important flowers and seeds, most of which were original. The scale and scientific rigour of these were unusual for the time, and Gessner was a skilled artist, producing detailed drawings of specific plant parts that illustrated their characteristics, with extensive marginal notation discussing their growth form and habitation. Finally, the work was published in 1754.
https://en.wikipedia.org/wiki?curid=162270
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In many ways military science was born as a result of the experiences of the Great War. "Military implements" had changed armies beyond recognition with cavalry to virtually disappear in the next 20 years. The "supply of an army" would become a science of logistics in the wake of massive armies, operations and troops that could fire ammunition faster than it could be produced, for the first time using vehicles that used the combustion engine, a watershed of change. Military "organisation" would no longer be that of the linear warfare, but assault teams, and battalions that were becoming multi-skilled with introduction of machine gun and mortar, and for the first time forcing military commanders to think not only in terms of rank and file, but force structure.
https://en.wikipedia.org/wiki?curid=86586
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Prescription immediate release (Niacor) and extended release (Niaspan) niacin are contraindicated for people with either active or a history of liver disease because both, but especially Niaspan, have been associated with instances of serious, on occasion fatal, liver failure. Both products are contraindicated for people with existing peptic ulcer disease, or other bleeding problems because niacin lowers platelet count and interferes with blood clotting. Both products are also contraindicated for women who are pregnant or expecting to become pregnant because safety during pregnancy has not been evaluated in human trials. These products are contraindicated for women who are lactating because it is known that niacin is excreted into human milk, but the amount and potential for adverse effects in the nursing infant are not known. Women are advised to either not nurse their child or discontinue the drug. High-dose niacin has not been tested or approved for use in children under 16 years.
https://en.wikipedia.org/wiki?curid=37996
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Trials conducted using a conventional, powered C-47, first conducting ordinary deadstick landings, then being towed by another C-47, indicated that the scheme was feasible. Therefore, a C-47-DL was taken in hand for conversion into a glider, which was given the designation XCG-17. The aircraft, formerly a Northwest Airlines DC-3 that had been impressed into military service at the start of World War II, was modified by the removal of the aircraft's engines; the nacelles, containing the landing gear, remained in place, covered with aerodynamically profiled hemispherical domes for streamlining, containing fixed weight to compensate for the removal of the engines. Other equipment, no longer necessary with the conversion to an unpowered configuration, was also removed to save weight; items removed included the aircraft's wiring and bulkheads, along with the navigator's and radio operator's positions.
https://en.wikipedia.org/wiki?curid=14770103
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Although known for his modesty and quiet dignity, Wythe eventually gained a radical reputation for his opposition to the Stamp Act of 1765 and later attempts by the British government to regulate the overseas colony. Meanwhile, Wythe maintained close friendships with successive Governors Francis Fauquier and Norborne Berkeley, 4th Baron Botetourt. Wythe also earned a reputation for personal integrity, which years later led Rev. Lee Massey to call Wythe "the only honest lawyer I ever knew." Fauquier, Wythe and college professor William Small often socialized together—conversing about philosophy, natural history, languages, history and other matters. In 1762, Small suggested Wythe supervise the legal training of a star student, Thomas Jefferson, which had profound impact that went beyond their lives.
https://en.wikipedia.org/wiki?curid=261191
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Lutembacher is caused indirectly by heart damage or disorders. Lutembacher's syndrome is caused by either birth defects where the heart fails to close all holes in the walls between the atria or from an episode of rheumatic fever where damage is done to the heart valves such as the mitral valve and resultant in an opening of heart wall between atria. With Lutembacher's syndrome, a fetus or infant is usually seen to have a hole in their heart wall (interatrial) separating their right and left atria. Normally during fetal development, blood bypasses the lungs and is oxygenated from the placenta. Blood passes from the umbilical cord and flows into the left atrium through an opening called the foramen ovale; the foramen ovale is a hole between the two atria. Once a baby is born and the lungs begin to fill with air and the blood flow of the heart changes, a tissue flap (somewhat like a trap door) called the septum primum closes the foramen ovale or hole between the two atria and becomes part of the atrial wall. The failure of the hole between the two atria to close after birth leads to a disorder called ASD primum. The most common problems with an opening found in the heart with Lutembacher's syndrome is Ostium Secundum. Ostium Secundum is a hole that is found within the flap of tissue (septum primum) that will eventually close the hole between the two atria after birth. With either type of ASD, ASD will usually cause the blood flow from the right atrium to skip going to the right ventricle and instead flow to the left atrium. If mitral stenosis (the hardening of flap of tissue known as a valve which opens and closes between the left atrium and ventricle to control blood flow) is also present, blood will flow into the right atrium through the hole between the atria wall instead of flowing into the left ventricle and systemic circulation. Eventually this leads to other problems such as the right ventricle failing and a reduced blood flow to the left ventricle.
https://en.wikipedia.org/wiki?curid=12367111
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During its commercial product history, it was often commented internally that the Honeywell Information Systems (HIS) (later Honeywell-Bull) sales and marketing staff were more familiar with and comfortable making the business case for Honeywell’s other computer line, the DPS 6 running GCOS. The DPS-6 and GCOS was a well-regarded and reliable platform for inventory, accounting, word processing, and vertical market applications, such as banking, where it had a sizeable customer base. In contrast, the full potential of Multics’ flexibility for even mundane tasks was not easy to comprehend in that era and its features were generally outside the skill set of contemporary business analysts. The scope of this disconnect was concretized by an anecdote conveyed by Paul Stachour, CNO/CSC:
https://en.wikipedia.org/wiki?curid=18847
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Leading earlier in the prelims, Italy's Alessio Boggiatto finished outside the podium by six-tenths of a second (0.60) in 4:15.93. South Africa's Terence Parkin, a deaf mute since birth, swam on the outside in lane eight, but pulled off a fifth-place effort in an African record of 4:16.92. He was followed in sixth spot by Australia's newcomer Justin Norris (4:17.87), and in seventh by Romania's Cezar Bădiță (4:20.91), who had been overshadowed in his presence by a doping ban before the start of the Games. In May 2000, Badita failed a doping test for a steroid nandralone when he competed at the Mare Nostrum meet in Barcelona, Spain. Japan's Shinya Taniguchi closed out the field to eighth place with a time of 4:20.93.
https://en.wikipedia.org/wiki?curid=12446535
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Sensory input from the limbs may truncate or extend individual phase durations in a process akin to finite state control (in which "if-then” rules determine when state transitions occur). For example, if a limb that is swinging forward reaches the end of swing in less time than the current CPG-generated flexor phase duration, sensory input would cause the CPG timer to terminate swing and start the stance phase. Furthermore, as body velocity increases, the pattern formation layer would increase muscle activation nonlinearly to provide increased load-bearing and thrust forces. It has been posited that in well-predicted movements, CPG-generated phase durations and muscle forces closely match those required by the evolving biomechanical events, minimizing the sensory corrections required. The term ‘‘neuromechanical tuning’’ has been coined to describe this process
https://en.wikipedia.org/wiki?curid=2645238
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Athenion replaced all the magistrates with his own men. Choosing this moment to return to Athens, Apellicon was welcomed as an old comrade. Athenion sent him to Delos in command of a force with instructions to recapture the Athenian national treasury there and bring the money to Athens. It is peculiar that the force he was given is more of a mob than a detachment of soldiers, and that Apellicon evidences total ignorance of military matters. Landing on the shore at night they encamp without a palisade, fail to set a proper watch, and proceed to drink into the small hours. The commander of the Roman guard, Orobius, leads his soldiers into the camp, slaughters 600 men, takes another 400 captive, and hunts the escapees through the countryside, burning them up in their hiding places. Better at running than fighting, Apellicon manages to escape to Athens, where he disappears from politics, at least in the sources, until the brief notice of his death, apparently not of interest to Sulla until then.
https://en.wikipedia.org/wiki?curid=1666053
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The SNPO set an objective for NERVA of 99.7 percent reliability, meaning that the engine would fail to perform as designed no more than three times in every thousand starts. To achieve this, Aerojet and Westinghouse estimated that they would require 6 reactors, 28 engines and 6 reactor in-flight test (RIFT) flights. They planned for 42 tests, considerably less than the 60 tests that the SNPO had thought might be required. Unlike other aspects of NERVA, RIFT was solely a NASA responsibility. NASA delegated responsibility for RIFT to Wernher von Braun's Marshall Space Flight Center (MSFC) in Huntsville, Alabama. Von Braun created a Nuclear Vehicle Projects Office at MSFC, headed by Colonel Scott Fellows, a USAF officer who had worked on ANP.
https://en.wikipedia.org/wiki?curid=712716
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In 1963, Gertrude F. Rempfer designed the electron optics for an early ultrahigh-vacuum (UHV) PEEM. In 1965, G. Burroughs at the Night Vision Laboratory, Fort Belvoir, Virginia built the bakeable electrostatic lenses and metal-sealed valves for PEEM. During the 1960s, in the PEEM, as well as TEM, the specimens were grounded and could be transferred in the UHV environment to several positions for photocathode formation, processing and observation. These electron microscopes were used for only a brief period of time, but the components live on. The first commercially available PEEM was designed and tested by Engel during the 1960s for his thesis work under E. Ruska and developed it into a marketable product, called the "Metioskop KE3", by Balzers in 1971. The electron lenses and voltage divider of the PEEM were incorporated into one version of a PEEM for biological studies in Eugene, Oregon around 1970.
https://en.wikipedia.org/wiki?curid=803716
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Mobile Suit Gundam: The 08th MS Team Miller's Report is a compilation film released on August 1, 1998. The film largely focuses on Shiro Amada's court martial over his concern towards the enemy. The film mixes footage from the first eight episodes along with new footage. It also introduces the titular character, Alice Miller, an Earth Federation investigator assigned to gather additional evidence against Shiro. The ending theme is by Chihiro Yonekura. "Miller's Report" was not fully shown on TV in America, although the new scenes were all spliced into the eighth episode for the Toonami broadcast. "Miller's Report" was released on DVD in America separately from the main series, but is included as a fifth disc with all 12 episodes (4 discs) in the Collector's Edition Box Set. Bandai Visual released the film on Blu-ray in 2011. The film explains the plot connection between episodes eight and nine by showing Eledore's return from leave and the team's issuance of new orders.
