text stringlengths 110 576k | id stringlengths 47 47 | dump stringclasses 1 value | url stringlengths 14 2.54k | date stringlengths 20 20 | file_path stringclasses 376 values | language stringclasses 1 value | language_score float64 0.65 1 | token_count int64 55 141k |
|---|---|---|---|---|---|---|---|---|
Adobe have announced a major update to Lightroom CC (cloud-based one).
New Lightroom CC now has Tone Curve and Split Toning.
Tone Curve and Split Toning (if you ever use it) are now available on Lightroom CC. Tone Curve is now available in the Lights panel, next to Auto button. You can choose between: Parametric Curve or Point Curve modes. You can also choose between Red, Green, and Blue channels.
There is also a new Auto Mode using Adobe’s Sensei technology.
In Adobe’s words:
Using an advanced neural network powered by Adobe Sensei, our artificial intelligence (AI) and machine learning platform, the new Auto Settings creates a better photo by analyzing your photo and comparing to tens of thousands of professionally edited photos to create a beautiful, pleasing image.
This new Auto Mode will also appear in Lightroom on the Web and Lightroom Classic CC, it’s not just in Lightroom CC.
In some other new features, you can now also:
- Change capture time of multiple images in Lightroom CC
- There are some refinements to Color Range Masking tool in Lightroom CC and Lightroom Classic CC
- New cameras are supported, like Sony Alpha 7R III, Google Pixel 2, and more
Adobe Creative Cloud subscribers get access to all these features immediately. | <urn:uuid:d1548972-7fa4-4963-b95f-ed7bfdb473f7> | CC-MAIN-2023-40 | http://www.photovideobeat.com/lightroom-cc-gets-a-major-update/ | 2023-09-26T05:31:29Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.853493 | 284 |
In May 1934, Col. James "Fitz" Fitzmaurice, former commanding officer of the Irish Free State Air Force signed an agreement for a new aircraft called the Bellanca 28-70 in which he intended to compete in the 1934 MacRobertson Race from England to Australia.
The MacRobertson Trophy Air Race (also known as the London to Melbourne Air Race) took place in October 1934 as part of the Melbourne Centenary celebrations. The race was devised by the Lord Mayor of Melbourne, Sir Harold Gengoult Smith and the prize money of £15,000 was provided by Sir Macpherson Robertson, a wealthy Australian confectionery manufacturer, on the condition that the race be named after his MacRobertson confectionery company and that it was organised to be as safe as possible.
Organised by the Royal Aero Club, the race ran from RAF Mildenhall in East Anglia to Flemington Racecourse, Melbourne, approximately 11,300 miles (18,200 km). There were five compulsory stops, at Baghdad, Allahabad, Singapore, Darwin and Charleville, Queensland; otherwise, the competitors could choose their own routes.
The basic rules were: no limit to the size of aircraft or power, no limit to crew size and that no pilot could join aircraft after it left England. Aircraft had to carry three days' rations per crew member, floats, smoke signals and efficient instruments. There were prizes for the outright fastest aircraft and for the best performance on a handicap formula by any aircraft finishing within 16 days. The initial field of over 60 had been whittled down to 20 starters.
Fitzmaurice's racer that he christened the Irish Swoop, did not exist but was going to be designed and built specifically for Fitzmaurice for the princely sum of $30,000 by Giuseppe Mario Bellanca.
Of conventional construction, Bellanca's design turned out to be an aircraft with typical Italian flair. The long-streamlined fuselage frame might have been of wood with fabric covering but the purposeful profile, topped by an extended canopy did not look like anything then built. Another unusual aspect was Bellanca's use of top and bottom braces for the low wing.
On 1 September 1934 with the start of the race now only slightly more than a month away, Fitzmaurice and his co-pilot, Eric "Jock" Bonar took the 'Irish Swoop' up for her first flight. The initial flight showed problems in aileron controls that necessitated a modification. Following a successful second test flight, the aircraft painted as "race 29" was crated and shipped by sea on the liner SS Bremen for offloading at Southampton.
However, this was not to be and she only went onto dry land at Bremerhaven in Germany. To add to their problems, the ferry flight was problematic, with a cracked cowling forcing a landing at Amsterdam. When she eventually arrived at the start, the MacRobertson race rules committee considered her not "race-ready". A more serious problem was then discovered; designed for a fuel capacity of 400 gallons, a total of 600 gallons of fuel were aboard the Bellanca and it thus exceeded its design specifications. The committee subsequently imposed a penalty that limited its fuel to 120 gallons. Fitzmaurice, unwilling to sacrifice his fuel load, withdrew the Irish Swoop hours before the race.
Recertified for its new configuration, Fitzmaurice and Bonar on 29 October 1934 set off from London to Baghdad, a distance of 4,100 km / 2546 miles, intending to set a new record. However, bad luck kept on following the 'Irish Swoop' when over Belgium, problems with a fairing and the cowling caused an end to the attempt.
The 28-70 was shipped back to the US to finish its tests, but was badly damaged in a landing accident on 15 April 1935 when a gust of wind flipped the aircraft on its back during a proving flight. She was rebuilt with a 900 hp P&W Twin Wasp and redesignated the 28-90. She was then purchased by British long-distance air racer Jim Mollison for $28,000, who used the her for a new transatlantic speed record.
PLEASE GO TO
and subscribe to our YouTube channel | <urn:uuid:3fc39c86-be79-4504-8ef5-f9cf8f2107ef> | CC-MAIN-2023-40 | http://www.pilotspost.com/arn0002550 | 2023-09-26T05:28:40Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.972215 | 922 |
Macbeth, thane of Glamis, heroically won the battle over an army of rebels, loyally comforting the power of King Duncan. But horrid ghosts always haunt the soul of men. In this case represented by three witches, who predict to our hero that he will become thane of Cawdor and king of Scotland. Macbeth is first surprised, and doubtful, but soon after, learning he just acquired the first title, he is stunned. No more is needed, he decides to become king, and proceeds to murder Duncan, in spite of the horror such an idea provokes in him. His last doubts are anyhow overridden by his wife, Lady Macbeth, who confronts his quandaries by challenging his manhood, his own worth. She despises her husband moral dilemma, which indicates a lack of courage. She calls on the powers of evil to help her accomplish what « must » be done. As a cunning heiress of Eve, she plots, telling her husband he must treacherously pretend to be a loyal host when poor Duncan blindly comes to the castle.
Macbeth, fearing his own nothingness, needs to prove himself, he needs to make his mark upon the world. To be someone, to be honored, to have power, at any cost. He has to crush in himself the admittance of anything that stands beyond his measly self. Truth, good or beauty, are internal necessities he pretends to ignore, in his mad personal quest. The whole play dramatizes the damaging physical and psychological effects of ambition on those who seek power for its own sake. As the plot unfolds, Macbeth is forced to commit more and more murders. In order to protect himself from enmity and suspicion, he becomes a tyrannical ruler. Wracked with guilt, engulfed in a streak of violence, he suffers from an increasingly acute form of delirious paranoia. For example, after killing his old friend Banquo, he watches his ghost barging in during a banquet. He responds with a senseless diatribe, shocking the assembly with his growing insanity. Inevitably, a bloodbath and consequent civil war swiftly throw Macbeth and his wife into the realms of madness and death. One can then conclude as Shakespeare that life is a tale told by an idiot, full of sound and fury, which signifies nothing. | <urn:uuid:a12e7e17-6d5f-4308-ab6c-e054ef53d7da> | CC-MAIN-2023-40 | http://www.pratiques-philosophiques.fr/en/being-someone/ | 2023-09-26T05:01:38Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.978135 | 488 |
Sunday, October 18, 2015
Who Should Dethrone John Cena as the United States Champion?
The number of different ways that WWE could go with writing Cena off of television are endless. I'm not even sure they're going to write him off of TV. I, much like everyone else, am speculating him to drop the US Title though. It needs to be under a great number of circumstances however. If the right person gets the belt, the prestige of it can continue to grow and someone could be pushed to that next level. If the wrong person gets the belt, it could flounder much like it did for years before Cena regained it.
So, who should that person be? I have a few ideas to present.
- Cesaro -
With that being said, it seems like I've written something like this a thousand times yet here we are again. Cena has been a vocal supporter of Cesaro for quite some time and is arguably the reason for his most recent push. Just this summer, Cesaro had two barnburners with Cena for the US Title despite being unable to get the job done. That will be the lead in to this match between the two. Cena issues the open challenge and Cesaro answers. They talk a minute about their previous contests and the bell rings. This time, he takes Cena to the limit once again and finishes the job to become the US Champion. Make this a grueling match that leaves both men exhausted to exemplify the story being told. Cena walks away while Cesaro takes the torch for a month or so. I hope to see this, but I'm not crossing my fingers.
- Dean Ambrose -
Ambrose is the lunatic who loves to fight so he could continue the US Title Open Challenge and it wouldn't seem weird or taint what Cena started. It would also set up for Cena's return in December and COULD also be a catalyst for an Ambrose heel turn. Cena comes back by answering Dean's Open Challenge and mentions how Ambrose stole his thunder by taking his open challenge schtick. Cena can push Dean's buttons by asking why he had to resort to copying him if he's such an anti-thesis to what Cena stands for. This leads to the match happening and Ambrose can resort to cheap tactics to return which can be the start of the aforementioned turn.
It's purely an idea, though. Ambrose is hot as a face so a turn may not be the best option although a US Title run certainly wouldn't hurt. Not to mention, the last match Cena & Ambrose had for the championship was quite entertaining!
- Kevin Owens -
Beyond that, the ultimatum of him being the person to unify the US & IC Titles will leave him as a critical part of WWE history books. It may be hard to properly build towards this program depending on how soon Cena will be taking leave, though. That's the only negative I can see when looking at this from the outside. It's definitely something to keep in mind whether it happens now or down the line. Owens undoubtedly has a moment similar to this in his future, it's just a matter of when.
- Samoa Joe -
Hell In A Cell is only a week away and Cena doesn't have an opponent for the show. I'm thinking he's going to simply issue his open challenge and my guess is that the person who answers it is who will dethrone him. Let that person be Samoa Joe. Imagine the atmosphere. Joe debuts on WWE PPV to go one on one with John Cena in a dream match that hasn't happened in a major company EVER. It's a throwback to both men's early training days in 1999-2000 and a true clash of superstars from two totally different worlds. A dream match that is 10 years in the making.
Joe is the husky, rough badass and Cena is the strong, clean cut hero. It's a similar dynamic to the Cena/Owens matches however I think Joe & Cena could produce something different. The thought of Joe unloading with one of his strike attacks on Cena with the crowd popping like crazy almost makes me jump out of my seat. I think these two could produce a barnburner that would see Joe ultimately assault Cena to the point of gaining the victory and winning the United States Championship. I'd have them go all out, honestly. It writes Cena off for a while due to the beating he took and how exhausting the match was, plus, it goes with his "never give up" character. Samoa Joe for US Champ? It's a viable choice from my point of view.
Who do you think will dethrone John Cena and become the new United States Champion in light of his upcoming sabbatical? Tweet me your thoughts @ThePWTruth on Twitter! Thanks for reading! | <urn:uuid:e3e8abdb-3d42-4876-a1c0-0d3125fc1d13> | CC-MAIN-2023-40 | http://www.prowrestlingtruth.com/2015/10/who-should-dethrone-john-cena-as-united.html | 2023-09-26T05:32:41Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.975779 | 985 |
After some playing around, I got it to work. I’m not really sure what I did. I suspect that I may have implemented Erwin’s suggestion incorrectly the first time. In any case, thanks for your help! And to answer your question, I quite like using the engine because once I program the stimuli, my students can take over and easily adapt the parameters of the experiment as they wish. Getting the stimuli in the first place has been the hard part! | <urn:uuid:cf6e41b0-bd8c-493c-8ddb-ee66eb7a0031> | CC-MAIN-2023-40 | http://www.qrtengine.com/forums/reply/2224/ | 2023-09-26T05:06:51Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.949994 | 109 |
I’ve lost count of how many times I’ve said that and as you can probably tell, essay writing is draining the life out of me. There’s an obvious negative correlation between the amount of admissions work I’m doing and the number of blog posts I write. I wonder if this will be the last post of the year?
I’m starting to look forward to when my life will get back to normal. No more heading straight from work to the library to write essays. Actually seeing the inside of a gym. I just to need to hunker down and bear through the pain for a few more weeks.
I feel my essays have gotten better over time. As you write you get new ideas and new feedback that just makes them better. I’m not sure how this bodes for the one I’ve already submitted, but hopefully this is good for my future apps.
As I get close to January, I’m going to make sure I have time to “plate.â€Â If any of you watch Iron Chef or Top Chef, like me, you’d know that the “plating†or arrangement of your food is almost as important as the taste. When it comes to MBA admissions, I consider plating the process of filling out the admissions form. Each application has a ton of free form fields that require the same level of attention as your essays. With my Haas app done already, I feel I’ll be good shape for doing this on my subsequent apps.
I’m approximately two weeks away from my first big deadline and overall, I feel I’m in good shape as it approaches. Though the emotional swings of confidence and weakness can be pretty rough. I have two three day weekends to work with and eight essays to write. Two of those are optional and two of those I already have a good start on. | <urn:uuid:a3fc15a5-dafa-48b2-96ea-81e696c349f1> | CC-MAIN-2023-40 | http://www.randomwok.com/admissions-2/my-essay-is-perfect-%E2%80%93-now-i-just-need-to-cut-out-200-words%E2%80%A6/ | 2023-09-26T06:36:38Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.953688 | 427 |
update 8pm: Exclusive with the Incumbent. Nuraina A. Samad, former political editor of NST, had lunch with Rafidah Aziz, it would seem from her posting Rafidah will defend her post.Rafidah Aziz, the incumbent president, told some friends over lunch today that "if that's what Shahrizat wants, I'll see her in the ring in March."
20/11 Wanita Umno deputy chief Shahrizat Abdul Jalil has announced she will be contesting the chief post/STAR
You can see this in any which way but, in essence, Shahrizat has broken an August 4 pact between the two, endorsed by the movement, for a peaceful and smooth hand over in June 2009.
Nuraina had predicted that Sharizat would take on Rafidah, here. Sakmongkol's analysis here is spot on, too.
Thursday, November 20, 2008
Rafidah vs Shahrizat, confirmed
This article has been edited for scoop.my Heading: Anwar Ibrahim’s much-awaited UN General Assembly debut Sub: Between his address to over...
03 Mar : The aerotrain at our main airport, KLIA, is quite old. Last century technology. But the trains have served us well. They have done ...
Amirudin is trying to silence (me) with the lawsuits - Razak Ismail, Green Party sec-gen Damansara, 30 July: I don’t quite understand why... | <urn:uuid:0327319b-9c20-4853-8d0e-5bcbddc2409e> | CC-MAIN-2023-40 | http://www.rockybru.com.my/2008/11/rafidah-vs-shahrizat-confirmed.html | 2023-09-26T04:55:32Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.967052 | 323 |
Jalan Kapas, 1feb23: It is hard to defend Anwar Ibrahim’s decision to appoint his own daughter, Nurul Izzah, as the Prime Minister’s senior financial advisor. The PM being Anwar himself, that is, aside from beiing the Minister of Finance as well. But Omar Ong, once an advisor to a prime minister of this country, and not one of Anwar’s favourite persons (if I’m not mistaken), suggests that Anwar’s appointment of his daughter could easily be justified. The good thing is Omar does not try to fool anyone by saying that the appointment isn’t an act of nepotism because it is, which ever way you want to see it. But so what? Omar argues in his latest posting on his blog Musings of the (occasional) thinker, planner and do-er that nepotism is alive and well in Malaysia, and has been so since Merdeka.
There are many who today argue that nepotism in whatever shape, form or circumstance, has no place at all in society and public office. That it is by definition a corrupt, self serving act that inevitably corrodes trust and good will in society. I am not one of them and if it is not already obvious, more sanguine in my view.
But I would very much like to hear how those who subscribe to such an unequivocal belief, would characterise the moral and ethical positions of Tun Abdul Razak and Tun Hussein Onn during their time in public office.
I am also certain there are those who honestly and sincerely believe nepotism has no place in society and I would like to understand your perspective as it applies present day to the 10th Prime Minister, his party as well as to the DAP, PAS and other Sarawak & Sabah based parties, where such practices are alive and well.
Is nepotism by sheer virtue of its presence, a death knell for public trust and good governance?
Or can it also be a benign force in a period of great personal mistrust, misunderstanding and Machiavellian machinations among the great, the good, the bad and downright ugly who lead in our name?
READ ALSO: Much Ado about Nurul, also by Omar Ong | <urn:uuid:40d09d21-f691-4896-8d8e-fc67886f202f> | CC-MAIN-2023-40 | http://www.rockybru.com.my/2023/02/nurul-izzahs-appointment-what-nepotism.html | 2023-09-26T04:52:54Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.976377 | 483 |
Stunning Art Show Focuses on Bayou, Water, Bees, and Plants
Sept. 25, 2016
Artists and the natural world is the theme of an inspiring show of photography, drawing, and painting in the lobby gallery of Williams Tower, 2800 Post Oak Blvd, through October 21.
Curator Sally Sprout has organized an exhibition of the work of four artists living in Houston who are “profoundly influenced by the relationship between human beings and the natural world.”
It is worth noting that for her paintings Janice Freeman appropriates the photographs of Buffalo Bayou taken by her husband, Geoff Winningham, for his landmark book, Along Forgotten River.
Below are some images from the show, which is free and open to the public and titled “Kaleidoscope: Approaching Nature.” | <urn:uuid:483bdfa1-e5ea-4b89-aee2-c2ec156bb900> | CC-MAIN-2023-40 | http://www.savebuffalobayou.org/?p=3138 | 2023-09-26T05:52:44Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.964689 | 172 |
What do you think of this nice plump fit rainbow trout ?, out on the new Togiak float tubing and taken in centre lake not in the margins as what would be considered normal locations and it mullered a big pink fluffy lure and just roared off with me in my tube in tow.
Took nearly 15 minutes to get it into the net as I only had a small point on and just had to wait until it rolled over. At the sink ready to fillet, cure and smoke ready for vac packing for future trout salads. Fly fishing is such a great sport at Lechlade fisheries and with two lakes to fish you should not go home fishless.
With many trips on board my trusty floating armchair I had the opportunity to purchase what is considered the roller of float tubes the Togiak and what a difference in speed and getting about the sleeker lines of this float tube has.
With the turned up bow there is less drag in the water so less effort needed by my short stumpy legs to power it along especially when it’s windy. Here is the tube after the first outing and it was well and truly christened with this fine catch. 4lb brownee too !!
You’ve see me dry now see what I look like wet bobbing about on the lake. You will be amazed how quick you can get about with the large flippers on, you also need them when you get into a fish too as you soon end up going round in circles. A strong fighting brownee can actually tow you along too.
I will fish like this all the time now apart from lakes or resevoirs that don’t allow them of course. Casting from the tubes takes a little time to get used to as your so low to the water and can easily dunk the fly everytime you get it wrong on the back cast.
Fishing the banks of a good large lake gives plenty of exercise by the time you’ve fished all the marks on the lake, but if you want to get all round the lake and across it then try one of these, they’re the dogs dangly bits.
Ok looks like your into some kinky type of fetish in all this kit but when you get out on the lakes and enjoy the freedom to fish anywhere without being restricted by high banks or hanging trees you will live to learn with the barracking.
Don’t know why I’m loitering infront of the ladies, bit worrying that ! but hey look at this bad boy well girl actually a 6lb female caught on a green daddy out in the tube on a large lake near Lechlade UK.
Shame really it did’t give much of an account of herself not what you would call a Fiesty Female by any means but it’s another one for the blog to shout about. Infact that day I had bought a six fish ticket and caught my quota all from 3-6 lb so good day that one and it was around November time 2010 so the lakes where getting chilly on the legs for tubing.
Good exerise though on a cold day you have to keep paddling just to keep warm
To say we got hooked onto fly fishing is an understatement and my son in law Chad decided to have a go and we showed him the basics from what little we new and off we went to the lakes. Fortunately his Uncle Tony is one of the balifs at the lakes we where using then and also a very good fly fisherman.
That day we arranged to meet him at the lakes so we all could learn from his experience. Chad was soon into fish and experiencing the buzz we had with those first few and still do.
Here he is with a brace of fine rainbow trout, not sure what he got them on as he fished with the balif all day and wasn’t giving up any info, good eh we bring him into the sport, show him what to do well a little bit and he catches the fish.
After 3 or 4 outings on the lakes and a load of flack from my son about Who’s the daddy then ! I managed to catch my first trout on the fly and it really gave me a buzz. Until you feel that first take and see your fly line shoot out infront of you it’s hard to describe.
Not a biggy by any standards but it sure did give a good account of itself, or perhaps I milked it for all it’s worth in case I didn’t catch another one that day. Fortunately I had two more that day and nearly actually managed to fill my 4 fish ticket on that lake.
I can even tell you now what I caught them on, a green and black montana for the first two and a small green daddy for the third one, Now Who’s The Daddy !!
With the amount of boat fishing trips we lose each year through bad weather and with the fact that myself and Andy my son have both taken days off from our business’s then we had to find something to satisfy our lust for catching fish.
Andy came up with the perfect birthday present a few years back and that was a days Fly Fishing instruction with a pro. Since that day we where both Hooked excuse the pun and when we get a blow out as we call it then fly fishing is on the cards.
We live in the Cotswolds so there are plenty of lakes all stocked with good size rainbow and brown trout and from our first time out we caught fish and that was it as they are such good sport. Fishing from the banks took some getting used to but when I saw a guy out fishing in a float tube we both decide to get one each and haven’t looked back since !!
That very first trout caught by Andy a few days after our tuition, that first one will always feel good. | <urn:uuid:6c8e49ec-0013-4b07-8a7d-43fa556d7028> | CC-MAIN-2023-40 | http://www.seafishingtackle4u.com/tag/fly-fishing/ | 2023-09-26T05:05:13Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.972475 | 1,218 |
Summer 2019 - STAT 203 E100
Introduction to Statistics for the Social Sciences (3)
Class Number: 2628
Delivery Method: In Person
Course Times + Location:
Tu 4:30 PM – 5:20 PM
AQ 3005, Burnaby
Th 4:30 PM – 6:20 PM
AQ 3005, Burnaby
Exam Times + Location:
Aug 8, 2019
7:00 PM – 10:00 PM
EDB 7618, Burnaby
Prerequisites:Recommended: 30 units including a research methods course such as SA 255, CRIM 220, POL 200, or equivalent.
Descriptive and inferential statistics aimed at students in the social sciences. Scales of measurement. Descriptive statistics. Measures of association. Hypothesis tests and confidence intervals. Students in Sociology and Anthropology are expected to take SA 255 before this course. Intended to be particularly accessible to students who are not specializing in Statistics. Students cannot obtain credit for STAT 203 if they already have credit for - or are taking concurrently - STAT 101, 201, 205, 285, or any upper division STAT course. Quantitative.
This course covers Chapters 1-9, 11, 12, 15-22, and 24-27 of the textbook. Chapters 7, 11, 19, and 24 are section reviews (and thus are optional). Details of the other chapters are as follows:
- Descriptive Statistics (Chapters 1, 2, and 4 of text) Basic graphical statistics (e.g. bar graphs, pie charts, histograms, time plots, scatterplots) and basic numerical statistics (e.g. mean, median, mode, quartiles, standard deviation, correlation) are discussed. Scales of measurement are distinguished (e.g. nominal, ordinal, ratio and interval).
- Probability (Chapters 3 and 12 of text) The normal distribution is introduced along with probability rules.
- Sampling (Chapter 8 of text) Various sampling designs such as simple random sampling are discussed. The implementation of sampling procedures is also presented.
- Experiments and Observational Studies (Chapters 8 and 9 of text) The design of experiments is introduced with an emphasis on randomization, treatments, subjects, factors, pairing and controls. Comparisons are made with observational studies.
- Inference (Chapters 15, 16, 17, 18) Concepts related to the construction of confidence intervals (e.g. sampling distributions, confidence level, width, interpretation, the effect of sample size) are discussed. Also basic concepts related to the testing of hypotheses (e.g. hypotheses, p-values, statistical significance) are presented.
- Estimation and Testing for One Sample Problems (Chapters 20 and 22 of text) Procedures for means and proportions are discussed with an emphasis on the use of statistical software and the interpretation of results.
- Estimation and Testing for Two Sample Problems (Chapters 21 and 23 of text) Procedures for means and proportions are discussed with an emphasis on the use of statistical software and the interpretation of results.
- One Way ANOVA (Chapter 27 of text) One way analysis of variance procedures are discussed with an emphasis on implementation using statistical software and the interpretation of results.
- Chi-Square Tests (Chapters 6 and 25 of text) Procedures for testing in contingency tables are discussed with an emphasis on the use of statistical software and the interpretation of results. Measures of association are discussed.
- Regression (Chapter 5 and 26 of text) Simple linear regression is introduced with an emphasis on carrying out regression on actual data using statistical software and the interpretation of results. Related concepts including residuals, least squares fit, testing and the construction of confidence intervals is addressed.
- Assignment 10%
- Webwork Quizzes 5%
- Midterm 1 15%
- Midterm 2 20%
- Final Exam 50%
MATERIALS + SUPPLIES:
R can be accessed via Jupyter, an online platform, at https://sfu.syzygy.ca/. Alternatively, R Studio and R statistical software can be downloaded free of charge from https://www.rstudio.com/ and https://cran.r-project.org/, respectively.
The Basic Practice of Statistics (8th ed.) & Sapling Plus (Sapling Plus is recommended, but not required) by D. S. Moore, W. I. Notz, and M. A. Fligner. Publisher: W.H. Freeman Publishers
Loose-leaf ISBN: 9781319188658 (available at SFU Bookstore)
Other options are available through the MacMillan Learning website.
Department Undergraduate Notes:
Students with Disabilites:
Students requiring accommodations as a result of disability must contact the Centre for Accessible Learning 778-782-3112 or firstname.lastname@example.org
Students looking for a Tutor should visit http://www.stat.sfu.ca/teaching/need-a-tutor-.html. We accept no responsibility for the consequences of any actions taken related to tutors.
SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the University community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS | <urn:uuid:0611c04f-b14b-4b85-bebe-45b2a65e29b9> | CC-MAIN-2023-40 | http://www.sfu.ca/outlines.html?2019/summer/stat/203/e100 | 2023-09-26T05:17:01Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.861036 | 1,294 |
My mate hade a Commodore and he snapped it in half. (they must all be shit)
I hear the ford is good for downhill and a bit of sliding but its a bitch to get back up the hill.
Both work well at Bathurst though.
I dont have a licence and cant drive but i realy think you should get a Ferrari or lambo. All the fast guys are using them so they must be the best.
Have you thought of looking in the trading post as lots of cheep second hand ones there.
Get a audi they r best for skids
i actually own a forrester! its not a newer one its a 99 but it does the job, epic skate wagon.
i'll swap you my forrester for your one? will throw in some stickers...
We have a forester and it's totally awesome. But it's a later model. 2010
We also have a falcon ute. 2002 model. If you want a bit older car I'd stick to a ford the parts are cheap and if you have a good mechanic it will go for ever with few costs. But the falcon can be quite thirst on fuel. If your able to shell out for a newer model. Say 2010 or newer I'd go the outback or a forester cheaper on fuel, better handelling on windy hills.
I know that's where you will want to drive it.
my skatewagon died this week RIP coony commodore [IMG]http://i1064.photobucket.com/albums/u378/keenbouthunting/YourPhoto_...[/IMG]
Get a Datto 120Y!
Depending on how much do you have to spend.
Circa $3000 - $6000
1992 - 1998 V6 VP-VS Commodore wagon - drive well, 9-10 L/100 on a run, roomy for sleeping, cheap parts, useful power, will go almost anywhere a new 4x4 will be driven, look for "seriesII" badge, and less than 160,000k.
(still wish I had my ugly old VP!)
Falcon Wagon with all alloy 6 cylinder - drive well, 10-11 L/100 on a run, roomy for sleeping, cheap parts, great power, will go almost anywhere a new 4x4 will be driven, excellent on gas. One of the best straight 6 motors ever built.
Toyota Camry V6 1998-2002 wagon, quick, reliable, and cheap to run, front wheel drive is fun on twisty gravel roads, and good for well over 300,000ks if serviced.
Note at around150,000k will need new cam belt, and if it has not been changed, drop $1500 off price.
Subaru, had a liberty wagon with a 3.0L flat 6, bit more expensive, but great driving car.
Commodore, Subaru, Ford mondeo. VW
or under 5 years old.
Same as new wagons,
Plus last of the big Ford wagons (if you can get one) or VW passat R36 or diesel.
All good, easy to live with, and good service networks.
Smaller 4cyl jap wagons, last of the Mitsubishi Lancer or Corolla wagons are good.
try a 4 cylinder entelechis with some munkae dual suspension and some ceramic super swiss turbo | <urn:uuid:dea76dbe-8a41-43d2-a162-5295f9bcf695> | CC-MAIN-2023-40 | http://www.skateboardracing.org.au/forum/topics/looking-to-buy-a-new-car-cant-choose-between-a-commodore-or-a | 2023-09-26T04:48:00Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.911594 | 751 |
PPG PAINTS ARENA
STADIUM DUDE’S NHL ARENA RANK: #11
- Location: Pittsburgh, Pennsylvania
- Opened 2010
- Capacity 18,387
- Games attended: 1
- Last visited: 2020
The Pittsburgh Penguins almost left town several times. Kansas City almost had them in 2008. Jim Basillie was going to move them to Kitchener, Ontario (likely two feet outside Toronto Maple Leafs territorial rights) in 2006. Over the course of the team’s first 40 years of existence, rumors tied the Penguins at various times to Las Vegas, Houston, Oklahoma City, Denver and Seattle. But in the end, they were able get a deal to replace the old Mellon Arena, and built a state-of-the-art facility that should keep them put for a while.
The architecture of the building is beautiful, with glass windows along one full side of the arena, and a plaza filled with towering trees surrounding it. It features all the money-making fan amenities needed to help a mid-market club thrive including 2,000 club seats, a fine-dining restaurant, a 4,000 square-foot team store, and one concession stand for every 158 people.
Like in the other Pittsburgh sports venues, you can get the holy trifecta of Pittsburgh blue collar eating here with Primanti Bros (killer sandwiches), Quaker Steak and Lube (wings) and Burgatory. Smokestack BBQ adds another viable option. While Yuengling and Iron City are ubiquitous, you can also find good Pittsburgh craft beer from North County Brewery, Church Brew Works and Southern Tier. And strangely, PPG Paints Arena joins the Honda Center as one of the only two NHL venues where one can’t get a Coke or Pepsi; RC Cola pours here.
The gold, grey and black seats are the most comfortable in the league; in some cases, they’re 24-inches wide. The Highmark Wall of Champions celebrates hockey in the region. There’s a cool Kids Zone offering diversions for youngsters. On the north side of the building are stunning views of the Pittsburgh skyline. And whenever the home team scores, chandeliers viewable from the outside turn bright red, letting passers-by know the good word.
The on-ice product has been particularly good, as the team seems to transition from superstar to superstar. Fan support is strong as witnessed by over 633 straight sellouts that only recently ended.
On the downside, the downtown area around the rink isn’t particularly built up with bars and restaurants: there are a couple of good ones, but choice is lacking. Fans aren’t known for being the loudest in the league. There are a couple of bottlenecks in the concourse design that one wouldn’t expect from a modern rink. And if you’re not staying in a nearby hotel, access can be a little tricky.
Those negative points listed aside, PPG Paints Arena follows in the tradition of Heinz Field and PNC Park. It’s another fantastic facility for a team sporting Pittsburgh’s black and gold. | <urn:uuid:3cf4b9cb-7e6b-4079-9e55-9dcc04b86adb> | CC-MAIN-2023-40 | http://www.stadiumdude.com/pittsburgh-penguins/ | 2023-09-26T07:04:40Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.920562 | 667 |
TO INDIA’S BIGGEST STONE INDUSTRY EXHIBITION
As one of the largest International exhibition on Stone industry, the 12th edition of Stonemart - India Stonemart 2024 scheduled during 1-4 February 2024, would have exquisite display of the world of natural dimensional stones, ancillary products and services comprehensively. Various stakeholders of the industry viz. domestic and overseas producers, exporters / importers, consumers and buyers, experts, technology providers, architects, builders, developers, corporates etc would be present under a global umbrella called Stonemart.
India Stonemart 2024 would prove to be an ideal platform to the participating companies to promote their products, services & re-invent their brand image amongst the consumers from across the globe and establish business linkages with them for enhancing their business horizon and prospects.
Centre for Development of Stones (CDOS) is the organiser and Federation of Indian Chambers of Commerce and Industry (FICCI) is the co-organiser of the event. Rajasthan State Industrial Development and Investment Corporation Ltd. (RIICO) is the Principal Sponsor of the event.
As one of the most admired exhibition, India Stonemart has created a niche in the international exposition scenario. World Class infrastructure, facilities and services are being offered to the participants to amplify their business experience. India Stonemart 2024 would be an ideal destination for negotiating business deals & network with the stalwarts of the trade for doing business. | <urn:uuid:b52f59c7-8247-4e2b-879b-7069cac41224> | CC-MAIN-2023-40 | http://www.stonemart-india.in/show | 2023-09-26T05:04:40Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.933821 | 311 |
*What is Agenda 21? Many equate it with conspiracy theory, but conspiracy theory or not, it is a prevalent issue for many members of our communities. More and more citizens are drawing attention to it in public meetings, be it city councils or planning commissions. Agenda 21 is a real document (see it here), but what drives it is a term that we know much better - regionalism. Whatever we call it, if you do not know about it, you should.
Agenda 21 is a three-decade old, grand plan for global ’Sustainable Development,’ brought to you from the United Nations. George H.W. Bush (and 177 other world leaders) agreed to it back in 1992, and in 1995, Bill Clinton signed Executive Order #12858, creating a Presidential Council on ‘Sustainable Development.’ This effectively pushed the UN plan into America’s large, churning government machine without the need for any review or discussion by Congress or the American people. And it is currently being reinvigorated through numerous executive orders and administrative rules under our current administration.
‘Sustainable Development’ sounds like a nice idea, right? It sounds nice, until you scratch the surface and find that Agenda 21 and Sustainable Development are really cloaked plans to impose the tenets of Social Justice/Socialism on the world.
At risk from Agenda 21;
- Private Property ownership
- Single-Family homes
- Private car ownership and individual travel choices
- Privately owned farms
The Agenda 21/regionalism plan openly targets private property. For over thirty-five years the UN has made their stance very clear on the issue of individuals owning land;
Land… cannot be treated as an ordinary asset, controlled by individuals and subject to the pressures and inefficiencies of the market. Private land ownership is also a principal instrument of accumulation and concentration of wealth and therefore contributes to social injustice; if unchecked, it may become a major obstacle in the planning and implementation of development schemes. The provision of decent dwellings and healthy conditions for the people can only be achieved if land is used in the interest of society as a whole.
Source: United Nations Conference on Human Settlements (Habitat I),Vancouver, BC, May 31 – June 11, 1976. Preamble to Agenda Item 10 of the Conference Report.
As regards the UN, that organization’s problems with America’s appreciation of freedom and self-determination is one that needs no explanation.
In California, the end goals of Agenda 21, under the guise of AB32, SB375 and many other regulations, is being implemented to create plans for sustainable management of ‘open spaces.’ The definition of what is to be considered an ‘open space’ has sparked some heated exchanges between those directing the planning meetings and citizens who want private property rights to be respected and protected.
This type of global plan could not be implemented without a large and well-funded group pushing through its priorities. For that, Agenda 21 has the International Council of Local Environmental Initiatives (ICLEI). And ICLEI is deeply entrenched in America;
ICLEI USA was launched in 1995 and has grown from a handful of local governments participating in a pilot project to a solid network of more than 600 cities, towns and counties actively striving to achieve tangible reductions in greenhouse gas emissions and create more sustainable communities. ICLEI USA is the domestic leader on climate protection and adaptation, and sustainable development at the local government level.
Over six hundred cities,towns and counties in America are members of ICLEI? Do you support your local government agreeing to rules and regulations set up by a UN-based organization that wants private property transferred to government control? If you would like to see if your community is a member of ICLEI, you can visit their website.
In the world of business Agenda 21 is not a free market friend, preferring PPPs or Private Public Partnerships where the government decides which companies will receive tax breaks and are allowed to stay in business. In light of this realization, the cozy relationship between the current administration and GE (a company that paid no tax in 2010) should raise eyebrows. And the WH efforts to tell Boeing in which state they can operate seems to further bolster the belief that Agenda 21 ideals are already making headway in America.
The seeds for Agenda 21 were planted back in 1987 when the writings of Gro Harlem Brundtland (a woman who was first Vice-President of the Socialist International) caught the eye of the UN. Dr. Brundtland wrote a report for the UN called, ‘Our Common Future’ eventually got into the business of environmentalism as a tool to control all the people of the world and establish a global government. The growth of ICLEI and the framework being put in place by supporters of Agenda 21 appear to be bringing Dr. Brundtland’s ideas closer to reality*
For those in the public sector in Southern California, you will find that WRCOG, SCAG ect cite Brundtland and her writings all throughout their reports and philosophies. To have a known, prolific socialist used as a standard bearer for the way that we are to govern is simply not acceptable. For those in other municipalities that are members of similar "regional" governance agencies - just Google the name "Brundtland" with that particular agencies name and we are sure that it will be a real eye opener for you and your peers.
Agenda 21 is NOT a right or left issue. Members of both parties implement it and members of both parties oppose it. It is not a difficult decision. Do you support the freedoms that the Constitution of the United States affords you, or do you prefer the restrictions and mandates from global powers that answer to no one?
One can argue that the treaty was never truly "ratified", but what does ratification really mean if we are implementing everything anyway? Our current governments, federal as well as local, are doing many things that have no oversight, no accountability and no "ratification" ... just look at how many Executive Orders have been signed in the last 4 years alone. It worse than not having permission - our cities, through entities such as ICLEI, League of Cities ect are PAYING to have global mandates thrust upon us.
And on the other side of the coin - we have the APA (American Planning Association) taking their entire curriculum, programs and procedures straight from the UN. At the APA International Conference 2012 in Los Angeles, CA, the majority of the speakers were all prominent UN leaders. (Members of our team attended this conference and a full report can be seen HERE). The planners AND developers are drinking from the same poisoned well. The developers come "selling" what they think the planners and councils want to hear. But have you ever asked a developer WHY he is jumping through all of these hoops? Does he really think that if he puts a home on a 4,000 sq ft lot versus a 7,000 sq ft lot that he will save the atmosphere AND the fairy shrimp? Probably not. He just needs to get his project through, and he knows all the feel-good verbiage that will, hopefully, expedite the process. This is where staff and electeds can make the difference. Really go through these General Plans and UNDERSTAND what the regulations, zonings, mandates are REALLY about. Don't just include words because it is what "everyone else is doing". The goal of regionalism is to make everyone "the same". Do you really think that is what the members of your community want? To be same as the neighboring town? Is that what you want?
America is being punished for being productive, successful and, dare we say it , RICH, and we are begging for the punishment (redistribution of our wealth).
More and more people are waking up to the dangers of the mandates and the regulations and pushing back against them. The question now is, will you?
SEE NANCY PELOSI AND YOUR CONGRESS SUPPORT AGENDA 21 ON THE HOUSE FLOOR
AND IT IS NOT JUST THE DEMOCRATS:
George H.W. Bush was in Rio for the ceremonies and happily signed on for America so that our Congress did not have to spend the time reviewing the treaty and learning how America would be destroyed from within -- that protecting the environment would be used as the basis for controlling all human activity and redistributing our hard earned wealth.
*Our thanks to The Blaze for the concise explanation! | <urn:uuid:936d8363-b2a8-4425-9c7d-9d01c061b5a2> | CC-MAIN-2023-40 | http://www.sustainablelibertynow.org/agenda-21-myth-or-fact.html | 2023-09-26T05:39:34Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.956241 | 1,767 |
February 02, 2023
Listen to Podcast Episode:
On this episode of Ask Suze & KT Anything, Suze answers your questions about debt, gaining access to a deceased loved one’s accounts, T-Bills, starting out saving money and more!
Suze: February 2, 2023.
KT: Where's the time going, Suze?
Suze: You always ask that question you always do anyway. Welcome everybody to the women and money podcast as well as everybody smart enough to listen.
KT: This is ask KT and Suze...
Suze: Anything anything. And if you want to ask us anything just send in your question to ask Suze podcast, that's S. U. Z. E. podcast at gmail dot com. Listen to me, a lot of you are sending in really really really really really long questions again... isn't gonna happen. Thousands of you are writing in
Suze: and so if you want a question answered it has to be short, really short. Or just not gonna happen anyway. I'm excited. You know why
Suze: Right well I'm not exactly excited that the 49ners seriously got obliterated
Suze: right on last sunday but I am excited that the Kansas City Chiefs won. I like that.
KT: Because your boyfriend is Mahomes.
Suze: Mahomes, I call him, what do I call him?
Suze: That cat's meow. Anyway. So but also Alliant Credit union has raised their interest rates to 2.95%.
KT: Almost 3%. That's incredible.
Suze: On the ultimate opportunity savings account. I love that a lot. Also I just want to tell everybody that many of you have been worried that you're not going to be able to participate
Suze: in the three and six month C. D. s that we're going to be offering in about one month from now, through Alliant Credit Union. However you will be able to because why Alliant has decided
Suze: that everybody will be able to either purchase these you know in your Ultimate Opportunity savings account and even if you don't have one whatever account...
KT: You happen to have just to be a member, It's just that simple.
Suze: Just that simple like KT said and you go to my alliant dot com. M Y A L. L. I A N. T dot com to become a member.
Suze: There you go. You got questions for me today.
KT: I do. Are you ready?
Suze: I'm ready. You looked a little sad. Are you sad today?
KT: Oh no no I'm not sad but I wanted to just tell the listeners that when I looked through all of these emails I think it's important sometimes to balance out
KT: the tragedies with the happy ones or the questions that are very simple and the questions that are very complicated. So this complicated. No it's a sad one. It's not at all complicated for you but it's a very sad email for, you know for Pat who sent this in and I want to share it. I I really felt my heart went out to you, Pat
KT: And Suze, you're gonna hopefully help her and anyone else that may ever experience something this tragic. Hi Suze and KT. I wish this was a happy email but it is not your podcast was a must before tragedy hit my life last October 16, 2022.
KT: My only child ended his life on that day.
KT: I feel as if I have died that same day with him now I am struggling with getting my son's very few possessions in order. He was 21 at the time. He lived with me all his life, never married nor children. He did not leave a note or anything in writing.
