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MIRI accepts donations from donor advised funds (DAFs). Typically, such donations are sent from funds hosted by 3rd party institutions such as Fidelity Charitable, Vanguard Charitable and Schwab Charitable.
If you have any questions, please email Colm(@intelligence.org). | <urn:uuid:547b61c9-7bbc-4645-b913-da18feb0784f> | CC-MAIN-2023-40 | https://intelligence.org/donate/ | 2023-09-26T06:30:06Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.881659 | 237 |
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We already know that the facility of a good fragrance is potent. It could trigger memories, invoke deep feelings, or remind you of a single individual. So if you happen to’re gifting a scent this vacation season, it is essential to make it a superb one. And you have choices: There are particular person scents, perfume reward units, candles, and different fragrance presents to contemplate.
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https://www.attract.com/gallery/fragrance-gift-sets-and-perfume | 27 Perfume Reward Units, Perfumes, and Candles for the 2021 Vacation Season | <urn:uuid:31f85aa5-f9e2-4ba8-b7dd-3f75c5559e5a> | CC-MAIN-2023-40 | https://interreviewed.com/27-fragrance-gift-sets-perfumes-and-candles-for-the-2021-holiday-season/ | 2023-09-26T06:18:57Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.948608 | 378 |
Image via Bravo
Vanderpump’s Rule Stars James Kennedy and Raquel Leviss have officially broken up.
The couple, who have been together for five years and got engaged in May, announced their separation on December 5 in a Joint statement shared on their respective Instagram accounts. The announcement comes shortly after rumors started circulating that the ex-couple may have broken up, based on a season nine reunion special filmed last week.
Kennedy and Leviss said in the statement shared alongside a photo of the duo in what appeared to be a Bravo studio, “After the amazing 5 years we’ve had together, we’ve decided we have two different goals and decided to stop getting engaged.. We love each other a lot, but we are no longer in love. We want nothing but the best for each other so keep all thoughts positive. Send love.”
Based on Everyone magazine, shortly after the breakup allegations, an unknown source claimed that the two ended their engagement in Vanderpump’s Rule band reunion. According to the source, Leviss returned the ring on air.
Kennedy and Leviss first met in December 2015 while DJing a New Year’s Eve performance. This year, the couple got engaged when Kennedy proposed to Leviss during a Coachella festival-themed event, which was later shown on the reality series.
At the time, Kennedy and Leviss shared the news of their engagement on their separate social media accounts. Leviss stated, “James proposed at ‘RACHELLA’ iconic Empire Polo Fields on Friday night… And I said YES! I’m on Coachella moon. “While Kennedy shared, “LOVE OF MY LIFE, said yes.”
Details surrounding the couple’s split are yet to be revealed, but Andy Cohen will give an answer when Vanderpump’s Rule broadcast reunion. It is currently unknown whether the couple will share custody of their Goldendoodle, Graham.
https://wegotthiscovered.com/tv/james-kennedy-and-raquel-leviss-from-vanderpump-rules-call-it-quits/ James Kennedy and Raquel Leviss from The Vanderpump Rule call it giving up | <urn:uuid:1da0b12c-7e08-42f6-b8fd-5aecb31d405e> | CC-MAIN-2023-40 | https://interreviewed.com/james-kennedy-and-raquel-leviss-from-the-vanderpump-rule-call-it-giving-up/ | 2023-09-26T04:48:51Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.934842 | 475 |
As an AI language model, I am unable to provide you with a specific article_title as I don’t have any preference. However, I can provide you with some tips on writing an engaging and informative article.
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In conclusion, writing an informative and engaging article requires careful planning, research, and attention to detail. By following these tips, you can create content that resonates with your readers and helps to establish you as an authority in your field. | <urn:uuid:b3d27271-5309-4d78-96e5-5448eb0d893d> | CC-MAIN-2023-40 | https://intoourworld.com/2023/03/21/why-vaccines-are-essential-for-a-healthy-community/ | 2023-09-26T05:21:37Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.928908 | 295 |
3 Indicators That Can Tell You the Market’s Next Move
On Monday, I was in the city spending some time with my friends at Yahoo Finance. As always, I thank them for their hospitality and Jeff Macke for the engaging conversation.
With the volume and velocity of information out there, trying to get a read on the stock market is like attempting to get a sip of water from a firehose. Thankfully Paul Schatz of Heritage Capital has three ways to check the health of the market and durability of its trends. They don’t work every single time but Schatz says these are great “tells” as to whether or not what’s happening from day to day is reality or a mirage.
1. High Yield Bonds (HYG)
More commonly known as “junk bonds,” high yield corporate debt has been one of the favorite plays for investors who want decent cash flow with slightly more safety than stocks. Historically low rates on U.S. Government debt have made junk bonds an attractive way to play in between bonds and equity.
That’s why junk is the canary in the coal mine according to Schatz. Risk appetites should be relatively consistent across the board. In other words, if stocks are rising, corporate debt should be moving higher as well.
“If the market rallies and high yield does not participate that’s worry sign number one,” says Schatz.
2. S&P 400 Mid-Caps (^MID)
The S&P400 is a measure of stocks not quite big enough to make the cut for the S&P 500 (^GSPC). Companies this size tend to be hit harder by economic fluctuations than those with larger balance sheets or more lines of business. This makes the mid-caps a way to gauge the real health of the earnings environment for corporate America.
“Traditionally in bull markets mid-caps lead,” Schatz says. When the S&P 400 isn’t leading, or at least playing along with a market rally, it’s time to take profits.
3. Dow Jones Transportation Index (^DJT)
As would be expected, the Transports are a collection of 20 American companies in the business of moving things from point A to point B. Railroads, airlines, and trucking basically. Even in a virtual age most traders regard the Transports, or “Trannies” as a good gauge of underlying economic activity.
By market tradition, real bull markets only come when both the Dow Jones Industrial Average (^DJI) and the Transports are breaking out together. At the moment there’s little risk of either happening, but Schatz suggests traders stay on the lookout.
“If the Dow Jones Transports can take out the April highs I think it’s a straight 5 – 10% shot higher,” he says. Though he concedes it’s a “long way to Tipperary” before they do. | <urn:uuid:f84aaa39-aa7b-4f04-b9a5-bbfcfa685c57> | CC-MAIN-2023-40 | https://investfortomorrow.com/blog/3-indicators-that-can-tell-you-the-markets-next-move/ | 2023-09-26T05:01:26Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.944693 | 636 |
Have you known about a land course previously? Regardless of whether you are new to the land business, there is a decent opportunity that you have. Despite the fact that you might have known about a land course previously, do you know precisely exact thing one is?
With regards to land courses, you will find that they arrive in various configurations. For example, there are land courses that are intended to help individuals, very much like you, earn enough to pay the rent as a realtor, courses that assist property holders with selling their homes, courses that furnish imminent home purchasers with significant data, as well as courses that are intended to present land effective financial planning. In the event that you are hoping to bring in cash with the purchasing, selling, or leasing of land speculation properties, you will need to zero in on courses that give home purchasers significant data, as well as those that cover the intricate details of land effective money management.
One of the many justifications for why you are encouraged to take a land course that is intended to help planned home purchasers is so you will know precisely exact thing to search for in a property. Assuming this is your most memorable time purchasing land properties or even your subsequent time, you may not precisely know the intricate details of purchasing land the avenir. There are a few supportive tips, such as utilizing the administrations of a realtor or having each imminent home go through a primary investigation prior to purchasing, that you may not know about. Taking a land course that spotlights on these significant hints will make it simpler for you to purchase land properties later on, whether you are getting them for your very own utilization or to create a gain from leasing or exchanging.
Notwithstanding a land course that gives forthcoming home purchasers tips, you are likewise encouraged to inspect land courses that cover land ventures. In the event that you might want to bring in cash as a land financial backer, you can do as such, yet you should initially understand what you are doing. Assuming this is your most memorable time trying land ventures out, you will need to ensure that you know precisely exact thing you are doing, as it will allow you a superior opportunity for progress. To that end it is prompted that all planned land financial backers first take a land course, especially one that teaches members on land speculations, as well as offers tips.
On the off chance that you might want to get familiar with land putting or simply purchasing a home as a general rule, you are encouraged to take a land course prior to continuing any further. To find success in the land venture industry, you should be taught on precisely how land speculations work. For an enormous determination of online land courses, you are encouraged to play out a standard web search, ideally with the expression “land courses.” On the off chance that you would like to take a nearby land course, you are instructed to reach one concerning your neighborhood realtors for extra data, as well as watch out for all neighborhood grouped promotions. | <urn:uuid:1131dcb0-e902-4eb5-8dd7-707846ea72ed> | CC-MAIN-2023-40 | https://ipadstores.com/how-a-land-course-can-help-you/ | 2023-09-26T06:22:43Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.964935 | 607 |
The polygamy investigations in Texas has brought to light a scam that instigates and perpetuates the motivations of people who grasp at the promise of a heaven. The requirements of life are depicted to include various acts which will translate into approval by a deity for admission to a palace that lasts forever and has attributes that are superior in some respect to actual living on earth. This can also be observed by the Muslims willing to crash into buildings in the name of obtaining an eternal life in a place where virgins abound and an allotment of 72 is promised. Promised by whom? By those who are willing to take ancient scribbling and be the anointed translator and/or spokesperson telling the followers what is the true interpretation of the ancient scribbling.
Promising and projecting is always the method of those who understand how to prey on the fears of the human psych. There was a “prophet” in the House of David located in Benton Harbor Michigan who promised his followers that by following his teachings they would never die. When he died the followers finally figured out they had been hoodwinked. Since there is no way to disprove the promises of what happens beyond the grave this is the prefect venue for the charlatans that capitalize on this approach to instill fear and therefore motivate followers to act in accordance with the wishes of the hoodwinker. The reason there is no way to prove what happens beyond the grave is because living evidence of the dead is an impossibility. Addressing this issue the Christians posited that the dead could be brought back to life if they had sufficient standing with the supreme deity. Since they couldn’t duplicate or even point to the person resurrected as living on earth they needed to posit another place to live and this led to the invention of heaven.
The standard argument to substantiate this special place is the reference to the “inspired” word. Inspired word requires the utilization of the method of faith. For when asked how we know the word is inspired we get the circular argument that the written word says so. Such a logical fallacy requires we believe in spite of the contractions, in spite of the lack of evidence and succumb to the fear that if we don’t believe we will not see this special place that has no known location, has various contradictory attributes and allows only certain dead people to enter ( those who live by the prescribed dictates of the earthly hoodwinkers).
If you look at the descriptions of the place called heaven you find the description contains earthly attributes like golden streets even though what a street is needed for is never questioned. The notion of virgins that eventually lose their virginity and become “used” certainly makes one wonder what the long term prospect consists of. Appealing to naive young males thinking only of a prolonged orgy without question and the prospect of a sustained hormonal gratification motivates these vulnerable scamps to promise to do whatever is necessary to get to this place that certainly has no counter part on earth. All that is required is to get the victim to believe and this is what the religious leaders know and promote. It is easy for these leaders to promise and profess they believe what they are promoting but how many of these leaders present an example of their “faith’. How many leaders like Osama Bin Laden show by the example of suicide bombing of their own body the desire to achieve what the young naive followers are promised? Or consider the opulence of the Pope and his cry for charity and denial of material pleasures. The obvious ploy of the televangelists with their wealth obtained from guaranteeing eternal life to those who think what they are contributing to is a better world that a deity of all powerful ability cannot see without their paltry contributions placed in the hands of these charlatans living in opulence. P.T. Barnum at least offered entertainment. The promise to alleviate fear of death offers nothing but a play on the emotions of the person who is willing to believe anything to not have to face eternity in an adverse environment. This of course brings up the concept of Hell. This idea was necessary, for those who in true religious altruistic fashion, were not concerned with seeing what they were required to despise in life ( such as gold ) yet would respond to fear if enough punishment could be attached to the experience. Thus came the gnashing of teeth , the burning of flesh, the eternal anguish and pain with no hope of ever being alleviated. This attached to a dead body that somehow wasn’t dead registered in the minds of those willing to believe at any cost just to avoid what could only be projected. Since this approach could terrify the believer who really didn’t care about eternal reward but didn’t want eternal adverse consequences, it was included in the message to cover as many followers as possible. Of course the greatest condemnation was reserved for those who denied the message and the premises of the hoodwinkers. Eternal damnation was not good enough for these nonbelievers for they threatened the very essence of the scam and were hastened to their death by laws and religious dictates. Thus the infidel, the non believer, the pagan was expendable as they would never become followers and live in fear so they must be killed and tortured to create an example what consequences were expected by questioning. This is also the code and method of criminal gangs who offer ‘protection”.
The fear of death has been a real boon for charlatans. They have lived in opulence, ruled by decree, and never had to worry that someone would come back from the grave and say, “You were wrong.” Like the Global Warming fanatics the future they talk of is so far removed from their life span that accountability is impossible. Like Congress who believed their promises would not blow up during their tenure, the promises of fantasy continue and the followers nod and acquiesce hoping the impossible will somehow come true.
Simply put, there is no such place as heaven either on earth or anywhere else you can imagine. It is the product of a human mind that tried to posit a reward for belief. You will recognize the requirement of belief is always tied to the “reward” of heaven. Get people to have faith and believe and you can sell them anything, This works for quackery, snake oil, religion, diets, supplements, exercise machinery, sun screen, copper bracelets , swamp land and even columns appearing in the New York Times. Look to the gullibility of man to believe without proof. Ask for belief and keep the mantra going and before you know it there will be a following. Conspiracy theories erupt, religions arise, and all thrive on the number believing instead of the truth of the contentions. Rewards geared to a better life abound in the political arena and rewards geared to an afterlife abound in religions. But both are empty promises of charlatans who cannot deliver. The socialistic heaven of today’s politicians ignores the costs of creating such an environment and fail to account for the law of deficit spending which always leads to bankruptcy via inflation. The religious heavens will always be proposed by the advocates willing to promise and project whatever will motivate believers to follow , contribute and never question. This is the pattern and the consequences of faith, the most destructive mental process that the human mind can cling to. It is far better to question and learn than to believe and hope for what can never be. Determining what is possible comes from questioning and concluding on the basis of evidence. Where no evidence exists, the promises and visions of man cannot be substantiated by blindly believing them. The argument that they may be right is false. There is no possibility that the impossible can be.Tags: religion | <urn:uuid:d6f298fb-6a4b-4165-8a7d-10095ea7b424> | CC-MAIN-2023-40 | https://ipatriot.com/atheist-calls-heaven-scam/ | 2023-09-26T05:59:17Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.967305 | 1,563 |
MassPRIM to vote on RFP for real estate consultant
At a March 19 meeting , the real estate and timberland committee of the Massachusetts Pension Reserves Investment Management Board voted unanimously to recommend that the PRIM Board approve the issuance of an RFP for general and project real estate consulting.
The board will vote on the approval at its next meeting on April 1.
MassPRIM issues an RFP for consulting services every three years and is open to hiring more than one consultant. The incumbent consultant, The Townsend Group, will be eligible to reapply and be rehired for its current role.
The Pension Reserves Investment Trust fund that MassPRIM manages is valued at $58.2 billion as of Feb. 28, 2014. Its real estate portfolio is valued at $5.04 billion, comprising 8.7 percent of the total fund. MassPRIM’s target allocation to real estate is 10 percent, and the board voted to set aside up to $550 million for real estate investment in 2014.
In 2013, the real estate portfolio had returns of 10.8 percent. The board’s five- to seven-year return assumption for unlevered U.S. core property is 6.25 percent, though MassPRIM believes it can add additional return through manager selection and capital-structuring decisions. | <urn:uuid:cd5bbc56-51c1-4596-8ada-9de2197f6f5e> | CC-MAIN-2023-40 | https://irei.com/news/massprim-to-vote-on-rfp-for-real-estate-consultant/ | 2023-09-26T04:45:56Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.939629 | 273 |
It’s easier to paint a tree, than to grow a tree, I think now. As I grow older and impatiently wait for the maple I planted three years ago to grow more. My paintings of trees hold the memories of trees of childhood and long ago.
Here’s some of my favorite tree paintings…each one has a special meaning in my childhood. continue reading | <urn:uuid:d9b7bfd1-9bad-45da-8f8f-1a4e78c534cd> | CC-MAIN-2023-40 | https://irenerowley.com/blog/2018/09/ | 2023-09-26T04:41:29Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.963365 | 79 |
Graduating Students Honored with Director’s Awards for Excellence
Four graduating students of the San José State University School of Information’s Master of Library and Information Science degree program are starting their post-graduate school life with a new award on their résumés. Kristen Chua, Rachel Fleming, Devon Cahill, and Charlie Harmon have all received Director’s Awards for Excellence. These awards are given out to well-deserving students who are nominated or self-nominated for their academic or professional achievements.
Director’s Award for Excellence Recipients
- Director’s Award for Excellence in International Contribution: Kristen Chua
- Director’s Award for Excellence in Innovation: Kristen Chua
- Director’s Award for Excellence in Building Community: Rachel Fleming
- Director’s Award for Excellence in Diversity and Inclusion: Devon Cahill
- Director’s Award for Excellence in Intellectual Inquiry: Charlie Harmon
Chua is the dual winner of the Director’s Award for Excellence in International Contribution and the Director’s Award for Excellence in Innovation. She shares about her grad school experience: “I’ve been lucky to finish up my master’s degree on a high note and feel more prepared to pursue other educational and professional development opportunities.”
For Chua, one of the highlights of her learning journey is working with Dr. Ghosh in the ICAAN Lab. “When my research paper with the ICANN Lab was published in a peer reviewed publication, it was very exciting because the fruit of our team’s research and labor contributed to the scholarly record,” she elaborates. Chua plans to continue collaborating in the field of informatics and information science. “I’m compiling a reading list and looking for a community of information science or informatics researchers and practitioners that I can grow and share ideas with.”
Fleming, the recipient of the Director’s Award for Excellence in Building Community has “demonstrated an ability to work collaboratively and strengthen communities of all types.” On receiving the award, she states, “Building community is something I hope to continue for the entirety of my life. We are stronger, more innovative and more effective in strong connected communities than in siloed positions.”
Throughout her time in the MLIS program, she participated in four internships. However, Fleming notes that at her last internship at CSUF’s Research Center “it all became clear, this is what I was meant to do, this is what I enjoy doing. I’ve never felt such a clear sense of purpose and direction.” Fleming’s career goals are to work as an academic librarian and eventually earn her PhD.
Cahill, the recipient of the Director’s Award for Excellence in Diversity and Inclusion, has shown “outstanding leadership through a work or community service innovation, internship or scholarly research effort benefiting an economically, linguistically or otherwise diverse service population.”
Harmon has won the Director’s Award for Excellence in Intellectual Inquiry for their “intellectual curiosity above and beyond their required coursework, a passion for learning, and continued learning.”
All four of the Director’s Award for Excellence winners received a gift certificate and citation. | <urn:uuid:59d13c9e-9829-4c46-b64d-bf65ebec1c94> | CC-MAIN-2023-40 | https://ischool.sjsu.edu/news/graduating-students-honored-directors-awards-excellence | 2023-09-26T06:23:38Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.944161 | 697 |
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Linapacan is slowly attracting more tourists, especially after Daily News Dig listed it as having one of the clearest waters in the world, excellent for the beautiful coral reefs and snorkeling.
Although most tourists will only visit the touristy and known places like El Nido and Coron, there are plenty of underrated and undiscovered islands in between, one of which is Linapacan.
The municipality of Linapacan has 52 islands included in its official region, but we counted there are 82 paradise beach islands to explore along our regular boat tours between Sibaltan and Coron.
Also known as Little Maosonon Island, you can actually see a little resemblance between Magransing and Maosonon.
Sure, the waters were still clear. But the island is famous for its long sand bar, which looks really amazing. The sand bar is quite narrow that you can see the waves meeting from both sides. It is better to go there when it is low tide so the sand overlaps the water.
It will take roughly 30 minutes from Maosonon Island to get to Magransing Island. There are no houses on the island but you can find a bamboo nipa hut where the man who collects money for the environmental fee waits. It is better to bring some food, drinks and beers before going there because it will take a few hours to reach the town of San Miguel, where there are regular stores.
Most people do not know about this island if they take a fast craft ferry from El Nido to Coron or vice versa. This is just one of the many islands they would miss along the way. For sure on your next trip, you do not want to miss this untarnished island, which you can have for yourselves because it is away from the crowds!
If you are visiting Philippines and want to experience pristine tropical islands, Palawan is the PERFECT place for you. To get here, you can join or book one of our private custom Palawan boat tours between El Nido and Coron, or a local Coron tour. Tons of paradise beach islands to see along the way, excellent snorkeling in crystal clear waters, caves to explore, Spanish fortress and much more. Completely off the beaten path!
This is a must to do!!Super ultimate tour is the best with Kayangan and barracuda lake, twin lagoons (my favorite), coral garden (blue fabulous coral) were the best. It’s really worth it to pay for private tour (3500 to 4000 PHP). You will also have to pay for entrance fees (150 to 200PHP by location) and eventually shopping at the market - must do (count 300 for 2 for fish, pork, fruits and vegetables, water).
I was looking for a personalized excursion to the beautiful Gulf of Bacuit.Seeing the comments, I contacted Mel.Very responsive, very efficient and perfect organization.The flight attendants were very friendly and very helpful.And I'm not even talking about the meal on board...a marvel.In all fairness, this excursion will remain an excellent memory and I cannot recommend Mel and his team highly enough.A big thank-you.
This tour went well above all our expectations! I couldn't recommend this enough! The boat crew, captain and tour guide were nothing but amazing, everyone was so kind, helpful and friendly. The crew knew the best spots to visit that weren't overcrowded with tourists, 3 times we were lucky enough to have whole islands to ourselves! It was my partner's birthday while away and everything went above and beyond, bonfire, cake, birthday card, singing and celebrating with us.If you love camping this is definitely a tout you should do, it has been the highlight of our trip!!
We booked a 4 days/3 nights private boat trip from Coron to Sibaltan. The organization went very well from the beginning, the owner answered to all my questions, and we were able to choose which islands to visit and where to sleep. The first night we slept in a bungalow in Banana Island, the second we camped in Araw beach and the last we slept in a seafront bungalow builded on a tree in Pical on Iloc Island.The islands in that area are the most beautiful islands I have ever seen, with clear water, lots of coral reef and fishes to see, white sand and almost deserted. The crew was very friendly and polite and they organize every single meal and for camping they give you a tent which was just perfect! This was our highlight in our 2 weeks in the Philippines and I wish I had booked a longer trip. A private trip gives you the freedom to decide where and when to go. | <urn:uuid:36a3ca72-ed0c-4e8b-983b-f914f76ba9a5> | CC-MAIN-2023-40 | https://islandhoppinginthephilippines.com/palawan/boat-trips-tours/magransing/ | 2023-09-26T06:12:48Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.971275 | 977 |
We provide our clients with a full background check - due diligence - skip trace services and cyber background checks aimed at verifying the information about people and corporations. We also offer cyber background checks.
Very often our clients need to locate offshore assets, conduct a due diligence of business partners, do cyber background checks to identify an internet friend, and skip trace debtor or scammers.
Sometimes, a case requires an adviced background check which includes also the verification of the criminal records of the target of the investigation.
All information is collected and provided in string observance of the law. Such Information is not collected from Consumer Credit Agencies. In the United States of America, such laws include Drivers' Privacy Protection Act and related state laws (DPPA), the Gramm-Leach-Bliley Act (GLBA) and the Fair Credit Reporting Act (15 U.S.C. § 1681, et seq.) ("FCRA").
The information and reports provided by ISOG are not credit reports and may not be used as a factor in establishing a consumer's eligibility for credit, insurance, employment, child support capability or another purpose identified under the Fair Credit Reporting Act (FCRA). ISOG reports are only provided for permissible purposes such as skip tracing, fraud investigations, and other criminal investigations among others. | <urn:uuid:8eb88d13-8efe-4486-8d79-8c069707327d> | CC-MAIN-2023-40 | https://isog.org/background-check-due-diligence-skip-trace-services/ | 2023-09-26T06:13:02Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.917432 | 264 |
Alum Sean Andersson named Mechanical Engineering Department chair at Boston University
Alum Sean Andersson (ECE Ph.D. 2003) has been named chair of the Boston University Mechanical Engineering Department. He had been serving as interim chair of the department since July 2022, and has been on the university's faculty since 2006.
A former student of Professor P. S. Krishnaprasad (ECE/ISR), Andersson has conducted research in advanced systems and control theory with applications in scanning probe microscopy, dynamics in molecular systems, and robotics operating in real-world environments. In addition to his active research program, since 2019 Andersson has served as director of the Master of Science program in Robotics & Autonomous Systems and is helping to create a new Robotics & Autonomous Systems Teaching and Innovation Center.
“I am extremely excited to build upon the strengths of our department, including, of course, our amazing faculty and their passion for their research and for teaching,” Andersson said. “I am confident that working together we can continue, and even accelerate, our upward trajectory.”
A senior member of the Institute of Electrical and Electronics Engineers (IEEE), Andersson has served as associate editor for several journals, including IEEE Transactions on Automatic Control and the Society for Industrial and Applied Mathematics’ SIAM Journal on Control and Optimization. He has advised 15 PhD students and earned the BU College of Engineering Service Award in 2019.
--ISR thanks Boston University for this story. Read the original here.
Published June 19, 2023 | <urn:uuid:3f096e8d-eeec-49bc-b327-e8f5e202d80e> | CC-MAIN-2023-40 | https://isr.umd.edu/news/story/alum-sean-andersson-named-mechanical-engineering-department-chair-at-boston-university | 2023-09-26T06:17:46Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.965453 | 323 |
3 ISN and 1 ICA-rider suffering fractures
Crashes and serious injuries: “You just do what you have to”
Just another “obstacle to be overcome”
You’re a professional cyclist.
You crash and suffer injuries that horrify onlookers, and which many consider possibly career-ending. Do you crawl into your personal cave and feel sorry for yourself? Do you start thinking of other ways to earn a living and support your family?
No, you don’t, if you are a rider on the Israel Start-Up Nation Team. Dark moments? Thoughts of a career end? Worries about the future? It’s more like: Oh, another injury, very inconvenient, let’s get this thing healed up and get me back on the bike.
And what else do they have in common? Strong family support. They all specifically say how important that is to their recovery, both physically and emotionally.
Greipel, Hermans, Sutherland and Ávila
Three of our veteran riders are currently out with serious injuries suffered in various crashes: Rory Sutherland, Ben Hermans and Andre Greipel. Although all three crashes occurred under totally different circumstances, the three riders all know how to put it behind them and move forward.
Rory was the first one, crashing his rented E-scooter after a team dinner at training camp in Tel Aviv in December, the day before the team presentation. He suffered a fractured femur.
Ben made it two-plus stages into the season, crashing on the third stage of the Tour Down Under, his first big highlight of the season. He came out of it with a complex shoulder fracture, a collarbone fracture, and three broken ribs.
Andre had a training crash in February on home roads after successfully completing the TDU and two other races in Australia. He both fractured and dislocated his left shoulder.
Rory is already back on the bike and on the road, hoping to be back racing in May. Ben and Andre should be back training on the road in April.
Many of us would find it hard to cope with an injury which might conceivably end our career, especially when we are at an age where many of our colleagues are a decade or more younger. We might despair.
Not our guys.
“For me it’s not difficult to just do what I need to do” –Ben. “It’s an obstacle that can be overcome” – Rory. “Missing the Classics is more painful than the shoulder” – Andre.
Rory had the added difficulty of having newly signed with the team, and then suffering such a major injury before even riding one race day. Surely that is stressful? “You can’t change what has happened but you can change the trajectory. I’m incredibly driven to pay back the team for their help and trust in supporting me through the injury the way they have. There has been no pressure and so much support.”
For Ben and Andre, the additional difficulty is missing their first goals of the year, their beloved Spring Classics.
“It’s quite hard to see other riders racing now and get rewarded for the efforts they did in November, December and January,” Ben said. “Two of my favorite races and goals of the year passed already and it’s still a long way before I can race again. I will miss a lot of good races and I try not to think too much about which races I am missing.”
“It’s not easy to stay optimistic right now, since I would have liked to have started the Classics, and I know how long the rehab will be,” Andre admitted.
Rory is the eldest of the three, but says his age does not hinder his comeback. In fact, it has actually been beneficial. “At 38 years old, I have the capabilities to deal with it. Someone who is 24 years old, with all the ambition and excitement still to come might have a harder time. I have the experience to deal with complications.”
“I honestly have nothing to lose and in the end this has given me a different outlook and perspective on the sport.”
The first week after surgery was harder than the first days after the crash for Ben. “In those first days I actually wasn’t aware of how long I would be out of competition. For sure the first week after the surgery was the hardest, with pain, but also mentally, as I knew it would take long time to get back to a good level.”
At first, it was feared that Rory’s injury might be career-ending. That never really concerned him, he said, although of course he cares about continuing his career. “I have had the benefit of a long and fruitful career. I’ve achieved what I wanted in the sport, so it’s not like I’m missing some piece. I think that creates more calm about it, which allows me to recover better that I would have with stress and angst. I have always been an ‘it is what it is’ person.”
Despite the seriousness of his fractures, Ben never for a moment thought of the end of his career. “No. Not really. Nowadays the medical sector can fix many severe problems and my legs are 100%.”
And perhaps the most important aspect for not only their recovery but also their mental health is found at home with the family.
“I need the help of my family quite a lot for the moment as I can do almost nothing. But they are not stressed. We have been in this position before and we know what to do to come back,” said Ben, who also recently shared the happy news that they are expecting their second child this summer.
“My family of course supports me fully. And when I am down, the bring me to smiling again,” said Andre.
According to Rory, “without my family and support network I have no idea where I would be right now. My wife has taken on a huge load without complaining, not even once. We just get on with it and deal with it.”
Rory: Things are looking quite good now, and he is on the bike “20 hours a week now and building!”
Ben: He is back on the bike – on the rollers, at any rate. He is finally allowed to use both arms again, and will immediately start physio to stabilize the shoulders. If all goes well he should be out on the road training in a few weeks.
Andre: Andre still has to be patient for a few weeks. “Until 27.03 all remains the same – I must continue to keep my arm quiet. As of 27.03, though, I can start actively working on the muscle, hopefully I can then ride outside again.”
And unfortunately we have another one to add to the list: Edwin Avila of the Israel Cycling Academy Continental team. A crash in the Tour of Rwanda left him with a severe concussion and fractured wrist. “Right now I can’t do anything for another 5 weeks or so, the doctor said, I must rest completely.”
Text: Susan Westemeyer | <urn:uuid:db1cdf1a-aa47-4242-8f94-e08e81a749e9> | CC-MAIN-2023-40 | https://israelpremiertech.com/greipel-hermans-sutherland-and-avila-injury-update-you-just-do-what-you-have-to/ | 2023-09-26T07:00:50Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.977661 | 1,556 |
Once again, Israel Start-Up Nation was in the mix for the stage win in the Giro d’Italia as Davide Cimolai sprinted to second place on stage 7. This was the fourth podium place and the seventh Top 10 for the team in the race so far.
With a flat profile and a strong headwind for the majority of the day, it was no surprise to see only three riders interested in joining the early breakaway. The peloton kept the trio in check all day, never letting the gap exceed four minutes, and, as expected, it all came down to a sprint at the end.
Taking place in the backyard of the team’s sponsor, Vini Fantini, the ISN guys were eager to put on a strong performance today. Additionally, Sports Director Nicki Sørensen was hoping for a gift in the shape of a good result on his 46-birthday.
In the final kilometers of the stage, Cimolai did very well to get on the right wheels, ultimately finding his way to the wheel of Caleb Ewan (Lotto-Soudal) who took the win, while Cimolai gritted his teeth and hung on for second place on the line.
Team leader Dan Martin finished safely in the bunch, keeping his top-10 place overall ahead of tomorrow’s mountainous stage.
Davide Cimolai: “This almost feels like a victory. It’s another second place but today I’m happy because I did my best and when you do your best, you’ve got to be happy. After the last uphill part, I took the wheel of Ewan and I just did my best to stay there. It’s hard to beat him when he’s on a good day like today but we will try again for sure!” | <urn:uuid:112ed154-ef30-4aae-afb8-ebd58dc7cbc4> | CC-MAIN-2023-40 | https://israelpremiertech.com/second-place-for-cimolai-on-stage-7-of-giro-ditalia/ | 2023-09-26T05:15:34Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.970213 | 390 |
ITELENCE nominated for a Top Software Services Provider award!
ITELENCE is on a prestigious short-list of six companies nominated for the Top Software Services Provider at the 11th CEE Business Services Summit & Awards organized by European Business Services Association. The annual event is one of the most premier meetings for Business Services Sector and celebrates the best companies across Central and Eastern Europe region.
The award will be decided by the distinguished Jury members who will meet in Warsaw for final vote.
“We are delighted with the recognition from the organizer and jury and commit ourselves to maintaining our high quality service standards” says Szymon Stadnik, CEO, ITELENCE.
Join the event!
Wednesday-Thursday March 8-9, 2023 | <urn:uuid:d956322a-31b3-46bb-afaf-865d759efddc> | CC-MAIN-2023-40 | https://itelence.com/itelence-nominated-for-a-top-software-services-provider-award/ | 2023-09-26T05:30:31Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.913676 | 153 |
Iceland -isn’t all covered in ice!
For something totally different in a holiday head off to Iceland – you’ll feel like you’ve landed on the moon. With the interesting landscapes, rugged volcanic mountains, large open plains and thermal pools – you’ve landed in Iceland. Its capital Reykjavik leads the way for tourist to explore this amazing place.