https://en.wikipedia.org/wiki?curid=304784
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The signing of the Quebec Agreement on 19 August 1943 merged Tube Alloys with the Manhattan Project. Akers had already cabled London with instructions that Chadwick, Peierls, Oliphant and Simon should leave immediately for North America to join the British Mission to the Manhattan Project, and they arrived the day the agreement was signed. Simon and Peierls were attached to the Kellex Corporation, which was engaged in the K-25 Project, designing and building the American gaseous diffusion plant. While Kellex was located in the Woolworth Building, Peierls, Simon and Nicholas Kurti had their offices in the British supply mission on Wall Street. They were joined there by Tony Skyrme and Frank Kearton, who arrived in March 1944. Kurti returned to England in April 1944 and Kearton in September. Peierls moved on to the Los Alamos Laboratory in February 1944; Skyrme followed in July, and Fuchs in August.
https://en.wikipedia.org/wiki?curid=1024759
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In 1999 Lowman became the Executive Director of Marie Selby Botanical Gardens in Sarasota, Florida where she helped raise donations over 100 percent and increased membership by "friend-raising". The Selby Garden's lecture series "Tuesdays In The Tropics" was well attended by the community with topics such as "Does Money Grow on Trees? Challenges of Rain Forest Conservation". During her tenure, the Gardens' budget shifted into the black from previous years and the membership more than doubled. When the board shifted away from a botanical and conservation-oriented mission, Lowman accepted an offer at New College of Florida as Professor of Biology and Environmental Studies. The Center for Canopy Ecology relocated from Selby Gardens to New College following Lowman.
https://en.wikipedia.org/wiki?curid=5792354
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Another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. In many cases, simple maintenance culture is not sufficient. Growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. For example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. Others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. Mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium.
https://en.wikipedia.org/wiki?curid=307065
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In allowing just 5 goals in the 4 games, Marc Behrend was awarded the Tournament MOP for the second time. He became just the second player to be honored twice and the only one to win on both occasions (Lou Angotti is the only other multiple-time winner as of 2019). Wisconsin played 4 players on the All-Tournament Team with Behrend joined by Chris Chelios, Patrick Flatley and Paul Houck. Behrend finished second in the nation with a 2.23 GAA and was tops with a .921 winning percentage but neither mark was good enough to get him named to the All-American West Team. The only Bader All-American was Flatley who was also the only First Team All-WCHA player. though Chelios, Houck and Bruce Driver made the second team. Jeff Sauer became the first person to win a championship in his inaugural season as head coach with a new team and was later joined by Brad Berry in 2016. The Badgers finished the tournament with a +16 goal differential, tying the mark held jointly by 1950 Colorado College and 1953 Michigan.
https://en.wikipedia.org/wiki?curid=61507475
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They outlined the situation as having several aspects from the viewpoint of the Nisei: (1) Relation to First Generation, (2) Relation to American Society, (3) Vocational and Employment Guidance, (4) Standard of Social Conduct, and (5) Religious Life. These young people were having identity issues, although in 1925, they didn't call them that. They were worried about how to respect and carry on their culture, but also wanted to be full-fledged Americans in an environment that was racially prejudiced and had a real lack of job opportunities. Japanese Americans were excluded from owning land, but agriculture was a big part of the Japanese American experience in those days. It would turn out later when they were incarcerated due to World War II, many of the successful Issei and Nisei lost all of the businesses that they had built.
https://en.wikipedia.org/wiki?curid=35326487
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Langley attended Boston Latin School and graduated from English High School of Boston, after which he became an assistant in the Harvard College Observatory. He then moved to a job at the United States Naval Academy, ostensibly as a professor of mathematics. However, he was actually sent there to restore the Academy's small observatory. In 1867, he became the director of the Allegheny Observatory and a professor of astronomy at the University of Pittsburgh (then known as the Western University of Pennsylvania), a post he kept until 1891 even while he became the third Secretary of the Smithsonian Institution in 1887. Langley was the founder of the Smithsonian Astrophysical Observatory. In 1875, he was elected as a member to the American Philosophical Society. In 1888 Langley was elected a member of the American Antiquarian Society. In 1898, he received the Prix Jules Janssen, the highest award of the Société astronomique de France, the French astronomical society.
https://en.wikipedia.org/wiki?curid=93840
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Faradion Limited, is a subsidiary of India's Reliance Industries. Its cell design uses oxide cathodes with hard carbon anode and a liquid electrolyte. Their pouch cells have energy densities comparable to commercial Li-ion batteries (160 Wh/kg at cell-level) with good rate performance till 3C and cycle lives of 300 (100% depth of discharge) to over 1,000 cycles (80% depth of discharge). Its battery packs have demonstrated use for e-bike and e-scooter applications. They demonstrated transporting sodium-ion cells in the shorted state (at 0 V), eliminating risks from commercial transport of such cells. It is partnering with AMTE Power plc (formerly known as AGM Batteries Limited).
https://en.wikipedia.org/wiki?curid=30765254
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In August 1914, a flotilla of ten U-boats sailed from their base in Heligoland to attack Royal Navy warships in the North Sea in the first submarine war patrol in history. Their aim was to sink capital ships of the British Grand Fleet, and so reduce the Grand Fleet's numerical superiority over the German High Seas Fleet. Depending more on luck than strategy, the first sortie was not a success. Only one attack was carried out, when "U-15" fired a torpedo (which missed) at , while two of the ten U-boats were lost. The had better luck. On 22 September 1914 while patrolling the Broad Fourteens, a region of the southern North Sea, "U-9" found three obsolescent British armoured cruisers (, , and ), which were assigned to prevent German surface vessels from entering the eastern end of the English Channel. The "U-9" fired all six of its torpedoes, reloading while submerged, and sank the three cruisers in less than an hour.
https://en.wikipedia.org/wiki?curid=4551386
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The XM1060 40-mm grenade is a small-arms thermobaric device, which was delivered to US forces in April 2003. Since the 2003 Invasion of Iraq, the US Marine Corps has introduced a thermobaric "Novel Explosive" (SMAW-NE) round for the Mk 153 SMAW rocket launcher. One team of Marines reported that they had destroyed a large one-story masonry type building with one round from . The AGM-114N Hellfire II, uses a Metal Augmented Charge (MAC) warhead, which contains a thermobaric explosive fill that uses aluminum powder coated or mixed with PTFE layered between the charge casing and a PBXN-112 explosive mixture. When the PBXN-112 detonates, the aluminum mixture is dispersed and rapidly burns. The result is a sustained high pressure that is extremely effective against people and structures.
https://en.wikipedia.org/wiki?curid=31418
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Although antibodies show preferential avidity for specific epitopes, they may partially or weakly bind to sites on nonspecific proteins (also called reactive sites) that are similar to the cognate binding sites on the target antigen. A great amount of non-specific binding causes high background staining which will mask the detection of the target antigen. To reduce background staining in IHC, ICC and other immunostaining methods, samples are incubated with a buffer that blocks the reactive sites to which the primary or secondary antibodies may otherwise bind. Common blocking buffers include normal serum, non-fat dry milk, BSA, or gelatin. Commercial blocking buffers with proprietary formulations are available for greater efficiency. Methods to eliminate background staining include dilution of the primary or secondary antibodies, changing the time or temperature of incubation, and using a different detection system or different primary antibody. Quality control should as a minimum include a tissue known to express the antigen as a positive control and negative controls of tissue known not to express the antigen, as well as the test tissue probed in the same way with omission of the primary antibody (or better, absorption of the primary antibody).
https://en.wikipedia.org/wiki?curid=1021210
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On 2 December he returned to London and began finding takers for his specimens, with Thomas Bell and the Revd. William Buckland interested in the reptiles. Darwin's reputation was being made by the giant mammal fossils. Owen's first surprising revelation was that a hippopotamus-sized fossil skull 2 feet 4 inches (710 mm) long which Darwin had bought for about two shillings near Mercedes while on a "galloping" trip 120 miles (190 km) from Montevideo was of an extinct rodent-like creature resembling a giant capybara, which Owen named "Toxodon". Darwin wrote to his sister Caroline that "[the fossils] are turning out great treasures" and of the "Toxodon", "There is another head, as large as a Rhinoceros which as far as they can guess, must have been a gnawing animal. Conceive a Rat or a Hare of such a size – What famous Cats they ought to have had in those days!" The College of Surgeons distributed casts of the fossils to the major scientific institutions.
https://en.wikipedia.org/wiki?curid=1632764
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A disproportionately grown upper or lower jaw causes dentofacial deformities. Chewing becomes problematic, and may also cause pain due to straining of the jaw muscle and bone. Deformities range from micrognathia, which is when the mandible does not grow far forward enough (over bite), and when the mandible grows too much, causing an under bite; all of which are uncomfortable. Also, a total maxilla osteotomy is used to treat the "long face syndrome", known as the skeptical open bite, idiopathic long face, hyper divergent face, total maxillary alveolar hyperplasia, and vertical maxillary excess. Prior to surgery, surgeons should take x-rays of the patient's jaw to determine the deformity, and to make a plan of procedures. Mandible osteotomies, or corrective jaw surgeries, benefit individuals who have difficulty chewing, swallowing, TMJ pains, excessive wear of the teeth, open bites, overbites, underbites, or a receding chin. The deformities listed above can be perfected by an osteotomy surgery of either the maxilla or mandible (whichever the deformity calls for), which is performed by an oral surgeon who is specialized in the working with both the upper and lower jaws. Orthognathic surgery is also available as a very successful treatment (90–100%) for obstructive sleep apnea.
https://en.wikipedia.org/wiki?curid=2108181
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There were over 400 cases caused by cVDPV2 in the same period, in sixteen countries. In addition, 48 cases of cVDPV1 were detected in the Democratic Republic of the Congo, 18 cases in Mozambique, 13 in Madagascar, and 3 in Malawi, while one case due to cVDPV3 in an unvaccinated three-year-old was identified in Israel. Vaccine-derived viral strains were also detected in environmental samples from a number of additional countries without diagnosed cases. From February to May, traces of cVDPV2 were discovered in sewage in London, United Kingdom; no cases of polio have been reported in the UK. This led the United Kingdom to declare a "national incident". However, authorities have said that the risk to the general public is "extremely low". In the United States, the first case since 2013 was reported in Rockland County, New York. The CDC said genetic sequencing has tied the samples of polio from Rockland County to strains found in Israel and the United Kingdom.