KT: He didn't have a will or any other document where it would state his wishes. He didn't even add anyone as a beneficiary to his checking account, investments or life insurance policy. This was all through his job by the way and again, he probably didn't know about that. All I knew he possessed was a checking account and two brokerage accounts, Fidelity and Robin Hood
KT: and his 2006 car that was paid for
KT: a survivor's financial advisor through his former employer told me I could run his credit report to find out if maybe he had other accounts open. I can't do that. Experian asks for proof that I am authorized to act on his behalf. Such as a copy of a legal document with the court seal indicating I am the executor of the estate. And how do I get that?
KT: I am so lost. I just want to put an end to all of this. I want closure, Suze. His dad and I were able to receive the life insurance benefit after I filed all the needed documents with the insurance provider. But for these other accounts they're making it so complicated.
KT: She said, Suze I just don't have the brains or the stamina to do this. What advice can you give me? What should I do?
KT: So let's start with the first thing Suze that anyone dealing with a death a sudden death needs to do.
Suze: Well what makes one's life easier in this situation. Pat, I'm so sorry, I'm sorry I'm sorry for your loss. You know what can I say? Other than that there's really nothing that will heal your heart from this one for a while. If ever.
Suze: Let me just see if I can take a larger view point on this. Which is what makes this process whenever it happens at any stage of life easier is when
Suze: a few things have happened. Either the person has created a will saying where everything is to go who's to be the executor and things like that. Or a living revocable trust. You all know that I love the must have documents and I think that's something that all of you should have. However in this particular situation, whenever you have an account like a 401(k),
Suze: all you have to do is always designate a beneficiary and then it will go directly to that person. If you have a bank account
Suze: then you can do the same thing. It could be a transfer on death account or a pay on death account. So you've named somebody. So it never has to go through probate, same thing with life insurance. Life insurance should always have a beneficiary named. When you don't have a beneficiary named as in this case Pat. Then everything is dictated by what's called intestate succession.
Suze: So when somebody dies without a will and they have assets that that do not have a designated who, it's to go to pay on death or transfer on death name.
Suze: Then you are governed by the intestate laws of the state that you live in.
Suze: Because your son lived with you, he did not have any siblings, anything, any you know spouse, any children, nothing else. You and his father are entitled to 100% of everything that he has. So you now have to prove that number one he's dead. So hopefully you got a certified death certificate.
Suze: I'm not exactly sure if you did or not. But again for an overview on this for everybody. If ever you experience a death of a loved one,
Suze: you have to immediately get a certified death certificate. And that is where you have a death certificate that has been certified. The easiest way to do that is through the funeral home or the mortuary. It usually will cost 10 or $20 for a certified one. You should have at least 10 of them, preferably 20. As time passes like in this case since it was last October,
Suze: you can't go to the funeral home anymore. It's got to be done right away. So then in this case, what you would do is you would go to the Bureau of Vital Statistics and that is where you would apply to get a certified death certificate. But first you are going to have to be appointed by the court in your state
Suze: that you are the executor and that you have the right to do all of these things. Now I know that Pat, you you don't have a brain for it. You say how would you at this point in time you're not in your brain, you're in your heart and your heart is broken and when your heart is broken your brain is broken as well.
Suze: And that's true for everybody because you can't think straight because you are hurting so badly. Therefore
Suze: you need to just take your time. You need to just do this step by step. You might want to go to the county of vital records and see if you could get everything you need there. But you may very well need to do what? Go and get it a sign where you are the executor. You might need a lawyer to help you do this. I think that would be the absolute best thing for you to do since it's just so difficult for
Suze: you. But little by little those are the things that you have to do and then you contact the brokerage firm, his bank, everybody and all of that will be transferred to you. Just that simple. KT, I have to just say when you die in intestate, let's say her son right? There were siblings and parents.
Suze: It might be divided between all of them. It's very for every state has what's called the rules of intestate succession, which is how they determine the assets are to be split if you die without a will. So that is something all of you that you don't want to have to go through. Trust me on that one. I know sometimes your kids are young
Suze: and they don't have much. They have a car. Maybe they have, you know, a life insurance policy, whatever it may be. And you don't think that they need these things. They need these things. 00:11:53
KT: And you need to have the documents in order to protect you and no matter what. Right. Yeah. Alright. Alright. Good. Suze. Thank you for doing that. And Pat again. We're so sorry for your loss.
Suze: Yeah. All right. Next question.
KT: Suze, this next question is from John. Dear Suze and KT. I have a question or two.
Suze: Did you pick that because it was your brother's name?
KT: No, we call my brother Johnny . Okay, so dear Suze and KT. I have a question or two about rollover ira accounts, My husband and I each have a rollover account for our old 401(k)s. He has approximately 12,000 in his
KT: And I have about 30,000 in mine. We are both fast approaching 60 years of age with the market down as it has been lately. A couple of positions in our rollover accounts are looking pretty good
KT: as far as adding to a position at a much lower cost basis. Are we allowed to contribute to these accounts since they are funded with pretax dollars? Are these accounts subject to RMDS as our 401()s are? When we reach a certain age are rollovers in 401(k)s case treated the same way?
Suze: Yes rollovers, traditional rollovers
Suze: meaning pretax rollovers and pretax 401(k)s, traditional 401(k)s are treated the same way that if you were born between 1951 and 1959 then at the age of 73 is when required minimum distributions start
Suze: 1960 and later. You can wait till you are 75 years of age. However your first question is can you contribute to this? If you are earning money
Suze: and you make new contributions into this, that would be then a pretax contribution. It would be a traditional IRA and you can put money in it because you can combine your ira rollovers with your iras and all of that fine. As long as they're all pre tax.
Suze: However if you want to put more money into it, why not just open up a Roth IRA and do it through there. If you qualify for it income tax wise. So that's what I would be doing. That would be smarter for you than putting
Suze: more money into a pre tax situation, if you ask me. Next question, KT
KT: OK. This is from Amy Lee. Hi Suze and KT, both myself and my husband's employers offer Roth 401(k)s but we're not sure if we should be taking advantage of them.
KT: Is there an income level or tax bracket where you would say you would be better off using the traditional 401(k). Thanks so much.
Suze: So a few things and it is actually kind of relates to the last question to that, John asked and first of all, Amy, I have to tell you,
Suze: I don't care what tax bracket I'm in right now. If I could put money in a Roth 401(k) versus a traditional 401(k), I had a company that offered them, oh, you betcha, I would do it. Hands down for two reasons. Hands down a Roth 401(k) now is so fabulous. I can't even tell you why
Suze: Before Secure 2.0 was passed just a little bit ago.
Suze: If you had money in a Roth 401(k), you would have to start taking required minimum distributions out at the appropriate age.
Suze: However, a Roth I R A you don't have to take required minimum distributions out ever. That was one of the main differences between a Roth 401(k) and a Roth IRA now because of Secure 2.0
Suze: you can leave that money in your Roth 401(k) for as long as you want to. And it is no longer required that you take required minimum distributions from a Roth 401(k).
Suze: And that then takes me back to, why are you better off doing a Roth 401(k) versus a traditional 401(k), is because you can just leave it in there for the rest of your life. You can put larger amounts of money in there than you can in a Roth I. R. A.
Suze: And anytime you want, you can always convert it to a Roth IRA you just want to make sure that the Roth IRA has been open for at least five years, but no a Roth 401(k) is so fabulous now. I don't see any downside in it at all.
KT: Okay, Go Roth. All right. All right. Next question from Dana. Hi Suze. I'm in my late sixties and I have a small alimony coming to an end
KT: Before my divorce, my husband siphoned all his money and stopped contributing his salary to our joint account. I was in a very violent abusive marriage and everything was controlled by him until I finally had the guts to sign a lifetime restraining order. Good for you, Dana.
KT: And then she said long story short, I ended up with very little in an IRA it's in cash for years because I just don't know what to do with it. I don't want to lose it. So I need some advice. However, there's other circumstances. All of my ex's marital debt was allowed to be discharged years ago in an individual bankruptcy, 00:18:10
KT: The debts became mine. So I followed the same horrible path. I lost my house, which was the only safety net. I had. Suze, what should I do? Now Suze, this this was the reason I picked this question is because I didn't know that can happen. The debts became hers, wow!
Suze: What really is important? Everybody...
KT: I never knew that.
Suze: ...is that when you when you get married,
Suze: this is very important for you to understand, even if your spouse has credit cards in their individual name
Suze: at the bottom of the application it asks, are they married? And when they say yes, then there's a little tiny thing and really small writing that says these debts will then be jointly and severally liable. Which means that if you separate the other person is liable for the debt that that person charges on that individual credit card.
Suze: So that's why I have always asked all of you to please sign a prenuptial agreement before you're married. That states that you are not responsible for any debt occurred after
Suze: the marriage takes place and that you should always make sure that you should know that if your spouse is opening up in individual credit card that that credit card knows that there's a prenup stating that.
KT: So where does she begin with this?
Suze: But it's important for everybody to know because Dana has already gone through this that if you are in a relationship and now you're getting a divorce and any money
Suze: is owed on any credit cards, especially those that were in joint names.
Suze: That those credit cards have to be paid off in full and closed down.
Suze: Otherwise your ex spouse can now claim bankruptcy like Dana's did. And then what will happen is the creditors will come knocking at your door
Suze: and unless you have to claim bankruptcy like Dana did you are going to be the ones to pay those debts. Student loan debt will not as long as they didn't combine their student loan debt. As long as the student loan debt is an individual name, Dana is not responsible for that. However
Suze: now Dana to answer your question which is, you know you have this little IRA it's in cash and it's been that way for years because you don't know what to do with it. Any advice basically you have to know that you feel secure you're in your late sixties here. So you want to make sure that this money is kept safe and sound
Suze: wherever that account happens to be, you might want to ask them, can you purchase Treasury bills three and six month treasury bills right now within that I. R. A. And they will probably say yes to you. And it's those types of investment certificates of deposit, things like that that you should do right now. Okay.
KT: All right. Next question is from Israel...
Suze: Are there gonna be any more sad ones?
KT: I hope not.
Suze: Alright keep going keep going.
KT: Next question is from Israel. On a previous podcast you mentioned to buy T bills on a secondary market since these transactions would entail some fees, Why not buy them through the brokerage account or ready everybody: Treasury direct?
Suze: Israel you absolutely can and should do it that way. I don't have a problem with that at all. Sometimes people like doing it on the secondary market because they know exactly what they're going to get and it's just that easy. And sometimes you can arrange it with your brokerage firm as well on the secondary market that there is no fee. Just to
Suze: depending on your situation. Go on KT.
KT: A similar question Suze. This is from Daniel. Do you have any problem putting emergency savings into short term T. Bills or at least part of it?
Suze: No. Not on any level. If you do three or six month treasury bills or maybe you want to take Alliant Credit
Suze: Union up on their offer and do a three or and or six months C. D. You can do it there as well. And then when you want that money can go into your ultimate opportunity savings account currently earning 2.95%. You might want to look at that as well to do so by the way you all should go to my M. Y.
Suze: Alliant. A. L. L. I. A. N. T. Dot com. And that's where you open up the ultimate opportunity savings account. Alright.
KT: Alright. This is from Patti.
KT: My husband is 65 and on disability. I am 63 and working we have a net worth of about $2 million. Yeah good for you guys. House is paid off. Kids are grown independent and financially stable. And then wait. Patti writes. Yay.
KT: We're cheering you on too Patti. Ar 15 year term insurance has run its course. The renew rate is about four times what we've been paying. How do I know if we still need term insurance?
Suze: By simply asking yourself the question if you died, Patti or your spouse died, would you still be totally financially okay?
Suze: If the answer to that is yes then you don't need term insurance anymore. However, at 63 with a net worth of $2 million dollars, shortly, you're gonna be able to collect social security here and everything. You do not need term insurance. I can already tell you that one. All right,
KT: Suze. This next one is my favorite. This is my very favorite favorite emails from Roz. I'm just starting out. Suze. I'm getting my finances on track. I have $2000 in a savings account and 1000 in emergency cash. Is it worth it for me to even buy a three month C. D. At this point
KT: it seems like I need more money to put in a CD to make the interest gained worthwhile. Is my thinking correct. I just got a small raise at work. I'm planning on using that new income to start and fund a Roth IRA. It seems like everyone else is working with thousands of dollars and I'm working with just penny, Suze.
KT: Not saying the principles don't apply but just disheartening to see my yield on a three month is equivalent to maybe a meal at a restaurant. I need to help with my thinking so I can keep growing my money. So we don't know how old Roz is, but let's assume Roz is about 25. Yeah.
Suze: So you asked me a question in here is my thinking correct.
Suze: It is so not correct, I can't even tell you. More important than the amount of money that goes into a savings or a Roth IRA is time time because of compounding is more important than the amount of money that you actually put in. Believe it or not and I'll just give you an example, let's just say that
Suze: you're 25. That's how old were making her. Let's just say you put in only $100 a month in this Roth. I. R. A a pittance for what probably other people are putting in. $100 a month and you do so for 45 years. Because now 70 is the new retirement age, you're all aiming towards 70. And let's just say over those 45 years
Suze: that the markets went up and they went down. But over those 45 years you averaged an 8% annual average rate of return. In 45 years, you would have about $500,000. However, if you were to do true market returns because I was being conservative there.
Suze: That over all of that time, 45 years, let's say you just averaged 11%, you would have $1.2 million.
KT: Amazing right? Compounding
Suze: And that's at $100 a month. Now
Suze: this is what I would do if I were you, I really want you to take me up on the ultimate opportunity savings account at Alliant Credit union. And let me just give you an example as to why.
Suze: Let's say you took $100 a month. Forget the Roth ira whatever it is, you just took $100 a month and put it in one of these accounts right now that are saying they'll pay you three or 4% or whatever, right? And usually those are accounts that require very high minimums and they're kind of just suckering you in and will change the rate in my opinion. All right. But just let's say you do that
Suze: after one year, you would have 1200 you put in 1200 $100 a month. For 12 months, you would have $1225. So you would have earned $25 in interest over that year at $100 a month. If some institution was paying you 4%
Suze: if you put $100 a month into the ultimate opportunity savings account at Alliant Credit Union where they're currently paying 2.95%.
Suze: At the end of 12 months, you would have $1,319. Now, why is that? That is because with the ultimate opportunity savings account, if you put in $100 a month every month for 12 consecutive months, Alliant will give you $100.
Suze: So that $100 makes a serious difference. It comes out to be an 18% return on your money versus a 4% return if you go somewhere else. So, again, my aliant.com. And look for me is where you need to go. That was one of the reasons that we started the ultimate opportunity savings account.
Suze: So you should take advantage of it, my girlfriend. All right.
KT: You know what time it is.
Suze: You know what? I know I have an interesting one for you.
KT: Okay, I'm ready.
Suze: All right, so this one is from Jaffa. Alright. She says Suze, please don't be mad at me. I love that. I'm 69
Suze: but two months ago I foolishly requested to collect my social security benefits. I don't really even need the income from it. I believe my first check would arrive in february. I know it's dumb, but it's done already.
Suze: So, the question to all of you, because quizzie time is all about. Can KT answer this quizzie but can all of you answer this quizzie as well? Because these are the things that you need to know. So KT can Jaffa,
Suze: She's already started. It's going to be here. It's already probably here at the first of this month. Now is there anything she can do about it?
KT: I don't think so.
Suze: So she's stuck?
KT: I think so.
Suze: Alright. Is that your answer? Because she already claimed
KT: Yeah. Unless she defers it.
Suze: Can't defer it. She already claimed.
KT: So if she already claimed that she's it's done. Done and done.
Suze: Alright. Alright. Is that your final answer?
KT: I think so. I think you're stuck. I think you just have to take the money.
KT: Okay. So what can she do?
Suze: Alright everybody you have 12 months...
KT: to change your mind?
Suze: Yes. From the time...
KT: I didn't know that.
Suze: Well, that's why I picked this.
KT: Did any of you know that? No. Did I mean is this something?
Suze: KT, are you defending yourself again? Let me answer this and tell everybody what they need to know, more than smoothing your little feathers here because you gotta (wrong answer)
Suze: Anyway, I'm sure everybody else did as well. So that should make you feel bad. You have 12 months from the time that you claim social security to let them know. You want to give them all the money back and start over now in this situation. Jaffa, what I would be doing if I were you ready, I would be taking this social security check that you do not need.
Suze: And I would be investing it in where either a three or six month treasury bill or C. D. Whatever state you're living. And makes sense to you. And at the end of the time, maybe in seven or eight months from now where that money has earned interest. I would call them and say I've changed my mind.
Suze: And it used to be now, maybe they've changed this. But I don't think so. It used to be that when you paid them back, you paid them back without any interest. You just gave them the money, which was the amount of your social security check. So you then pay that back and then you started when you are 70. So,
Suze: If you can do that. And that makes sense to you. Great. If that's too much trouble for you and you don't need the money. Do me a favor. Just call them back. Tell them you don't want it now and you're going to be starting it at 70. Just that simple. But those are two things that you can do and you should do.
Suze: All right, KT...
Suze: what's that look for now?
KT: Well, now what?
Suze: It's over
Suze: Now we go feed our chickens.
KT: Let's have breakfast and feed the chickens.
Suze: The chickens haven't been coming every morning. Makes me very sad.
KT: I have to show everyone that the chickens are eating out of your hand. I know, but will see little seeds. She orders some really good organic...
Suze: For two mornings in a row, they did not show up.
KT: I think because they're getting big now they're kind of on their own.
Suze: ...and I sit there and I go chicky chicky chicky come here chicky chicky chicky and nobody comes. I wait for like a half
Suze: an hour. The sun has just come up and I'm like, where are you? And so sad do we lose...
KT: Yea, I think so, they are like teenagers now.
Suze: We see that eating other places, but no more. Are they coming to us? All right, So, KT, are you ready to take us out? Alright, So there's only one thing that we want all of you to say every single morning when you wake up and it is
Suze: as follows today, wherever I go, I will create a joyful world. Alright, Everybody say it every single day and make it come true. Until Sunday. There's really only one thing that I want for you. I want you to stay safe
Suze: and for you to never stop yourself from being who you are meant to be and what you want to do. All right, See you soon. Bye bye. Everybody.
Get Suze’s special offers for podcast listeners at suzeorman.com/offer
Join Suze’s Women & Money Community for FREE and ASK SUZE your questions which may just end up on her podcast!
To ask Suze a question, download by following one of these links:
CLICK HERE FOR APPLE: https://apple.co/2KcAHbH
CLICK HERE FOR GOOGLE PLAY: https://bit.ly/3curfMI | <urn:uuid:52a4e43e-ea8c-4aaf-9f1a-111c6c7a582b> | CC-MAIN-2023-40 | http://www.suzeorman.com/blog/Podcast-Episode-Ask-Suze-KT-Anything-Am-I-Responsible-For-My-Exs-Debt | 2023-09-26T05:16:30Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.979679 | 7,608 |
Ya that’s true. Hutch is heading for a change of name (AGAIN) thanks to the deal between Vodafone and Hutchison Whampoa. Vodafone, which now has about 67% in the company now wants to rename Hutch to a worldwide known name Vodafone. This also shows the thoroughly enjoyed majority of Vodafone. Vodafone’s worldwide CEO, Arun Sarin will be coming down to India to have the new name launched.
People still remember the logo of Orange, which was used by the company, which was then changed to the existing Pink Hutch logo. That too is short lived as the name comes with a change in the logo too. The Hutch logo would be replaced by the international logo used by Vodafone.
The launch is scheduled for this week and we really don’t know what would the response of the existing users. Would they accept the new avatar or switch over. That totally depends on the positioning of the new brand. Do tell us what’s your say in this matter. | <urn:uuid:264d77f6-2210-4bdc-b5ca-a3e65476392c> | CC-MAIN-2023-40 | http://www.telegyaan.com/2007/09/19/orange-tha-hutch-hai-aur-vodafone-rahegasoon/ | 2023-09-26T06:41:32Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.96924 | 225 |
The students of MSU's School
The students of MSU’s School of Film and Photography have come together to present their senior thesis photography projects. Please join us for hors d’oeuvres, live music, drinks, and art in The Grand Ballroom.
(Thursday) 6:00 pm - 10:00 pm
The Baxter Ballroom
105 West Main Street, Bozeman, MT 59715 | <urn:uuid:d0f6c92d-3acc-4de0-9a7b-e217858d5371> | CC-MAIN-2023-40 | http://www.thebaxterhotel.com/events/msu-senior-photography-exhibition/ | 2023-09-26T05:43:06Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.90287 | 103 |
In Rajasthan we can see many Attractions.Its also Largest State in the Indian Union. In this package we can enjoy at New Vidhan Sabha, Birla Mandir, Rajasthani dinner, dance with complete rural atmosphere in an ethnic village, Jal Mahal, Hawa Mahal (Jaipur), Museums & Temples of Bikaner, Sightseeing trip of forts, havelis, Gadsisar Tank at Jaisalmer, Mount Abu, City Palace, Bagore Ki Haveli, Temple Pratap Smarak at Udaipur.
Day 1 Arrive in Jaipur
You will be received at airport/railway station and transferred to the hotel. By the evening we visit the modern attractions of the city which includes the Birla Auditorium, New Vidhan Sabha, Birla Mandir and Jawahar Kala Kendra. Later we experience the Rajasthani dinner, folk music and dance with complete rural atmosphere in an ethnic village.
Day 2 Jaipur
After breakfast we drive out to explore the well planned city of Sawai Jai Singh II still alive with Colour, Joy, Regality, People, Art and Culture. We visit the busy Bazaars, the Hawamahal, City Palace and Jantar Mantar. After lunch we visit Amber Fort & Palace, Jagat Shiromani Temple and pass through the scenic Jal Mahal. Overnight at hotel.
Day 3 Bikaner
We reach Bikaner by afternoon and check in at hotel. Afterwards we visit Fort, Palaces, Museums and temples of Bikaner. By the evening we take trip to the prestigious camel breeding farm. Overnight at Bikaner. Overnight at Bikaner.
Day 4 Jaisalmer
Reach Jaisalmer by afternoon and check in at hotel. We take a half day sightseeing trip of the fort, havelis, temples and Gadsisar tank. Over night at Jaisalmer.
Day 5 Jodhpur
Upon arrival check in at hotel. Soon after we climb up the Majestic Mehrangarh Fort and explore its every nook & corner. We also visit the Jaswant Thada, Ummaid Bhawan Palace Museum, Clock Tower and Markets. Overnight at Jodhpur.
Day 6 Mount Abu
After Breakfast continue to Mount Abu – one and only hill station of Rajasthan. Upon arrival check in at hotel. Later take tour of Mount Abu to cover Delwara Temple, Nakki Lake, Tod Rock and Sunset point. Overnight at Mount Abu.
Day 7 Jodhpur
At Udaipur, we visit the City Palace, Bagore ki Haveli, Jagdish Temple, Pratap Smarak, Saheliyon Ki Bari and Bhartiya Lok Kala Mandal. Overnight at Udaipur.
Day 8 Jodhpur
You will be transferred to Airport/Railway station to connect your onwards journey.
Just fill out the information below and we will be in touch with you shortly. If you need immediate assistance on this package, simply dial at +91-9876552277 | <urn:uuid:6ae3d57f-e7d5-4fdd-ad3d-d5b96945a326> | CC-MAIN-2023-40 | http://www.travelthegalaxy.com/india/jaipur/king-of-royalty-rajasthan | 2023-09-26T06:58:06Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.878707 | 675 |
Thanks in the direction of the physically demanding levels of competition, individuals are even more almost certainly toward make investments inside of apple cellular or apple iphone alternatively of other alternatives. It presents an a lot easier and further more easy method in direction of get hold of the fantastic DIY Hobbies. It can guidance yourself in the direction of fork out your amusement period exquisitely, and there are a good deal of option attributes within it Deliver.
Several players are contemplating smartphones alternatively of other solutions as they supply a smoother gaming practical experience with no lags. It is paramount in the direction of decide for these kinds of an incredible substance as an alternative of other Ideas. The apple iphone is a huge competitor of other smartphone producers readily available within the marketplace. If on your own have to have towards come across far more pertaining to it, your self should really go through the after information and facts.
Digital camera: –
The major motive guiding apple iphone’s large good results is that the creators are promoting innovative digicam excellent. With the assistance of this sort of high quality, oneself can simply click the revolutionary illustrations or photos by yourself can smoothly favor prioritizing images as a interest.
These Do it yourself Hobbies can guidance your self toward ease strain versus your life, and the panorama element it letting individuals in direction of snap 240-level and numerous megapixels are Offer there for consumers.
Far more capabilities: –
The apple iphone customers are well-informed within just using the admired amenities and further attributes. In this article yourself can check out the existence of innovative features that are hardly ever obtainable somewhere else. Furthermore, the creators of these kinds of an remarkable material are advertising a voice-triggered element together with Siri. It will operate miracles for oneself, and this guidance can avoid the chaos of accessing a lot more characteristics upon the cell.
creators of these types of an remarkable cellular phone can offer you progressive features. Listed here oneself can obtain the cost-free iCloud services that is best for storing information and facts, songs, and even more. These kinds of qualities are providing people in america some essential purpose toward decide for apple’s cellular telephone in its place of other Strategies out there. | <urn:uuid:d35573ed-1916-42bf-b374-7e1db70964df> | CC-MAIN-2023-40 | http://www.troveta.buzz/2022/10/17/what-are-the-basic-added-benefits-of-apple-cell/ | 2023-09-26T06:39:58Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.922161 | 463 |
Oaxaca, Chiapas, and Nayarit line up for consistency in supply
By nature, transitions can be tricky. Shifting from the southern regions to the northern regions is typically unpredictable and complex. This year, it is proving to be exactly that.
The southern regions have produced a good amount of fruit, mostly on the smaller side and mostly because people like us (Crespo) have strategically increased our orchards there, in order to gain greater volume earlier, capture a bigger percentage of market share immediately, and jumpstart consumer demand sooner. There have been complexities as usual but we maneuver through them fairly well, mostly because of the direct-trade relationships we have with our customers, and the communication and exchange of information on the challenges and opportunities in advance allowing us to together, strategize, knowing each customer and region has different needs.
The Crespo Organic mango program is currently situated in a good place as we transition to the northern regions (aka the volume super-producers). Nayarit and Sinaloa have a greater production, with more advanced farming operations and generally higher yields with more varietals. Their costs/selling prices tend to be lower and, thus, much lower, more incredible consumer price points are doable. Our southern region will continue to sustain the transition so fill rates stay intact and the focus can be on upping demand, while supply builds.
The Nayarit and Sinaloa peak production from June to August happens to coincide with the American summer – long, hot days that make mango-eating almost mandatory for consumers, especially as more experience what we call #MANGOJOY. Mango consumption is on the rise, and the northern regions bustling volumes deliver mangoes at the perfect timing, even if or when they are early or late! This two to three month window is fairly predictable, with the little details making for minor adjustments.
Last year the transition happened during the global shutdown and COVID-19, bringing extra confusion and uncertainty. This year the main issue is the draught that has been fairly consistent throughout the entire mango season from Ecuador and Peru, all the way up Pacific coast to Oaxaca, Chiapas, Michoacán, Jalisco, Nayarit, Sinaloa… and will be seen ( is seen) all the way up into the California mango crop.
This season, like the last few, Crespo Organic has more overall volume. Over the last several years, we have been expanding our orchard volumes in each growing region to keep up with our own increased demand, gaining market share on both the CV (RCF brand) and the OG side.
We will pack more fruit this season than prior seasons, but there has been and will continue to be an overall decrease in yields for Mexican production because of the drought. Fruit will be smaller, but we experienced that last season, too, so we are ready.
The transition for the Crespo program should be relatively smooth. We’re beginning to wind down in Oaxaca and still have some time in Chiapas. Our early orchards in Nayarit and Sinaloa are timed perfectly (this year) so we should have no gaps. Volumes are predicted to be ample which means we can keep pricing consistent and focus on increased demands to feed our peak volumes (which are June – July, as usual)! Our focus continues this be – how to move the big volume we always have coming. This is what we call mango mania times!
Crespo Organic Summer Mango Mania #MuchosMangoes is the collision point between our peak production in Nayarit & Sinaloa and the height of consumer demand, summer! The mangoes are priced during this time in order to move volumes. Our goal is to feed many consumers mangoes at delicious price points.
The peak, or collision point, when technically a few of the larger growing regions and sub-regions overlap with production: Jalisco, Michoacán, El Rosario and Escuinapa (Sinaloa) should begin around the first or second week of June, which is why many in the industry (on the CV side) are saying by mid-June there will be a lot of mangoes. This is true, and it is also true that a lot of them will be small, thanks to the seasons draught.
Here are the details per region to give you a better micro look at the transition details:
Oaxaca is winding down as we speak. Most production there has finished, and there are only a few shipping from here now. Currently we are harvesting organic Kents in Oaxaca, which has been happening at the end of the region’s season for a few years now. It looks like we have another 10-12 days shipping from the area. Ataulfos have finished here.
Chiapas has many little microclimates where our production is located, which have consistently extended the region’s season on both Ataulfo mangoes and round mangoes. We should be picking and packing through the transition north from Chiapas, ensuring plenty of volumes and sizes, as the sizes are a little bigger in the south since it’s the end of the season. Quality continues to be exceptional, and the flavor from Chiapas mangoes is unbelievably sweet and rich this year.
Michoacán Is currently shipping and will ship until around the first or second week of June. Michoacán typically has a lot of small fruit and this season, like last, that is very true. They have all varietals in this region and is one of the only regions left where there is a lot of organic Haden mangoes (my personal favorite). Haden mangoes tend to be very small, one of the reasons most growers have switched out of this varietal. It used to be that buyers wanted small organic fruit, but these days, as price points on organics drop and as consumers are willing to pay more for bigger fruit – demand is high on the large sizes.
Nayarit Has started and we have begun picking and packing Ataulfo mangoes from here. We are seeing excellent quality right off the bat. Nayarit Ataulfos are typically very “clean-skinned” so buyers should be happy as most of the discoloration improves as the Ataulfo drop moves north. The market should reap the benefit as well, as Ataulfo demand jumps up generally this time of year. The Tommy Atkins mangoes should start shipping form this region around May 20 -25th . The Nayarit region produces the Kent and Keitt varietals, as well.
Sinaloa Is on target. The Ataulfo mangoes should begin around the end of May and the round mangoes around the second week of June. We grow and ship 9 different varietals from this region and promote them throughout the Summer Mango Mania campaign: Ataulfo, Tommy Atkins, Kent, Haden, Keitt, Green Mangoes, Baby Mangoes, Manila and Thai Mangoes.
Of course, all things change. That is certain, so we will continue to put out crop updates and industry reports as we get closer to this regions start date.
The basic report is really this:
For now, we do expect to continue with ample volumes of fruit, all sizes, with a lot of smaller fruit and our goal is to promote and sell #MuchosMangoes. | <urn:uuid:132d43df-fd36-41bf-bf9c-721ece5f78b3> | CC-MAIN-2023-40 | http://www.underthemangotree.crespoorganic.com/2021/05/11/smooth-transition-north/ | 2023-09-26T06:31:30Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.959164 | 1,543 |
poke game online www.vipkacakiddaa.net A scam is a type of fraud. Mass marketing scams are the most common. According to the Office of Fair Trading a mass marketing scam is a 'misleading or deceptive business practice where the person receives an unsolicited or uninvited contact (eg by letter, email, phone or advertisement) and false promises are made to con the victim out of money'.
What is the impact of scams
Every year, three million people fall victim to scams (losing an average of £850 each and sometimes a great deal more). As well as losing money, being taken in by a scam can be very distressing for the victim and their friends and family.
For chronic victims it can take over their lives with some individuals receiving up to 200 letters in just one week, all of which they feel the need to respond to.
Scam victims are often not aware or are afraid to admit they have been a victim of a scam. Fewer than five per cent of people report scams to the authorities.
What to look out for
- common scams include claims that you have won money and it is being held in a holding company; somebody has left you an inheritance that you need to claim; or clairvoyants claiming they can stop bad luck and direct good luck your way. All will require a small payment in advance (followed by more and more payments with no 'prize' ever materialising)
- they will appear official (that is their intention). For example, claiming to be solicitors or from the government and will use legal and formal jargon. Letters will be addressed to you personally to make you feel special
- once you have replied to one scam letter you will receive more. If you are receiving 3 letters a day offering superb prizes it is likely your details have been added to a 'suckers list' being shared between scammers
You can view videos about scams and victim stories on the Think Jessica website.
How to spot a victim of a scam
People find it hard to believe they are being conned. Scammers are full of promises that they never fulfil. Victims will become secretive (through embarrassment or scammers telling them not to talk to anyone). Often victims are lonely and have fallen out with friends and family having been challenged about responding to scams.
Common tell tale signs amongst victims are large numbers of letters being received daily. They will also be sending lots of cheques or postal orders, and telephone bills may be unusually high due to the dialling of premium rate numbers.
- Age UK website
- Age UK free advice line 0800 678 1602
What to do if you have concerns about somebody
If you have concerns that somebody you know is responding to scams, talk to them about it. If they would like the scams to be investigated, they can send the letters free of charge to Royal Mail.
If they just want the letters to stop, they need to 'return them to sender' saying 'not known at this address' and the scam letters should stop quite quickly.
If gentle persuasion does not prove successful in stopping them from responding to the letters, we are able to contact them for you to give them advice. Please contact us and we will discuss the individual's circumstances. Action Fraud can also refer people to Victim Support.
Often people who have become trapped in a cycle of responding to scams have additional support needs and if you think this is the case, you can also contact the County Council’s Adult Safeguarding Team to see what additional support could be put in place. Some practical day to day assistance might also be available from local community navigators. | <urn:uuid:801dae41-67e5-4b0d-a8a0-4f9ccfb6cf37> | CC-MAIN-2023-40 | http://www.vipkacakiddaa.net/residents/community-protection/scams | 2023-09-26T05:49:57Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.967409 | 750 |
Fort Hartsuff State Historical Park
A while back Harland and I zipped up to central Nebraska to visit a restored military fort on what was once the western frontier. The fort was started in 1874 for the purpose of protecting settlers during Plains Indian Wars.
There are nine restored buildings to tour, all constructed primarily of concrete. The buildings are arranged around a central square or parade ground, so we started in one corner and worked our way around.
First we stopped at the Barracks where the soldiers were housed.
Each bunk consisted of a simple mattress on wooden slats. Didn’t look too comfy. But Harland thought they were just right.
Next we visited the Mess Hall,
and the Fort Kitchen.
A vintage “Cooks Creed” poster hanging on the wall proclaims, “Better wear out your pans with scouring than your stomachs with purging; and it’s less dangerous to work your elbows than your comrade’s bowels.”
Next was the first of several buildings which housed the officers and their families and servants. Each building was a duplex.
Inside were small but homey rooms. Officer’s wives entertained frequently, and so the Officer’s Quarters were the formal social center of the fort.
Up next is the Hospital.
The Hospital Steward’s (male nurse) quarters were a single room just off the main hospital floor so he could be near the patients.
Up next is the Quartermaster Stables.
It held stalls for 40 horses, a room for saddles and harnesses, and a forage room.
Up next is the Laundry.
There were three laundresses at the fort. They were provided living quarters,
and collected $13 per month from each soldier to wash his clothing. This fee was deducted from the soldier’s pay and given directly to the laundresses. Doing laundry was a three day job of mending holes, treating stains, washing with soap and a scrub board, ringing out with hand crank wringers, boiling to kill lice, rinsing, bleaching, hanging on a clothesline to dry, and finally ironing.
Up next is the Bakery. Each soldier was entitled to 1 pound of bread per day, so bread was baked twice per day, 365 days per year.
The baker was given living quarters for himself and his family, and paid for his labors.
Imagine how uncomfortable these rooms must have been in the summer right next to the wood fire heated oven.
Finally the last building was the Guardhouse.
It was used to contain prisoners- soldiers who were serving for liquor or gambling violations, and sometimes for taking leave without authorization. Cells could be quite small, in fact some were just a large wooden box.
The fort was only active for seven years. When the railroad came through the area, the fort was no longer needed, and it was abandoned in 1881. It was then sold to the Union Pacific Railroad, who intended to start an immigrant center there, but that never materialized. In 1897 the site was bought by local investors who used it for a farm headquarters until 1961 when it was donated to the state of Nebraska. The buildings had fallen into disrepair, but were restored back to their original condition, and today visitors can tour the buildings, see living history exhibits, and talk to period re-enactors.
[ad name=”Google Adsense”] | <urn:uuid:e2f702e5-3a09-44d9-bb72-b1a13c94b430> | CC-MAIN-2023-40 | http://www.windowontheprairie.com/2011/08/30/fort-hartsuff-state-historical-park/ | 2023-09-26T06:19:52Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.981801 | 725 |
Get the Books:
Window Seat Europe
Reading the Landscape from the Air
by Gregory Dicum
Publication Date: October 1, 2006
Contact: Johanna Brown, Senior Publicist, Chronicle Books
Ordering Information: 800/722-6657
About the Author
Gregory Dicum writes about food, travel, and the environment. He has written two books: "The Coffee Book: Anatomy of an Industry from Crop to the Last Drop" (The New Press, 1999 and 2006), and "Window Seat: Reading the Landscape from the Air" (Chronicle Books; 2004), and followup, "Window Seat Europe" (Chronicle Books; 2006).
Gregory has appeared on numerous television and radio shows, Canada's CBC Newsworld and San Francisco's KRON, and NPR's "Talk of the Nation" and "All Things Considered."
Gregory has written for numerous publications including the New York Times, Harper's Magazine, Salon, Travel + Leisure, Decanter, HotWired, New York Magazine, Mother Jones, Gastronomica, and others.
Questions about Window Seat.
How did you get the idea for this book?
What is your favorite flight?
What are people most interested in from above?
How is the view from above different over Europe and North America?
What is the most interesting thing you've seen from above?
How can you figure out what you're looking at from above?
Why should we look out the window when we're flying?
What are those round things?
Most straight lines on the ground were created by people.
Plants grow differently on different sides of mountains.
In the French countryside, you can still see ancient roads that predate the Roman empire.
The Iron Gate is Europe's most dramatic natural feature.
It's easy to spot cork-producing oak woods: look for swirls of trees on Iberian hillsides.
The ancient salt evaporating ponds on Ibiza are often tinted red from natural salt-loving bacteria.
Poland's landscape of narrow, "long" lots is the same as it was centuries ago. In other Eastern European countries, Communist-era collectivization erased these patterns.
You can still see the Iron Curtain from the air--but it doesn't look Iron at all: look for forested areas, strange parallel roads, and cuts through the woods.
Piraeus, the port of ancient Athens, was the first city in the world to have its streets laid out in a grid.
High resolution images suitable for printing.
Click on each image for a high resolution version suitable for printing. If you need more images, please contact Johanna Brown.
Gregory Dicum, the author of the Window Seat books, looking out the window high above the Balkan Peninsula.
Gregory Dicum, the author of the Window Seat books, in San Francisco.
The cover of Window Seat Europe.
The cover of Window Seat. | <urn:uuid:ea27f929-576c-4896-97a7-9bdfebd1bc06> | CC-MAIN-2023-40 | http://www.windowseat.info/media.php | 2023-09-26T04:39:13Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.917974 | 683 |
Happy 2014! While all the buzz about new year’s resolutions continues, you can tune into my “Staying Started” episode for some tips about keeping strong with the promises we’ve made. This episode, I’m kicking off the new year with a dose of gratitude. My guest this week has powerful, pragmatic suggestions for keeping a gratitude journal.
Lisa Ryan is an author and keynote speaker who emphasizes the importance of appreciation. She shares some incredible stories about how thanksgiving has transformed her own life. You can watch some of her videos on YouTube here. Her profound teachings are also featured in the movie The Gratitude Experiment. Her company, Grategy.com offers a variety of ways to fill your life with the health and healing power of gratefulness.
Meanwhile, during this episode’s various stages of production, I was attending the Ninth Annual People’s Choice Podcast Awards in Las Vegas, so the lesson on gratitude was very real for me, as I lived through the suspense of finding out whether or not JournalTalk received the “Health & Fitness Podcast of the Year” for 2013. You’ll have to listen to find out! (JournalTalk, Episode #23, January 13, 2014)
Audio Editing: Netrix Marketing
Voiceover: Kym Maher, Tami Egbert & Thomas Gerrard
Logo Art: Wendy Kipfmiller
Click on the “play” button > below. | <urn:uuid:4ca919be-0716-4d38-920c-116559ed765e> | CC-MAIN-2023-40 | http://www.write4life.us/grategy/ | 2023-09-26T05:56:29Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.928062 | 315 |
The biggest collection of Mature Sauna Orgie
We offer you delicious Romantic Sex With Her Boyfriend
He said, lengthy before agreeing to derive bang. Then i did the neighbors know i opened her blueprint the neighbours butthole. Your room standing there underneath the bar, i could. Freddie and there was sort of pals of the dried catches price as if i am her tongue. Tamara watches me been to the wrists at least 30. After two berkeley coeds encounter, and accept home amateur ff stockings when i could terminate. Gary, but i am the sun that the park wednesday night, and handcuffs. Stay her preserve fun with jealous rage now it suitable. As rapid, i be nude butt with a peculiarly when osama binladin to munch your zipper proceed.
Annette is sexy Then again be support of course i asked me lost numerals of his steaming douche. I was presently outing for colorful and, me. I recognize at the insert found mother had amateur ff stockings handguns. She makes me fancy public picnic and occupy your caress your nut. old man gropes sexy movies Tranny and man in 69 pose Young sister fucks with her boyfriend
ff amateur stockings porn compilation Fucking the 40 years chinese wife of my best friend Two german misstress Solo asshole kelly divine I want more dicks to fuck Busty jodie gassonamateur ff stockings Www sexy garlphotos com Bangla sosur boumar choda chudi Hot ass at the beach kreta 2015 a smoking jerk off encouragement sex tube Kolkata actress xxx video Hd piss loving babes and guys have fully clothed golden shower orgy stockings ff amateurSister begging and sceaming for brothers cum inside her10 Sneha xnxx video hd tube Smoke rock fuck crack
Www xnxx algerien com It starts off with just chill shemale fuck my ass then cum on me amateur stockings ff indian muslim woman sex Carwash babe sneaked and hardcore fucking on tape xxx clips Bif tits 2016 Bus like loke dick
He was lightly the encourage to annoy each other eyes pop the flick when she spoke. She realized the entry amateur ff stockings in flows lightly elephantine bumps formed close, white doll at jane a week. Your daddy dissolved for future before and told her daughterinlaw a seat. | <urn:uuid:f80495ce-4bb5-429f-8e84-713df3d0036f> | CC-MAIN-2023-40 | http://yourhealthykangenwater.com/2020/12/12/amateur-ff-stockings/ | 2023-09-26T06:59:04Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.87824 | 494 |
Students who have been engaged and committed to the Sustainable Development Goals (SDGs) are invited to apply for a scholarship to study at the MCI Management Centre in Innsbruck, Austria. The scholarship provides a tuition fee reduction of up to €10,000. The deadline is on Wednesday 31st March 2021.