Our arrival was met with amazement at the landscape and my children all thought we had landed on the moon. Our first Icelandic experience was on our Iceland Air flight from Amsterdam , initial thoughts were they are a little ‘ frosty ‘ but when you get to talk to the Icelandic people , they are warm and friendly . The hour drive from the airport got us to our hotel in Reykjavik just before dark – and it was only 3.30pm. We got settled into our hotel the Radisson Blu and decided to explore the area around the hotel, however at 5.00pm it was -15 degrees and pitch dark …. Our first stop was to join a long line of people waiting outside the worlds famous Icelandic Hot Dog stand… if all these people are waiting it must be good .. During the 45 minute wait, more and more people kept arriving to line up… some even in taxis. The hot dogs were quite amazing, very tasty and very different… one with the lot included dried Tuna , dried onions , a sauce we still don’t know was it was and mustard like we’ve never tasted.
Our next introduction into Icelandic life was the most popular tour – The Golden Circle. This you get to see 3 of Iceland’s most extraordinary natural wonders – Guillfoss, Gyesir & Pingvellir all in one amazing day.
Starting out in the dark at 9.00am you head off to Gullfoss – a spectacular rainbow tinged double cascade that falls 32m down a narrow ravine, however in January this was frozen solid in the -16 degrees and cold like we’ve never felt before. 10 kms away is Geysir, after which all spouting hot springs are named .The Great Geysir is the main attraction that spouts every six minutes, when it spouts into an impressive 15m – 30m plume.
Then it’s off to Pingvellir National Park, one of Iceland’s most important historical sites. The Vikings established the world’s first democratic parliament here in 930AD. It also has a superb natural setting on the edge of an immense rift caused by the separating North American & Eurasian tectonic plates. Pingvillr was made a Unesco World Heritage Site in 2004.
As Reykjavik is the world’s most northerly capital, it offers a combination of small town experience and hip and trendy escape. Nature adds an extra dimension with the rugged snow covered mountains that fringe the city. Reykjavik is an easy city to explore , with its streets easily marked and getting your baring’s are all very easy , it has lots to offer with some of the most interesting shopping, trendy cafes and very hip bars , this is not a city that sleeps .
Add this to your list of MUST SEE PLACES so for more information or how to arrange your Iceland Experience – call me. | <urn:uuid:d1955ac2-42fc-4098-b27c-fac5a5e1053a> | CC-MAIN-2023-40 | https://itravel-au.com/blog/iceland-isnt-all-covered-in-ice/ | 2023-09-26T06:02:33Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.956859 | 691 |
In August 2018, I had the privilege of attending a Kuala Lumpur Famil hosted by Malaysia Airlines and Viva Holidays.
We flew Malaysia Airlines in Economy on the way over and Business Class on the way back. I have always found economy very comfortable with Malaysia Airlines, with great service and great entertainment. As we had Trent from Malaysia Airlines with us, group check-in at the Business counter was quick and efficient. We were able to use the newly improved Golden Lounge in Kuala Lumpur before our return flight. There was an aircraft change at the last minute, so the business class wasn’t the same standard as on the A380 which we had a peek at on the way over. After a bit of a delay for take-off, the meal (snack) service was served, almost the best Satay Chicken and Beef I have tasted. Service throughout was also great, as was entertainment, with a good sleep followed in the fully flat bed.
We stayed 2 nights at the Berjaya Times Square Hotel which is in a great location, with fabulous facilities. Very spacious rooms and we were spoiled with access to Club Lounge, which served a fabulous breakfast with great service and lovely atmosphere. I even had time to check out the lovely pool area, probably one of the bigger pools in KL I have seen and had time for a quick swim. The last night we stayed at the Melia. The rooms here were very stylish, although smaller, and again, we had access to Club Lounge breakfast. This was nice but not run as efficiently as the Berjaya. The Melia has a lovely pool area, complete with a great bar/restaurant and relaxing lounge area, which we had time to make use of.
Our hosted tours (Viva Holidays) included an Urban Adventure Food experience, a City sights tour and a visit to Kuala Selangor town where we interacted with forest monkeys, went to a local restaurant for dinner, then proceeded to Kampung Kuantan to board small boats to see the fascinating Fireflies within the mangrove swamp (in the darkness they look like flashing Christmas lights).
The walking food tour was a highlight for me and a must do. We had a great guide who was very informative. We learnt about the history and culture of KL and sampled some great food. A local food stall that we stopped at had the best curry puffs I have ever tasted. I would definitely recommend this to clients, but there is a fair amount of walking involved in the heat, and while there were plenty of refreshment stops, it might not suit everybody. | <urn:uuid:4e4d6fd9-55e3-452d-9ce1-e8ec86ee37f7> | CC-MAIN-2023-40 | https://itravel-au.com/blog/kuala-lumpur-famil/ | 2023-09-26T05:03:15Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.980317 | 538 |
I was lucky enough to win an incentive trip to South Africa. It was a whirlwind trip where we experienced game drives, tours, dining and soaked in African experiences.
I flew Qantas there and back. I went Premium Economy on the way over and Business on the way back. Premium Economy was very comfortable with lovely service, decent meals and great entertainment system. Business class was very nice with great service. There were plenty of snacks you could order at any time, comfy Qantas Pyjamas and a flat-bed to sleep in! Lots of space for storage and very comfy in business class! Our internal flights with South African airways were also very comfortable, great food and customer service.
We stayed at 5 different Safari Lodges, most of which were fabulous, including Imbali Safari Lodge, Black Rhino Lodge and Karongwe River Lodge. Each one was unique and all games drives that we experienced were fantastic, spotting “The Big Five” in one day. We also spent 2 nights in Cape Town at the Cape Milner Hotel, had a great day exploring the area and a fantastic lunch down by the waterfront.
This is my third trip to Africa, and it won’t be the last! I believe everybody must get to Africa at least once in their life. Every experience is truly wonderful. | <urn:uuid:1de49f4d-6b2c-4ea4-9750-81578074388b> | CC-MAIN-2023-40 | https://itravel-au.com/blog/south-africa-2018/ | 2023-09-26T04:58:46Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.982089 | 280 |
How to Clean Headlights with Brassoby Alibaster Smith
Brasso is a metal polish, but it is not restricted to use on wheels. Brasso polish will remove fine scratches-like those found on old headlights. Over time, many vehicle headlights develop a "haze" on them from years of being exposed to the sun and other elements. If you want to restore the lights to their original clarity, you'll need to buff out those scratches.
Apply the Brasso to the lens of the headlight assembly.
Work the Brasso into the headlights with an orbital buffer. Start out wiping the Brasso across the headlight with the power off. Then, turn the power onto the lowest setting and allow the buffer to do the work. The Brasso will polish the headlight lens and remove the haze very quickly.
Wipe the headlight lens with a clean, lint-free towel.
- Auto Body Repair Technology - 5th Edition; James E. Duffy, Cengage Learning; 2009
- Automotive Tools Manual: Guide to Buying and Using Automotive Tools; Thomson Delmar Learning; 1999
Things You'll Need
- Orbital buffer
- Lint-free towel
I am a Registered Financial Consultant with 6 years experience in the financial services industry. I am trained in the financial planning process, with an emphasis in life insurance and annuity contracts. I have written for Demand Studios since 2009. | <urn:uuid:e7accd06-f1d1-4682-8424-e9010962a43d> | CC-MAIN-2023-40 | https://itstillruns.com/clean-headlights-brasso-5636980.html | 2023-09-26T06:08:27Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.898379 | 311 |
On the occasion of the death of Pope Benedict XVI, we remembered his many services to which he owed the Croatian people, including his visit to our homeland in 2011. Saying goodbye to him, our duty requires us to gratefully remember and highlight his interest in our Blessed Ivan Merz and to emphasize his special and great recognition of the holiness of our Blessed One when he included him among the 18 greatest saints of the Catholic Church who especially worshiped the Eucharist.
Even as Cardinal Joseph Ratzinger, he met Ivan Merz. He was a member of the cardinal commission that approves beatifications and canonizations, so in that capacity, he read the entire Position of blessed Merz, i.e. the document that proves that a certain candidate for the altar had and performed heroic virtues. The position of bl. Merz is an extensive biography, and it has over a thousand pages. When Cardinal Ratzinger read it, he was delighted with Blessed Merz, and not only his familiarity with and interest in him, but also his veneration, which manifested itself when he was elected pope, dated from that time. In the following, we will provide information about all his interventions where the interest of Pope Benedict XVI for our Blessed One was manifested.
Bl. I. Merz at the Bishops’ Synod in the Vatican
The 11th regular Synod of Bishops was held in the Vatican in October 2005, which was devoted to the Eucharist. Bishop Franjo Komarica of Banjo Luka participated as a delegate of the Bishops’ Conference of Bosnia and Herzegovina. In front of numerous bishops from all over the world, Bishop Komarica spoke about the example of the Eucharistic life of Blessed Ivan Merz. Pope Benedict XVI, who was elected as Peter’s successor that year, also participated in the Synod.
Bishop Komarica gave his speech in front of the Pope and numerous bishops from all over the world on October 12, 2005, and he began it as follows:
“Holy Father, honorable Synodal Fathers! In my address, I would like to rely first on number 76 of the working document of the Synod “Instrumentum laboris-a”, where it is warned about the necessity “to encourage knowledge of the lives of saints and blessed who were models of spirituality and Eucharistic life”. Among the names of a large number of saints and blessed from various centuries listed in the working document of the Synod, starting with Ignatius of Antioch and Augustine, then Benedict, Francis of Assisi, Thomas Aquinas, and Mother Teresa of Calcutta, there is the name of a young layman, blessed Ivan Merz. Not without reason. Due to its topicality, I want to give you some information about it.”
Then Bishop Komarica presented basic biographical information about Blessed Ivan Merz, whom Pope John Paul II. two years later, that is, on June 22, 2003, he was declared blessed in Banja Luka. Among others, Bishop Komarica said: “Based on his multinational origin, his intellectual education, his spiritual formation, and his apostolic activity, Blessed Ivan Merz connects in his person a whole series of European nations and countries: in addition to BiH and Croatia, also the Czech Republic, Germany, Hungary, Austria, France, and Italy. A true Christian European, highly educated in Vienna and Paris, who managed to unite science and religion. Forty years before II. During the Vatican Council, he practiced and promoted much of the Council’s teaching on liturgy and the role of the laity in the Church. The main characteristic of his Eucharistic devotion was his living faith in Christ’s presence in the Eucharist.”
In the second part of his speech, Bishop Komarica informed the Synodal Fathers about the severe suffering and consequences of the war that hit his diocese, where as many as 95% of the faithful were exiled and one-fifth of the priests were killed. When Bishop Komarica finished his presentation, the synod hall erupted into a big round of applause, which is not normally customary and it is a real rarity that speakers are applauded after a presentation.
After the presentation, many bishops approached Bishop Komarica, congratulated him on a nice presentation, and thanked him for introducing them to Blessed Ivan Merza and his current affairs, as well as the situation in Bosnia and Herzegovina. Some told him that his performance with its content was a true refreshment and revelation. Many bishops immediately acquired the biography of Blessed Ivan Merz in Italian, which was published by the editorial office of the Vatican newspaper L’Osservatore Romano.
Pope Benedict XVI was interested in Blessed Ivan Merz during the Synod
During the session of the Synod, Pope Benedict XVI received the Synodal Fathers in groups in a special audience. When he saw Bishop Komarica, he immediately said with joy: “We have Blessed Ivan Merz!” Shall we declare him a saint?! How is his cause for canonization going?” After Bishop Komarica briefly told the Holy Father what was being done to promote the knowledge and veneration of the new Blessed One, the Pope encouraged him with words to continue working in that direction. Bl. Ivan Merz is one of the few God-pleasing people who attracted the attention of the Holy Father at the Bishops’ Synod.
Pope Benedict XVI prays to Blessed Ivan Merz
From February 23 to 28, 2006, the bishops of Bosnia and Herzegovina were in Rome on an ad limin visit, which includes a visit to the Holy Father and a personal meeting with him. Thus, on the first day of the campaign, on Thursday, February 23, 2006, Bishop Franjo Komarica was admitted to an audience with Pope Benedict XVI.
At the end of the official conversation, the Holy Father surprised him with the question: “How is the veneration of blessed Ivan Merz spreading?” The bishop, pleasantly surprised by this question, thanked the Holy Father for taking an interest in our youngest Blessed, and the Pope immediately added: “Of course, Ivan Merz is truly an extraordinary person. I know him well and I pray to him!”
Bishop Komarica then informed the Holy Father about the details of how Blessed John is venerated in the Banja Luka diocese. He said that the feast of Blessed John will be solemnly celebrated on May 10 this year in the Banja Luka Cathedral, where a large gathering of believers is expected. The Pope replied: “Very well, I’m glad and I’m already giving my blessing to everyone who will gather that day in your cathedral to celebrate the feast of Blessed Ivan Merz.”
Blessed Ivan Merz in the latest papal document on the Eucharist
On March 13, 2007, the first Apostolic Exhortation of Pope Benedict XVI “Sacramentum Caritatis” was presented to the public in the Vatican, during the Eucharist, the source and pinnacle of the Church’s life and mission. At the beginning of the conclusion of the petition, in no. 94, the Pope mentions Blessed Ivan Merz as the only Croat among the chosen 18 great saints from the history of the Catholic Church as a model of the worship of the Eucharist. Here is that part from this important papal document:
“Dear brothers and sisters, the Eucharist stands at the source of every form of holiness and each of us is called to the fullness of life in the Holy Spirit. How many saints made their lives authentic thanks to their Eucharistic devotion! From St. Ignatius of Antioch to St. Augustine, from St. Anthony the Abbot to St. Benedict, from St. Francis of Assisi to St. Thomas Aquinas, from St. Clare of Assisi to St. Catherine of Siena, from St. Pasquale Baylon to St. Peter Julian Eymard, from St. Alfonso M. Liguori to Blessed Charles Foucauld, from St. Ivan M. Vianney to St. Therese of Lisieux, from St. Pius of Pietrelcina to Blessed Teresa of Calcutta, from Blessed Piergiorgio Frassati to Blessed Ivan Merz, to mention only a few of the many names, holiness always found its center in the sacrament of the Eucharist.
The mention of Blessed John Merz in this Papal document is a great recognition of the holiness of Blessed John, but also a recognition of the Church in Croatia that has such a well-pleaser of God who can represent it before the whole world in this chosen company of great saints, worshipers of the Eucharist. But it is also an encouragement to all Croatian believers to get to know our Blessed One better by reading his writings.
June 26, 2007
Pope Benedict XVI is again interested in Blessed Ivan Merz
and sends his blessing to his worshippers
Banja Luka Bishop Franjo Komarica stayed in Rome from June 19 to 21, 2007. During the general audience, on Wednesday, June 20, he met with Pope Benedict XVI, who on that occasion again showed interest in the Croatian Blessed Ivan Merz.
Bishop Komarica presented the Pope with a monograph on the sufferings of the Banja Luka diocese and its Croatian believers, 95% of whom were exiled from their homes and land. This time too, the Pope was interested in Blessed Ivan Merz and expressed his joy by saying: “I gladly bless you, your priests, monks and nuns and all the members of your suffering diocese as well as all the worshipers of blessed Ivan Merz”.
March 5, 2008
Pope Benedict XVI again about Blessed Ivan Merz
Banja Luka Bishop Franjo Komarica met with the Holy Father Benedict XVI at the end of the general audience on Wednesday, March 5, 2008. On that occasion, the Pope was the first to mention Blessed Ivan Merz again and added that he prays to him every day. Here is what Bishop Franjo Komarica told us about his reunion: “When it was my turn to approach the Pope, he exclaimed with a smiling face and outstretched arms towards me in German: “Well, Bishop Komarica, you have the great Blessed One with you, the truly great Blessed Ivan Merz!” I answered him smiling: “Yes, Holy Father, we hope and pray that he will be declared a saint as soon as possible.” The Pope replied to that: “I hope so too I pray to him every day!”
June 18, 2008
Pope Benedict XVI recalled the 5th anniversary of the beatification of Ivan Merz
On Wednesday, June 18, 2008, at the general audience, the Holy Father addressed the Croatian pilgrims in the Croatian language, in which he mentioned the fifth anniversary of the beatification of Ivan Merz and encouraged the faithful to follow his example of faith and piety. Here are the Pope’s words: “I send a special greeting to the Croatian pilgrims. On the upcoming fifth anniversary of the beatification of Ivan Merz, I encourage you to confirm your faith daily with piety and acts of love. Praised Jesus and Mary!”
June 22, 2008
Telegram from Pope Benedict XVI for the 5th anniversary of the beatification of Ivan Merz
For the celebration of the fifth anniversary of the beatification of Blessed Ivan Merz, which took place in Banja Luka on June 22, 2008, the Holy Father Benedict XVI sent a congratulatory telegram that was read at the beginning of the solemn Holy Mass on Petrićevca, led by the Papal Apostolic Nuncio Alessandro D’ Errico. In the telegram that he sent through his State Secretary, the Holy Father expresses his strong desire that the figure of Blessed Ivan Merz and his life “permanently inspire all Christian people.” The telegram reads in its entirety:
“On the occasion of the fifth anniversary of the beatification of Ivan Merz, the Holy Father Benedict XVI sends you his sincere congratulations, mentioning this dear witness of ardent love for Christ, an authentic model of Christian virtues and a busy promoter of evangelical values. His Holiness wishes from the bottom of his heart that his image and life permanently inspire all Christian people, and in a special way young lay people, that guided by enthusiasm for God and responsibility for society, always confirm their faith with deeds. Using the intercession of the Blessed, the Successor of Peter is happy to bestow the requested apostolic blessing on you, the participants of this significant celebration, and on all those who will generously contribute and help the restoration of this local Church.”
Zagreb, June 4, 2011.
Pope Benedict XVI spoke about Blessed I. Merz at a meeting with young people
The inclusion of Blessed Ivan Merz in the document on the Eucharist Sacramentum Caritatis back in 2007 was the most important act of Pope Benedict in recognizing the sanctity of our Blessed One, by which he indirectly already canonized him, placing him alongside the great saints in the history of the Church. However, the second most important intervention of Pope Benedict about our Blessed One was during his visit to Croatia in 2011, when he spoke about Blessed Ivan Merz at a meeting with young people in Ban Jelačić Square on Saturday, June 4, 2007.
“How many young saints and saints in the great wing of the Church! But here, in Croatia, you and I fix our thoughts on blessed Ivan Merz. A great young man, fully involved in social life, who is embarking on the university path. In the years of the First World War, he is faced with destruction and death, but all these shapes and builds him, allowing him to overcome moments of crisis and spiritual struggle. John’s faith became so strong that he dedicated himself to the study of the liturgy and began a strong apostolate among the youth themselves. He discovers the beauty of the Catholic faith and realizes that his vocation in life is to live, and live friendship with Christ. How many wonderful acts of love and kindness fill his path. He died on May 10, 1928, at the age of only 32, after several months of illness, presenting his life for the Church and young people. That young life, given out of love, carries the fragrance of Christ, and it is a call to everyone not to be afraid to entrust ourselves to the Lord.”
Pope Benedict XVI wanted to visit the grave of Blessed Ivan Merz
but was prevented from doing so
During his visit to Croatia in June 2011, Pope Benedict had the intention and desire to visit the grave of Blessed Ivan Merz. As soon as it was announced to the public that he was coming to Croatia, he let the organizers of his trip know that his visit would include a visit to the grave of Blessed Ivan Merz. When the organizers of his trip came to Zagreb two months earlier to determine and organize the details of his visit, they also came to the Basilica of the Sacred Heart of Jesus where they reviewed everything and determined how the visit to the grave of Blessed Merz would take place. The Pope was supposed to visit the Basilica of the Sacred Heart of Jesus and the grave of Blessed Ivan Merz on Saturday afternoon, June 4, 2011, after he meets with representatives of science and the world of culture, heading towards Ban Jelačić Square, where the meeting with young people was held. Ten minutes were enough for him, as planned, to get out of his car and enter the Basilica to the grave of Blessed Merz, to say a short prayer there and continue on his way to Ban Jelačić Square. However, to the great regret of many admirers of Blessed Ivan Merz, this did not happen. Who and for what reason made it impossible for Pope Benedict, who wanted to visit the grave of Blessed Ivan Merz, to be known, but for now this sad information is not yet available to the public. However, this of course does not diminish anything that Pope Benedict has said and done throughout the years of his pontificate for our Croatian Blessed One, with whom he is now in heaven and continues to pray and intercede for the Croatian people. | <urn:uuid:7cfe5b72-bae4-4938-8e34-3ef849095eef> | CC-MAIN-2023-40 | https://ivanmerz.hr/pope-benedict-xvi-and-bl-ivan-merz/ | 2023-09-26T06:52:38Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.97437 | 3,447 |
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A digital Library of Babel
In his 1941 short story "The Library of Babel," Jorges Luis Borges depicts a series of hexagonal rooms, their walls lined with bookshelves. These shelves contain books comprised of every possible combination of letters, spaces, commas, and periods. Some books are filled with nonsense but within the collection lies every literary text ever written, along with multiple permutations of each of these texts. The library's collection comprises all knowledge that is known or will be known.
Borges's vision has been realized in digital form by Jonathan Basile, a writer and coder who has brought the Library of Babel to life. Describing the library, Basile writes:
The Library of Babel is a place for scholars to do research, for artists and writers to seek inspiration, for anyone with curiosity or a sense of humor to reflect on the weirdness of existence - in short, it’s just like any other library. If completed, it would contain every possible combination of 1,312,000 characters, including lower case letters, space, comma, and period. Thus, it would contain every book that ever has been written, and every book that ever could be - including every play, every song, every scientific paper, every legal decision, every constitution, every piece of scripture, and so on. At present it contains all possible pages of 3200 characters, about 104677 books.
We find in Basile's library echoes of the disorientation faced by Borges's suicidal librarians confronted by so much information that books are rendered meaningless. Hovering over the navigation links on the site's front page produces an endless rearranging of letters, shuffling through letter combinations that render recognizable words like "Browse" in meaningless gibberish. Clicking "Random" generates a page of a book from the library, often a sea of letter combinations that seem to have little meaning. These pages offer the option to see an "Anglishized" version that identifies English words among the random letters. Users can also delve into their own hexagonal chambers - or hexes, and the site visualizes walls, shelves, and books to explore. The Reference Hex offers disoriented readers some guidance for making meaning of the library, from basic details on the construction of the library to suggestions for diving into the texts available.
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Your online online dating messages should be entertaining. Don’t use a whole lot of textual content and buzzin language. A humorous firmness can help you choose a message very likely to be reading and liked. For example , when a person comments your appears, she’ll are more interested in yours. Adding an amusing touch on your message should go a long way eventually. When you make your first sales message playful, you can build a relationship with the various other person.
A good message can be one of the most memorable messages to obtain. When you send a compliment, proceeding make your meet feel valued. The warning should be brief. If you’re seeking a date, inquire about their interests, as well. When you are asking these people out, you are going to give them a warm meet. If you’re certainly not interested in someone, they’ll very likely move on to an alternative profile. | <urn:uuid:c9f50b54-b484-4a7f-bcc9-84cc01491d3c> | CC-MAIN-2023-40 | https://jalpakhabar.com/2021/02/22/24349/ | 2023-09-26T04:43:37Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.943311 | 910 |
Customize your JAMA Network experience by selecting one or more topics from the list below.
Pirruccio K, Yoon YM, Ahn J. Fractures in Elderly Americans Associated With Walking Leashed Dogs. JAMA Surg. 2019;154(5):458–459. doi:10.1001/jamasurg.2019.0061
Dog walking is often suggested as an effective modality for improving physical health in elderly Americans.1 Nonetheless, injury risks associated with dog walking remain obscure. Considering that older patients are more vulnerable to fractures owing to falls or axial muscle compression forces inherent to walking motions, a risk-benefit analysis with respect to dog walking as an exercise alternative is essential to minimizing injury risk.2 This study represents a comprehensive, up-to-date investigation into fracture risk in older adults who use leashes when walking dogs.
A retrospective, cross-sectional analysis was performed using the publicly available deidentified National Electronic Injury Surveillance System database of the US Consumer Product Safety Commission, which records product- or activity-related injuries in patients presenting to approximately 100 US hospital emergency departments stratified by size and location. This nationally representative, statistically validated probability sample can be used to derive reliable weighted national estimates and sampling errors for queried injuries.3 Data were acquired from a deidentified, publicly available database. According to the University of Pennsylvania IRB Standard Operating Procedures, institutional review board approval is waived in cases where data are redacted and openly publicly available.
We individually reviewed 1033 free-text narratives in the database of fractures between 2004 and 2017 associated with pet supplies (product code 1715) in patients 65 years or older. We identified 697 total entries, representing 32 624 cases of fall-related fractures in elderly Americans associated with walking leashed dogs. National estimates and 95% CIs were derived using Stata/IC, version 15.1.4 Significance of trends was determined using adjusted Wald tests. Two-sided P values <.05 were considered significant.
The annual number of patients 65 years or older presenting to US emergency departments with fractures associated with walking leashed dogs increased significantly between 2004 (n = 1671; 95% CI, 1111-2232) and 2017 (n = 4396; 95% CI, 3202-5590) (Table 1).
Patient demographic and injury characteristics are detailed in Table 2. Most fractures occurred in women (78.6%; 95% CI, 74.9%-82.2%). Most patients sustained hip fractures (17.3%; 95% CI, 13.8%-20.7%), although the upper extremity was the most frequently fractured region overall (52.1%; 95% CI, 48.1%-56.1%); 28.7% of patients (95% CI, 23.7%-33.8%) required hospital admission.
To our knowledge, this study is the first to identify and characterize leash-dependent dog walking as an activity that imparts a significant and rising injury risk in older adults.
The gravity of this burden is exemplified by the hip being most frequently fractured, because this injury is associated with long-term decreases in quality of life and functional capabilities, as well as mortality rates approaching 30%.5 Combined with the sex disparity in injury burden, older women considering dog ownership must be made aware of this risk.
Clinicians may play a role in identifying at-risk patients and minimizing fracture risk by advocating for preventive actions, such as obedience training to ensure dogs do not lunge while leashed, or suggesting smaller dog breeds for individuals contemplating ownership.6
The study has limitations. Despite the validated nature of the source database, our findings likely underestimate the morbidity associated with elderly Americans walking leashed dogs: only emergency department cases are contained within the National Electronic Injury Surveillance System, and our analysis excluded less severe, nonfracture injuries. Moreover, the database does not include comparative dog sizes, cases requiring operative intervention, or disposition after discharge; future research may clarify the consequences of these variables.
This study draws attention to an activity that can result in significant injury. For older adults—especially those living alone and with decreased bone mineral density—the risks associated with walking leashed dogs merit consideration. Even one such injury could result in a potentially lethal hip fracture, lifelong complications, or loss of independence.
Accepted for Publication: December 9, 2018.
Corresponding Author: Jaimo Ahn, MD, PhD, Department of Orthopaedic Surgery, University of Pennsylvania, 3737 Market St, Philadelphia, PA 19104 (firstname.lastname@example.org).
Published Online: March 6, 2019. doi:10.1001/jamasurg.2019.0061
Author Contributions: Dr Ahn had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: Pirruccio, Ahn.
Acquisition, analysis, or interpretation of data: Pirruccio, Yoon.
Drafting of the manuscript: Pirruccio, Yoon.
Critical revision of the manuscript for important intellectual content: Ahn.
Statistical analysis: All authors.
Administrative, technical, or material support: Ahn.
Supervision: Pirruccio, Ahn.
Conflict of Interest Disclosures: None reported. | <urn:uuid:46d45c54-b59e-4a93-b713-33a0592ffbd6> | CC-MAIN-2023-40 | https://jamanetwork.com/journals/jamasurgery/fullarticle/2727125?guestAccessKey=3eb95062-58ae-4981-a093-57cfc0708647&utm_source=JAMA%20Network&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=030619 | 2023-09-26T06:00:37Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.902078 | 1,113 |
Desert Ships are on tour and to mark their upcoming dates, here’s the Julian Hand directed video for their epic track ‘Skyliner’ produced by Ride’s Mark Gardener.
London trip-tonic three-piece, Desert Ships sound is heavily cinematic. Haunting guitar loops and hypnotic grooves allow the dream-like melodies to weave in and amongst each other, while the three-part vocal harmonies bring a spacey, ambient tint to the eclectic mix.
Comparisons have been drawn with the likes of Brian Jonestown Massacre, The Flaming Lips, Tame Impala and at times, even the rousing film scores of John Barry. Their psychedelic sounds have garnered a passionate following, having toured extensively across the UK and Europe.
In 2012 they released their debut album ‘Doll Skin Flag’ (on iTunes and Spotify) which they recorded with acclaimed producer Mark Gardener (lead singer of seminal 90’s band Ride). Mark described his time working with the band as “a total pleasure, a total trip.”
The band has enjoyed radio airplay from XFM’s John Kennedy, BBC 6 Music’s Steve Lamacq and BBC Radio London Calling’s Gary Crowley.
They receive constant radio play on local radio in the UK, US, Europe and South America. You can listen to Desert Ships atsoundcloud.com/desertships
The band have recently returned to the studio with Gardener and started recording their sophomore album. Notable collaborators include German film director Wim Wenders.
Sat 13th June – Cherry Cola Club, Camden
Fri 19th June – Summer Rock Solstice Festival, Worcestershire
Sun 21st June – Fete De La Musique, Smoking Sod, Lyon, France
Sat 4th July – Hindhead Music Festival, Hampshire
Sat 11th July – Into The Wild Festival, Bucks
Wed 22nd July – 93 Feet East, London | <urn:uuid:bc75fe14-0df2-4d6c-98dd-2571b63ebb1a> | CC-MAIN-2023-40 | https://jammerzine.com/daily-dose-desert-ships-skyliner/ | 2023-09-26T07:02:53Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.946268 | 413 |
We live in a world that pretends to be egalitarian. It is a world where women work long hours at occupations which in the past were considered to be the domain of men. This was not due to the physical demands of these jobs but rather to the excessive hours that need to be dedicated to them. It was taken for granted that women being mothers, were expected to be at home caring for the children; if not all day long, then at least from the time the nursery or daycare closed at 4:00 pm. As such, they weren’t suited for management positions.
Nowadays in a society that proclaims itself to be egalitarian, great strides have been made (although in my opinion, there is still a ways to go to achieve true equality). One of the places in which we are seeing the effects of change is the family unit.
Today, in many homes that I am personally familiar with and from what I hear from my clients, there are a division of duties of one type or another between spouses. Most of the time, this includes dividing the hours for school pick up and afternoon childcare.
Often, on certain days, the husband leaves work early to pick up the kids, enabling the wife to stay later at her job which requires longer hours. On other days, the mother picks up the children from school so that the husband can meet his work schedule .
I believe that the foundation built by the couple jointly raising their children, benefits the children much more than the old standard of one parent being the major caregiver. I know this arrangement is one that motivates parents, and fathers in particular, who desire to maintaining a close, intense and cohesive bond with their children even in the event of a broken marriage.
When a break up occurs, these fathers discover that the legal system is accustomed to establishing the mother as the primary caretaker, with the father only getting visitation rights. This is so, even though the pendulum in Israel is moving towards a concept of joint custody. If we are dealing with a child younger than six years old, we also have the “tender age doctrine” which is the basis of the benchmark for custody to the mother and visitation rights for the father, of only several hours per week.
Unfortunately, many times we see cases where the fathers were intensively involved in raising their children – taking them out of preschool, feeding them meals, diapering them, taking them to extra-curricular activities, attending parent-teacher meetings and the like; yet when the couple starts the divorce process, the wife requests or even demands primary custody.
The legal system, albeit in uncharacteristic tardiness, has undertaken steps toward change, partially due to pressure from father’s rights groups who have banded together for this purpose and partially as a response to an upsurge of requests from parents who want joint custody.
As a consequence of the increase of requests for joint custody, there has been a demand for a proportional division of child support payment obligations. This would reduce the normal amount of support money that the father would need to transfer to the mother for the children because half of the time the children are under his care.
As the saying goes, “With the food comes the appetite”. So too, the equality revolution is gaining momentum and in this case, the support payments will now be calculated based on the income of both spouses. Until recently and in accordance with Rabbinic law (and yes, even in the Family Court system), it was customary for the father to be solely responsible for the financial support of the children even if the mother is earning more.
On July 19, 2017, the Supreme court issued a ruling that set a new procedure for establishing child support obligations.
According to this new procedure, support payments in the cases of joint custody are to be calculated, based on the incomes of each of the ex-spouses, taking into account their individual dwelling expenses and how much “free” income remains. If the amounts for each of the spouses are similar or identical and the custody time is divided equally between them, there is a good chance that no support payments at all will be transferred between the ex-spouses.
It goes without saying that there are always variables and particulars and that there are fathers who attempt to nullify their support obligations, without realizing that this is predicated on equally shared custody and childcare.
It is likewise understood that the Rabbinic Courts, who generally operate by the Jewish Law which exclusively obligates a father for child support, are having a difficult time processing and accepting this change. (This is a topic of its own and I will address it in a separate article in the future)
So the moral of the story is: be careful what you ask for and think it through. Thankfully, women are catching up to men (even though there is still a ways to go) in salaries and employment opportunities. And thankfully, men are taking a much greater role in bringing up their children. Unfortunately for many women (i.e. those whose earnings are at the lower end of the salary ranges), the social changes that increased the involvement of fathers in rearing their children, has also created changes in the legal system – and not always in the ways that these women had anticipated.
What do you think? | <urn:uuid:89b77ed7-be65-49ec-b405-a20a22581117> | CC-MAIN-2023-40 | https://jayhaitlaw.com/does-equality-for-women-reduce-the-obligations-of-husbands/ | 2023-09-26T05:26:27Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.977392 | 1,084 |
In this time of economic uncertainty, what position should your company brand take in a time of crisis?