https://en.wikipedia.org/wiki?curid=9901652
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After finishing his doctorate, Manabe went to the United States to work at the General Circulation Research Section of the U.S. Weather Bureau, now the Geophysical Fluid Dynamics Laboratory of NOAA, continuing until 1997. From 1997 to 2001, he worked at the Frontier Research System for Global Change in Japan serving as Director of the Global Warming Research Division. In 2002 he returned to the United States as a visiting research collaborator at the Program in Atmospheric and Oceanic Science, Princeton University. He currently serves as senior meteorologist at the university. He also engaged as a specially invited professor at Nagoya University from December 2007 to March 2014.
https://en.wikipedia.org/wiki?curid=7994952
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Evolutionary biology has been the subject of extensive mathematical theorizing. The traditional approach in this area, which includes complications from genetics, is population genetics. Most population geneticists consider the appearance of new alleles by mutation, the appearance of new genotypes by recombination, and changes in the frequencies of existing alleles and genotypes at a small number of gene loci. When infinitesimal effects at a large number of gene loci are considered, together with the assumption of linkage equilibrium or quasi-linkage equilibrium, one derives quantitative genetics. Ronald Fisher made fundamental advances in statistics, such as analysis of variance, via his work on quantitative genetics. Another important branch of population genetics that led to the extensive development of coalescent theory is phylogenetics. Phylogenetics is an area that deals with the reconstruction and analysis of phylogenetic (evolutionary) trees and networks based on inherited characteristics Traditional population genetic models deal with alleles and genotypes, and are frequently stochastic.
https://en.wikipedia.org/wiki?curid=662088
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Non-life actuaries followed in the footsteps of their life compatriots in the early 20th century. In the United States, the 1920 revision to workers' compensation rates took over two months of around-the-clock work by day and night teams of actuaries. In the 1930s and 1940s, rigorous mathematical foundations for stochastic processes were developed. Actuaries began to forecast losses using models of random events instead of deterministic methods. Computers further revolutionized the actuarial profession. From pencil-and-paper to punchcards to microcomputers, the modeling and forecasting ability of the actuary has grown exponentially.
https://en.wikipedia.org/wiki?curid=43405
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There are certain disorders in the brain that can prevent someone from having the ability to perceive relative pitch. These disorders can be congenital or developed. Amusia is a term used to describe someone who has difficulty differentiating pitch or identifying music. Congenital amusia is often referred to as being tone-deaf. Those with congenital amusia can process speech, differences in people's voices and hear environmental sounds, but most cannot identify patterns in music. They describe it as not being able to "hear" music, which sounds like somebody banging different pots and pans, rather than a rhythmic melody. The level of amusia can differ too. Some people can distinguish different songs and "hear" the music, while others have absolutely no understanding of music. Amusia can also be developed through traumatic brain injuries or lesions and tumours on the brain. Those who once could perceive relative pitch can lose this ability through an event like a head injury in a car crash. Sometimes this condition is reversible, but there is not a way to know if the person will be able to distinguish pitches again. This reason for this condition is not exactly known, but research and brain scans indicate that part of the cause may be located in the frontal cortex of the brain.
https://en.wikipedia.org/wiki?curid=30930484
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Following his senior season at Tennessee, Olsen represented Canada at the 1978 Commonwealth Games in Edmonton, Alberta. His gold performance solidified his stature as one of the world's best javelin throwers. Queen Elizabeth presented Olsen with his gold medal. Only the boycott of the 1980 Summer Olympics in Moscow, Russia, stopped Olsen from possibly winning an Olympic medal. As the number three-ranked javelin thrower in the world at that time, Olsen had a legitimate chance of winning an Olympic medal. Olsen would go on to compete at the 1982 Commonwealth Games in Brisbane, Australia, placing fourth. Only an injury to his right shoulder prevented him from competing at the 1984 Summer Olympics in Los Angeles, California. He officially retired from the sport he loved in August 1985.
https://en.wikipedia.org/wiki?curid=35808592
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Many young women in mid-19th century England had no access to the kind of formal secondary schooling which would have enabled them to go straight into the same university courses as the young men – the first principal herself had never been a pupil in a school. So Newnham's founders allowed the young women to work at and to a level which suited their attainments and abilities. Some of them, with an extra year's preparation, did indeed go on to degree-level work. And as girls' secondary schools were founded in the last quarter of the 19th century, staffed often by those who had been to the women's colleges of Cambridge, Oxford and London, the situation began to change. In 1890 the Newnham student Philippa Fawcett was ranked above the Senior Wrangler, i.e. top in the Mathematical Tripos. By the First World War the vast majority of Newnham students were going straight into degree-level courses.
https://en.wikipedia.org/wiki?curid=498109
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Studies have proven that herbicide resistant pollen from transgenic rapeseed could spread up to 3 km, while the average gene spread of transgenic crops is 2 km and even reach to maximum 21 kilometers. The high aggressiveness of these GM crops could cause certain disasters by competing with traditional crops for water, light, and nutrients. Crossbreeding of spreading pollens with the surrounding organisms has led to the introduction of the modified resistant genes. An international database that demonstrated genetic contaminations with undesired seeds has been a major problem due to the expansion of field trials and commercially viable cultivation of GM crops around the world. Even a decrease in the number of one pest under the impact of a pest-resistant weed could increase the population of other pests that compete with it. Beneficial insects, so named because they prey on crop pests, were also exposed to dangerous doses of Bt.
https://en.wikipedia.org/wiki?curid=216102
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In October 1868 the MIT architecture department opened with four students in the four-year course. Almost a thousand miles to the west, newly appointed Regent John Milton Gregory, at the newly established center of learning, the Illinois Industrial University (renamed the University of Illinois in 1878), also realized the need for formal professional training in architecture. Architecture was included in the Polytechnic Department of the proposed administrative structure Gregory presented to the trustees in May 1867. The first student in this curriculum, Nathan Clifford Ricker arrived in Urbana on January 2, 1870. Ricker became the first graduate of an architecture program in the United States in March 1873. He later became head of the Department of Architecture and oversaw the architectural education of many students. One, Mary Louisa Page, was the first woman to graduate with a degree in architecture in North America when she graduated from the University of Illinois in 1879.
https://en.wikipedia.org/wiki?curid=9283974
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The first commercially practical closed-circuit scuba was designed and built by the diving engineer Henry Fleuss in 1878, while working for Siebe Gorman in London. His self-contained breathing apparatus consisted of a rubber mask connected to a breathing bag, with (estimated) 50–60% O supplied from a copper tank and CO scrubbed by rope yarn soaked in a solution of caustic potash; the system giving a duration of about three hours. Fleuss tested his device in 1879 by spending an hour submerged in a water tank, then one week later by diving to a depth of 5.5 m in open water, upon which occasion he was slightly injured when his assistants abruptly pulled him to the surface.
https://en.wikipedia.org/wiki?curid=294126
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Thanks to the development of technology since the original proposal, new experimental data has been collected and additional mechanistic details of neuronal control have been developed. It has been determined that consciousness states can be described with three values, and the AIM model is a model that uses these values for representing the similarities and differences between waking and dreaming. It is a three-dimensional state-space model that describes different states of the brain and their variance throughout the day and night. It is composed of three different values: A – activation, I – input-output gating, and M – modulation. The model is limited however, in that it cannot yet explain the regional differences in brain activity that distinguish REM sleep from waking. Other limitations include the inability to quantifiably identify and measure M in humans. During waking and activation of primary and secondary consciousnesses, high values of A, I, and M have been observed, but during REM sleep high values of A but low I and M have been observed.
https://en.wikipedia.org/wiki?curid=30875305
1,300,973
1,478,107
On 26 March near Korostyshev, "Grandfather" was hit by artillery fire and was out of action for a short time. Most likely it was this same Garford that took part in the hunt for a Red Army Austin which broke into the area of Zhitomir and single-handedly fought against superior Polish forces. A second armoured vehicle was seized around this time and brought into service with the armoured platoon, receiving the name " Zagłoba" (in honour of a character from the novel "With Fire and Sword" by G. Sienkiewicz). A third Garford (a naval variant called "Uralets") was taken by the Poles in battle on the Bobruisk - Mogilev highway near the village of Stolopisch. Moreover, according to Polish records, during the infantry attack they managed to destroy a Red Army Fiat and a Lanchester armoured car as well as damage one other of unknown type. The Garford was captured after falling into a ravine from which the crew were unable to extract it on their own. The Poles recovered it and towed it to Bobruisk where it was repaired. Later the armoured car, which received the name "General Szeptycki", was included in the "Wielkopolski pluton samochodów pancernych" ("Wiekopolski Armoured Vehicle Platoon"). A short while later the "General Szeptycki" was sent to Warsaw where it was at the disposal of the 3rd Armoured Division, and in 1921 it ended up in Grodno. According to materiel inventories in 1925 all three machines were transferred to Krakow where they were put into the 5th Armoured Division. But by this time the armoured vehicles were thoroughly worn out and in 1927 the Garfords were taken out of service by the Polish Army and at the start of the 1930s were gradually dismantled.
https://en.wikipedia.org/wiki?curid=26354934
1,477,275
1,287,727
This brief description has focused on the theory of stochastic geometry, which allows a view of the structure of the subject. However, much of the life and interest of the subject, and indeed many of its original ideas, flow from a very wide range of applications, for example: astronomy, spatially distributed telecommunications, wireless network modeling and analysis, modeling of channel fading, forestry, the statistical theory of shape, material science, multivariate analysis, problems in image analysis and stereology. There are links to statistical mechanics, Markov chain Monte Carlo, and implementations of the theory in statistical computing (for example, spatstat in R). Most recently determinantal and permanental point processes (connected to random matrix theory) are beginning to play a role.