The scholarship under the patronage of Excellency Ban Ki-moon allows students engaged in the SDGs to study and develop at a prestigious university institution in Europe.
The scholarship is provided by the MCI Management Centre in Innsbruck, Austria.
This is a privately organized business school, offering study programmes leading to Bachelor and Master degrees as well as executive Master programmes, customized programmes and research.
The funding amounts to up to €10,000 and is intended to cover annual tuition fees.
Applicants will be selected based on the current and past commitment to the SDGs, their impact and future feasibility of the defined projects.
The final decision will based upon the quality of submitted documents and the interview with the jury.
The deadline is on Wednesday 31st March 2021.
Candidates should provide a CV, evidence of language proficiency, a statement of up to 500 words describing their current/past involvement in SDGs and a motivation letter that explains their future goals.
Find out more now about this opportunity.
Another great opportunity for you right here.
All your donations will be used to pay the magazine’s journalists and to support the ongoing costs of maintaining the site. | <urn:uuid:2d39ef26-f2cb-447c-9161-a0e9c7951d4c> | CC-MAIN-2023-40 | http://youthtimemag.com/ban-ki-moon-scholarship-at-the-mci-management-centre-in-innsbruck-austria/ | 2023-09-26T04:48:20Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.940926 | 315 |
According to the Carolina Panthers, the team has given quarterback Cam Newton permission to seek a trade. General manager Marty Hurney met with Newton to discuss his future.
Marty Hurney stated, "One of the distinct pleasures of my career was selecting Cam with the first pick in the 2011 draft," Hurney said. "Every year difficult decisions are made and they are never easy. We have been working with Cam and his agent to find the best fit for him moving forward and he will always be a Carolina Panther in our hearts."
Visit the Carolina Panthers for more details. | <urn:uuid:b7250c45-a51f-4600-b2f5-c113ae42dd3f> | CC-MAIN-2023-40 | https://1029thelake.iheart.com/content/2020-03-17-panthers-have-given-cam-newton-permission-to-seek-trade/ | 2023-09-26T05:14:43Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.97896 | 119 |
WATCH: CNN Attacks 45, Repeatedly, For Paying Respects To 41!
Here are a few samples of what you can find, in the 2+ minute clip, above, from CNN:
"He’s not one to mend fences too readily... I think he’s doing this because he feels he has to do it and I’m also assuming General Kelly has had a big hand in it..."
"I do know from the Bush family that they are very appreciative and think the White House has just bent over backwards, gone to great lengths, been extraordinarily helpful...That said, I just can’t help but wonder if there was a thought bubble over Donald Trump’s head just know, what he was thinking as he stood there..."
"I have to imagine he was thinking, 'how much longer do I have to stand here?'"
"It was somewhat theatrical, uh, in nature, but it's, I, I can't imagine that this is very comfortable for him, these moments and I think it is going to be fascinating to watch the cathedral on Wednesday and how he interacts with these other presidents and how he sits there during these eulogies..."
This proves, once again, that President Trump is damned if he does, and damned if he doesn't... And, don't forget: ORANGE. MAN. BAD. | <urn:uuid:71db820c-c9fb-4c2e-b3c6-49b7c244a686> | CC-MAIN-2023-40 | https://1061fmtalk.iheart.com/featured/kc-o-dea-show/content/2018-12-05-watch-cnn-attacks-45-repeatedly-for-paying-respects-to-41/ | 2023-09-26T06:04:05Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.984406 | 285 |
Animator: Mike Park
Description: The new intern Jamie has constantly been suggesting topics to write in the daily web article and it's causing this individual to vent on another poor intern.
Experience: 2 to 2.5 years give or take.
Time taken: A good amount of hours each day for a week.
(Commenting only available during the rating period) | <urn:uuid:ee8d0613-fe8d-41d5-9208-e487adfa66c2> | CC-MAIN-2023-40 | https://11secondclub.com/competitions/august15/entry/AaTcBq | 2023-09-26T06:55:23Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.920327 | 79 |
An argumentative essay is a written project that is usually assigned to high school and college students. This is a guide for writing a reasoned essay. It starts with defining this document and goes on to tips on how to complete this article and get good grades. Sometimes writing an essay is an extremely difficult task for students, they have to spend more time preparing, and looking for information and ideas.
In cases where students lack the resources to complete a project successfully, they can always turn to the research paper service for better results.
Argumentative Essay Definition
First of all, what is an argumentative essay? An argumentative essay is a type of essay that advances a specific claim regarding a topic. In other words, this paper presents, explains, and defends an argument. Assume, for instance, that the topic is healthcare policy in the United States. Stating that the healthcare system is riddled with problems is not enough, since this is just a descriptive statement. For the paper to be argumentative, it has to make a claim, e.g., a proposed healthcare policy if passed will only make healthcare less accessible for low-income people.
Qualities of a Good Argumentative Essay
Each essay has its unique attributes and how you write your paper largely depends on the instructions and your personal skill level. But there are also some qualities common to all papers. Some of these are discussed below.
#1 Presents a specific and debatable claim
A debatable claim is one of the hallmarks of an excellent paper. A claim that has already been proven to be true is neither interesting nor useful. It’s also possibly boring and definitely redundant. Your claim needs to be timely, relatable, and should rouse your reader’s interest.
#2 Features plenty of evidence
An important aspect of this assignment is the use of credible evidence to support the claim. Improve your paper by including plenty of concrete evidence such as statistical data and established facts. Cite empirical findings from peer-reviewed studies as well as opinions from experts in the field.
#3 Employs sound reasoning
Unlike a persuasive essay that appeals to emotion, an argumentative paper must appeal to logic. It needs to demonstrate that claims are valid because they are grounded on evidence and conclusions are reached through sound reasoning.
#4 Refutes counterarguments
Because the topic is debatable, the opposite position most likely has strong points as well. An excellent write-up addresses counterarguments. Anticipate counterarguments that your reader might bring up and proactively refute them.
#5 Remains objective and non-hostile
Readers will likely be less receptive to your paper if you adopt a hostile tone. Avoid antagonizing your readers. Assume that they are reasonable individuals and appeal to their intellect and common sense.
These are the most prominent qualities of a well-written assignment. There are others more, of course, but focusing on these five should help you produce a top-notch paper.
How to Write an Argumentative Essay
To complete this project, you need to follow the basic writing process. This process always begins with reading about the topic and ends with proofreading the final copy. Of course, the difference is the content that goes into the paper.
#1 Research the topic
Begin the project by researching and reading quality materials regarding your topic. The more you know about the topic, the more likely you will be able to discuss it well. Being clueless about the topic is a recipe for disaster.
#2 Formulate the thesis statement
Once you’ve gathered enough information on the topic, come up with a thesis statement. Always remember that a thesis is a declaration and not a question. It should be concise and specific rather than general.
#3 Create an outline
An argumentative essay outline shows the order and flow of the discussion. List down the points that you will discuss individually to support your main claim, the evidence supporting those points, and the counterarguments and refutations that you will include. The outline can be considered as the skeleton of your assignment.
#4 Write the draft
Expand your outline into a full discussion. Elaborate each of your points in one or more paragraphs. Remember that points need to be discussed in separate paragraphs to keep the discussion coherent.
#5 Revise and proofread
Do not settle for the first draft. Revising your paper once or twice will help you improve its content. This step is essential for clarity and coherence. Finally, conduct a final proofread to ensure that the final copy has no errors and adheres to the prescribed argumentative essay format.
While you are encouraged to follow these steps, do not hesitate to make some modifications in your process. After all, writers have different styles and approaches when it comes to completing a project.
How to Structure an Argumentative Essay
As this paper is still an essay, it needs to follow the basic structure prescribed in academic writing. A good paper should be composed of three main parts: introduction, body, and conclusion. These three main parts serve distinct purposes.
The argumentative essay introduction should serve three purposes. First, it should catch your reader’s attention, and you can do this by adding an effective hook at the beginning of the paragraph. Second, the introduction should provide some context or background information. For instance, you can begin by discussing the details of the topic or issue you are writing about. Finally, it should present your thesis statement, which is the main claim your paper is advancing.
The body is where you present the points and evidence that support your main claim. It is also where you refute counterarguments. Begin a paragraph with a topic sentence stating your point. Then present the evidence that supports the point. Finally, explain how the evidence and the point ultimately support your thesis statement. As for the counterarguments, place them in another section that comes after your points.
The conclusion should restate the thesis but using different words. It should also summarize the main points discussed in the body. Finally, this part should offer the reader final thoughts on the topic. Note, though, that the conclusion should not feature new information or points.
Remember that the structure varies depending on factors such as scope, degree of complexity, and specific instructions. So make sure to thoroughly study your project details so that you can determine how elaborate your paper’s structure should be.
Tips for Getting a Good Grade
Completing an argument essay can be challenging to many due to the need for credible evidence and sound reasoning. But there are ways to increase your chances of getting a good grade. Some tips are provided below.
#1 Choose a fresh topic
The best topics are those that are timely and relevant to the reader. Avoid topics that are outdated, overdone, or simply irrelevant. Know and understand your reader so that you can choose a suitable topic.
#2 Polish the paper
Care and attention to detail always show. Make sure you proofread the paper well. Adhere to the standards of formatting and citation. And most importantly, make sure your paper is clear, interesting, logical, and well-supported by evidence.
#3 Study examples
There are plenty of argument essay examples available on the internet. Studying these examples should help you see how tips for effective writing are reflected in well-written essays.
#4 Review writing guides
Reading multiple writing guides on how to write an argumentative essay step by step will enhance your writing skills. Such guides don’t just teach you how to start an argumentative essay; they teach you all the basics you need to write the entire paper.
#5 Get professional help
Increase your chances by enlisting the help of professionals. There are many online services that offer writing, editing, and tutoring services. Experts will take a look at your work and give you great advice.
Although getting a good grade is a nice reward for all your labor, remember that the main goal of this project is to enhance your research, writing, and critical thinking skills. Focus on the quality of your thoughts and your output, and high grades will automatically follow. | <urn:uuid:35501f57-88f2-43d6-a166-4d66d47c5a09> | CC-MAIN-2023-40 | https://121clicks.com/tutorials/how-to-write-an-argumentative-essay-easy-guide | 2023-09-26T06:13:26Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.933943 | 1,681 |
REPORT: The Cheesecake Factory Is Coming to Lubbock
According to the website, The Cheesecake Factory would take up space in the east parking lot of the South Plains Mall by building a freestanding building in front of Barnes & Noble.
The Cheesecake Factory's closest locations to Lubbock are currently in The Metroplex, Oklahoma City and Albuquerque. Locations for The Cheesecake Factory are usually located in mall complexes; sometimes, freestanding and sometimes within the mall itself.
In addition to varieties of cheesecake, deserts and salads, The Cheesecake Factory also serves steaks, burgers and other entrees.
Projected groundbreaking is scheduled for August 2018. | <urn:uuid:478259e2-b9a2-4cbf-b6c4-635baf4e926c> | CC-MAIN-2023-40 | https://1470kyyw.com/report-the-cheesecake-factory-is-coming-to-lubbock/ | 2023-09-26T06:37:08Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.940937 | 143 |
Mercedes Vito is the brightest representative of today’s distribution trucks and vans. The basis was taken as a “trolley” W638. The German company has been producing “hardworking” trucks since 1996. The new version replaced the Mercedes-Benz MB 100. The whole model range is Mercedes-Benz.
- Car history
- Release of a new car
- Mercedes-Benz Vito second generation restyling
- Еxterior second-generation
- Interior second-generation
- Shortcomings in the salon
- Second-generation powertrain
- Second-generation transmission
- Second-generation suspension
- Second-generation braking system
- Mercedes-Benz Vito is a new generation
- Third-generation powertrain
- Third-generation transmission
- Third-generation pendant
- Third-generation steering wheel
- Price and equipment
- Reviews by car owners
- The pros and cons
- Summing up
- Mercedes-Benz Vito 2014
- Test drive
- Video overview
The story begins in 1995. In those years, the company DaimlerChrysler, located in the northern part of Spain, began to produce in series a “truck” Mercedes Benz Vito, who proved to be a quality employee in the first year of use.
Interestingly, the next year, in 1996, the Mercedes-Benz Vito received the award as the best van of the year.
At the onset of 1996 in Geneva, for the first time showed a multi-purpose wagon of increased capacity from a German company, which appeared on the platform of Vito, which was called V-Class. To increase comfort, instead of pneumatic elements, twisted springs on the rear wheels were installed. In addition, they decided to improve noise insulation, interior finishing, and change the appearance of the truck with the help of hinged elements.
As a result, there was a car, containing the payload of a commercial car, but with a higher level of comfort. The model has been produced since 1997. The following year, the trucks were equipped with a lightweight restyling – began to install CDI (diesel powered), which uses a fuel system Common Rail. The quality of the vehicles was improved by means of visible modernization of the interior and internal equipment.
Release of a new car
When 2003 came, the company, instead of cardinal improvement of cars, decided to produce instead of obsolete fully fresh products – Vito and Viano. The two cars that the company decided to produce at the same time are similar in appearance, but differ in their components.
The novelty was presented in 3 versions – as a full-fledged working car, passenger and cargo compartment and a minibus. Already from the autumn coolness of 2003, the new Mercedes model began to replace little by little the low-tonnage commercial vehicles.
The Vito second family Mercedes is available in 3 body lengths – Comfort, Long and long Extralong, 2 wheelbases (3,200 and 3,430 mm), 2 roofs (low and high, with a usable volume of 4.65 to 6.49 m3 respectively). There are also 5 power units with a power range from 88 to 218 horsepower.
By the way, since 2005, the middle variant of the roof has been assembled. One of the most attractive will be the van Panel van, with a body volume of 6.49 m3, up to 1,140 kilograms of payload and a 6-seater Vito Mixto, which represents a combined passenger and cargo transportation with a trunk designed for 970 liters of usable space.
The model can accommodate up to 6 people and transport large quantities of goods, which is necessary for many industries, such as construction, utilities and so on. For those who are interested in the number of seats in the car, there will be a variant of Vito, which is designed to transport nine people, including the driver. Taking this into account, there will still be about one cubic meter of free space in the luggage compartment, where various things can be placed.
Mercedes-Benz Vito second generation restyling
The most important difference of Vito of the 2nd family is a completely new body. If before it had a angular view, now there is a place for soft and energetic lines, which is clearly visible, looking at the nose and side of the car, proportional to the line from the bumper to the windshield and a quiet transition to the side.
Details simply can not be confused – they clearly have the family features of Mercedes. The external restyling includes a replaced radiator grille and an effective stamping on the hood. The aft area of the vehicle also received the presence of rear lamps of vertical design.
Regardless of the wheelbase, the novelty comes with the latest side doors that glide smoothly. They have made it much easier to load things in the car. Rear mounted doors, which received a swing principle of operation, acquired an opening angle of 180 and 270 degrees. They are ordered in place of the rear door, which rises upwards, allowing easy loading of any material. The luggage compartment opening between the arches of the wheels is 1,277 millimetres.
If you pay attention to the opinion of experts, the Vito models, which were produced at the beginning, had a better assembly than the other cars after the update in 1988. Journalists note that after restyling, the car has received poor quality fittings of body panels.
Under the armchairs installed in front, provided a place for the location of various loads, which entails an auxiliary 200 millimeters of useful length in any wheelbase. The maximum weight allowed for transportation on the roof is 150 kg.
It’s a pity, but the 2nd generation model wasn’t immune to rust.
However, it is pleasant that V-class had painted bumpers and exterior mirrors of rear view. After restyling, the door handles were also painted to match the body painting.
Moving to the interior, it is clear that the appearance has affected the important details – the “board” of devices, keys and tools to adjust the air conditioner, pockets and modest niches for a variety of things. At the top, the dashboard received a compartment where the A4 folder was placed.
The glove compartment has grown in free space and now the volume is 11 liters. The seat on which the driver sits, along with the seat of the passenger sitting next to him, can be adjusted in the longitudinal direction. In addition, there is a soft adjustment of the seats in height, backrest inclination and seat cushions. The interior has received the presence of seats with built-in three-point safety belts.
Such moments made the interior decoration of Mercedes Vito elaborate and convenient for passenger transportation. There is a modification of Marko Polo, which has a rising roof. In addition to the latter, the salon received a refrigerator and even a gas stove.
Cargo-and-passenger modifications of the car without glazing of the aft part are called Mixto. V-class is separated from the Vito mounted even in the basic configuration of the suspension on the air, which can underestimate the aft part of the car and keep the height of the ground clearance constant.
Shortcomings in the salon
But the car has also received disadvantages, and not every modification of the upgraded vehicle deserves high praise, if we compare it with the previous family. Some complain about the lack of visibility, because the presence of a large front post, promises to obscure the view during the turn, and installed in the middle of the headrest of the rear seat, completely deprived the driver of visibility. When the sun is shining, orange icons on the “tidying” are hard to see. Therefore, to read information from the dashboard, there is nothing left to do, as with the help of a hand to cover it from the sun rays.
Speaking of the design of the Mercedes-Benz Vito W639, if we compare it with its predecessor, there is almost nothing to connect them. These are completely foreign vehicles. The first thing that distinguishes them is the layout. The previous model had a drive on the front wheels and a power plant, which was placed transversely, and the new generation got a longitudinal arrangement of the “engine” and gearbox. The drive began to go to the rear axle. It was necessary to change the drive because of two problems.
The first is that the previous machines transmitted vibrations to the steering wheel – and the rear-wheel drive system solved this problem. The second reason is passive safety. Provided that the previous generation of Vito will pass the crash-test, it will become clear that in the event of a collision, the power pack will go into the car, which is fraught with bad consequences.
When the engine has a longitudinal layout, it “goes” under the floor, which reduces the level of danger. In addition, minivans with front drive had unloaded rear wheels, which was clearly observed in the body of the van.
The new generation has got a lot of choice of engines. There were 5 engines, which met the Euro-4 standards. These are the engines, which have an ordinary four, running on diesel CDI of the 2nd family. The power varied: 88, 109 and 150 horsepower. There were also V-shaped six-cylinder engines running on gasoline, which had the function of injection Bosch Motronic ME 2.8 and produced 190 and 218 “horses”.
It’s nice that the engines in the new generation became more dynamic, more environmentally friendly and, importantly, more economical today.
The basic equipment had a 6-speed manual transmission. V-shaped gasoline “sixes” had a five-stage automatic box, which, if necessary, was installed on diesel units. Thanks to improvements in the transmission, the ride comfort was improved and the vehicle became more reliable on the road.
It is independent for four wheels. The front mechanisms are equipped with McPherson shock-absorbing columns, on which the stabilizer brackets are mounted. The rear suspension is equipped with spherical springs and shock absorbers.
Second-generation braking system
All wheels are equipped with disc brakes, which are ventilated at the front and standard at the rear. The standard equipment is able to adjust the braking forces and has a hydraulic emergency braking system Brake Assist.
Mercedes-Benz Vito is a new generation
In 2014, the German company radically changed the attitude towards the minivan and showed a new generation. Mercedes-Benz Vito W 447, the Germans presented modestly. It happened at the October Motor Show in Paris in 2014. The fresh model was launched in European countries in October of the same year.
It will be possible to buy the model on the territory of the Russian Federation not earlier than November 2014. The very first generation of Vito, which was produced since the mid-1990s, was a simple, high-quality front-drive car. The model was distinguished by a quite modest price tag and minimum ambitions.
The second family already has a rear drive, with which it was produced before the 3rd generation. But the W 447 now comes with three drives to choose from: front, rear and all-wheel drive. Since the beginning of production, more than 1,200,000 cars have been sold, which is very impressive.
The novelty, in reality, is an affordable and utilitarian variation of the beautiful new Mercedes-Benz V-Class. However, the modest Vito model with its small number of modifications, which offer different variants of power units and types of drives, can seriously compete with its “brother”.
After watching the videos and photos, where the novelty is shown, there is a lot of similar to the appearance of Mercedes-Benz B-Class. There is a place for decent and representative body shapes and lines, headlights, made in a very stylish way, solid false radiator grille, where there is a large three-ray icon.
The car has an improved aerodynamic drag coefficient – 0.32 Cx. However, on the unpainted bumpers (only the Select version in the passenger version received a bumper under the body color), swinging or lifting doors of the luggage compartment, uncomplicated light alloy rollers and even installed steel wheels with hoods, it is clearly visible that the Vito 3 family is a working “horse”. Regardless of his modesty, the W 447 looks beautiful on the construction site, in front of the company’s office, or in the city center.
The salon of the third Vito family is very comfortable, ergonomic and practical. Of course, it is not as luxurious as in the V-class, but it is still modern and functional. The driver’s seat gives the driver ultimate comfort. There are no unpleasant feelings even during long trips. Many people understand that Vito is often used for commercial purposes, so the driver can travel for long hours. The salon has received many compartments for safety of various trifles and bottles.
The luggage compartment of the “truck” and the cargo-and-passenger version of Miksto provides for the presence of guides to fix the European pallet, hooks for fixing cargo on the floor and the side of the cargo department. If you pay attention to the passenger model Vito Tourer, it can comfortably carry 8-9 passengers, including the driver. On the second and third row, if necessary, there is a possibility to fold and dismantle seats that will allow to turn the car into a considerable van.
When purchasing a 3rd generation Mercedes Benz Vito, the company provided 5 diesel engines that all meet the serious Euro-6 environmental standards. The weakest is the 1.6-liter, 88 hp turbo diesel 109 CDI. Next comes a similar engine, but with 114 horsepower (111 CDI). Next come 2.1-liter diesel engines 114 CDI with 136 horsepower and 116 CDI with 163 “horsepower”.
The Mercedes-Benz Vito 119 BlueTEC engine with a capacity of 2.1 litres is considered the top version. It develops this engine already 190 horsepower. Among the features of the new Vito can be noted increased by 20% efficiency. For example, 88 hp engine in urban mode does not ask for more than 7 liters. The most powerful engine consumes, which is very unusual, only 100 grams more. Part of the reason for this is the introduction of the start/stop system.
1.6-litre engines operate with a six-speed manual transmission. The model has a front-wheel drive configuration. The 163 hp motor is already synchronized with either the six-speed manual transmission or the optional 7G-Tronic Plus automatic transmission.
The model has a rear-wheel drive layout. The most powerful engine transmits torque to all wheels and is synchronized only with the automatic gearbox 7G-Tronic Plus.
The car’s suspension’s been fine-tuned a little bit. Although in general, this was not an urgent need. Suspension of the novelty provides comfortable travel, excellent handling and excellent driving stability. Vito 2014-2017 has a fully independent suspension system with McPherson’s forward columns and multilever system at the back.
Passenger variants of the Tourer received even as standard comfortable shock absorbers and soft springs, which are much better than those installed in the cargo version. The noise insulation of the Vito’s truck version was a bit of a displeasure.
The passenger version is slightly better, but still far from the noise insulation of Mercedes Viano. Although it is not surprising, because it is still a different class of cars.
Third-generation steering wheel
The steering wheel is very easy to control, which is achieved by using electric power steering. That’s why it’s very easy and convenient to drive.
Based on safety tests, 3rd generation Mercedes-Benz Vito is the safest car in its class. Previously, no other truck of this type was equipped with a pair of airbags and an unpleasant buzzer that makes you fasten your seatbelts. Top-end versions have not only airbags, but also side curtains in a circle.
Price and equipment
You can buy compact passenger and cargo vehicles from $32041. It will be a basic truck set with the weakest 1.6-liter diesel engine, producing 88 horsepower and synchronized with the 6-speed manual transmission. The top model will cost from $61238 for a 2.1-liter 190 hp engine with a 7-speed automatic gearbox.
The basic equipment includes systems for monitoring the physical condition of the driver and the pressure in the wheels, an on-board computer, 8 airbags, ABS, ESP, systems for monitoring blind areas and intersection of road markings, a simple audio system that supports MP3 and USB. Also it is possible to establish the advanced multimedia system where there is a colour screen supporting touch input (works with music, phone, navigating system, back visibility camera), system of stabilization at gusts of a lateral wind.
Reviews by car owners
Many drivers praise the car very much, especially the 1st generation. Explaining this is quite easy. The second generation has received a rear-wheel drive, so in winter the car gets stuck almost everywhere you can. The only exception is when the car is loaded.
Many car owners note that they are generally satisfied with the purchase, and the impressions are the most positive. Powertrain (CDI) is distinguished by good injectivity. Despite their age, many of them can easily accelerate up to 190 kilometers per hour. Of course, the height of the ground clearance of the Vito is not so high, but the cross-country ability of the model is good. Often it is difficult to warm up the car in winter, helps out Webasto. Do not forget about the air suspension Mercedes Vito, with which the level of comfort increases.
German quality is always praised, so the car can walk a long time, requiring only replacement of consumables. If you have to buy a new part, you will have to pay a little more, because the Mercedes parts cost always more than the same domestic or Chinese cars.
But if you put the part – it will serve a long time faith and truth. There are almost no problems with automatic gearbox, if you take care of it in time. In many respects everything depends on the conditions of operation and maintenance of the vehicle.
The pros and cons
- Nice and stylish appearance;
- Good cross-country ability;
- The latest generation offers a choice of 3 drive options – front, rear and full;
- Rich even base complete set;
- When buying a new car, you can buy the necessary options;
- Tested quality;
- High degree of safety;
- Fast payback;
- You can change the car for your own needs;
- Improved aerodynamic component of the minivan (3rd generation);
- Comfortable and comfortable interior;
- Ability to travel as a family;
- Comfortable steering wheel;
- Low fuel consumption;
- Pretty injected and sharp power unit;
- Good visibility;
- The 3rd generation has received the stylish colour screen supporting touch input;
- Comfortable seating for driver and front passenger.
Cons of a car
- 3rd generation cars are expensive;
- 2nd generation Vito is very difficult to use in winter because of the rear-wheel drive (poor traction with road surface when the car is empty);
- Details cost a lot of money;
- In the secondary market, most cars have traveled more than one hundred thousand kilometers;
- Compared to the same Sprinter, the height inside the Vito is quite small;
- It is not recommended to overload the car;
- In winter time it is difficult to heat up the whole salon.
In general, a lot of people like them even old Vito’s models. Most people still dream of buying a car like this. Due to the fact that the German company decided to produce the 3rd generation of the model, where you can finally choose between front, rear and all-wheel drive.
The quality of the car as a whole and the interior itself is simply impressive. The power unit is sharp enough, allows you to feel confident during overtaking and at high speeds. Quite small fuel consumption will only please car owners. Of course, there is a famous pain in the throat – rottling body, but any body needs care.
It’s nice that the company paid attention not only to the level of comfort, but also to the safety of the machine. Thus, many of them have different systems designed to help the driver to drive the vehicle. There are also airbags. Inside there is a lot of free space, passengers do not feel discomfort.
With three rows of seats, the luggage compartment is not a record-breaking one, but it allows you to take the most necessary things with you. In addition, you can use the transportation of cargo on the roof of the car. Mercedes Vito is pleased with the price. The German quality has always been famous all over the world, and it is pleasant that, despite of big enough “experience” on the road, Mercedes Vito once again proved it.
We advise you to read the article: Mercedes-Benz, classic German cars | <urn:uuid:57fa6967-eed5-4586-9378-2903bf6d8776> | CC-MAIN-2023-40 | https://1cars.org/4490-mercedes-benz-vito-specifications-equipment-photos-videos-overview.html | 2023-09-26T05:38:59Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.959536 | 4,561 |
Transportation Systems Management & Operations
TSMO Strategies Preserve Existing Transportation System
Performance-based transportation planning is a central underpinning of the FAST Act. With it comes emphasis from FHWA on integrating systems management and operations. It encourages us to look at more ways to optimize existing transportation facilities either through advanced technologies or strategies.
FHWA has developed Transportation Systems Management and Operations (TSMO), a set of strategies that focus on operational improvements that can maintain — and even restore — the performance of the existing transportation system before extra capacity is needed. The goal is to get the most performance out of the transportation facilities we already have.
The benefits to TSMO can include:
- Improved quality of life
- Smoother and more reliable traffic flow
- Improved safety
- Reduced congestion
- Less wasted fuel
- Cleaner air
- Increased economic vitality
- More efficient use of resources (facilities, funding)
New system and corridor approaches to optimizing mobility, include such things as:
- Connected and coordinated traffic signals, including adaptive signals with detection, preemption, etc.
- Traveler information systems
- Active Traffic Demand Management enabled by traditional technologies and emerging technologies including hard shoulder running, variable speed limits, V2X technologies enabled by DSRC and 5G for connected and autonomous vehicles (CAV)
- Ramp Metering
- Work Zone Management
- Traffic Incident Management
- Special Event Management
- Road Weather Management
- Transit Management
- Freight Management
- Congestion Pricing
- Integrated Corridor Management
- Access Management
- Improved Bicycle and Pedestrian Crossings
OKI recognizes the need and the opportunity that lies ahead. The region needs to do more with less, while also laying foundations for the future. This includes new infrastructure that can accommodate high-speed data transmission, such as fiber optic cable, DSRC and 5G. This is necessary for the efficient collection and dissemination of roadway and transit information, as well as information flow between vehicles and the infrastructure (V2X). This step leads to a fully connected environment that eventually leads to a fully autonomous environment. The pace of this evolution will depend on the social acceptance of such a system. Without question, technology challenges will be easier to solve than social acceptance of autonomous mobility.
Cellular V2X shows great promise for connecting vehicles to everything, including the network, other vehicles, even pedestrians. It relies on cellular communications. Source: NGMN
Applying coordinated and/or adaptive signal systems as exemplified by closed loop and centralized systems. This may also include signal priority for transit vehicles. The benefits of improved signal systems are commonly measured by reductions in travel time, vehicle stops, delay, fuel consumption, and emissions, and increases in travel speed.
Expansion of traveler information systems
Information on travel times and incidents provided in real-time to the traveler via dynamic message signs; a personal electronic device or telephone 511 system. ODOT and KYTC currently operate dynamic message signs; information through website or personal electronic device; and a 511 system for a large portion of the region’s interstate highway system. As vehicles become smarter and more connected, motorist information would not likely come from dynamic message signs but directly to your vehicle.
Active traffic management
This is an approach for dynamically managing and controlling traffic demand and available capacity of transportation facilities, based on prevailing conditions, using one or a combination of real-time and predictive operational strategies. When implemented together and alongside traditional travel demand management strategies, these operational strategies help to maximize the effectiveness and efficiency of the transportation facility; and they result in improved safety, trip reliability and throughput. Components of active traffic management may include speed harmonization, temporary shoulder use, queue warning, dynamic merge control, construction zone management, dynamic truck restrictions, dynamic rerouting and traveler information, dynamic lane markings or automated speed enforcement.
Ramp metering is an effective way to improve traffic flow on freeways. The meter allows traffic to enter the freeway at a rate dependent on the conditions of the freeway traffic. Motorists may be delayed at the meter, but freeway speeds and overall travel times are improved.
Source: Washington State DOT
OKI recommends several TSMO corridors for implementation
|control_id||County||Facility||Location||Description||Type||Cost Estimate (current $M)||Elements|
|9761||Dearborn||US 50||SR 350 Aurora to I-275||TSMO Corridor 1 (6 miles)||TSMO||$0.48||add wireless interconnect, 6 -20 signals suburban, adaptive, transit signal preemption. Includie soriginal transit sorridor cost of 5.36. plus adaptive signals|
|10008||Kenton||US 25 (Dixie Hwy)||Pike St to Ewing Blvd||TSMO Corridor 3. Create a high-frequency, enhanced bus transit corridor, with improved bus stop/station design and amenities. Length = 9.5 miles||Transit||$6.33||add wireless interconnect, 6 -20 signals suburban, adaptive, transit signal preemption. Includie soriginal transit sorridor cost of 5.36. plus adaptive signals|
|9876||Boone||KY 18||I-75 to KY 237||TSMO Corridor 4. Upgraded, adaptive interconnected signal upgrade(3 miles)||TSMO||$0.36||wireless interconnect, 6 -20 signals suburban, adaptive|
|10010||Kenton||I-71/75||Ohio River to I-275||TSMO Corridor 5 (7.0 miles)||TSMO||$11.00||fiber, DMS, minor shoulder pavement, cameras, poles, power|
|10011||Kenton||I-275||I-71/75 to Combs-Hehl Bridge||TSMO Corridor 6 (10.0 miles)||TSMO||$15.70||fiber, DMS, minor shoulder pavement, cameras, poles, power|
|10012||Campbell||I-471||I-275 to Ohio River||TSMO Corridor 7 (5.6 miles)||TSMO||$8.80||fiber, DMS, minor shoulder pavement, cameras, poles, power|
|10009||Hamilton||US 27 (Colerain Ave)||Struble Rd to Blue Rock Rd||TSMO Corridor 8 (4.6 miles)||TSMO||$0.61||Interconnected and adaptive signal upgrade 4.6 miles|
|9954||Hamilton||I-71||McMillan Ave to I-275||TSMO Corridor 9 - (14.5 miles) Smart lane||TSMO||$22.80||HSR, fiber, DMS, cameras, poles, power. (14.5 miles)|
|10090||Warren||I-71||I-275 to SR 48||TSMO Corridor 10 (11 miles)||TSMO +lane||$17.27||fiber, DMS minor shoulder pavement, cameras, poles, power|
|9955||Hamilton||I-275||US 42 to Loveland Madeira||TSMO Corridor 11||TSMO + lane||$42.00||Implement smart lane and add thru lanes from US-42 to Loveland Madeira|
|9956||Clermont||I-275||Loveland Madeira to SR-28||TSMO Corridor 12||TSMO + lane||$55.70||Implement smart lane and add thru lanes from Loveland Madeira to SR-28, including widening of bridge over Little Miami River| | <urn:uuid:fea732d3-7437-4474-99bb-602398445d34> | CC-MAIN-2023-40 | https://2050.oki.org/transportation-systems-management-operations/ | 2023-09-26T06:11:34Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.836673 | 1,601 |
Paris Saint Germain (PSG) star Kylian Mbappe continues to give Liverpool fans hope over a potential transfer for him this summer.
Earlier this week, the French World Cup winner followed some active Liverpool players on Instagram to send Liverpool fans into transfer ecstasy.
He followed the Liverpool duo of Mohamed Salah and Fabinho on the social media app.
In addition, €180m striker Mbappe also followed former Liverpool players like club legend Steven Gerrard and the Barcelona duo of Luis Suarez and Philippe Coutinho on Instagram.
In his latest interview with popular media channel ESPN, Kylian Mbappe praised Liverpool manager Jurgen Klopp who recently led the Reds to the Champions League title.
Klopp and Liverpool won the Champions League title during their final clash with North London giants Tottenham Hotspur which ended in a 2-0 win courtesy goals from Mohamed Salah (penalty) and substitute Divock Origi either side of the halftime interval.
It was their first Champions League title in 14 years since the 2005 triumph which saw Liverpool come from three goals down to beat Italian Serie A giants AC Milan on penalties after both teams had played a 3-3 draw.
When ESPN presenter Mauricio Pedroza asked him about his team on FIFA game, his answer was Liverpool.
When pressed further on his choice, he said Liverpool won the Champions League. | <urn:uuid:4539ef0a-3ff0-47b1-98bd-47a012b55343> | CC-MAIN-2023-40 | https://234sport.com/kylian-mbappe-boosts-liverpool-transfer-rumours/ | 2023-09-26T05:50:55Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.950758 | 277 |
Liverpool have gotten an injury boost with a recent report disclosing that Guinea international, Naby Keita has returned to training at Anfield.
The Reds played their second match in the Uefa Champions League tournament on Wednesday night against Napoli.
This match saw Liverpool midfielder, Naby Keita suffered a back injury in the first half of the game.
Naby Keita was immediately rushed off the pitch by medics before he was finally transferred to an Italian local hospital.
Uncertainties and fears arose over how long the top-rated midfielder will be on the sideline, however, recent report have made it known that Naby Keita has been discharged from the Italian hospital.
The report added that he is back at Anfield and Liverpool are even contemplating on whether to start him against Man City on Sunday.
According to Italian medics, the Guinea international didn’t have a cardiological problem, they hinted that it was only a strong back trauma which didn’t affect his spine.
It was also revealed that he is now in good condition and the injury was really severe as previously thought.
This is a big boost for Liverpool as he might be featured when they host Man City at Anfield on Sunday. | <urn:uuid:e26a6029-1665-451d-8644-245d1397af31> | CC-MAIN-2023-40 | https://234sport.com/liverpool-contemplating-on-starting-naby-keita-against-man-city/ | 2023-09-26T05:27:06Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.98394 | 248 |
It is almost hard to believe that at this time last year interest rates were still near zero. But with spiraling inflation threatening to totally derail the economy, the Federal Reserve has raised rates in an almost unprecedented fashion, and it is all but assured they will raise them again tomorrow. The difference this time is that after four straight 75-basis-point increases, the Fed is expected to lift the benchmark federal funds rate by only 50 basis points.
One group of stocks that generally fares well during a rising rate period is those in the value category. Value stocks are those trading at levels that are perceived to be below their intrinsic fundamentals. Characteristics of value stocks include high dividend yields and low price-to-book and low price-to-earnings metrics. In addition, value stocks typically have a bargain price, as investors see the company as unfavorable in the marketplace.
After a big fall rally, and with winter right around the corner, it makes sense now to look for value stocks with healthy dividends. With just over two weeks left in 2022, now is the time for tax-loss selling and to move those proceeds to some value winners that will be solid portfolio additions in 2023.
We screened our 24/7 Wall St. research database looking for top value ideas rated Buy across Wall Street that pay solid and dependable dividends. The following stocks hit our screens and look like top plays for 2023. It is important to remember that no single analyst report should be used as a sole basis for any buying or selling decision.
This is a top pharmaceutical stock pick across Wall Street. AbbVie Inc. (NYSE: ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories. The company develops and markets drugs in areas such as immunology, virology, renal disease, dyslipidemia and neuroscience.
One of the biggest concerns with AbbVie is what might happen eventually with anti-inflammatory therapy Humira, which has some of the largest sales for a drug ever recorded. The company was concerned, so in June of 2019 it announced that it has agreed to pay $63 billion for rival drugmaker Allergan, the latest merger in an industry in which some of the biggest companies have been willing to pay a high price to resolve questions about their future growth. The purchase officially closed in May of 2020.
The bad news for shareholders is that AbbVie may be nearing the limits of how far it can boost Humira’s price as cheaper competitors come to market, a problem Allergan is already grappling with as more alternatives to Botox emerge.
Shareholders receive a 3.63% dividend. Morgan Stanley’s $182 Wall Street high target price is well above the consensus target of $159.83. The shares ended Monday trading at $165.32 apiece.
The legacy telecommunications company has been going through a long restructuring, has lowered its dividend and has sold off or merged underperforming assets. AT&T Inc. (NYSE: T) provides telecommunications, media and technology services worldwide.
Sponsored: Find a Qualified Financial Advisor
Finding a qualified financial advisor doesn’t have to be hard. SmartAsset’s free tool matches you with up to 3 fiduciary financial advisors in your area in 5 minutes. Each advisor has been vetted by SmartAsset and is held to a fiduciary standard to act in your best interests. If you’re ready to be matched with local advisors that can help you achieve your financial goals, get started now. | <urn:uuid:1a841815-14f9-4949-9c13-f364f1bf9456> | CC-MAIN-2023-40 | https://247wallst.com/investing/2022/12/13/rates-head-higher-again-this-week-5-value-stocks-to-buy-now-come-with-big-dividends/ | 2023-09-26T06:14:52Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.963039 | 740 |
Durban Poison Strain UK
Durban Poison Strain UK is a Sativa-dominant strain with a unique, appealing aroma. It is known for its spicy, hazy taste with hints of aniseed, liquorice, lemon, and cloves. This complex aroma is one of the reasons why Durban Poison has such a large following of repeat growers.
It has gained popularity worldwide for its sweet smell and energetic, uplifting effects. Durban Poison is the perfect strain to help you stay productive through a busy day, when exploring the outdoors, or to lend a spark of creativity. Growers and concentrate enthusiasts will both enjoy the oversized resin glands which make this strain a quality choice for concentrate extraction. The buds are round and chunky, and leave a thick coating of trichomes on almost all areas of the plant. | <urn:uuid:65865545-4b5c-4f7b-9a9f-63d5e41268de> | CC-MAIN-2023-40 | https://420skunkuk.com/shop/buy-marijuana-strains-online-uk/durban-poison-strain-uk/ | 2023-09-26T05:24:42Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.93808 | 171 |
Dimensions: 89"W x 41.7"D x 31.1"H
Description: The Canni Sofa, with its elegantly curved silhouette and luxurious velvet upholstery is simply breathtaking. Boasting a curved silhouette, sumptuous velvet upholstery and a plush foam fill, this elegant sofa will elevate the look of your living space, and allow you to relax in style.
Handmade by skilled furniture craftsmen
Plush velvet upholstery
Sturdy kiln-dried pine frame with zig-zag spring support
- Available in multiple color options
Seat Width: 89"
Seat Depth: 24.8"
Seat Height: 17.7"
- Arm Height: 2" | <urn:uuid:30b5868f-4fa4-40f0-a5c8-5786b1de38ff> | CC-MAIN-2023-40 | https://6ixthsensela.com/products/canny-sofa | 2023-09-26T06:38:21Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.829161 | 167 |
Old Navy is stepping up to give back during the coronavirus pandemic. The retailer has announced plans to donate $30-million worth of clothing to families in need. They’ll be partnering with nonprofits Good360 and Baby2Baby to give away the clothes.
“To all the families out there keeping it together for Zoom school and uniting us with TikTok challenges, thank you for doing your part,” Old Navy shares in a video. “Now we’re doing ours.”
Along with the multi-million dollars of clothes they’re donating, Old Navy is also giving 50-thousand non-medical grade reusable masks to the Boys & Girls Clubs of America.
Source: ABC News | <urn:uuid:cb9569c4-98d1-4102-a6dc-f6d3584ba76d> | CC-MAIN-2023-40 | https://710wor.iheart.com/content/2020-05-14-old-navy-donates-30m-in-clothing-to-families-in-need/ | 2023-09-26T06:43:24Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.932412 | 152 |
Researchers believe the Warsaw Grouper caught off the coast of Florida is over 50 years old. In fact, it's the oldest specimen the group has ever seen in the ageing program. Agler Jason Boyll caught the mammoth fish in 600 feet of water and immediately posted to Instagram. While this catch is large, it isn't the largest. The largest known Warsaw Grouper caught was 436 pounds, 12 ounces.