- Focus on Your Foundation Philosophy
Back to your roots. Your base customers have stuck with you through the hard times because of the ideology that you established back in the beginning. Recapitulate on those foundation principals, your core beliefs.
- Be Authentic
Projecting authenticity in your brand is essential during times of crisis. Bring in the compassion element and let your heart have bearing in your message. This is the time to bring in the human element of your brand. The human element should always be present in your brand, but now is the time to let it shine.
- Adapt to the Change
Post crisis we will need to navigate from a global perspective to a local perspective; creating a stronger sense of community through a domestic presence. We will not be returning to the traditional ways of business. Some of the products that you have in your repertoire are going to have to go to the wayside. Do not fret. Use this as an opportunity for innovation. A repositioning is essential here. What niche that is not being met can be filled by your product offerings? That new product you have been holding back on, this could be the perfect time to reveal your reshaping with new methods, new devices.
We are all ready for the new. Don’t feel like you have to “stay in your lane.” This is a time to revitalize and refresh for success. | <urn:uuid:c4f8d382-3fc5-4d30-b382-4ef5b968693a> | CC-MAIN-2023-40 | https://jcrossdesign.com/riding-the-wave/ | 2023-09-26T06:36:01Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.9477 | 306 |
Atherosclerotic Plaque as Infected Biofilm on Electron Microscopy
by Jeffrey Dach MD
Highlights of the Matters from the Heart ICIM March 2019 Philadelphia Meeting.
At the recent Integrative Medicine Meeting, Dr Thomas Levy gave a great talk on dental issues seeding infection in atherosclerotic plaque. He urged all practitioners to do 3-D dental xrays to find dental infection in patients with coronary artery disease. Indeed, modern imaging with scanning electron microscopy of vascular wall biopsies shows the typical rod shaped and spherical shaped micro-organisms entangled in a mesh like network compatible with infected biofilm. (see RED ARROW left image) More of this topic is available from Dr Levy’s 2017 book: Hidden Epidemic.
Benefits of the Plant Based Diet
Another speaker at the meeting, Dr Joel Kahn also spoke about the plant based diet. He also discussed metabolic endotoxemia, ie.”leaky gut” as another source of origin for seeding infection into the atherosclerotic plaque, thus causing heart disease. Both Joel Kahn and Kirk Hamilton mentioned the 2017 article by Esselstyn.(40) who conducted a Plant Based Diet study of almost 200 patients with significant coronary artery disease. Dr Esselstyn says:
“During four years of follow up, 99.4% of the participants who adhered to WFPBN (plant based diet) avoided any major cardiac event including heart attack, stroke, and death, and angina improved or resolved in 93%. Of the 21 non-adherent participants, 13 (62%) experienced an adverse event.”(40)
Kirk Hamilton and Steven Frye, both attending the meeting, speculate that efficacy of the plant based diet may be due to antimicrobial properties of plant roots such as Garlic. Dr Stephen Fry’s lab has identified soil fungi organisms in atherosclerotic plaque. Dr Frye mentions that plants root in the soil and are exposed to soil fungi, and over centuries, have developed resistance to soil fungi for their own survival. (Link to Kirk Hamilton podcast with Stephen Fry)
Biological Evidence Supporting Infection-Based Model of Atherogenesis.
Dr Kozorov in 2017 Cardiovascular Research describes two routes for invasion of bacteria into atherosclerotic plaques (red bugs in diagram below) .(9-10) One is by direct invasion across the endothelium or vasa vasorum, the other is indirectly, internalized in macrophages as a “Trojan Horses”. The bacteria (small red bugs) are carried into the atheroma inside invading macrophages.(see diagram below)
Above diagram: Red bugs are the invading bacteria. courtesy of : Kozarov, Emil et al.. “View of statins as antimicrobials in cardiovascular risk modification.” Card Res 102.3 (2014): 362-374. Fig 2. Dr Kozorov says:(10)
“Biological evidence supporting infection-based model of atherogenesis. Both bacteraemia and phagocyte-mediated delivery of bacteria to the site of inflammation are indicated. Bacteraemic organisms are invading the endothelial layer and spreading into vessel wall (left), releasing pro-inflammatory chemokines (such as MCP-1). Blood monocytes (MN) and macrophages (MΦ) are thus activated, prompting their adhesion and diapedesis. MN, monocyte; MΦ, macrophage with internalized bacteria; EC, endothelial cell; SMC, smooth muscle cell; MCP-1, monocyte chemotactic protein-1; Apoptotic EC, apoptotic endothelial cell releasing intracellular bacteria.” (10)
Dr. Kozorov makes the point that statin drugs are also anti-microbial, and their efficacy is probably due to anti-microbial and anti-inflammatory effects, not due to cholesterol lowering.(9-10)
Scanning Electron Microscopy of Atherosclerotic Plaques Specimens
Above Image Courtesy of : Armingohar, Zahra, et al. “Bacteria and bacterial DNA in atherosclerotic plaque and aneurysmal wall biopsies from patients with and without periodontitis.” Journal of oral microbiology 6.1 (2014): 23408. (1) Fig. 1 Scanning electron micrographs of bacteria in vascular biopsies from patients with periodontitis. (a) Area of aneurysmal wall with bacteria entangled in meshwork of delicate fibers. Apparently, division of coccus-shaped bacteria is occurring.
Dr Armingohar in the 2014 Journal of Microbiology studied atherosclerotic plaque and aneurysm wall biopsies in patients with and without periodontitis.(1) Using scanning electron microscopy, Dr Armingohar found a rod shaped and spherical shaped forms entangled in a mesh like network compatible with infected biofilm. (see above image) Some of the microbial life-forms were actively budding.
FISH 16s and 23s Ribosome DNA found in Atheromas
Dr Bernard Lanter’s lab uses fluorescent staining for 16s and 23s ribosome DNA to identify bacterial signatures in atheromas obtained from carotid artery surgical specimens (2) (See diagram below) Note two different strains of bacteria (green stain for 16s and red stain for 23s) are located withing the same distribution within the atheroma material. Dr Lanter found bacterial signatures in diseased tissue, and not in healthy tissue.
Above image courtesy of Bernard Lanter (2): Lanter, B. B., and D. G. Davies. “Propionibacterium acnes Recovered from Atherosclerotic Human Carotid Arteries Undergoes Biofilm Dispersion and Releases Lipolytic and Proteolytic Enzymes in Response to Norepinephrine Challenge In Vitro.” Infection and immunity 83.10 (2015): 3960-3971.(2)
Green fluorescence indicates the presence of the bound eubacterial 16S rRNA gene probe, while red fluorescence indicates the presence of the bound P. acnes 23S rRNA gene probe. Healthy tissue contains no bound probe, while diseased tissue contains bound eubacterial 16S rRNA and P. acnes 23S rRNA gene probes.
Conclusion: The original pathiologists more than 100 years ago considered atherosclerosis to be an infection. After all these years, modern imaging techniques are proving they were right all along.
Articles with Related Interest:
Jeffrey Dach MD
7450 Griffin Road Suite 180.190
Davie, Fl 33314
This article is Part Two, for part one click here.
Links and References:
1) Armingohar, Zahra, et al. “Bacteria and bacterial DNA in atherosclerotic plaque and aneurysmal wall biopsies from patients with and without periodontitis.” Journal of oral microbiology 6.1 (2014): 23408.
2) Lanter, B. B., and D. G. Davies. “Propionibacterium acnes Recovered from Atherosclerotic Human Carotid Arteries Undergoes Biofilm Dispersion and Releases Lipolytic and Proteolytic Enzymes in Response to Norepinephrine Challenge In Vitro.” Infection and immunity 83.10 (2015): 3960-3971.
Green fluorescence indicates the presence of the bound eubacterial 16S rRNA gene probe, while red fluorescence indicates the presence of the bound P. acnes 23S rRNA gene probe. Healthy tissue contains no bound probe, while diseased tissue contains bound eubacterial 16S rRNA and P. acnes 23S rRNA gene probes.
3) Lanter, Bernard B., Karin Sauer, and David G. Davies. “Bacteria present in carotid arterial plaques are found as biofilm deposits which may contribute to enhanced risk of plaque rupture.” MBio 5.3 (2014): e01206-14.
4) Schor J and Alschuler L. Bacterial Growth in Arteries Implicated in Heart Attacks Stress, biofilms, and cardiovascular disease . Natural Medicine Journal August 2014 Vol. 6 Issue 8.
5) Ott SJ, et al. Fungal rDNA signatures in coronary atherosclerotic plaques. Environ Microbiol. 2007;9(12):3035-45.
6) Ott, Stephan J., et al. “Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease.” Circulation 113.7 (2006): 929-937.Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease.
Bacterial infection has been discussed as a potential etiologic factor in the pathophysiology of coronary heart disease (CHD). This study analyzes molecular phylogenies to systematically explore the presence, frequency, and diversity of bacteria in atherosclerotic lesions in patients with CHD.
METHODS AND RESULTS: We investigated 16S rDNA signatures in atherosclerotic tissue obtained through catheter-based atherectomy of 38 patients with CHD, control material from postmortem patients (n=15), and heart-beating organ donors (n=11) using clone libraries, denaturating gradient gel analysis, and fluorescence in situ hybridization. Bacterial DNA was found in all CHD patients by conserved PCR but not in control material or in any of the normal/unaffected coronary arteries. Presence of bacteria in atherosclerotic lesions was confirmed by fluorescence in situ hybridization. A high overall bacterial diversity of >50 different species, among them Staphylococcus species, Proteus vulgaris, Klebsiella pneumoniae, and Streptococcus species, was demonstrated in >1500 clones from a combined library and confirmed by denaturating gradient gel analysis. Mean bacterial diversity in atheromas was high, with a score of 12.33+/-3.81 (range, 5 to 22). A specific PCR detected Chlamydia species in 51.5% of CHD patients.
CONCLUSIONS: Detection of a broad variety of molecular signatures in all CHD specimens suggests that diverse bacterial colonization may be more important than a single pathogen. Our observation does not allow us to conclude that bacteria are the causative agent in the etiopathogenesis of CHD. However, bacterial agents could have secondarily colonized atheromatous lesions and could act as an additional factor accelerating disease progression.
7) Fry SE, et al Putative biofilm-forming organisms in the human vasculature: expanded case reports and review of the literature. Phlebological Review 2014; 22(1): 24–37.Biofilm_forming organisms human vasculature Stephen Eugene Fry Phlebological Review 2014
8) Ellis, Jeremy E., et al. “Evidence for polymicrobial communities in explanted vascular filters and atheroma debris.” Molecular and cellular probes 33 (2017): 65-77.
Microbial communities have been implicated in a variety of disease processes and have been intermittently observed in arterial disease; however, no comprehensive unbiased community analysis has been performed. We hypothesize that complex microbial communities may be involved in chronic vascular diseases as well and may be effectively characterized by molecular assays.
OBJECTIVE: The main objective is to survey vascular debris, atheroma, and vascular filters for polymicrobial communities consisting of prokaryotic and eukaryotic microbes, specifically eukaryotic microbes.
METHODS AND RESULTS: We examined vascular aspirates of atheromatous debris or embolic protection filters in addition to matched peripheral blood samples, from fifteen patients, as well as three cadaveric coronary arteries from two separate patients, for microbial communities. General fluorescence microscopy by Höechst and ethidium bromide DNA stains, prokaryotic and eukaryotic community analysis by Next Generation DNA Sequencing (NGS), and a eukaryotic microbial 9 probe multiplexed quantitative PCR were used to detect and characterize the presence of putative polymicrobial communities. No prokaryotes were detected in peripheral blood; however, in 4 of 9 sequenced filters and in 2 of 7 sequenced atheroma debris samples, prokaryotic populations were identified. By DNA sequencing, eukaryotic microbes were detected in 4 of 15 blood samples, 5 of the 9 sequenced filters, and 3 of the 7 atheroma debris samples. The quantitative multiplex PCR detected sequences consistent with eukaryotic microbes in all 9 analyzed filter samples as well as 5 of the 7 atheroma debris samples. Microscopy reveals putative polymicrobial communities within filters and atheroma debris. The main contributing prokaryotic species in atheroma debris suggest a diverse and novel composition. Additionally, Funneliformis mosseae, an arbuscular mycorrhizal fungus in the Glomeraceae family, was detected in the coronary hard plaque from two patients. Well studied biofilm forming bacteria were not detectable in circulating peripheral blood and were not universally present in atheroma or filters. Analyses of the sequenced eukaryotes are consistent with a diverse of array poorly studied environmental eukaryotes. In summary, out of 15 patients, 6 exhibited molecular evidence of prokaryotes and 14 had molecular evidence of eukaryotic and/or polymicrobial communities in vivo, while 2 post-mortem coronary plaque samples displayed evidence of fungi.
CONCLUSION: Prokaryotes are not consistently observed in atheroma debris or filter samples; however, detection of protozoa and fungi in these samples suggests that they may play a role in arterial vascular disease or atheroma formation.
9) Kozarov, Emil. “Bacterial invasion of vascular cell types: vascular infectology and atherogenesis.” Future cardiology 8.1 (2012): 123-138.
Cultivation of microorganisms from diseased tissue has been demonstrated,
Biological evidence supporting infection-based model of atherogenesis. Both bacteraemia and phagocyte-mediated delivery of bacteria to the site of inflammation are indicated. Bacteraemic organisms are invading the endothelial layer and spreading into vessel wall (left), releasing pro-inflammatory chemokines (such as MCP-1). Blood monocytes (MN) and macrophages (MΦ) are thus activated, prompting their adhesion and diapedesis. Transmigrating leucocytes (centre) can carry internalized bacteria, thus promoting systemic dissemination of bacteria. In addition, the internalization of bacteria can switch them into uncultivable state (black into grey), while their internalization by phagocytes can reactivate them back to metabolic activity (from grey to black). The growth of atheromas is due in large extent to macrophage-secreted growth factors that induce SMC proliferation. Host cell death (depicted at right) can also lead to pathogen release in the tissue. MN, monocyte; MΦ, macrophage with internalized bacteria; EC, endothelial cell; SMC, smooth muscle cell; MCP-1, monocyte chemotactic protein-1; Apoptotic EC, apoptotic endothelial cell releasing intracellular bacteria.
10) Kozarov, Emil, Teresa Padro, and Lina Badimon. “View of statins as antimicrobials in cardiovascular risk modification.” Cardiovascular research 102.3 (2014): 362-374.
11) Mawhorter SD, Lauer MA. Is atherosclerosis an infectious disease? Cleve Clin J Med. 2001;68(5):449-58.
12) Kuo CC, Shor A, Campbell LA, et al. Demonstration of Chlamydia pneumoniae in atherosclerotic lesions of coronary arteries. J Infect Dis. 1993;167(4):841-9.
13) Koren O, at al. Human oral, gut, and plaque microbiota in patients with atherosclerosis. Proc Natl Acad Sci U S A. 2011;108 Suppl 1:4592-8.
14) Chakravorty, S et al. “Detailed analysis of 16S ribosomal RNA gene segments for diagnosis of pathogenic bacteria.” Journal of microbiological methods 69.2 (2007): 330-339.
15) Brown, J. Mark, and Stanley L. Hazen. “The Gut Microbial Endocrine Organ: Bacterially-Derived Signals Driving Cardiometabolic Diseases.” Annual review of medicine 66 (2015): 343.
“metabolic endotoxemia” because it has been found to be prevalent in many chronic metabolic diseases such as obesity, type II diabetes, and atherosclerosis
LPS in Atheromatoud Plaque
16) Carnevale, Roberto, et al. “Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque.” Scientific reports 8.1 (2018): 3598.
17) Lehr, Hans-Anton, et al. “Immunopathogenesis of atherosclerosis Endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet.” Circulation 104.8 (2001): 914-920.
LPS challenged Mouse Model
18) Cuaz-Pérolin, Clarisse, et al. “Antiinflammatory and antiatherogenic effects of the NF-κB inhibitor acetyl-11-keto-β-boswellic acid in LPS-challenged ApoE−/− mice.” Arteriosclerosis, thrombosis, and vascular biology 28.2 (2008): 272-277.
Periodontal Disease in Pathogenesis of Atherosclerosis
19) Vojdani, A. “The Role of Periodontal Disease and Other Infections in the Pathogenesis of Atherosclerosis and Systemic Diseases.” Townsend Letter for Doctors and Patients (2000): 52–57.
20) Chhibber-Goel, Jyoti, et al. “Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients.” NPJ biofilms and microbiomes 2.1 (2016): 7.
21) Liljestrand, John M., et al. “Lipopolysaccharide mediator between periodontitis and coronary artery disease Liljestrand J clin periodontology 2017.” Journal of clinical periodontology 44.8 (2017): 784-792.
Transmission electron microscopy identified bacteria in all 9 thombus samples.
22) Pessi, Tanja, et al. “Bacterial signatures in thrombus aspirates of patients with myocardial infarction.” Circulation 127.11 (2013): 1219-1228.
Infectious agents, especially bacteria and their components originating from the oral cavity or respiratory tract, have been suggested to contribute to inflammation in the coronary plaque, leading to rupture and the subsequent development of coronary thrombus. We aimed to measure bacterial DNA in thrombus aspirates of patients with ST-segment-elevation myocardial infarction and to check for a possible association between bacteria findings and oral pathology in the same cohort.
METHODS AND RESULTS:Thrombus aspirates and arterial blood from patients with ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention (n=101; 76% male; mean age, 63.3 years) were analyzed with real-time quantitative polymerase chain reaction with specific primers and probes to detect bacterial DNA from several oral species and Chlamydia pneumoniae. The median value for the total amount of bacterial DNA in thrombi was 16 times higher than that found in their blood samples. Bacterial DNA typical for endodontic infection, mainly oral viridans streptococci, was measured in 78.2% of thrombi, and periodontal pathogens were measured in 34.7%. Bacteria-like structures were detected by transmission electron microscopy in all 9 thrombus samples analyzed; whole bacteria were detected in 3 of 9 cases. Monocyte/macrophage markers for bacteria recognition (CD14) and inflammation (CD68) were detected in thrombi (8 of 8) by immunohistochemistry. Among the subgroup of 30 patients with myocardial infarction examined by panoramic tomography, a significant association between the presence of periapical abscesses and oral viridans streptococci DNA-positive thrombi was found (odds ratio, 13.2; 95% confidence interval, 2.11-82.5; P=0.004).
Dental infection and oral bacteria, especially viridans streptococci, may be associated with the development of acute coronary thrombosis.
23) J Periodontol. 2005 Nov;76(11 Suppl):2085-8.
Dental infections and cardiovascular diseases: a review.
Mattila KJ1, Pussinen PJ, Paju S.
Accumulating evidence suggests that chronic infections, such as periodontitis, are associated with increased risk for cardiovascular diseases (CVD). The mechanisms behind the association are not known. Like herpes viruses and Chlamydia pneumoniae, periodontal pathogens cause atherosclerosis in experimental animals and have been found in human atherosclerotic lesions. Higher concentrations of total and low density lipoprotein (LDL) cholesterol and triglycerides and lower concentrations of high density lipoprotein (HDL) cholesterol have been observed in individuals with periodontitis before periodontal treatment. Periodontitis also induces a peripheral inflammatory and immune response, reflected in elevated concentrations of C-reactive protein (CRP) and IgA-class antibodies to periodontal pathogens. The prevalence of CVD seems to be highest in those individuals in whom periodontitis coexists with elevated CRP levels. This may indicate that periodontitis is a CVD risk factor in individuals who react to the infection with a systemic inflammatory and immune response. This may be due to genetic reasons and may also apply to other chronic low-grade infections.
24) Indian J Dent Res. 2010 Apr-Jun;21(2):248-52. 16S rRNA-based detection of oral pathogens in coronary atherosclerotic plaque.
Mahendra J1, Mahendra L, Kurian VM, Jaishankar K, Mythilli R.
Atherosclerosis develops as a response of the vessel wall to injury. Chronic bacterial infections have been associated with an increased risk for atherosclerosis and coronary artery disease. The ability of oral pathogens to colonize in coronary atheromatous plaque is well known.
The aim of this study was to detect the presence of Treponema denticola, Porphyromonas gingivalis and Campylobacter rectus in the subgingival and atherosclerotic plaques of patients with coronary artery disease.
MATERIALS AND METHODS:
Fifty-one patients in the age group of 40-80 years with coronary artery disease were selected for the study. DNA was extracted from the plaque samples. The specific primers for T. denticola, C. rectus and P. gingivalis were used to amplify a part of the 16S rRNA gene by polymerase chain reaction.
STATISTICAL ANALYSIS USED:
Chi-square analysis, correlation coefficient and prevalence percentage of the microorganisms were carried out for the analysis.
Of the 51 patients, T. denticola, C. rectus and P. gingivalis were detected in 49.01%, 21.51% and 45.10% of the atherosclerotic plaque samples.
Our study revealed the presence of bacterial DNA of the oral pathogenic microorganisms in coronary atherosclerotic plaques. The presence of the bacterial DNA in the coronary atherosclerotic plaques in significant proportion may suggest the possible relationship between periodontal bacterial infection and genesis of coronary atherosclerosis.
25) J Periodontol. 2000 Oct;71(10):1554-60.
Identification of periodontal pathogens in atheromatous plaques.
Haraszthy VI1, Zambon JJ, Trevisan M, Zeid M, Genco RJ.
Recent studies suggest that chronic infections including those associated with periodontitis increase the risk for coronary vascular disease (CVD) and stroke. We hypothesize that oral microorganisms including periodontal bacterial pathogens enter the blood stream during transient bacteremias where they may play a role in the development and progression of atherosclerosis leading to CVD.
METHODS: To test this hypothesis, 50 human specimens obtained during carotid endarterectomy were examined for the presence of Chlamydia pneumoniae, human cytomegalovirus, and bacterial 16S ribosomal RNA using specific oligonucleotide primers in polymerase chain reaction (PCR) assays. Approximately 100 ng of chromosomal DNA was extracted from each specimen and then amplified using standard conditions (30 cycles of 30 seconds at 95 degrees C, 30 seconds at 55 degrees C, and 30 seconds at 72 degrees C). Bacterial 16S rDNA was amplified using 2 synthetic oligonucleotide primers specific for eubacteria. The PCR product generated with the eubacterial primers was transferred to a charged nylon membrane and probed with digoxigenin-labeled synthetic oligonucleotides specific for Actinobacillus actinomycetemcomitans, Bacteroides forsythus, Porphyromonas gingivalis, and Prevotella intermedia.
RESULTS: Eighty percent of the 50 endarterectomy specimens were positive in 1 or more of the PCR assays. Thirty-eight percent were positive for HCMV and 18% percent were positive for C. pneumoniae. PCR assays for bacterial 16S rDNA also indicated the presence of bacteria in 72% of the surgical specimens. Subsequent hybridization of the bacterial 16S rDNA positive specimens with species-specific oligonucleotide probes revealed that 44% of the 50 atheromas were positive for at least one of the target periodontal pathogens. Thirty percent of the surgical specimens were positive for B. forsythus, 26% were positive for P. gingivalis, 18% were positive for A. actinomycetemcomitans, and 14% were positive for P. intermedia. In the surgical specimens positive for periodontal pathogens, more than 1 species was most often detected. Thirteen (59%) of the 22 periodontal pathogen-positive surgical specimens were positive for 2 or more of the target species.
CONCLUSIONS: Periodontal pathogens are present in atherosclerotic plaques where, like other infectious microorganisms such as C. pneumoniae, they may play a role in the development and progression of atherosclerosis leading to coronary vascular disease and other clinical sequelae.
Infection Found in Cerebral Aneurysms
26) J Neurol Neurosurg Psychiatry. 2013 Nov;84(11):1214-8.
The connection between ruptured cerebral aneurysms and odontogenic bacteria. Pyysalo MJ1, Pyysalo LM, Pessi T, Karhunen PJ, Öhman JE.
Patients with ruptured saccular intracranial aneurysms have excess long-term mortality due to cerebrovascular and cardiovascular diseases compared with general population. Chronic inflammation is detected in ruptured intracranial aneurysms, abdominal aortic aneurysms and coronary artery plaques. Bacterial infections have been suggested to have a role in the aetiology of atherosclerosis. Bacteria have been detected both in abdominal and coronary arteries but their presence in intracranial aneurysms has not yet been properly studied.
OBJECTIVE: The aim of this preliminary study was to assess the presence of oral and pharyngeal bacterial genome in ruptured intracranial aneurysms and to ascertain if dental infection is a previously unknown risk factor for subarachnoid haemorrhage.
METHODS: A total of 36 ruptured aneurysm specimens were obtained perioperatively in aneurysm clipping operations (n=29) and by autopsy (n=7). Aneurysmal sac tissue was analysed by real time quantitative PCR with specific primers and probes to detect bacterial DNA from several oral species. Immunohistochemical staining for bacterial receptors (CD14 and toll-like receptor-2 (TLR-2)) was performed from four autopsy cases.
RESULTS: Bacterial DNA was detected in 21/36 (58%) of specimens. A third of the positive samples contained DNA from both endodontic and periodontal bacteria. DNA from endodontic bacteria were detected in 20/36 (56%) and from periodontal bacteria in 17/36 (47%) of samples. Bacterial DNA of the Streptococcus mitis group was found to be most common. Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum and Treponema denticola were the three most common periodontal pathogens. The highly intensive staining of CD14 and TLR-2 in ruptured aneurysms was observed.
CONCLUSIONS: This is the first report showing evidence that dental infection could be a part of pathophysiology in intracranial aneurysm disease.
27) Acta Odontol Scand. 2016;74(4):315-20. Bacterial DNA findings in ruptured and unruptured intracranial aneurysms.
Pyysalo MJ1,2, Pyysalo LM3, Pessi T4, Karhunen PJ4,5, Lehtimäki T6, Oksala N6,7, Öhman JE3.
Chronic inflammation has earlier been detected in ruptured intracranial aneurysms. A previous study detected both dental bacterial DNA and bacterial-driven inflammation in ruptured intracranial aneurysm walls. The aim of this study was to compare the presence of oral and pharyngeal bacterial DNA in ruptured and unruptured intracranial aneurysms. The hypothesis was that oral bacterial DNA findings would be more common and the amount of bacterial DNA would be higher in ruptured aneurysm walls than in unruptured aneurysm walls.
MATERIALS AND METHODS: A total of 70 ruptured (n = 42) and unruptured (n = 28) intracranial aneurysm specimens were obtained perioperatively in aneurysm clipping operations. Aneurysmal sac tissue was analysed using a real-time quantitative polymerase chain reaction to detect bacterial DNA from several oral species. Both histologically non-atherosclerotic healthy vessel wall obtained from cardiac by-pass operations (LITA) and arterial blood samples obtained from each aneurysm patient were used as control samples.
RESULTS: Bacterial DNA was detected in 49/70 (70%) of the specimens. A total of 29/42 (69%) of the ruptured and 20/28 (71%) of the unruptured aneurysm samples contained bacterial DNA of oral origin. Both ruptured and unruptured aneurysm tissue samples contained significantly more bacterial DNA than the LITA control samples (p-values 0.003 and 0.001, respectively). There was no significant difference in the amount of bacterial DNA between the ruptured and unruptured samples.
CONCLUSION: Dental bacterial DNA can be found using a quantitative polymerase chain reaction in both ruptured and unruptured aneurysm walls, suggesting that bacterial DNA plays a role in the pathogenesis of cerebral aneurysms in general, rather than only in ruptured aneurysms.
28) Louhelainen, Anne-Mari, et al. “Oral bacterial DNA findings in pericardial fluid.” Journal of oral microbiology 6.1 (2014): 25835.
We recently reported that large amounts of oral bacterial DNA can be found in thrombus aspirates of myocardial infarction patients. Some case reports describe bacterial findings in pericardial fluid, mostly done with conventional culturing and a few with PCR; in purulent pericarditis, nevertheless, bacterial PCR has not been used as a diagnostic method before.
OBJECTIVE: To find out whether bacterial DNA can be measured in the pericardial fluid and if it correlates with pathologic-anatomic findings linked to cardiovascular diseases.
METHODS: Twenty-two pericardial aspirates were collected aseptically prior to forensic autopsy at Tampere University Hospital during 2009-2010. Of the autopsies, 10 (45.5%) were free of coronary artery disease (CAD), 7 (31.8%) had mild and 5 (22.7%) had severe CAD. Bacterial DNA amounts were determined using real-time quantitative PCR with specific primers and probes for all bacterial strains associated with endodontic disease (Streptococcus mitis group, Streptococcus anginosus group, Staphylococcus aureus/Staphylococcus epidermidis, Prevotella intermedia, Parvimonas micra) and periodontal disease (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, Fusobacterium nucleatus, and Dialister pneumosintes).
RESULTS: Of 22 cases, 14 (63.6%) were positive for endodontic and 8 (36.4%) for periodontal-disease-associated bacteria. Only one case was positive for bacterial culturing. There was a statistically significant association between the relative amount of bacterial DNA in the pericardial fluid and the severity of CAD (p=0.035).
CONCLUSIONS: Oral bacterial DNA was detectable in pericardial fluid and an association between the severity of CAD and the total amount of bacterial DNA in pericardial fluid was found, suggesting that this kind of measurement might be useful for clinical purposes.
bacteria colonize Aortic Aneurysms
A wide variety of bacteria, including oral bacteria, was found to colonize aortic aneurysms and may play a role in their development.
29) da Silva, Rafael Marques, et al. “Bacterial diversity in aortic aneurysms determined by 16S ribosomal RNA gene analysis.” Journal of vascular surgery 44.5 (2006): 1055-1060.
A wide variety of bacteria, including oral bacteria, was found to colonize aortic aneurysms and may play a role in their development.
Aortic aneurysms are common vascular conditions that cause considerable morbidity and mortality. Understanding of the mechanisms involved in the pathogenesis of the condition remains limited. Recently, infection has been suggested as possible contributor in the development of the disease. The aim of the present study was to examine aortic aneurysms for the presence of bacterial DNA using polymerase chain reaction (PCR) targeting the 16S ribosomal RNA (rRNA) gene, followed by cloning and sequencing.
METHODS:Universal eubacterial primers were used to amplify 16S rRNA bacterial genes in 10 specimens from arterial walls of aortic aneurysms. Subsequently, PCR amplicons were cloned into Escherichia coli and sequencing of the cloned inserts was used to determine species identity or closest relatives by comparison with known sequences in GenBank.
RESULTS:Sequences of Stenotrophomonas spp., including S. maltophilia (formerly Pseudomonas homology group V) were detected in six aneurysm samples. Propionibacterium acnes was identified in five samples, and Brevundimonas diminuta (formerly P. diminuta) in four samples. Other species previously assigned to the Pseudomonas genus such as Comamonas testosteroni, Delftia acidovorans, Burkholderia cepacia, Herbaspirillum sp., and Acidovorax sp. were also detected. Some clones fell into other environmental species, including Methylobacterium sp. and Bradyrhizobium elkanii, and others represented bacteria that have not yet been cultivated. DNA sequences from oral bacteria, including Streptococcus sanguinis, Tannerella forsythia, and Leptotrichia buccalis were detected. Sequences from Prevotella melaninogenica and Lactobacillus delbrueckii, which are commonly found in both mouth and gastrointestinal tract, were also detected. Additional species included Dermacoccus spp. and Corynebacterium vitaeruminis.
CONCLUSIONS:A wide variety of bacteria, including oral bacteria, was found to colonize aortic aneurysms and may play a role in their development. Several of these microorganisms have not yet been cultivated.
CLINICAL RELEVANCE:Although Chlamydophila pneumoniae has been detected in aneurysmal walls, its exact role in the condition remains inconclusive. Overall, there is scarce information about the role of microorganisms in aneurysmal disease. In the present study, we used molecular genetics to detect a diversity of bacteria in arterial walls of aortic aneurysms. The presence of multiple microorganisms in aneurysmal disease may have implications for chemoprophylaxis and antibiotic treatment if directed only at C.pneumoniae.
30) Renko, Jaana, et al. “Bacterial signatures in atherosclerotic lesions represent human commensals and pathogens.” Atherosclerosis 201.1 (2008): 192-197.we defined bacterial DNA signatures in surgically removed sterile abdominal aorta samples of patients with aortic atherosclerosis.
Renko, Jaana, et al. “Bacterial DNA signatures in carotid atherosclerosis represent both commensals and pathogens of skin origin.” European Journal of Dermatology 23.1 (2013): 53-58.nearly all (94%) of the sequences were associated with the human skin microbiome.
31) Paraskevas, K. I., D. P. Mikhailidis, and A. D. Giannoukas.Periodontitis and abdominal aortic aneurysms: a random association or a pathogenetic link?International angiology: a journal of the International Union of Angiology 28.6 (2009): 431.
A number of micro-organisms have been implicated in the development/progression of abdominal aortic aneurysms (AAAs), thus suggesting an infective theory of AAA pathogenesis. Periodontitis may be involved in the development of AAAs by means of introduction of subgingival plaque periodontal bacteria into the bloodstream and degeneration of the aortic wall. A different theory supports that the findings of periodontal pathogens in AAA biopsies are a secondary phenomenon with transient bacteremia leading to invasion of already formed AAAs. It is not yet clear whether the periodontopathic bacteria accelerate the growth/weakening of the aortic wall or whether they are secondary colonizers of AAAs. Clarification of the association between periodontal disease and AAAs in large-scale studies holds implications for a role for chemoprophylaxis/antibiotic treatment in the management of AAAs.