https://en.wikipedia.org/wiki?curid=22037813
1,287,026
1,092,136
The Illinois Institute of Technology developed the concept of oil shale volumetric heating using radio waves (radio frequency processing) during the late 1970s. This technology was further developed by Lawrence Livermore National Laboratory. Oil shale is heated by vertical electrode arrays. Deeper volumes could be processed at slower heating rates by installations spaced at tens of meters. The concept presumes a radio frequency at which the skin depth is many tens of meters, thereby overcoming the thermal diffusion times needed for conductive heating. Its drawbacks include intensive electrical demand and the possibility that groundwater or char would absorb undue amounts of the energy. Radio frequency processing in conjunction with critical fluids is being developed by Raytheon together with CF Technologies and tested by Schlumberger.
https://en.wikipedia.org/wiki?curid=12321977
1,091,576
1,734,442
The Wealden Beds are confined to the south and increase in thickness from 107 to 716 m, between Upwey and Swanage. By 140 Mya, the waters covering Dorset's landmass had subsided, leaving the area almost completely terrestrial save for the large rivers that dominated it. These rivers drained the upland areas to the north and west, and were responsible for depositing much of the succeeding sediment across southern Dorset. Comprising clays, silts, sands, and grits, they cover the floors of the valleys between Lulworth and Swanage. The sands and grits are also exposed in the cliffs there, and form ridges along the valleys. Traces of granite from Cornubia, the landmass that later became Cornwall, were also washed down. The Wealden Beds contain a great deal of plant matter and charcoal, indicating periodic fires in the region. At Mupe Bay, some of the sands have been bound together by oil and formed into sandstone boulders, suggesting that oil production had already begun when these sands were deposited.
https://en.wikipedia.org/wiki?curid=1121663
1,733,465
952,149
Australia played a small role in the Italian Campaign. The RAN returned to the Mediterranean between May and November 1943, when eight were transferred from the British Eastern Fleet to the Mediterranean Fleet to protect the invasion force during the Allied invasion of Sicily. The corvettes also escorted convoys in the western Mediterranean before returning to the Eastern Fleet. No. 239 Wing and four Australian Article XV squadrons also took part in the Sicilian Campaign, flying from bases in Tunisia, Malta, North Africa and Sicily. No. 239 Wing subsequently provided air support for the Allied invasion of Italy in September 1943, and moved to the mainland in the middle of that month. The two Australian fighter bomber squadrons provided close air support to the Allied armies and attacked German supply lines until the end of the war. No. 454 Squadron was also deployed to Italy from August 1944, and hundreds of Australians served in RAF units during the campaign.
https://en.wikipedia.org/wiki?curid=4578255
951,644
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There are many benefits of cardiorespiratory fitness. It can reduce the risk of heart disease, lung cancer, type 2 diabetes, stroke, and other diseases. Cardiorespiratory fitness helps improve lung and heart condition, and increases feelings of wellbeing. Additionally, there is mounting evidence that CRF is potentially a stronger predictor of mortality than other established risk factors such as smoking, hypertension, high cholesterol, and type 2 diabetes. Recently, a new study demonstrated the levels of CRF were associated with early deaths <65 years old among recent generations. Low CRF might be emerging to a new risk factor for early death among US Baby Boomers and Generation Xers. Significantly, CRF can be added to these traditional risk factors to improve risk prediction validity.
https://en.wikipedia.org/wiki?curid=3115848
424,389
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State collection was changing depending on the political situation of the country and the development of science in the Jagiellonian University. At the end of the eighteenth century in the garden, there were about three thousand plant species, especially useful. Collection of plants declined in the early nineteenth century, and it was only in the 1820s under the direction of Luigi Estreicher (1786–1852) that it was rebuilt. The garden gained particular fame in the 1860s, at the time of Ignatius Raphael Czerwiakowski (1808–1882) [7]. Stock declined in the late nineteenth century, and only Marian Raciborski (1863–1917), explorer of the Polish flora and Java began its restoration in the early twentieth century (founded a new rock garden, the department of genetics and plant variability). Its present appearance owes garden Szafer Władysław (1886–1970), one of the Polish botanists. Since 1991 he is the director Bogdan Zemanek, for which management was carried out repairs greenhouses, boilers, College Śniadeckiego and side buildings.
https://en.wikipedia.org/wiki?curid=12607771
1,960,718
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Candida glabrata is a species of haploid yeast of the genus "Candida", previously known as "Torulopsis glabrata". Despite the fact that no sexual life cycle has been documented for this species, "C. glabrata" strains of both mating types are commonly found. C". glabrata" is generally a commensal of human mucosal tissues, but in today's era of wider human immunodeficiency from various causes (for example, therapeutic immunomodulation, longer survival with various comorbidities such as diabetes, and HIV infection), "C. glabrata" is often the second or third most common cause of candidiasis as an opportunistic pathogen. Infections caused by "C. glabrata" can affect the urogenital tract or even cause systemic infections by entrance of the fungal cells in the bloodstream (Candidemia), especially prevalent in immunocompromised patients.
https://en.wikipedia.org/wiki?curid=4634382
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Most anoles are brownish or green, but there are extensive variations depending on the exact species. The majority can change their color depending on things like emotions (for example, aggression or stress), activity level, levels of light and as a social signal (for example, displaying dominance), but evidence showing that they do it in response to the color of the background (camouflage) is lacking. Whether they do it in response to temperature (thermoregulation) is less clear, with studies supporting it and contradicting it. The extent and variations of this color changing ability differ widely throughout the individual species. For example, the Carolina (or green) anole can change its color from a bright, leafy green to a dull brown color, while the brown anole can only change its shade, ranging from pale gray-brown to very dark brown. Even the distinct green-to-brown change in the Carolina anole can happen in only a few minutes. The colors are the result of their skin pigment cells, the chromatophores, of which they have three main types, but the change occurs only in the melanophores. When triggered by melanophore-stimulating hormone and other hormones, the melanosomes of the melanophores partially cover the other skin pigment cells, giving the anole a darker or browner color. In most cases stress results in a darker/browner color, but in the aquatic anole, a species that is dark brown with a barred pattern and light brown stripes on the sides of its body and head, stress results in paler brown upper parts and the stripes turn pale blue-green.
https://en.wikipedia.org/wiki?curid=322654
531,988
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The city of Sumy has been subjected to air and artillery shelling several times. There are not many specialized bomb shelters in Sumy, the vast majority of them have been since the Second World War. Experts do not advise hiding in the basements of high-rise buildings, because there is a risk of buildings falling. That is why the university opened bomb shelters for citizens, residents of the districts. Sumy residents, who live not far from the university campuses, come to the beginning of the curfew and spend the night in the university shelters. For example, on March 12, enemy planes dropped 5 bombs near SumDU, which damaged more than 100 university windows. However, the people in the shelter were not injured. The university has promptly eliminated the consequences of the bombing and continues to operate (as far as the security situation allows).
https://en.wikipedia.org/wiki?curid=26773832
1,246,643
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The disease has been especially prevalent in areas of Great Britain and south-west England. Infection is most common at 16-20 °C during wet periods to allow for easy entry through the stomata. Poor soil drainage can contribute to "Mycosphaerella brassicicola" proliferation through allowing for the high levels of moisture required for the ascospores to infect their host. Intensive agricultural operations further enhance the spread of disease by wind and water from the close proximity of host crops, as well as the potential for contact to occur between infected and healthy crop foliage.
https://en.wikipedia.org/wiki?curid=11069128
1,894,777
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Fearing English and Dutch penetration into Siberia, Russia closed the Mangazeya seaway in 1619. Pomor activity in Northern Asia declined and the bulk of exploration in the 17th century was carried out by Siberian Cossacks, sailing from one river mouth to another in their Arctic-worthy "kochs". In 1648 the most famous of these expeditions, led by Fedot Alekseev and Semyon Dezhnev, sailed east from the mouth of Kolyma to the Pacific and doubled the Chukchi Peninsula, thus proving that there was no land connection between Asia and North America. Eighty years after Dezhnev, in 1728, another Russian explorer, Danish-born Vitus Bering on "Sviatoy Gavriil" made a similar voyage in reverse, starting in Kamchatka and going north to the passage that now bears his name (Bering Strait). It was Bering who gave their current names to Diomede Islands, discovered and first described by Dezhnev.
https://en.wikipedia.org/wiki?curid=25437008
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the hybrid technology between inorganic and organic components. The refractive index of a nanocomposite can be estimated as formula_1, where formula_2, formula_3 and formula_4 stand for the refractive indices of the nanocomposite, nanoparticle and organic matrix, respectively. formula_5 and formula_6 represent the volume fractions of the nanoparticles and organic matrix, respectively. The nanoparticle load is also important in designing HRIP nanocomposites for optical applications, because excessive concentrations increase the optical loss and decrease the processability of the nanocomposites. The choice of nanoparticles is often influenced by their size and surface characteristics. In order to increase optical transparency and reduce Rayleigh scattering of the nanocomposite, the diameter of the nanoparticle should be below 25 nm. Direct mixing of nanoparticles with the polymer matrix often results in the undesirable aggregation of nanoparticles – this is avoided by modifying their surface. The most commonly used nanoparticles for HRIPs include TiO (anatase, n=2.45; rutile, n=2.70), ZrO (n=2.10), amorphous silicon (n=4.23), PbS (n=4.20) and ZnS (n=2.36). Polyimides have high refractive indexes and thus are often used as the matrix for high-n nanoparticles. The resulting nanocomposites exhibit a tunable refractive index ranging from 1.57 to 1.99.
https://en.wikipedia.org/wiki?curid=30747791
1,291,043
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Some of the organizational management concepts needed to create 20th-century mass production, such as scientific management, had been pioneered by other engineers (most of whom are not famous, but Frederick Winslow Taylor is one of the well-known ones), whose work would later be synthesized into fields such as industrial engineering, manufacturing engineering, operations research, and management consultancy. Although after leaving the Henry Ford Company which was rebranded as Cadillac and later was awarded the Dewar Trophy in 1908 for creating interchangeable mass-produced precision engine parts, Henry Ford downplayed the role of Taylorism in the development of mass production at his company. However, Ford management performed time studies and experiments to mechanize their factory processes, focusing on minimizing worker movements. The difference is that while Taylor focused mostly on efficiency of the worker, Ford also substituted for labor by using machines, thoughtfully arranged, wherever possible.