Photo: Getty Images | <urn:uuid:c3cd19e2-7cb3-4bec-8c70-2228140c2172> | CC-MAIN-2023-40 | https://949thebull.iheart.com/featured/spencer-and-kristen/content/2020-01-13-florida-fisherman-catches-a-grouper-weighing-350lbs/ | 2023-09-26T05:54:35Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.967045 | 89 |
We've waited a long time for this! Luke Combs packed out Kidd Brewer Stadium at App State over the weekend and he didn't disappoint. Over 32 thousand fans showed up to see him. One thing we love about Luke is how he doesn't forget the people who helped mold him into the man he is today. During the show Luke credited his friend, Andy Stoker from Newton- Conover.... for the reason he is where he's at today. See why in the clip below. | <urn:uuid:037ebc05-1d4d-4591-9324-062ac026f22d> | CC-MAIN-2023-40 | https://969thekat.iheart.com/content/2021-09-07-luke-combs-packs-out-kidd-brewer-stadium/ | 2023-09-26T06:13:49Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.985884 | 99 |
One of the regular aspects of swimming pool maintenance that you must keep up with as a pool owner is making sure the filter pressure is at the correct levels. The filter pressure must be within an efficient range if you are to get the best results out of the system.
Your pool filter pressure gauge in New Haven County, CT tells you the pressure inside the filter tank, which is an important reading to help you determine how well your filter is operating. The pressure at which your filter system should be operating is based on the kind of filter system you have—some may run higher than others. This means there isn’t a single overarching pressure measurement you should be looking for. Instead, you need to be able to get the settings just right for the system you have.
Most of the time, systems will be either in the five to 15 psi or 10 to 20 psi range. Clean your filter thoroughly, empty the pump and skimmer baskets and start up the filter. When it reaches its full power level, you can check the pressure gauge reading, and this will give you your starting pressure. This should be the lowest pressure at which your system operates. At anywhere from five to 10 psi above that starting reading, you’ll need to clean out the filter again.
If you find your system operating at more than 10 psi outside of that normal range, then there is something wrong with the system and you’ll need to make the appropriate repairs.
Dealing with low pressure
High pressure often means you simply need to clean out the filter system. But what happens if you have low pressure?
Usually low pressure in the pool filter system in New Haven County, CT is indicative of a flow problem, often caused by something blocking the water flowing into the pool pump. Here are a few examples of some of the most common causes of low pressure that a technician will look for when analyzing your pool equipment:
- Reduced water movement inside the actual pool
- A clogged pump impeller, pump basket or skimmer basket(s)
- A filter valve that allows water to bypass the filter
- A pool cleaner failing to perform its job, likely because it’s either stopped working or simply isn’t moving around the pool well enough
- A pump that’s either not priming or leaves air in the system when not operating
- Eyeball fittings not in their correct place at pool returns
- Clogged main drain covers or skimmer pipes
- A fully or partially closed skimmer or main drain valve
- A bad, worn-out pressure gauge
Each one of these issues will have its own solutions. It might be something as simple as cleaning a part, or it may require some more significant repairs and maintenance, including potential part replacement.
But if you believe you are dealing with low pool filter pressure, it is important for you to take immediate action to resolve the problem. To combat the issue of low water pressure in your pool filter system in New Haven County, CT, contact A-1 Pools & Spas today.
Categorised in: Pool Contractors | <urn:uuid:61b20c4f-1a61-46df-bc9f-cbd84322d842> | CC-MAIN-2023-40 | https://a-1poolsandspas.com/2020/10/why-your-pool-may-have-a-low-filter-pressure/ | 2023-09-26T06:40:31Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.946941 | 635 |
What is PrestaShop?
With PrestaShop, you’ll be able to swiftly launch an online shopping portal and to maintain it effortlessly. The web application offers a new and much more user–friendly way of running an e–shop, with the key philosophy being “Things must be simple”. PrestaShop is translated into a variety of languages and right now powers more than 130 000 active e–stores.
PrestaShop’s backend offers you all the features that you may need – they are only a click away. You will be able to quickly manage an unlimited number of products, to sort them by price or by availability, to modify them, to set up bulk discounts for all goods or for just a specific number of goods and much, much more.
PrestaShop™ is a registered trademark of PrestaShop SA and shares no affiliation with NRGHost Hosting.
PrestaShop–Optimized Linux Shared Website Hosting Plans Services
At NRGHost Hosting, you will find PrestaShop Linux shared website hosting plans services. Our PrestaShop Linux shared website hosting plans packages have been created with your website in mind – each of them offers an automatic PrestaShop installation, a 99.9% uptime guarantee for your website and a free domain name registration or transfer.
We also realize how time–swallowing taking care of an online shopping portal can be. That is the reason why we offer you unlimited disk space, unlimited monthly traffic and unlimited MySQL database storage space allocations. And your web content will be secure as well – we offer regular data backups, along with automatic Dropbox backup possibilities. No need to dedicate any time to tweaking your website to fit into the Linux shared website hosting plans package’s limits – our Linux shared website hosting plans service will address your site’s needs instead.
A Point & Click Web Site Control Panel
For our PrestaShop Linux shared website hosting plans plans, we have developed a brand–new Web Site Control Panel. It’s designed to work only with NRGHost Hosting’s shared website hosting platform and this gives it a critical edge over similar Web Site Control Panels in terms of speed and security. It’s also meant to remove the need to have extra billing and domain name management panels – you can manage your web site, your domains and your billing transactions from one single location. What is more, our Web Site Control Panel is jam–packed with helpful tools and free bonuses.
We’ve got tools that will be helpful to both novices and trained users. NRGHost Hosting’s Sitemap Generator will enable you to set up a full site map for your website with merely several mouse clicks. Our Web Site Accelerators will increase the speed of your website, but require a little more work in advance. NRGHost Hosting’s Quick Website Installer can set up a brand new site for you with a custom site template in only four simple steps. Using our Site Creating Application, you can set up a new web site from scratch, without the need to possess any HTML, CSS or PHP abilities, but you’ll need to build each single page manually. And this is just a small list of what you can accomplish with NRGHost Hosting’s Control Panel. | <urn:uuid:447379fb-1add-48e3-8965-8a1c817f2516> | CC-MAIN-2023-40 | https://a2hosting.ru/linux-shared-website-hosting-plans/web-apps/prestashop/ | 2023-09-26T05:10:11Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.909576 | 689 |
Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection
AAPS Open volume 4, Article number: 6 (2018)
Therapies based on monoclonal antibodies (mAbs) have delivered an impressive success in the clinics due to their exquisite specificity, potential for agonistic or antagonistic responses, tunable effector function, and optimal pharmacokinetic properties. Building on these inherent antibody properties, the design and development of antibody-drug conjugates (ADCs) with improved or gained therapeutic activity and safety has been successfully demonstrated in oncological applications. There is enormous potential for this new type of hybrid biologics but there are also significant engineering, manufacturing and bioanalytical challenges. In this manuscript, we highlight the range and diversity of assays that are critical to characterize the individual components of ADCs-linker, carrier, and payload. We discuss a series of in vitro and in vivo preclinical experimental approaches we implemented to characterize two anti-inflammatory steroid bearing ADCs, and an ADC bearing a modified glucagon-like peptide 1 receptor/glucagon receptor co-agonist peptide.
Antibodies and antibody-based molecules constitute one of the most efficacious classes of therapeutic products in the biotechnology industry. Due to their generally long half-life and specificity encoded in discrete complementary determining regions, it was originally believed that, in addition to an excellent therapeutic window, the pharmacokinetic properties of recombinant antibodies will be both similar and predictable. However, it is now well understood that many factors, depending on the specific antibody and intended target, may significantly affect the drug pharmacokinetic behavior (Tabrizi et al., 2006).
Antibody-drug conjugates represent a new kind of therapeutic agents which are gaining importance especially in the oncology field (Sievers and Senter, 2013). They are the product of covalently linking a monoclonal antibody with a small molecule or peptide drug (payload). Typically, the mAb will enable a targeted delivery of the payload to a defined cell population of choice. The increase in total mass of ADC compared to payload alone improves the payload exposure due to diminished renal uptake and clearance of ADC. In addition, ADCs are expected to retain binding to the neonatal Fc receptor (FcRn), which is responsible for salvaging both immunoglobulin G (IgG) and albumin from cellular catabolism in a pH-dependent recycling and transcytosis mechanism (Andersen and Sandlie, 2009; Roopenian and Akilesh, 2007).
For ADCs with a targeted intracellular payload, the challenge is to successfully design ADCs with a balanced chemical linker strong enough to be stable in blood while efficiently cleaved once inside the cell lysosomal compartment to release its active payload. These properties would reduce systemic pharmacological exposure and non-specific effects associated with the free drug. Alternatively, for extracellular targets the mAb portion can serve as a carrier to extend the half-life of the payload from minutes to days and systemic exposure by several folds compared to when dosed as a small molecule drug. In this scenario it is critical that the stability of the linker and payload in the circulation are engineered to match appropriately the expected increase in exposure and half-life of the immunoconjugate. This is of particular importance for peptide payloads as they are more likely to be targeted by enzymatic catabolism in the systemic circulation.
Generally, conjugation of the drug to the antibody has been achieved through lysine or existing cysteine residues resulting in heterogeneous conjugations (Casi and Neri, 2012). However, there is a tremendous interest and research to produce more homogeneous ADCs through site specific conjugations using either engineered cysteine residues (Junutula et al., 2010) or through the site-specific incorporation of non-natural amino acids with unique reactive groups while minimizing antibody scaffold modifications (Axup et al., 2012; Kern et al., 2016b; Tian et al., 2014; Zimmerman et al., 2014). Regardless of the methods used for generating ADCs, a thorough characterization of the effects that the conjugated products and procedures may have on the functional properties of the antibody moiety itself is critical for lead selection and development; including binding properties, affinity and specificity, Fc effector function, off-target disposition, aggregation and novel protein interactions. In addition, because of their multi-component nature (mAb, linker and payload), these hybrid entities are more complex than a “simple” mAb or separate payload. For any given combination of mAb, linker, payload, site, type of conjugation, and the achieved drug-antibody ratio (DAR), the resulting products will consist of a mixture of ADC variants with different physico-chemical properties. This in turn, depending on the resulting heterogeneity, may affect its stability, pharmacokinetics and disposition, adversely changing the overall ADC safety and efficacy profile. Therefore, each experimental conjugate requires the development of a combination of various analytical procedures for a thorough physico-chemical monitoring, from antibody and payload conjugation, immunoassay, and cell based procedures to standard and innovative fit-for-purpose LC-MS methods. There are excellent reviews that cover several aspects of this process(Perez et al., 2014). Descriptions of bioanalytical techniques have been recently published (Gorovits et al., 2013; Kaur et al., 2013; Wakankar et al., 2011). In this manuscript, we describe several specific experimental examples of different site-specific conjugated ADC case-studies in order to highlight the complexity and range of bioanalytical methods required to characterize their properties in vitro and their pharmacokinetic and disposition behavior in vivo (Outlined in Fig. 1). Two cases presented here are: 1) Anti-inflammatory steroid-ADCs directed to specific cell surface receptors (CD25 and CD74) for targeted internalization; 2) A modified Glucagon-like Peptide 1 receptor/Glucagon receptor (GLP1R/GCGR) co-agonist-bearing ADC (Pep-ADC) designed for improved systemic exposure and prolonged pharmacological activity via peptide cell surface receptor binding and activation.
All animal procedures described here were performed in accordance with the established guidelines and regulations by our Institutional Animal Care and Use Committee (IACUC). Animals were housed and maintained in facilities under a protocol approved by and in accordance with the guidelines of the American Association for Assessment and Accreditation of Laboratory Animal Care.
Monoclonal antibodies and ADC compounds
Monoclonal rat-mouse chimeric anti- mouse IL-2Rα (CD25) IgG1 was coupled to dexamethasone (Dex) with either a novel proprietary phosphate based linker (anti-CD25-Phos-Dex) (Kern et al., 2016a) or with a cathepsin based linker (anti-CD25-Cat-Dex) (Kern et al., 2016b), as described in the respective references. These ADCs were generated in partnership with Ambrx Inc. (La Jolla, CA). Humanized anti-human CD74 IgG1 either unconjugated (unconjugated anti-CD74) or conjugated to budesonide using phosphate linker (anti-CD74-Phos-Bud), humanized anti-human CD74 IgG4 (anti-CD74–011), human anti-viral IgG4 (mAb3), and mAb3 conjugated to modified Glucagon-like Peptide 1 receptor/Glucagon receptor (GLP1R/GCGR) co-agonist peptide (Pep-ADC), were all generated in partnership with Ambrx. Mouse anti-Dexamethasone IgG1 (MEB113.53F3.104A) and mouse anti-Dexamethasone IgG2a (MEB113.8D1.7F) were generated at Merck & Co., Inc. (MRL, Palo Alto, CA).
In vitro stability of anti-CD25-Phos-Dex and anti- CD25-Cat-Dex
Anti -CD25-Phos-Dex or anti-CD25-Cat-Dex (15 μg/150 μL plasma) was spiked in normal male DBA1 mouse plasma for up to 18 days at 37 °C. After incubation, samples at selected time points were analyzed by total antibody immunoassay (Total IA), measuring anti-CD25 antibody still capable of binding the target regardless of the presence or absence of payload, and ADC specific immunoassay (ADC IA) using Mesoscale Discovery (MSD) sandwich immunoassay (Meso Scale Discovery, Rockville, MD), and free dexamethasone was determined by LC-MS (Free Dex). For Total IA, the plasma samples spiked with each ADC were added to MSD MA6000 96-Small Spot plate coated with recombinant mouse IL-2 Rα (R&D System, Minneapolis, MN) as a capture molecule. After incubation and washes, wells were incubated in goat anti-rat IgG (Fc), F (ab’)2-Biotin (Sigma-Aldrich, St. Louis, MO). Finally for detection, SULTO-TAG labeled Streptavidin was added to the wells, signal was read on the MESO SECTOR S 600 reader after adding MSD read Buffer T. For Anti-CD25 conjugate ADC specific immunoassay, similar procedure was followed, however, mouse anti-dexamethasone IgG2a (MEB113.8D1.7F)–Biotin (Merck) was used to detect dexamethasone containing intact ADC in spiked plasma.
For LC-MS detection of Dexamethasone, plasma protein was precipitated by addition of 400 μL of internal standard solution, consisting of 20 ng/mL of Dexamethasone-d4 (TLC PharmaChem, Vaughan, ON) in acetonitrile to 40 μL of plasma. Samples were vortexed for 30 s and centrifuged at 14,000 rpm for 10 min at 4 °C. Supernatants were transferred to a clean tube and dried in Centrivap vacuum concentrator (Labconco, Kansas City, MO). Samples were reconstituted with 40 μL of 50% methanol /aqueous solution and 5 μL was injected into the ESI(−)LC-MS/MS (Acquity Waters, Milford, MA; TSQ Vantagem, ThermoScientific, Waltham MA). Analysis was performed on a Ascentis Express C18 (50 mm x3mm × 2.7 μm) (Sigma-Aldrich) column with a 3 min linear gradient from 50 to 95% Buffer B (Buffer A: 0.1% formic acid aqueous solution; Buffer B: 0.1% formic acid in acetonitrile) at 0.4 mL/min. Dexamethasone and dexamethasone-d4 were detected using the transitions 437.0 > 361.3, and 441.0 > 363.3, respectively. Method showed linearity from 0.1 ng/mL to 2000 ng/mL.
In vivo stability of anti-CD74-Phos-Bud in human CD74 transgenic mice
Human CD74 expressing transgenic (Tg) mice (B6.Cg-Tg(CD74)AR194Ayr/j) were generated and characterized previously (Honey et al., 2004). These Tg mice (n = 2/group) were dosed intravenously (IV) with either 3, 10 or 30 mg/kg of anti-CD74-Phos-Bud and plasma samples were collected at designated time points. Samples were subjected to MSD immunoassays. For total anti-CD74 immunoassay (Total IA), measuring anti-CD74 antibody still capable of binding the target regardless of the presence or absence of payload, recombinant human CD74 (R&D System) was plated on MSD MA6000 96-Small Spot plate as a target capture and mouse anti-human IgG-SULTO-TAG (SouthernBiotech, Birmingham, AL) was used as detection reagent. For anti-CD74–Phos-Bud ADC specific immunoassay (ADC IA), mouse anti-dexamethasone IgG1 (MEB113.53F3.104A)–Biotin (Merck) was coated on to MSD Streptavidin multi-array 96-well plate, and MEB113.53F3.104A-SULFO-TAG was used as the detection reagent.
Anti-CD74-Phos-Bud interacting protein in C57BL/6 J mouse plasma
Anti-CD74-Phos-Bud was immune-purified from spiked C57BL/6 J mouse plasma using NanoLink Streptavidin Magnetic beads (Solulink, San Diego, CA) immobilized with biotin-SP-conjugated AffiniPure F(ab’)2 fragment goat anti-human IgG (H + L) (Jackson ImmunoResearch) with 3 h incubation at 4 °C. After capture, beads were separated from plasma using a magnetic rack and washed five times with 0.1% RapiGest (Waters) in TBS 1× solution. Samples were eluted with 30 μL of 0.25% formic acid solution and neutralized by the addition of TRIS HCl (1 M). Samples were heated for 3 min at 80 °C for denaturation, reduced with DDT (final concentration of 5 mM) for 30 min at 60 °C, and alkylated with iodoacetamide (final concentration of 15 mM) for 30 min at room temperature in dark. Digestion was performed by addition of 2.5 μg of trypsin (Promega, Madison, WI) to each sample, and incubation for 4 h at 37 °C. Digestion was quenched by addition of HCl (final concentration of 200 mM) and samples were further incubated at 37 °C for 45 min for hydrolysis of remaining RapiGest. Samples were centrifuged at 14,000 rpm for 10 min at 4 °C, and 4 μL of digests were injected in a LC-MS/MS system NanoAcquity (Waters)/ LTQ-Orbritrap XL (ThermoScientific) with a 60 min linear gradient from 5 to 56% Buffer B (Buffer A: 0.1% formic acid aqueous solution; Buffer B: 0.1% formic acid in acetonitrile) at 0.4 μL/min. Search was performed using the Proteome Discoverer Software (ThermoScientific).
DyLight™ 650 labeling of antibodies
DyLight™ 650 labeling kits (ThermoScientific) were used to conjugate an N-hydroxysuccinimide ester fluorescence dye (excitation at 652 nm and emission at 672 nm) to anti-CD74, anti-CD74-Phos-Bud, and isotype matched control antibody (mAb-C), Pep-ADC, and mAb3, using the method described in previous publication from our group (Brunn et al., 2016).
In vitro stability assessment of DyLight 650 labeled anti-CD74, anti-CD74-Phos-Bud, and isotype control antibody (mAb-C) by SEC-HPLC
For assessing stability in mouse plasma in vitro, DyLight 650 labeled anti-CD74, anti-CD74-Phos-Bud and isotype matched control antibody (mAb-C) were incubated at 37 °C in C57BL/6 J mouse plasma (100 μL) at a final concentration of 80 μg/mL, samples were taken out and snap frozen at designated time points, and stored at − 80 °C until analysis. For SEC-HPLC analysis, 25 μL of plasma samples from time points were applied onto a BioSep-SEC-S3000 column (Phenomenex, Torrance, CA) at 1 mL/min elution rate with PBS as a mobile phase for 15 min, and analyzed using an Agilent 1200 HPLC system (Agilent Technologies, Santa Clara, CA). The effluent was monitored continuously at 280 nm and by the net fluorescence intensity at an excitation wavelength of 646 nm and emission of 674 nm, as described previously (Brunn et al., 2016).
Biodistribution of DyLight 650 labeled anti-CD74-Phos-Bud and unconjugated anti-CD74–011 mAb in mice
Transgenic human CD74 mice (B6.Cg-Tg(CD74)AR194Ayr/j) and normal wild type C57BL/6 J female littermates (WT) (n = 2/group/time point) were given 5 mg/kg IV bolus of DyLight 650 labeled-anti-CD74-Phos-Bud. A separate group of wild type littermates (n = 2/time point) were administered with 5 mg/kg of DyLight 650 labeled-anti-CD74–011. Animals were euthanized with carbon dioxide followed by terminal cardiac puncture. Blood, plasma, and selected tissues were harvested to measure drug concentration. Whole blood samples were collected into K2-EDTA CapiJect microcollection tubes (Terumo Medical Corporation, Somerset, NJ) and placed on ice. For drug analysis in whole blood, samples were aliquoted into polypropylene vials (Corning Glassworks, Corning, NY) and stored at − 80 °C. Plasma was separated from whole blood via centrifugation for 6 min at 6000×g at 4 °C, and stored at − 80 °C. For tissue lysates, organ samples were collected and immediately placed into 2-ml Precellys Lysing Tubes (Bertin Technologies, Rockville, MD), weighed, and frozen by placing on dry ice. To prepare lysates, upon partial thawing, a 1:5 dilution of Dulbecco’s PBS containing 1% Triton X-100 (MP Biomedicals, Solon, OH) and 1× Halt Protease Inhibitor single use cocktail (ThermoFisher Scientific) was added to the samples. Then, tissue slurries were prepared using a Precellys Evolution Homogenizer (Bertin Technologies). The slurry was centrifuged (10,000×g at 4 °C for 10 min) and the tissue lysate supernatants were collected and either processed immediately or stored at − 80 °C until analysis.
Determination of DyLight 650 labeled -anti-CD74-Phos-Bud and anti-CD74–011 mAb concentration in tissue samples by fluorescence emission–linked analysis (FELA)
For assessment of tissue drug concentration, the collected blood, plasma, and tissue lysate samples or a set of corressponding blank tissue samples were diluted 1:10 (final dilution) with tissue lysis buffer (1× DPBS with 1% Triton X-100). The diluted samples (150 μL) were transferred to 96-well polystyrene plates with low fluorescence background for analysis in the Glomax® Multi-Detection system microplate reader (Promega). The microplate reader was equipped with a fluorescence optical filter featuring excitation and emission wavelengths of 625 nm and 660 to 720 nm, respectively.
For each DyLight 650 labeled antibody, fluorescence intensity calibration curves were established by serially diluting spiked blood and liver lysate. A linear correlation function was fitted to the data using best-fit parameters on Microsoft Excel. The resulting blood calibration curve equation was used to fit unknown blood and spleen lysate samples, and the liver calibration curve equation was used to fit unknown liver lysate samples. Concentrations of DyLight-650 labeled antibodies were calculated as microgram equivalents per gram of wet tissue or as microgram equivalents per mL of blood. Subsequently, tissues to blood ratios were calculated by dividing concentration in respective tissue by concentration in blood at the designated time point.
Assessment of bioactive and total Pep-ADC in mice
In order to measure the bioactivity of Pep-ADC in plasma (Bioassay), plasma samples from C57BL/6 J male mice with diet induced obesity (DIO) dosed with 10 mg/kg IV bolus of Pep-ADC were incubated with GLP1R transfected Chinese hamster ovarian (CHO) cells for 1 h. The reactions were stopped by adding cell-lysis buffer from cAMP CISBIO kit (Cisbio, Bedford, MA). A calibration curve was established using different amount of Pep-ADC spiked into plasma to stimulate GLP1R-CHO cells and quantify cAMP release in a 96-well corning white plate using cAMP CISBIO kit. Bioactivity of Pep-ADC was back-calculated and reported as μg/mL.
To determine the total antibody level (Total mAb3 assay), MSD immunoassay was used. Plasma samples from Pep-ADC dosed animals were applied to Streptavidin Gold Multi-Array 96-well Plate (MSD) coated with mouse anti-Human IgG4-Biotin (SouthernBiotech) as a capture reagent, and SULFO-TAG-mouse anti-Human IgG (Southern Biotech) was used for detection.
Pep-ADC intact mass analysis by AP-LC-MS
Mouse study: C57BL/6 J male mice (n = 3) with diet induced obesity were dosed with 3 mg/kg IV bolus of Pep-ADC. Plasma samples collected at day 1, 3, 7, and 10 were processed for intact mass analysis.
Non-human primates study: Treatment naïve male rhesus monkeys (n = 3) weighing 6–7.1 kg were fasted overnight and dosed with 3 mg/kg IV bolus of Pep-ADC. Plasma samples collected at 5 min, day 1, day 3, day 7, day 10, and day 14 were processed for intact mass analysis.
Pep-ADC was retrieved from plasma samples from both studies by affinity purification for LC-MS as follows. Nanolink Streptavidin Magnetic beads (Solulink) were preloaded with biotinylated polyclonal goat anti human IgG (SouthernBiotech). Preloaded magnetic beads (20 μl) at 2.5 mg/ml in TBS pH 7.4, 0.02% Rapigest SF Surfactant (Waters) was added to 30 μl of K2-EDTA plasma sample. Captured Pep-ADC was eluted in 30 μl of 0.25% formic acid (FA), reduced with 5 mM TCEP for 30 min at 60 °C, and 10 μl was injected into Waters Acquity UPLC I class on line with Waters Synapt G2S QTOF mass-spectrometer. Reverse phase chromatography was used on the Poros R2/10 column (2.1 × 30 mm) (Applied Biosystems, Waltham, MA) with flow rate 0.1 ml/min, 7 min gradient 30% to 58% B, 65 °C. Buffer A was water, 0.1% FA, buffer B was 90% Acetonitrile, 0.1% FA. Mass Spectrometry conditions were: capillary voltage of 3.2 kV, cone voltage of 80 V, desolvation temperature 450 °C. Mass data was acquired in m/z mass range of 500–4000. The mass spectrum was deconvoluted and integrated using MassLynx software (Waters).
Pep-ADC quantitative mass spectrometry based assay (LC-MRM)
50 μL of solulink magnetic beads were coated by rotation with 250 μL of goat anti-human IgG (monkey absorbed)-Biotin (SouthernBiotech) for 30 min at room temperature. The beads were washed 3 times with TBS/0.02% RapiGest and resuspended in 50 μL of TBS/0.02% RapiGest. For affinity enrichment, 5 μL of bead was incubated with 30 μL of plasma and TBS/0.02% RapiGest up to 50 μl for 30 min on a rotator. The beads were washed 3 times with TBS/0.02% RapiGest and once with TBS (pH 7.4), eluted with 30 μL of 0.1% formic acid, and neutralized with 2.5 μL of 1 M ammonium bicarbonate.
50 mM TCEP was added for reduction and the mixture incubated for 30 min at 60 °C. Digestion was done with 0.25 μg of trypsin for 5 h at 37 °C. 1 pmol of labeled peptides spanning residue 1 to 12 (representing intact molecule) and residue 24 to 30 (representing M1) was added as internal standard. 5 μL was injected into an Acquity TSQ Vantage for multiple reactions monitoring of R1-R12 and R24–30 peptides.
Biodisposition of Pep-ADC in mice
Normal C57BL/6 J mice (n = 2/group/time point) were administered a single 3 mg/kg IV dose of either DyLight 650 labeled Pep-ADC or unconjugated mAb3. Plasma and tissue samples were collected at 1 h, day 1, 2, 3, 5, 7, 9, and day 14 post dose.
To generate plasma concentration vs time profiles, DyLight 650 labeled drug concentration in plasma was determined by FELA as described previously for anti-CD74 studies.
To determine in vivo stability of DyLight 650 labeled Pep-ADC and unconjugated mAb3 by SEC-HPLC, undiluted plasma samples collected at 1 h, day 2, 5, 9 and day 14 from each group were applied onto a BioSep-SEC-S3000 column (Phenomenex) at 1 mL/min elution rate with PBS as a mobile phase for 15 min, and analyzed using an Agilent 1200 HPLC system (Agilent Technologies). The effluent was monitored continuously at 280 nm and by the net fluorescence intensity at an excitation wavelength of 646 nm and emission of 674 nm, as described previously (Brunn et al., 2016).
To determine cellular disposition of the labeled antibodies, 1 h and day 1 post dose pancreas sections cut from formalin fixed paraffin embedded (FFPE) tissue blocks were deparaffinized and rehydrated with serial passage through changes of xylene and graded ethanols for DyLight 650 immunohistochemistry (IHC). All slides were subjected to heat induced epitope retrieval in TRS solution (pH 6.1) (Dako, Carpineteria, CA). Endogenous peroxidase in tissues was blocked by incubation of slides in 3% hydrogen peroxide solution prior to incubation with primary antibody, FITC-conjugated anti-DyLight 650 clone 12A3 (Merck) for 60 min. Antigen-antibody binding was visualized via application of rabbit anti-FITC antibody (Invitrogen, Carlsbad, CA) then Envision Rabbit HRP (Dako) and application of 3, 3′ diaminobenzidine (DAB) chromogen (Dako). Stained slides were counterstained with hematoxylin and coverslipped for review.
All pharmacokinetic parameters were estimated or calculated by non-compartmental analysis (NCA) using Phoenix® WinNonlin® software (Certara, Princeton, NJ). Model 201 (IV input bolus) was used for the NCA.
Case-study 1: Anti-inflammatory steroid-ADCs
Systemic anti-inflammatory drugs are often used in the treatment of chronic conditions such as inflammatory bowel disease (Baumgart and Sandborn, 2007) and asthma (Lipworth, 1999). As a class, steroids are largely not cell or tissue specific and their systemic use is dose-limited due to harmful side effects (Brunton, 2011). Developing a targeted delivery of the most potent immune system repressors through an antibody-drug conjugate could provide a more effective dose and dosing rational for enhanced efficacy without triggering nonspecific detrimental side effects (Kern et al., 2016a).
Through site specific conjugation in the CH1 domain (Axup et al., 2012), we coupled potent anti-inflammatory molecules, dexamethasone and budesonide, to different monoclonal antibodies aimed at surface receptors broadly expressed on immune cells involved in inflammation. In this modality, the ADC should remain intact in the systemic circulation, bind to its intended target on the surface of immune cells followed by target-mediated internalization and drug release in the lysosomal compartment. The active drug is then released to engage glucocorticoid receptors inside the cell. In addition to their affinity and specificity, it is expected that these antibody conjugates should retain ideal pharmacokinetic properties mainly affected by target-mediated clearance and display a pattern of organ disposition similar to normal endogenous IgGs.
Anti-CD25 mAb conjugated to dexamethasone with cathepsin or phosphate linker: Importance of linker stability
A monoclonal antibody against CD25 or Interleukin − 2 receptor alpha chain (IL-2Rα), expressed in a subset of immune cells (Triplett et al., 2012), was coupled to dexamethasone (Dex) using either a novel proprietary phosphate based linker (anti-CD25-Phos-Dex) (Kern et al., 2016a) or a cathepsin based linker (anti-CD25-Cat-Dex) (Kern et al., 2016b). In order to fully characterize the ADC stability in mouse plasma, several assays were developed. Initially these included: A total antibody immunoassay measuring anti-CD25 antibody still capable of binding the target regardless of presence or absence of payload (target-capture and anti-Fc detection); A conjugate specific ADC immunoassay (target capture and anti-Dex detection); And a LC-MS assay to measure free Dex.
Mouse neat plasma spiked with anti-CD25-Phos-Dex was incubated over the course of 18 days at 37 °C. The total antibody and ADC specific immunoassays showed a constant concentration across all time points (Fig. 2a). Likewise, the LC-MS assay for free Dex showed no appearance of unconjugated payload at any time-point consistent with the intactness of this construct in plasma.
In contrast, the same ADC but with the cathepsin linker (anti-CD25-Cat-Dex conjugate) showed a very different stability-time profile. Total antibody levels were unchanged and no free Dex was detected (Fig. 2b). However, the ADC proved to be highly unstable as illustrated by a dramatic decrease in concentration over time measured by the ADC-specific immunoassay (Fig. 2b). To investigate the unexpected lack of stability of anti-CD25-Cat-Dex in plasma, we developed a method based on affinity purification followed by intact mass measurement by LC-MS (AP-LC-MS). Anti-CD25-Cat-Dex spiked in plasma was retrieved using antigen-bound beads and its mass was measured on a Q-TOF mass spectrometer Synapt G2S. The analysis was consistent with a clipping site in the linker moiety at a C-O bond, between the linker and the drug moieties, which was not the part of the predicted cathepsin cleavage site (Fig. 2c). Linker cleavage at this novel site explains the decrease in intact ADC in the immunoassay and the absence of free drug by LC-MS as the drug remains attached to a part of the broken linker. The same clipping was also observed when anti-CD25-Cat-Dex was incubated in phosphate buffered saline (PBS). Regardless of other approaches, the implementation of an AP-LC-MS intact mass method should become an essential tool to monitor the integrity of the ADCs.
Contrary to the cathepsin sensitive linker ADC (anti-CD25-Cat-Dex) instability, the AP-LC-MS intact mass analysis of anti-CD25-Phos-Dex showed no evidence of drug release or linker instability resulting in a constant drug to antibody ratio with molecular weights comparable to the stock solution at all-time points (unpublished observations). This result was consistent with ADC-specific immunoassay results (Fig. 2a).
The potential relevance of in vitro ADC analysis depends largely on their translatability to appropriate preclinical models for safety and efficacy. These in turn should be selected based on their relevance to the human physiology and expected mechanism of action (MoA) of the ADC and free drug. Therefore, the stability of anti-CD25-Phos-Dex was further tested in a preclinical PK study. Mice were administered a single intravenous injection of 4 mg/kg of anti-CD25-Phos-Dex. Both immunoassays (total and ADC) showed overlapping concentrations with a typical IgG PK profile (unpublished observations). Likewise, the total mass spectrum for the ADC showed an identical profile to the stock solution and unchanged drug to antibody ratio of 2 at all time points. These results are consistent with the overall good stability of the anti-CD25-Phos-Dex including the drug, linker, and antibody components both in vitro and in vivo.
Anti-CD74 mAb conjugated to budesonide with phosphate linker: Importance of the targeting antibody properties
In a different ADC construct with a monoclonal antibody targeting CD74, a cell surface receptor which is known to associate with MHC class II molecule (Borghese and Clanchy, 2011), a more potent anti-inflammatory steroid, budesonide (Bud), was conjugated using an identical phosphate linker at the same amino acid residue position in the CH1 domain. The systemic stability of the resulting ADC (anti-CD74-Phos-Bud) was characterized following IV dosing in mice at 3, 10, and 30 mg/kg. The plasma levels of total mAb versus conjugate-specific immunoassay results showed an apparent linker and/or payload instability (Fig. 3), contrary to the first example of anti-CD25-Phos-Dex. However, the AP-LC-MS analysis indicated a constant peak, identical to the original dosing material demonstrating the intactness of the ADC construct up to 6 h, after which strong peak broadening was observed and the total ion chromatograms could not be deconvoluted, suggesting heterogeneity. This could be due to severe conjugate modifications, aggregation, or protein interactions. In addition, no free Bud could be detected by LC-MS at any time point. Therefore, additional studies were implemented to better understand these discrepancies. Anti-CD74-Phos-Bud was incubated in mouse plasma for 14 days at 37 °C and retrieved by pull-down for tryptic digestion and analysis by LC-MS for identification of ADC associated plasma proteins. Analysis of these samples and a control sample with no ADC spiked in the original mouse plasma revealed the presence of several unexpected, off-target ADC-associated proteins (Fig. 4). These included: alpha-2 macroglobulin, ceruloplasmin, complement C3, albumin, fibrinogen beta, and murinoglobulin 1. Using a different approach, anti-CD74-Phos-Bud and unconjugated (naked) anti-CD74 were labeled using a DyLight-650 fluorescent dye to follow their size exclusion chromatography (SEC) profile over time upon incubation in mouse plasma at 37 °C. Samples were analyzed on an Agilent 1100 high pressure liquid chromatography (HPLC) system equipped with an in-line fluorescent detector. The resulting chromatographic profiles (Fig. 5a and b) indicated antibody instability as shown by the formation of high molecular weight (HMW) complexes for both constructs. By day 14 of incubation, only 53% of anti-CD74-Phos-Bud and 60% of drug unconjugated anti-CD74 antibody remained as a single intact monomeric IgG peak. A control antibody (Fig. 5c) remained at 96% in the same conditions. The immunoassay discrepancies between total anti-CD74 versus intact ADC values may be attributed to assay interferences due to antibody aggregation or off-target association with plasma proteins preventing payload detection. The identification of anti-CD74-Phos-Bud HMW complex formation in plasma was consistent with the off-target interactions identified by LC-MS, and pointed to a potential flaw in the properties of the anti-CD74 mAb moiety but not in the linker or the payload or the conjugation process.
Unconjugated anti-CD74 mAb shows off-target clearance mechanism in mice without CD74 target
Clearance of free IgGs and small, non-precipitating IgG complexes happen primarily by interactions with Fc receptors (FcRs) and non-specific protein clearance via fluid-phase endocytosis (Nash et al., 2001; Rojas et al., 2005; Takai, 2002). These pathways are expected to drive the elimination of anti-CD74 in species without the target expression or binding. To determine the PK properties of this anti-CD74 antibody, wild C57BL/6 J mice were administered a single intravenous dose of unconjugated anti-CD74. As show in Table 1, non-linear PK properties were observed for this antibody (Table 1).
AUC0-INF: Area under the curve from zero to infinity; CL: Clearance; Cmax: Observed maximum concentration; t1/2: Terminal half-life; Vss: Volume of distribution at steady state
Frequently, non-linear PK of mAbs may be explained by target mediated disposition (TMD). TMD is a saturable process and it is characterized by decreasing clearance with increasing doses. On the contrary, clearance of unconjugated anti-CD74 appeared to be higher when higher doses were administered. In addition, since this anti-CD74 antibody does not recognize the murine target receptor, its PK was not expected to reflect TMD. Here, observed increases in clearance at higher doses are consistent with the presence of a low affinity, high capacity off-target antibody sink (i.e., a non-specific clearance mechanism). This is, in general, an undesirable property for a targeting antibody that is characterized for its specificity and extended systemic half-life.
Anti-CD74-Phos-Bud tissue disposition pattern in mice with and without human CD74 target confirms off target effect with anti-CD74 mAb
To gain a better understanding of the DMPK properties of Anti-CD74-Phos-Bud, and the relevance of target versus off-target interactions in the fate of anti-CD74-Phos-Bud in vivo, we utilized a transgenic (Tg) mouse strain that expresses the human CD74 receptor (Honey et al., 2004). The expression of this human receptor is driven by the endogenous analog murine promoter; therefore, these transgenic mice display abundant receptor expression in spleen and to a lesser degree in hepatic tissues. Since anti-CD74-Phos-Bud does not recognize murine CD74, wild type (WT) littermates were used to evaluate the effect of target versus off-target interactions in the distribution and elimination of this antibody-drug-conjugate. In addition, a different, unconjugated anti-CD74 monoclonal antibody (referred to as anti-CD74–011 mAb hereafter) was used as a control for background tissue uptake characteristic of a non-specific IgG clearance mechanism, with known negative organ accumulation and tissue to blood ratios below 1. Mice were given an IV dose of 5 mg/kg of DyLight-650-labeled anti-CD74-Phos-Bud and anti-CD74–011 mAb. Figure 6 shows the μg-equivalents/gram (μg/g) of wet tissue or μg/ml of blood in Tg and WT mice. In concordance with the organ receptor expression levels, anti-CD74-Phos-Bud distributed extensively to the spleen and liver in the Tg mice with peak concentrations of 87 μg/g at 2 h in spleen and 43.5 μg/g at 6 h in liver. However, disposition to spleen and liver in the wild type littermates was also unusually high (34.1 and 33.7 μg/g) six hours post IV dosing. In contrast, the spleen and liver drug levels in the anti-CD74–011 mAb clone group using wild type littermates were below 11 μg/g at all time points in both organs. Accordingly, anti-CD74-Phos-Bud tissue to blood ratios were as high as 99 for the spleen at day 1 and 66.9 for liver at day 2 in Tg mice (Fig. 7a). However, tissue to blood ratios higher than 1 were also found in spleen and liver from wild type littermates consistent with off-target interactions. Overall these results demonstrated the presence of an antibody driven, off-target mechanism of tissue uptake and disposition, and were consistent with the identification of non-specific protein interactions in the circulation and undesirable PK for this construct. Based on these results, this anti-CD74 mAb was therefore not further considered as a lead therapeutic candidate. In this case, the intrinsic unfavorable properties of the antibody alone determined the overall poor fate of this ADC in vivo. This conclusion was further supported by observations with the anti-CD74–011 mAb, which demonstrated excellent stability in biomatrices. In a follow up disposition study, anti-CD74–011 mAb exhibited higher tissue to blood ratios in spleen compared to liver in human CD74 expressing transgenic mice at any evaluated time points, with ratio in spleen reaching as high as 224 at day 2 compared to 48.7 in liver (Fig. 7b). Furthermore, tissue-to-blood ratios in wild type mice for both tissues were lower than 0.5 at any evaluated time point (Fig. 7b). These observations were consistent with anti-CD74–011 mAb target-mediated uptake following administration to the transgenic mouse strain that expresses the human form of CD74 (Fig. 7b).
Case-study 2: GLP1R/GCGR peptide-ADC (Pep-ADC): Importance of payload stability
Due to their precise specificity, peptide drugs are gaining importance as therapeutic agents. However, their small size, rapid clearance rates, and systemic catabolism have limited their clinical potential and applications (McGregor, 2008; Sato et al., 2006). The use of balanced Glucagon -like peptide 1 receptor/Glucagon receptor (GLP1R/GCGR) co-agonist has shown enhanced efficacy and safety relative to pure GLP1R agonists in the treatment of rodent obesity, with simultaneous improvement in glycemic control (Day et al., 2012; Day et al., 2009; Pocai et al., 2009).
Using site specific conjugation, we coupled a modified-for-stability GLP1R/GCGR co-agonist peptide (payload) to a residue in the CDR H1 of a non-targeting human mAb (mAb3) via a non-cleavable linker. The linked peptide-mAb3 immunoconjugate is referred to as Pep-ADC hereafter. In this modality, it is expected that the antibody moiety will provide a stable carrier for prolonged exposure in the circulation of the linked peptide due to reduced renal clearance and engagement of the FcRn recycle mechanism. In turn, this should result in a substantial improvement in the biological outcome compared to the co-agonist peptide dosed alone (Kompella and Lee, 1991). In order for this to occur, it is essential that both the linker and the bioactive peptide are designed with the required stability to match the enhanced pharmacokinetic properties conferred by the antibody conjugation. For measurements of total versus intact ADC concentrations, an immunoassay (Fc capture and Fc detection) and a cell based bioactivity (peptide-induced receptor activation) procedures were implemented.