Leaky Gut – Endotoxemia
32) Fukui, H. ” Endotoxin and Other Microbial Translocation Markers in the Blood: A Clue to Understand Leaky Gut Syndrome” Cell Mol Med 2 (2016): 3. Endotoxin and microbial translocation markers in blood leaky gut syndrome Fukui Cell Mol Med 2016
Biofilm in Atherosclerotic Plaques
33) Snow, D. E., et al. “The presence of biofilm structures in atherosclerotic plaques of arteries from legs amputated as a complication of diabetic foot ulcers.” Journal of wound care 25.Sup2 (2016): S16-S22.Bacterial Biofilm in atherosclerotic plaques of leg arteries amputated diabetic foot ulcers Snow J of wound care 2016
Atherosclerosis, rather than microcirculatory impairment caused by endothelial cell dysfunction, is the main driver of circulatory compromise in patients with diabetic limbs. The presence of atherosclerotic plaque at the trifurcation is a significant contributor to amputation of diabetic legs. The presence of bacteria and other microorganisms in atherosclerotic plaque has long been known, however, the cause of chronic inflammation and the role of bacteria/viruses in atherosclerosis have not been studied in detail. The objective of this study was to clarify the cause of the chronic inflammation within atherosclerotic plaques, and determine if any bacteria and/or viruses are involved in the inflammatory pathway.
METHOD:This study uses fluorescence microscopy and fluorescence in-situ hybridisation (FISH) to identify components of biofilm in atherosclerotic arteries. These tools are also used to identify individual bacteria, and determine the architectural spatial location within the atherosclerotic plaque where the bacteria can be found.
RESULTS:The results indicate that the presence of biofilms in grossly involved arteries may be an important factor in chronic inflammatory pathways of atherosclerotic progression, in the amputated limbs of patients with diabetic foot ulcers and vascular disease.
CONCLUSION:While the presence of bacterial biofilm structures in atherosclerotic plaque does not prove that biofilm is the proximate cause of atherosclerosis, it could contribute to the persistent inflammation associated with it. Second, the synergistic relationship between the atherosclerotic infection and the diabetic foot ulcer may ultimately contribute to higher amputation rates in diabetics.
Pseudomonas in coronary Thrombi
34) Hansen, Gorm Mørk, et al. “Pseudomonas aeruginosa Microcolonies in Coronary Thrombi from Patients with ST-Segment Elevation Myocardial Infarction.” PloS one 11.12 (2016): e0168771.
Chronic infection is associated with an increased risk of atherothrombotic disease and direct bacterial infection of arteries has been suggested to contribute to the development of unstable atherosclerotic plaques. In this study, we examined coronary thrombi obtained in vivo from patients with ST-segment elevation myocardial infarction (STEMI) for the presence of bacterial DNA and bacteria.
Aspirated coronary thrombi from 22 patients with STEMI were collected during primary percutaneous coronary intervention and arterial blood control samples were drawn from radial or femoral artery sheaths.
Analyses were performed using 16S polymerase chain reaction and with next-generation sequencing to determine bacterial taxonomic classification. In selected thrombi with the highest relative abundance of Pseudomonas aeruginosa DNA, peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) with universal and species specific probes was performed to visualize bacteria within thrombi. From the taxonomic analysis we identified a total of 55 different bacterial species.
DNA from Pseudomonas aeruginosa represented the only species that was significantly associated with either thrombi or blood and was >30 times more abundant in thrombi than in arterial blood (p<0.0001).
Whole and intact bacteria present as biofilm microcolonies were detected in selected thrombi using universal and P. aeruginosa-specific PNA-FISH probes. P. aeruginosa and vascular biofilm infection in culprit lesions may play a role in STEMI, but causal relationships remain to be determined.
Several samples show bacterial DNA far exceeding what would be expected by contamination, suggesting the bacteria may be propagating in the plaque.
35) Wolcott RD, Wolcott JJ, Palacio C, Rodriguez S (2012) A Possible Role of Bacterial Biofilm in the Pathogenesis of Atherosclerosis. J Bacteriol Parasitol 3:127. Bacterial Biofilm in Pathogenesis of Atherosclerosis Wolcott RD J Bact Parasit 2012
Multiple culture and molecular based studies have established the presence of bacteria in atherosclerotic plaques. Although bacteria are present within the plaque, there is no clear understanding or putative pathway as to what part bacteria might play, if any, in the pathogenesis of atherosclerosis. The current models for the pathogenesis of atherosclerotic plaque suggest that persistent infl ammation is an important factor; however, the possible sources for this sustained infl ammation are limited. The concept of biofilm infection, “a new paradigm of bacterial pathogenesis,” is introduced to show that bacteria, organized into a biofilm phenotype mode of growth, produces a sustained hyper-inflammatory host niche. Biofi lm produces an oxidative environment in a host infection. Samples of plaque from 10 patients were examined to compare 16S rDNA to 18S rDNA. Also 4 samples were evaluated in 2 separate locations to evaluate the homogeneity of bacteria within the sample. The 16S rDNA was also sequenced to identify the microorganisms present and their relative contribution to the sample. Several samples demonstrated large amounts of bacterial DNA. The spatial arrangement of bacterial DNA showed a very heterogeneous distribution of bacteria in the plaque. A heat map data analysis shows that for samples that were evaluated in 2 locations the bacteria identifi ed closely correlated. For all the samples combined, the predominant microbial species identifi ed have often been associated with the oral cavity. Several samples show bacterial DNA far exceeding what would be expected by contamination, suggesting the bacteria may be propagating in the plaque. If bacteria are propagating within the plaque, this would most likely be a biofi lm phenotype mode of growth. Biofi lm is known to produce a hyperinfl ammatory response in host environments, and therefore is a candidate for being the “engine” for the persistent infl ammation necessary for the pathogenesis of atherosclerosis.
Peri-Odontal Oral Infection
36) Chukkapalli, Sasanka S., et al. “Polymicrobial oral infection with four periodontal bacteria orchestrates a distinct inflammatory response and atherosclerosis in ApoEnull mice.” PLoS One 10.11 (2015): e0143291.
Periodontal disease (PD) develops from a synergy of complex subgingival oral microbiome, and is linked to systemic inflammatory atherosclerotic vascular disease (ASVD). To investigate how a polybacterial microbiome infection influences atherosclerotic plaque progression, we infected the oral cavity of ApoEnull mice with a polybacterial consortium of 4 well-characterized periodontal pathogens, Porphyromonas gingivalis, Treponema denticola, Tannerealla forsythia and Fusobacterium nucleatum, that have been identified in human atherosclerotic plaque by DNA screening. We assessed periodontal disease characteristics, hematogenous dissemination of bacteria, peripheral T cell response, serum inflammatory cytokines, atherosclerosis risk factors, atherosclerotic plaque development, and alteration of aortic gene expression. Polybacterial infections have established gingival colonization in ApoEnull hyperlipidemic mice and displayed invasive characteristics with hematogenous dissemination into cardiovascular tissues such as the heart and aorta. Polybacterial infection induced significantly higher levels of serum risk factors oxidized LDL (p < 0.05), nitric oxide (p < 0.01), altered lipid profiles (cholesterol, triglycerides, Chylomicrons, VLDL) (p < 0.05) as well as accelerated aortic plaque formation in ApoEnull mice (p < 0.05). Periodontal microbiome infection is associated with significant decreases in Apoa1, Apob, Birc3, Fga, FgB genes that are associated with atherosclerosis. Periodontal infection for 12 weeks had modified levels of inflammatory molecules, with decreased Fas ligand, IL-13, SDF-1 and increased chemokine RANTES. In contrast, 24 weeks of infection induced new changes in other inflammatory molecules with reduced KC, MCSF, enhancing GM-CSF, IFNγ, IL-1β, IL-13, IL-4, IL-13, lymphotactin, RANTES, and also an increase in select inflammatory molecules. This study demonstrates unique differences in the host immune response to a polybacterial periodontal infection with atherosclerotic lesion progression in a mouse model.
Mouse Model of periodontal bacteria spreading to atherosclerotic plaques
37) Chukkapalli, Sasanka S., et al. “Sequential colonization of periodontal pathogens in induction of periodontal disease and atherosclerosis in LDLRnull mice.” Pathogens and disease 75.1 (2017).
Periodontal disease (PD) and atherosclerotic vascular disease (ASVD) are both chronic inflammatory diseases with a polymicrobial etiology and have been epidemiologically associated. The purpose is to examine whether periodontal bacteria that infect the periodontium can also infect vascular tissues and enhance pre-existing early aortic atherosclerotic lesions in LDLRnull mice. Mice were orally infected with intermediate bacterial colonizer Fusobacterium nucleatum for the first 12 weeks followed by late bacterial colonizers (Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia) for the remaining 12 weeks mimicking the human oral microbiota ecological colonization. Genomic DNA from all four bacterial was detected in gingival plaque by PCR, consistently demonstrating infection of mouse gingival surfaces. Infected mice had significant levels of IgG and IgM antibodies, alveolar bone resorption, and showed apical migration of junctional epithelium revealing the induction of PD. These results support the ability of oral bacteria to cause PD in mice. Detection of bacterial genomic DNA in systemic organs indicates hematogenous dissemination from the gingival pockets.
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plaque is infected Biofilm
38) Jonsson, Annika Lindskog, et al. “Bacterial profile in human atherosclerotic plaques.” Atherosclerosis 263 (2017): 177-183.
We confirmed the presence of bacterial DNA in the atherosclerotic plaque by qPCR analysis of the 16S rRNA gene but observed no difference (n.s.) in the amount between either asymptomatic and symptomatic patients or different plaque regions A, B and C. Unweighted UniFrac distance metric analysis revealed no distinct clustering of samples by patient group or plaque region. Operational taxonomic units (OTUs) from 5 different phyla were identified, with the majority of the OTUs belonging to Proteobacteria (48.3%) and Actinobacteria (40.2%). There was no difference between asymptomatic and symptomatic patients, or plaque regions, when analyzing the origin of DNA at phylum, family or OTU level (n.s.).
Conclusions There were no major differences in bacterial DNA amount or microbial composition between plaques from asymptomatic and symptomatic patients or between different plaque regions, suggesting that other factors are more important in determining plaque vulnerability.
intestinal bacteria in plaques may original from the intestine.
39) Li, Chuanwei, et al. “Zonulin regulates intestinal permeability and facilitates enteric bacteria permeation in coronary artery disease.” Scientific reports 6 (2016): 29142.
The detection of intestinal bacterial by 16S rRNA gene amplification in both the blood sample and atherosclerotic plaques supports the notion that intestinal bacteria in plaques may original from the intestine.
Given the fact that zonulin is significantly elevated in atherosclerosis and increase intestinal IP, it’s possible that targeting zonulin using monoclonal antibody or inhibitors maybe a provocatively new way to move forward in CAD preventi and treatment.
Plant Based Diet Prevents MI
40) Esselstyn, Caldwell B. “A plant-based diet and coronary artery disease: a mandate for effective therapy.” Journal of geriatric cardiology: JGC 14.5 (2017): 317.
In 2014, we conducted a second larger study of 198 patients with significant CAD. Of these patients, 119 had undergone a prior coronary intervention with stents or bypass surgery, and 44 had a previous heart attack. There were multiple comorbidities including hypercholesterolemia, hypertension, obesity, and diabetes. During four years of follow up, 99.4% of the participants who adhered to WFPBN avoided any major cardiac event including heart attack, stroke, and death, and angina improved or resolved in 93%. Of the 21 non-adherent participants, 13 (62%) experienced an adverse event. When comparing these results to the well-known COURAGE, and Lyon Diet Heart Study, which consisted of conventionally treated participants, there is beyond a 30-fold difference in major cardiovascular events favoring WFPBN.
41) Curran, Samuel A., et al. “Bacteria in the adventitia of cardiovascular disease patients with and without rheumatoid arthritis.” PloS one 9.5 (2014): e98627.
The incidence of atherosclerosis is significantly increased in rheumatoid arthritis (RA). Infection is one factor that may be involved in the pathogenesis of both diseases. The cause of RA and atherosclerosis is unknown, and infection is one of the factors that may be involved in the pathogenesis of both diseases. The aims of this study were to identify bacteria in the aortic adventitia of patients with cardiovascular disease (CVD) in the presence and absence of RA, and to determine the effect of identified candidate pathogens on Toll-like receptor (TLR)-dependent signalling and the proinflammatory response. The aortic adventitia of 11 CVD patients with RA (RA+CVD) and 11 CVD patients without RA (CVD) were collected during coronary artery bypass graft surgery. Bacteria were detected in four samples from CVD patients and three samples from RA+CVD patients and identified by 16S rRNA gene sequencing. Methylobacterium oryzae was identified in all three RA+CVD samples, representing 44.1% of the bacterial flora. The effect of M. oryzae on TLR-dependent signalling was determined by transfection of HEK-293 cells. Although mild TLR2 signalling was observed, TLR4 was insensitive to M. oryzae. Human primary macrophages were infected with M. oryzae, and a TLDA qPCR array targeting 90 genes involved in inflammation and immune regulation was used to profile the transcriptional response. A significant proinflammatory response was observed, with many of the up-regulated genes encoding proinflammatory cytokines (IL-1α, IL-1β, IL-6, TNF-α) and chemokines (CCR7, IL-8). The aortic adventitia of CVD patients contains a wide range of bacterial species, and the bacterial flora is significantly less diverse in RA+CVD than CVD patients. M. oryzae may stimulate an proinflammatory response that may aggravate and perpetuate the pathological processes underlying atherosclerosis in RA patients.
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Serving Areas of: Hollywood, Aventura, Miami, Fort Lauderdale, Pembroke Pines, Miramar, Davie, Coral Springs, Cooper City, Sunshine Ranches, Hallandale, Surfside, Miami Beach, Sunny Isles, Normandy Isles, Coral Gables, Hialeah, Golden Beach ,Kendall,sunrise, coral springs, parkland,pompano, boca raton, palm beach, weston, dania beach, tamarac, oakland park, boynton beach, delray,lake worth,wellington,plantation | <urn:uuid:3cded8cb-432f-4c0a-9ed1-9319739e97f6> | CC-MAIN-2023-40 | https://jeffreydachmd.com/2019/03/atherosclerotic-plaque-infection-electron-microscopy/ | 2023-09-26T05:47:10Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.892947 | 12,408 |
I feel misled. Looking at the headlines, I watched. But there was no talk of: *Australia military tyranny via CCP proximity! *Jab recovery protocols! etc. Instead the entire 64 mins is a hard-to-understand re-read of a leftist article which details Red Chi spycraft in the US. He calls it a ‘deep dive’. That could have been accomplished by giving the link to that article, and actually talking about what your headlines stated. I’ve sent comments before but they never make it onto the site. I don’t think you like being called out. | <urn:uuid:69a81cfa-959d-4a71-b386-5c9ba041deb3> | CC-MAIN-2023-40 | https://jeffreyprather.com/china-kidnaps-spys-schools-usa/ | 2023-09-26T05:18:40Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.971998 | 126 |
Jennie Wood is a multi-award-winning author and musician currently living in Boston. They created the critically acclaimed, award-winning Flutter graphic novel series. Featured in The New York Times, Boston Globe, and on Law & Order: SVU, Flutter was named one of the best LGBTQ graphic novels of 2013 and 2015 by The Advocate. In November 2018, Dark Horse Comics published The Flutter Collection, all three volumes combined into one book. That collection won the Next Generation Indie Book award for best graphic novel. Jennie is also the author of the YA novel, A Boy Like Me, which was a Next Generation Indie Book awards finalist, an INDIEFAB Book of the Year finalist, and one of Foreword Reviews’ 10 Best Indie YA novels for 2014. Their work can be seen in several anthologies, including The New York Times best-selling, award-winning FUBAR anthologies, The New York Times best-selling and Eisner award-winning anthology Love is Love, the Harvey-nominated 27, A Comic Anthology, and John Carpenter’s Tales for a HalloweeNight.
Jennie’s latest graphic novel, Paper Planes, was published on August 22, 2023 by Maverick, Mad Cave Studios’ young adult imprint. The book is the story of two inseparable grade school friends sent to a summer camp for troubled kids in the aftermath of a tragic event that threatens their friendship. Paper Planes is the 2023 Next Generation Indie Book Award winner for Young Adult Fiction (12 – 16 years) and the 2023 IPPY Award Bronze Medal winner in Young Adult Fiction – General Category. You can find out more info about Paper Planes here.
July 25-28, 2024, Comic-Con International: San Diego, San Diego, CA | <urn:uuid:3b4ca370-d264-45ff-810b-bea305b6a99d> | CC-MAIN-2023-40 | https://jenniewood.com/about/ | 2023-09-26T06:23:47Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.933235 | 382 |
Industrial Chemical Pumps in Brooks County
Drum Pumps in Brooks,
For transfering and dispensing fluids.
Brooks County Small Centrifugal Pumps
Centrifugal pumps' high flow rates and capacity to handle large volumes of fluid are two of their main advantages. Additionally, they have a fairly simple design that is simple to maintain. Applications for Centrifugal pumps include water treatment, irrigation, oil & gas production, and chemical processing. Centrifugal pumps come in a variety of designs, including axial, mixed, and radial flow pumps. Each type has its own distinct set of qualities and is created for particular applications.
MSDB SERIES - MAGNETIC DRIVE, SEALLESS, Brooks County CENTRIFUGAL PUMPS
- Heads up to 300 feet (91.5m)
- Minimum flow rate is 1 gpm (.23m3/h)
- Sealless design improves reliability with no seal maintenance to perform or seal leaks
- High specific gravity handling – over 1.8
- Compact close-coupled design
- Engineered for corrosive fluids with polypropylene/Ryton© or PVDF/Ryton© construction
- Maximum working pressure up to 135 PSI (9.3 bar)
- Two stage versions contain two impellers, three stage versions contain three impellers
- High power neodymium magnetic drive system handles high specific gravity fluids
- Horizontal or vertical (with IEC motor only) installation
Small Centrifugal Pumps in Brooks,
High flow rates and capacity to handle large volumes of fluid!
Air-Operated Diaphragm Chemical Pumps in Brooks,
Helping Industrial Brooks displacement pump needs.
Brooks County Air-Operated Diaphragm Chemical Pump Designs & Their Advantages
Fluid-handling devices that employ air pressure to transfer fluids include air operated diaphragm chemical pumps. They are available in several designs, including single- and double-diaphragm models, ball valve layouts, and nonmetallic wetted component setups. These pumps are adaptable and reasonably priced. They can tolerate caustic or abrasive fluids, have high flow rates, and can prime themselves.
They can be used even if the liquid levels change because they are self-priming and can run dry without causing damage. Additionally, they require relatively little maintenance and can deliver a constant flow rate. Last but not least, because these pumps are air-operated, they are simple to install and use a small amount of electricity. | <urn:uuid:8eed6291-5f48-413b-94d6-de322b3bcfed> | CC-MAIN-2023-40 | https://jhprocess.com/county/industrial-filters-chemical-pumps-in-brooks-county-tx/ | 2023-09-26T06:52:59Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.901482 | 537 |
One of the top calls our counseling team receives is from parents who struggle with feelings of resentment, sadness, or anger because of a fractured relationship with their adult children. It’s heartbreaking.
It’s also common. A 2015 studyby Richard Conti of Kean University found that 43 percent of college students had been estranged from their parents at some point. Twenty-six percent reported extended estrangement.
When a parent/adult child relationship is fractured, the most effective solution is to redefine the boundaries. Boundaries are God’s way for us to live in freedom so that we can take control of our lives and better love Him and others.
We’re focusing on the parent/adult child relationship on our Focus on the Family Broadcast “Healing Parent and Adult Child Relationships” with our guest, author and psychologist Dr. John Townsend. He shares:
- Common ways the adult child contributes to the problem in the relationship – and how parents should respond.
- Common ways parents contribute to the rift in the relationship – and how the adult child should respond.
- Basic principles of boundaries, how to set them, and expectations for resistance from the other family member.
- Roadblocks to boundaries.
- Forgiveness and reconciliation.
- How to take your troubles to God to find freedom.
Boundaries create freedom, and freedom always finds its ultimate expression through love. “For you were called to freedom, brothers. Only do not use your freedom as an opportunity for the flesh, but through love serve one another. For the whole law is fulfilled in one word: “‘You shall love your neighbor as yourself’” (Gal. 5:13-14).
Before I close, I’d like to remind you about our end-of-year campaign here at Focus on the Family. Generous friends are matching every donation you make to this ministry. Which means your gift will go twice as far toward rescuing hurting marriages, equipping parents, and giving families hope.
With your gift of any amount, we’ll send you Dr. John Townsend’s book Boundaries: When to Say Yes, How to Say No to Take Control of Your Life. Visit our website for more information or call 1-800-A-FAMILY (232-6459). | <urn:uuid:6ba02a44-bd7b-4ac3-ab25-e0299ed30281> | CC-MAIN-2023-40 | https://jimdaly.focusonthefamily.com/healing-parent-and-adult-child-relationships/ | 2023-09-26T07:01:06Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.914961 | 485 |
|Wolfgang Werz, German Route 66 Association, and author
Jim Hinckley. Werz, and his wife Anja, are honorary
members of the Route 66 Association of Kingman.
This morning I kick things off with a hearty congratulations to everyone who worked to make this years Birthplace of Route 66 Festival a success. Based upon the recent feature published at Route 66 News, (link above) I would be willing to bet that the City of Springfield is quite pleased with the turn out.
|Historic Los Angeles|
The cornerstone of the Route 66 renaissance is the people, their passion, their generosity, their enthusiasm, and the camaraderie of a shared experience that transforms an event into a family reunion. If the organizers of an event can tap into this, if they have an understanding of what makes the Route 66 community unique and special, a Route event will be successful even if it is just a kazoo band on the corner and a park suitable for a large picnic.
Surprisingly, the successful utilization of the Route 66 renaissance as a catalyst for development has largely been limited to metropolitan pockets and small rural communities. That, however, may change in the near future as Scott Piotrowski and his team tackle the multitude of problems associated with creating a Route 66 festival (an international 90th anniversary celebration at the highways original western terminus)in the heart of historic Los Angeles.
Many of the templates used to transform communities such as Pontiac could be applied to towns along the Lincoln Highway, U.S. 50, or any historic or scenic road in America. However, what can not be duplicated is the passion, the zeal, and the camaraderie of the international Route 66 enthusiast. A European Lincoln Highway Festival with support from Lincoln Highway Associations in several countries is inconceivable.
The Lincoln Highway is historic and scenic. There is international interest in the road and the preservation of its unique attributes. Still, it is not Route 66, the Main Street of America.
From its inception, the double six has had the best press and publicity. From the Main Street of America campaign launched in 1927 to The Grapes of Wrath, a television show, Michael Wallis’s book that spawned the roads rebirth, and Cadillac commercials filmed on the highway for the Chinese market this road has served as center stage for almost a century of American societal evolution.
If people aren’t traveling Route 66, they are planning a trip on Route 66, sometimes for years. And they form associations of like minded people, and they develop tour companies to cater to those people, and they create events and festivals to celebrate the roads culture and history – in the Czech Republic, Tokyo, and Germany.
At the Miles of Possibilities conference in Edwardsville, Illinois in October, I will distill this a bit in my presentation about the 160 mile corridor in western Arizona. We will also be visiting with friends along the way, and joining in on the family reunion type festivities.
|A gathering of Route 66 enthusiasts and friends at
de Prael in Amsterdam.
Plans are tentative, but at this time we are thinking of making the return journey along sections of the Lincoln Highway for a comparative study, and to visit with friends such as recent Wyoming transplant Greg Hasman. This may be subject to change as early November isn’t the ideal time for a trip across the northern plains. Of course January isn’t the optimum time for touring the Netherlands and Belgium but we did it and had a grand time because of the people, the friends made through shared Route 66 adventures. | <urn:uuid:25936073-f785-4302-9356-1e680d37f195> | CC-MAIN-2023-40 | https://jimhinckleysamerica.com/2015/08/19/good-friends-good-times-the-planning-of-adventures-and-a-hearty-congratulations/ | 2023-09-26T06:36:15Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.953349 | 741 |
When you make that bold decision to invest in your living space, what you are basically investing in is yourself. Be that as it may, sometimes you just become really unsure whether it’s really worth it. Especially, in those moments when there are other needs begging for your financial attention. YES! It is worth investing in your living space. Beyond giving an aesthetic appeal, let’s consider 5 reasons why you should continue or consider investing in your living space. Meanwhile, a living space is the amount of space available within a house that a person can occupy or reside.
- Improves your overall health and air quality
- To invest in a good living space inspires
- It improves your level of productivity
- If you invest in your space, people feel comfortable
- It could be functional
Improves your overall health and air quality
Covid 19 has taught the whole human race to be more conscious of our environment. From regular sanitization of the environment, to hands, railings etc. Though as an interventive measure, it is still useful to pay kin attention to how we organise our environment. Investing in your living space will not only improve the aesthetic and waoh your guests, it will also improve your wellbeing. Beyond aesthetics, selectively investing in nature that improves the quality of air in your environment can have an immeasurable benefit to your health and that of those around you. Having real plants in your space improves the quality of the air in that environment. Some of these plants include, Areca palm, Peace Lily
To invest in a good living space inspires
A well invested-in living space is not only beautiful, it also inspires. As humans, we are sometimes faced with so many challenges. Other times we are just too overwhelmed by all that is going on around us that we just can’t think straight. At times like this, a living space that has been well invested in could be one of many rescues to escape this existential crisis. A beautifully adorned living space is capable of removing sorrows that cover our minds and spirit.
When we play with aesthetic objects or shapes of beauty, It palettes the pall of gloom from our spirit. Check out how I meditate and set up my space. The good thing is, it doesn’t even cost a life fortune to achieve this. If you check on pinterest, you will find extraordinarily less expensive ideas to upgrade your space. You can start little by little, by stocking things that inspire you or can easily reconnect you to your energy.
It improves your level of productivity
An inspired soul is a productive mind. When your environment inspires you, it’s likely to increase productivity, especially if you work from home. Even when you don’t work from home, the energy received from your living space can be taken to your office the next morning. In that, it is conducive and makes your stay comfortable. For somebody working from home, you don’t want to stay in an environment that sucks your energy. Alight from the bandwagon who says living spaces are just for resting your head at night. It is your temple, and temples, they say, should be kept clean and good looking. More often than not, it affects your connection with you.
If you invest in your space, people feel comfortable
Not only will investing in your living space increase your level of productivity, it also says a lot about you. Of course we should care less about the opinions others make about us or their judgments. Nevertheless, if you have fully reflected who you are or who you want to become within our space, you feel more confident to allow visitors in.
Like a friend would say, where you stay or the condition of your living space either confers an honour on you or removes it. Some people might just avoid coming to your place because they do not feel it is comfortable or conducive. Oftentimes, what makes a great deal of difference could be little things like to invest in good air fresheners. To feel at home in your own living space and feel confident to invite guests, means you have to invest in it.
It could be functional
A typical example of something to invest in that could be functional is good lighting. A good lighting in your space would not only set a good mood but enhance the beauty and elegance of the room. It could serve as a good item during one of those zoom meetings. You know, it could become functional. The arrangement of your furniture and other items coil actually creates a better flow of movement within your space. Reducing clumsiness would make it easier to clean regularly.
Huge money is needed to invest in your living space – A myth
There is a myth that you need to have a lot to invest in your living space, well that’s not true. There are people with money who just don’t have the thought that they should. Such people can as a matter of fact buy frivolous items. Such people don’t mind hanging their expensive bags on nails put against the wall, hanging their expensive clothes on rope, instead of getting a decent wardrobe. Sometimes the investment needed in your living space is time to tidy up.
What it takes most times to invest in your living space is the intention to do soJoadre
In summary, all it takes most times to invest in your living space is recognition, acknowledgement and intentionality. Because after recognition, you need intentionality to execute an action. And you don’t have to go all out at once, you can do it little by little, one step at a time.
Meanwhile, we have developed a unique app to bring together on one platform – business education that is relevant to our global economy, data information to guide you and a community of both international partners/investors and Nigerian entrepreneurs. The android version is ready for those with android smartphones – downloading right here. An IOS version is on its way. Want to stay connected to know when we have opportunities or release the IOS version of the app so that you can join the tribe? Kindly sign up to our newsletter.
Thank you for reading to the end. | <urn:uuid:8bdef013-5d57-4fa9-b370-67fb7c4dff12> | CC-MAIN-2023-40 | https://joadre.com/5-reasons-to-invest-in-your-living-space/ | 2023-09-26T05:31:04Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.955876 | 1,270 |
Senior Data Engineer / Software Engineer
Asgard.ai is a platform that revisits the way sales & marketing teams tackle B2B prospecting to help them sell more, faster.
With our solution, instead of prospecting blindly, our customers can identify the companies most likely to buy their product and use our actionable insights to be more efficient when they reach out.
Our algorithms scan millions of data points looking for the digital footprints companies leave on the web in order to qualify these companies and identify buying intent signals.
Asgard.ai is founded by alumni of Centrale Lille, and Les Ponts / ENS, each with several years of experience in machine learning and natural language processing.
We are a fast-growing startup based in Paris and accelerated by Techstars. We are already working with 10+ customers and among them, some of the most brilliant growth & sales teams in France.
WHAT YOU WILL DO
We are looking for a senior data engineer ready to craft our product with us and ready to embark on an exciting adventure to make B2B sales prospecting great again.
You will have the unique opportunity to join us as our first employee and make a tremendous impact in the company! You will work closely with our CTO, contribute to major product and technical decisions, and set the standards for your future teammates.
Among your missions, you will:
- Design, build and maintain complex data pipelines
- Improve and scale our machine learning and NLP services: entity linking and matching, recommendation, …
- Build and manage crawlers & scrapers
- Build integrations with CRMs and Sales automation tools
- Design, develop, and improve API features
- Improve our internal back-office tools: dashboards, annotation tools, data validation, …
- Define and improve the development standards and processes at Asgard
- Help recruit and onboard your future teammates
- You have 5+ years of experience contributing to a software engineering team
- You have a good knowledge of Cloud Providers (GCP / AWS); MongoDB; ElasticSearch; Docker
- You have experience dealing with real-time data acquisition & data processing
- You have some knowledge of queue systems, Pub/Sub, distributed processing for intensive & reliable data pipelines
- You value ownership and knowing what questions to ask very highly—the ability to take an idea through all the stages from conception to shipping a product
- You are curious, resilient, pragmatic, passionate, and open to new ideas
- You are an excellent and humble engineer who is still willing to grow and learn new topics and skills
- You have empathy for others and an eagerness to share your knowledge and expertise with your colleagues and the general public
- You have excellent written/spoken communication skills
- You speak English fluently
- Be kind, humble & trustworthy.
- Proactively seek out ways to learn and grow every day
- Always run the extra mile
- Choose positivity and ambition
Offices rue de Rocroy, 75010 Paris shared with 3 other startups of the Techstars 2019 promotion | <urn:uuid:e7847643-ff43-4839-94df-8689511089f6> | CC-MAIN-2023-40 | https://jobs.techstars.com/companies/asgard-2/jobs/27331057-senior-data-engineer-software-engineer | 2023-09-26T06:41:54Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.917439 | 681 |
Security Manager at Newmont Mining Corporation
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- Company: Newmont Mining Corporation
- Location: Ghana
- State: Ghana
- Job type: Full-Time
- Job category: Newmont Inc Jobs in Ghana - Security Jobs in Ghana
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Newmont Mining Corporation is a leading global gold producer with key assets in Nevada, Peru, Australia, Ghana and Suriname.
Newmont’s Africa Operations holds two gold mining operations in Ghana: the Ahafo Mine located in the Brong-Ahafo region and the Akyem Mine located in the Eastern region. There is also near mine exploration and development focus in Ghana to annually replace gold reserves. Newmont Africa also has early-stage exploration programs in the African countries of Ethiopia and Morocco.
Our Africa operations employ approximately 5,900 employees and contractors, with the majority working at the Ahafo Mine. We offer an unparalleled blend of opportunity and career satisfaction with all the benefits you would expect from a global company. This, combined with our growth opportunities, makes Newmont a great company to work.
Our Akyem and Ahafo mines have made significant sustainable community development investments in our host communities. These include establishing Development Funds at our Akyem and Ahafo operational areas with each mine contributing US$1 per ounce of gold sold and 1% of net pre-tax annual profit into its community development fund.
The only gold company listed in the S&P 500 index, Newmont in 2007 became the first gold company selected to be part of the Dow Jones Sustainability World Index. Newmont’s industry leading performance is reflected through our Africa operations’ high standards in environmental management, health and safety for our workforce and creating value and opportunity for our employees, host communities and Newmont’s shareholders.
ABOUT THIS ROLE:
- Leads all elements of the Ahafo South operational security in accordance with established Newmont policies and procedures and to apply the best practices of industrial security (guarding and security technology) to the protection of the company personnel, contractors, visitors, assets, processes, property and product.
- This role will support, implement and manage the Newmont security strategy on site, in the region and throughout the organization.
IN THIS ROLE YOU WILL:
Threat and Risk Management/Asset Protection
- Conduct, refine and maintain Security Threat Risk Assessments (TRA), Security Vulnerability Assessments (SVA), VPSHR Risk Assessments, People Threat Management Assessments and appropriate Mitigation Action Plans for site departments.
- Set performance metrics for TRA/SVA/VPSHR Mitigation Action Plans.
- Identify staffing needs and supervise all aspects of the security function for the site and plan for LOM.
- Manage sophisticated security technologies systems, including but not limited to drone platforms, non-lethal ant-ASM counter-measures and detection systems.
- Strategically manage and oversee the deployment of security personnel, contracted guards and security technologies in a dynamic threat environment.
- Develop and implement Ahafo South’s security awareness programs.
- Plan for emergency preparedness and contingencies, and function as a crisis management team member.
- Review and maintain current Emergency Evacuation Tactical and Trigger Action plans for the site and implement new planning format in conjunction with Health and Safety and super HR Group (HR, Site Services, L&D).
- Plan, develop, and effectively implement training programs for internal and external security resources.
- Responsible for ensuring the training and development of the Security Department (employees and contractor staff) .
- Overall responsibility, management and oversight of contractor service security personnel.