https://en.wikipedia.org/wiki?curid=63137
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A computer-assisted parallel program generation support(P-NCAS), is a PSE, creates a new way to reduce the programming hard task for the computer programming. This program can avoid or reduce the chance that huge computer software breaking down so this restrict uncertainty and major accidents in the society. Moreover, partial differential equations(PDEs) problems can be solved by parallel programs which are generated by P-NCAS supports. P-NCAS employs the Single Program Multi Data (SPMD) and uses a decomposition method for the parallelisation. These enable users of P-NCAS to input problems described by PDES, algorithm and discretisation scheme etc., and to view and edit all details through the visualisation and windows for edition. At last, parallel program will be outputted in C language by P-NCAS and also include documents which show everything has inputted in the beginning.
https://en.wikipedia.org/wiki?curid=2266487
1,833,545
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In 1966, Martin Rees pointed out that "an object moving relativistically in suitable directions may appear to a distant observer to have a transverse velocity much greater than the velocity of light". In 1969 and 1970 such sources were found as very distant astronomical radio sources, such as radio galaxies and quasars, and were called superluminal sources. The discovery was the result of a new technique called Very Long Baseline Interferometry, which allowed astronomers to set limits to the angular size of components and to determine positions to better than milli-arcseconds, and in particular to determine the change in positions on the sky, called proper motions, in a timespan of typically years. The apparent velocity is obtained by multiplying the observed proper motion by the distance, which could be up to 6 times the speed of light.
https://en.wikipedia.org/wiki?curid=405711
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This problem can be reduced through the employment of reserved words, so that for example "if", "then", and "else" always are parts of an if-statement and cannot be names of variables, but a surprisingly large number of useful words may thereby become unavailable. Another approach is "stropping", whereby reserved words are marked off, say by placing them between special characters such as full stops, or apostrophes as in some versions of Algol. This means that codice_1 and codice_2 are different tokens, the latter being an ordinary name, but supplying all those apostrophes soon becomes irksome. For many languages, spacing supplies sufficient information though this may be complex. Often it is not just a space (or tab, etc.) but a character other than a letter or digit that terminates a possible token's text. In the above example, the "expression" of the if-statement must be within brackets so that the "(" definitely ends the identification of "if" and similarly, ")" enables the identification of "then"; further, other parts of a compound if-statement must appear on new lines: "else" and "end if" (or "endif") and "else if". By contrast, with Algol and others the brackets are not needed and all the parts of an if-statement can be on one line. With Pascal, if a or b then "etc." is valid, but if "a" and "b" are expressions, then they must be enclosed in brackets.
https://en.wikipedia.org/wiki?curid=2012090
1,649,508
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The quality of Olmsted's landscape architecture was recognized by his contemporaries, who showered him with prestigious commissions. Daniel Burnham said of him, "He paints with lakes and wooded slopes; with lawns and banks and forest-covered hills; with mountainsides and ocean views..." His work, especially in Central Park, set a standard of excellence that continues to influence landscape architecture in the United States. He was an early and important activist in the conservation movement, including work at Niagara Falls; the Adirondack region of upstate New York; and the National Park system; and, though little known, played a major role in organizing and providing medical services to the Union Army in the Civil War.
https://en.wikipedia.org/wiki?curid=53321
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SAXS and USAXS belong to a family of X-ray scattering techniques that are used in the characterization of materials. In the case of biological macromolecules such as proteins, the advantage of SAXS over crystallography is that a crystalline sample is not needed. Furthermore, the properties of SAXS allow investigation of conformational diversity in these molecules. Nuclear magnetic resonance spectroscopy methods encounter problems with macromolecules of higher molecular mass (> 30–40 kDa). However, owing to the random orientation of dissolved or partially ordered molecules, the spatial averaging leads to a loss of information in SAXS compared to crystallography.
https://en.wikipedia.org/wiki?curid=12235089
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Damage done by "J. virginiana" includes outcompeting forage species in pastureland. The low branches and wide base occupy a significant portion of land area. The thick foliage blocks out most light, so few plants can live under the canopy. The needles that fall raise the pH of the soil, making it alkaline, which holds nutrients such as phosphorus, making it harder for plants to absorb them. However, studies have found that "Juniperus virginiana" forests that replace grasslands have a statistically insignificant decrease to a significant increase in levels of soil nitrogen. "J. virginiana" forests have higher overall nitrogen use efficiency (NUE), despite the common grassland species "Andropogon gerardi" having a far higher NUE during photosynthesis (PNUE). The forests store much greater amounts of carbon in both biomass and soil, with most of the additional carbon stored aboveground. There is no significant difference in soil microbial activity.
https://en.wikipedia.org/wiki?curid=446150
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Williams commenced lecturing at McGill University in 1960, and was selected to be the Chairman of the Department of Mining and Metallurgy in 1966. As Chairman, he was instrumental in expanding the department at a time when only six degree programs in Metallurgical Engineering were being offered in Canadian universities, among which McGill's department was the oldest. During his tenure, seven new faculty members were added to the department, with the new faculty primarily focusing its research on extractive (hydro and pyro), process and physical metallurgy. Ties between the department and Canadian industries were also strengthened during this time. Throughout his career, Williams conducted research on a variety of topics ranging from esoteric studies of grain shape to the practical aspects of abrasion resistant cast irons for mineral comminution. Williams held the position of Chairman until 1980, and retired from teaching in 1992. From 1972 to 1973, he was President of the Metallurgical Society of CIM.
https://en.wikipedia.org/wiki?curid=36831466
2,080,111
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On 6 December 2019, a Libyan National Army (LNA) MiG-23MLD was shot down by forces loyal to the Government of National Accord (GNA). In the ongoing Libyan Civil War both parties are pushing back to service stored airframes after repairs with foreign assistance. The jet, serial 26144, was restored using the wings of two different airframes and became flyable again in August 2019, after around 20 years of storage. The jet was hit over the Yarmouk frontline in southern Tripoli and crashed in Al Zawiya city and the pilot, Amer Jagem was detained after ejecting. A video emerged showing the aircraft diving for attack with soldiers on the ground firing a Strela-2M MANPADS in response. The LNA reported they lost a MiG-23 due to technical fault, denying it crashed due to enemy fire.
https://en.wikipedia.org/wiki?curid=220186
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In a highly anticipated game, the Carlisle Indians (7–0–0) met the Princeton Tigers (5–1–0) at the Polo Grounds in New York City on November 2 before a crowd of thousands. In an upset, Princeton scored three touchdowns and a point after in a pouring rain, to win 16–0. Yale recorded another shutout, beating Washington & Jefferson 11–0 to increase its record to 6–0–1, while Harvard got past Brown, 6–5, to stay unbeaten at 7–0–0. Army and Michigan stayed unscored upon; Army beat Colgate 6–0, to improve its record to 4–0–1, while the Wolverines travelled south to Nashville to face Vanderbilt, winning 8–0. Sewanee defeated the University of Virginia in Norfolk, 12–0, and Pennsylvania hosted Lafayette in Philadelphia, winning 15–0 and extending its record to 8–1–0.
https://en.wikipedia.org/wiki?curid=14681008
1,516,116
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There is a widely used method for computation of FLCs, introduced by Marciniak in 1967. It assumes an inclined band in the investigated plane sheet piece with smaller thickness which denotes an imperfection. With this model limit strains can be calculated numerically. The advantage of this method is that any material model can be used and limits can also be obtained for nonproportional forming. However there is one drawback. Calculated forming limits are sensitive to the imperfection value. With the assumption of a strain rate sensitive material model realistic forming limits may be obtained which lie above theoretical limit strains. Basically with this calculation method smooth forming limit curves are generated for materials for which only one experimental value exists. A good overview of state of the art about FLC calculation methods is given in the proceedings of a conference held in Zurich in 2006 and the Numisheet conference in 2008.
https://en.wikipedia.org/wiki?curid=22488730
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The land on which the dojo and shrine were built was first purchased by Morihei Ueshiba, the founder of aikido, in 1940. In 1943 he built the first part of the current Aiki Jinja and an "outdoor dojo" where he lived a life of ""Buno Ichinyo"" (the union of agriculture and Budō). This dojo was completed in 1945 and was originally called "The Aiki Shuren Dojo" (合気修練道場, lit. harmonising drill dojo). At first the dojo did not include "tatami" mats, and students received training directly upon the wooden floor. Eventually 24 mats were installed. The dojo was later moved to the present day location and expanded to 60 mats. When the founder formally established the Aikikai for the promotion of aikido in 1948, the dojo served as the world headquarters for the art and remained so until the opening of the new Aikikai Hombu Dojo in 1956.
https://en.wikipedia.org/wiki?curid=1134759
2,002,071
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The reflection of a laser pulse from the surface of an elastic solid can give rise to various types of elastic waves that propagate inside the solid or liquid. In other words, the light can excite and/or amplify motion of, and in, materials. This is the subject of study in the field of optomechanics. The weakest waves are generally those that are generated by the radiation pressure acting during the reflection of the light. Such light-pressure-induced elastic waves have for example observed inside an ultrahigh-reflectivity dielectric mirror. These waves are the most basic fingerprint of a light-solid matter interaction on the macroscopic scale. In the field of "cavity" optomechanics, light is trapped and resonantly enhanced in optical cavities, for example between mirrors. This serves the purpose of gravely enhancing the power of the light, and the radiation pressure it can exert on objects and materials. Optical control (that is, manipulation of the motion) of a plethora of objects has been realized: from kilometers long beams (such as in the LIGO interferometer) to clouds of atoms, and from micro-engineered trampolines to superfluids.
https://en.wikipedia.org/wiki?curid=43709
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While political debate over the wisdom of placing all satellite and launch technology on the US Munitions List (USML) has been ongoing since the advent of ITAR regulation in 1999, there has been a shift in political opinion since 2007. In late 2012, the US Congress passed the 2013 defense authorization bill which, if signed into law, will allow U.S. satellite manufacturers to "be more able to collaborate with international partners and [place] U.S. component makers on a more even footing in the global marketplace." The bill "allows the president to remove commercial satellites and components from the U.S. Munitions List (USML) and allows him to decide which satellite technologies are the most important to protect. The bill still restricts the export and transfer of technology to China, Cuba, Iran, North Korea, Sudan and Syria."