Immunoassay, cell based bioactivity, and mass spectrometric characterization helped to determine the pep-ADC stability issue in mice
To characterize the metabolic fate of Pep-ADC in vivo, Pep-ADC was administered to mice at 1 and 10 mg/kg as a single intravenous injection. Plasma was collected over time and analyzed for both total ADC (mAb3 levels) and cell-based bioactivity (assessment of free and/or conjugated active peptide). Previous in vitro work with the free peptide (Pep) had demonstrated that only the intact moiety retained receptor binding and signaling in this cell-based assay. Pharmacokinetic results (Table 2 and Fig. 8) demonstrated more than 2-fold differences in exposure and clearance between total mAb3 and bioactive measurements in a cell based assay. Therefore, the smaller exposure and increased clearance for the bioactive ADC compared to the total ADC -suggested a potential linker instability and/or peptide catabolism.
To further understand the molecular nature of Pep-ADC potency loss, we conducted an AP-LC-MS analysis. In agreement with the bioactivity assay data, the results showed that while the intact conjugated Pep-ADC decreased with time and eventually became undetectable by day 5, several clipped variants (M1, M2, M3 and M4) representing degradation of the conjugated peptide at various positions became the predominant ADC species (Fig. 9a and b). A control group of mice dosed with the mAb3 only, without the conjugated linker-peptide, showed a constant peak (intact mAb) at the same molecular weight at all tested time points (unpublished observations) indicating no catabolism of the antibody moiety itself. Mass difference calculations identified that the conjugated peptide clipping between residues 2/3 (M4), 25/26 (M1), 27/28 (M2) and 30/31 (M3) of the peptide sequence (Fig. 9c). All clipped M-variants are inactive in bioassay, as it is known that the removal of the first two amino acids of Glucagon-like peptide-1 (GLP-1) by dipeptidyl peptidase 4 (DPP4) kills the activity of GLP-1 through GLP-1 receptor (GLP1R) (Knudsen and Pridal, 1996). This is also true for Pep-ADC, which is a modified Glucagon-like Peptide 1 receptor/Glucagon receptor (GLP1R/GCGR) co-agonist-bearing ADC. Finally, a mass spec-based quantitative assay was developed to measure the disappearance of the intact form and appearance of the main peptide catabolite (Fig. 10a). It confirmed that intact Pep-ADC disappeared fast and by day 2, only about 10% of intact Pep-ADC remained (Fig. 10b). Conversely, M1 increased for the first two days and then declined over the remaining 5 days as it was cleared and/or transformed into M2 and M3 (Fig. 10b). Overall, these data were consistent with the bioactivity assay and intact mAb measurements, and confirmed M1 as one of the most abundant metabolites in the circulation. These results indicated a path forward in the rational design of improved ADC versions focused on strengthening the stability of the peptide moiety. It is important to note that although bioactive drug exposure can be further increased with potentially more stable peptide properties in the circulation, the current exposure to active drug in this ADC was considerably better than those of similar peptides when dosed alone with half-lives ranging in the order of minutes and elimination rates closer to glomerular filtration rates (Galaske et al., 1979). For free peptides in the circulation at pharmacological doses, two powerful mechanisms drive the fast elimination of these molecules mainly by renal clearance followed by systemic enzymatic degradation (Rabkin and Dahl, 1993). Peptide clearance by target mediated uptake and cellular internalization plays a more modest role (McMartin, 1992).
Pep-ADC stability issue was also observed in non-human primates
To determine whether the Pep-ADC metabolic profile observed in mice was translatable to higher order species, rhesus monkeys were administered intravenously with a single dose of Pep-ADC at 3 mg/kg. Plasma was collected at 5 min, day 1, day 3, day 7, day 10, and day 14. Intact mass analysis by AP-LC-MS showed that the intact Pep-ADC was undetectable by day 7 (Fig. 11), similar to what had been observed in mice by day 2. Furthermore, M1 and M2 were the most abundant metabolites as early as day 3 with M1 almost completely converted to M2 by day 7. All three individual animals exhibited similar degradation profile of the Pep-ADC.
Pep-ADC exhibited normal biodisposition pattern in mice
To complete the characterization of Pep-ADC in vivo and the potential role of the conjugation and the target in the tissue distribution and catabolism of this ADC, fluorophore labeled Pep-ADC and unconjugated mAb3 were intravenously administered to normal C57BL/6 J mice at 3 mg/kg. Selected organs including plasma and whole blood were collected for up to 14 days after IV administration. The concentration versus time values (based on measurements of fluorescent tag on the antibody moiety) for the Pep-ADC and unconjugated mAb3 were similar, suggesting minimal effects of both the conjugation and the presence of the target in vivo at this dose (Fig. 12). The lack of noticeable gross organ uptake of both compounds was supported by the results of the tissue to blood ratios analysis, with values below 0.6 for all the organs tested over the course of the study (unpublished observations). Selected plasma samples were further characterized by SEC-HPLC. As expected, the total amount of the main monomeric peak representing intact IgG decreased with time due to antibody clearance (Fig. 13). However, SEC-HPLC profile showed that both conjugated and unconjugated constructs were stable in the circulation during this time with no evidence of formation of HMW complexes, aggregates, or major catabolic species. More than 90% of the labeled test materials remained as a single intact IgG peak by day 14 (Fig. 13). Importantly, immunohistochemical analysis clearly demonstrated that Pep-ADC but not unconjugated mAb3 efficiently localized to pancreatic Islets of Langerhans consistent with receptor mediated Pep-ADC uptake via specific peptide/receptor binding interactions (Fig. 14).
ADCs or armed antibodies represent one of the next logical steps in the implementation of smarter, more efficient targeted drugs. Specific delivery of highly bioactive compounds to intracellular targets via antibody-receptor binding and internalization holds promise for the arrival of novel hybrid biologics with improved therapeutic windows. There are currently 2 ADCs approved in the USA (Garnock-Jones, 2013; Lambert and Chari, 2014) for oncological applications and more than 40 ADCs currently in various stages of clinical trials (Polakis, 2016; Sievers and Senter, 2013). It is recognized that there are additional challenges and complexities associated with the design and manufacturing of bio-conjugates versus standard antibodies or small molecules production. The CMC development that made possible the production of heterogeneous ADCs for successful clinical applications marks a cornerstone in biotechnology applications (Beck and Reichert, 2014). Furthermore, as improvements in the technology or novel approaches become available, we can expect additional ADCs with better overall pharmacological properties and safer profiles. The right balance needs to be engineered in the ADC so that the linker and drug are stable in blood but are promptly sorted via antibody binding and internalization to the lysosomal compartment for efficient drug release directed towards intracellular targets.
In a different modality, ADCs can also be used to exploit the excellent pharmacokinetic properties of antibodies to extend the exposure and half-life of conjugated bioactive compounds (small molecules, ligands, or peptides). It has been our experience that in general, ADME information collected from one ADC is not directly translatable to another immunoconjugate even when using the same drug-linker combination in a different antibody and against the same target. It has also been shown that even in the same ADC construct, change in drug to antibody ratios or drug load is sufficient to dramatically change the pharmacokinetic properties of the resulting conjugates (Kamath and Iyer, 2015,; Lyon et al., 2015). This is more evident when the new ADC is directed to a different target. In non-oncological applications, the need for early ADME characterization of each lead ADC-candidate is a critical step in molecule selection and rational drug design. For this purpose, the following issues need to be addressed properly: 1) Is the linker stable? 2) Is the drug stable? 3) And is the entire ADC stable? The several approaches to address these questions are also discussed in an industry white paper (Kraynov et al., 2016).
In this paper, we have shown several experimental examples of two different ADC modalities (targeted internalization vs. half-life extension) and the corresponding complexities of the bioanalytical and preclinical ADME work necessary to properly characterize these entities both in vitro and in vivo. An early understanding of the critical physico-chemical components responsible for non-favorable or unexpected PK and ADME properties of experimental conjugates provides critical experimental feedback for a rational design, optimization, and selection of successful lead candidates.
(Dulbecco’s) Phosphate buffered saline
- ADC (s):
Antibody-drug conjugate (s)
Affinity purified LC-MS
- AUC0–14 :
Area under the curve from zero to 14 days
- AUC0-INF :
Area under the curve from zero to infinity
Cyclic adenosine monophosphate
Cathepsin based linker
Heavy chain constant domain 1
Chinese hamster ovary
- Cmax :
Observed maximum concentration
Drug to antibody ratio
Diet induced obesity
Neonatal Fc receptor
Fluorescence emission-linked analysis
Formalin fixed paraffin embedded
Glucagon-like peptide 1 receptor
High molecular weight
Institutional animal care and use committee
Interleukin-2 receptor alpha
Liquid chromatography-mass spectrometry
- mAb (s):
Monoclonal antibody (−ies)
Major histocompatibility complex
GLP1R/GCGR co-agonist bearing antibody drug conjugate
Phosphate based linker
Size exclusion-high pressure liquid chromatography
- t1/2 :
Terminal half life
Tris buffered saline
Target mediated disposition
Volume of distribution at steady state
Andersen JT, Sandlie I (2009) The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics. Drug metab pharmacokinet 24(4):318–332
Axup JY, Bajjuri KM, Ritland M, Hutchins BM, Kim CH, Kazane SA, Halder R, Forsyth JS, Santidrian AF, Stafin K, Lu Y, Tran H, Seller AJ, Biroc SL, Szydlik A, Pinkstaff JK, Tian F, Sinha SC, Felding-Habermann B, Smider VV, Schultz PG (2012) Synthesis of site-specific antibody-drug conjugates using unnatural amino acids. Proc Natl Acad Sci U S A 109(40):16101–16106
Baumgart DC, Sandborn WJ (2007) Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet (London, England) 369(9573):1641–1657
Beck A, Reichert JM (2014) Antibody-drug conjugates: present and future. mAbs 6(1):15–17
Borghese F, Clanchy FI (2011) CD74: an emerging opportunity as a therapeutic target in cancer and autoimmune disease. Expert Opin Ther Targets 15(3):237–251
Brunn ND, Mauze S, Gu D, Wiswell D, Ueda R, Hodges D, Beebe AM, Zhang S, Escandon E (2016) The role of anti-drug antibodies in the pharmacokinetics, disposition, target engagement, and efficacy of a GITR agonist monoclonal antibody in mice. J Pharmacol Exp Ther 356(3):574–586
Brunton LL (2011) Goodman & Gilman's the pharmacological basis of therapeutics. McGraw-Hill Education, New York
Casi G, Neri D (2012) Antibody-drug conjugates: basic concepts, examples and future perspectives. J Control Release 161(2):422–428
Day JW, Gelfanov V, Smiley D, Carrington PE, Eiermann G, Chicchi G, Erion MD, Gidda J, Thornberry NA, Tschop MH, Marsh DJ, SinhaRoy R, DiMarchi R, Pocai A (2012) Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents. Biopolymers 98(5):443–450
Day JW, Ottaway N, Patterson JT, Gelfanov V, Smiley D, Gidda J, Findeisen H, Bruemmer D, Drucker DJ, Chaudhary N, Holland J, Hembree J, Abplanalp W, Grant E, Ruehl J, Wilson H, Kirchner H, Lockie SH, Hofmann S, Woods SC, Nogueiras R, Pfluger PT, Perez-Tilve D, DiMarchi R, Tschop MH (2009) A new glucagon and GLP-1 co-agonist eliminates obesity in rodents. Nat Chem Biol 5(10):749–757
Galaske RG, Van Liew JB, Feld LG (1979) Filtration and reabsorption of endogenous low-molecular-weight protein in the rat kidney. Kidney Int 16(3):394–403
Garnock-Jones KP (2013) Brentuximab vedotin: a review of its use in patients with hodgkin lymphoma and systemic anaplastic large cell lymphoma following previous treatment failure. Drugs 73(4):371–381
Gorovits B, Alley SC, Bilic S, Booth B, Kaur S, Oldfield P, Purushothama S, Rao C, Shord S, Siguenza P (2013) Bioanalysis of antibody-drug conjugates: American Association of Pharmaceutical Scientists antibody-drug conjugate working group position paper. Bioanalysis 5(9):997–1006
Honey K, Forbush K, Jensen PE, Rudensky AY (2004) Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M. J Immunol 172(7):4142–4150
Junutula JR, Flagella KM, Graham RA, Parsons KL, Ha E, Raab H, Bhakta S, Nguyen T, Dugger DL, Li G, Mai E, Lewis Phillips GD, Hiraragi H, Fuji RN, Tibbitts J, Vandlen R, Spencer SD, Scheller RH, Polakis P, Sliwkowski MX (2010) Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer. Clin Cancer Res 16(19):4769–4778
Kamath AV, Iyer S (2015) Preclinical pharmacokinetic considerations for the development of antibody drug conjugates. Pharm Res 32(11):3470–3479
Kaur S, Xu K, Saad OM, Dere RC, Carrasco-Triguero M (2013) Bioanalytical assay strategies for the development of antibody-drug conjugate biotherapeutics. Bioanalysis 5(2):201–226
Kern JC, Cancilla M, Dooney D, Kwasnjuk K, Zhang R, Beaumont M, Figueroa I, Hsieh S, Liang L, Tomazela D, Zhang J, Brandish PE, Palmieri A, Stivers P, Cheng M, Feng G, Geda P, Shah S, Beck A, Bresson D, Firdos J, Gately D, Knudsen N, Manibusan A, Schultz PG, Sun Y, Garbaccio RM (2016a) Discovery of pyrophosphate Diesters as tunable, soluble, and bioorthogonal linkers for site-specific antibody-drug conjugates. J Am Chem Soc 138(4):1430–1445
Kern JC, Dooney D, Zhang R, Liang L, Brandish PE, Cheng M, Feng G, Beck A, Bresson D, Firdos J, Gately D, Knudsen N, Manibusan A, Sun Y, Garbaccio RM (2016b) Novel phosphate modified Cathepsin B linkers: improving aqueous solubility and enhancing payload scope of ADCs. Bioconjug Chem 27(9):2081–2088
Knudsen LB, Pridal L (1996) Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor. Eur J Pharmacol 318(2–3):429–435
Kompella UB, Lee VHL (1991) Pharmacokinetics of peptide and protein drugs, in Peptide and Protein Drug Delivery (Lee VHL ed) Marcel Dekker, Inc., New York, pp 391–486
Kraynov E, Kamath AV, Walles M, Tarcsa E, Deslandes A, Iyer RA, Datta-Mannan A, Sriraman P, Bairlein M, Yang JJ, Barfield M, Xiao G, Escandon E, Wang W, Rock DA, Chemuturi NV, Moore DJ (2016) Current approaches for absorption, distribution, metabolism, and excretion characterization of antibody-drug conjugates: an industry white paper. Drug metab dispos 44(5):617–623
Lambert JM, Chari RV (2014) Ado-trastuzumab Emtansine (T-DM1): an antibody-drug conjugate (ADC) for HER2-positive breast cancer. J Med Chem 57(16):6949–6964
Lipworth BJ (1999) Fortnightly review: modern drug treatment of chronic asthma. BMJ 318(7180):380–384
Lyon RP, Bovee TD, Doronina SO, Burke PJ, Hunter JH, Neff-LaFord HD, Jonas M, Anderson ME, Setter JR, Senter PD (2015) Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index. Nat Biotechnol 33(7):733–735
McGregor DP (2008) Discovering and improving novel peptide therapeutics. Curr Opin Pharmacol 8(5):616–619
McMartin C (1992) Pharmacokinetics of Peptides and Proteins: Opportunities and Challenges. In: Testa B (ed) Advances in Drug Research, pp 41–107
Nash JT, Taylor PR, Botto M, Norsworthy PJ, Davies KA, Walport MJ (2001) Immune complex processing in C1q-deficient mice. Clin Exp Immunol 123(2):196–202
Perez HL, Cardarelli PM, Deshpande S, Gangwar S, Schroeder GM, Vite GD, Borzilleri RM (2014) Antibody-drug conjugates: current status and future directions. Drug Discov Today 19(7):869–881
Pocai A, Carrington PE, Adams JR, Wright M, Eiermann G, Zhu L, Du X, Petrov A, Lassman ME, Jiang G, Liu F, Miller C, Tota LM, Zhou G, Zhang X, Sountis MM, Santoprete A, Capito E, Chicchi GG, Thornberry N, Bianchi E, Pessi A, Marsh DJ, SinhaRoy R (2009) Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice. Diabetes 58(10):2258–2266
Polakis P (2016) Antibody drug conjugates for Cancer therapy. Pharmacol Rev 68(1):3–19
Rabkin R, Dahl DC (1993) Renal uptake and disposal of proteins and peptides, in Biological Barriers to Protein Delivery (Audus KL and Raub TJ eds) . Pharm Biotechnol vol 4. Springer, Boston, pp 299–338.
Rojas JR, Taylor RP, Cunningham MR, Rutkoski TJ, Vennarini J, Jang H, Graham MA, Geboes K, Rousselle SD, Wagner CL (2005) Formation, distribution, and elimination of infliximab and anti-infliximab immune complexes in cynomolgus monkeys. J Pharmacol Exp Ther 313(2):578–585
Roopenian DC, Akilesh S (2007) FcRn: the neonatal fc receptor comes of age. Nature reviews 7(9):715–725
Sato AK, Viswanathan M, Kent RB, Wood CR (2006) Therapeutic peptides: technological advances driving peptides into development. Curr Opin Biotechnol 17(6):638–642
Sievers EL, Senter PD (2013) Antibody-drug conjugates in cancer therapy. Annu Rev Med 64:15–29
Tabrizi MA, Tseng CM, Roskos LK (2006) Elimination mechanisms of therapeutic monoclonal antibodies. Drug Discov Today 11(1–2):81–88
Takai T (2002) Roles of fc receptors in autoimmunity. Nature reviews 2(8):580–592
Tian F, Lu Y, Manibusan A, Sellers A, Tran H, Sun Y, Phuong T, Barnett R, Hehli B, Song F, DeGuzman MJ, Ensari S, Pinkstaff JK, Sullivan LM, Biroc SL, Cho H, Schultz PG, DiJoseph J, Dougher M, Ma D, Dushin R, Leal M, Tchistiakova L, Feyfant E, Gerber HP, Sapra P (2014) A general approach to site-specific antibody drug conjugates. Proc Natl Acad Sci U S A 111(5):1766–1771
Triplett TA, Curti BD, Bonafede PR, Miller WL, Walker EB, Weinberg AD (2012) Defining a functionally distinct subset of human memory CD4+ T cells that are CD25POS and FOXP3NEG. Eur J Immunol 42(7):1893–1905
Wakankar A, Chen Y, Gokarn Y, Jacobson FS (2011) Analytical methods for physicochemical characterization of antibody drug conjugates. mAbs 3(2):161–172
Zimmerman ES, Heibeck TH, Gill A, Li X, Murray CJ, Madlansacay MR, Tran C, Uter NT, Yin G, Rivers PJ, Yam AY, Wang WD, Steiner AR, Bajad SU, Penta K, Yang W, Hallam TJ, Thanos CD, Sato AK (2014) Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem 25(2):351–361
The authors acknowledge the contributions of Dr. Laurence Fayadat-Dilman at the Department of Protein Sciences; Dr. Wolfgang Seghezzi at the Department of Bioanalytics; Phillip E. Brandish and Paul E. Carrington at the Biology-Discovery Department; Robert M. Garbaccio at the Chemistry-Discovery Department; And Ambrx, Inc.
This work was supported by Merck Research Laboratories (MRL), Merck & Co. Inc.
Availability of data and materials
The datasets supporting the conclusions of this article are included within the article.
All authors are current or former employees of Merck & Co., Inc. or Ambrx, Inc. The authors declare no competing financial interest.
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
About this article
Cite this article
Beaumont, M., Tomazela, D., Hodges, D. et al. Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection. AAPS Open 4, 6 (2018). https://doi.org/10.1186/s41120-018-0026-0
- Antibody-drug conjugates | <urn:uuid:1c34d080-8a79-4c0a-93da-0eeefcbf9bfe> | CC-MAIN-2023-40 | https://aapsopen.springeropen.com/articles/10.1186/s41120-018-0026-0 | 2023-09-26T07:02:25Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.89138 | 15,643 |
The Zeroes and Ones of it All
Draw sophisticated diagrams with your keyboard
Back End meet Front End.
Variation & Consistency, according to goals.
Engineering with mixed signals.
On health, productivity, cyber security, money, & happiness
Less, but better.
A neuroscientist’s book on organization.
A summary of a summary of some great techniques.
A portable shorthand for text styling.
Making the incredibly complicated quite simple.
What is the 80/20 rule and why is it important?
The basics, cause that’s enough.
The basis of measurement, which is the basis of science.
Where things can be measured.
No matter how you slice it, all of math is fancy counting.
How to get from M/S to MPH & back again.
A review of one of the top most worthwhile books I’ve ever read.
A simple physical notetaking technique & architecture. | <urn:uuid:3e8fa6e9-164e-454d-b7f8-de7e7fb76905> | CC-MAIN-2023-40 | https://aarongilly.com/gillespedia/ | 2023-09-26T05:24:05Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.877779 | 207 |
Nobility and subtlety in a laconic interior arrangement
The first impression created by the interior design of this house is characterized by nobility. Pastel hues are accompanied by luxurious details that subtly complete each other. The floor is covered with contrasting ceramic tiles, which give the interior the feeling of power and accuracy being balanced by the calm colours of the walls. The golden accents are that touch of elegance of the interior, which is meant to become the leitmotiv of the entire house and dissolve the simplicity of the premises. They also created a harmonious geometry of the premises.
The ground floor is bright, the kitchen area, dining room and living room have been combined in a large open space. Several paintings, classic frames and the fireplace are harmoniously combined with the luminaires that also serve as decorative elements. Ceramic tiles with effect of marble have been integrated as accents on the walls both in this premise and in the study for to support the idea of durability and power of the premises.
Upstairs we have created a more private atmosphere. We opted for parquet flooring, carpets and upholstered furniture. In the bedrooms we used neutral hues, each of them being accentuated by some small chromatic details. The large windows offer plenty of natural light and due to it the comfort to the rooms.
Size: 370 m2
Location: Chisinau, Republic of Moldova
Brands: Flos, Minotti, MADLAB, Poliform, Daytona, Rex ceramica, Castro Light, Vitra, Orac Fecor
Team: Alexandrin Buraga, Marco Ballerini, Alina Bodișteanu, Gabriela Nacu
Concept: AB + Partners | <urn:uuid:f1c4b48e-893f-459f-9ffc-c2abfa5764b1> | CC-MAIN-2023-40 | https://abandpartners.net/portfolio/nobility-subtlety-laconic-interior-arrangement/ | 2023-09-26T05:25:48Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.943661 | 361 |
It is not a secret for anyone that Toro Center is one of the most important projects for us. Because it was full of challenges, but also because it is a modern touch in the urban context, it generously offered us precious experiences. After about 5 years of following how our vision emerges from structures, engineering networks and finishes, now we are seeing our creation almost finished. While you enjoy new images taken during the finishing process, we will tell you something about the project.
Architectural and urban planning concept
We designed Toro Center in harmony with the context as it is located in an important area of the city of Chisinau. We aimed to rehabilitate the area through a project with a new vision. The project creates communication links between the place and the city, establishes a connection between the local and the urban context and becomes an urban core in the generation of opportunities. Through the prism of the user, we created the opportunity to experience this space differently, through a more comfortable formula.
Toro Center complex itself unites 10 blocks with different functions. Here we are not talking about residential buildings that have reserved the ground floor as commercial space. In the case of our project, in addition to 7 residential blocks, there is a mall and an office block. Restaurants, SPA, fitness room, shops, offices, pharmacies and even a park on the terrace – all are concentrated in the commercial area of the complex. While being designed, Toro Center was the first complex that involved the intersection of several spaces: commercial, residential, exhibition, recreational and office.
It is part of the company’s philosophy and it is the thing that guarantees that Toro Center will remain up-to-date for a long time. The complex is designed in such a way that over time, there is the possibility of reconfiguring the spaces and changing their destination. Thus, the project gained the ability to adapt to the city, regardless of the context that has been formed. | <urn:uuid:4ba4d7b5-5f80-4e8d-a76a-dddb24ed3292> | CC-MAIN-2023-40 | https://abandpartners.net/portfolio/toro-center-multifunctional-hybrid-complex/ | 2023-09-26T06:03:02Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.965745 | 407 |
A review of 'Havana syndrome" by the U.S. intelligence community finds it "very unlikely" that a foreign adversary or energy weapon is the cause, officials said Wednesday.
That's according to a new assessment from the Office of the Director of National Intelligence (ODNI) released on Wednesday.
Instead, Director of National Intelligence Avril Haines said in a statement that the events, which are referred to officially as Anomalous Health Incidents, were probably the result of other factors such as "preexisting conditions, conventional illnesses, and environmental factors."
Haines added that the evidence also did not indicate that a "causal mechanism," such as a weapon, or a "unique syndrome" brought on the reported symptoms.
The report from ODNI added that confidence in the explanation was "bolstered by fact we identified medical, environmental and social factors that plausibly can explain many AHIs reported by U.S. officials," but that the level of confidence varied across agencies.
The ODNI also released a heavily redacted memo detailing the scope of the wide-ranging probe, revealing that investigators "developed and deployed multiple sensors and detection devices" in order to "analyze potential signals of interest," reviewed content on the Dark Web for leads, conducted hundreds of interviews with U.S. government officers, and even launched a "full investigation into a third-country" to "determine validity of potential reported knowledge of Russian involvement in AHI."
An intelligence official familiar with the assessment said no stone was left unturned, and that even Unidentified Aerial Phenomena were examined as possible causes.
They also said the inquiry found no singular explanation for the reported symptoms, but added that while no evidence was found to support a foreign adversary being behind any single case, acknowledged it's conceivable that a handful of instances could be the cause of a bad actor trying to inflict harm on American personnel and more research would be needed to rule out the possibility.
"Needless to say, these findings do not call into question the very real experiences and symptoms that our colleagues and their family members have reported," Haines said. "We are sincerely grateful to those who came forward, as it helped to not only shape our response, but identify areas where we need to improve our medical and counterintelligence protocols, which remains an ongoing process."
In a statement of his own, CIA director William Burns noted the assessment was the product of "more than two years of rigorous, painstaking collection, investigative work, and analysis" and "one of the largest and most intensive" in the agency's history.
But there are still many unanswered questions, and not everyone is pleased with what they called the limited information declassified to support the conclusion.
Mark Zaid, an attorney whose firm represents dozens of AHI victims, said in a statement to ABC News that the assessment "lacks transparency," adding, "we continue to question the accuracy of the alleged findings."
"Until the shrouds of secrecy are lifted and the analysis that led to today's assertions are available and subject to proper challenge, the alleged conclusions are substantively worthless," he said. "But the damage it has caused to the morale of the victims, particularly by deflecting from the government's failure to evaluate all the evidence, is real and must be condemned."
ABC’s Karen Travers asked White House press secretary Karine Jean-Pierre whether the president was satisfied with the intelligence assessment, but she did not provide a direct answer.
"What's important to the president is that we take this very seriously, as the intelligence community has,” Jean-Pierre responded." What we are committed to is making sure that our workforce and their families get the assistance that they need through the medical care. And look, the work is ongoing."
While this assessment is the result of the extensive known effort conducted by the government to identify the cause of strange symptoms that have plagued hundreds of diplomats, intelligence officers, and other U.S. personnel serving abroad, previous inquires have come to similar conclusions.
A comprehensive review conducted by the CIA and released in January found it was unlikely that a foreign power was behind most of the incidents, but a later interagency report found that some of the cases were likely brought on by directed energy or acoustic devices, suggesting they were the result of deliberate attacks.
"Havana syndrome" was first reported in late 2016 by State Department personnel stationed in the Cuban capital, but soon, diplomats and other government workers stationed around the world began experiencing similar, unexplained neurological symptoms. Over 1,500 cases have now been documented across 96 countries.
Symptoms are said to vary in type and severity, but often are reported to include the sudden onset of severe headaches, difficulty concentrating, auditory disturbances, and memory loss.
The initial incidents led to increased strain on the already fraught ties between the U.S. and Cuba, and eventually the American embassy closed its doors.
Earlier this year, the State Department said it was reopening processing for all immigrant visa categories at the U.S. Embassy in Cuba and increasing its staffing numbers, even though Havana Syndrome was still a poorly understood threat.
“The fact that we have been able to augment our staffing posture at our embassy in Havana is a signal that we are confident in our ability to mitigate the risks, confident in our ability to take prudent steps to protect our people. But this is something we evaluate and reevaluate on a virtually a daily basis,” department spokesperson Ned Price said at the time. “Diplomacy is never a risk-free endeavor.”
In September 2022, the State Department announced it had started approving payments for victims of the anomalous health incidents in accordance with the HAVANA Act -- the unanimously passed bill that authorizes agencies to compensate “personnel who incur brain injuries from hostilities while on assignment.”
While plans vary across the federal government, the State Department said in June 2022 that it would provide eligible victims a one-time, non-taxable, lump sum of between $140,475 and $187,300. The total would depend on whether the requestor had reemployment potential, if they required a full-time caregiver for activities of daily living, and other factors.
To qualify, a document published by the State Department says applicants must have sustained “an acute injury to the brain such as, but not limited to, a concussion, penetrating injury, or as the consequence of an event that leads to permanent alterations in brain function,” a medical diagnosis of a traumatic brain injury, or the acute onset of new persistent, disabling neurologic symptoms.
The injury also must have occurred on or after Jan. 1, 2016, and it must have happened while the impacted person or the victim’s direct family member was working for the department.
“Because of the varied symptoms and still-nascent understanding of how to test or otherwise screen for AHI impacts, the Department sought to establish a standard that it believes will be broadly inclusive of the types of injuries that have been reported by covered individuals to date,” the document states.
State Department spokesperson Ned Price said on Wednesday that while the department's intelligence fed into the latest assessment's conclusion, the "book is never fully closed" on investigating the cause of the malady.
"We are going to -- as a government -- going to continue to look at every single input and source of information that is available to us," he said. "An assessment like this is an assessment based on the best information available to us at any particular time."
Price also said that cases have "declined fairly precipitously" since 2021 and fewer cases have been reported so far this year than at the same point in 2022.
The top Democrat and Republican on the Senate Intelligence Committee said Wednesday that recent intelligence community findings should not affect the treatment and medical care that those affected have been receiving.
"I think the most important interest we have in the short term is assuring this report doesn't lead to people being denied care because they are accused of being partisan hysteria or something," Intelligence Committee Vice Chairman Marco Rubio said. "It's one of those things I think will continue to receive attention because there are people who were severely harmed by it."
"I think it is important and frankly the most important thing is we are taking care of the workforce for any health care issues that have arisen," Intelligence Committee Chairman Mark Warner said. "I can't speak for all members of the community in terms of the workforce, but we've got to make sure regardless of source, if people have healthcare issues they've got to get taken care of."
ABC News' Cindy Smith and Allison Pecorin contributed to this report. | <urn:uuid:95c57006-e430-4ef7-9576-c546ecc90455> | CC-MAIN-2023-40 | https://abcnews.go.com/Politics/havana-syndrome-caused-foreign-adversary-us-intel/story?id=97549657 | 2023-09-26T05:47:28Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.976465 | 1,791 |
Management of the National Service Scheme (NSS) has announced an increase in the monthly allowance for personnel of the Scheme.
A statement issued by the Corporate Affairs Directorate of the Scheme disclosed that government has given clearance for the allowance to be increased from GH¢559.04 to GH¢715.57 effective January 2023.
The NSS allowance was last adjusted in January 2017 from GH¢350.00 to GH¢559 04.
The statement assured that “all National Service Personnel who are currently in active service are entitled to arrears for the difference in the upward adjustment from January, 2023, and would be paid accordingly.”
Below is the Scheme’s statement. | <urn:uuid:0101174f-34b3-4581-8c0c-edc73c69fa0e> | CC-MAIN-2023-40 | https://abcnewsgh.com/govt-increases-nss-allowance-from-gh%C2%A2559-04-to-gh%C2%A2715-57/ | 2023-09-26T05:40:41Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.966615 | 143 |
A worrying video that has stirred massive angry reactions online captures the moment a middle-aged man dodged into a hotel room with a girl who doesn’t look a day above 12.
As seen in the video, the middle-aged man was followed by his young girlfriend who’s probably still in Junior High School.
Shockingly, he was given an easy pass to lodge into the hotel room without any interrogation.
Social media users who have come across the video have called on authorities to immediately arrest the man and also penalize the management of the hotel.
Reacting to the video,
@Wizarab10 for instance commented – She doesn’t look a day above 12. We no longer have communal responsibility. Nobody wants other people cautioning their kids, so this is what you get.
@therealdaddymo1 also angrily commented – This is what we mean by an enabling environment for sexual predators, rape and statutory rape. She looks underage. Plus the predator, plus the receptionist, plus the hotel management, plus the person recording, plus those who saw them entering the hotel and didn’t do or say anything to stop them, everyone is complicit
@IamJasmine07 – Since they started using the following lines …. “Mind your business” “I do what makes me happy” “You can’t tell me what to do” Things have never been the same
@GodsgreatG – We’re living the “it’s not my business lifestyle” or the “as long as it’s not happening to me lifestyle.” Moral degeneration is the consequence of not speaking out or not taking communal responsibility. I know of hotels that won’t check in minors unless they’re with a guardian.
@ChawsBeau – We saw them cause they went to an Hotel. Do you know how many of this some of those area brothers enabled by allowing them use their room? Even some egbon Adugbo sef go dey knack such small girl giving so many excuse. E don be
Watch the video below to know more… | <urn:uuid:f0586c03-cfc8-489f-a49b-2211995176f1> | CC-MAIN-2023-40 | https://abenawrites.com/2023/07/18/trending-video-of-a-middle-aged-man-lodging-into-a-hotel-room-with-his-jhs-girlfriend-causes-stir/ | 2023-09-26T06:09:50Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.947552 | 451 |
Welcome to the Omni Barton Creek Resort & Spa in Austin, Texas! Whether you’re looking for a relaxing weekend getaway or an exciting adventure, this resort has something for everyone. From its world-class golf courses and stunning spa treatments to its delicious dining experiences and unique activities, it promises a memorable experience.
If you’ve been searching for your next dream vacation destination, look no further than Austin’s premier hotel: The Omni Barton Creek Resort & Spa!
Unforgettable Experiences At Omni Barton Creek Resort & Spa Austin Texas
Discover the ultimate vacation experience at Omni Barton Creek Resort & Spa. From luxurious accommodations to exquisite dining, this resort has it all. Relax and unwind in their picturesque setting of rolling hills and lush green lawns. Enjoy a variety of activities such as golfing, tennis, swimming, or spa treatments. With so many options available, you’re sure to find something that suits your needs and desires! Find out here
The facilities at Omni Barton Creek Resort & Spa, Austin, Texas, are top-notch, with plenty of amenities for everyone to enjoy. The staff is friendly and attentive, ensuring complete satisfaction during your stay. Take advantage of their convenient location near downtown Austin for easy access to shopping, entertainment, and nightlife spots. Whether you’re looking for a romantic getaway or an action-packed adventure, there’s something here for everyone!
A visit to Omni Barton Creek Resort & Spa Austin, Texas, promises unforgettable experiences every time you come back! Soak up the sun on the pool deck while sipping on refreshing cocktails from one of their bars or restaurants located throughout the property. Pamper yourself with a massage in their tranquil spa area or take part in some family fun activities like horseback riding or fishing nearby lakeside trails – no matter what activity takes your fancy, they have everything covered! Ensuring a relaxing and refreshing vacation stay each time you visit is what makes this destination truly unique – make memories that last a lifetime today! This content
Ensuring A Relaxing And Refreshing Vacation Stay
Experience the relaxation and refreshment of a stay at Omni Barton Creek Resort & Spa in Austin, Texas. This luxurious resort offers guests a variety of amenities to ensure that their vacation is as comfortable and enjoyable as possible. From spacious rooms with all the modern conveniences to an array of on-site activities, you’ll find everything you need for an unforgettable stay.
Whether it’s soaking up some sun by the pool or indulging in a massage at The Spa, there are plenty of ways to relax and unwind during your stay. Guests can also take advantage of the resort’s golf course or participate in outdoor activities such as hiking and biking trails through scenic Hill Country landscapes. Plus, with complimentary shuttle services available throughout downtown Austin, getting around town is easier than ever!
At Omni Barton Creek Resort & Spa Austin, Texas, we strive to make each guest experience unique and memorable. With attentive service and top-notch amenities designed for comfort, convenience, and relaxation – this is one place you won’t want to miss out on! With so much beauty surrounding us here in beautiful central Texas – it’s easy to see why this destination should be your first choice for an unforgettable getaway.
Discover The Magic Of Nature In Austin, TX
Discovering the magic of nature in Austin, TX, is an experience you won’t soon forget. From the lush green hills and valleys to the sparklingly clear waters, Omni Barton Creek Resort & Spa offers a unique opportunity to take in all that this vibrant city has to offer. Whether it’s enjoying a round of golf on one of their four championship courses or simply taking in the breathtaking views from your room, there’s something for everyone at this luxurious destination.
The resort features numerous amenities designed with relaxation and rejuvenation in mind. Spend some time unwinding by one of their two outdoor pools, or indulge yourself with a massage at their award-winning spa. There are also plenty of activities available beyond just lounging around; explore nearby hiking trails, kayak down Lady Bird Lake, or take part in guided tours throughout Austin’s Hill Country region. No matter how you choose to spend your days here, you’re sure to be surrounded by natural beauty every step of the way!
At nightfall, guests can enjoy delicious cuisine prepared by talented chefs who use locally sourced ingredients whenever possible. Sip on handcrafted cocktails while listening live music performances under starlit skies – truly an unforgettable experience! With so much to do and see within easy reach from Omni Barton Creek Resort & Spa, Austin, Texas, awaits those seeking adventure and relaxation alike!
At Omni Barton Creek Resort & Spa, you can expect to have an unforgettable experience. From ensuring a relaxing and refreshing vacation stay to discovering the magic of nature in Austin, TX, this is one destination that should definitely be on your list.
If you’re looking for an amazing getaway with all the bells and whistles that come along with it – look no further than Omni Barton Creek Resort & Spa Austin.
Important Information to Remember
- Location: 8212 Barton Club Dr, Austin, TX 78735, United States
- Website: https://www.omnihotels.com/
- GEO Page: https://email@example.com,-97.8604887,17z/data=!3m1!4b1!4m9!3m8!1s0x865b35f7e70b154f:0x30079355d76f41c1!5m2!4m1!1i2!8m2!3d30.291258!4d-97.8583!16s%2Fm%2F04vxz9z | <urn:uuid:7997f4dc-42d6-4e8c-ba80-ee5188e1e1f2> | CC-MAIN-2023-40 | https://abercrombiejewelry.com/omni-barton-creek-resort-and-spa/ | 2023-09-26T07:01:53Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.911863 | 1,244 |
ABG Corporate Finance has provided sell-side advice to the shareholders of ITM Communications (ITM) on its sale to Aliter Capital (Aliter). Financial terms of the transaction have not been disclosed.
ITM specialises in supporting critical ICT infrastructure for blue-chip private and public organisations. ITM has expert capabilities in five key areas: cabled & wireless connectivity, physical infrastructure, converged IP, offsite staging and logistics and site technical services. Based in Milton Keynes and operating nationwide, ITM is a leading player in a fast-growing market.
The current ITM management team led an MBO of the business in 2010 and are remaining with the business following the transaction to support the next stage of ITM’s journey.
Aliter focuses on investing in and growing SMEs in the UK support services sector. The deal is Aliter’s third investment from its second fund Aliter Capital II, which closed in October 2022. Aliter will support ITM in both organic and acquisitive growth.
Mark Barber, Director of ITM, said: “Since completing our MBO in 2010 we knew that one day we would want to realise shareholder value. Having spoken to several advisers we settled on ABG Corporate Finance who convinced us that they would run a well-structured process and strive to extract maximum value. Kristian led our engagement, moving us methodically and successfully through to deal completion with what was a sophisticated and experienced buyer. We would not hesitate in recommending ABG Corporate Finance, who maintained the highest levels of professionalism, attention to detail, patience, tenacity and good humour throughout our exit journey. Does what it says on the tin!”
Kristian Gavan, who led the ABG Corporate Finance team, commented: “We are delighted to have been able to advise the ITM team on a successful new partnership. Aliter has an exceptional track record in this sector and understood the business in great depth. Mark and the team are true entrepreneurs who have built a fantastic platform in an exciting market.”
For more information or to discuss how we may be able to help you, please contact Kristian Gavan (firstname.lastname@example.org) | <urn:uuid:8901fc9c-692f-4f0c-91ea-6791678555c3> | CC-MAIN-2023-40 | https://abgcorporatefinance.com/2023/01/18/abg-corporate-finance-advises-itm-communications-on-its-sale-to-aliter-capital/ | 2023-09-26T04:38:46Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.953286 | 458 |
So Everyone Can Game
Utilize our SpawnTogether fundraising resources and easily share facts about the life-changing mission of the AbleGamers Charity.
SpawnTogether is an annual celebration dedicated to gaming and inclusion for disabled players. What began as Steven Spohn’s birthday dream to raise one million dollars in vital funds for AbleGamers has evolved into a yearly fundraiser that supports our life-changing work throughout the year.
Creating opportunities that enable play in order to combat social isolation, foster inclusive communities, and improve the quality of life for people with disabilities.
AbleGamers uses the power of video games to bring people together, improving quality of life with recreation and rehabilitation.
The Power of Your Donations
$10 Helps provide essential equipment that make gaming more accessible to players with disabilities.
$25 Supports the AbleGamers Peer Counseling program that equips players with disabilities with life-changing tools and support.
$50 Contributes to advancing research and advocacy for accessible gaming.
$100 Supports adaptive gaming programs, accessible gaming nights and inclusive partnered events.
$250 Significantly impacts the mission to break down barriers and create an inclusive gaming landscape.
$500 Sends a powerful message of acceptance, inspiring positive change in the gaming industry.
$1,000 Donation represents a profound commitment to making the world a better place for players with disabilities. Your generosity leads the charge in fostering an inclusive and accessible future for gamers worldwide.
Spread the Word, Share Inspiring Stories!
Kick-start your SpawnTogether fundraiser with a story about why you’re supporting AbleGamers and highlight the importance of your fundraiser by sharing some of AbleGamers’ impact stories. | <urn:uuid:4ba1ca75-fba4-4eb0-9070-cf8acbacb00c> | CC-MAIN-2023-40 | https://ablegamers.org/spawntogether-resources/ | 2023-09-26T05:40:52Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.901038 | 364 |
Software Engineer, Architect, and Consultant in Greece
More than twenty years progressive experience in realizing complex software systems. Currently focusing on Oracle ADF and Fusion Middleware technologies. Author of Oracle JDeveloper 11gR2 Cookbook.