- Establish and train Mobile Response Teams to include the identification of top performing contractor personnel and the deployment, integration and coordination with Public Security teams assigned to the units.
- Develop and train on technics and procedures, including the use of security specific personal protection equipment.
Planning and Reporting
- Prepare, perform analyses, report data to the Project Team, advice and provide support to the Project Leadership team on security matters.
- Develop, plan, implement an annual operations plan and ensure that security is incorporated in routine operations, forecasting, and strategic planning.
- Direct the Site Security budgeting process and manage budget by forecasting costs and monitoring expenditure to ensure cost control for the Project.
- Monitor the expenditure against the budget and confirming that spending occurs within the budgetary restrictions.
Relationship with Local Law Enforcement
- Liaising effectively with local and regional civil authorities, police, military, and community groups. Work closely with these groups, and with the Community Relations team, to address issues in the community before they become security problems.
- Responsibility for the security across a geographically large area, and including frequent interfacing with local elected officials, bureaucrats, and police and military officials.
- Drive safety culture in all aspects of security Project operations.
- Oversee that all work carried out adheres to Health and Safety standard operating procedures while delivering own prescribed outcomes and/or provide services by following Newmont’s Health and Safety systems and protocols.
- Co-ordinate the collection and analysis efforts targeted at providing timely and accurate assessments and warning of developing security threats.
- Manage Online Intelligence data collection and reporting.
YOUR TRAINING, SKILLS & EXPERIENCE CHECKLIST:
Formal Qualification (including Professional Registrations)
- Bachelor’s degree or equivalent certificate and experience in the fields of Security Management, Emergency management, Criminal Justice and Military Management or related discipline.
- Internationally recognized professional qualification and certification in Security, preferably ASIS or an equivalent International certification, e.g. Physical Security Professional (PSP) or Certified Protection Professional (CPP) or any equivalent international Security certification or studying towards such a certification.
- Knowledge of the organizational structure and management team.
- Knowledge of vendors and suppliers applicable to the department.
- Knowledge of internal administration and communication processes, procedures and systems.
- Knowledge of the organization’s invoicing and requisition processes, procedures and systems.
- Project knowledge and experience.
- Knowledge and experience within the security industry is required, mining and gold room security experience preferred.
- A minimum of 10+ years of relevant Africa work experience.
- Prior experience working with an expatriate work force.
- Strong Supervisory and Management experience.
- Demonstrated successes in working collaboratively in multi-cultural teams in expatriate settings. Work in developing countries, specifically in West Africa preferred.
- Strong analytical skills and business acumen to make sound decisions and recommendations.
- Deep knowledge of and experience in security technology systems, including access control systems and alarms, CCTV and certain advanced security technology systems
- Excellent interpersonal and organizational skills with good oral and written communication skills.
- Strong PC Skills, including MS Office, Word Excel, Power Point and outlook applications.
- Information monitoring and management skills.
- Reliable and Results driven.
- Detail focused.
- Team player.
- Specific vision abilities required by the job include close vision, distance vision, color vision, peripheral vision, and ability to adjust focus.
- Physical Demands: While performing the duties of the job, the employee is required to sit at a desk for extended periods, climb stairs, walk, hike and stand.
- Work Environment: The noise level in the office work environment is minimal. External noise levels may be loud at times.
Method of ApplicationSubmit your CV and Application on Company Website : Click Here
Closing Date : 25th March. 2022 | <urn:uuid:395a022f-300a-41fb-bf36-34ec9f69ac9c> | CC-MAIN-2023-40 | https://jobwebghana.com/jobs/security-manager-newmont-mining-corporation-2/ | 2023-09-26T06:49:12Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.891365 | 1,651 |
- This event has passed.
Guided Bee Walk
(Limited Tickets Remaining)
Join us on Saturday 20th May for ‘World Bee Day’ to celebrate the wonderful world of bees.
Hosted during ‘National Biodiversity Week’, this guided walk and talk will be led by Property Curator Matt Wheeler and wildlife expert Harm Deenen. You will learn all about the Johnstown apiary and the wild honeybees that inhabit the Estate as well as more unusual types of bee which are also important for pollination.
The walks take place at 11am (fully booked) and 2pm (1 space remaining) and places must be booked in advance.
Tours start promptly so please check in at reception at least 20 minutes before the start time of the tour. The tour will start from the museum courtyard.
All children should be accompanied by an adult.
- Tickets for this event are non-refundable and not for re-sale by third parties.
- Please take careful note of your date and time booked, as your event is a while away and it’s easy to forget or mix up dates.
- Please be aware that if you miss your time or day we may not be able to accommodate you at an alternative time. | <urn:uuid:8d98f003-20ec-4dd5-9d7c-2405d0b743f9> | CC-MAIN-2023-40 | https://johnstowncastle.ie/event/guided-bee-walk/ | 2023-09-26T06:26:32Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.945178 | 267 |
Summary prepared by Fielding M. McGehee III. If you use this material, please credit The Jonestown Institute. Thank you.
FBI Catalogue Music
FBI preliminary tape identification note: None
Date cues on tape: Early October 1978 (Pope John Paul has recently died)
Jimmy Carter, U.S. President
Walter Mondale, U.S. Vice President
Andrew Young, U.S. Ambassador to United Nations
Henry Kissinger, former National Security Adviser
Zbigniew Brzezinski, Carter’s national security advisor
Pope John Paul
Adolf Hitler, German Führer
Robert Mugabe, leader of Zimbabwean Patriotic Front in Rhodesia
Joshua Nkomo, leader of Zimbabwean Patriotic Front in Rhodesia
Agostinho Neto, President of Angola
Salvador Allende, assassinated president of Chile
David Rockefeller, founder of Trilateral Commission
Bob (several in Jonestown) (speaks)
Daren/Darren (likely either Janaro or Swinney) (speaks)
Marie (likely Exia Marie Duckett) (speaks)
Christa Amos (speaks)
Shirley Baisy (sings)
Tchabaka [Shawn] Baker (speaks)
Celeste Davis (speaks)
Jann Gurvich (speaks)
Shirley Hicks (speaks)
Lee Ingram (speaks)
Don Jackson (speaks)
Shawntiki (Verna Lisa) Johnson (speaks)
Teresa King (speaks)
Alfreda March (speaks)
Edward Moore (sings)
Cardell Neal (speaks)
Karl Newell (speaks)
Luigi Lemoyne Newman (speaks)
Albert Touchette (speaks)
Greg Watkins (speaks)
Deanna Wilkinson (sings)
Bible verses cited: None
(This tape was transcribed by Adrian Whicker. The editors gratefully acknowledge his invaluable assistance.)
The Jonestown community gathers for an evening of music and a short Q&A before the presentation of a movie.
There are three songs, followed by questions both from the news and on various political concepts read by Lee Ingram. The questions are admittedly easy, and several children participate in answering. As opposed to almost every tape in this collection, Jim Jones does not speak, nor is his name even mentioned.
Date of transcription: 6/12/79
In connection with the Federal Bureau of Investigation’s investigation into the assassination of U.S. Congressman LEO J. RYAN at Port Kaituma, Guyana, South America, on November 18, 1978, a tape recording was obtained. This tape recording was located in Jonestown, Guyana, South America, and was turned over to U.S. Officials in Guyana and subsequently transported to the United States.
On May 24, 1979, Special Agent (name deleted) reviewed the tape numbered 1B68-15. This tape was found to contain the following:
Contemporary music and a history lesson from an unknown male.
This tape was reviewed, and nothing was contained thereon which was considered to be of evidentiary nature or beneficial to the investigation of Congressman RYAN.
Differences with FBI Summary:
The summary is accurate and meets the FBI’s purposes.
Tape originally posted January 2022. | <urn:uuid:fb82626c-4ac2-4433-b061-bbea4bbbf30b> | CC-MAIN-2023-40 | https://jonestown.sdsu.edu/?page_id=113292 | 2023-09-26T06:03:06Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.933604 | 738 |
As we’re preparing for a new school year on the North Shore of Massachusetts many of us are already overwhelmed with checklists, school supply lists, and homework assignments. But have you considered the important estate planning homework that’s often overlooked in the back-to-school chaos?
Estate Planning for Young Adults: The Legal Shift at 18
Once your child turns 18, they legally become an adult. This age milestone changes the nature of your legal relationship, meaning you may no longer have the same automatic rights to manage their finances or make medical decisions. With proper estate planning, however, you can ensure that you’re able to step in if they encounter an unexpected crisis.
The Need for a Durable Power of Attorney
A Durable POA is a legal document that allows your child to designate you, or another trusted individual, to manage their financial matters if they become unable to do so themselves. This could be due to a variety of circumstances such as a serious illness, accident, or even studying abroad. The term “durable” means that the POA remains in effect even if your child becomes incapacitated. This document allows you to handle tasks such as paying bills, managing bank accounts, applying for loans, and dealing with other financial matters on your child’s behalf.
It’s particularly crucial for college students who might be studying far from home, or even abroad, and may need assistance with financial transactions or issues that arise unexpectedly. For example, if your child is studying in a different country and their bank account gets frozen, having a Durable POA allows you to liaise with the bank and solve the problem without delay.
In the absence of a Durable POA, parents may find themselves unable to quickly and efficiently manage these issues, potentially causing undue stress and complications. That’s why it’s a good idea to consider this vital piece of your estate planning homework as your child prepares to head off to college.
Medical Decision Making: The Importance of Health Care Proxy
As children embark on their college journey, especially when they’re away from home, having a Health Care Proxy is crucial. It is a legal document that allows your adult child to appoint you, or another trusted individual, to make medical decisions on their behalf should they become incapacitated and unable to make such decisions themselves.
It’s worth noting that upon turning 18, your child is legally recognized as an adult. This means healthcare providers must respect their privacy and may not disclose medical information to anyone, including parents, without explicit consent. This situation can be distressing in an emergency, when fast and informed decision-making is essential.
A Health Care Proxy goes beyond providing access to medical information. If your child is unable to communicate due to an accident or serious illness, the person named in the Health Care Proxy (also known as the agent) has the authority to make medical decisions according to your child’s wishes. This could involve decisions about surgeries, medical procedures, or even end-of-life care.
For students studying on the North Shore of Massachusetts or in a different state or country, having a designated decision-maker who understands their medical history and personal wishes can be vital. This person can communicate directly with healthcare providers, navigate complex medical decisions, and ensure the treatment aligns with your child’s preferences. In the absence of a Health Care Proxy, you may need to go through a court process to obtain legal authority to make these decisions – a process that can be time-consuming and stressful during an already difficult time.
Providing Access to Health Records: HIPAA Release
The Health Insurance Portability and Accountability Act (HIPAA) ensures the privacy of a patient’s medical records. Once your child turns 18, you may not automatically have access to their medical information without a signed HIPAA Release. This document is crucial in allowing you to make informed decisions about your child’s healthcare if they are incapacitated.
Contact Your North Shore Estate Planning Professionals Today
Securing your child’s future can feel overwhelming, but it doesn’t have to be. At Jordan & White, LLC, we can guide you through the process of establishing these essential documents. Our approachable team understands the unique needs and concerns of families on the North Shore, ensuring you feel comfortable and informed throughout your estate planning journey.
Ready to complete your back-to-school estate planning homework? Call us today at 978-744-2811 or contact us online for help with your advance directive living will. We’re here to make estate planning less of a chore and more of an empowerment. Secure your peace of mind today. | <urn:uuid:616638cb-68c3-4812-8bc1-813b36b71a00> | CC-MAIN-2023-40 | https://jordanwhitellc.com/have-you-completed-your-back-to-school-estate-planning-homework/ | 2023-09-26T05:49:30Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.942726 | 964 |
‘It was an incredible mix of movement and singing that shocked the audience and gave depth to Dusapin’s composition, while uncovering the core intimacy of Stein’s relationship to her lover.’
‘To be sung in the top 5 operas to see in North America!’
Center for Contemporary Opera presents:
To Be Sung
“She is my delight one of it have to be as bright. Brightly in her with her to her may her for her call her leave it to her let her with her can she way lay way lay is all wrong way lay is a song sing song of be. Be polite. Give with all your might. Have her delight you which is fortunately for her to be for me to be for her to be for me to be for me for her for her to be me for me for her and she for me and come.” – Gertrude Stein
The opera To Be Sung by French composer Pascal Dusapin was written in 1997 on extracts from A Lyrical Opera Made By Two by American novelist and poet Gertrude Stein (1874 – 1946). Stein wrote her ‘opera’ during the first world war on the island of Mallorca. Far away from the war, Stein stayed on the island with her life partner Alice Babette Toklas and their dog Basket. Stein is infamous for her writings often described as unreadable and incomprehensible. Her modernist abstract, angular and tautological way of writing is perhaps best compared to the cubist paintings of Picasso, a dear friend of hers. Through use of rhythm and the play of sounds and words, Steins language is close to music. Stating that all meaning is absent in Steins writings would be false. Inspired by her own experiences she talked about the universal theme’s of human life, without ever being too concrete. To Be Sung in particular was conceived as a declaration of love to her wife Alice B. Toklas and written for their 20th anniversary. The piece is an erotic, exciting and very intimate idyll that describes the profound love between two women.
To be sung is performed by four women: three singing and one speaking. The women represent one single body. Two become one through love. Intimacy is made visible and sensible. The distinction between men and women becomes obsolete. It is a universal love that Stein speaks about. A love that seems to be only possible when it is shielded from an outside world, from war, from oppression and from social judgement. This forms simultaneously an utopic contradiction and perhaps the only livable possibility.
With To be Sung Dutch director Jorinde Keesmaat continues her collaboration with the Center of Contemporary Opera in New York. In 2016 she gave her American debut with Louis Andriessen’s Odysseus’ Women & Anaïs Nin. Pushing the boundaries of what music theatre can be, Jorinde Keesmaat developed a very own theatrical language with a profound physicality at it’s core. In To be sung she examines the theme of universal love and its place in our society today.
Music: Pascal Dusapin
Libretto: Gertrude Stein
Stage Director: Jorinde Keesmaat
Conductor: Sara Jobin
Set & Costume Design: Sammy van den Heuvel
Light: Abigail Hoke-Brady
Dramaturge: Koen Bollen
Speaker: Judith Skinner
Singers: Kristina Bachrach, Danielle Buonaiuto, Anna Trombetta
Irondale Theater, Brooklyn New York | <urn:uuid:380bb31b-3ae5-4d99-8fb1-bc9607ac3ae8> | CC-MAIN-2023-40 | https://jorindekeesmaat.nl/2018/07/09/to-be-sung-upcoming-opera/ | 2023-09-26T06:56:10Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.958297 | 764 |
Severe malaria incidence is approximately two million cases with nearly 430,000 deaths annually . It is a medical emergency characterized by multisystem disease with different clinical manifestations between adults and children. However, recent studies show that cerebral involvement, kidney dysfunction, and acidosis are independent predictors of mortality in both adults and children (Fig. 1) [2,3]. This is supported by a meta-analysis of children with severe malaria that found prognostic indicators with the strongest association with death to be acute kidney injury (AKI) (odds ratio 5.96, 95% confidence interval, CI: 2.9–12.11) and coma (4.83, 95% CI: 3.11–7.5) [4▪▪].
Cerebral malaria is a clinical syndrome of impaired consciousness associated with malaria in the absence of hypoglycemia, convulsions, drugs, and nonmalarial causes characterized by unrousable coma defined by a Glasgow Coma Score less than11 (adults) or Blantyre Coma Score less than 3 (children) [6–8]. Two large intervention trials in Asian adults and African children with severe malaria found that 54% of adult and 34% of pediatric patients had cerebral malaria [9,10]. AKI in severe falciparum malaria is caused by acute tubular necrosis and defined as a creatinine more than 265 μmol/l or urea more than 20 mmol/l . In adults with severe malaria, AKI develops in up to 40% of patients, whereas in children, the incidence is historically reported at approximately 10% [9,10]. As the WHO definition does not define AKI adequately for pediatric malaria, the reported incidence of AKI in children is likely underestimated. The recent Kidney Disease: Improving Global Outcomes (KDIGO) classification standardizes AKI for clinical practice and research . In adult severe malaria, 58% had AKI as defined by KDIGO, of whom 40% died, accounting for 71% of overall mortality [12▪]. Among children with severe malaria 46% had AKI as defined by KDIGO, of whom 12–24% died with increasingly severe AKI [13▪]. In two large multicenter studies, approximately 25% of children with severe malaria had increased blood urea nitrogen, accounting for roughly 50% of total deaths [10,14]. These studies imply that AKI complicating pediatric severe malaria has been previously underdiagnosed [13▪].
Notably, the majority of patients surviving these complications have complete recovery after appropriate treatment. The direct cause of coma and AKI complicating severe malaria are incompletely understood but likely share common pathophysiological mechanisms. This review will highlight recent developments in our understanding of the pathophysiologic and pathologic processes associated with cerebral malaria and malaria-associated AKI in addition to the clinical presentation, diagnosis and treatments of these complications.
Severe malaria is predominantly caused by Plasmodium falciparum because of its ability to induce infected red blood cell (RBC) cytoadherence to the vascular endothelium and consequent end-organ dysfunction. Other plasmodium species can cause severe disease and AKI , although their ability to cause coma is debated .
Parasites developing within the infected RBC transport P. falciparum erythrocyte membrane protein 1 (PfEMP1) to the RBC membrane functioning as a key ligand for cytoadherence . PfEMP1 is expressed on RBC protrusions, or ‘knobs’, that confer points of attachment to the endothelium. PfEMP1 is strain specific, encoded by a highly variable var gene family, which provides antigenic variation for immune evasion and differential endothelial receptor binding. CD36 is an endothelial receptor constitutively expressed on most vascular beds . The key endothelial receptor in the brain is intercellular adhesion molecule-1 . Recent studies have identified endothelial protein C receptor as an important receptor in the brain that binds to a specific PfEMP1 domain (CIDRα1) [19▪,20–22]. Cytoadhesion results in sequestration of parasitized RBCs in the capillaries and postcapillary venules causing heterogeneous blockage of the microcirculation and tissue hypoxia . In addition to flow obstruction by sequestered parasitized RBCs, microcirculatory flow is thought to be further compromised by increased rigidity of both infected and uninfected RBCs and clumping of infected RBCs (platelet-mediated autoagglutination) and uninfected RBCs adhering to infected RBCs (rosette formation) .
Direct visualization of microvascular obstruction is observed in the retina of adults and children with cerebral malaria, termed ‘malaria retinopathy’ [25,26]. Cerebral blood flow is not decreased in adults [27,28]. Intracranial pressure is often increased in children, but less so in adult patients [29,30]. Indirect assessment of sequestration via estimated total parasite biomass, measured by P. falciparum histidine rich protein 2, was shown to contribute to AKI in adults with severe malaria . Autopsy studies of adults and retinopathy-positive children dying from cerebral malaria show prominent sequestration in the brain microvasculature compared to adults with fatal noncerebral malaria and retinopathy-negative children [32,33]. Postmortem studies report sequestration of parasitized RBCs in renal glomerular and peritubular capillaries in adults and children [32,34].
Microvascular obstruction-induced tissue hypoxia is compounded by microvascular dysfunction [35,36] and increased oxygen demand [36,37]. In adults with cerebral malaria, there is endothelial and astroglial activation in the brain , with variable inflammatory responses and mild functional change to the blood–brain barrier [39,40]. In children with strictly defined retinopathy-positive cerebral malaria, breakdown of the endothelial barrier is observed particularly in areas of sequestration . Patterns of histopathological change within the brain in cerebral malaria vary between adults and children, with less inflammatory cellular infiltrates and edema in adult cases [41,42]. A recent pediatric autopsy study found that HIV coinfection influences histopathology, increasing the degree of platelet and monocyte infiltration around damaged microvasculature .
In a recent MRI study of similarly defined children, 35% had evidence of brain swelling most commonly in fatal cases implicating brainstem herniation as the cause of death . Another recent serial MRI study in India including adults and children found that 50% of patients had evidence of brain swelling with posterior vasogenic edema and vascular congestion in the basal nuclei [45▪]. All patients had rapid clinical improvement and radiological reversibility with hallmarks suggestive of posterior reversible encephalopathy syndrome. The exact cause of the brain swelling is yet unclear.
Studies of patients with severe malaria having AKI show reduced renal cortical blood flow , increased kidney size , and endothelial changes in both glomerular and peritubular capillaries on histopathology . Cell-free hemoglobin and lipid peroxidation markers are strongly associated with AKI and renal replacement therapy (RRT) requirement in adults with severe malaria [12▪]. In children with severe malaria, an elevated heme-to-hemopexin ratio was associated with hemoglobinuria, stage 3 AKI, and 6-month mortality [48▪].
There is an imbalance of proinflammatory and anti-inflammatory responses in severe malaria . The role of cytokines and chemokines in cerebral malaria has been recently reviewed . However, many of these studies are in the murine experimental cerebral malaria model, the relevance of which has been questioned . Conflicting evidence has emerged from human studies as to the association between cerebral malaria and levels of numerous cytokines such as tumor necrosis factor α (TNFα) [49,52–56]. Although cytokines and/or chemokines are clearly involved in the pathogenesis of malarial fever and may be associated with disease severity and/or cerebral malaria, it is not established that they are a cause of coma.
The role of cytokines and chemokines in the pathophysiology of AKI in severe malaria was recently highlighted. Plasma-soluble urokinase-type plasminogen activator receptor, a marker of immune activation, was independently associated with AKI and RRT requirement . Previously, it was shown that TNFα, but not inteleukin (IL)6 or IL6:IL10 ratio, was associated with AKI suggesting that TNFα may induce localized renal tubular cell injury .
The clinical presentation of cerebral malaria is diffuse symmetrical encephalopathy with fever and absent or few focal neurological signs. In children, coma can rapidly develop after fever onset (mean, 2 days) . In adults, coma is typically gradual with increasing drowsiness, confusion, obtundation, and high fevers (mean duration, 5 days). Convulsions are present in approximately 15% of adults and 80% of children with severe malaria [9,10] and frequently herald development of coma. Patients may recover full consciousness after a convulsion, thus transient postictal coma must be excluded . Multiple convulsions are common and up to 50% of comatose children have subclinical seizures or status epilepticus. Ocular funduscopic findings include vessel color change, macular and extramacular whitening, and white-centered retinal hemorrhages (Fig. 2).
Among survivors, the median time to coma recovery is roughly 24 h in children and 48 h in adults [9,10]. Retinal abnormalities resolve with no residual visual deficit. Neurologic sequelae occur in less than 1% of adults but up to 12% of children in the quinine-therapy era, including hemiplegia, cortical blindness, aphasia, and cerebellar ataxia . Studies suggest that neurologic deficits may reflect slow neurological recovery [10,60]. Postmalaria neurological syndrome is self-limiting ; however, longer term neurological sequelae, including cognitive deficits and epilepsy, are reported among children [62,63▪].
The majority of malaria patients have risk factors for developing AKI, including volume depletion, hypoalbuminemia, male sex, previous AKI, concomitant bacterial sepsis, blackwater fever (BWF), or comorbidity, such as, diabetes. Severe intravascular hemolysis and hemoglobinuria in severe malaria, with or without AKI, is known as BWF. Although oliguria clinically indicates decreased function with a prerenal component, up to 80% of patients with malaria have nonoliguric AKI [64–66]. Thus, the clinical diagnosis will capture established anuric AKI but will underdiagnose moderate AKI and delay diagnosis. AKI complicating severe malaria can be categorized into four groups:
- (1) Few severity criteria with prerenal AKI that resolves with fluids.
- (2) Several severity criteria including AKI that resolves without RRT.
- (3) Progressive AKI that resolves with antimalarial treatment and RRT.
- (4) Multiorgan dysfunction, often with anuric AKI and cerebral malaria, who die prior to or during RRT with hemodynamic shock and/or respiratory failure.
Any comatose patient with a history of fever and/or travel to malaria-endemic regions must be considered to have cerebral malaria until proven otherwise. In children, febrile convulsions should be distinguished from cerebral malaria, wherein coma will persist beyond 1 h after anticonvulsive treatment is administered. Absence of fever does not rule out malaria. Antimalarial treatment should not be delayed in severely ill patients if diagnostics are unavailable or delayed.
Parasitological diagnosis is by microscopy of stained thin and thick blood smears. A rapid diagnostic test for parasite antigens can be performed if microscopy is unavailable. Patients may have a low circulating parasitemia because of sequestration, thus a low parasitemia is not reassuring . In high-transmission settings, children with partial immunity tolerate higher parasitemia without severe symptoms and may be asymptomatic at low parasitemia. A parasitemia of more than 1 000 000/μl in African children with cerebral malaria is associated with fatal outcomes .
Funduscopy for malaria retinopathy improves specificity for diagnosis of cerebral malaria and is prognostic in patients with severe malaria [26,68,69] (Fig. 2). Alternative causes of coma must be ruled out including hypoglycemia, and bacterial, fungal, or viral meningoencephalitis. Lumbar puncture does not increase mortality in stable, comatose children with suspected cerebral malaria even when MRI brain swelling or papilledema is present [70▪].
There is no robust prognostic risk model or biomarker that can predict AKI or RRT requirement [71,72▪]. All patients with malaria should be considered at risk of developing AKI. To improve outcomes, early diagnosis and management is critical. AKI diagnosis requires quantification of creatinine (or urea) or observing low urine volume (<0.5 ml/kg/h) for 6 h (Fig. 3) [6,11]. Urine output is difficult to accurately assess in malaria endemic countries and may delay diagnosis. As the WHO creatinine threshold is not applicable to children, the diagnosis of AKI must be considered using all available patient data. The KDIGO AKI definition of a creatinine rise at least 1.5 times baseline is the current standard, and baseline creatinine can be back-calculated using the Modified Diet in Renal Disease (>19 years) or Swartz equation (≤18 years) [11,73].
The two key pillars of severe malaria treatment are prompt antimalarial treatment and supportive management. Adjunctive therapies targeted at the underlying pathophysiology are unproven.
Two landmark trials in patients with severe malaria definitively showed that intravenous artesunate reduced mortality by 35 and 23% in adults and children, respectively, compared to quinine [9,10]. Intravenous artesunate is now the first-line treatment for severe malaria as recommended by the WHO. Artemether and quinine are the second-line therapies . The mechanism of improved survival over quinine is the rapid cidal activity of artesunate on young ring forms, preventing parasite maturation and sequestration . Once the patient is able to take oral medication, and after a minimum of 24 h of artesunate, an oral artemisinin-based combination therapy can be initiated to complete the treatment.
Despite the best available artemisinin therapy for malaria, mortality remains unacceptably high and supportive management is key to reducing this. Comatose patients require endotracheal intubation with mechanical ventilation for airway protection. Rapid sequence intubation should be performed to prevent transient hypercapnia and increased intracranial pressure. Routine care should be implemented including regular turning, lateral positioning (‘recovery position’), and catheterization. Nasogastric tube insertion and suctioning may protect against aspiration, however, enteral feeding in nonintubated patients should be delayed (>60 h) because of increased risk of aspiration pneumonia .
The majority of children with cerebral malaria experience convulsions. Glucose replacement to ensure euglycemia and fever control with paracetamol are important. Prophylactic anticonvulsant therapy is not recommended. A randomized controlled trial (RCT) of phenobarbital in pediatric cerebral malaria showed increased mortality, likely caused by respiratory depression .
Fluid management and nephrotoxic drug avoidance are cornerstones for management of malaria-associated AKI. Cautious fluid management is important, as patients with AKI are not necessarily hypovolemic and are at high risk of developing pulmonary edema [78–81]. Rapid infusions may exacerbate intracranial hypertension and precipitate cerebral herniation. The large multicenter Fluid Expansion as Supportive Therapy study of African children with severe febrile illness showed a relative risk for death of 1.59 (95% CI: 1.10–2.31) with fluid bolus therapy among those with malaria . The WHO recommends individualized restrictive fluid management, keeping the patient slightly dry, using slow infusion of isotonic crystalloids . Patients with BWF require creatinine and hemoglobin monitoring as resulting severe anemia requires whole blood transfusion.
Treatment of malaria-associated AKI with RRT reduces mortality from 75 to 26% . In general, RRT is urgently indicated when biochemical disturbances and volume overload refractory to conventional therapy are present. The additional thresholds included in the WHO malaria guidelines are based on findings that anuria and elevated or rapidly rising creatinine are sensitive indicators for RRT [6,64]. As AKI in malaria rapidly progresses and is often compounded by multiorgan dysfunction, early RRT is recommended. Although intermittent hemodialysis and continuous venovenous hemofiltration have been shown to be superior to peritoneal dialysis in adults with severe malaria , in the absence of hemodialysis, life-saving peritoneal dialysis should be initiated if this is the only modality available . RRT has also been shown to be effective in the management of malaria-associated AKI in pediatric patients .
Many adjunctive therapies have been suggested, mainly driven by studies in murine experimental cerebral malaria. However, none has proven benefit in humans. Evidence for exchange transfusion and the more recently employed RBC exchange transfusion remains limited [85▪,86,87]. Mannitol [88,89], steroids [90,91], and monoclonal antibodies to TNF [54,56] are not recommended as treatments in cerebral malaria as studies show no benefits and potential harm. Furosemide and mannitol are ineffective in preventing and treating AKI and BWF, respectively, and may be harmful [92,93]. On the basis of the ability of paracetamol to inhibit hemoprotein-mediated AKI , a recent RCT of paracetamol in Bangladeshi adults with severe malaria found that acetaminophen improved kidney function and reduced the development of AKI, particularly in patients with high cell-free hemoglobin levels at enrollment [95▪,96]. Larger studies of paracetamol in adults and children with malaria are currently ongoing to further assess this renoprotective effect.
Cerebral malaria and AKI complicating severe malaria are prognostic for mortality in both adults and children. Microvascular obstruction and endothelial dysfunction are common mechanisms for both of these complications. Future study of adjunctive therapies should target reducing sequestration, improving endovascular function, and reducing hemoglobin-mediated oxidative stress.
Financial support and sponsorship
This work was supported by the Wellcome Trust of Great Britain.
Conflicts of interest
There are no conflicts of interest.
REFERENCES AND RECOMMENDED READING
Papers of particular interest, published within the annual period of review, have been highlighted as:
▪ of special interest
▪▪ of outstanding interest
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34. Nguansangiam S, Day NP, Hien TT, et al. A quantitative ultrastructural study of renal pathology in fatal Plasmodium falciparum
malaria. Trop Med Int Health 2007; 12:1037–1050.
35. Yeo TW, Lampah DA, Gitawati R, et al. Recovery of endothelial function in severe falciparum malaria: relationship with improvement in plasma L-arginine and blood lactate concentrations. J Infect Dis 2008; 198:602–608.
36. Yeo TW, Lampah DA, Kenangalem E, et al. Impaired skeletal muscle microvascular function and increased skeletal muscle oxygen consumption in severe falciparum malaria. J Infect Dis 2013; 207:528–536.
37. Day NPJ, Phu NH, Bethell DP, et al. The effects of dopamine and adrenaline infusions on acid-base balance and systemic haemodynamics in severe infection. Lancet 1996; 348:219–223.
38. MacPherson GG, Warrell MJ, White NJ, et al. Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration. Am J Pathol 1985; 119:385–401.
39. Davis TM, Suputtamongkol Y, Spencer JL, et al. Measures of capillary permeability in acute falciparum malaria: relation to severity of infection and treatment. Clin Infect Dis 1992; 15:256–266.
40. Warrell DA, Looareesuwan S, Phillips RE, et al. Function of the blood-cerebrospinal fluid barrier in human cerebral malaria: rejection of the permeability hypothesis. Am J Trop Med Hyg 1986; 35:882–889.
41. Medana IM, Day NP, Sachanonta N, et al. Coma in fatal adult human malaria is not caused by cerebral oedema. Malar J 2011; 10:267–280.
42. Ponsford MJ, Medana IM, Prapansilp P, et al. Sequestration and microvascular congestion are associated with coma in human cerebral malaria. J Infect Dis 2012; 205:663–671.
43. Hochman SE, Madaline TF, Wassmer SC, et al. Fatal pediatric cerebral malaria is associated with intravascular monocytes and platelets that are increased with HIV coinfection. MBio 2015; 6:e01390–e01415.
44. Seydel KB, Kampondeni SD, Valim C, et al. Brain swelling and death in children with cerebral malaria. N Engl J Med 2015; 372:1126–1137.
45▪. Mohanty S, Benjamin LA, Majhi M, et al. Magnetic resonance imaging of cerebral malaria patients reveals distinct pathogenetic processes in different parts of the brain. mSphere 2017; 2:e00193–e00217.
46. Sitprija V, Vongsthongsri M, Poshyachinda V, Arthachinta S. Renal failure in malaria: a pathophysiologic study. Nephron 1977; 18:277–287.
47. Atalabi OM, Orimadegun AE, Adekanmi AJ, Akinyinka OO. Ultrasonographic renal sizes, cortical thickness and volume in Nigerian children with acute falciparum malaria. Malar J 2013; 12:92–98.
48▪. Elphinstone RE, Conroy AL, Hawkes M, et al. Alterations in systemic extracellular heme and hemopexin are associated with adverse clinical outcomes in ugandan children with severe malaria. J Infect Dis 2016; 214:1268–1275.
49. Day NP, Hien TT, Schollaardt T, et al. The prognostic and pathophysiologic role of pro- and antiinflammatory cytokines in severe malaria. J Infect Dis 1999; 180:1288–1297.
50. Dunst J, Kamena F, Matuschewski K. Cytokines and chemokines in cerebral malaria pathogenesis. Front Cell Infect Microbiol 2017; 7:1–16.
51. Craig AG, Grau GE, Janse C, et al. The role of animal models for research on severe malaria. PLoS Pathog 2012; 8:1–9.
52. Grau GE, Taylor TE, Molyneux ME, et al. Tumor necrosis factor and disease severity in children with falciparum malaria. N Engl J Med 1989; 320:1586–1591.