https://en.wikipedia.org/wiki?curid=612446
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The powerpack of Boxer consists of a MTU 8V199 TE20 diesel engine developing (originally) 720 hp and coupled to an Allison HD4070 fully automatic transmission with seven forward and three reverse gears. The powerpack can be replaced under field conditions in approximately 20 minutes. The MTU 8V199 TE20 engine is a militarised development of the Mercedes-Benz OM 500 truck engine, modified by MTU to produce increased power via changes to the turbocharger, fuel injection and cooling systems. To maintain mobility levels at increased weights, the 8V199 TE20 is now available developing either or , and when the drive module is fitted with the 600 kW version of this engine it is designated A3. Boxer is fitted with three fuel tanks containing a total of 562 litres, divided between a 280-litre front tank, 238-litre rear tank, and a 44-litre reserve tank.
https://en.wikipedia.org/wiki?curid=656230
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Given the backdrop of high and persistent unemployment during the Great Depression, Keynes argued that there was no guarantee that the goods that individuals produce would be met with adequate effective demand, and periods of high unemployment could be expected, especially when the economy was contracting in size. He saw the economy as unable to maintain itself at full employment automatically, and believed that it was necessary for the government to step in and put purchasing power into the hands of the working population through government spending. Thus, according to Keynesian theory, some individually rational microeconomic-level actions such as not investing savings in the goods and services produced by the economy, if taken collectively by a large proportion of individuals and firms, can lead to outcomes wherein the economy operates below its potential output and growth rate.
https://en.wikipedia.org/wiki?curid=17326
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In addition to bomb damage assessment, targeting and aerial photography for the Bomber Command and FEAF, the 91st conducted Electronic Intelligence (ELINT) and "ferret" missions in theater mapping radar emissions of air defense sites. It conducted the first ferret missions ever by the USAF. Overflights of Soviet-controlled Far East islands began in 1951. An example of this type of work was reconnaissance missions which were conducted over Karafuto following reports that the Soviets had built extensive underground installations and missile-launching facilities on the island. In Project 51, 91st SRW RB-45s took off from Yokotato conduct reconnaissance over the southern portions of Sakhalin Island. Photographic and radar reconnaissance overflight missions were also flown over the Murmansk-Kola Peninsula and Siberia. In late 1952, six RB-36s were sent to Yakota to fly with the 91st and fly high altitude reconnaissance over Manchurian targets.
https://en.wikipedia.org/wiki?curid=12557413
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On 15 January 1986, the launch of the stretched ATR 72 programme was announced. On 27 October 1988, the first prototype performed its maiden flight; one year later, on September 25, 1989, the ATR 72 received airworthiness certification from the French Directorate General for Civil Aviation. During the following month, on 27 October 1989, Finnish airline Finnair became the first airline to introduce the aircraft into service. Since the ATR 72 is assembled on the same production line as the smaller ATR 42, along with sharing the majority of subsystems, components, and manufacturing techniques, the two types support each other to remain in production. This factor may have been crucial as, by 2015, the ATR 42 was the only 50-seat regional aircraft that was still being manufactured.
https://en.wikipedia.org/wiki?curid=285018
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Between 2019 and 2021, a number of controversies revolving around the university's president Kyosuke Nagata came to light. Under Nagata's leadership the university became the first institution of higher education to receive large scale funding from the Ministry of Defense in December 2019. According to Alexandra Sakaki and Sebastian Maslow 'Illustrating a lack of consensus within the Japanese academic community...the university's official decision has triggered internal backlash and fierce criticism from academic and civic groups.' Indeed, the decision was heavily criticized by both the Science Council of Japan and Japanese academics. Critics were particularly dismayed by the fact that this marked a complete u-turn in university policy – only one year earlier in December 2018, the university had issued a policy statement against military research on campus.
https://en.wikipedia.org/wiki?curid=2080195
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Taking into account the definition of a crown group, crown eukaryotes could be seen as the aggrupation of all lineages descending from LECA (Last Eukarytotic Common Ancestor). This comprises a huge ensemble of taxa that seemingly diverged simultaneously and that conform the vast majority of the eukaryotic life, plants, fungi, animals and the variety of protist lineages. According to ribosomal RNA data, the radiation of eukaryotes from LECA would have originated from a series of basal lineages that branched off successively at this early stage. The hallmark of these organisms pertaining to crown eukaryotes is a higher complexity of their genetic and cellular machinery as compared with prokaryotes, enabled by their cellular compartmentalization. This complexity is accompanied by others extra cell-morphological features: endo/exocytosis, sexual reproduction, multicellularity, and vertical inheritance (as opposed to the horizontal gene transfer common among prokaryotes), that have led to the current morphological, behavioral and macroecological complexity of eukaryotes
https://en.wikipedia.org/wiki?curid=1694221
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Founded as the American Documentation Institute (ADI) in 1937, the group became the American Society for Information Science (ASIS) in 1968 to reflect the organization's interest in "all aspects of the information transfer process" such as, "designing, managing and using information systems and technology." Updating its name in 2000, the American Society for Information Science and Technology (ASIS&T) signaled the widespread prevalence and increasing centrality of online databases and similar technical aspects of the information profession. In 2013 the organization adopted its current name, while retaining the ASIS&T acronym, to better reflect its international membership and the increasingly global nature of our information society. Today the organization comprises professionals from various fields including engineering, linguistics, librarianship, education, chemistry, computer science, and medicine. Members share "a common interest in improving the ways society stores, retrieves, analyzes, manages, archives and disseminates information ".
https://en.wikipedia.org/wiki?curid=1464076
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According to ASHRAE, "Existing evidence for direct impacts of Carbon dioxide (CO) on health, well-being, learning outcomes, and work performance at commonly observed indoor concentrations is inconsistent, and therefore does not currently justify changes to ventilation and IAQ standards, regulations, or guidelines." NASA noted research on the CO levels found on submarines or spacecraft (of 3000ppm-7000ppm) had found it didn't affect the performance of astronaughts or submarine officers. However, they decided to limit it to 5000ppm to avoid headaches. Whereas in non-specialised populations, pure CO at a concentration common in indoor environments was found to affect high-level decision-making.
https://en.wikipedia.org/wiki?curid=219736
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In 2015 the technique was adapted to produce stacked, 3-D supercapacitors. Laser-induced graphene was produced on both sides of a polymer sheet. The sections were then stacked, separated by solid electrolytes, making multiple microsupercapacitors. The stacked configuration substantially increased the energy density of the result. In testing, the researchers charged and discharged the devices for thousands of cycles with almost no loss of capacitance. The resulting devices were mechanically flexible, surviving 8,000 bending cycles. This makes them potentially suitable for rolling in a cylindrical configuration.  Solid-state polymeric electrolyte-based devices exhibit areal capacitance of >9 mF/cm2 at a current density of 0.02 mA/cm2, over twice that of conventional aqueous electrolytes.
https://en.wikipedia.org/wiki?curid=42482555
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The gene encoding this enzyme has been recently identified. The sequence of amino acids of iodotyrosine deiodinase is highly conserved among mammals and contains three domains. Iodotyrosine deiodinase is a membrane protein, with the N-terminus functioning as a membrane anchor. It forms a dimer that is domain-swapped. Initially, iodotyrosine deiodinase was thought to contain only one flavin mononucleotide (FMN) in each dimer, but now iodotyrosine deiodinase is believed to have two FMN molecules for each homodimer. The enzyme has a characteristic α-β fold that all proteins from the NADH oxidase/flavin reductase superfamily have as well. Within the dimer interface, there are two equivalent active sites, each made from residues from both subunits. Thus, subunit association must be required for FMN binding and catalysis. Substrate binding causes a conformational change in the enzyme in order to close the active site, protecting the substrate and flavin from the solvent.
https://en.wikipedia.org/wiki?curid=21631002
1,623,367
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Endlicher described many new plant genera, including the genus "Sequoia", and also its only extant species "Sequoia sempervirens" (California coast redwood). Although Endlicher never offered an explanation for the name, later writers speculated that he must have been inspired by the achievements of the American Cherokee Indian linguist Sequoyah. John Davis credited Endlicher with naming the new species of Sierra redwood "Sequoyah gigantea" in 1847, the present day "Sequoiadendron giganteum" (California giant redwood), to honor Sequoyah's invention of the Cherokee syllabary. Recent scholarship supports this hypothesis; Endlicher appears to have combined the Latin "sequi" (meaning "to follow") with his admiration of Sequoyah and coined "Sequoia" because the number of seeds per cone in the newly classified genus fell in mathematical sequence with the other four genera in the suborder. .
https://en.wikipedia.org/wiki?curid=922788
1,642,156
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Christine A. Shoemaker joined the Department of Industrial Systems Engineering & Management and the Department of Civil and Environmental Engineering as NUS Distinguished Professor on 31 August 2015. Prof Shoemaker obtained her Ph.D. in Mathematics from the University of Southern California supervised by Richard Bellman in Dynamic Programming. Upon her graduation, she joined the School of Civil and Environmental Engineering and later the School of Operations Research and Information Engineering at Cornell University, Ithaca, NY, USA. She was promoted to full Professor in 1985. From 1985 to 1988, Professor Shoemaker was the Chair of the Department of Environmental Engineering at Cornell University. In 2002  Prof. Shoemaker was appointed the Joseph P. Ripley Professor of Engineering at Cornell University, USA. In 2015, Prof. Shoemaker became Distinguished Professor at National University of Singapore, in both Industrial Systems Engineering and Management Department and Civil and Environmental Engineering Department.  While in Singapore she has worked with Singapore water agency to apply her global optimization algorithms to improve the selection of parameters for computationally expensive partial differential equation models for lake hydrodynamics and complex multi-species water quality elements.These results used her group’s new parallel algorithms.