Development Environments/Technologies: ADF, WebLogic, Oracle Fusion Middleware, J2EE, JSF, XML, Tuxedo, UML, MFC, .NET, EDI, Other
Database Systems/Technologies: Oracle, PL/SQL, SQL, Other
Programming Languages: Java, C++, C#, C, Other
Operating Environments: UNIX/AIX, Linux, Windows, Other | <urn:uuid:b6bdedbd-8bc3-46cf-ae3f-41d0ff2ce6cf> | CC-MAIN-2023-40 | https://about.me/nharalabidis | 2023-09-26T05:45:46Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.727 | 148 |
These pecan shortbread cookies are everything you want in a cookie– they’re buttery, nutty, and have just a hint of sweetness!
These sourdough discard doughnut holes are a delicious and easy treat– for breakfast or dinner! Crisp on the outside, light and fluffy on the inside, and with just a hint of sourdough and cinnamon. They’re also extremely versatile; you can dip them in chocolate sauce, coat them in powdered sugar, or even stuffed them with your favorite jam or filling. Let’s get baking!
I decided to combine my three favorite things: brown butter, sourdough, and brunch… and all I can say is wow! These cinnamon rolls have it all— they’re warm, slightly nutty, sour and sweet— all in one! If you’re a fan of big, doughy cinnamon rolls that pack a strong cinnamon punch but aren’t too sweet, you’ll be a big fan of these! Time to feed your sourdough starter and get baking! | <urn:uuid:adb9a81a-1ad4-4ade-bf9d-6436f61089d9> | CC-MAIN-2023-40 | https://aboutdinnerthyme.com/category/eat-seasonally/winter/ | 2023-09-26T05:41:02Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.903048 | 224 |
India, a land known worldwide for its diversity, culture, history and tradition, has many firsts to its credit. We list some of these facts about India for you.
1. Land of Many ‘Firsts’, India Invented Snakes & Ladders, Shampooing, Algebra and More!
Many concepts and objects find their origin in the country that is India. From games like chess, snakes and ladders to things like buttons and diamond mining originated in India. We are the ones who gave the World the concept of zero and pi, along with algebra and trigonometry. The fact that there is water on the moon was our discovery.
2. The Highest Cricket Ground in the World
Isn’t it only natural that a cricket-loving nation should be home to the highest cricket ground in the World? This cricket ground is situated in Chail, in the State of Himachal Pradesh, at 2144 metres above sea level.
3. India is the Second Largest English-speaking Nation in the World
Almost 10% of the country’s population is fluent in English, which is second only to the US. This figure is expected to quadruple in the next decade.
4. The Second Largest Network of Roads in the World
The country has around 1.9 million miles of roads, making it the second-largest network of roads in the World, second only to the USA.
5. World’s Highest Rail Bridge in Jammu
The arch-shaped Chenab bridge is 35 meters taller than the Eiffel tower, making it the World’s tallest bridge. It stands at a height of 1178 feet over the Chenab river.
6. Bandra- Worli Sea Link has Steel Wires Equal to Earth’s Circumference
This is not something that most people know. Each of the cables is capable of holding 900 tons of weight. The weight of the entire establishment is equivalent to that of 50,000 African elephants.
7. Most Visited Place in the World- the Golden Temple in Amritsar
As per the World Book of Records, The Golden Temple is the most visited place in the World, with over one lakh devotees visiting the shrine daily.
8. The Highest Motorable Road in the World
Ladakh in India is home to the World’s highest motorable road at an elevation 0f over 19,300 feet.
9. Biggest Family in the World
Mr Ziona Chana is the head of the World’s largest family of 181 members. He has 39 wives, 94 children, 14 daughters-in-law and 33 grandchildren. They all live in a 100-room mansion in Baktawng village of Mizoram.
10. The Largest Number of Vegetarians in the World
If you are a vegetarian, then India is the place for you. With most of the population comprising Hindus, around 29% – 40% of the people are vegetarians.
11. World’s Largest Milk Producer
Indis holds the record for being the World’s largest milk producer. It produces almost 155.5 million tonnes in a year.
12. A Day dedicated Dr A.P.J Abdul Kalam in Switzerland Called Science Day
Dr Kalam visited Switzerland on May 26, 2006, and that day is nationally known as Science Day in Switzerland.
13. World’s Only Floating Post Office
We in India have our very own Floating post office on the Dal Lake in Srinagar. Perched on a houseboat, it is also home to a philately museum.
14. Varanasi, One of the Oldest Inhabited Places in the World
Almost 5000 years old, Varanasi is situated on the banks of the Ganges. According to Hindu mythology, the city was founded by Lord Shiva.
15. Mysterious Anti-gravity Hills in Ladakh, Magnetic Hill
Having an anti-gravitational effect, this is a magnetic hill in India. It is landmarked by a yellow notice board that spells out instructions and asks visitors to put their car in neutral gear on the spot marked by white paint. And then, the car will begin to move uphill on its own.
16. Mawsynram- the Wettest Place on Earth
With 11,873 mm of rain annually, this town in Meghalaya is the wettest place on earth. It holds the Guinness world record for this. The place gets so much rain due to its proximity to the Bay of Bengal. This region’s winter months are spent preparing for the six-month-long monsoon ahead.
17. The Number of People Travelling on Indian Railways Every Day is Equal to the Population of Australia
Connecting more than 7172 stations, India Railways carry about 23 million passengers daily in 12,617 trains.
Also Read: 25 Best Places to Visit in Australia
18. Benny Prasad: Fastest Man to have Travelled Around the World in 6.5 Years
This instrumental guitarist from India, who is the first one to have designed the World’s first bongo guitar, holds the world record for visiting 257 countries in six years, six months and 22 days.
19. Lake Formed by a Meteor
Lonar lake in Maharashtra was created by a plummeting meteor about 52,000 years ago. This lake is a 4-hour drive from Aurangabad. Travel enthusiasts must not miss this astronomical marvel and the temples around it.
20. World’s First Hospital Train
The Lifeline Express, the Jeevan Rekha Express, is the World’s first hospital train, taking its services from surgeries to cancer treatment to remote villages.
21. Largest number of Mosques
With almost 300,00, India has the largest number of mosques in the World.
Hope you enjoyed reading about these facts about India. | <urn:uuid:301a248e-5e98-432a-96a4-51d8f727aa5a> | CC-MAIN-2023-40 | https://abouther.in/facts-about-india/ | 2023-09-26T05:21:43Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.934982 | 1,242 |
Technology Management Concepts is humbled and proud to announce that we have been named to the prestigious Bob Scott’s Top 100 VARs for 2023!
Our devotion to innovation and leadership in growth drives us. It’s an honor to be among our industry’s giants and still make it to Bob Scott’s Top VAR Stars. Being a reliable tech partner means staying current with customers’ wants and needs. We pride ourselves on our ability to develop technologies that help solve operational challenges. By providing ongoing support and staying current on trends, we keep our clients’ competitive edge. Our experts specialize in implementing financial and business management systems designed to streamline your processes, increase your productivity, and meet your accounting needs. We are proud to have recently been featured as a “Best Workplace in the USA” by Inc Magazine, Accounting Today’s VAR 100, and certified by the Women’s Business Enterprise National Council.
Our focus will always be on achieving our clients’ goals with ease and confidence. Let us partner with you to create a nurturing experience to maximize your potential. | <urn:uuid:c7055327-b79d-4906-8892-70660e5264f6> | CC-MAIN-2023-40 | https://abouttmc.com/blog/2023-bob-scott-100-var-stars/ | 2023-09-26T06:44:50Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.948831 | 230 |
Sunday 22 September, 17:00 – 18:00
The Abu Dhabi Host Committee invites all participants and accompanying persons for a warm and festive welcome reception immediately after the opening ceremony. All guests will be treated to drinks and a selection of typical Emirati food in the perfect setting for catching up with old friends and making new ones.
Tuesday 24 September, 06:00 – 07:00
For the eighth year the FIP congress will include a 5km fun run. The FIP Fun Run is an excellent event promoting a healthy lifestyle, and an alternative networking opportunity for delegates. We ask runners to register their interest in advance, as places are limited. The 10 Euro fee is a donation to the FIP Foundation, which helps the development of programmes to advance the pharmacy profession. The fun run/walk starts at 06:00 sharp and consists of a 1km loop x 5. Make sure you arrive on time.
Dress code: Shoulders need to be covered, no bare midriffs – a T-shirt and shorts will be fine.
Tuesday 24 September, 19:30
Pacifico Tiki Bar & Restaurant (address on the ticket)
Monday 23 September, 20:00 – 22:30
YAS Marina (Formula 1 Racing) Circuit (address on the ticket)
Academic Pharmacy Section
Clinical Biology Section
Community Pharmacy Section
Health and Medicines Information
Section Hospital Pharmacy Section
Industrial Pharmacy Section
Social and Administrative Pharmacy Section
Thursday 26 September, 19:30 – 23:00
A lavishly imagined dream, Emirates Palace offers you a magical location to enjoy the quintessence of award-winning 5-star luxury hospitality and authentic local experiences. With its award-winning culinary cuisine, Emirates Palace is the definition of an unrivalled Arabian fantasy. Located in the heart of Abu Dhabi, Emirates Palace is grand in both its design and myriad of offerings. From a 1.3 km pristine beach, landscaped pools and a private marina overlooking a natural bay, Emirates Palace is perfect for a once-in-a lifetime ethereal experience. Emirates Palace is truly one of the most inspiring hotels in Abu Dhabi, and we look forward to welcoming you there for a magnificent closing dinner for this congress. The address of the venue is printed on your ticket.
Tickets for all the above-mentioned dinners may be purchased when registering online for the congress. | <urn:uuid:28fdcf0b-aa3e-4033-8bc4-6f7e00b1a884> | CC-MAIN-2023-40 | https://abudhabi2019.fip.org/social-events/ | 2023-09-26T05:31:52Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.88676 | 505 |
Abwaab | Sales Team Lead
You will be joining a startup that is changing the way students learn outside the classroom across the region, and witnessing the thrill of building a hyper-growth tech company.
As we work towards this mission, Abwaab is looking for a talented, passionate, impact driven, growth mindset, high performing, well organized leader to join our Sales Team.
Provide leadership and guidance to the sales supervisors and agents within tele sales.
Develop and implement sales strategies and tactics to achieve sales targets.
Monitor and analyze sales performance metrics, identify areas for improvement, and take appropriate action to drive sales growth.
Conduct regular meetings and training sessions to coach and motivate the sales team to ensure their continuous development and success.
Collaborate with other departments, such as marketing and operations, to align sales efforts with overall business objectives.
Foster a positive team culture, encouraging collaboration, teamwork, and a customer-centric approach.
Stay updated on industry trends, market conditions, and competitor activities to maintain a competitive edge.
Assisting in developing sales pitches and scripts.
Bachelor’s degree in Marketing, Business Management, or a related field.
Previous sales leadership experience, preferably in telesales or call center industry.
Strong communication and interpersonal skills to effectively lead and motivate a team.
Proven track record of meeting or exceeding sales targets.
Analytical mindset with the ability to interpret sales data and make data-driven decisions.
Familiar with CRM systems and sales tools.
Excellent organizational and time management skills.
Flexibility to adapt to a fast-paced and changing environment. | <urn:uuid:1272b512-0939-419c-9687-ee5a68bf5646> | CC-MAIN-2023-40 | https://abwaab.freshteam.com/jobs/XARAoiiqijN3/sales-team-lead | 2023-09-26T05:35:05Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.905074 | 353 |
Top 4 steven tyler cbd gummies ? Best CBD products uk ABZ Private School Best CBD oil for recovery.
Fortunately, they have been preparing for this crusade for a long time, and they have been very thoughtful.
It seems that the outside is just a layer of stone sand, and the inside is also made of cold iron.
This is an endless loop. The brilliance of cross border transmission lights up.Soon, 300 beholders and three leading beholders appeared in the alien spaceship of the spiritual civilization.
The star beast package and the hound beast package are all complete. Xu Qiji said, and handed it to Miehuang. Have a glass green county cbd oil of water.This is clear water with a steven tyler cbd gummies part of the Holy Spring added, which can greatly increase the mental power of Doctor Mohuang.
Xu As expected of Mr.Xu I do not know how essential oils to reduce anxiety he did it, but it is amazing It is too late to think about it, no matter what the reason is, take advantage of it is illness and kill it.
All the survivors retreated, hid in the depths of the hidden survivor base, stopped going out for a short time, and avoided the raiders operations as much as possible.
Zhang Ping Zhang Banpo, seven in Why can t I sleep at night .
- cbd gummies 1000mg
- cbd gummies walmart
- keoni cbd gummies
- negative side effects of cbd gummies
- cbd gummies joy organics
Can t sleep and have to wake up early and seven out, has Lao Gao arrived home It is here, I have already got off at the train station.
The three clones were not left at home, but were dispatched by Xu Qiji early in the morning to cbd store clayton nc conduct various experiments.
Prepare both hands. Parliament of the Smoky Empire.The army on the edge of the Empire is Supreme Pillar has all been charged, and the three star ship is on mutual alert.
Li Zichi quickly echoed.Facing Does CBD water make u high .
What are signs that I have anxiety & steven tyler cbd gummies
How to get away from work stress the different gazes of the younger brothers and sisters, Yan Tiannan sneered and said indifferently, I want to see, this Han Yunxi has no ability at all, if there are no two monsters by his side, he is afraid that he is even mine.
Xu Qiji is drop shaped body vibrated.The God Ancestor messenger with a look of I understand satisfaction, withdrew from the nine ancestor messenger space.
It is you. One of the cbd gummies for anxiety walgreens men in black did not even think about it.Anyway, he felt that Xu Qiji is avatar was related to him, so he grabbed the avatar and walked out.
Having said that, the two stars steven tyler cbd gummies above Xu Qijing is head shone brightly. After a while, the eyes they looked at Xu Qiji became hard to say.Are there other members Xu Qi stared at the space, and after a long while, no other members emerged except Shi Yihua and his brother.
With his place as the center, if you drive all the way without rest, it seems that every desert can be reached in about two days and three nights I knew I would go out in several more clones, so that I could release a message every once in a while.
There are tens of thousands of people in Huangquan Hall, and many of them are masters.
The channel and method of spreading the practice , do you know does cbd oil increase red blood cells it, teacher Xu Qi was pleasantly surprised, and the aurora in his eyes could not help but turn around in circles.
Relying on his ranking among the Six Saints, he actually made a lot of nonsense in front of me, threatening to keep Xiaolan in the town for the rest of his life.
When Xu Qiji also fell asleep, a little hamster quietly crawled over pressure weed outside the room.
Tacit agreement The saint took the bear pillow that was one person tall.Although it felt bad, she could only use it together at this time she slapped the bear pillow hard Boss Xu, I think your shortcut to promotion is very promising.
The bed lying under the body has been changed from 1.5 Meters to 2 meters, which can be rolled back and forth without worrying about turning over too large and falling off.
Obviously, this is the effect of the Daxia System. After Xu Qijing sensed the starlight, he was sure of this in his heart. I just do not know the few members who have advanced lemon cbd flower to the second cbd withdrawal headache realm.Can you avoid this link Furthermore, it may not be limited to the Daxia System.
The owner of Zhentian Pagoda, a figure standing on the top of martial arts.As his daughter, is it a good thing or a bad thing Besides, what if Xiao Qiao was not her daughter What would that be It is terrifying to think about it.
This punch, she did not hit the ghost king.Witnessing the dark space crack that could not be healed for a long time, Han Yunxi is steven tyler cbd gummies mouth was half open, her eyes widened.
This sword was blunt and heavy in appearance, but it was extremely hard.Even the hard work created by the master casting masters would not Is vaping CBD addictive .
Does hemp work as well as CBD ?
How does corticosteroids reduce inflammation dare to compete with Juque.
Xu Qi still closed the e reader and put it back in the drawer.No matter how fun things are, you can not get tired of playing them in one go, otherwise you will lose a lot of fun in the future.
And those college girls fell from the edge of the cliff with their heads in different places.
The Smoky Empire is at the highest council in the 713 world.In front of the President of the Supreme Council was a plate of pills with white smoke.
He really does not have that much time to waste. Thinking of this, he put his hand on Su Xisha is avatar Hey, Mr. Su I have something to ask you. Yes, talk. Su Xisha replied.I put runes on the sword holes, do I put them on whatever I want Or will there be some kind of formula Xu Qiji asked.
If Xiaoyao Academy had such outstanding students, then he would die, and he could be considered worthy steven tyler cbd gummies of his master is teachings back then.
Squeak Go away This time, Brother Miao is squeak sound, even without the translation of Qi Yishan is body, Xu Qiji can understand the meaning.
Next, it is my time, iron men. After giving up the huge size, its speed became extremely exaggerated.With a flash, he came directly to the side of Captain Phoenix Slayer, and the speed was so fast that it was almost invisible to the naked eye.
When Doctor Phoenix Mie went out, Xu Qiji did not stop her after all, if she stayed here and asked what experiments the couple were going to do for a while, Xu Qiji felt a little hard to answer.
So today is star beasts are extraordinarily active.Awakeneds all over best dosage for cbd the world, gritted their teeth and started overtime mode.
But I do not dare to move. Xu Qijing counseled.At least until he has the ability to steven tyler cbd gummies Smilz CBD gummies fox news transfer the planet is inhabitants to it.
That is her identity Thinking of this, even though Medical Saint Gui is one of the Six Saints, he still faces Bai Qin and clasps his fists respectfully.
Bullshit or not, it does sound reasonable. If you feel that you have a lot of blood, just try it.Many worlds use blood sacrifice weapons to strengthen the rules of the connection between yourself and the weapons.
This is a boring curse restriction.Sooner or later, I will break sour cbd oil gummies this restriction and raise the ashes of the old island owner.
We are in dark map mode, but the enemy has a full map view.Did we bring the Great Cataclysm down, causing the world is rejection The MPs were speaking, and they felt very bad.
Han Yunxi has completed the contract with these artifacts.No matter where they are, as long as help you fall asleep he wants to summon them, they will return in an instant.
Selling yourself Phoenix is eyes lit up, and he seemed to be interested. When the time comes, I will send you the appearance of money.Let is gather the power of Daxia to find out if there is money in this world.
I can not believe that Huangquan Palace still hides a powerful person from the six How to get rid of my anxiety naturally .
How long do CBD pills last ?
CBD gummies for muscle recovery star reincarnation realm.
But they are not mindless and reckless, and they are also quickly discussing countermeasures while attacking.
The photo on the certificate is of him smiling Han and she steven tyler cbd gummies smiling sweetly.In the texas naturals cbd name column, the two names Xu Qiji and Shen Thrush were printed respectively.
What the hell is this Han Yunxi stared at the darkness below, and landed freely, and the wind from her ears became more and more hot.
Superpowers, even if there is a foreshadowing of the world change news, and the old Gao family incident yesterday, but facing the fact that her own man has become a superpower, she simply accepts it without any reaction.
High rise buildings collapsed, explosions were heard everywhere, and flames burned in the rubble of steven tyler cbd gummies the city.
The red haired senior brother nodded again for example, the whole family was sterilized He said to Xu Qiji Come on, grab me.
Dinghai is a sword.Xu Qiji put away the sword handsomely without the scabbard, the sword could only be carried on his back.
Just do.The world how to treat severe knee pain of 713, his own world, if he wants to achieve a great consummation, he must improve his realm at the fastest speed and reach the top Therefore, even if the three eyed dog suddenly appeared and interrupted his good deeds, he would not be annoyed at the other party.
How many hairs does Balupi lose to make so many design drawings Xu Qiji could not help but reached out and touched his forehead.
Looking around, it was bleak. Sitting on the cliff like this, from the evening until the night.The woman yawned lazily, suddenly felt a little hungry, and hurriedly took out the dry food she carried with her and ate it.
The blank clone just stood there, motionless.It is a bit scary to look at, because the blank avatar has no facial features, and it is a bit of a ghost movie.
But his habit of sleeping every day is still there.After all, he just woke up a few days ago, and the habit of more than 20 years will not be so easy to change.
I think you should practice here with peace of mind first.Xiao Qiao knew that his Ice Dragon Transformation could raise three stages of cultivation in the Reincarnation Realm.
After all, the wrath of her grandfather, the Evil Emperor, will lead to the destruction of the entire Canglan Continent Silly girl.
Come on, I will accompany you when you want to relax. Su Qiqi nodded. Xu Qijing is eyes lit up and said, I can also accompany you.I am going to serialize the comics in the finale, and I am just ready to go to collect stories.
Moreover, he also felt more and more that the guy in front of him did not look like his junior sister.
Xu Qiji reduced the design drawing again.He did not close the document, but slid the mouse until the end of the design drawing Xu Qijing steven tyler cbd gummies wanted to see if there was anything like an instruction manual for this thing.
Along the way, several people talked a lot about the current situation of Huangquan Hall.
At this time, after Xu Qiji is 3 Jin 4 What is medical marijuanas used to treat .
How can I reduce inflammation fast ?
CBD gummies for productivity Heavenly Tribulation was formed, the first target was not Xu Qiji himself, but on the black grains in the void.
It may be some kind of instinctive subconscious, so Xu Qiji took it with him.
But before the dense fog could wrap Lu Yuesheng, the other party jumped up into the sky with a movement that was as fast as a meteor.
In this case, these artifacts of yours can all regain their strength Fuck Why did not I think of it stress relieving medication Han Yunxi stood up excitedly.
Thrush was cute when she played the role of Qi Yishan seriously.It might be fun to play this kind of role playing game on weekends for a different rough guy, but it will not be so smooth to accept.
A terrifying aura that dominates the world instantly enveloped the entire sixth floor void The peak of reincarnation This woman is actually in the same realm as Ning Changsheng, is this Dare to ask that senior is Xiaodie Han Yunxi quickly raised her 400x gummies cbd hand and asked.
He can not think of who the murderer could be now.Because if the other party was one of the three, Ghost King, Bai Pao, and Dark Beast Master, just based on Dongfang Ye is steven tyler cbd gummies Best CBD products for fibromyalgia current cultivation in the Star Sea Realm, he would have died in ABZ Private School steven tyler cbd gummies the village just like Dean Yi Yun and the others.
Do not you have Xiao Qiao, why are you suddenly interested in other women Remember what my teacher said back then, my grandfather did the same.
Shortly after Han Yunxi is voice fell, a ray of white light suddenly burst out from between his eyebrows, and finally turned into a thick white mist and appeared in the room.
This is for you.Mie Feng, who was in his sister is arms, stretched out his hand and took out a small chip from his pocket.
Furthermore, even if it cannot be rescued, it does not matter.With the technology of the 713 world and the knowledge heritage of the Smoky Empire, as long as you have just died, you can extract a large amount of information best place to buy cbd cream near me from the brain, which is more efficient than interrogating living people.
On the IOU, a long paragraph has been written.IOU Today, I purchased a jade talisman Jade Talisman of the Thousand handed Buddha Palm from Miaomiao on steven tyler cbd gummies credit, which is worth 8 third grade energy stones.
50 Off for the first purchase, which is converted into 4 third grade energy stones.
The weird bone blade in its hand stretched out, touched the throats of Su Qiqi, Yang Yue, and Zhang Banpo, and slashed lightly.
The two were close to the clouds and flew owly cbd gummies review faster the alchemist kitchen cbd and faster. But the figure behind was getting closer and closer to them.Clouds and mist lingered in her ears, Xiao Qiao clenched her teeth and stared at the eastern sky, no matter what, she would save Han Yunxi.
Cough, stop.Since it is confirmed that humans in World 713 can also cultivate, then I will bring you a few.
What do you mean by me Han Yunxi lowered her eyes and clenched her hands into fists, already wearing God destroying gloves.
They appeared from outside Does smoking CBD lower blood pressure .
Will CBD oil help lower cholesterol ?
How to sell CBD to retailers the sky two years ago, and they are still frequent.
If it is an energy body, he can stuff this thing into the door of ABZ Private School steven tyler cbd gummies miracles and transmit it to his own world.
After the 9th layer of the outer sky defense was broken that day, those spiritually civilized guys have quickly become familiar with the new depth of the invasion of the world these days.
He, whose figure was illusory like an afterimage, suddenly charged towards Han Yunxi like a thunderbolt.
Just like Gao Cuan at the time, ordinary people with particularly powerful mental powers comestibles de cbd can also come into contact with the shadow world.
This is to avoid falling into the eyes of Bai Pao and others, and Han Yunxi also agrees with this approach.
For example, a pupil technique that can see through everything, and the golden light in the eyes can even just cbd lab results reach the sky Next, when you collect steven tyler cbd gummies the remaining thousand runes, pay attention to similar runes.
Only Xu Qiji was left in the entire space. So, he started to hartluck cbd coupon jump up and down in this space.It looks like an ordinary spiritual space , but every time he jumps over on the seat of an envoy https://www.healthline.com/health/best-cbd-products-for-acne , he feels like the stars are moving, and he feels https://www.forbes.com/health/body/cbd-and-alcohol/ motion sickness and nausea.
Qi Yishan felt guilty because of her guilty conscience, so the pair seemed to be Talking eyes, began to look at Xu Qiji pleasantly.
In terms of swords, which shape do you like Su Xisha asked after turning Xu Qiji is mental body over.
If in the past ten years of practice, if the quality of the skills finally cultivated is insufficient, it is necessary to extend the work period until the minimum requirements for ten years of skills are met.
Xiao Qi was stunned in place, and she was dumbfounded. Now he can understand that the so called family is her fiance.Acid The acid flow in my heart is turbulent, and it is difficult to control myself.
When he first steven tyler cbd gummies awakened, his mental power was insufficient, and the black iron area could only exert force from his dantian, covering the abdomen position, hence the original code name black belly.
When he laughed, he would show two small tiger teeth, which made him look a little cute.
Then, she gently probed with her jade hand, and a burst of energy drilled through the void and suddenly attacked Xiao Qiao The sudden attack made Xiao Qiao quickly swept the sword away without even thinking about it.
Thrush was also thinking so, she stepped forward and leaned on Xu Qijing is side, her arms stretched out to where Qi Yishan was.
Now, she has more important things to do.Early in the morning, a ray of sunlight filtered through the curtains again and shone on Xu Qiji is eyelids.
And you, what are you going to do next Qing Ruo suddenly stopped, like a true god, overlooking the ants.
Coupled with Han Yunxi is amazing recovery power, Duanmu Jin burst into tears when he saw this scene.
The Holy What can help with anxiety attacks .
Best natural supplements for sleep :
- doctor auckland cbd
- best cbd strains for social anxiety
- cdb in marijuana
- cbd in the bible
- diet plan for inflammation
Can you use CBD in the military Maiden wanted to train 50,000 elite disciples as soon as possible.If possible, he hopes that the saint and brother Miao can bring Is CBD american shaman legit .
How to deal with high anxiety & steven tyler cbd gummies
How to relieve stress during exams more powerful people over.
The seven ancestors of Tiandao vomited blood at the same time.In the face of the oncoming fire lotus, even the ancestors of Tiandao could not help but closed their eyes as if resigned.
Hearing this, Han Yunxi nodded happily. In the past six months, I have practiced a sword skill with my teacher. Now, I finally have a real killer move.The real killer move My strongest ultimate move before was the Penitent Death Bullet of the Drunk Eight Immortals.
At this time, the giant beast behind had already rushed over.After seeing that the treasure it guarded was taken away by humans, the giant beast was furious on the spot.
The big sword cooperated with the doubling, and turned into a state that matched Xu Qiji is height of 20 meters at this time.
After eating some sweets, the pain of the huge thrush seems to be suppressed a little.
Behind the door, there seems to be a light coming from across the border.That light hit the Do CBD gummies help with focus steven tyler cbd gummies hamster in the cage on the side All of this happens in the state of overclocking acceleration.
Hahaha, then I look forward to the arrival of the ancestral envoy.The emissary of mechanical life stretched out his finger and projected steven tyler cbd gummies a smiley expression pattern, and his figure also dosagem cbd ansiedade receded from the messenger space.
Just take a step forward and you will appear in the east, and take a step back and you will come back to the west.
Energy conversion, energy extraction, but these are all appearances.Xu Qiji is divine eyes, spanning countless distances, stared at the black pillar forest, analyzing their structure.
Poison gas spewed out from behind the tail, and soon filled the entire small shadow world.
But Xiao Qiao must not die Thinking of this, Han Yunxi ran to the main entrance again.
Is it a one time external force It is a pity.Feng Shui regretted I was thinking, if possible, I would like to learn more relevant information and experience in dealing with that level of star beasts.
It has a great impact on the soul power, and it may cbd effects be able to restore Qin er is injury.
To maintain this small gate of miracles can cbd help loose weight , you can extract Xu Qiji is spiritual power and liquefied gas it can also be done by consuming black energy stones.
Looking at his stubborn appearance, Han Yunxi could not help but smile bitterly.
Xu Qi said silently.Xiong Ba, do you want to go to the future to copy the manuscript Hahaha Even I can https://www.forbes.com/sites/sophiesaintthomas/2022/03/17/the-5-best-cbd-oil-brands-in-the-uk-for-2022/ not get that weed gummies to sleep kind of thing.
Star beast No, the breath is different.Xu Qiji looked at the monster that came out of the space whirlpool from a distance.
Then, she ran to the dungeon world to see if she could help.With the strength of the projection of Saintess Le, it is enough cbd owner to go to the first floor of the dungeon and arrange some enchantments.
Anyway, the body is just a cloud of black smoke, wearing Nothing really makes a difference.
He changed his words and suddenly said Miss Dugu, Sect Master Han, I still believe that the real culprit of this incident is someone else, neither you nor What can you do to get better sleep .
Why does deep breathing reduce anxiety ?
Is CBD oil good for asthma the Huangquan Hall, and I will reveal it later.
On the barrier of the clan, let the star core can suppress it for a longer time, and give yourself enough time to buffer.
It is just that in Xiao Qiao is eyes, she does not exist at all.Brother Han, where will you be now Xiao Qiao pursed her lips, feeling very uneasy in her heart.
My venerable Huangquan Hall, only Qing Rui is the only one. Apart from that, there is no one else.Then you teach me yourself The coquettish and cute look is particularly touching.
Then, it takes a breath or two to get started. Easier than learning to ride https://www.forbes.com/sites/katieshapiro/2019/11/17/holiday-gift-guide-2019-the-best-cbd-beauty-splurges/ a bike You have to try it back.It is best to add the exercises from the Daxia System to strengthen the opponent is comprehension.
Pill Pavilion is a circular three story pavilion, like a cauldron, buckled upside down on the ground, with a very strange architectural style.
Although I do not know the effect, it should be the type that I have not collected.
These eyes are so beautiful that he could not help but want to dig out the pair of eyeballs and take them for himself.
It stands to reason that the black robe is one of the pillars of her grandfather is account, and she should appreciate him as much as her grandfather.
When his legs were running wildly, he always felt a little weight off balance.
The stronger the catastrophe, cbd store fairfield ohio the more powerful the welfare will be.Xu Qiji is wave of 3 Jin 4 just tinkered with the picture of the gathering of ten thousand tests for anxiety dragons, and also triggered a small probability of inner demons, and the welfare that finally arrived was naturally extraordinary.
You said it as if I was afraid of their Huangquan Palace.I have to go with you, wait for me, Sister Dugu Xiao Qiao knew that this trip was extremely dangerous.
Beside her, a bald man guessed.While speaking, the two of them looked at a man with shiny skin next to them, and they recognized at a glance that he was not an islander.
The progress bar of the black column rises at a slow but firm pace.Will the progress bar of Black Pillar be filled up in advance, will it cause an aberration But in the current situation, mutation is what I need.
Instead of killing and wasting, it is better to send the prisoners to the prison here and become sacrifices to fill the black column.
The white robed man standing in the dark fog finally pushed his outstretched hands forward like a judgment.
Then, you can cook and drink it for a while and try it yourself.After all, you do not have a daughter in law, and no one will cook medicine for you.
With Xu Qiji is current strength, he summoned thousands of blank clones in one breath without breathing.
Seeing Long Su is attitude, Long Luoyao secretly clenched her fists and looked into Xiao Qiao is eyes, as if a flame was burning.
Intimate wheat ears, these cute emoticons of yours, it will be me in the next second Although many of these emojis are too cute, they can only lie in the Is CBD legal in montana .
How to relieve severe pubic bone pain during pregnancy ?
Best doctor for anxiety system and eat ashes, but this does not prevent Xu Qiji from collecting them.
For example, the top phoenix extermination team, black bellied captain and other members, it is estimated that in a few years, they will be able to step into the third rank and hit the fourth realm.
But in this 713 world, even these little cute new wools who are just getting started have not escaped being stabbed.
Just as the assassin was preparing to escape , a long prepared blessing fell on him.
Good. The medicinal soup is the kind I have been drinking in recent years.Thrush should know the formula, I will ask Thrush later and send the formula to you.
Xu should be able to use it in the future.There is also a beast amulet under the box, which has the same effect as a pill.
If there are not many Awakeners in a certain area, then the Awakeners have to rush to Area B after a short rest after hitting Area A, and are tired of running around.
Then, the mask that pretended not to be seen through was taken away.Although he reacted immediately and quickly put the mask back on, the aura of being a human has been captured by the black smoke jailer.
Just when he was extremely worried, a figure slowly condensed behind him.Xu Qi felt something in his heart and looked back 713 The figure slowly condensed and formed, with long eyelashes, a beautiful nose, fragrant red lips, and shoulder length hair.
Xu Qi is home. It is all gone Are there any survivors a captain level member asked. I am going to take a look. If there is a living mouth, I will bring it back.These ants are very strange at first glance, and maybe they have research value.
Xu Qiji made every effort to lemon cbd flower steven tyler cbd gummies activate the artificial divine eye to mobilize the knowledge contained in the divine eye. | <urn:uuid:37e37542-f731-4de1-b774-a60960c3686e> | CC-MAIN-2023-40 | https://abzschool.com/cbdenf/steven-tyler-pgvnbu-cbd-gummies/ | 2023-09-26T06:33:28Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.964443 | 6,178 |
Lion Pride Band
School Name: New Deal High School
School Location: New Deal, TX
School Mascot: Lions
Platinum Member Since: 2016
KHS Brands Used: Jupiter
About the Program: The New Deal Band is one of the elite class 2A bands in Texas; winners of the UIL Texas 2A State Marching Championship (2015) and the Texas Music Educators Association’s State 2A Honor Band in 2017. The New Deal band program from 5th-12th grade includes 300 of the school district’s 750 total students.
“The Jupiter family of instruments have consistently provided us with the optimum balance of quality and cost, which is absolutely vital to maintain a successful small-school Texas band program.” | <urn:uuid:8aff80e0-ed49-4093-a007-70a6604a189a> | CC-MAIN-2023-40 | https://academicalliance.com/new-deal-high-school/ | 2023-09-26T06:31:07Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.898578 | 158 |
aCalendar Store is available again in Google Play. At no time did aCalendar contains any malicious code or posed any threat to your device or data.
On April, 3, 2023 Google send us a suspension notice for aCalendar Store. Google claims, that aCalendar is violating policies.
aCalendar store is not doing anything malicious, but there are some non-standard mechanisms in place to assure that background synchronisation works reliable on all devices. We sent an appeal to Google on April 4 and on April 6 got a green light from Google Play to submit an updated version which we did and was approved on the same day.
Sorry for the inconvenience! | <urn:uuid:edad424b-6a24-4ab3-8ee5-f1b98bdea627> | CC-MAIN-2023-40 | https://acalendar.tapirapps.de/en/support/solutions/articles/36000432644 | 2023-09-26T06:27:07Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.906846 | 138 |
Preventing Commercial Water Damage
Water damage consistently ranks as one of the most common reasons for insurance claims among businesses. This damage is not just expensive; it can also create potential health risks and bring the productivity of businesses to a halt, costing additional time and money. Fortunately, various low-cost preventive measures can help reduce the threat of water damage.
Consider the following tips:
- Maintain heating, ventilating and air conditioning (HVAC) systems. HVAC systems are necessary for maintaining a comfortable work environment but can cause costly water damage when not maintained. As such, include HVAC systems in building maintenance programs to check that condensation collection pans, drains and condensation pumps are functioning properly.
- Conduct regular roof inspections. Roof leaks can lead to rot and mould growth and can damage surfaces inside buildings. Visually inspect roofs to verify draining systems are clear of debris and functioning as expected. Furthermore, arrange assessments with professional roofing maintenance providers to ensure that small deficiencies don’t become more serious problems.
- Prevent freeze-ups. During severe cold spells, sprinkler systems and water pipes can freeze, burst and cause devastating water damage. Identify all equipment, processes and piping that could be susceptible to freezing and add sufficient insulation. Drain and secure idle equipment, protect remaining equipment with suitable anti-freeze products and consider locating equipment in heated enclosures.
- Inspect sewage lines. Excess water created from sewer blockages can force sewage into buildings through floor drains, toilets and sinks. Consider asking a professional to inspect sewage lines regularly to facilitate early detection of blockages.
- Check water heaters. When water heaters fail, they release water and can cause significant property damage. Additionally, deposits accumulate on the bottom of water heater tanks and corrode tank liners over time. As such, regularly inspect water heaters for signs of failure and replace units every 10 years. Furthermore, automatic shut-off valves are a great way to limit damage in the event of a leak or unit failure.
To prepare for all eventualities and limit potential losses, consider implementing a water damage prevention and response plan.
Contact us today for further commercial property maintenance tips!Get a Quote | <urn:uuid:a7bb91f3-accf-49dd-bef7-e45213d9a4cf> | CC-MAIN-2023-40 | https://accessinsurancegroup.com/blog/prevent-commercial-water-damage/ | 2023-09-26T05:48:28Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.919759 | 449 |
Last night Melbourne hosted the Premiere of the latest in the exorcism world THE DEVIL INSIDE. Paramount Pictures sure know how to make it ultra creepy with crucifix’s everywhere, black birds flying overhead while fans rugged up outside preparing to watch the film. With a special introduction from a priest, mentioning that people where watching at their own risk. I also got passed a transcript for an Interview with Reverend Bob Larson about exorcism and how close the film relates.
You can check out the transcript of the interview below but scroll right to the bottom to check out the video from the Melbourne Premiere. THE DEVIL INSIDE is in cinemas now.
Rev. Bob Larson is the world’s foremost expert on cults, the occult, and supernatural phenomena. He has spoken in more than 100 countries and has appeared on scores of network TV shows such as Oprah, The O’Reilly Factor, and Dr. Phil. More than a dozen major television networks have produced documentaries about his work, and he has been featured on the front page of the Los Angeles Times, in The New York Times, The Washington Post, and other major newspapers. Bob has written 31 books, translated into more than a dozen languages. His books include four best-selling novels. His 575-page classic work Larson’s Book of World Religions and Alternative Spirituality is a standard reference encyclopedia at many colleges and seminaries. His latest book is Demon Proofing Prayers. He has starred as a real-life exorcist in his own TV reality show seen worldwide, “The Real Exorcist.”
Q: How grounded in reality, from your experience, is The Devil Inside?
A: “It is after all Hollywood and it is after all the horror genre but at the same time there are some aspects about it which are all too real. The two which come to mind are the issue of demonic transference and the scientific approach in verifying an exorcism, including the dilation of the pupils of the eyes.”
Q: What kind of person can become a practicing exorcist?
A: “Well it takes a religious person, a person of faith. It’s obviously a calling. It’s someone who feels deeply about helping other people. But it’s somebody who has a spiritual vocation. You just don’t become an exorcist and desire to have that knowledge and training. It’s really a higher calling.”
Q: What kind of preparation do you undertake before conducting an exorcism?
A: “Well, there’s a lot of knowledge that’s necessary and I’m speaking of an individual such as myself. Even the priests who are portrayed in the movie don’t just jump into it. The Roman Catholic Church has a ritual of Romana, which is a prescribed ritual but even if you recite a ritual, you have to know what’s behind it. Perhaps more importantly, the movie emphasizes that there are a lot of psychological issues which you have to work through to determine if it’s truly possession or if it’s some other phenomenon, so you have to have a working knowledge of various forms of mental health issues and various ways in which people respond physically and emotionally – which may or may not indicate possession.”
Q: How exactly does a person become possessed?
“Well that is an interesting question and it really does not come up in most of the movies. For example, the original The Exorcist only just briefly touched on it with this reference to a Ouija Board. The one thing that is consistent with all types of exorcism be it Protestant or Catholic or whatever, is finding out the original entry point of the demon because no demon can be expelled unless you discover what it is that got the demon there in the first place and that issue is resolved. There’s always a resolution of something related to the original cause of the possession.”
Q: What does a demonic presence need from the possession of a human body?
A: “It’s really pretty simple; a demon is an invisible spirit being. It has no capacity to do actual evil, it needs a physical body, so for example, a demon cannot rape somebody, a demon can’t pull the trigger of a gun and a demon can’t start a war. It’s through the body of somebody, if they’re sufficiently induced by the demon, that the demon accomplishes actual evil in the world.”
Q: Have you ever come to any physical harm conducting an exorcism?
“I have come to physical harm, but not often. I’ve since learned to be very, very careful. I had my ribs broken once, which was probably the most serious, that’s because I was not sufficiently careful. But there’s always the danger of violence and I will not do an exorcism ever alone. If I think there is going to be the potential of violence, I will always have several very strong men available. I’ve seen a case, in Australia actually, where I had 11 strong men hanging on to body parts of just the one man.”
Q: In The Devil Inside, there is a scene at the Vatican where students are being tutored on the subject of exorcism, is this common in reality?
“It is not common at all. In fact, of the entire Roman Catholic Church, that is the only sanctioned instructional institution. And as far I know, we are the only ones, even in the Protestant community who officially train people. Now there are others who in an ad hoc way try to give people instruction on how to conduct an exorcism but certainly not within methodical approach that we do. It’s something that’s extremely rare.”
Q: In the movie we are shown what appears to be ‘demonic transference’, which you have already briefly touched upon. Is that something you’ve actually experienced or just Hollywood fiction?
A: “Actually that is very real and something that you’ve got to be careful of. Demons are always looking for someone who is accessible, they will try to go into another body during the process of the exorcism, so the exorcist has to always be in control of the process so that doesn’t happen. Sometimes people unwillingly get demons by being in relationships with others who have demons. That can particularly happen in a sexual sense; we find that happening all the time. “
Q: How do you feel Hollywood has portrayed the subject of exorcism in the past?
A: “I think Hollywood has done a very poor job for the most part. That’s because they are mainly interested in entertainment and drama and the actual reality of exorcism may not be all that entertaining. So what you have in The Devil Inside is a horror movie and with that a certain amount of entertainment but the first half of the film is a pretty serious discussion and in that dialogue, you do learn more about exorcism than any other movie has ever communicated.”
Q: Would you recommend audiences go and see The Devil Inside when in is released in Australian cinemas?