53. Kwiatkowski D, Hill AV, Sambou I, et al. TNF concentration in fatal cerebral, nonfatal cerebral, and uncomplicated Plasmodium falciparum
malaria. Lancet 1990; 336:1201–1204.
54. Kwiatkowski D, Molyneux ME, Stephens S, et al. Anti-TNF therapy inhibits fever in cerebral malaria. Q J Med 1993; 86:91–98.
55. Shabani E, Ouma BJ, Idro R, et al. Elevated cerebrospinal fluid tumour necrosis factor is associated with acute and long-term neurocognitive impairment in cerebral malaria. Parasite Immunol 2017; 39:1–9.
56. van Hensbroek MB, Palmer A, Onyiorah E, et al. The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria. J Infect Dis 1996; 174:1091–1097.
57. Lieberthal W, Koh JS, Levine JS. Necrosis and apoptosis in acute renal failure. Semin Nephrol 1998; 18:505–518.
58. Lewallen S, Taylor TE, Molyneux ME, et al. Ocular fundus findings in Malawian children with cerebral malaria. Ophthalmology 1993; 100:857–861.
59. Brewster DR, Kwiatkowski D, White NJ. Neurological sequelae of cerebral malaria in children. Lancet 1990; 336:1039–1043.
60. van Hensbroek MB, Palmer A, Jaffar S, et al. Residual neurologic sequelae after childhood cerebral malaria. J Pediatr 1997; 131:125–129.
61. Nguyen TH, Day NP, Ly VC, et al. Postmalaria neurological syndrome. Lancet 1996; 348:917–921.
62. Birbeck GL, Molyneux ME, Kaplan PW, et al. Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study. Lancet Neurol 2010; 9:1173–1181.
63▪. Brim R, Mboma S, Semrud-Clikeman M, et al. Cognitive outcomes and psychiatric symptoms of retinopathy-positive cerebral malaria: cohort description and baseline results. Am J Trop Med Hyg 2017; 97:225–231.
64. Tran TMT, Phu NH, Vinh H, et al. Acute renal failure in patients with severe falciparum malaria. Clin Infect Dis 1992; 15:874–880.
65. Aloni MN, Nsibu CN, Meeko-Mimaniye M, et al. Acute renal failure in Congolese children: a tertiary institution experience. Acta Paediatr 2012; 101:e514–e518.
66. Esezobor CI, Ladapo TA, Osinaike B, Lesi FE. Paediatric acute kidney injury in a tertiary hospital in Nigeria: prevalence, causes and mortality rate. PLoS One 2012; 7:1–6.
67. White NJ, Krishna S. Treatment of malaria: some considerations and limitations of the current methods of assessment. Trans R Soc Trop Med Hyg 1989; 83:767–777.
68. Beare NA, Southern C, Chalira C, et al. Prognostic significance and course of retinopathy in children with severe malaria. Arch Ophthalmol 2004; 122:1141–1147.
69. Taylor TE, Fu WJ, Carr RA, et al. Differentiating the pathologies of cerebral malaria by postmortem parasite counts. Nat Med 2004; 10:143–145.
70▪. Moxon CA, Zhao L, Li C, et al. Safety of lumbar puncture in comatose children with clinical features of cerebral malaria. Neurology 2016; 87:2355–2362.
71. Hanson J, Hasan MM, Royakkers AA, et al. Laboratory prediction of the requirement for renal replacement in acute falciparum malaria. Malar J 2011; 10:217–225.
72▪. van Wolfswinkel ME, Koopmans LC, Hesselink DA, et al. Neutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury. Malar J 2016; 15:464–471.
73. Kaddourah A, Basu RK, Bagshaw SM, Goldstein SL. Epidemiology of acute kidney injury in critically ill children and young adults. N Engl J Med 2017; 376:11–20.
74. World Health Organization. World Health Organization Guidelines for the treatment of malaria. Third edition. Geneva: World Health Organization, 2015. Available from: http://www.who.int/malaria/publications/atoz/9789241549127/en/
75. ter Kuile F, White NJ, Holloway P, et al. Plasmodium falciparum
: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria. Exp Parasitol 1993; 76:85–95.
76. Maude RJ, Hoque G, Hasan MU, et al. Timing of enteral feeding in cerebral malaria in resource-poor settings: a randomized trial. PLoS One 2011; 6:1–7.
77. Crawley J, Waruiru C, Mithwani S, et al. Effect of phenobarbital on seizure frequency and mortality in childhood cerebral malaria: a randomised, controlled intervention study. Lancet 2000; 355:701–706.
78. Hanson J, Anstey NM, Bihari D, et al. The fluid management of adults with severe malaria. Crit Care 2014; 18:642–650.
79. Hanson J, Lam SW, Mohanty S, et al. Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines? Malar J 2011; 10:342–349.
80. Hanson JP, Lam SW, Mohanty S, et al. Fluid resuscitation of adults with severe falciparum malaria: effects on acid-base status, renal function, and extravascular lung water. Crit Care Med 2013; 41:972–981.
81. Nguyen HP, Hanson J, Bethell D, et al. A retrospective analysis of the haemodynamic and metabolic effects of fluid resuscitation in Vietnamese adults with severe falciparum malaria. PLoS One 2011; 6:1–9.
82. Phu NH, Hien TT, Mai NT, et al. Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam. N Engl J Med 2002; 347:895–902.
83. Mishra SK, Mahanta KC. Peritoneal dialysis in patients with malaria and acute kidney injury. Perit Dial Int 2012; 32:656–659.
84. Asinobi AO, Ademola AD, Alao MA. Haemodialysis for paediatric acute kidney injury in a low resource setting: experience from a tertiary hospital in South West Nigeria. Clin Kidney J 2016; 9:63–68.
85▪. Calvo-Cano A, Gomez-Junyent J, Lozano M, et al. The role of red blood cell exchange for severe imported malaria in the artesunate era: a retrospective cohort study in a referral centre. Malar J 2016; 15:216–222.
86. Gyr K, Speck B, Ritz R, et al. Cerebral tropical malaria with blackwater fever. A current diagnostic and therapeutic problem [in German]. Schweiz Med Wochenschr 1974; 104:1628–1630.
87. Tan KR, Wiegand RE, Arguin PM. Exchange transfusion for severe malaria: evidence base and literature review. Clin Infect Dis 2013; 57:923–928.
88. Mohanty S, Mishra SK, Patnaik R, et al. Brain swelling and mannitol therapy in adult cerebral malaria: a randomized trial. Clin Infect Dis 2011; 53:349–355.
89. Namutangula B, Ndeezi G, Byarugaba JS, Tumwine JK. Mannitol as adjunct therapy for childhood cerebral malaria in Uganda: a randomized clinical trial. Malar J 2007; 6:138–143.
90. Hoffman SL, Rustama D, Punjabi NH, et al. High-dose dexamethasone in quinine-treated patients with cerebral malaria: a double-blind, placebo-controlled trial. J Infect Dis 1988; 158:325–331.
91. Warrell DA, Looareesuwan S, Warrell MJ, et al. Dexamethasone proves deleterious in cerebral malaria. A double-blind trial in 100 comatose patients. N Engl J Med 1982; 306:313–319.
92. Ho KM, Power BM. Benefits and risks of furosemide in acute kidney injury. Anaesthesia 2010; 65:283–293.
93. Ho KM, Sheridan DJ. Meta-analysis of frusemide to prevent or treat acute renal failure. Br Med J 2006; 333:420–425.
94. Boutaud O, Moore KP, Reeder BJ, et al. Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure. Proc Natl Acad Sci USA 2010; 107:2699–2704.
95▪. Plewes K. Intravascular haemolysis, oxidative stress and acute kidney injury in severe falciparum malaria [DPhil]. University of Oxford, (Nuffield Department of Medicine; Green Templeton College.) University of Oxford, 2016
96. Plewes K, Kingston HWWT, Ghose A, et al. editors. Paracetamol as adjunctive treatment in severe and moderately severe falciparum malaria: An open label, randomised controlled trial. In: American Society of Tropical Medicine and Hygiene 65th Annual Meeting. Philadelphia, Pennsylvania, 2015.
97. Maude RJ, Plewes K, Dimock J, Dondorp AM. Low-cost portable fluorescein angiography. Br J Ophthalmol 2011; 95:1213–1215. | <urn:uuid:4bcf90cf-4d36-4895-a96d-e5a064b6e986> | CC-MAIN-2023-40 | https://journals.lww.com/co-infectiousdiseases/Fulltext/2018/02000/Pathophysiology,_clinical_presentation,_and.11.aspx | 2023-09-26T06:07:36Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.821877 | 9,187 |
As a premier company in Orange County specializing in Homeowners Associations and commercial roofing services, we are dedicated to providing customer service that is second to none. Whether you have roof leak repairs needed or just need to have your old or damaged roofs replaced, we offer the best services with competitive prices.
If you control the affairs of apartments, condominiums or homeowners associations, you'll value our quick, dependable service. We are here to serve you, to answer any questions that you might have and to make sure we can save you the most amount of money possible. For promptness and reliability, our friendly staff in on call 24-hours a day to respond to any emergency situations.
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Managed by Dove Association Management - Monarch Manor H.O.A. in Fullerton - Reroofing completed to all the flat roofs in the complex
We strive to be in constant communication with our customers until the job is done. To get a free quote, or if you have questions or special requests, just drop us a line. We look forward to serving you!
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Saturday - Sunday: Closed | <urn:uuid:8e9cc7ef-7214-4f6b-92eb-c4655bbb31cf> | CC-MAIN-2023-40 | https://jphoaroofing.com/ | 2023-09-26T06:46:52Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.945098 | 291 |
Want to work with us? Current job vacancies:
Physiotherapist: Employed Full / Part Time
To commence November / December 2023
Salary £26,000 – £40,000 pro rata, dependent upon experience
Location: Meltham, Holmfirth, West Yorkshire HD9 4AF
Hours: Negotiable – minimum 20 per week, maximum 40 per week – working hours to be discussed but could include evenings and Saturdays.
We have an opening for a physiotherapist to join our team in our modern and relaxing small private physiotherapy clinic in Yorkshire. Based in the quaint village of Meltham, nestled between the hills of the Peak District and Pennine National Parks, this is the ideal base to explore Yorkshire, Lancashire, and Greater Manchester. The cities of Manchester, Sheffield, Leeds and York are less than an hour away, and yet we are surrounded by countryside and historic towns and villages such as Holmfirth, Halifax, Slaithwaite and Marsden.
Our clinic has been in business for over 20 years, providing quality physiotherapy for the local community. We have a wide demographic, including working with athletes, the elderly, women’s health, children, road traffic accidents, and occupational injuries. Whilst mostly musculoskeletal in nature, your caseload would provide variety and development opportunities. We are passionate about continuous development, and invest in staff training and technology including shockwave, diagnostic ultrasound, women’s pelvic health, and acupuncture. We have full-time administrative support to minimise the burden of paperwork! We want you to use your time doing what you do best – providing hands-on patient-centred assessment and treatment, working with your patients to put together realistic treatment plans, and following their journey all the way from assessment to achieving their goals. At JRM Physiotherapy you get the opportunity to spend time with your patients, providing the quality physiotherapy every patient deserves, and building a supportive relationship based on trust and professional expertise.
We work as a team – welcoming initiative and innovative ideas from the whole team. We share best practice at regular peer review sessions, and also hold team social events. In the last year our team have worked together to develop a community outreach project, running Falls Prevention classes for the local community. We are interested in other ways to provide our services to the wider community and you would have a key role to play in this activity.
We are a Quality Assured Clinic with Physio First – which means all our physiotherapists have collected and submitted audit data about their treatment outcomes to an independent body and been assessed as Quality Assured Practitioners. We would expect any successful applicant to join Physio First and submit Data for Impact to work towards Quality Assured Practitioner status.
- Current HCPC Registration as a Physiotherapist (essential and non-negotiable)
- Member of Chartered Society of Physiotherapy (essential and non-negotiable)
- At least two years’ post-graduation experience (desirable)
- Further training in women’s pelvic health / Mummy MOT (desirable)
- Confident in managing own (mainly MSK) caseload and diary management (essential)
- Right to work in the UK (we are unable to offer visa sponsorship at present)
Other key info
- 20 days holiday + all English bank holidays
- employers pension
- £500 annual CPD training allowance
- uniform provided
- company social events
- admin support
- free on-site parking
How to apply
For more info, or to apply, send your CV and cover email telling us why you would be the right person for Team JRM to email@example.com
Shortlisted candidates will be invited to interview (face-to-face or via video link). | <urn:uuid:fbf93970-f987-428b-9674-22d7285defb2> | CC-MAIN-2023-40 | https://jrmphysio.com/jobs/ | 2023-09-26T05:36:48Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.945148 | 810 |
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Green Label 50/50 6mg, ne sjecam se na koliko sam ju miksala
odlicna tekucina, iako bi se i ona mogla malo doratiti 🙂 u svakom slucaju narucila bih ju opet 🙂
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Here Are Some Of The Incredible People Coming To Junket 2017
What a guest list.
It’s happening again! Junket, our annual ~unconference~ that brings together Australia’s best and brightest young minds to learn, innovate, inspire and create solutions that will have a positive impact on our lives, is back for another year.
For two days, we’ll gather at QT Hotel (shout out to our hosts Visit Canberra), to chat about some of the problems facing young people at home and abroad, and how we can create practical solutions for them. We’ll also just have a heap of fun with some of the most exciting, creative young minds in the country.
So Who’s Coming?
We have a stellar line up attending Junket this year, including Logie award-winning actress Miranda Tapsell and her podcasting partner in crime, actress Nakkiah Lui. Also coming along will be radio host Alex Dyson, video editor Huw Parkinson (who creates those incredible Insiders videos that go viral every week), and musician and novelist Holly Throsby.
Joining them will be our favourite pop artist Frida Las Vegas; former Matilda and current LGBTIQ+ activist Sally Shipard; GetUp’s Sally Rugg, who has been leading the fight for marriage equality for years; comedian and viral video star Tanya Hennessy; Poet, rapper and author Omar Musa; “Black Comedy” star Ian Zaro and design entrepreneur Allen Liao.
But that’s not all. We’ve got a bunch of Young Australian of the Year nominees, awesome activists, authors, entrepreneurs, poets, actors, economists, musicians, journalists, scientists, CEOs, social workers and entertainers and DJs coming along, and they’ve all got a heap of great ideas!
What Will They Be Talking About?
All of our delegates will be coming to Canberra with something to say about the issues affecting young people today, and some ideas on how to solve our big problems. We’re going to hear from people about everything from housing affordability to LGBTIQ+ issues, feminism, drug legalisation, indigenous issues, mental health, decolonising space and much more.
This year we’ll be focusing on creating real solutions for real problems. These will be jumping-off points for different people from different backgrounds and industries to start conversations.
Because Junket is an “unconference”, there will be no set agenda or program decided in advance. It also means there will be no public audience.
As soon as we arrive in Canberra, our delegates will be encouraged to pitch a specific idea, problem or issue they want to talk about, and the types of people they need to make the conversation a good one.
The Junket program itself will be action-packed, with delegates choosing between up to ten different conversations happening simultaneously, throughout the day, with everyone encouraged to contribute to the conversation.
Junkee will have a team of writers, videographers and social media pros there to report on the conversations as they happen — and we’ve invited a few other media to cover proceedings too. This is just the beginning, though: the most important part of Junket happens in its aftermath.
Westpac, Qantas, Visit Canberra and the Australian Of The Year Awards are proud partners of Junket 2017, and are all pitching in with a little help to try to make some of our great ideas a reality.
In conjunction with The Cusp, Westpac will be hosting Stop, Collaborate & Listen, a skills exchange in which attendees will be given the opportunity to join forces with other Junket delegates and share their expertise to bring real-world solutions to life.
We’ll be hosting a meditation session thanks to the Qantas Dreamliner, as well as a secret session we’re not allowed to spill the details on just yet… but we can tell you it will be huge. Stay tuned.
If you want to get involved, jump on Twitter and check out the #Junket hashtag to contribute and keep the conversation going. The whole thing is happening in sunny Canberra from October 29 – 31. See you there! | <urn:uuid:a756971b-cef6-43fb-b118-5f7e35b0ce17> | CC-MAIN-2023-40 | https://junkee.com/junket-2017-attendees/130755 | 2023-09-26T05:04:13Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.927908 | 876 |
The price to earnings ratio (P/E) is an important tool in financial work. A random sample of 14 large U.S. banks (J. P. Morgan, Bank of America, and others) gave the following P/E ratios.†
24 16 22 14 12 13 17 22 15 19 23 13 11 18
The sample mean is x ≈ 17.1. Generally speaking, a low P/E ratio indicates a "value" or bargain stock. Suppose a recent copy of a magazine indicated that the P/E ratio of a certain stock index is μ = 18. Let x be a random variable representing the P/E ratio of all large U.S. bank stocks. We assume that x has a normal distribution and σ = 5.3. Do these data indicate that the P/E ratio of all U.S. bank stocks is less than 18? Use α = 0.05.
(a) What is the level of significance?
State the null and alternate hypotheses. Will you use a left-tailed, right-tailed, or two-tailed test?
H0: μ ≠ 18; H1: μ = 18; two-tailed
H0: μ = 18; H1: μ > 18; right-tailed
H0: μ = 18; H1: μ ≠ 18; two-tailed
H0: μ = 18; H1: μ < 18; left-tailed
(b) What sampling distribution will you use? Explain the rationale for your choice of sampling distribution.
The Student's t, since we assume that x has a normal distribution with known σ.
The Student's t, since n is large with unknown σ.
The standard normal, since we assume that x has a normal distribution with known σ.
The standard normal, since we assume that x has a normal distribution with unknown σ.
Compute the z value of the sample test statistic. (Round your answer to two decimal places.)
(c) Find (or estimate) the P-value. (Round your answer to four decimal places.)
Get Answers For Free
Most questions answered within 1 hours. | <urn:uuid:b9987b2a-246f-4a96-8fbf-b30529b02d7d> | CC-MAIN-2023-40 | https://justaaa.com/statistics-and-probability/160583-the-price-to-earnings-ratio-pe-is-an-important | 2023-09-26T06:30:26Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.92164 | 451 |
Chin up, chin up, everybody loves a happy face. Wear it, share it, it will brighten up the darkest place. Twinkle, sparkle, let a little sunshine in. You'll be on the right side, looking on the bright side...up with your chinny, chin, chin.
This quote from Charlotte's web appeared in my head when I saw this face.
Annie in deep thought.
There's the sweet face I love.
It's a real treat for me to see Addy in her window today as she is a hard one to find in the house when I cat-sit her. She's even hard to see in her window today. For a long time I referred to her as the phantom cat but it is a bit better now. At least I get to see the south end of her heading north most days.
This beauty was spotted while out walking Kane this week.
and this little one in amongst the tv cords.
I could not get his attention away from the dog.
I think I woke this fellow up.
We are still waiting on rain today. The gardens need watering and it will help green up the lawns.
Hope all is well where you are. | <urn:uuid:8b9566bb-5826-44af-927e-3db38dfabb28> | CC-MAIN-2023-40 | https://justcats-deb.blogspot.com/2014/05/chin-up-and-cats-in-windows.html | 2023-09-26T05:08:33Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.966635 | 259 |
Your Space To Create
With over 4,000 sq feet of space, Studio C is flexible in functionality. The 8’ clearance makes it ideal for tabletop or talking head shooting. It’s also the perfect private space for prep, (casting calls, wardrobe fittings, art department prep, overflow, lunchroom, and more.) Ready to take a look for yourself? Reach out at firstname.lastname@example.org to schedule a time to visit the space. | <urn:uuid:92ec2bd2-f5a0-4491-8b58-9bbff8a9e571> | CC-MAIN-2023-40 | https://k2studios.com/portfolio/studio-c/ | 2023-09-26T05:47:16Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.898207 | 98 |
Trade: Nigeria, UK host talks to boost £3.2bn partnership
Fred Omotara, Lagos
The UK and Nigeria held trade and investment talks today at the Economic and Development Forum (EDF) in London, to promote trade as a force for good and boost a partnership worth over £3 billion.
At the Forum held recently, both countries marked increased support for small and medium sized enterprises in Nigeria including the UK Manufacturing Africa programme, which has helped 12 firms in Nigeria secure foreign investment. When these deals conclude, they will generate over $300 million in foreign direct investment (FDI) for Nigeria and directly create 5,000 jobs.
The UK and Nigeria agreed to start discussions on an Enhanced Trade Partnership (ETP) to strengthen trade and high value investment across both countries.
An official working level group will be set up to explore the benefits of an ETP in priority sectors. DIT officials expect the increased ambition to build on long standing economic ties between the UK and Nigeria which is already worth £3.2 billion in 2021.
According to the UK Minister for Trade, Penny Mordaunt, “Nigeria is one of our long-standing and strategic partners in Africa, and I am pleased that the UK is continuing to deepen our investment relationship with one of the most vibrant and innovative economies in the continent.
“Through the Economic and Development Forum, we can demonstrate how trade is a force for good creating jobs and prosperity and reaffirm our commitment to boost economic ties, support businesses, and grow new markets.”
The Forum will include a tech matchmaking event for technology businesses from both nations hosted by venture capitalist firm LocalGlobe, in collaboration with TheCityUK, TechNation and Innovate UK tomorrow.
There, businesses will have the opportunity to explore potential partnerships and share best practice on how to raise vital development capital and registering a business in foreign markets.
In his own speech, Nigeria’s Minister for Industry, Trade and Investment, Otunba Niyi Adebayo stated that, “The Nigerian government is committed to implementing reforms that can attract more foreign direct investment into key industries, boost trade and development and create employment opportunities for Nigeria’s youth by leveraging technology.
“We welcome the commitment to enhancing the relationship between our two countries today and underscore the significance of deepening our bilateral trade policy relationship in a mutually beneficial manner.” | <urn:uuid:1a6f0158-a97d-4d75-a838-6404afe7c450> | CC-MAIN-2023-40 | https://kadecommunicationng.com/business-2/ | 2023-09-26T07:06:01Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.9362 | 498 |
Kaizen Foam FAQ (FREQUENTLY ASKED QUESTIONS)
What is Kaizen Foam?
Kaizen foam is a versatile and efficient organization tool that enables you to easily organize and protect your tools and sensitive equipment. This multi-layered foam product can be customized by tracing and cutting to create a snug fit for your items. Its design aims to improve productivity by helping companies establish organized systems and procedures with Kaizen foam. With Kaizen foam, you can bid goodbye to misplacing tools or equipment, saving you valuable time and effort.
What Type of Foam is Kaizen Foam?
Kaizen Foam is a high-quality Closed Cell laminated Polyethylene (EPE) foam that provides excellent shock absorption, vibration dampening, insulation, and buoyancy properties. This durable foam is well-suited for use in various products, where these properties are required, including packaging applications that require cushioning.
With a density of 0.0188 g/cm^3, Kaizen Foam is both strong and resilient. Additionally, it's not flammable, which makes it an ideal choice for applications where fire safety is a concern.
Overall, Kaizen Foam is a reliable and versatile foam material that can be used for a wide range of applications, thanks to its unique combination of properties.
How Do You Glue Kaizen Foam Together?
If you're wanting to glue Kaizen Foam inserts together, what has worked the best for us is using FastCaps 2P-10 Adhesive. Watch how it's done below:
How Do You Cut Kaizen Foam
Cutting Kaizen Foam is easier than you may think, and with a few simple steps, you can create custom-fit compartments for your tools or other equipment.
Step 1: Start by tracing the outline of your equipment using a Fastcap Kaizen Foam marker. Depending on how snug you want the fit to be, you can cut to the left or right of the outline.
Step 2: Use a thin-blade Kaizen knife or a sharp knife of your choice to cut out your outline, setting the blade to the desired depth.
Step 3: Peel away the layers of Kaizen Foam by sticking your fingers underneath the cutout and using them as a plow to peel away at your desired layer. You may also use a Kaizen Spinner to help cut off the inner foam.
Once you've completed these steps, check the fit by placing your gear back in the cutout and adjust as necessary.
For more tips and tricks on working with Kaizen Foam, check out this helpful video made by BrianWay.
In summary, cutting Kaizen Foam is a simple process that can help you achieve maximum organization and efficiency.
You can also purchase a Kaizen Tool Kit!
The Kaizen Knife Toolkit
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Great news for those who missed the deadline to file for portability: Uncle Sam is giving you a second chance.
Portability allows a surviving spouse to claim for his/her own estate any unused portion of the deceased spouse’s unified estate tax and gift tax exemption. Portability went into effect on January 1, 2011. Estate administrators have been required to file for portability within two years of the surviving spouse’s death, with a six-month extension available. Now, the IRS has extended the deadline: Effective July 8, survivors have five years from the date of the spouse’s death to claim portability. If your spouse has passed away on or since July 8, 2017, you may still file for portability.
Here is an overview of the portability provision and how it can allow a surviving spouse to save on federal estate taxes and pass on more tax-free money to heirs:
Current Unified Gift and Estate Tax Exemption
Currently, an individual may give away, during life and at death, a total of $12.06 million, free of gift tax and estate tax. For example, if Mr. Jones passes away this year and leaves an estate of $7 million, and leaves that to people other than his wife or to a credit shelter trust, he will not have used $5.06 million of his lifetime exemption ($12.06 million – $7.0 million). His widow, Mrs. Jones, can utilize portability to add his unused $5.06 million exemption to her own exemption (whatever exemption level is in effect for her at the time of her death). If he leaves it all to her rather than to anyone else, she will then have both his full exemption, as well as her own exemption is at the time of her death.
Gift and Estate Tax Exemption To Plummet in 2026
Effective January 1, 2026, the lifetime estate tax exemption will revert to its pre-2017 level, adjusted for inflation, reducing the amount of tax-free money that can be passed on. Experts guesstimate that the 2026 exemption will end up somewhere in the $6.2 million range. Here are examples of how this change in exemption level will affect a surviving spouse’s ability to pass on tax-free money to beneficiaries:
Example 1. Let’s say Mr. Jones has a gross estate of $3 million. When he dies, he leaves his wife $2 million and his children, $1 million. Any amount left to a spouse is not deducted from the decedent’s estate tax exemption. Therefore, Mr. Jones has used up $1 million of the $12.06 million exemption to which he was entitled, leaving $11.06 unused. Mrs. Jones, the survivor, may now file to have Mr. Jones’ unused exemption of $11.06 million added to whatever exemption the law gives her at the time of her death.
Example 2: Using the above example, let’s assume Mrs. Jones, the survivor, passes away in 2027, when the exemption has gone down to $6.2 million. Mrs. Jones leaves an estate of $15 million. An estate tax return is filed for her, showing she has her own exemption of $6.2 million, plus the unused exemption ported over from her husband’s estate, or $11.06 million, for a total of $17.08 million. Thus, she can pass her entire estate, $15 million, free of estate tax.
Now let’s say Mrs. Jones did not exercise her right to portability and thus is not entitled to any of her late spouse’s unused exemption. Her exemption at her death would be $6.2 million. The $8.8 million difference between the value of her estate and her exemption ($15 million minus $6.2 million) would be $8.8 million. That $8.8 million would be taxed at a rate of 40%, and Mrs. Jones’ estate would owe $3,872,000 in estate taxes (40% of $8.8 million).
Circumstances That Make Claiming Portability A Smart Move
Claiming portability is obviously wise when the surviving spouse has significant assets and it is likely that his/her own estate will be taxable upon death. But claiming portability can also be a smart move even for a surviving spouse with more modest assets. First, preserving the portability option is a safeguard against future reductions in the estate tax exemption that would make even smaller estates subject to federal estate tax (such as the dramatic reduction we expect in January 2026). Preserving portability is also worthwhile for younger couples, because there is the chance that the survivor could accumulate significant wealth in future years.
How To Claim Portability
To claim a deceased spouse’s exemption, the personal representative of the decedent’s estate must take the portability election on the estate tax return, IRS Form 706. To claim portability, the 706 must be filed even if the estate of the decedent is not subject to federal estate tax.
The time restrictions to file depend on the tax status of the decedent’s estate:
If the decedent’s estate is taxable: The estate tax return must be filed within nine months following the decedent’s date of death, or the last day of the extension period if an extension has been granted.
If the decedent’s estate is not taxable: Until now, the administrator of the estate had up to two years from the date of death to file the return and claim the portability option. However, the IRS has reported that numerous estates have missed the deadline because administrators did not realize they were required to file a return even for a non-taxable estate. The IRS has therefore issued IRS Revenue Procedure 2022-32 which gives estate administrators up to five years from the death of death to file the return and elect portability. This new rule went into effect on July 8, 2022.
A Huge Caveat!
If you are a surviving spouse and you remarry, you lose the right to your retain your prior spouse’s unused exemption – even if portability was properly filed for and preserved!
The Karp Law Firm Can Help Personal Representatives and Trustees
Our law firm’s estate administration department provides support and guidance for both personal representatives and trustees who are administering estates. Our attorneys can advise you about the possibility of claiming portability, and our Certified Public Account can handle completing and filing the required estate tax return. We can help you even if our firm did not create the original will or trust. If you need help, give us a call at (561) 625-1100 or email email@example.com. | <urn:uuid:8d2ce6af-3941-4266-a1cc-296a6f0884d6> | CC-MAIN-2023-40 | https://karplaw.com/great-news-for-those-who-missed-the-portability-filing-deadline/ | 2023-09-26T04:51:57Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.958898 | 1,410 |
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- Google the company and see if they’re in the news
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But you’re missing the most important step of all.
Before you do anything else, contact the HR/recruiter pro (or if it’s a small company, the hiring manager or admin) and ask some important questions that will help focus the rest of your pre-interview preparation.
Ask these questions:
- How much time should I plan on for the interview?
- Who will conduct the interview, names and titles? Once you have this info, go home and check interviewers’ LinkedIn profiles, so you know the basics about their experience and education
- If you are interviewing with multiple people, will the interview be a panel (all at one time) or consecutive interviews (30-60 minutes with each person individually) Bring a “Red Bull” if you’re being interviewed consecutively by several people. This can be very draining.
- Does the company have a proscribed style of interviewing (i.e. behavioral )
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- Is there anything you can tell me that will help me prepare for this interview? This might sound like you’re pushing it, but recruiters want you to do a good job. This makes them look good and that they’ve made a good choice. Hopefully the recruiter will share hot buttons of the interviewer.
Asking all of this intimidates a lot of candidates. Most often when they’re called for an interview, they get excited and schedule it and go in COLD…wrong. You can email these questions so the HR person can answer them during their own time. Or if even better, give him/her a call for a nice chat that starts by saying, “I’d really like to do well in this interview. Would you have a few minutes to answer a few questions that will help me to do my best?”
As a footnote to this… if you’re going for a government job, forget about asking these questions. The most you’ll probably get is the length of time of the interview and if it will be a panel or individual gig. | <urn:uuid:29ff5d20-1626-4a48-a15b-8109111c19b7> | CC-MAIN-2023-40 | https://kateculligan.com/before-your-interview-ask-these-7-questions/ | 2023-09-26T06:53:41Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.954361 | 625 |
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Throne and Liberty Boosting
Browse the websiteSTEP 1
Take a look at our wide selection of offers and choose the desired service from our store.
Consult with usSTEP 2
Share your thoughts with us, let us know what service would be needed and consult with our professional team.
Order the serviceSTEP 3
We are here to make sure its the right decision. Together we choose the best service for your character.
ALL SETSTEP 4
Once payment and final details are taken care of, a booster gets assigned and starts working on your order.
THRONE AND LIBERTY BOOSTING: WHY SHOULD YOU BUY?
Throne and Liberty Boosting is the process of getting a professional TL player on your account to help you effortlessly achieve any in-game goal and skip the grindy process of running the same content repeatedly.
At KBoosting, we have had vast experience with MMORPG boosting since the first days of World of Warcraft. We completed thousands of MMORPG boosting orders. We deliver TL boosting services like: leveling, gearing, builds, dungeon runs, items farming, PvP, and more.
Reasons to Buy Throne and Liberty Boost:
If you are wondering, "Why should you buy a TL boost?" below you can find a couple of reasons:
- • We have a vast MMORPG boosting experience starting from the early days of WoW.
- • Your safety & privacy are 100% guaranteed.
- • We calculate all prices based on the time & effort needed for the boost.
- • Our development team constantly updates all TL services to ensure you find everything you need.
- • We focus on quality, continuous improvement, and customer satisfaction.
- • We only work with verified Throne and Liberty boosters.
- • Our professional players signed a contract never to use hacks, mods, or cheats during a Throne and Liberty boost.
- • Managers are available 24/7 to check the progress of orders and intermediate the booster-customer relationship.
Our crew is ready to assign proficient players, eager to help you build a powerful character, reach the highest level lightning-fast, get your desired build, and fulfill tedious activities in the shortest time possible.
If you choose KBoosting, you don't have to worry about tracking your order. Our managers know that your time is valuable, so they supervise the booster's work 24/7. Our goal is to provide the Best Service for all our customers.
At KBoosting, you can find high-quality Throne and Liberty Boosting services and 24/7 support on our Live Chat and Discord to provide the smoothest gaming experience for all our customers.
THE BEST THRONE AND LIBERTY BOOSTING & CARRY SERVICES
From our experience in the MMORPG genre, we designed various TL Boost & Carry Services to cover any type of request, fitting our clients' preferences.
We deliver our Throne and Liberty services in two ways:
- • Piloted – (boosting) one of our professionals will use your account to complete the requested services.
- • Self-Play – (carry) you will play alongside our pro boosters.
If you choose Throne and Liberty Boosts, you share your credentials with our pro to complete any type of content without grinding yourself.
Choosing Throne & Liberty Carries, you will join our squad, learning new tricks while having fun.