https://en.wikipedia.org/wiki?curid=52572607
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The Milstein Hall of Ocean Life is in the southeastern quadrant of the first floor, west of the Hall of Biodiversity. It focuses on marine biology, botany and marine conservation. The center of the hall contains a -long blue whale model. The upper level of the hall exhibits the vast array of ecosystems present in the ocean. Dioramas compare and contrast the life in these different settings including polar seas, kelp forests, mangroves, coral reefs and the bathypelagic. It attempts to show how vast and varied the oceans are while encouraging common themes throughout. The lower half of the hall consists of 15 large dioramas of larger marine organisms. It is on this level that the famous "Squid and the Whale" diorama sits, depicting a hypothetical fight between the two creatures. Other notable exhibits in this hall include the two-level Andros Coral Reef Diorama. Upper dioramas are smaller versions of the ecosystems when the bottom versions are much bigger and more life like.
https://en.wikipedia.org/wiki?curid=399990
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The sacrifice takes place near the end of the village festival. The animal is doused with water, and if it shivers, it is deemed to be possessed by the deity. Then, the animal is led to the shrine, and is restrained. One man takes an "aruval" or other sword and beheads the animal, which is then tossed aside to twitch and bleed out. For fowl, the head can be ripped off or the neck be broken without the use of a weapon. The head itself is placed in front of the deity with a foreleg in its mouth. It is believed that in this position the animal represents a demon, and by giving the demon to the deity it will be able to unite with her and become one again. Thus the villagers have done their duty. The meat is then taken and is used to make a "prasada", which is then offered to the deity. Afterwards, it is eaten by the devotees. It was usually the Dalits who got the meat from the buffalo sacrifice since only they would eat buffalo meat. At other times, however, anyone can walk up to the deity and make a sacrifice to them, potentially to ease some personal trouble such as a sick child or obtaining bad luck. The Muthumariamman temple in the Nilgiris was once the place where people swore solemn vows. This was sometimes used by the judicial system in the region during British times, and it was common for witnesses to make a vow of truth and make a sacrifice to Muthumariamman in the presence of a court official, so that all would know they spoke the truth.
https://en.wikipedia.org/wiki?curid=10203939
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The popularity of interference microscopy peaked around 1940–1970s and fell after that because of the complexity of the instrument and difficulties in both its use and in the interpretation of image data. In recent years, the classical interference microscope (in particular the Mach–Zehnder instrument) has been "rediscovered" by biologists because its main original disadvantage (difficult interpretation of translated interference bands or complex coloured images) can now be easily surmounted by means of digital camera image recording, followed by the application of computer algorithms that rapidly deliver the processed data as false-colour images of projected dry mass. Interference microscopy for industrial inspection, semiconductor inspection and surface structure analysis is highly developed and in widespread use.
https://en.wikipedia.org/wiki?curid=13082651
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Aldrin initially applied to join the astronaut corps when NASA's Astronaut Group 2 was selected in 1962. His application was rejected on the grounds that he was not a test pilot. Aldrin was aware of the requirement and asked for a waiver but the request was turned down. On May 15, 1963, NASA announced another round of selections, this time with the requirement that applicants had either test pilot experience or 1,000 hours of flying time in jet aircraft. Aldrin had over 2,500 hours of flying time, of which 2,200 was in jets. His selection as one of fourteen members of NASA's Astronaut Group 3 was announced on October 18, 1963. This made him the first astronaut with a doctoral degree which, combined with his expertise in orbital mechanics, earned him the nickname "Dr. Rendezvous" from his fellow astronauts. Although Aldrin was both the most educated and the rendezvous expert in the astronaut corps, he was aware that the nickname was not always intended as a compliment. Upon completion of initial training, each new astronaut was assigned a field of expertise; in Aldrin's case, it was mission planning, trajectory analysis, and flight plans.
https://en.wikipedia.org/wiki?curid=65777
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"Mariner 10" was a NASA probe whose primary objective was to observe the atmosphere, surface, and physical characteristics of Mercury and Venus. It was a low-cost mission completed for under $98 million. "Mariner 10" was launched at 12:45 am EST on November 3, 1973, from Cape Canaveral. Since Mercury is so close to the Sun it was too difficult to incorporate an orbit around Mercury in the route so "Mariner 10" orbited the Sun. In order to reach its destination, the satellite was accelerated with the gravity field of Venus. It then passed close to Mercury on March 29, 1974, as it flew towards the Sun. This was the first observation made of Mercury at close range. After the encounter "Mariner 10" was in an orbit around the Sun such that for every one of its orbits Mercury made two, and the spacecraft and the planet would be able to meet again. This allowed the probe to pass by Mercury two additional times before completing the mission; these encounters were made on September 21, 1974, and March 16, 1975. However, since the same side of Mercury was illuminated during each of the flybys, at the conclusion of the mission "Mariner 10" had only photographed 45% of its surface. The mission ended when the probe's attitude control gas ran out on March 24, 1975. As the spacecraft was no longer controllable without its nitrogen gas thrusters, a command was sent to the probe to shut down its transmitter.
https://en.wikipedia.org/wiki?curid=9125179
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Consisting of six 10 MW Ac projects, the first two were completed, by the POD Generating Group, in October, 2010, the Baseline Road Facility on the west side of the city, also known as SSM1, using 87,000 Q.BASE modules from Q-Cells. The project was acquired by Starwood Energy, in June, 2010. The remainder of the project was completed by Q-Cells. SSM2 is 30 MW Ac, and SSM3 is 10 MW Ac, both near Black Road on the east side of Sault Ste Marie. The total electricity peak demand for Sault Ste. Marie is 90-100 MW in summer and 140-150 MW in winter. The instantaneous demand is displayed on the SSM PUC website. The project was completed in 2011, with about 270,000 panels. Energy generated from each of the three stations will be sold to SSM PUC through 20 year Power Purchase Agreements using Ontario Power Authority's Renewable Energy Standard Offer Program.
https://en.wikipedia.org/wiki?curid=35280516
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A transmitter can be a separate piece of equipment, or an electronic circuit within another device. Most transmitters consist of an electronic oscillator which generates an oscillating carrier wave, a modulator which impresses an information bearing modulation signal on the carrier, and an amplifier which increases the power of the signal. To prevent interference between different users of the radio spectrum, transmitters are strictly regulated by national radio laws, and are restricted to certain frequencies and power levels, depending on use. The design must usually be type approved before sale. An important legal requirement is that the circuit does not radiate significant radio wave power outside its assigned frequency band, called "spurious emission".
https://en.wikipedia.org/wiki?curid=3548161
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In addition, the usage of natural gas in industry – both as a source of energy and as a raw material – is rapidly expanding, alongside the requisite infrastructure. This is giving companies a competitive advantage by reducing their energy costs and lowering national emissions. Since early 2013, almost the entire natural gas consumption of Israel has been supplied by the Tamar field, an Israeli–American private partnership. The estimated reserves amount to about 1 000 BCM, securing Israel's energy needs for many decades to come and making Israel a potentially major regional exporter of natural gas. In 2014, initial export agreements were signed with the Palestinian Authority, Jordan and Egypt; there are also plans to export natural gas to Turkey and the EU via Greece.
https://en.wikipedia.org/wiki?curid=397525
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Recent studies performed by Nilsson et al. examined the rates of bacterial genome reduction of obligate bacteria. Bacteria were cultured introducing frequent bottlenecks and growing cells in serial passage to reduce gene transfer so as to mimic conditions of endosymbiotic bacteria. The data predicted that bacteria exhibiting a one-day generation time lose as many as 1,000 kbp in as few as 50,000 years (a relatively short evolutionary time period). Furthermore, after deleting genes essential to the methyl-directed DNA mismatch repair (MMR) system, it was shown that bacterial genome size reduction increased in rate by as much as 50 times. These results indicate that genome size reduction can occur relatively rapidly, and loss of certain genes can speed up the process of bacterial genome compaction.
https://en.wikipedia.org/wiki?curid=35629150
1,115,800
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A matrix made up of many modules can separate to form multiple matrices with fewer modules, or they can combine, or recombine, to form a larger matrix. Some advantages of separating into multiple matrices include the ability to tackle multiple and simpler tasks at locations that are remote from each other simultaneously, transferring through barriers with openings that are too small for a single larger matrix to fit through but not too small for smaller matrix fragments or individual modules, and energy saving purposes by only utilizing enough modules to accomplish a given task. Some advantages of combining multiple matrices into a single matrix is ability to form larger structures such as an elongated bridge, more complex structures such as a robot with many arms or an arm with more degrees of freedom, and increasing strength. Increasing strength, in this sense, can be in the form of increasing the rigidity of a fixed or static structure, increasing the net or collective amount of force for raising, lowering, pushing, or pulling another object, or another part of the matrix, or any combination of these features.
https://en.wikipedia.org/wiki?curid=7649384
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While C enhances the efficiency of RuBisCO, the concentration of carbon is highly energy intensive. This means that C plants only have an advantage over C organisms in certain conditions: namely, high temperatures and low rainfall. C plants also need high levels of sunlight to thrive. Models suggest that, without wildfires removing shade-casting trees and shrubs, there would be no space for C plants. But, wildfires have occurred for 400 million years – why did C take so long to arise, and then appear independently so many times? The Carboniferous (~) had notoriously high oxygen levels – almost enough to allow spontaneous combustion – and very low , but there is no C isotopic signature to be found. And there doesn't seem to be a sudden trigger for the Miocene rise.
https://en.wikipedia.org/wiki?curid=11008314
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With "his horn-rimmed spectacles, broken tooth, beard, lank hair, string bag and apple", May stood out as a great eccentric on campus. Christine McNeil recalled: "'He never stays on topic,' wailed the note takers, as he soared off on a thousand tangents in his soft, sweet voice. 'Of course you all remember where Milton says...', he might begin, to our class of youthful ignoramuses. 'Read for 14 hours a day and marry young to get that side of things out of the way, he told us.'" His lectures were so popular that "students from all faculties would come to hear him lecture in mellifluous tones on Italian literature—and indeed on any subject that crossed his fertile mind".