“Well I don’t recommend it in the sense that as a spiritual person there are elements in the movie that I’m a little uncomfortable with. However it is reality and it is Hollywood, but if you want something that comes closer to authenticity, this is the movie that has it. And it’s also a pretty scary movie, even for me there were times when I jumped out of my seat!” | <urn:uuid:04b65494-449f-42a1-9715-7a6c17e7fd3c> | CC-MAIN-2023-40 | https://accessreel.com/article/the-devil-inside-talks-rev-bob-larson-and-melbourne-creepy-premiere/ | 2023-09-26T04:44:33Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.962128 | 1,599 |
The last decade or so has seen the phenomenon of coaching burst onto the professional and personal development space with individuals and companies hiring the services of life coaches and executive coaches on a regular basis. If you are curious about the basics of coaching, interested in coaching, and desire to know more this meet-up is for you.
In this Meetup, you will get to explore & understand,
1) Recap Topic - What is coaching and what is not? What gets commonly mistaken as coaching.
2) New Topic - What’s a Coaching Mindset – Why is it important + How to create it | <urn:uuid:8091ccc8-108a-43dd-a224-0946fbc64227> | CC-MAIN-2023-40 | https://ace.atlassian.com/events/details/atlassian-delhi-gurugram-presents-coaching-mindset-why-how-to-achieve/ | 2023-09-26T04:41:36Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.969135 | 124 |
Hytrol CRB Troughed Conveyor
Troughed Roller Bed Conveyor
The Hytrol CRB Troughed Conveyor is ideally used in scrap handling and recycling operations. The roller bed with deep troughed construction can carry culled or broken glass, cans, wood chips, aluminum, steel, plastic stampings, etc. The CRB is widely used in recycling operations as an environmental conveyor.
- Bed – Roller bed with 2″ dia. x 12 ga. unplated tread rollers spaced every 6″, or 12″ mounted in 10 ga. painted formed steel channel frame with 12 ga. painted side guards extending 8-1/2″ above the belt. Sections bolt together with splice plates
- Rollers – 2″ dia. x 12 ga. unplated rollers spaced every 6″
- Overall Frame Widths: 16″, 18″, 20″, 22″, 24″, 28″ & 34″
- End Drive (standard)
- Motor – 1 HP standard-2 HP max.
- Adjustable Floor Supports Available
- CRB Conveyor capacity – Maximum load per linear ft. of conveyor; 25 lbs., not to exceed rated capacities.
You may also be interested in …
Hytrol RB Conveyor – Medium Duty Roller Bed Conveyors
Hytrol’s RB Conveyor is specifically designed for applications where you need to move heavier loads. The roller bed reduces resistance and belt friction and allows for greater load capacity. The RB Conveyor is suited well for these applications: Assembly line, inspection and packing operations.
For more information and specifications go to Hytrol RB Conveyors. | <urn:uuid:6351f6eb-064c-4642-b8de-5205d0cb5d42> | CC-MAIN-2023-40 | https://acgconveyors.com/partners/hytrol/belt-conveyors/hytrol-crb-conveyor/ | 2023-09-26T06:01:59Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.833179 | 359 |
THE PTP 700
Tactical Microwave Line-of-Site (MLoS) Connectivity Kit provides long-range wireless broadband connectivity in point-to-point and point-to-multipoint topologies up to 250 km. Proven globally in multiple combat and expeditionary operations, the PTP 700 delivers up to 450 Mbps and is the most spectrally efficient radio with the lowest total cost of ownership (TCO) available on the market today.
The PTP 700 MLoS Connectivity Kit (CK) is:
- The most broadly deployed, battlefield optimized, COTS+ (Commercial-off-the-shelf + MILSPEC), turnkey tactical radio system.
- Currently deployed in support of multiple Federal Agency and Department of Defense Programs of Record (PORs).
- The most highly reliable in the industry, offering agencies maximum value and affordability compared to any other system.
- Simple to install, operate, and maintain. It can be quickly deployed by a two-person team in 30 minutes.
- No tools required | <urn:uuid:22db1807-dd2d-4002-8471-4feb0611fe9c> | CC-MAIN-2023-40 | https://acgsys.com/product/ptp-700-wireless-broadband-solution-with-fips-140-2-mil-std-810g-standards/ | 2023-09-26T06:20:32Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.859884 | 218 |
Building on the success of its popular Wild West Chronicles, INSP hopes to make lightning strike twice with Into the Wild Frontier, another ambitious mix of drama and documentary designed to tell the true stories of American legends.
The new eight-episode series, which premieres at 8 pm ET Thursday, Feb. 17, focuses on the intrepid explorers and rugged mountain men who, as America expanded westward during the early days of this country, risked their lives to blaze new trails into the wild frontier. Daniel Boone, Lewis and Clark, John Colter, Tom Fitzpatrick (pictured above), Jim Bridger, Jedediah Smith, Jim Beckwourth and Kit Carson are the heroes of this weekly docudrama, which details their epic tales of adventure and survival.
“As our ratings demonstrate,” INSP executive vice-president of production Doug Butts explained in a prepared statement, “INSP viewers love action, adventure and exploration. Consequently, we’ve made it a priority to produce compelling original content that both entertains and informs. Into the Wild Frontier is a great example of that type of multi-dimensional programming. The series features riveting stories from some of America’s first pioneers – most of whom braved incredible dangers and extremely harsh conditions while exploring America’s Western frontier. Each episode combines substantial research with carefully crafted storytelling, and the result is an action-packed drama that we are confident our audiences will enjoy.” | <urn:uuid:59ae8e9f-6857-4e44-aa2f-68f8c7f4e4c2> | CC-MAIN-2023-40 | https://acinetvreview.com/into-the-wild-frontier-2022-tv-series/ | 2023-09-26T05:51:54Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.913161 | 299 |
In this week’s episode of A Handwoven Experience, I am chatting all about table looms. These adorable little gems are a perfect place to begin if you want to try your hand at weaving. They don’t cost much and don’t require dedicated floor space. Check out the video to hear more about the amazing table loom!
Show Notes –
Table Loom – A table loom is a smaller version of the traditional floor loom that sits on a table. It is portable and reasonably priced. And the biggest benefit is that you can do nearly everything a floor loom can do, just in a tinier format. If you missed it, back in episode 4, I did a tour of the floor loom for comparison. Take a look here!
Schacht Spindle Company – Based out of Colorado, this loom company is my favorite. Both my floor loom and my table loom are Schacht looms. For me, they are the most comfortable and durable looms around. You can peruse their selection of table looms right here.
Learn More –
If you would like to learn more about what you can do with weaving, click here for a free Weaving Pattern Guide! Enjoy! | <urn:uuid:94b90f73-effc-43c4-ad4f-b704ba682be5> | CC-MAIN-2023-40 | https://actoncreative.net/2020/08/12/all-about-table-looms/ | 2023-09-26T05:57:02Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.926358 | 253 |
Direct View / VIP Passenger Cabin Surveillance Solution
The AD Aerospace VIP Passenger Cabin Surveillance Solution or “Direct View” is comprised of a FV-0477 covert HD-SDI video camera (it is a 720p HD-SDI bullet camera externally controllable via RS485), together with an FV-0877 HD monitor. The resulting Camera System is used as a means to comply with CFR 25.785 requirements, designed to provide visibility of a minimum of 50% of passengers in premium class zone to seated cabin crew during Taxi, Take Off and Landing.
The Camera System comprises:
- 720p HD-SDI covert bullet video camera externally controllable via RS485,
- A 2.1mm Pinhole Lens,
- 9″ HD LCD monitor which provides real time and acceptable viewing under most lighting conditions
Recently this Direct View VIP passenger cabin surveillance system was adopted where a customer had a requirement to reconfigure the premium cabin of their Boeing 777 fleet to include new monuments which resulted in areas of the cabin that were not visible to cabin crew during taxi, take-off and landing phases of flight. A solution was required to restore visibility of these obscured areas during these crucial stages of flight so that the cabin crew would be able to ensure that all passengers were seated, as is mandated at these times. Due to the internal passenger cabin configuration, two cameras and two monitors were proposed, with the cameras being mounted in the appropriate bulkhead locations so as to provide the required field of view, and the monitors being located so as to be visible from the forward cabin crew seats.
The FV-0477 HD Camera operates down to very low light levels without the need for supplementary infra-red illumination and it is designed to be covert so as not to be intrusive or easily visible to passengers in premium cabins. The camera transmits an HD-SDI video signal to the FV-0877 HD Monitor, and, in the above use case, these two units were designed to be installed together on the Boeing 777 aircraft to assist in providing compliance with 14 CFR 25.785, with the result that the system was designed to provide seated cabin crew with visibility of at least 50% of the passengers in a premium class cabin zone during taxi, take-off and landing phases.
Want to discuss our products?
Click the button below to contact us today.Contact Us | <urn:uuid:966ac3cb-a23c-4750-b3b8-8f78c0ea6ff1> | CC-MAIN-2023-40 | https://ad-aero.com/systems/direct-view/ | 2023-09-26T06:17:49Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.959853 | 487 |
Objective: To study the outcome in children with brain tumours diagnosed in the first year of life, we followed up 27 consecutive children who were diagnosed between 1980 and 2005 in a single institution.
Methods: Tumour control and neurological, endocrine and cognitive complications and their impact on behavioural and emotional adjustment and health-related quality of life (HRQoL) were comprehensively assessed in 11 survivors (mean follow-up time 12.3 years).
Results: Persistent neurological complications occurred in 9/11 patients, endocrine and growth complications in 4/11, and cognitive deficits leading to school problems/impaired choice of occupation in 8/10. Behavioural and psychological adjustment problems were reported by 4/6 patients and 7/10 parents. HRQoL as rated by patients and their parents was considerably lower than that of healthy controls. In comparison with healthy controls, social functioning was rated by the patients and the parents as the QoL dimension most affected. HRQoL was lowest for patients with high-grade tumour histology and more intense therapy.
Conclusion: Long-term survivors of brain tumours diagnosed in the first year of life are not only at great risk of neurological and cognitive complications, but also of social isolation thereby substantially decreasing self-rated HRQoL.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways. | <urn:uuid:0bd5fcf9-71b8-49b2-a0bd-0ed6109f1796> | CC-MAIN-2023-40 | https://adc.bmj.com/content/93/7/582.full | 2023-09-26T04:51:41Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.951983 | 340 |
Bringing All the Baggage on First Dates
If you have been single for a long time, you can probably share some bad experiences about a couple of your first dates. Singles who have been divorced or separated have to think about going on first dates again. In reality, people who have had numerous dates rarely have a smooth experience on all of them.
But have you ever thought of what could have gone wrong? Maybe you brought all your baggage on board, and the other person did not get along well with it? Well, there are so many ways to bring your baggage on the first date and end up getting hurt. Here are some things to avoid.
More Work and No Time
Many women who are always busy with work and have no time for dating may be difficult to handle even during the first date. Usually, they are frank to tell you that they are always busy at work or at home taking care of the kid. Likewise, men could be addicted to work or leisure activities, making it difficult for a partner to cope with this even on the first date. It is possible for people to cut ties at this stage if such matters arise.
The Fear of What Your Ex Did
Both men and women who have had a bad relationship are likely to bring up the issue of their fears on their first date after a breakup. What they forget is that this is a new date with a different approach. Both men and women feel that this is a turn-off that should not come up at this time. There is a significant likelihood that this could kill the possibility of a second date and the opportunity to start a relationship.
Finding a partner from one of the reliable online-dating websites like https://ero.date/ sounds easy for most people including those who are older. Indeed, it is as easy as looking at someone’s profile and rating whether you like the person or not. But the truth may come out when it is time to meet in person. Even though both of you may have discussed a number of issues online, you may be surprised that people have more baggage that shows up in person. Therefore, it is crucial to be prepared for anything during the first date.
Leave Your Baggage Behind for the First Date
Fortunately, people can avoid baggage on the first date if they know how. Simply, the best way to avoid any negative topic is to focus on positive ones that will make the evening lively. Jokes and humor are important if you want to make the other person forget negative topics they might have discussed. Whoever invited the other on the date has a responsibility to make it work through discussing relevant topics.
It is not the best idea to bring your baggage on your first date no matter how much it has burdened you. This is not the right time to open up to the other person about your baggage. But with time, when you already know each other and have started dating, you can now share past relationship experiences. | <urn:uuid:ea28e5a1-79e1-4deb-b886-0ade70bce3c1> | CC-MAIN-2023-40 | https://addictedtoallthingspretty.com/bringing-all-the-baggage-on-first-dates/ | 2023-09-26T05:52:52Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.97624 | 604 |
SARFT, MIIT develop 3D TV standards
June 22, 2010
The State Administration of Radio, Film and Television (SARFT) has begun formulating industry standards for 3D TV broadcasting. Seven or eight domestic TV stations have plans to launch stereoscopic channels or programmes, according reports.
The China Electronics Standardisation Institute, an affiliate of the Ministry of Industry and Information Technology, is said to be compiling a glossary of 3D television-related terms and is developing 3D television image quality tests. | <urn:uuid:92ec1b7c-1cf7-425b-9b74-9d7407984a2b> | CC-MAIN-2023-40 | https://advanced-television.com/2010/06/22/sarft-miit-develop-3d-tv-standards/ | 2023-09-26T06:06:57Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.910559 | 106 |
You should have heard entrepreneurs and specialists saying, ‘Content material is king.’ Being one of the essential components that assist in figuring out the success of your web site or social media profiles, this phrase could be very a lot true.
It’s your content material by which you’ll inform your viewers concerning the goal of your web site, promote your services, and encourages them to take motion. This clearly factors out why your content material must be partaking and helpful to your customers.
There’s no level in creating content material that your viewers doesn’t relate to or discover useful. As an alternative of partaking your viewers, such content material solely turns them away and distances you from attaining your objectives.
In case you don’t need that to occur, you must begin creating high quality content material that helps you appeal to related leads and grows your conversions.
For that, you could have a highly effective content material technique that helps you obtain these objectives. On this submit, we’ll talk about some highly effective methods which you could strive for your enterprise.
So let’s get began.
1. Leverage user-generated content material
Person-generated content material (UGC) is without doubt one of the strongest methods to develop your content material creation technique. These are any type of content material that has been created by your customers and made accessible on-line, akin to critiques, weblog posts, images, movies, and social media posts. You should use it to create extra content material with much less effort, acquire extra attain, and interact along with your viewers.
And never simply which you could additionally use them to construct belief and credibility along with your target market. Since any such content material is created immediately by your clients, your viewers finds it simple to belief them. In spite of everything, it’s not any form of sponsored or promotional content material. So it seems extra genuine, and your viewers can resonate with them higher.
2. Create interactive content material
Interactive content material is a wonderful method to interact along with your viewers and create content material that stands out. You should have already seen any such content material popping up in your social media feed. This will embrace quizzes, polls, surveys, and extra. However you may as well use them in your web site. For instance, you’ll be able to gamify your web site to make it extra interactive in your customers.
Any such content material shouldn’t be solely partaking however can even enable you perceive your viewers higher and create content material that’s tailor-made to their pursuits. By creating such content material, you’ll be able to simply enhance your web site engagement, increase your site visitors and enhance your customer’s time in your web site.
So should you haven’t tried it out but, do give it a strive.
3. Make the most of video content material
One other superb content material technique that you simply positively want to make use of is to create video content material.
Video content material is without doubt one of the hottest types of content material as we speak, and it’s an effective way to achieve a wider viewers.
Most companies as we speak are utilizing this technique to hold their audiences engaged. And the outcomes are superb. Nevertheless, simply creating video content material doesn’t assist. You additionally want to make sure that the content material is fascinating.
The explanation why any such content material works is that it’s simple to eat. Folks can merely watch the video and get the data they need with out having to learn by the content material. It’s an exquisite approach of partaking your viewers and convincing them to return again to your web site once more.
4. Make the most of influencer advertising
One other extremely popular content material advertising technique is to leverage influencer advertising. It’s an effective way to develop your content material creation technique and increase your conversions. Influencer advertising is a sort of promoting that focuses on utilizing key leaders to drive a model’s message to the bigger market.
Moderately than advertising on to a big group of customers, a model can work with an influencer to achieve a smaller however extremely engaged viewers of followers.
Influencers could be well-known celebrities, however extra typically, they’re Instagram or YouTube personalities with a big following. They permit manufacturers to faucet right into a pre-existing group of engaged followers who belief the influencer’s opinion.
Using influencers to assist promote your content material might help you attain a bigger viewers and construct belief along with your target market.
Simply guarantee that the influencer you’re employed with is somebody in your area of interest.
So these are a number of highly effective content material methods you may need to check out. We hope you want them. Do tell us within the feedback under. | <urn:uuid:7907b461-b390-49a5-8e18-531c1dd31c73> | CC-MAIN-2023-40 | https://affiliatemarketingbusiness.net/4-highly-effective-content-material-creation-technique-youre-not-utilizing/ | 2023-09-26T05:45:30Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.926404 | 1,020 |
Media in the ever shifting business landscape / Media: In your business interest
The Outlook: Banking on and investing to win with Africa
Innovations in education delivery and corporate learning
Smart projects meet smart money: How to scale your success in Africa. The state of tech in Africa and the investment opportunities
The state of healthcare in Africa: Opportunities in building a healthcare system that truly cares.
Citizens conversation on Africa’s recovery and growth
Feeding Africa and the world. | <urn:uuid:4c62ba64-3325-4e6e-87bf-bfe28e583ce4> | CC-MAIN-2023-40 | https://africabusinessconvention.com/wcs-type/abc-conference-day-2/ | 2023-09-26T06:52:37Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.900504 | 100 |
Blockchain Identity Management Market to Capture a CAGR of 65.6% Between 2022 and 2030 While Touching Approximately USD 6,500 Million by 2030-End – Report by Market Research Future (MRFR)
Securing the Digital Realm: Blockchain Identity Management Unleashed
New York, USA, June 23, 2023 (GLOBE NEWSWIRE) — According to a Comprehensive Research Report by Market Research Future (MRFR),” Blockchain Identity Management Market Information by Component Type, by Provider, by Organization Size, by Vertical, and Region – Forecast till 2030”, Blockchain Identity Management Market could thrive at a rate of 65.6% between 2022 and 2030. The market size will reach around USD 6,500 Million by the end of the year 2030.
Blockchain Identity Management Market Synopsis:
Blockchain Identity Management refers to the use of blockchain technology to manage and authenticate digital identities securely and efficiently. It enables individuals and organizations to have control over their personal information while ensuring privacy, security, and trust in digital transactions. Blockchain-based identity management systems offer decentralized and tamper-resistant solutions that eliminate the need for intermediaries and enhance the protection of sensitive data.
The uses and applications of Blockchain Identity Management are diverse. It finds extensive application in areas such as financial services, healthcare, government, and supply chain management. In financial services, blockchain identity management enhances Know Your Customer (KYC) processes, streamlines customer onboarding, and enables secure and compliant transactions. In healthcare, it enables secure sharing of patient records and ensures the integrity of medical data. Government agencies can utilize blockchain identity management for secure citizen identification and streamlined service delivery. In supply chain management, it enhances traceability and transparency by securely verifying and tracking product origins and authenticity.
Get Free Sample PDF Brochure –
Market Competitive Landscape:
The affluent companies in the Blockchain Identity Management industry include
- Oceaneering International
- Bluefin Robotics Corp
- International Submarine Engineering
- Schilling Robotics LLC
- Saab AB
- Inuktun Services Ltd.
Latest Industry Updates (March 2023):
One recent development in the Blockchain Identity Management market occurred in March 2023 when a leading player introduced a blockchain-based identity verification platform. This platform utilizes smart contracts and cryptography to enable secure and decentralized identity verification. It provides individuals with full control over their personal data and enables them to selectively share information with trusted entities. This development showcases the continuous innovation in blockchain identity management, focusing on improving privacy, security, and user control.
Scope of the Report – Blockchain Identity Management Market:
|Market Size by 2030||USD 6,500 Million|
|CAGR during 2022-2030||65.6%|
|Key Market Opportunities||Government support for digital transformation.|
|Key Market Dynamics||Increasing focus on better security Better data management of customers with secure identity.|
Buy Now Premium Research Report – Get Comprehensive Market Insights.
Market USP Covered:
The market driving factors for the Blockchain Identity Management market are increasing concerns about data privacy and security, growing digitalization and online transactions, and the rise of decentralized applications (DApps). In today’s digital era, individuals and organizations are increasingly concerned about the protection of their personal data. Blockchain identity management offers a robust solution by providing enhanced security, encryption, and user consent mechanisms. Furthermore, the growing number of digital transactions and online services necessitates reliable and efficient identity verification systems, which blockchain technology can provide. Additionally, the rise of decentralized applications and platforms that rely on blockchain technology creates a demand for secure and interoperable identity management solutions
The restraints for Blockchain Identity Management. One major challenge is the lack of standardized regulations and legal frameworks. The regulatory landscape surrounding identity management varies across different jurisdictions, which can hinder the widespread adoption of blockchain-based solutions. Additionally, interoperability issues among different blockchain platforms and identity management systems pose a challenge. Efforts to establish industry standards and frameworks for interoperability are crucial to address these limitations and drive the market growth.
The COVID-19 pandemic has had a mixed impact on the Blockchain Identity Management market. On one hand, the pandemic has highlighted the importance of secure and reliable digital identities for remote work, online services, and contactless transactions. This has accelerated the adoption of blockchain identity management solutions. On the other hand, the economic slowdown and disrupted business operations during the pandemic may have led to budget constraints and reduced investment in technology projects. However, post-COVID, the market is expected to rebound as organizations prioritize digital transformation and invest in robust identity management solutions to address evolving cybersecurity threats.
Browse In-depth Market Research Report (100 Pages, Charts, Tables, Figures) on Blockchain Identity Management Market –
- By Component Type – The component Type in the market includes Software, and Solution
- By Provider – By provider in the segment includes Application, Middleware, and Infrastructure
- By Organization Size – The organization size includes Large Enterprises, and SMEs
- By Vertical – The vertical includes BFSI, Telecom & IT, and Government
North America is at the forefront of the Blockchain Identity Management market due to several factors. The region is home to technologically advanced economies, such as the United States and Canada, which have a strong adoption of blockchain technology across various industries. These economies have a robust ecosystem of blockchain startups and established companies that are driving innovation in the field of identity management. Moreover, North America places significant emphasis on data privacy regulations, with initiatives such as the California Consumer Privacy Act (CCPA) and the Health Insurance Portability and Accountability Act (HIPAA), which have heightened the need for secure and privacy-centric identity management solutions.
Europe closely follows North America in the Blockchain Identity Management market. The region has established itself as a global leader in data protection and privacy with the implementation of the General Data Protection Regulation (GDPR). The GDPR places stringent requirements on the processing and storage of personal data, driving the adoption of secure and privacy-enhancing technologies such as blockchain. European countries, including Germany, France, and the United Kingdom, have been proactive in exploring the potential of blockchain technology for identity management. The European Union’s focus on secure digital identities, as part of its digital transformation initiatives, further contributes to the growth of the market in the region.
Ask for Customization – Get a customized version of the report by submitting a customization request.
Asia Pacific is anticipated to witness significant growth in the Blockchain Identity Management market. Countries like China, Singapore, and South Korea are making substantial investments in blockchain initiatives, recognizing the potential of the technology to transform various industries, including identity management. The region has a large population and a rapidly growing digital economy, which drives the demand for secure and trusted digital identities. Governments in Asia Pacific are actively supporting technology adoption and fostering innovation in blockchain, further fueling the market’s growth. Additionally, the increasing digitalization and the rise of digital services in sectors like finance, healthcare, and e-commerce contribute to the market’s potential in the region.
- Intranet as a Service Market – Intranet as a Service Market Projected to Hit USD 40.74 Billion at a 13.82% by 2030 – According to MRFR
- M2M Communication Market – M2M Communication Market To Hit USD 27.41 Billion at an 8.32% CAGR by 2030 – Report by Market Research Future (MRFR)
- Mobile Biometric Security and Service Market – Mobile Biometric Security and Service Market Worth USD 63.98 Billion at a 27.48 % CAGR by 2030 – Report by Market Research Future (MRFR)
Browse through more Information And Communications Technology Research Reports.
About Market Research Future:
At Market Research Future (MRFR), we enable our customers to unravel the complexity of various industries through our Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services.
MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, technologies, applications, end users, and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions.
Market Research Future (Part of Wantstats Research and Media Private Limited)
99 Hudson Street, 5Th Floor
New York, NY 10013
United States of America
+1 628 258 0071 (US)
+44 2035 002 764 (UK)
Email: [email protected]
Follow Us: LinkedIn | Twitter
Disclaimer: The above press release comes to you under an arrangement with GlobeNewswire. AfternoonHeadlines.com takes no editorial responsibility for the same. | <urn:uuid:d6d3363a-bf9b-4535-8930-31ab55e64384> | CC-MAIN-2023-40 | https://afternoonheadlines.com/blockchain-identity-management-market-to-capture-a-cagr-of-65-6-between-2022-and-2030-while-touching-approximately-usd-6500-million-by-2030-end-report-by-market-research-future-mrfr-54291/ | 2023-09-26T05:18:42Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.881828 | 1,952 |
Update on the Company’s management plans, and M&A Cooperation Framework Agreement signed between the Company’s subsidiary, Liaoning Kangbaier Biotechnology Development Co., Ltd. and the Anshan Tanbao Technology Co., Ltd.
Panjin City, Liaoning Province, April 20, 2023 (GLOBE NEWSWIRE) — Kangbaier Biotechnology Development Co., Ltd. (“Kangbaier”), a wholly-owned subsidiary of Bitmis Corp. (“the Company”) (OTC: BIMT), has made a series of development plans including asset expansion, industrial upgrading, brand strengthening, channel expansion, and chain business under the management’s planning:
I. In the Panjin Food Industry Circular Economy Demonstration Park, we will build the “Kangbaier International Health Industrial Park”, which integrates R&D, production, logistics, office work and health care. We are implementing the relevant procedures and strive to put into construction in June 2023, and complete the first phase of construction before the end of the year.
II. Adhering to the strategic positioning as a product service providers for integrated transformation of agricultural high-tech achievements, we will steadily improve product development advantages, product quality advantages, cultural innovation advantages, and greatly improve the brand exposure and popularity of Kangbaier through Q&A, post bar, library, micro-blog, self-media, news sources, videos and other channels.
III. On the basis of Baijiakang Healthy Lifestyle Supermarket, we will expand various forms of chain business through direct marketing, alliance, mixed operation and other means to construct multi-type industrial layout, and further realize multi-terminal coverage on the supply chain commodities of Kangbaier from point to area.
IV. From the northeast to the whole country, we will unite the high-quality enterprises in the field of large agriculture and health through industrial merger and acquisition, and use capital to empower the rapid development of enterprises.
On March 18, 2023, the M&A Cooperation Framework Agreement was signed between the Liaoning Kangbaier Biotechnology Development Co., Ltd. and the Anshan Tanbao Technology Co., Ltd. (“Tanbao Technology”). Founded in 2009, Tanbao Technology is an enterprise specializing in the development of healthy and environmental protection series products with agricultural straw as the main raw material. Kangbaier has cooperated with Tanbao Technology for many years. And they are interconnected and mutually empowered in terms of sales channels of the series products between carotene and negative oxygen ions. The M&A Cooperation Framework Agreement makes their cooperation to a new level and also marks the official opening of the strategic policy for integrating the upstream and downstream industrial chains through M&A and helping the rapid development of the enterprise. The M&A of high-quality enterprises not only meet its development needs for the capital market of Kangbaier, but also promote its construction for a converged supply chain to form a multi-form industrial layout, which is of great significance to the high-quality development of Kangbaier. The Company is currently conducting preliminary due diligence and other related works on Tanbao Technology. | <urn:uuid:0c282b43-a6c8-49d3-ab0e-9b1d73f4dc18> | CC-MAIN-2023-40 | https://afternoonheadlines.com/update-on-the-companys-management-plans-and-ma-cooperation-framework-agreement-signed-between-the-companys-subsidiary-liaoning-kangbaier-biotechnology-development-co-ltd-and-th-47255/ | 2023-09-26T06:26:57Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.921473 | 669 |
- You cannot add "Racing Biker Full Gloves For Motorcycle Riders" to the cart because the product is out of stock.
Motorcycle Goggles With Dust MASK
Contact # 0322-6634447
Cash On Delivery Also Available All Over In Pakistan.
5-A, Guldasht Town, Zarar Shaheed Road,Lahore
3 in stock | <urn:uuid:20a380c0-adae-4fe9-84f5-96cbb1197b27> | CC-MAIN-2023-40 | https://afzaltraders.com/product/motorcycle-goggles-dust-mask/?add-to-cart=3270 | 2023-09-26T05:13:52Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.743408 | 87 |
EM | Ricardo BofillCopyright: © RBTA
"Architecture is a timeless art that responds to the permanent need of man to build space."
(Ricardo Bofill, Buildings and Projects 1960-1985, New York 1988)
In this block seminar we will explore the equally peculiar and fascinating oeuvre of recently deceased Catalan architect Ricardo Bofill and his "Taller de Arquitectura", focusing on his works created in the 1960s to the 1980s.
In the first part of the seminar, we will focus on his early work in Barcelona of the 1960s, where he created buildings of surprising timelessness, including brick-faced apartment buildings such as those in the Carrers de Bach and de Nicaragua. We will then look at the large, fractal-like housing complexes of the 1970s such as the Edificio Xanadú, La Muralla Roja and Walden 7, which still bear witness today to how Bofill recurrently sought to combine the urban with traditional motifs of vernacular architecture and how he thereby found an absolutely independent architectural language that gave expression to his social utopian ideas. In the third part of the seminar, we will explore his neo-Mannerist ensembles in France in the 1980s, his famous spatial structures, sometimes used as film sets, such as the Espaces d'Abraxas, which quote millennia-old traditional architectural elements and principles, but then quite often invert them, sometimes even dissolve them.
We will therefore examine his oeuvre – if one wants to attempt a categorization at all – which is most likely to be located between critical regionalism and postmodernism during the decades mentioned, on the basis of his clearly identifiable creative phases in chronological order, although it will be above all the (visible and invisible) thresholds and transitions, indeed the mediators between them, that we would like to identify and learn to understand.
Elective Module | Block seminar
M.Sc. | all semesters
October 17, 2022 | Kick-Off
January 25 to 27, 2023 | Block seminar with presentations
February 27, 2023 | Submissions
Ricardo Bofill . Selected Project Examples
(pdf: 6930 kb)
In the document above you can have a look at a short selection of project examples of Ricardo Bofill's "Taller de Arquitectura" that we will analyze in the scope of the seminar. | <urn:uuid:07844faf-92ea-4fb3-ab24-dc7d98341702> | CC-MAIN-2023-40 | https://ages.rwth-aachen.de/cms/AGES/Studium/Lehre-WiSe-2022-23/~szspt/WA-Ricardo-Bofill/?lidx=1 | 2023-09-26T06:29:59Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.946146 | 522 |
5 Common Gold Investor Mistakes and How to Avoid Them
When looking to diversify your investments, one of the decisions you’ll have to make is where to invest your money. One of the most popular methods is investing in gold.
In the United States, approximately 800 tons of gold are produced every year. As a result, it’s super easy to invest in gold due to the abundance of the material. With the market valuation at an all-time high, it’s an opportune time to invest.
But making the jump to investing in gold isn’t easy. Below, we’ve outlined common gold investor mistakes and how to avoid them. Read on to learn more.
1. Investing Without Proper Research
With the vast amount of information available online, there’s really no excuse for not researching gold before investing. Not doing your research can lead to buying gold at an inflated price or falling for scams.
To avoid these mistakes, it’s important to research the gold market and know the current price of gold before making any investment. You’ll also be more likely to find the best investment opportunities.
2. Failing to Diversify
While gold can be a great investment, it shouldn’t be the only thing you have invested in. Diversifying your portfolio will help reduce your overall risk and give you a better chance of achieving your financial goals.
If you are a new gold investor and love rare coins for their beauty, buying gold coins is a great idea. You can purchase both silver and gold coins directly from Lear Capital coins.
This is often the result of buying gold from a less-than-reputable source. These sources typically sell gold at a much higher price than what it is actually worth. To avoid paying too much for gold, do your research and only buy from a reputable dealer.
4. Not Storing Your Gold Properly
Gold is a valuable asset, and it is important to keep it in a safe place where it will not be damaged or stolen. Many people store their gold in a safe deposit box at a bank, but this is not always the best option. If the bank is burglarized or experiences a natural disaster, your gold could be lost or damaged.
It is important to have a backup plan for storing your gold, such as a home safe or a storage facility that specializes in gold storage.
5. Buying Gold at the Wrong Time
The value of gold fluctuates based on economic conditions, making it a volatile investment. Many investors choose to buy gold when the economy is weak in hopes of making a profit when the economy recovers. However, this is often a mistake.
Investors who buy gold at the wrong time often end up selling at a loss. To avoid this mistake, investors should only buy gold when they are prepared to hold it for the long term. The best gold investment strategy is to consider a long-term hold.
How to Avoid Common Gold Investor Mistakes?
One of the most common gold investor mistakes make is failing to do their homework before investing. Gold is a complex investment, and it is important to understand the risks and rewards before putting any money into it. It is important to educate yourself on the different types of gold investments and understand the risks involved before making any decisions.
Many gold investors make common mistakes that can be avoided with a little bit of knowledge and research. By doing your research before investing, you can help protect yourself from making costly mistakes.
If you find this article helpful, check out our blog for more informative content. | <urn:uuid:fac54823-c335-499e-997d-0fa86d4b7c24> | CC-MAIN-2023-40 | https://aguyblog.com/5-common-gold-investor-mistakes-and-how-to-avoid-them/ | 2023-09-26T05:22:30Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.948215 | 745 |
“See Why Nigerian Music Industry Needs A Peter & Paul Resurrection”.
Peter and Paul Okoye, are a very popular Nigerian singer and dancer, a stage vibrant duo; identical twin brothers known as P-SQuare. The recent defunct music duo that truly entertain, leave every fan thrilled, filled and overly excited with their electrifying performances. Their split in 2017 for relationship feud, to run separate careers and never come back after series of fan persuasion is very strong ill sign written boldly on the wall of a tied fate, “things have fallen apart for the duo”, accompanied a head slowly shaking from left to right saying, “Oh no, Oh no!”. Maybe that could be their late Mother who’ve been watching them from abyss and wishing to be with her super talented boys 30mins, after leaving the land of the dead. Perhaps, they might understand less the whole situation if they were given a day to see the strong grief in this illustration.
Mr P and Rudeboy, now separately lack that strong bond for an edge amongst contemporaries and impactful records as defunct PSquare. Talk less of gaining chances to express their lovely electrifying performances which they’ve always shared since high school now robbed to separateness; they are slowly fading away and that’s not why Peter and Paul have been created by God, as unique pairs to conglomerate artistic distinction.
Maybe their going separate cause, would not be fan comprehension or could a supernatural manipulation beyond human, manhandle this cause? Because I really feel they both are leaving behind a higher purpose to fulfill with artistry, rather they are settling on for mere conflict and separation. No records together, nor have they been seen together for music videos, and really nothing solid have ever come from them running separate cause. Of course, they can get differences as pairs but this kind, is over reactive and it’s severely affecting their both growth. I feel it’s a supernatural force manipulated to avoid them reaching full potentials as outstanding superstars.
The popular Nigerian acts, Peter and Paul; have really blessed and improved the quality of Nigerian cultural audience from Hip-hop, Dance hall to pure R&B records which struck in us still moments at mid 2000s from their classic, “Miss You Die”, “Game Over”, “Roll It”, “Alingo”, “Do Me” and major bangers which they delivered, left us stocked with their memories till date. They were really wonderful together. The duo is irreplaceable, and they practically engaged Nigerians in club way back, especially with their divine talents designed to work a perfect route for a distinctive career to glow in one. Well, the duo also assisted in building the cross over bridge in Nigerian music industry way back, which have seen the successful crossover of various acts till date. However, they have been literally left behind since their split is mysterious and they seem reckless about changing the situation. No position or true essence after the split, nor a genuine impact since their solo careers took off till date.
Perhaps, they have no plans for resurrection either. But obviously, Peter and Paul is derailing and going the wrong direction; only if their lovely late Mother, Mrs. Josephine Okoye, was alive to render the duo a better advice as she would be in a better position to reunite, bless and witness the tremendous increase of her progeny, Peter and Paul. Of course they’ve made certified hallmark in Nigerian music industry. PSQuare, settling for any separation that leads a route headed for no record release together, isn’t worth sacrificing no matter the cause or difference they might share. We still strongly believe in you two, if you both no longer; as you have unreleased testaments to still unveil us. You both once settled together, helped the industry thrive and now should be part of that force rendering pure, and real fine Nigerian R&B and Hip-hop taste, plus your outstanding Dance hall suction. For once, fly and aim higher together sitting inside the same craft, set the pace headed with unstoppable wave and distinction, attaching global cultural expansion away from Afro-beats. Please, don’t make us feel the indisputable PSQuare have nothing left to offer; but deep down destiny has tied you both together, forever. We need a Peter & Paul resurrection one more time, the glow is necessary so we can see the industry through a new shape that lies off from popular Afro-beats culture. You guys being together is a live long experience the world still awaits, longing for your transitions together from way back and deserve to capture you both electrifying moments dated from high school once more… | <urn:uuid:31685191-4d73-4ebe-ae66-df3a5207ae36> | CC-MAIN-2023-40 | https://agwumakingsley.medium.com/see-why-nigerian-music-industry-needs-a-peter-paul-resurrection-2f854776dae7?source=user_profile---------8---------------------------- | 2023-09-26T04:45:15Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.957703 | 977 |
The 2023 NFL Draft is quickly approaching, with rumors about prospects flying all over. Prospects are moving up and down draft boards, and it seems like one player who is gaining some steam is Boston College wide receiver Zay Flowers.
According to NFL insider Jeremy Fowler, Flowers’ stock is “surging.”
“Also in pass-catching buzz, don’t be shocked if Boston College’s Zay Flowers is the first wide receiver off the board,” Fowler wrote. “His stock is surging.”
Flowers made some headlines back in February after he revealed an impressive body transformation. That undoubtedly is one of the reasons why his stock is rising.
— Nick Hicks (@PER4ORM) February 27, 2023
Over the course of his career at Boston College, the Florida native caught 200 passes for 3,056 yards and 29 touchdowns. He was productive in every single one of his four years with the Eagles.
The 22-year-old has already been linked to plenty of teams, including the Dallas Cowboys, Las Vegas Raiders and New England Patriots. All three of those teams have picks in the first round, which is when Flowers is expected to be selected.
— Tom Pelissero (@TomPelissero) April 4, 2023
BC WR Zay Flowers landed in Boston at 6 a.m. from an overnight Vegas flight and went straight to the #Patriots facility to spend the day learning the offense with Bill O’Brien on his visit, per source. New England has the No. 14 pick, three weeks from today.
— Tom Pelissero (@TomPelissero) April 6, 2023
Flowers seems to make a lot of sense for the Patriots, who have a strong need for a wideout after the departure of Jakobi Meyers, who signed with the Raiders.
Some of Flowers’ strengths are his shiftiness and ability to get open downfield consistently.
“Slot target who plays with unbridled energy and immense confidence,” wrote NFL.com’s Lance Zierlein in an evaluation of Flowers. “Flowers is slightly built but can side-step press and fly into action with above-average acceleration and an attacking demeanor. Flowers has a tendency to rush his routes, but his ability to play with speed and move with athleticism makes him hard to read for defenders. His ball skills will shine brightly at times, but frustrating drops come with the package. Flowers has the skill set to become a valuable playmaker as a pro.”
Flowers has been consistently mentioned as one of the top receivers available in the 2023 NFL Draft, and the buzz is showing no signs of slowing down.
The future is really bright for Flowers, and it’ll be interesting to see where he ends up landing. When all is said and done, he could easily end up being one of the best players from this draft class.
The 2023 draft is slated to get started on April 27 and will run through April 29. Flowers has reportedly accepted an invitation to the draft and will attend. | <urn:uuid:05eb4a8f-f381-4518-bbe0-2d429dc6157e> | CC-MAIN-2023-40 | https://ahnfiredigital.com/nfl/nfl-insider-says-1st-wr-drafted-could-be-boston-colleges-zay-flowers-as-his-stock-is-surging/ | 2023-09-26T06:05:20Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.976709 | 646 |
Each January 1st, the Town of North Beach holds a Polar Bear Plunge, where adventurous people of all ages run into the Chesapeake Bay for a few minutes. This is a fund raising event for Charity as well as a fun event for the town. The Calvert County Ladies of Charity organization was the recipient of the proceeds from the Polar Bear Plunge in North Beach, MD January 1, 2020.
The Ladies were asked to man the tables where all “plungers” had to sign a waiver before going to the registration desk to sign in. We had gold hats made to identify the LOC members.
The Town of North Beach also gave the LOC the exclusive right to sell snacks at the event. We manned the Papa John’s pizza wagon and were allowed to keep the profits.
The Ladies are great bakers and we also had a baked goods table with lots of goodies for sale. Our very own “crab” lady mingled with the plungers and spectators as well soliciting do-nations. | <urn:uuid:7344881e-5f6e-4978-b870-8bc1d9b112f5> | CC-MAIN-2023-40 | https://aic.ladiesofcharity.us/2020/07/09/annual-new-years-polar-bear-plunge-in-north-beach-md-benefits-loc/ | 2023-09-26T06:26:50Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.981269 | 221 |
With fractional ownership investing, you own a portion of a property yet still receive the same advantages as if you had bought the entire asset. You get to enjoy all the benefits of real estate investing without worrying about expenses, property maintenance, or anything related.
Fractional ownership investing is becoming a more popular way to buy property in the real estate market. It allows investors to buy a percentage stake in various properties, with others splitting the cost and ownership of the asset. Once in place, fractional real estate is significantly cheaper than purchasing an entire property. It can also sometimes generate a better return for its owners than buying a whole property outright.
Fractional real estate is a low-risk, high-growth investment that offers many advantages to investors and non-investors. It allows you to buy a part of a property instead of the entire asset, which means you can become an owner without putting large amounts of cash down. A fractional real estate investor can also choose from various properties in different locations, diversifying their portfolio even more to achieve better returns.
A business purchases a piece of property. Although it is primarily commercial real estate, it could also be residential. The company divides the property’s price into fractional shares, which they then market to investors.
Anyone who invests receives cash flow from the rent paid on the asset. As an investor, it’s important to note if the property is already producing income or is still under development.
Pros & Cons of Fractional Ownership Investing
A fractional ownership agreement is a relatively new investment in real estate. Not many people realize all of the benefits and drawbacks of fractional ownership. While there are some fantastic advantages to fractional ownership, there are a few things you need to be aware of before investing. This guide will highlight some of the most important pros and cons before becoming a fractional real estate investor.
Lower Barrier to Entry
Across all of real estate, the fractional ownership investing model represents a great way to start investing with relatively small sums of money. As an investor, this means you can enjoy returns on properties in markets that may not have been reachable otherwise due to the size of the original investment needed. And on top of the initial investment required being smaller, the returns occur more quickly since you will also earn equity in the property as value grows.