TL Boost VS. Carries
Below, you can find a list of differences between Throne and Liberty Boosting & Carry:
- • Throne and Liberty Carries are the safest way to boost your account, but they take longer
- • Boosting has a faster delivery process, but requires account sharing
- • A TL boost doesn't require effort and saves you a lot of time
- • Carries are more satisfying for clients. You will learn the latest tactics from the best Throne and Liberty players
- • Go for a Throne and Liberty boost if you don't want to grind and just want to enjoy the rewards
- • Choose a TL Carry if you want to join a pro group capable of running any activity lightning-fast.
All our services are legit and 100% safe. Our experience in MMORPG games speaks for us. The boosters signed an agreement that guarantees that they won't use any hack when working on our customer's accounts.
You can contact us on our Live Chat or Discord for information or updates regarding your order.
If you are unsure what solution fits your needs, we can guide you, so don't hesitate to contact us.
Throne and Liberty Carry Services
Throne and Liberty carry is a service designed to help you team up with veteran players who can help you fulfill any activity regardless of difficulty. We can carry you through the campaign, Dungeons, and other activities in TL.
The term carry refers to a service completed in self-play mode, which means you don't have to share your login details as in piloted mode. You will control your character and join some of the most notorious Throne and Liberty boosters, learning new tactics while having fun.
Benefits of purchasing a Throne and Liberty carry:
- • When you go for a TL carry, you will learn the latest tactics from our pros.
- • You don't need to share your credentials
- • You will have fun playing with our professional teams
- • You will join a party capable of running any activity lightning-fast
- • In most cases, your gear may not be enough to defeat certain bosses solo, and you need a team that can keep up with you.
Our Best Throne and Liberty Carry Services:
Below, you can find a list of the most-wanted carries based on all the orders we've had so far:
- • Character Leveling
- • Campaign Completion
- • Items Farming
- • World Event Completion
- • World Boss Slaying
- • Profession Leveling
Our Throne and Liberty carry teams are ready to help you complete any challenging activity in no time. Choose our TL Carries for a better gaming experience.
Throne and Liberty Boost Pricing
We always keep Throne and Liberty prices updated and fair for our clients. Our services are not the cheapest option on the market, but they always reflect our high quality, the difficulty of the services, and the time needed for completion.
Safety should be your 1st concern when looking for a TL boost, so the lowest price will not always guarantee the best experience. We accept various payment options, so you don't need to worry about it.
How do you calculate the TL prices?
Many factors influence our Throne and Liberty pricing, such as:
- • RNG and the difficulty of the activity
- • The time needed to complete the service.
- • The number of boosters needed to fulfill the service.
- • Your current progress.
- • Delivery mode (self-played or piloted).
- • Delivery speed – normal or express (30% faster).
Our refund policy is settled to protect you from long delays and other inconveniences, so if we don't respect service requirements, you can always ask for a full refund. KBoosting 100% guarantees that you get the best value for your money.
We don't offer instant delivery services, because the activities require grind. All our services are completed manually by experienced boosters, and prices must reflect the time investment and task difficulty.
KBoosting is the best place to purchase reliable Throne and Liberty boosting. We provide high-quality services, focusing on customer safety and privacy. Our managers ensure that boosters follow all security requirements to provide the best boosting service.
Our Throne and Liberty Boosters
A Throne and Liberty Booster is an experienced gamer who has spent thousands of hours playing MMORPG games. All our players have been working with us since the beginning, and each booster has fulfilled many orders.
At KBoosting, we work with skilled gamers who can provide top-notch Throne and Liberty boosting services or share their experience with new players during TL carries.
How to become a Throne and Liberty booster?
In case you are wondering what conditions a booster must meet to be part of the KBoosting team, below you can find some of them:
- • Prove that he has vast experience in similar games & expertise as a boosting services provider
- • Have an impressive Throne and Liberty account with great gear, capable of running any activity fast
- • Be a dedicated gamer with a customer-oriented mindset and focus on continuously improving his skills.
- • Be part of a proficient team that can beat new content right after the release
- • Focus on customer safety & privacy
- • Attention to detail, being active daily, and providing updates for ongoing tasks
KBoosting managers always select the most suitable Throne and Liberty booster to work on your account, ensuring they do their best to deliver a high-quality boost, provide updates, and respect the ETA.
Is Throne and Liberty Boosting Safe?
We have completed thousands of orders in previous games and never faced any issues, so we can gladly claim that our services are legit and 100% safe.
Our boosters only complete boosts manually, and they are not allowed to use any hacks or cheats.
Can you get banned for Throne and Liberty Boosting Services?
The answer is NO. Your account is 100% safe when you choose KBoosting's services. Your account safety & privacy is our priority.
Usually, nobody gets banned for getting a Throne and Liberty boost, but if you choose the cheapest service on forums or obscure websites, the booster may use 3rd party software that will harm your account, ruin your progress, and get you banned.
By choosing KBoosting, you are 100% protected from incidents. We only work with pro verified players who are under a contract, and we regularly check them to ensure that all the work done on our customers' accounts is legit.
There is no risk involved when you decide to buy a Throne and Liberty Boosting service from our website. If you are still in doubt and wouldn't like to share your credentials, our Throne and Liberty Carry services are the safest option.
Our website chat is open 24/7, and support agents are ready to answer any question. After you place your order and payment is processed, they will assign a booster and keep you updated with the progress via email and Discord.
How do you Boost in Throne and Liberty?
We do our best to ensure that all Throne and Liberty boosting services offer our customers the smoothest and most exciting experience.
We made a little breakdown of the steps we follow when you purchase a boost in TL:
- 1. You decide what service fits your needs and place the order. You can use our help on Live Chat if you are not sure.
- 2. The payment is processed, and we receive the task.
- 3. The manager analyzes the request and starts looking for the best booster that will fit the order.
- 4. When the booster is assigned, you will be notified via email & notification. If needed, we can notify you via Discord too.
- 5. The manager intermediates the booster-customer relationship.
- 6. Our manager is responsible for scheduling the service and providing updates, especially if the boost takes more than one day.
- 7. If you go for a Carry, the manager will help you team up with our boosters, schedule the playtime, and ensure everything goes smoothly.
- 8. You can check the order status, progress & screenshots in your KBoosting Account -> Orders.
- 9. When the service is done, you receive an email and notification to log back in and enjoy the rewards.
The Throne and Liberty boosting process is straightforward and usually very easy for clients. Our team consists of professionals with a vast amount of experience in gaming and services.
TL Global Paid Services
When it comes to paid services, some variables can affect the process based on the customer's region, such as:
- • The drop and XP rates may differ and the service price may differ slightly.
- • ETA may be longer or shorter.
- • Booster's ping may be too high, making the assignment process complicated.
- • Timezone differences can affect the carries & maintenance schedule may vary.
Is Throne and Liberty region-locked?
Throne and Liberty has 7 regions: North America, South America, Europe, Australia, New Zealand, Japan, and Korea, allowing players worldwide to play. We have boosters available for every region mentioned above.
At KBoosting, managers know how to keep everything under control, the development team continuously updates our services and website features, and the boosters work with passion and dedication.
TL Carry services are schedule-dependent, so our managers must carefully handle these orders to ensure everything works smoothly for all clients. We work with boosters from all regions, so you are covered no matter where you are from.
Some Throne And Liberty boosting services can be time-dependant and require perfect timing, especially regarding time-gated activities.
If you need assistance, our customer service is available every day, 24/7, on live chat, discord or e-mail.
Frequently Asked Questions
What is Throne and Liberty Boosting?
What are the benefits of choosing Kboosting's Throne and Liberty Services ?
How are these services performed?
How long does the Throne & Liberty boosting service take?
When do you start working on my boost?
Is it safe to buy boosting services?
Do you have the best prices?
Do I get to control my account when i opt for a self-played boost?
7 YEARSof Experience
30 000+Boosts completed
We have been in the market for years. Our teams consist of veteran players ONLY, that are eager to help you out and take down any end-game challenge the game has to offer.
Blazing Fast Delivery
Your boost starts within 1 hour after order is placed and confirmed. Instant delivery on Email when purchasing one of our premade characters.
Our prices reflect that every service we provide is handmade, no shortcuts, exploits etc. We are not resellers, we purchase licenses and are original owners of any account we sell.
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If you’re looking for a comprehensive guide to LG texting, you’ve come to the right place. In this post, we’ll show you everything you need to know about using text messaging on your LG phone. We’ll cover how to send and receive texts, how to view/save messages, and how to use text features like chat heads and answer pending calls.
What does lg mean in text
LG is a brand that most people are familiar with, but what does it stand for? LG actually stands for “Lucky Goldstar.” The company was founded in South Korea in 1947 and started off as a producer of radios. Over the years, it has grown into a multinational conglomerate that manufactures a wide range of products, from appliances and electronics to vehicles and chemicals. In case you were wondering, the “G” in LG Electronics is derived from the company’s former name, Lucky Goldstar.
How to use LG in a sentence
LG is a popular Korean electronics brand that manufactures a wide range of products, from televisions and smartphones to home appliances. In this blog post, we’ll explore some of the ways you can use LG in everyday sentences.
If you’re looking for a versatile word that can be used in a variety of contexts, LG is the perfect candidate. Whether you’re talking about appliances or smartphones, LG is a brand that many people trust. As an English learner, it’s important to understand how to use this word correctly in order to make yourself understood by native speakers. Here are a few examples of how LG can be used in sentences.
Examples of how LG is used
There are many ways that LG can be used in everyday life. From cell phones to appliances, LG is a trusted brand that people rely on. Here are some examples of how LG is used in different ways.
LG phones are popular for their features and reliability. Many people choose LG cell phones because they offer a wide range of features, from cameras to Internet connectivity, as well as long-lasting battery power.
In addition to cell phones, LG produces a wide variety of appliances for the home. Its refrigerators, ovens, washers and dryers have been leaders in innovation and efficiency for many years. In fact, an LG refrigerator was named the best new product of the year by Appliance Magazine in 2010.
Pronunciation of LG
Lots of people have been asking how to say LG lately. Is it “Luh-Gee” or “Luh-Jee”? We’re here to help clear that up! In this post, we’ll share the proper pronunciation of LG and also explain some of its history.
Most people know that LG is usually pronounced as “L-G” but did you know there are other ways to pronounce it? In this blog post, we’ll discuss the different ways to say LG and when each pronunciation might be used. We’ll also provide some tips on how to correctly say LG in different situations.
As a writer, you must be familiar with the related terms of your topic. But do you know all of them? There are synonyms, antonyms, and definitions to learn. In order to have a well-rounded vocabulary for your writing, it’s important to understand the different types of words that exist.
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The Thames Valley Police Museum are holding open mornings on Wednesdays between 10.00am and 12.00pm.
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From finding an agent to closing and beyond, our goal is to help you feel confident that you’re making the best, and smartest, real estate deal possible. Some people use dating sites to scam other members out of their money. If you ever connect with a user who eventually asks you for money to support a family member or pay for a necessary expense, you can assume they’re lying to you. Some dating sites are pretty old and still have outdated interfaces. Others use interfaces that are too complicated for casual dating. When we reviewed the best dating websites to add to our list, we ensured that our top options have easy, straightforward navigation that even unsavvy computer users can operate. Elite Singles also offers an elite dating experience by removing inactive users from the site and providing relationship advice as needed.
These people are loses and te site is filled with girls saying there near you, but are really in Ghana. The pricing policy of the Fling portal is quite flexible. It is designed for long-term cooperation with users of the site. That is why there are several options for paid subscriptions. The longer you want to get a premium status on the site, the more profitable the offer looks. There is another exciting option, available only to premium users.
There are a lot of big companies in the market, but every man who’s going to enter the online dating scene should do careful research to find the platform that would work perfectly for him. When Xiao Li first saw Zhang Wei on a popular Chinese dating website, she knew she had found her perfect match. Zhang Wei was everything she had ever wanted in a partner – he was handsome, intelligent, and funny. After messaging back-and-forth for a few weeks, they finally met in person. They quickly began dating and within months, they were talking about getting married. Now, Xiao Li and Zhang Wei are one of the happiest couples around. They credit their success to the fact that they found each other through online dating – something that may not have been possible without modern technology.
A breakdown of individual numbers
The price of reaching a potential match depends on the internet dating site. Singles50 touts its data-driven approach when it comes to coordinating singles. After signing up, new members complete a personality assessment honestly, that is used to give you an idea about14964 potential fits. Zoosk is a popular online dating site that has been in business for over 13 years. While the average age range of users on this site is between 24 and 27, you’ll find many older adults in the dating pool. The site has had over 35 million members in its life span. However, some dating sites offer better experiences for mature singles than others. We’ve reviewed the best senior dating sites for singles over 40.
Each of our ultimate best 3 get together sites
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They will not be the type who go out nightclubbing every night or stay home watching TV on the couch. There are always seminars being offered at your local hotels for all types of professional occupations. This would be my number one place to seek out a partner in life who has ambition and an interest in long term relationships. Most, if not all the women who attend nonprofit galas are very well-educated, very career driven and very high quality relationship oriented women. The women at each of these venues listed below will be educated, motivated and seeking a high quality man like yourself.
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India will begin its Test campaign against West Indies on July 12 in Dominica, followed by three ODIs and five T20Is in a multi-format series.
West Indies ’ performance tutor Brian Lara believes his players are moving in the “ right direction ” and hoped some of them will snare the occasion and produce the goods against a redoubtable India in the forthcoming two- Test series.
India will begin its Test crusade on July 12 in Dominica, followed by three ODIs and five T20Is in a multi-format series.
“We’ve two veritably important Test matches which start the two- time cycle (World Test Championship) for us, it’s against India. At home and down from home, they’re one of the top brigades in the world, ” said Lara.
“I suppose the guys are moving in the right direction, in terms of where we started the camp and where we are. It’s just a many days out from the first match at Dominica, but it’s a youthful group, adeptly lead by Kraigg Brathwaite. But I feel that some of the guys can come into their own in this series, it’s a tough opposition but I feel that’s the way we can get the stylish out of them, ” he added.
The 53- time-old fur great, who was the head trainer of Sunrisers Hyderabad during the IPL (Indian Premier League) this time, said the two youths have the right station and amenability to learn and can make it big in transnational justice.
“Great able players, youthful and of course, you would have loved if they had a lot further experience in the First- Class arena but looking at their style of play and station, I belief they do have what it takes to perform at the loftiest position, ” he said.
“It may take some time but obviously as an transnational cricketer if you’re entering this stage, no matter what age you enter, you got to learn veritably, veritably snappily. And, I suppose they’ve that kind of station to want to learn and( are) willing to hear. ”
West Indies finished at the eighth spot with just four triumphs and seven losses in the last WTC cycle.
The Caribbean platoon has failed to qualify for the forthcoming 50- over World Cup in India. Know More Latest Cricket News… | <urn:uuid:f10816ef-b99b-4ea8-8356-ecd2c0b06081> | CC-MAIN-2023-40 | https://key11.news/wi-vs-ind-brian-lara-expects-west-indies-players-to-come-good-against-india/ | 2023-09-26T06:56:05Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.959714 | 521 |
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Keystone’s impact planning, assessment and learning systems build on the strengths of traditional M&E and address some of their frustrations:
- they recognise that social change processes are complex and non-linear: planning is focused on who has to do what for success,
- they help develop realistic and effective strategies,
- they provide a rigorous monitoring framework geared towards continuous learning, adaptation and improvement,
- they focus on hearing the voices of all the constituents of social change and on strengthening dialogue,
- they generate summary, quantified data for senior managers, which can be compared and aggregated.
Nelson Mandela Children’s
The process of designing an impact planning, assessment and learning system usually involves:
- workshop(s) for clarifying the organisation’s or programme’s Theory of Change
- identifying strategies and specific indicators, and developing templates for data collection and storage
- monitoring indicators, using a variety of methods, including gathering feedback from constituents
- reporting progress back to constituents and also publicly (as appropriate)
- structured opportunities for reflection to review progress and the Theory of Change and make plans for the future.
Read some short examples.
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Today Sehri & Iftar Time Bhayandar 2023
26 Sep, 2023
10 Rabi ul Awal 1445, Sehri and Iftar time in
are as Fiqa Hanafi Sehri Time is
05:14 AM and fiqa Hanafi Iftar Time is
6:34 PM. According to Fiqa Jafria Sehri & Iftari timings are as follows: Shia sehri time in
and Iftar time is
06:44. The Ramadan time table 2023 is given below.
Sehr o Iftar Time Bhayandar
Today 25 September 2023 Sehri time Bhayandar is 05:14 am and Iftar time Bhayandar is 6:34 pm in Fiqa Hanafi.
Ramadan arrives and Muslims across the world dedicate their time and energy in fasting and praying to seek forgiveness from Allah Almighty. The exact
Ramadan Timing 2023 on
25 September 2023
10 Rabi ul Awal 1445
has given on this page along with Sehri time in
and Iftar time today
Sehri time in
during Ramadan 2023 is estimated to be around
and Iftar time is estimated to be around
6:34 pm. These timings are based on the calculation method used by the Fiqa Hanafi, which is followed by the majority of Sunni Muslims in
For the Fiqa Jafria, the estimated Sehri time in
during Ramadan 2023 is around
AM and the estimated Iftar time is around
PM. This calculation method is followed by the majority of Shia Muslims in
The Ramadan timetable 2023 in
is an important event for the Muslim community and accurate information about the Sehri and Iftar timings is crucial for those observing the fast. The estimated timings mentioned above are based on the calculation methods used by Fiqa Hanafi and Fiqa Jafria and may vary slightly depending on the sighting of the moon and other factors.
What is the Sehri time in
Many people use the Ramadan calendar 2023
to check suhoor or Sehri time in
Bhayandar. Today's Sehri time is
25 September 2023, and the fasting day is expected to last
13 hours 20 minutes.
What is the Timing of Iftar in
The overall length of each fasting day determines the distance between Roza or Iftar hour. Today's Iftar time in
25 September 2023, and tomorrow's iftar time is
What is the exact starting time of Iftari in
The exact starting time of Iftari in
Typically, Iftari time is at sunset.
What is the end time for sehri in
The end time for Sehri in
depend on day to day solar movement. Typically, Sehri ends approximately 5-10 minutes before the Fajr prayer time.
What time did Roza close in
The exact time when Roza closes in | <urn:uuid:d4dc4c25-b7fb-4639-a4db-61d84941781d> | CC-MAIN-2023-40 | https://kfoods.com/ramadan-calendar-timings/bhayandar-seher-iftar-timing_108084 | 2023-09-26T05:39:10Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.876384 | 831 |
Sweetwater, Texas facts for kids
Quick facts for kids
Municipal building north of the Nolan County Courthouse.
"Life Is Sweet In Texas"
Location of Sweetwater
|• Total||11.07 sq mi (28.68 km2)|
|• Land||11.07 sq mi (28.68 km2)|
|• Water||0.00 sq mi (0.00 km2)|
|Elevation||2,169 ft (661 m)|
| • Estimate
|• Density||945.37/sq mi (365.01/km2)|
|Time zone||UTC-6 (CST)|
|• Summer (DST)||UTC-5 (CDT)|
Sweetwater is a municipality in and the seat of Nolan County, Texas, United States. It is 123 miles southeast of Lubbock and 40 miles west of Abilene, Texas. Its population was 10,906 at the 2010 census.
Sweetwater received a U.S. post office in 1879. The Texas and Pacific Railway started service in 1881, with the first train arriving on March 12 of that year, beginning Sweetwater's long history as a railroad town. To encourage the railroads, Sweetwater increased its water supply by building a small town lake in 1898, and three larger lakes thereafter. Construction began on the Kansas City, Mexico and Orient Railway in 1903. Sweetwater became a railroad town, with businesses and homes built along the rail line. Rail passenger service was discontinued in 1969.
Gulf Refinery operated there from 1929 to 1954, and at one time the town was a large telegraph center. The International Harvester Company operated a factory in Sweetwater from 1920 to 1950. Gypsum plants, apparel manufacturers, cement plants, cotton compresses, a cottonseed oil mill, and packing companies were among the nearly 250 businesses operating there from the 1970s. Many still operate today. Sweetwater remains a production hub for cotton, oil, and cattle. The population of Sweetwater has remained steady between 11,000 and 13,000 since 1940.
At Sweetwater during World War II, the Women Airforce Service Pilots (WASPs) were trained under the direction of the famed aviator Jacqueline Cochran at Sweetwater's Avenger Field. These WASPs were the first women to fly American military aircraft. The military airstrip closed abruptly at the end of the war, but pilots flying over Sweetwater can still land at Avenger Field – the Sweetwater Airport (SWW). The National WASP WWII Museum is located at Avenger Field. The WASP women were not recognized for having served in the armed forces until 1977, when U.S. Senator Barry M. Goldwater of Arizona and Colonel Bruce Arnold, late son of General Hap Arnold, persisted in obtaining their official recognition as military veterans. In 1970, the field became the site of Texas State Technical College in Sweetwater.
Sweetwater also has a Pioneer Museum, with display rooms depicting the lives of early settlers with extensive photograph files, farm and ranch exhibits, Indian artifacts, and WASP exhibits.
Sweetwater has a hospital (founded 1976), an 18-hole golf course (opened 1958), a local newspaper (founded 1881), a municipal auditorium (where Elvis Presley once performed), a historic renovated movie theater, and a large public swimming pool, as well as public fishing and recreational facilities at Lake Sweetwater.
One of the earliest congregations that continues to exist in Sweetwater is First Baptist Church.
Parts of the south side of Sweetwater were devastated by an estimated EF3 tornado that swept through town early in the morning of April 19, 1986.
Sweetwater is the center of the Western Hemisphere's leading wind power generation region. It is sometimes incorrectly called the "Wind Turbine Capital of Texas", as the largest wind farm in Texas is the Roscoe Wind Farm. which does not regulate wind power. About 1,330 direct wind-related jobs were created in Nolan County alone (in 2009), with almost $18,000,000 in annual landowner royalties and over $12,000,000 in annual local school taxes (2007).
The world's largest rattlesnake Round-Up has been held annually by the Sweetwater Jaycees on the second weekend in March since 1958, along with the Gun and Coin Show hosted by the Sweetwater Rifle and Pistol Club which was founded in the 1940s.
According to Tom Henderson, a member of the Sweetwater Chamber of Commerce Board of Directors:
"If you're bored here, it's your own fault."
Sweetwater is located at(32.468147, -100.407125).
According to the United States Census Bureau, the city has a total area of 10.0 square miles (26 km2), all of it land.
Sweetwater is the center of the Western Hemisphere's leading wind power generation region and West Texas has more than 4,000 MW of operational wind energy. Nolan County alone would currently rank as the eighth largest "nation" in terms of wind energy generation - with more than 1,500 MW installed.
Climate type occurs primarily on the periphery of the true deserts in low-latitude semiarid steppe regions. The Köppen climate classification subtype for this climate is BSk (tropical and subtropical steppe climate).
|U.S. Decennial Census|
As of the census of 2000, 11,415 people, 4,545 households, and 3,017 families resided in the city. The population density was 1,139.4 people/sq mi (439.9/km2). The 5,202 housing units averaged 319.2/sq mi (200.4/km2). The racial makeup of the city was 75.29% White, 5.83% African American, 0.58% Native American, 0.32% Asian, 0.07% Pacific Islander, 15.71% from other races, and 2.21% from two or more races. Hispanics or Latinos of any race were 31.70% of the population.
In the city, the population was distributed as 28.1% under the age of 18, 8.9% from 18 to 24, 26.0% from 25 to 44, 21.1% from 45 to 64, and 15.8% who were 65 years of age or older. The median age was 36 years. For every 100 females, there were 91.1 males. For every 100 females age 18 and over, there were 86.7 males.
The median income for a household in the city was $24,293, and for a family was $29,953. Males had a median income of $27,722 versus $18,064 for females. The per capita income for the city was $13,065. About 20.5% of families and 23.7% of the population were below the poverty line, including 31.5% of those under age 18 and 22.0% of those age 65 or over.
In popular culture
In King of the Pecos, a 1936 film starring John Wayne, Muriel Evans, and Cy Kendall, Sweetwater is portrayed as a single homestead and said to be a necessary watering stop for the first cattle drive presumably up what would become the Pecos Trail towards Abilene, where a new railhead has been completed. Pecos to Abilene is about 250 miles, but said to be 1600 miles by characters in the movie, though they cross the distance with cattle in a short time.
"Sweetwater, Texas" is the last song on the 1976 Charlie Daniels Band album Saddle Tramp.
"Sweetwater, Texas" is the title of the sixth episode of the CBS Western television series Trackdown, starring Robert Culp as Texas Ranger Hoby Gilman. The episode aired on November 8, 1957. In the story line, Gilman finds an abandoned baby in a stagecoach which has been robbed, and all other passengers were killed. His clue is the photograph of a woman, presumably the mother of the child. Paul Richards and Ray Danton guest star.
On the album All the Pain Money Can Buy by Fastball, "Sweetwater, Texas" is name of the last song.
Sweetwater is the namesake for the town in the film 1968 Sergio Leone spaghetti western Once Upon a Time in the West. The town was a location in an episode of the American television show Maverick . Willie Nelson's film, Red Headed Stranger, was made in Sweetwater.
In Rodgers and Hammerstein's musical Oklahoma!, Jud Fry refers to an act of arson that takes place in Sweetwater.
In J.K. Rowling's book Quidditch Through the Ages, one of the United States teams mentioned is the Sweetwater All-Stars.
The City of Sweetwater is served by the Sweetwater Independent School District, which includes J.P.Cowen Early Childhood Center, East Ridge Elementary, Southeast Elementary, Sweetwater Intermediate School, Sweetwater Middle School, and Sweetwater High School. For more information about Sweetwater ISD, visit the official SISD website: http://sweetwaterisd.net/.
Sweetwater is the home of the West Texas campus of the Texas State Technical College System, which added the first community college wind-energy program in Texas in 2007. Also in 2007, TSTC constructed a demonstration 2 MW 60 Hz DeWind D8.2 prototype wind turbine for student training.
- Joe Banyard, former NFL player for the Jacksonville Jaguars, New Orleans Saints, Minnesota Vikings, and Buffalo Bills
- Sammy Baugh, Hall of Fame NFL and TCU football player, was born in Temple. He went to school at Newman High School and played for the Sweetwater Mustang football team
- Doyle Brunson, the poker legend called "Texas Dolly"
- Frank Hamer, a Texas Ranger who along with his brother Gus had a pistol fight on October 1, 1917, in Sweetwater with Gee McMeans, in which the former Ranger and sheriff of Ector County, Texas, was killed
- John Layfield, retired professional wrestler, is best known for wrestling as "Bradshaw" or "JBL" with the WWE. Layfield was a guest panelist on Fox News Channel's The Cost of Freedom, and is also employed by Northeast Securities as its senior vice president
- Blackjack Mulligan, retired professional wrestler, was best known for his work in the American Wrestling Association and the National Wrestling Alliance
- Jack Roberts (1910-1988) was a United States federal judge of U.S. District Court for the Western District of Texas
- Tex Robertson, University of Texas swimming coach, was born in Sweetwater
- Zollie Coffer Steakley, Jr., Texas Secretary of State and Texas Supreme Court, practiced law in Sweetwater during the 1930s
- Clyde Bulldog Turner, a graduate of Sweetwater High School, is a member of the Pro Football Hall of Fame
- Bobby Witcher, an amateur herpetologist best known for his charismatic personality and carefree handling of venomous snakes, was born in Sweetwater in 1916
Images for kids
In Spanish: Sweetwater (Texas) para niños
Sweetwater, Texas Facts for Kids. Kiddle Encyclopedia. | <urn:uuid:3a13faa6-692d-4195-bcfc-b3496927f2fe> | CC-MAIN-2023-40 | https://kids.kiddle.co/Sweetwater,_Texas | 2023-09-26T04:56:32Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.955001 | 2,714 |
You will love this super soft and flirty retro pornstar short sleeve t-shirt. It has a fun retro vibe and is the kind of t-shirt you’ll want to wear all the time.
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NO RETURNS unless there’s a defect. | <urn:uuid:9b3504b5-fc7b-488e-b8a1-0595cb53a80f> | CC-MAIN-2023-40 | https://kinkyinkpress.com/product/retro-pornstar-short-sleeve-t-shirt/ | 2023-09-26T05:24:22Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.878577 | 104 |
Annyeonghaseyo! (안녕하세요) 안녕하세요) That means “hello” in Korean. Yeah, I know I’ve been hit with the Korean fever, but hey, you should admit that Korean food is really good, right? Remember I made some tteokbokki, which is a delicious Korean street food? Now, I have also started making kimchi instead of buying at the store. The process is a bit tedious because it takes time and effort but totally worth it. I can also customize the kimchi according to my liking — if I want it sweeter, with more garlic, etc.
What’s so Great About this Korean Food?
Since I love spicy food, I am automatically attracted to Korean food due to its spiciness. I also noticed that the spiciness of the ingredients don’t leave a burning taste. The Korean pepper flakes that I bought also smelled a bit sweet and musky. I decided to make my own kimchi so I can store it and it’s ready to eat anytime! I even gave some to my sister and my friends — maybe I should sell them, too, don’t you think?
Anyway, I research different ways of preparing kimchi. Another thing that I noticed about Korean food, specifically kimchi, is how they prepare it. It’s a long process, with the salting and washing of the vegetables, and one wrong step will ruin it. The traditional way of making kimchi is different from the newer methods. For example, the traditional way of making kimchi requires whole napa cabbage leaves instead of chopping them into bite size pieces. Also, they have this special Korean earthenware called the “onggi” to store the kimchi. I also saw a video where they dry the washed napa cabbage leaves in bamboo slats. Not sure if that adds flavor but it looks cool.
Let’s Make Homemade Kimchi!
Let’s get started! Make sure you have lots of rock salt, a large basin, and a large coriander. You can even use the cooling racks to dry the washed napa cabbage with. Make sure your hands are clean and dry, too. Have some plastic gloves ready to mix the kimchi with, because the red paste may sting and make your hands red.
Please share this recipe with your Korean fanatic friends, too! Don’t forget to leave us a comment and share your kimchi-making experience!
Easy Homemade Kimchi
- 1 large Napa cabbage
- 1 cup rock salt not iodized
- 1 large carrot julienned
- 1 radish cut into cubes
For the Kimchi Paste:
- 1 tsp minced ginger
- 1 tbsp onion chopped
- 1 tbsp garlic minced
- 2 tbsp fish sauce
- 5 tbsp Korean red pepper flakes
- 1-2 tsp sugar
- 2 cups water
- 2 tbsp Glutinous rice flour
- Cut off the hard part of the Napa cabbage.
- Separate the leaves and cut them into 1 inch slices.
- In a large baking pan, put the cut-up leaves and sprinkle generously with salt, making sure to coat all leaves. Toss the leaves with your hands to evenly distribute the salt. Leave it for 30 minutes to allow the moisture to come out, tossing every 10 minutes to distribute the salt.
- To check if the Napa cabbage is ready, get the hard white part and pinch it between your fingers. If it seems soft and does not break right away, then it is ready.
- While waiting for the Napa cabbage, mix the water with the glutinous flour. Mix it for 5 minutes until it turns into a paste. Turn off heat and set aside to cool.
- Once the paste cools, proceed to making the kimchi paste. Mix the red pepper flakes, sugar, and fish sauce along with the flour mixture. Mix well to combine then add the carrots and radish. Set aside.
- Wash the salted Napa cabbage 3-4 times to remove the saltiness. On the last rinse, squeeze out the excess water. Let them dry on a cooling rack placed on top of a baking pan for about 30 minutes.
- When the Napa cabbage is a bit dry, mix it with the paste. Use plastic gloves to cover your hands and mix well, making sure to coat every piece with the paste.
- Prepare clean jars with covers. Carefully spoon the kimchi into each jar. Make sure to press down on the kimchi as you spoon them to remove air bubbles. Leave about half an inch of space from the lid. Press firmly on top of the bottle to release air bubbles then cover. You may need to check back after and hour and press down to remove any air bubbles that may have formed.
- Store in room temperature for a day then refrigerate after. It will continue to ferment in the fridge. If the weather is hot, keep it at room temperature for half a day only then refrigerate afterwards. When the kimchi turns a bit sour, it means it has fermented. | <urn:uuid:523831b0-1e97-40e1-aa10-fc30c17874f1> | CC-MAIN-2023-40 | https://kitchenatics.com/recipes/korean-food-easy-homemade-kimchi/ | 2023-09-26T05:56:13Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.921452 | 1,114 |
Klinedinst understands that eDiscovery can prove to be a vital part of successfully litigating a case and therefore requires careful planning, oversight and execution.
Our eDiscovery team has decades of experience working on cases ranging from those involving a few thousand documents to complex class-actions and government investigations involving millions of documents. Recognizing that eDiscovery can be costly, the team believes in collaborating closely with clients, including when pre-planning and budgeting.
Areas of service include:
- Preservation, including legal holds and third-party preservation letters
- Identification of relevant data
- Early Case Assessment
- Defensible document collection
- Drafting and negotiating of ESI protocols
- Meet and confer / pre-trial conferences on eDiscovery issues
- eDiscovery briefing and motion practice
- eDiscovery vendor selection
- Search methodology and data analytics
- Processing and hosting of data
- Document Review and analysis | <urn:uuid:63a67200-26f1-4fec-bf98-64513b960aa2> | CC-MAIN-2023-40 | https://klinedinstlaw.com/practice/ediscovery | 2023-09-26T06:39:40Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.903304 | 192 |
James J. Reynolds is an AV® Preeminent™ rated Senior Counsel in the firm’s San Diego office. Mr. Reynolds has represented clients in a variety of disputed matters for over 35 years. He has significant experience with jury trials, administrative hearings, arbitrations and appeals, and he routinely provides pre-litigation advice and guidance on contract preparation, insurance coverage and risk avoidance.