https://en.wikipedia.org/wiki?curid=63335589
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In Ti-Al base alloys, the lamellar microstructure exhibits anisotropic properties in the lamellar direction and therefore the kinetics and orientation of its growth are integral to optimizing its mechanical properties. Selecting a directional solidification growth where the lamellar structure is parallel to the growth direction will result in a high strength and ductility. It is even more difficult to precipitate this phase since it is not formed from the liquid and instead from the solid state. The first way to overcome this challenge is by using a seed material, which is properly oriented and that nucleates new lamellae during processing with the same orientation as the original material. It is placed in front of the main bulk of material so that when the melt is solidifying it has a precedent for the correct orientation to follow. If a seed is not used, the other method of achieving the high strength single lamellar phase is to have the lamellar structure oriented along the growth direction. However, this is only successful for a small window of the solidification, as its success from the columnar growth of the beta phase followed by the equiaxed growth of the alpha phase and alloying with boron is compromised by the high thermal gradient of the cooling.
https://en.wikipedia.org/wiki?curid=12078110
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The school is home to a state-of-the-art solar energy system created by students at the school in June 2004. The 2 kW photovoltaic (PV) array, installed on the southeastern wall of the school, uses semiconductor technology to convert sunlight into pollution-free electricity. The solar equipment was donated by the MIT Space Systems Laboratory through a grant from NASA. The O'Bryant School also received support on curriculum development from the MIT Edgerton Center. Heliotronics of Hingham, MA provided a Solar Learning Lab, which gives students real-time system data on power production, efficiency, and weather conditions for analysis.
https://en.wikipedia.org/wiki?curid=7778206
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A student can join one of the six medical universities of Myanmar if he gets the highest scores in the science combination of the matriculation examination. This exam is highly competitive. Entrance is solely based on this examination and academic records have very minor consequences on an application. The undergraduate program is five years plus one year for work experience in government hospitals. After medical school, Myanmar medical graduates are under contract to spend one year of internship and three years of tenure in rural areas before they are eligible for most residency positions. The degree granted is Bachelor of Medicine and Bachelor of Surgery (MBBS). Further postgraduate qualifications may be obtained as a degree (MMedSc) and (DrMedSc).
https://en.wikipedia.org/wiki?curid=465584
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Similar to "Warhammer Fantasy Battle" players, "Lord of the Rings" players commonly collect and paint one army (or more) of their choice and find opponents (with similarly collected armies) to play against. Armies can be built up from through the purchase of boxed sets (usually having 10 or 12 plastic miniatures in each) or "blister packs" (usually containing no more than four finely detailed metal or resin miniatures) to build up a reasonable-sized fighting force. Others simply collect the miniatures because they like the way they look. One popular way of collecting was through "Battle Games in Middle-earth" — a De Agostini magazine that came with one or more free miniatures (some of which were initially exclusive to the publication) and contained detailed hobby guides.
https://en.wikipedia.org/wiki?curid=1739541
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In the early 20th century, the rediscovery of Mendel's work led to the rapid development of genetics by Thomas Hunt Morgan and his students, and by the 1930s the combination of population genetics and natural selection in the "neo-Darwinian synthesis". New disciplines developed rapidly, especially after Watson and Crick proposed the structure of DNA. Following the establishment of the Central Dogma and the cracking of the genetic code, biology was largely split between "organismal biology"—the fields that deal with whole organisms and groups of organisms—and the fields related to "cellular and molecular biology". By the late 20th century, new fields like genomics and proteomics were reversing this trend, with organismal biologists using molecular techniques, and molecular and cell biologists investigating the interplay between genes and the environment, as well as the genetics of natural populations of organisms.
https://en.wikipedia.org/wiki?curid=322460
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In a unique effort, growers, administrators, policy makers, and researchers are working on a solution for this immense "X. fastidiosa" threat. No cure has been found, but the understanding of "X. fastidiosa" and glassy-winged sharpshooter biology has markedly increased since 2000, when the California Department of Food and Agriculture, in collaboration with different universities, such as University of California, Davis; University of California, Berkeley; University of California, Riverside, and University of Houston–Downtown started to focus their research on this pest. The research explores the different aspects of the disease propagation from the vector to the host plant and within the host plant, to the impact of the disease on California's economy. All researchers working on Pierce's disease meet annually in San Diego in mid-December to discuss the progress in their field. All proceedings from this symposium can be found on the Pierce's disease website, developed and managed by the Public Intellectual Property Resource for Agriculture (PIPRA).
https://en.wikipedia.org/wiki?curid=5073625
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By 1909, Stravinsky had composed two more pieces, "Scherzo fantastique", Op. 3, and "Feu d'artifice" ("Fireworks"), Op. 4. In February of that year, both were performed in Saint Petersburg at a concert that marked a turning point in Stravinsky's career. In the audience was Sergei Diaghilev, a Russian impresario and owner of the Ballets Russes who was struck with Stravinsky's compositions. He wished to stage a mix of Russian opera and ballet for the 1910 season in Paris, among them a new ballet from fresh talent that was based on the Russian fairytale of the Firebird. After Anatoly Lyadov was given the task of composing the score, he informed Diaghilev that he needed about one year to complete it. Diaghilev then asked the 28-year-old Stravinsky, who had provided satisfactory orchestrations for him for the previous season at short notice and agreed to compose a full score. At about 50 minutes in length, "The Firebird" was revised by Stravinsky for concert performance in 1911, 1919, and 1945.
https://en.wikipedia.org/wiki?curid=38172
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Mazda claimed to have solved the apex seal problem, operating test engines at high speed for 300 hours without failure. After years of development, Mazda's first rotary engine car was the 1967 Cosmo 110S. The company followed with a number of Wankel ("rotary" in the company's terminology) vehicles, including a bus and a pickup truck. Customers often cited the cars' smoothness of operation. However, Mazda chose a method to comply with hydrocarbon emission standards that, while less expensive to produce, increased fuel consumption. Unfortunately for Mazda, this was introduced immediately prior to a sharp rise in fuel prices.
https://en.wikipedia.org/wiki?curid=33303
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All in-service Gripens as of January 2014 are powered by a Volvo RM12 turbofan engine (now GKN Aerospace Engine Systems), a licence-manufactured derivative of General Electric F404, fed by a Y-duct with splitter plates; changes include increased performance and improved reliability to meet single engine use safety criteria, as well as a greater resistance to bird strike incidents. Several subsystems and components were also redesigned to reduce maintenance demands. By November 2010, the Gripen had accumulated over 143,000 flight hours without a single engine-related failure or incident; Rune Hyrefeldt, head of Military Program management at Volvo Aero, stated: "I think this must be a hard record to beat for a single-engine application".
https://en.wikipedia.org/wiki?curid=87577
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Aside from creating and remodeling blood vessels, pericytes have been found to protect endothelial cells from death via apoptosis or cytotoxic elements. It has been shown "in vivo" that pericytes release a hormone known as pericytic aminopeptidase N/pAPN that may help to promote angiogenesis. When this hormone was mixed with cerebral endothelial cells as well as astrocytes, the pericytes grouped into structures that resembled capillaries. Furthermore, when the experimental group contained all of the following with the exception of pericytes, the endothelial cells would undergo apoptosis. It was thus concluded that pericytes must be present to ensure the proper function of endothelial cells, and astrocytes must be present to ensure that both remain in contact. If not, then proper angiogenesis cannot occur. It has also been found that pericytes contribute to the survival of endothelial cells, as they secrete the protein Bcl-w during cellular crosstalk. Bcl-w is an instrumental protein in the pathway that enforces VEGF-A expression and discourages apoptosis. Although there is some speculation as to why VEGF is directly responsible for preventing apoptosis, it is believed to be responsible for modulating apoptotic signal transduction pathways and inhibiting activation of apoptosis-inducing enzymes. Two biochemical mechanisms utilized by VEGF to accomplish this would be phosphorylation of extracellular regulatory kinase 1 (ERK-1, also known as MAPK3), which sustains cell survival over time, and inhibition of stress-activated protein kinase/c-jun-NH2 kinase, which also promotes apoptosis.
https://en.wikipedia.org/wiki?curid=1804463
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Several adverse biological events contribute to this secondary deterioration, including: release of excitatory amino acids which activate N-methyl-D-aspartate (NMDA) and amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors on neurons (30,37) and oligodendroglial precursors, accumulation of excitatory neurotransmitters, generation of reactive oxygen radicals, intracellular calcium accumulation and mitochondrial dysfunction. Whilst necrotic cell death is prominent in the immediate and acute phases of severe cerebral insults, the predominant mode of death during the delayed phase of injury appears to be apoptosis. Neuroprotective mechanisms need to interact with these mechanisms to have beneficial effect.
https://en.wikipedia.org/wiki?curid=24488474
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Serological and imaging tests are commonly used to diagnose this disease. Since the serological tests for alveolar echinococcosis only indicate exposure to the parasite and not ongoing infection, visualization of the parasitic mass is required to confirm the diagnosis. Frequently used serological tests include antibody tests, ELISA and indirect hemaglutination (IHA). An intradermal allergic reaction test (Casoni test) has also been used to diagnose patients. Imaging tests include: X-rays, CT scans, MRI, and ultrasound. Histology is another important diagnostic tool to use. In the past, the PAS staining technique has proven beneficial in helping determine if infections are caused by "Echinococcus multiocularis". More recently, a new immunohistochemistry technique that uses a monoclonal antibody (Em2G11) has provided professionals with more accuracy and precision in diagnosing "Echinococcus multiocularis" and distinguishing it from other species like "Echinococcus granulosus".
https://en.wikipedia.org/wiki?curid=1700949
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Hospitalized patients may need to receive solutions and medications that, if given through an ordinary intravenous therapy catheter, would severely damage both blood cells and the vascular system. In these cases, it is common to insert a central venous catheter. All such catheters placed for the purpose of venous access "and" being inserted in the upper body will ideally have the tip placed within the superior vena cava at or just above the cavoatrial junction. Passing the line "through" the junction and into the atrium is avoided by some practitioners, as they fear the result may be cardiac arrythmias and even cardiac tamponade, a potentially fatal outcome. However, other practitioners prefer the proximal RA and state that there is no evidence of harm. Modern catheter tip verification systems often rely on ECG readouts which correlate with tip position. A chest xray may still be obtained to confirm or when an ECG is contraindicated.
https://en.wikipedia.org/wiki?curid=20419472
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