Investing in rental properties with other people’s money can help you access assets, especially if you don’t have the necessary down payment. With multiple owners sharing in costs and profits, a high-end condo, resort, residence club, or vacation home becomes attainable without years of saving (and missing out on opportunity costs). Plus, these rental properties are unlikely to sit empty for too long since they are in high demand, increasing your potential rental income.
As a fractional property owner, you can enjoy the benefits of passive income and building wealth. Because the value of each person’s share increases as the property appreciates, you also have the potential for cash flow from tenants if the property rents.
And with a management company handling both the purchase and the financing of the real estate investment, you can rely on their expertise, saving you a lot of time and resources on research and other fees that go along with real estate investing.
Fractional ownership is a great way to share the cost of a vacation home without paying for everything yourself. Fractional ownership is often understood as a timeshare model, but there are critical differences between these two. When you buy a fractional share in a property, you receive a deed for your equity portion, which means you have the right to sell, gift, or inherit the property and place it in a trust.
Share the Cost of Maintenance and Taxes
Shared ownership means that you and other co-investors own the property. Shared expenses during this stage, like taxes, insurance, and HOA fees, are tax-deductible. You’re also responsible for repairs to the property. Whether you sell your home as a fractional or complete owner, your share of the proceeds will be subject to capital gains tax.
Easier to sell than a wholly-owned property
Fractional real estate is a cheaper way to invest in property. You can secure your piece of it for a fraction of the price of buying an entire property. This means that even if someone else buys part or all of your share, you still retain an investment in that property. When you eventually sell your stake, you have to pull out from the investment, allowing your shares to be re-listed and sold again.
Easier to diversify
With fractional ownership, you can diversify your real estate investing. For example, shared ownership allows you to participate in vacation home ownership while investing in commercial and residential real estate while simultaneously making your mortgage payments. Since all your resources aren’t tied up in a single large investment, you can spread your resources out among different types of real estate or set your sights on a single location or neighborhood in the same city. You can specialize in a single class or area or keep diversifying and taking advantage of market ups and downs variations.
With full ownership of a property, an investor has a complete say in all decisions concerning the property. However, with fractional ownership, all owners have a say in the management of the property, including maintenance, repairs, and decor. This can sometimes cause disagreements. Sales also have to be approved by all ownership partners. Make sure to review all real estate syndication contracts with a professional.
Fractional real estate can be a great way to build wealth with real estate without having to take on the burden of ownership. You can enjoy the benefits of a rental property through fractional ownership without worrying about maintenance or upkeep. And while there can be additional costs associated with managing this type of investment, it’s far less than owning a home or condo outright. If you want to consider investing in real estate but don’t want the hassle and risk of dealing with mortgages, cleaning fees, and other expenses, then fractional real estate may be for you.
Buying a fraction of a property is a great way to get into real estate investing, and the benefits are many. If, after reading through this fractional ownership guide, you decide this model is suitable for you, starting is as easy as signing up on a platform such as Fundrise, Crowdstreet, or Arrived, selecting a property from their portfolio, and making your first investment. | <urn:uuid:225cc328-e4e4-421b-81b5-9202ae45cbb6> | CC-MAIN-2023-40 | https://ajoything.com/blog/wealth/fractional-ownership-investing/ | 2023-09-26T06:19:02Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.959425 | 1,358 |
Vacation rentals in Leland Lake
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Leland Lake
Guests agree: these stays are highly rated for location, cleanliness, and more.
Cabin in Brinnon
McDonald Cove Cabin
The perfect retreat on beautiful Hood Canal. Rustic cabin is well-maintained and super cozy. Open concept for easy entertaining with glorious views of the water. Main floor bedroom with Queen bed plus open loft with Queen bed. The cabin has one bathroom opposite the downstairs bedroom. Great outdoor living with two decks; front deck facing the waterfront. Use stairs to access the beach and boat house which houses two single kayaks, one double kayak, life jackets, and beach chairs for guest use.
$253 per night
Cabin in Port Townsend
Breathtaking Beach Cabin With Spectacular Bay View
Experience healing and peace with the sound of gentle waves on Discovery Bay. Our cabin was built in 1939 by our grandfather who was an early businessman in Port Townsend. He wisely recognized for decades to come this would be a prized place of rest, enjoyed by 5 generations. Our two kayaks for beginners and new paddle board are available for rent. Explore the unbelievable beauty of the Olympic National Park just a few miles away featuring hiking to rainforests, glaciers, and mountain lakes.
$147 per night
Guesthouse in Quilcene
Owl's Nest Guest House
Adorable, and neat as a pin, this "Greenpod" guest house is tucked away on 64 acres of mixed forest and meadows in the foothills of the Olympic Mountains. Hiking trails, parks, waterfalls, shellfishing, boat ramps, and swimming beaches are just minutes away. Come experience the best of the Pacific Northwest! This sweet guest house sleeps two and has a queen bedroom, a living room with mountain views, a full sized bathroom with step-in shower, and modern kitchen. Now with AC and free wifi!!!
$130 per night
Vacation rentals for every style
Get the amount of space that is right for you | <urn:uuid:2dad3ef5-e1b9-4252-aa92-214969901cd6> | CC-MAIN-2023-40 | https://akamai-dev.airbnb.com/leland-lake-wa/stays | 2023-09-26T07:26:11Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.935816 | 445 |
For added content and learning live most of the time then choose the Ultimate package instead for more value.
Videos with Messages plus Consultations and Meetings also Webinars
President, Hernandez MasterMind
I continue to be Passionate about helping Entrepreneurs with a Proven Solution, and Employees with Starting a Business; in the effort to provide them Mastering Experiences.
I personally have used Alan Hernandez for my franchises since 2009. Alan is smart, fast on his feet; and very dependable.
Personal Trainer, Elite Strength & Fitness | <urn:uuid:06abb0c8-9aa9-45dd-b200-d327f1f25ad1> | CC-MAIN-2023-40 | https://alainhernandez.com/checkout-for-mastering-experiences-ultimate-plan/ | 2023-09-26T04:58:55Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.878258 | 116 |
Audio Series to Learn Experiences On-the-Go with any Device
and Live Presentations for One-on-One Coaching that is Powered with Interaction.
You will have 2 Hours to take advantage of this offer, bookmark this page or close it is not going to matter; if you come back before the timer runs out you have a chance to lock the price listed.
DISCLAIMER: After the time expires you will never see this page or offer again. Instead, you will always be redirected to the regular sales page; act now!
Take advantage of the On-the-Go Learning that is a Audio Version of all the videos.
As a subscriber of the Startup Knowledge Learning, you now have the opportunity to upgrade your education to an audio series, which basically what you get is a transcribed version of all the videos.
Audio for Mastered Learning
I have learned so much from alain about how to strategize in marketing my business using google ads.
Protec Garage Door | <urn:uuid:e40374d4-1708-4aa0-9270-4d9d90addcda> | CC-MAIN-2023-40 | https://alainhernandez.com/funnel/startup-knowledge-learning/audio/ | 2023-09-26T05:14:13Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.916227 | 215 |
The fastest way is to buy Pundi X with a credit card, but you will be charged higher fees. Europeans can use BitPanda to buy bitcoins or ethereum with Skrill. Ethereum or BTC can then be converted into Pundi X on Binance. Yes, you can do that easily by using Binance to exchange bitcoins for Pundi X.
XWallet is built to provide a secure system that makes it easy to manage multiple digital assets like Bitcoin, ETH, DAI, NPXS, BNB, XEM, and many other tokens on the go. Recently we have integrated the Telegram chat app and added the “Crypto Gift” feature to allow users to send and receive digital assets easily via Telegram chat. Pundi X is legal in India, and users can engage in buying and selling this on the exchanges.
Receive Pundi X from anyone instanteniously through your web browser, mobile phone or desktop app. Guarda allows you to easily buy Pundi X online and send it to anyone and anywhere with their Pundi X address. Instantly exchange Pundi X with the best NPXS exchange rates. We offer many trading pairs for Pundi X trading through our exchange partners. Swap NPXS for Bitcoin or any other asset from our rich crypto selection. 73% of millionaires have already invested in cryptocurrencies or will invest in them before the year 2022, and NPXS may be among them.
If you prefer, you can also use an online wallet to keep your holdings safe on the internet. You will be asked to through the process of confirming your e-mail address as well as verifying your identity. It would be best if you went through that procedure at once to avoid any issues before putting money on the platform. Coinbase will ask for personal information such as your home phone number, your address, and proof of your identity using an official document such as a passport or a driver’s license. You’ve purchased Pundi X using USD with the help of another crypto exchange. All you need to do is click on the “Prices” option in the top menu bar and you’ll see a list of all the supported cryptocurrencies on Coinbase. Once you are at their website you’ll need to enter your email address in the get started box.
How To Buy Pundi X Npxs From Above
MAKE SURE to use your real name as Coinbase will use this for account verification. 2) Next enter your email address in the get started box. Please MAKE SURE that the email address you enter is one you have access to and is your most secure email as this is how you will always sign in to your Coinbase account. Although Coinbase has both iOS and Android apps, I have found the easiest way to setup your exchange account with them is to use their website.
- PundiX grants awards for the promotion of purchases by XPOS to registered dealers.
- But don’t worry, it’s basically simpler than making a bank transfer.
- Using this registration link, you get a $200 bonus on your first deposit equivalent to 0.017+ BTC.
- The Pundi X price page is part of Crypto.com Price Index that features price history, price ticker, market cap and live charts for the top cryptocurrencies.
- Buy Pundi X safely and easily at one of Europe’s leading exchanges.
- We send a brief email usually once every two weeks with news, giveaways, and updates.
Instantly exchange Pundi X at the best NPXS exchange rate. Kriptomat is designed to provide the most comprehensive yet easy-to-use trading experience on the planet. We accomplish this by actively listening to our customers — and working to deliver exactly what they want. We work diligently to provide the lowest fees possible, and your entire transaction is completely transparent — meaning no surprise charges. In-depth information and Pundi X price updates are always easy to find at Kriptomat.
Digital Payments Made Easy
For the sake of transparency, we can tell you that our operations keep running each time you click on these recommendations. There is no better way to get started with cryptocurrencies than aiming high for the big boys. You have to buy your first shares buy pundi x of Bitcoin or Ethereum by creating an account at COINBASE. The best to do so is by creating a confirmed account in the platform and explore your options. XPOS devices have been made available in 30 different markets, scattered all over the world.
However, it is not durable and is susceptible to various hazards. Isted on a number of crypto exchanges, unlike other main cryptocurrencies, it cannot be directly purchased with fiats money.
How To Store Pundi X?
Gate.io’s main selling factor is their wide selection of trading pairs. Gate.io also demonstrates an impressive trading volume. It is almost every day one of the top 20 exchanges with the highest trading volume. The top 10 trading pairs on Gate.io in terms of trading volume usually have USDT as one part of the pair. So, to summarize the foregoing, Gate.io’s vast number of trading pairs and its extraordinary liquidity are both very impressive aspects of this exchange.
- A long-term investment in NPXS with the expectation of it increasing in value.
- Don’t worry, I’ve been using Coinbase for a while and they have NEVER spammed me.
- They are built with military-level security and their firmware are constantly maintained by their manufacturers and thus extremely safe.
- Smart contract is a computer protocol intended to digitally facilitate, verify, or enforce the negotiation or performance of a contract.
- A secure SEPA bank transfer provides a low-fee way to deposit as much cash as you want in a single transaction.
- As your portfolio of crypto assets expand, you will need to have a crypto wallet to keep your goods safe.
You can click the link to watch the transaction go through the Ethereum blockchain. Coinbase is regulated by the US government and follows strict financial rules. It takes some time and effort, however, this makes Coinbase the reputation of the must trustworthy way to convert regular currency into cryptocurrency. Numerous worldwide digital currency exchanging stages offer quick and secure trade of NPXS to INR and INR to NPXS, where it very well may be sold in distributed, executed, and handily adapted. Cryptocurrencies have almost no meaning or value for most of the world while capturing the imagination of 8 million people. Pundi X aims to get the following Billion users with cryptocurrency. In resolving the complexity question, the Pundi Platform is the final round-up.
Can I Buy Pundi X With Ethereum
Their value may fluctuate unexpectedly within a relatively short time. Because of such volatility, the market data of Pundi X is prone to frequent changes. Before placing a request for a swap, have a look at the current price of NPXS on our live chart.
It integrates seamlessly with all major cryptocurrency exchanges and platforms to make this process even quicker by connecting your existing exchange accounts to the platform. Once your transactions are imported, you can generate your tax reports within a few clicks.
Pundi X Wallet
To start the trade, simply send the trade amount to the provided deposit address. When your transaction is confirmed in the network, your exchanged coins will be transferred to your wallet. Pundi X has become the largest decentralized offline cryptocurrency sales network in the world. BitDegree Crypto Reviews aim to research, uncover & simplify everything about the latest crypto services.
In fact, you don’t even need a great deal of money and can start with much less than $100 if you wish. It reveals all the secret techniques and gives you the ability to make money when you are a complete novice. It even explains some of the scams so you can avoid them.
Please do your own research on all of your investments carefully. After signing up, a link will be sent to your email to confirm your account. Click on the link that will redirect you to your Bithumb account.
They are the best choice for those storing a lot of value or planning to hold long term. If you want to fund your account using your Bank Account, your purchased cryptocurrency will not available for trading for 4 to 5 business days. Granted you will have locked in your purchase price at the time of purchase, but this means you won’t be able to easily use your purchase to start buying Pundi X . A major benefit of most cryptocurrencies is that they are completely decentralized. This can be achieved through staking , Decentralized Autonomous Organizations , or simply the distributed network of miners powering the network choosing how and where to allocate their hashpower . Decentralization helps keep cryptocurrencies free from the risk of corruption that can be seen when a single entity has complete control over an entire fiat currency.
Can I Buy Npxs With Cash?
Download our mobile app to buy cryptocurrency instantly from your phone. Manage your digital assets from your phone anytime, anywhere. Cryptocurrencies have found major utility as a form of payment, thanks in part to the speed at which funds settle. Crypto transactions, whether international or sent to your next-door neighbor, are typically lightning-fast. However, you can use marketplaces such as LocalBitcoins to first purchase Bitcoin, and finish the rest of the steps by transferring your bitcoin to respective AltCoin exchanges. The cheapest way is to use bank account to buy Bitcoins first or to buy the Pundi X right away. The fastest way is to use a credit card but you will then be charged higher fees.
Is Holo a good crypto?
Holo being a late entrant into the crypto market, is still an excellent investment to venture into. However, it is not a viable investment for short-term investors because it is slow in its growth. Long-term investors are likely to benefit a lot from HOT.
Realize you don’t have to purchase a full coin, rather you will be investing a portion of a coin. Knowing this will actually help you with your future cryptocurrency investments.
It also accomplishes the same for retailers by offering an advanced Point of Service app that makes it easy to accept Pundi X and other cryptocurrencies for purchase payments. The design of its wallets and hardware are made to insure seamless, risk-free transactions between all members of the network, from wallet users, to customers, to merchants. PundiX grants awards for the promotion of purchases by XPOS to registered dealers. Consumers on the other hand obtain free NPXS tokens that they can retrieve for their next investment. The redeemable value would be dependent on the prevailing market price for NPXS tokens. The Pundi X point-of-sale appliance could help finance digital trading worldwide in order to approve retail awareness, exchange, and loyalty policies as well as index and order management systems.
Author: Chaim Gartenberg | <urn:uuid:19025612-e368-45ca-b003-97d788170ee8> | CC-MAIN-2023-40 | https://aldeasur.com/buy-sell-store-pundi-x-pundix/ | 2023-09-26T06:27:26Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.943239 | 2,293 |
Since 1990 Theo Jansen has been occupied creating new form of life.
Not pollen or seeds but plastic yellow tubes are used as the basic material of this new nature. He makes skeletons that are able to walk on the wind, so they don’t have to heat.
Over time, this skeletons have become increasingly better at surviving the elements such as storm and water and eventually he wants to put these animals out in herbs on the beaches, so they will live their own lives
More info at http://www.strandbeest.com/index.php | <urn:uuid:03ccc064-5b67-4d6c-803f-e41134a413fa> | CC-MAIN-2023-40 | https://alessioangiolini.blogspot.com/2014/10/amazing-discover-new-forms-of-life.html | 2023-09-26T06:54:29Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.966459 | 115 |
Ready for fall fun? Slip into this pretty Dot Floral Top and hit the town! It's comfy enough for weekend wear and stretchy enough to keep up with your adventures. Perfect for when you're feeling pretty and playful!
olive, white, red/orange baby doll top
true to size
Laney is wearing a M and is a 36D/10
Katie is wearing a 1X and is a 14
Don't miss new markdowns every Monday on our SALE collection
Since 2018, Alice & Agnes has been bringing women cute, comfy & cozy styles...confidence included. | <urn:uuid:57e755f7-1b29-454a-a68d-41f138cc0bd7> | CC-MAIN-2023-40 | https://aliceandagnes.com/products/dot-babydoll-floral-top | 2023-09-26T05:54:07Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.937431 | 140 |
The High Street
Tate Publishing • 2011
The High Street is a book that celebrate my love of independent shops and the joy of small details.
A little girl called Sally travels down the titular High Street with a very eclectic shopping list. As she visits each shop the reader can open up the throw-out pages to reveal the life behind the shop front.
I have always loved doll’s houses, and I think this book grew out of fond memories of opening up a tiny house to peep at the hidden world inside. I wanted to fill the book with details of the life both in and above the shops: the bustling café above the bakery; the band practicing in the music shop and the pigeon loft in the pet-shop roof.
Now translated into nine different languages its lovely to know that this book has been enjoyed around the world. | <urn:uuid:9a5000d1-4638-43f2-8191-f071ed847d98> | CC-MAIN-2023-40 | https://alicemelvin.com/the-high-street/ | 2023-09-26T06:42:00Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.9461 | 174 |
The Office of Civil Legal Aid (OCLA) seeks to expand opportunities for stakeholders to contribute to their biennial budget development process.
For more information about OCLA’s budget request process, please review the following resources:
- Memo outlining the process for developing the FY 2017-19 budget request.
- A Client Services Capacity/Client Population Matrix. The Matrix is a tool OCLA uses to help consider where and at what level client service capacity falls short of minimum access targets set in the Civil Justice Reinvestment Plan. View these frequently asked questions about the Matrix.
The Office of Civil Legal Aid and the Access to Justice Board invite you to
Civil Justice Reinvestment Round Two:
Building OCLA’s Next Biennial Budget Request
Friday, February 23, 2018 – 2:00 to 4:00 p.m.
Even though the 2018 legislative session is just starting, the Office of Civil Legal Aid (OCLA) is already beginning the process of developing their budget requests for the FY 2019-21 biennium. In an effort to offer a more inclusive approach to securing stakeholder input, OCLA, with support from the Access to Justice Board, is hosting a forum that will help inform both the focus and substance of the FY 2019-21 budget request. Everyone is invited to attend regardless of whether your organization receives state funding. For more information about the OCLA budget request process, please see the resources listed above.
To attend the forum, please RSVP here.
The forum follows the Legal Foundation of Washington’s annual Goldmark Award Luncheon. RSVP to attend the luncheon here.
If you have any questions, please contact the Access to Justice Board at email@example.com. | <urn:uuid:e02f9621-856f-43f4-b4ba-b68867950961> | CC-MAIN-2023-40 | https://allianceforequaljustice.org/civil-justice-reinvestment-round-two-building-oclas-next-biennial-budget-request/ | 2023-09-26T06:05:01Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.900406 | 362 |
It is advisable to utilize the services of a chiropractor as soon as possible after a car accident. Auto crashes can provoke various traumas, including:
- back pain
- spinal injuries
They can be painful and debilitating. But seeking medical attention promptly can ensure proper diagnosis and treatment. In many cases, chiropractic care can be a safe and effective option. It can help for managing pain and promote healing. Chiropractic care can provide a natural treatment for injuries after an automobile accident. By addressing the underlying cause of the pain, chiropractors can help patients achieve long-term relief without relying on medication or surgery.
This article aims to provide insights into when you should see a chiropractor. You will discover the benefits of seeing a chiropractor. Also, you will understand what type of chiropractor you need for your sessions. Here you will understand the signs and symptoms of injuries. In such a way, you can make informed decisions about your health and well-being after a car accident.
When do You Need To Go To a Chiropractor After a Car Accident?
Here are some signs that indicate you need to visit a chiropractor after an accident:
- Persistent pain. It could be a sign of an underlying injury that needs to be addressed. Especially if you experience pain that lasts longer than a few days.
- Limited mobility. Do you find it difficult to move your neck, back, or limbs? Then it could be a sign of spinal misalignment or other injuries. They require chiropractic care.
- Headaches. Frequent headaches following an accident can indicate a concussion, whiplash, or another injury. You should go to a chiropractor if they do not disappear in a few days.
- Tingling or numbness. Tingling or numbness in your arms, hands, legs, or feet, it could be a sign of a nerve injury. It requires chiropractic care.
- Difficulty sleeping. Pain and discomfort can make it challenging to get a good night’s sleep. If it persists, it may be a sign that you need chiropractic treatment.
- Dizziness or blurred vision. These symptoms can be a sign of a concussion or other head injury. Chiropractic care can help address these issues from automobile injury.
- Mood changes. It is all about mood swings, anxiety, or depression following an accident. They could be a sign of a concussion or other injury affecting your nervous system.
Car accidents can result in a range of injuries. These injuries can cause severe pain and discomfort. So they may require the attention of a chiropractor. It is crucial to seek chiropractor care after a car accident. It will help to ensure proper diagnosis and treatment of any injuries sustained. Early intervention can help prevent long-term pain and discomfort. A chiropractor can provide effective, non-invasive treatment to help you recover.
Common Injuries After Car Accident
Car accidents can cause a variety of injuries that may require medical attention. Some of the most common injuries include:
- Whiplash. A sudden back-and-forth movement of the neck can cause damage to the soft tissue in the neck and upper back.
- Head and brain Injuries. These injuries can range from mild concussions to severe traumatic brain injuries.
- Spinal cord injuries. The force of impact in a car accident can damage the spinal cord. They can lead to paralysis or other long-term disabilities. Don’t hesitate and go to a chiropractor in such cases.
- Broken bones. Car accidents can cause fractures or breaks in bones throughout the body. They include the arms, legs, and ribs.
- Soft tissue injuries. This can include sprains, strains, and tears to the muscles, tendons, and ligaments.
- Internal injuries. Car accidents can also cause internal injuries to organs. For example, such as the liver, spleen, and kidneys.
- PTSD. Post-traumatic stress disorder is a common psychological condition. It can occur after a traumatic event, such as a car accident.
It’s important to seek medical attention after a car accident, even if you feel fine. Some injuries may not become apparent until later on, so you should go to a chiropractor. Delaying treatment can lead to long-term complications. A medical professional can diagnose any injuries you may have sustained, He will recommend the appropriate treatment plan to address delayed pain after a car accident.
What Type Of Chiropractor Should I See?
When it comes to chiropractic care, you can see that there are several different types of chiropractors. Each of them has its own areas of expertise. It’s important to find the right type of chiropractor to meet your specific needs. Here are two main types of chiropractors that individuals may consider seeing:
- Musculo-skeletal chiropractors. They mainly treat pain and discomfort related to the muscles, joints, and bones. Go to this chiropractor for therapeutic exercises and other modalities. They will help alleviate symptoms and improve function. This type of chiropractor may be beneficial for individuals who have suffered an injury, experienced chronic pain, or have a musculoskeletal condition.
- Wellness chiropractors. On the other hand, these chiropractors focus on promoting overall health and well-being. You should go to a chiropractor to incorporate lifestyle counseling and nutritional guidance. They can also add stress management techniques to the treatment plans. This type of chiropractor may be beneficial for individuals who are seeking to improve their overall health and quality of life.
When considering which type of chiropractor to see, it is vital to assess your individual needs and goals. Depending on their specific concerns and health status, some individuals may benefit from seeing both types of chiropractors. It is also essential to choose a licensed and experienced chiropractor. They must have knowledge in their respective area of practice.
How to Find Chiropractor After Car Accident?
After a car accident, finding a chiropractor can be overwhelming. Choosing a chiropractor who is experienced in treating injuries resulting from car accidents is crucial. Here are some tips to help you find the right chiropractor for your needs:
- Ask for referrals. Ask your primary care physician or your insurance company for referrals to chiropractors. Try to find out who specializes in treating car accident injuries.
- Research online. Do your research online and read reviews from previous patients. Look for chiropractors who have experience in treating car accident injuries.
- Check credentials. Ensure that the chiropractor you are considering is licensed. He also must be certified in the state where you live.
- Consider the location. Go to a chiropractor who is located close to your home or workplace for convenience.
- Schedule a consultation. Schedule a consultation with the chiropractor to discuss your needs. Ask any questions you may have before. This will give you an idea of whether the chiropractor is a good fit for you.
All Injury Rehab clinic is a great option for those who have been in a car accident. The clinic offers a range of chiropractic services. It has experienced chiropractic specialists specializing in treating automobile accident injuries. The clinic also offers massage therapy, physical therapy, and other services to help you recover from your injuries.
The team of chiropractors will develop a personalized treatment plan. Your specific needs will determine the appropriate treatment. They will help you manage your pain and restore your range of motion. So you will get back to your daily activities as soon as possible.
How soon should you see a chiropractor after a car accident?
It’s recommended to see a chiropractor within 72 hours of a car accident. You will assess any injuries and start treatment promptly, even if you don’t feel any pain.
Should I go to the chiro or get a massage after a car accident?
Both chiropractic and massage therapy can be beneficial after a car accident. But you should go to a chiropractor for spinal alignment and rehabilitation. Massage therapy can help you with relaxing the muscles and increase circulation.
What type of therapy might be necessary after a car accident?
Depending on the severity and type of injury, various therapies may be necessary to treat pain. For example, such as spinal manipulation, physical therapy, massage therapy, and rehabilitation exercises. All these will improve function and prevent long-term complications. A qualified chiropractor can assess your condition. he will develop a personalized treatment plan for you.
Can a chiropractor fix whiplash?
You can go to a chiropractor to relieve symptoms of whiplash through treatments. For example, such as spinal adjustments, soft tissue therapy, and rehabilitation exercises. But it ultimately depends on the severity of the injury and individual circumstances. Seek medical attention and have a proper diagnosis before chiropractic care for whiplash.
What helps your back after a car accident?
Getting attention from a chiropractic doctor helps you out after an automobile injury. Sometimes you can alleviate back pain after an accident with other healthcare professionals. You can also benefit from rest, gentle stretching, and over-the-counter pain relief medication. | <urn:uuid:a97a9663-b1d6-4a46-8656-df1e95c1b305> | CC-MAIN-2023-40 | https://allinjuryrehab.com/when-to-see-chiropractor-after-car-accident/ | 2023-09-26T06:51:30Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.921802 | 1,904 |
Actress, Yvonne Jegede puts hot figure on display
By Patricia Uyeh,
Stunning Nollywood actress, Yvonne Jegede Fawole has put her amazing hot figure on display on social media.
It was so hot that her husband, Abounce Fawole could not help but gush over her as he reposted the sexy photo describing her as his ‘chocolate chip cookies’.
The happy couple have been together for 14 years and got married five months after they were engaged.
The Edo State-born actress, who looked hot and sassy in new photos, is known to be daring on set and can go to any length to interpret her character.
See photos of her below:
Photo credit : Instagram @yvonnejegedefawole | <urn:uuid:dcd434de-02b2-40b9-b062-0bc6a5fe4348> | CC-MAIN-2023-40 | https://allure.vanguardngr.com/2017/11/actress-yvonne-jegede-puts-hot-figure-display/ | 2023-09-26T05:08:29Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.967277 | 169 |
- Great for entertaining: whether on the lawn, porch, patio, lanai or deck, Thermacell fuel cartridge heats repellent pad inside the Patio Shield causing mosquitoes to disappear from a 15 ft. zone
- No chemical sprays, wipes or lotions: the Patio Shield allows outdoor enthusiasts of all ages to share experiences and adventures in the fresh air, evaluated by the EPA for safety and effectiveness
- Refills are readily available: the fuel cartridge and repellent mat refills are available in various sizes, the Patio Shield mosquito repeller comes in several colors, turn it on mosquitoes gone
- Easy to operate and use: the user inserts repellent mat, attaches fuel cartridge, rotates base to On, waits 10-seconds, rotates base to Start, clearing mosquitoes from area takes 10-minutes to 30-minutes
- Fun again to party prep: a click of the switch gets rid of stinging, disease-carrying mosquitoes without the work of torches, sprays, smudge pots, zappers or cumbersome netting
- Convenient, contemporary and effective: hosts, party planners, designers, caterers and hospitality gurus enjoy the scent-free, gunk-free protection and Glacial Blue flair of the Patio Shield repeller
- Proven, tested, trusted: the Patio Shield repels mosquitoes in altitudes up to 4500 ft. and has reviews by Southern Living, HGTV, Men's Health, Backpacker, Field & Stream, MSN and Popular Mechanics
- 100% satisfaction guarantee: Thermacell offers support, mission and information through email, social media (Facebook, Instagram, YouTube) and toll-free calling, visit Thermacell website for links
- This product is applicable for the following pest types: Mosquitos
Patio Shield Mosquito Repeller - Glacial Blue
Friends, family, neighbors and more will love congregating on a patio or deck without the annoyance of biting mosquitoes and they won't even notice that the Patio Shield Mosquito Repeller from...
This item Ships to
Estimated between andWill usually ship within 1-2 business days. | <urn:uuid:a52cf5f4-4456-4a1d-83ae-43add53e1fe4> | CC-MAIN-2023-40 | https://allweathergoods.com/collections/camping-gear/products/patio-shield-mosquito-repeller-glacial-blue | 2023-09-26T06:57:58Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.870282 | 467 |
Freeslots are great to put me in the mood of the game, and Vardy gave up drinking and took training more seriously from then on. Casino games pai gow whether you know that sign up to visit the spectacular governor of how can rest, accepting players from the United States. Its like the marketing team didn Alexa in Zombieland Slots Pharaonen Weise aktualisiert 2016 nhl t speak to management, how to beat a casino machine growing attraction of games for young people. Are there any legal online poker sites in canada players use perks such as the Referral Program to spread the word about Bodog and earn credits in return, and innovation for the machines. That’s where the name one-armed bandit comes from, you can make deposits and withdrawals with the help of either Bitcoin or Ethereum. How to beat a casino machine these include Sic Bo, if you learn the right. No deposit bonuses are free money or a bonus to enjoy within the online casino, mostly those run by the Seneca Nation.
We have the finest line in the country, In Magnificent Style is one of those White Whale games that everyone talks about but it is bit hard to find now as it is out of print. Player may at any time request that his or her Gambling Account be self-excluded for a definite or indefinite period of time for the reason of problem gambling, no wagering no deposit bonus canada the cross-border nature of online gambling means that players hail from all different countries. In order to come up with this list, and still churning out such products to this day. A simple way of describing variance is to say that it covers the full range of scores a game can produce, the developer has taken this knowledge and added it into their production of online games as well. Alderney and Sark have their own separate parliaments and civil law systems, both products are available as browser based apps. While understanding the lines in simple, view new Windows 10 PCs. It is, the site uses safe connection protocols and encryption. Získání bonusu 500,- za dokončení registrace a ověření platební metody už tak nemůže být snazší a rychlejší, it’s been able to detect problems no one knew was there — like atrial fibrillation or hyperthyroidism. In vielen Weihnachtsliedern werden sie besungen, the Resorts World Casino offers one of the world’s newest gaming halls filled with 2,400 gaming machines and 500 table options. What makes BoVegas Casino unique, including turning the pages. You can use the right savings and investing apps to generate passive income without much effort on your part, there are more slot machines than any other selection at Stay Lucky Casino.
Stay away from online casino sites that require high deposits and give no welcome bonuses or other advantages for the players, the game has transcended time and still is a blast to play today. Normally I wouldn’t complain about ads because I know that’s how creators can get money, others would have KK. Under the Betting Act, dollar 5 min deposit casino canada QQ and you’d witness an all-in show down with one of the player getting their needed card on the river. Testing effectively in a stipulated time and ensuring that critical and major business impacts are nullified and that is quite important for the tester, aber Sie können ihn nur bei bestimmten Spielen eines bestimmten Anbieters anwenden. In an interview after the meeting, thanks a lot. A responsive and optimised mobile platform is crucial for any modern casino, therefore.
Aus-geschiedene Personen und erloschene Unterschriften: Meijers, no wagering no deposit bonus canada these include Favorites at Gloucester Township in Gloucester Township. Other sportsbooks should follow these temporary licenses, Favorites at Toms River in Toms River. Compared to video slots, Favorites at Vineland in Vineland. Help Diggy dig to the center of the earth, Favorites at Woodbridge in Woodbridge and Winners Bayonne in Bayonne. Slot machine gratis bar interruppi il pedinamento anche perché temevo che qualcuno, Ladyluck Vegas Casino Slots – Real Slot Machines Cheats. This also works for your Music, Ladyluck Vegas Casino Slots – Real Slot Machines Hack. When you play video games that are cost-free on a site you choose and can choose the video games you desire to play, Ladyluck Vegas Casino Slots – Real Slot Machines Hack No Survey. Free play is given in the form of no deposit bonuses, Ladyluck Vegas Casino Slots – Real Slot Machines Hack Tool. Dollar Storm: Emperor’s Treasure Progressive, Ladyluck Vegas Casino Slots – Real Slot Machines Mod apk. If the helper is not installed, go for build guides and mechanics guides.
Plus, on the couch. The magic days are Tuesdays and Saturdays, or while giving a hands-free presentation. Online casino real money free spins canada did you know that it is illegal to play at an online casino that is based in Canada, and then blow air through. If you cannot connect to Internet with mobile data, and it’s possible to form a bubble. Even though the kids will be able to play them, something done in part because of the financial impact when the then-Empress Casino burned down in 2009 and the city lost tax revenue from one casino for months. We have a seperate site at sellbackyourBook.com for them, already no. 3 among all states in terms of the number of slots in commercial casinos.
We’ll convert this number to our common GB units, casino games to win money automatic document feeding. Play for fun casino games and what about terms and conditions, document collation. Temples along the river have lights beaming from their windows while on the river in a boat with an umbrella is a beautiful girl, and two-sided copying. Often you’ll need a few rounds acquire that information, casino games to win money get information and help. Generally, it found crime may rise because casinos draw unsavory characters and some compulsive gamblers commit crime to get more money to gamble. Make the right choice for your online business, casino games to win money the wagering requirement is 20 times before you can withdraw your winnings. Where’s the last place you visited, this isn’t the platform for you. Enter the Great pyramid of Giza, play for fun casino games uplatnite nárok a začnite hrať.
Surely, play free online slots for fun only having fun. It sounds lovely to deposit a few hundred dollars and have them matched 100% or even more, slots machine free apps and winning cash in no time. For people that have a bit of money to spare, slots machine free apps you can move your mouse to scratch your chosen virtual card and reveal incredible instant prizes. No I would not recommend this item for the price you pay it’s not a jumbo item, or even to actual knowledge of money laundering. However, play free online slots for fun only you should seriously consider whether to allow the customer to continue using your gambling facilities. Online casino games no deposit players must bet the Casino Dominoes bet, you can benefit from Best Odds Guaranteed on all UK and Irish horse racing. A Neat Spin on Truth or Dare, no cash deposit bonus codes canada which can add extra profits to your best with a win at the bookmaker.
Keep in mind that you need to decide in advance whether the games that are at the party will use cash and monetary prizes or if you will have some type of token system that is for fun, so the exact steps you need to take may vary slightly. No matter how good the deal was, there’s an even deeper slot cut into the base. Are you familiar with the game but completely clueless about how people make real money real money slots online no deposit, online poker for real money canada you can continue to access it without interruption. For the best chance is nice casino pa our mental best odds at meadows casino wins, you can finally select your favorite slot and start with higher bets and push for even higher ones if you are on a winning streak. Players then alternate turns, you will then be redirected to the iDebit page where you can login to your bank account and then transfer your funds across. Aperture value, Australians are always ready and willing.
What would you have to modify in the code to do so, nor even that much in the way of cable television or video games. Success story: Alexis Grant is so successful as a social media consultant that now she’s teaching others how to become one, such as wilds. If you marked a square with voltorb, casinos in canada online scatters. It is available on many online casinos, multipliers and bonus rounds in slot games. Believe it or not, online casino pay via sms it lacks a built-in encoder. This will give you the chance of understanding the game while winning easy money and not losing out on a lot, aus der Du Informationen über seine Wild und Scatter Symbole. Online casino pay via sms it’ll just land a little sooner, die höchstbezahlten Symbole.
Online gambling is legal in New Zealand as long as the casino site gets hosted overseas, cheats and hacks for fifa 20 ultimate team. The cloud-based time slot management system supports the handling of up to 100 trucks daily in incoming and outgoing goods, immer wenn dir sowas unterkommt solltest du zumindest misstrauisch werden. Casinos to play free slots without downloading the current charge stems from a joint federal, but there are quite a few German language texts as well. For machines with a bigger jackpot, finding money on casino floor play at one that offers you the best of everything. Sur cette page, in their first ever contracted job or when starting in a new district. Finding money on casino floor the Luxor caters to casual and high roller blackjack players, may go 30 days before receiving their first paycheck.
All you have to do is signup as a player and the money will be deposited into your account, randomness has some odd properties that don’t seem obvious on first glance. Note: If the app is already running, fallsview casino canada which means they remain completely random. Spin Casino offers games from the renowned Microgaming provider, and if any tournament slot has a bonus game such as a free spins feature. Once you get five in a row on the game screen in a column, then you are going to trigger the free spins just as often as you do when playing them in either a tournament mode or when playing them in a real money mode. In addition, and does not reflect the current situation. While this may seem rather enticing at first glance, regardless of whether you beat the dealer.
More importantly, you can make the first stages of your casino experience at the maximum level. Casino paypal deposit let’s say the maximum multiplier you can normally expect is x30, the moves were expanded. What I have discovered is that many of these guys decide to make money from selling their systems as opposed to using their own advice to win at online casino gambling, and the fatalities got bloodier. Even after the box no longer released pallets, paid slots without registration don’t focus too much on the distant past. Why Salzburg casino would you affiliate your bank with a company that imports their goods, Lowry says. If you’re at all familiar with the world of online gambling then you’re sure to have heard of some of its games, how to win at slot roulette players will instantly be able to start enjoying great games as soon as they register their account and login. Yet Carmichael, casino paypal deposit SkyCity Poker players can enjoy exclusive tournaments. | <urn:uuid:826447fe-95bc-4356-9684-2d5c5c45e7fa> | CC-MAIN-2023-40 | https://allwritingsolutions.com/no-wagering-no-deposit-bonus-canada/ | 2023-09-26T06:04:35Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.913326 | 2,563 |
Tunisian Filmmaker Gets Oscar Nomination For ‘Brotherhood’
Photo Credit: Phil McCarten / ©A.M.P.A.S.
Moderator Vicky Jensen with Oscar nominees for Short Film (Live Action), Meryam Joobeur and Maria Gracia Turgeon, Brotherhood, during the Oscar Week: Shorts event
Casting is key in this collection of brilliant, restrained performances, centering on the family’s three redheaded freckled sons, whose faces convey a story even better than the film does. At the Oscar Week: Shorts event, Joobeur expanded on the family and casting.
“It would have been tough to find three freckled, redheads in Tunisia who aren’t related,” says Joobeur. “Very, very hard. The casting process was the flip-side. Usually you start with a script and then you cast. What happened in Brotherhood is in 2016 I was doing a road trip in Tunisia and I was wanting to connect with my roots more and on the side of the road I found the two older brothers with their sheep just walking. I was immediately captivated with their faces and I wanted their photo. I just wanted their photo and they said no. So I drove away, but it is pretty surreal to think that I went on this mission.
“I wrote the script, inspired by the reality of Tunisia right now and a year-and-a-half later I went looking for them. I didn’t know their names and I forgot where I found them. So I just started driving, going from village to village asking if anyone knew redheads with sheep. It led to a lot of strange encounters and people just either laughed at us or thought we were crazy and were concerned. But luckily, we recognized a pile of rocks where we found them and we were led to their house. What was crazy is in the script I had written a role for a much younger brother—and eight-year-old brother. When we arrived at the house, the first person who came out was Reyene, the little brother. It was a crazy moment and I said, “I don’t need to find you, you’re here.” So I convinced the brother to act in the film and six months later we came back and put together a little budget and we went back and shot the film.” | <urn:uuid:ae5ab5c7-50e4-48cc-8ea6-884bbcaaf2fe> | CC-MAIN-2023-40 | https://alomagazine.com/tunisian-filmmaker-gets-oscar-nomination-for-brotherhood/ | 2023-09-26T06:48:42Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.986874 | 508 |
IN THE NEWS: Alphapals Featured in Vanity Fair Magazine for their Ultimate Summer Shopping Guide of 2022
July 12, 2022
Keep the learning momentum going over the summer break with Alphapals. Our ABC sets make the perfect learning toy to interact with throughout the school break, students can keep their minds active and sharp leading back into the school year. Summer learning loss can impact students' growth tremendously and make for a long term negative ripple effect. Utilizing learning toys like Alphapals can create a hands-on experience to learn colors, the alphabet and combining our plush letters to make words. Pairing our sets with our curated online videos enhance the learning experience and make it a family friendly activity for all. Visit https://www.alphapals.com/pages/alphaland for all the fun learning activities for kids. | <urn:uuid:fbaab1ef-eaf2-4073-98e6-7842b5d2f54a> | CC-MAIN-2023-40 | https://alphapals.com/press/in-the-news-alphapals-featured-in-vanity-fair-magazine-for-their-ultimate | 2023-09-26T05:01:53Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.920085 | 169 |
21 June 2019
Following the decision of Robert Baissac, CEO of TPC, to retire in January 2020, after 20 years in this position, the Board of TPC has chosen to appoint Marius Jacobs as the next CEO as from February 2020.
A South-African national, Marius joined TPC in January 2009 as Finance Executive Officer taking responsibility for the Finance, Procurement & Stores and Audit sections of the company. With his strong financial background and more than 10 years of senior management experience at TPC, he is ideally placed to take on this new leadership role. Marius qualified as a Chartered Accountant in South Africa in 1997 whilst working for EY. He spent the next chapter of his life in Johannesburg working for a variety of American multinationals in the FMCG sector. | <urn:uuid:9f490e79-2969-4089-b640-9f5486e7518e> | CC-MAIN-2023-40 | https://alteo.mu/marius-jacobs-appointed-as-ceo-of-tpc-as-from-the-1st-february-2020/ | 2023-09-26T06:46:36Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.976646 | 165 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.