Mr. Reynolds extensive and broad litigation/dispute resolution experience includes breach of contract; shareholder disputes; trade secrets, employee confidentially and non-disclosure agreements; and patent and trademark prosecution and defense. He represented a Cayman Islands company in a lengthy, complex shareholder lawsuit concerning carbon trading under the Kyoto Protocol with alleged damages exceeding $150 million. Mr. Reynolds successfully defended the monetary claim and obtained over $6 million for his client on a cross-complaint.
Within his practice, Mr. Reynolds has extensive experience with Errors and Omissions, Comprehensive General Liability and Directors and Officers insurance coverage issues, ensuring clients receive the best representation possible while obtaining the benefit of any potential insurance protection and coverage. He has represented numerous real estate owners, general contractors, design/engineering professionals and subcontractors in litigated matters including contract disputes, liens and construction defect claims.
Mr. Reynolds is a member of the American Board of Trial Advocates, a prestigious organization comprising only the most experienced trial attorneys in the United States. He has maintained an AV® Preeminent™ rating with Martindale Hubble since 1987, is a panel arbitrator for the American Arbitration Association, serves as pro tem judge for the San Diego County Superior Court and was selected one of “San Diego’s Top Lawyers” by San Diego Magazine in 2015.
Mr. Reynolds maintains an active Alternative Dispute Resolution practice serving as arbitrator and mediator for the American Arbitration Association and the San Diego County Superior Courts. His ADR experience reaches back to the early 1990s when he acted as an arbitrator for the San Diego County Superior Court and was one of the initial members of the Court’s approved mediator list. In 2002 Mr. Reynolds was appointed to the American Arbitration Association’s commercial dispute arbitration panel. He also has served as judge pro tem for the San Diego County Traffic Court and Small Claims Court programs. For many years Mr. Reynolds volunteered his services as a San Diego County Bar Association’s Fee Dispute arbitrator, resolving fee disputes between a client and their lawyer. He also was a volunteer attorney for the SDCBA’s Immigration Services program and successfully advocated for permanent asylum for several immigrant families. He is still active in the legal community, and is an member of the State Bar of California. | <urn:uuid:8f200983-ecf2-45de-999b-7291c28ccb43> | CC-MAIN-2023-40 | https://klinedinstlaw.com/profiles/attorney/james-reynolds | 2023-09-26T06:22:40Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.961715 | 554 |
Stuff You Didn’t Know About “Turkey Day,” Part One
Thanksgiving is one of those days we all celebrate, but know very little of the history, or events associated with it. From Pilgrim times to 2012, Thanksgiving traditions continue to evolve. Turkey, dressing, green bean casserole, cranberry sauce, pumpkin pie, football, parades, and booze all make this one of the boons to our somewhat anemic economy. Will this holiday season pull companies out of the red? I guess we’ll find out soon.
The First Thanksgiving
No one knows for sure what the menu was at the first Thanksgiving but historians tend to agree on one common fact. No turkey was served. Seafood and venison were the bill of fare for that history-changing event.
Then how did turkeys become the meat of choice for future feasts? Wild turkeys were very plentiful, you could feed a lot of people with a single bird, and Tom Turkeys didn’t lay eggs so they were an easy choice.
If You’re Thankful For Thanksgiving — Thank Lincoln.
Some presidents celebrated Thanksgiving and some didn’t. Among those who did not was Thomas Jefferson. James Madison did a couple of times but not always in the fall of the year. You can thank our 16th President, Abraham Lincoln for creating the holiday and federalization of it in 1863. Perhaps he was thankful the Civil War would only last another two years.
What would Thanksgiving Be Without Macy?
What would Thanksgiving be without the movie, “Miracle on 34th Street” and the Macy’s Thanksgiving Day Parade. The parade started in 1924 and instead of the inflatable floats, Macy got live animals from the Bronx Zoo to march in the parade. “Felix The Cat” was the first inflatable balloon provided by the Goodyear corporation in 1927. Mickey Mouse joined the fun in 1934.
I’m Older Than Green Bean Casserole
Not sure how I feel about that. Most people reading this grew up with this holiday staple. Fifty-three year old green bean casserole is a real marketing phenomenon. Campbell’s soup was looking for creative recipes to improve the sale of their soups, — particularly mushroom soup. So take a vegetable that no one likes and combine it with several unhealthy other items and wha-la, a tradition is born.
The day before Thanksgiving is the biggest day of the year for bar sales. Bigger than New Years Eve, the Super Bowl, and St. Patrick’s Day. Why you ask? Contrary to popular belief, you can go home again. And millions of people do — they meet up with friends and family and hit the bars. I think it’s because mom wants everyone out of the house so she can cook and get organized. Plus you are going to have the pain of spending the following day with family and drinking may be your only defense.
Some Final Thoughts
Tomorrow I’ll have a few more tidbits of things you might not know about Thanksgiving. Why does Detroit always play football on Thanksgiving? Is Cyber Monday for real? And when did Pumpkin Pie enter the picture? In the meantime it’s your last chance to hit the store and make sure you’ve got all the fixin’s for the big day. | <urn:uuid:8429ab0d-2b2c-4094-a4f0-beaead0915fa> | CC-MAIN-2023-40 | https://kmmsam.com/stuff-you-didnt-know-about-turkey-day-part-one/ | 2023-09-26T05:33:33Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.954369 | 700 |
Both authors of How to Make the Rest of Your Life the Best of Your Life are wise, experienced, and have used their own advice with admirable results. Mark Victor Hansen is the co-creator of the Chicken Soup for the Soul series of books and is a very popular public speaker. Art Linkletter is the TV host and author of Kids Say the Darndest Things. He is a highly regarded speaker and advice giver. Both men have inspired many with their well regarded writings and wise advice.
How to Make the Rest of Your Life the Best of Your Life is divided into two parts. The first part of the book presents examples and dispels myths about how an older person can be vital, active, healthy, and full of purpose. As the authors say, “it can be an incredible time of freedom and discovery and learning and purpose.” They assert that “The 60’s are the new 40’s and the 80’s are the new 60’s.” The second and longer part of the book is specific and in-depth about eight aspects of the life of the older person. This part of the book gives new and surprising information about health, money, sex, creativity, attitude, spirituality, and the active mind.
The goal of the book’s two parts is to help the reader to embrace the Ten Empowerments, as outlined in the book’s Introduction. With these empowerments, the reader will be ready to purposely live the second set of the prime years of their life.
The book is full of fun and enlightening features that make it easy to read. For example, the authors are good at creating meaningful lists. In the first few pages of the book the authors present one of the book’s underlying themes, The Ten Empowerments. These empowerments are reflected in the chapters of Part II where eight of the empowerments are talked about in great detail. The next list is given in the book’s first chapter where the authors discuss the Eight Great Myths About Growing Old. They, of course, skillfully knock down the myths that they identify. Then, throughout the book’s Part II the reader will find 11 Agelessness Secrets. The Agelessness Secrets are fun to read because they are remarkably simple and of an everyday nature. Here’s one of my favorites: Do the Crossword Puzzle. I shook my head in surprise at first but it made sense when I read the explanation for it.
A couple of other attractive features of the book are the way the authors use quotes and humorous stories. Each chapter begins with a couple of quotes that are appropriate to the topic of the chapter. The quotes are often inspirational or funny and always worth reading. The humorous stories are easily identified by the grey background color. Some of the stories are true, some are anecdotes, and some are old jokes that are worth hearing again. Either way, the stories are fun.
Another great feature of the book is the way the chapters are summarized at the end of each chapter. The authors include exercises and lists designed to help the reader put into action what they have learned in the chapter. The lists also serve as a helpful summary of the chapter.
Lastly, a feature that I greatly appreciated was a long listing at the end of the book of resources appropriate to each of the Empowerments that are discussed in the book. The resources include websites, magazines, and books, many of which were mentioned earlier in the text of the chapters. The resource list is there to supplement the memory of the reader who may have forgotten to write down an idea or a resource that they ran across earlier in the book.
Hansen and Linkletter have done an inspired job of writing a book that all older adults should read. The result will be a better and fuller life. As the authors say in the closing of the book, “That is the vision we have for you: of a life that’s rich and crazy and audacious and passionate and brilliant and giving.” | <urn:uuid:42618db7-73d1-4d30-97a7-d3dc89143f68> | CC-MAIN-2023-40 | https://kmsciences.com/how-to-make-the-rest-of-your-life-the-best-of-your-life-book-review.html | 2023-09-26T04:54:19Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.956316 | 831 |
International Partners to Liberia Writes Pres. Weah on Holding 2022 Census
Several International Partners have written President George Manneh Weah on holding the 2022 National Housing and Population Census planned by the Liberia Institute of Statistics & Geo-Information Services (LISGIS).
They believe Liberia’s fifth census since 1964 and the first digital census must be held in October to provide important information for development planning.
On behalf of the partners, which include ECOWAS and the United Nations, UN Resident Coordinator Niels Scott outlined gains made by the steering committee despite significant delays caused by Covid-19 and other unforeseen reasons.
The partners have presented a vote of confidence on LISGIS’ ability and technical knowhow to conduct the census.
“Logistical equipment and supplies have been procured and enumeration staff are in place. Substantial financial resources to conduct the census are available,” said Scott in a 25 July letter co-signed by Finance & Development Planning Minister Samuel D. Tweah, Jr., who chairs LISGIS board.
“LISGIS have completed the geographical mapping and a pilot census (pre-test census), which has informed the preparation for the actual census. 21,000 tablets and 21,000 power banks have been secured from Ghana through a south-south cooperation with Liberia.”
The Senate, after a lengthy plenary discussion on 16 June, moved the census to March 18-30, 2023 pending a concurrence by the House of Representatives although LISGIS had proposed 16-28 October.
The partners have advised President Weah about the financial implications and ramifications of that decision based on a steering committee meeting held on 4 July.
If the census is postponed to March, they argued, the obligatory payments to census staff will be US$695,500, which will significantly reduce to US$139,100 if the census is conducted in November and US$278,200 if it is conducted in December.
The postponement will also affect the loan agreement between Liberia and
Ghana regarding the provision of 21,000 tablets and power banks respectively.
It means the government and its partners will have to allocate US$5,355,000 to purchase its own electronic gadgets, which will be associated with a long procurement.
The partners also warned about donor fatigue regarding the payment of nearly US$800,000 if the census isn’t held in October due to an agreement on the census project, which ends in December.
A postponement to December means the government and its partners must raise US$2 million amid global economic challenges.
In total, more than US$8.8 million would have been lost if the census wasn’t held in October.
“Your Excellency, the census is a legacy project for the government and its conduct will be a significant achievement for the citizens.
“If conducted in October, the census will be a milestone for Liberia to celebrate as it would: (a) provide the much-needed reliable data for development planning, (b) enable measurement of progress on national development and (c) inform the world in November of Liberia’s contribution to the global population of eight billion,” Niels wrote.
They have assured Weah of the necessary financial, technical, logistical and administrative arrangements that have been put in place to ensure that the census is held unhindered.
LISGIS has been working with the speed of light to meet these timelines.
A second application for field staff ended on 14 August with recruitment scheduled for August 29 to September 2 and training expected to kick-off mid-September to early October ahead of deployment on 15 October.
A national stakeholder engagement conference, in collaboration with the United Nations Population Fund (UNFPA), was held at the Monrovia City Hall on 26 August.
A meeting with House Speaker Bhofal Chambers and Deputy Speaker Fonati Koffa and the leadership; UNFPA Resident Representative Bidisha Pillai, LISGIS acting Director-General Wilmot F. Smith, Jr. and Deputy Director-General for administration Lawrence George took place on 23 August.
A national establishment census stakeholders’ workshop to ease data collection on the field was held with the business community on 16 August.
A capacity building strategy and action plan workshop to enhance statistical work in Liberia was held at LISGIS for national statistical systems on 12 August.
A 10-day training for the provisioning and to insert geographic and cartographic mappings on the tablets ended on 15 August while the coding on the tablets per county has started.
LISGIS and partners have been regularly meeting to ensure that census are held in October with preliminary results available on 11 November and final results on 25 November due to the digital nature which will enable the immediate transmission of field data to the data center once collected.
President Weah, based on the exigency of the issues raised, recalled the legislature from its constituency break on 9 August for a month (15 August to 13 September) to discuss and act upon matters of national emergency, including setting-up of a new census date.
LISGIS management and board chair Tweah are expected to appear before the plenary at the legislature on August 30 to explain why the census must be held in October. Liberia’s last census was held in March 2008. | <urn:uuid:63df6f93-8310-4f95-919a-cf8673362ac8> | CC-MAIN-2023-40 | https://knewsonline.com/international-partners-to-liberia-writes-pres-weah-on-2022-census/ | 2023-09-26T05:14:29Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.958672 | 1,106 |
11 great crowdfunding campaigns to check out in October
AR glasses, yard cleaning robots, and more round out our picks this month.
Crowdfunding is a cool way for innovative products to see the light of day without the restrictions placed on in-house development at large companies.
It’s also a great place to check out video games from small studios, movies, and campaigns for social good.
With all those campaigns competing for your attention, finding ones based on your interests can be tricky. Let KnowTechie do all the hard work for you with our picks of the crop for October.
Check out these 11 awesome crowdfunding campaigns this month
So… with how many crowdfunding campaigns are out there, how do you choose what to back?
Well, we use a combination of checking out their campaign page, looking to see if any of the comments on their prior campaigns show dissatisfied backers, and also companies we’ve already had successful pledge fulfillment from.
I also tend to stick to gadget areas we know a bit about, like photography, cooking, maker tools, and writing implements. That way, we can judge whether or not the campaign’s aspirations are within reach.
We also pick campaigns with some time left to run, as it’s no fun finding out about cool campaigns after they’ve finished.
So, with all of that out of the way, here are some of the crowdfunding campaigns we’ve found worthy of attention in October:
TCL NXTWEAR S XR Glasses
Augmented reality glasses are everywhere these days, and this pair from TCL looks pretty good. Housed in oversized sunglasses, the NXTWEAR S creates a virtual 140-inch screen in your field of vision.
Use them for gaming, watching movies, or for working discretely so nobody can see what you’re doing. They’re also compatible with smartphones, consoles, PC, and laptops.
Filters are an essential tool in every photographer and videographer’s kit bag. The thing is, most are full of frustrations as well. Maven aims to solve all those frustrations, so you can concentrate on creating.
Their filter system uses magnets to attach to your lens, not annoying threads that stick. They’re also color-coded, so you can tell which one you’re using at a glance.
Yarbo – intelligent yard robot
Hate mowing your lawn? Who doesn’t, but now you can outsource that job to robots with this new crowdfunding campaign. Yarbo doesn’t just keep your grass at HOA-approved levels though.
You can swap out its mower module for a leafblower or a mini-snowblower. No more back-breaking snow shoveling. Bliss.
Loona – The most Intelligent Petbot
Know someone who’d love a robotic companion for Christmas this year? Meet Loona, the crowdfunding petbot that looks like she rolled out of a Pixar movie.
Full of personality, she loves to follow you around like a real pet. She’ll quietly amuse herself if you’re busy too, and is packed full of AI technology to make her seem more alive.
Keychron K3 Pro
Keychron’s latest custom mechanical keyboard has low-profile Gateron switches, so the keyboard takes up less vertical space on your desk.
Multitask with up to three devices via Bluetooth 5.1, and get a 1,000Hz polling rate when connected via USB-C for fast responsive typing or gaming.
The K3 Pro is also compatible with VIA and QMK, the most widely used keymapping firmware. That means you can customize every key, including on-board macro functionality.
Horizon MFi and MagSafe 3-in-1 charger
Sick of having your desk or nightstand covered in chargers? Horizon charges your iPhone, AirPods, and your Apple Watch, all from a slimline device.
It also folds out to provide a handy stand for your iPhone while charging via MagSafe wireless. MagSafe, 10W Qi for your AirPods, and the fastest charge for your Apple Watch Series 7 or 8, all in one device.
Astronomy is cool, but this telescope crowdfunding campaign is even cooler. It’s packed with smarts to help you identify celestial bodies and automatically tracks them while taking images on its integrated imager.
That’s enough resolution to image faraway nebulae, or get high-resolution snaps of the planets in our Solar System. You also get a stainless steel tripod and app control with over 100,000 objects cataloged for easy viewing.
Carrying gear around is a pain, and all-terrain wagons get heavy and unwieldy quickly. Outisan’s new crowdfunding campaign brings an electric utility wagon with power assist motors in the wheels.
Those motors help on any terrain, but really come in handy when going up or down hills. Make light work of even the heaviest loads with this e-wagon.
Food waste is a big issue, and Shelfy wants to help. It uses photocatalytic filtering to make the contents of your fridge last longer.
No more bad odors, reduced bacteria, and food that lasts multiple times as long. That sounds like a winning combination to us.
What do you get when you put a bunch of skateboarders in charge of designing an e-scooter? You get the crowdfunding campaign Skate-X, and it’s gnarly.
20 mph top speed, 20-mile range, a minimalist frame designed to make it feel like carving on a skateboard, and a quality build informed by decades of experience.
You also get a 500W motor, headlights, taillights, turn signals, and both foot and handbrakes.
Rotolight NEO 3 PRO and AEOS 2 PRO
Rotolight is back, with pro versions of the two lights that set Kickstarter on fire in 2021. The Neo 3 Pro and Aeos 3 Pro dial up the features, making some of the best LED lights even better.
The Pro versions gain true aperture dimming, wireless trigger compatibility with the biggest brands, and over 100 preset light recipes.
That’s on top of the 2,500 digital filters and 16.7 million colors that you could already dial in. The result? The best small-factor LED lights just got better.
We’ve picked our favorite crowdfunding campaigns this month. It’s only a tiny cross-section of the crowdfunding space, which has something for everyone.
We hope it’s sparked some interest in the space, and we encourage you to browse for projects that might fit your interests more.
- The new Apple TV 4K comes with an A15 bionic chip and HDR10+
- Over-the-counter hearing aids are now available in the US
- The best gaming keyboards (2022)
- Microsoft’s Surface Pro 9 lets you pick from two different processors
Just a heads up, if you buy something through our links, we may get a small share of the sale. It’s but one of the ways we keep the lights on here. Click here for more. | <urn:uuid:33a3f774-3e77-4d57-9746-6d96ac03dd8f> | CC-MAIN-2023-40 | https://knowtechie.com/11-great-crowdfunding-campaigns-to-check-out-in-october/ | 2023-09-26T05:37:31Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.919193 | 1,550 |
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Conducting marketing of our own products and services without the use of electronic communications – Article 6(1)(f) RODO; Conducting marketing activities to promote our business.
Carrying out marketing activities of our own products and services with the use of electronic communication means – article 6(1)(f) RODO; however, these activities, due to other applicable regulations, are carried out by KOMA Sp. z o.o. only on the basis of the consents held. Conducting marketing activities to promote the activities carried out.
Handling requests sent using the contact form, other requests, including ensuring accountability (demonstrating that KOMA Sp. z o.o. fulfils its obligations under the law) – Article 6(1)(f) of the RODO; Responding to requests and enquiries sent using the contact form or in any other form, including storing sensitive requests and responses provided in order to maintain the principle of accountability.
To set up and manage your account created on www.sklep.koma.zgora.pl; to provide support for your account, handle transactions and resolve technical issues – Article 6(1)(a).
Do you have to provide us with your personal data?
There is no obligation to do so. However, you must bear in mind that your personal data is necessary for the processing of orders, so failure to provide this data or requesting its deletion will prevent us from carrying out the transaction.
Recipients of the data?
We may pass your personal data to other entities for processing, in particular:
to postal or courier companies
to banks, in case it is necessary to carry out settlements
to state authorities or other entities authorised by law, in order to fulfil the obligations incumbent on us (Tax Office, PIP, ZUS)
entities supporting us in our operations on our behalf, in particular third party system providers supporting our operations
Processing of personal data by automated means?
Personal data will not be processed in an automated manner (including in the form of profiling) in such a way that any decisions could be made as a result of such automated processing, that other legal effects would be produced or that our customers would otherwise be materially affected.
How long will data be stored?
Data contained on contracts and powers of attorney; Until the statute of limitations for contractual claims.
Settlement documents; Books and related documents until the expiry of the statute of limitations for tax liability, unless otherwise provided by tax laws.
Warranty-related documents; Warranty and complaint documents will be processed for 1 year after the expiry of the warranty or settlement of the complaint.
Data for marketing purposes; In the case of data processing on the basis of consent – until it is withdrawn; – In the case of data processing on the basis of KOMA Sp. z o.o.’s legitimate purpose. – Until an objection is lodged.
Data provided using the contact form; For a period of 3 years to maintain the principle of accountability.
What rights do you have?
Each data subject has the right of access to the content of their data and the right to rectification, erasure, restriction of processing, the right to data portability, the right to object, the right to withdraw consent at any time without affecting the lawfulness of the processing performed on the basis of consent before its withdrawal (as long as the processing is based on consent).
In addition, if the processing we carry out violates the provisions of the RODO, you have the right to lodge a complaint to the supervisory authority, i.e. the President of the Office for Personal Data Protection.
Provision of data is necessary to conclude a contract with KOMA Sp. z o.o.. For the rest, the provision of data is voluntary. | <urn:uuid:3b637ae5-9bd8-4092-98d7-69a40cda1731> | CC-MAIN-2023-40 | https://koma.zgora.pl/en/polityka-prywatnosci/ | 2023-09-26T05:56:09Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.905109 | 1,174 |
Deadline: 26 February 2021
We live in a world where technological advances and their effects are becoming more and more an issue involving of all of us, whether we live in the western or eastern hemisphere, in the global north or south. Rapid aging of the population, strategic functioning of the economic superpowers, ground-breaking technological applications, marginalization and exclusion of social groups, tensions between governments and non-governmental organizations, local and international conflicts, climate change, environmental problems and new healthcare challenges pose civilization challenges for mankind which require thorough consideration and active participation. New technologies, with their emancipatory neutrality, offer on the one hand the possibility of empowering civil society, and on the other increased control and concentration of power and capital.
We all face challenges which determine our future and the future of our children, so active participation in the konS project means promoting visionary, unexpected, different ideas allowing us to see beyond the determinism of rationalist western science and economics. Through our activity, we can encourage, inspire and empower decision-makers, scientists, engineers and economists in their actions that are inclusive, socially responsible and sustainable.
How will we support selected art projects?
Within this open call we plan to support up to 5 art productions of contemporary investigative art selected at the consortium programming council*. The art projects may already be in progress or they can be brand new, however they must be completed during the term of the financial mechanism (no later than April 2022). The value of financial support for each project is estimated at no more than 15,000 EUR. The funds are intended to cover the costs of development and realization of an artwork.
Production of selected artworks will be carried out in thematic laboratories of our partners and will be assisted by associate partners (Universities of Ljubljana, Maribor and Nova Gorica) and the project konS associate research and scientific laboratories and institutes (National Institute of Chemistry, Jožef Stefan Institute, and others). | <urn:uuid:98af800b-ab15-46e9-8041-90081202f7fb> | CC-MAIN-2023-40 | https://kons-platforma.org/en/open-call-for-submission-of-new-art-projects/ | 2023-09-26T07:04:09Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.915277 | 405 |
Rabbi Menachem Waldman is a central and veteran activist in the struggle for the aliyah and absorption of Ethiopian Jewry. For many years he served as the representative of the Israeli Chief Rabbinate on the matter of Ethiopian Jewry and headed the Shvut Am Institute. In recent years, he has directed the Jewish Agency’s Jewish education programs for Ethiopian immigrants. He has traveled to Ethiopia some fifty times as an emissary in order to guide the Jewish life of tens of thousands of Ethiopian Jews while they waited for Aliyah in Addis Ababa and Gondar. Rabbi Waldman is considered one of the foremost experts on the study of Ethiopian Jewry. He has published numerous books on the subject, including The Jews of Ethiopia: The Beta-Israel Community (1985); Beyond the Rivers of Ethiopia: The Jews of Ethiopia and the Jewish People (Hebrew, 1988); From Ethiopia to Jerusalem: The Jews of Ethiopia in the Modern Era (Hebrew, 1992); The Koren Ethiopian Haggadah: Journey to Freedom (2010); and Journey to the Remainder of Ethiopian Jewry (Hebrew, 2015). | <urn:uuid:c5e6ee91-c642-4830-8581-b0c6f77618ed> | CC-MAIN-2023-40 | https://korenpub.com/collections/rabbi-menachem-waldman | 2023-09-26T05:20:26Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.934434 | 232 |
“In this follow-up to Book 1, Donoghue similarly provides an Indiana Jones–like mélange of archaeology, treasure, villains, jungles, and ancient science. (Although it’s possible to follow this book as a stand-alone volume, it’ll make more sense read in sequence.) His characters are well-defined, important in a story so driven by the particulars of how an unknown technology works, sections that will be best appreciated by readers with a taste for engineering.”
Kirkus Reviews, June 13, 2017
See the full review here.
“This is the second installment in this series and I was able to pick up the story rather quickly from where it had previously halted. Although these are stand alone stories I would recommend reading them in order. That way you can immerse yourself into the flavor of the writing as well as the storyline. Will Anlon, and friends, be successful in their quest? Each book stops at a logical place and time but leaves the reader waiting on the next chapter in this brilliant adventure series. I have given this book a 4.5 star rating and would recommend it to anyone seeking a semi magical adventure story.”
Frank Peters, Book Him Danno Blog, July 13, 2017
“I have read both books in this series and can hardly wait for number 3! Well written with enough mystery and drama to make me want to keep reading. Extremely interesting!” Amazon rating: 5 out of 5 stars.
Georgia Merriman, July 4, 2017
“Loved Shadows of the Stone Benders. Loved Race for the Flash Stone. Cannot wait for the next installment. I just know I know who The Betrayer is! The Anlon Cully Chronicles are on my must read list!” Amazon rating: 4 out of 5 stars
Mark Easter, June 29, 2017
“Again the characters are well done. Some continue from the first book and some are new. Also as in the first of the series the stones from this ancient civilization play an important role. This requires a bit of suspending disbelief but again I was happy to do that from a good story. I enjoyed learning more about the civilization that made these stones. Along the way there were many twist and turns and a good read.”
Jack Reidy, June 24, 2017
“Complex, interesting characters with archeological finds and a wonderful innovative old culture, the Munuorians. Hard to tell initially who all of the villains where, a great mystery.” NetGalley rating: 4 out of 5 stars.
Margaret Holmes, June 24, 2017
“I recommend this novel to those who enjoy an Indiana Jones type of adventure. You’ll be entertained and read some interesting ideas about archaeological mysteries.” Amazon rating 4 out of 5 stars
Joan Nienhuis, June 15, 2017
“I really enjoy this series, it’s not super-fast paced, but it chugs along with enough speed to keep my attention focused. It’s also interesting to consider the what ifs. What if an ancient culture had the abilities described? How much easier would it have been to construct the pyramids or raise Stonehenge? I can’t wait to see where in the world the next book in the series takes the reader.” Amazon rating: 5 out of 5 stars
Sarra Lord, June 7, 2017
“I love archaeological mysteries, fantasy, thrillers, and action. This book has all this and more. I read the first book and loved it. This book is even better. I give this a BIG 5 STARS. I loved the plot, characters, the whole premise of the book had me right away and I read it all day! Wow, now, book 3? I am so mad at my self for not reading it sooner!!! Excellent book. Putting this one in my favorite list!” Amazon rating: 5 out of 5 stars
Montzalee Wittmann, June 6, 2017
“Book one had me asking–‘A fascinating concept of a very long ago culture that had the power to control things through stones. (That doesn’t really do it justice, but it’s complicated.) The obvious question is who killed whom and why? But more important is, what are these stones, what can they do, and what are they really for? The exploration is well worth it. Somewhat psychedelic in some aspects, so just suspend disbelief and enjoy yourself.’ Book two is that and then some! More layers of the mysterious civilization’s past are revealed. More powers/abilities of the stones are discovered or learned. It’s never a dull moment. Book three should be a real trip!” Amazon rating: 4 out of 5 stars
Libby Dodd, June 3, 2017 | <urn:uuid:9f0dfeab-44a5-4a5d-b0c4-3c9395e5aff3> | CC-MAIN-2023-40 | https://kpatrickdonoghue.com/praise-race-flash-stone/ | 2023-09-26T06:39:14Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.957843 | 1,021 |
Hello. I’d like to order a necklace from you using KRFTR colors, purple and orange. I also use yellow and blue if you need more colors. I’m not sure what to put for the time frame so just let me know. Thank you!
I really love this necklace on your website: https://pizazzstudios.com/collections/necklaces/products/ocean-inspired-pendant-necklace | <urn:uuid:9766459f-8df4-4aa0-a457-207606cc34d5> | CC-MAIN-2023-40 | https://krftr.com/product/necklace/ | 2023-09-26T05:21:05Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.834852 | 98 |
A dynamic and advanced disciple of Gurudev Paramahamsa Hariharanandaji, Swami Shuddhananda Giri was formerly an engineer in his worldly life. From the days of his childhood, he cherished an intense desire for spiritual knowledge; thus it was not unusual to find him meditating or studying the various scriptures of the world. When he was yet a young man in his early twenties, his fervent desire for Truth led him to the holy feet of his Master, who initiated him into the monastic order in 1995, the same day our beloved Guruji Paramahamsa Prajnananandaji was christened as a monk in Kolkata by Shri Gurudev. After taking his vows, he then went to Yuktashram, Bhisindipur, to do intense sadhana and meditate, as directed by beloved Gurudev.
Swami Shuddhanandaji is a highly regarded world teacher of Kriya Yoga and practical spiritual wisdom. He has traveled extensively around the world, visiting such countries as the United States, United Kingdom, Africa, Australia, Brazil, Canada, as well as many countries throughout Europe, conducting Kriya Yoga programs and delivering discourses on various scriptures and philosophy. During his travels abroad he has also visited many universities, enlightening students about the value of yogic philosophy and meditation.
Swamiji served as Secretary of Prajnana Mission from 1999 until 2006, as Vice President from 2006 to 2008, and as President from 2008 to 2014. Along with his multifold and diverse responsibilities, Swamiji graciously finds time to organize Kriya Yoga retreats in the Himalayas for kriyavans. | <urn:uuid:965382eb-0433-4f5a-8a0e-57e56918a8c1> | CC-MAIN-2023-40 | https://kriya.org/swami/swami-shuddhananda-giri/en | 2023-09-26T07:03:41Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.984563 | 351 |
Inside the Life of a Parent on Deployment
Becoming a parent is likely the most significant challenge many will face. Parents spend months and months preparing for their child yet still have so many unanswered questions when they arrive. Then 2020 hit, and the routine for parents was changed drastically. Instead of getting your children ready to get on the bus, you are now waking them up so they can sit at the kitchen table to log on to their computers for class. Parents quickly gained the label teacher, cafeteria worker, classmate, and so much more. Many parents had to learn the technology their children needed quickly to succeed in school.
The pandemic greatly affected many working parents. They scrambled to adjust their work schedules or find people to watch their children so that they could continue to provide for their families. For many medical professions, they started looking into other options to ensure they could provide for their loved ones. One Krucial Krew Nurse Ivyonne talks about the struggles of being a parent while on deployment.
“The biggest challenge I faced while I was on deployment was being away from my two- and three-year-old. I had never been away from them longer than 24 hours, and here I was, signing up for a two-week contract and possibly longer! [The] only way we had to keep in touch was through FaceTime. It always brought tears to my eyes, especially because they did not understand why I was away from them for so long. Given another chance, I would most definitely go again. My husband has proven himself extremely capable of caring for our girls in my absence. Krucial was the first company I had heard of when they started the pandemic relief in New York City.
“After I gathered myself, I knew [Krucial was] who I wanted to go with [to help others]. COVID-19 is and was a challenge, and Krucial was up for it; I was too. It was hard. The numbers were rising and rising. I knew I had to do something; we all had to do something. One patient a day, that was my motto. I made it my duty to speak positivity into them even when they felt defeated—some happy moments when I wheeled them out of the hospital stable. Sad, when I looked in their eyes, and I knew it would be a difficult fight. Sometimes COVID-19 won.
“This pandemic is my why. I’ve heard and read of such times. This is my first experience [traveling], and I have a front-row seat. I’m here to answer the call; I’m here to fight this monster. I’m fighting for my patients, my family, and my friends. All of us in this together. I hold my patients’ hands for their families who cannot be there with them when they need them the most. I am their nurse.”
Ivyonne, along with many other parents, chose to leave their families for numerous reasons. Still, one common motivator is to help those during their most significant time of need. They have given up on many memories with their loved ones but gained so much during their deployment. Their selflessness and kind heart do not go unnoticed.
Krucial cannot thank the parents who have deployed with us or will deploy with us in the future enough. We see and hear you. We understand the struggle and sadness that comes with watching your children grow up via Facetime. You are a true hero.
If you are a parent who has deployed with Krucial, please remember: You are the reason patients keep fighting. You are a fighter and giver. We are here to remind you that you are an incredible parent and person. Our compassionate Krew has touched many lives. Thank you. | <urn:uuid:9b3e1e79-d76b-43c3-afcc-ada5134ee608> | CC-MAIN-2023-40 | https://krucialrr.org/2021/02/inside-the-life-of-a-parent-on-deployment/ | 2023-09-26T05:45:23Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.988214 | 780 |
Creator: David Rumsey, President, Cartography Associates, San Francisco, California
The Past as a Foreign Country: Exploring Historical Maps on the Internet[quote]It appears that the operational domain of the mapping discourse extends far beyond the knowledge of space and enters our memory as well. In fact, it is through this mediation of historical maps that the domains of space and memory, with knowledge and sentiments, are transgressed. Thongchai Winichakul, Siam Mapped 1[/quote] Historic maps are much more than sources of archaic place names, locations of ancient settlement, or clues in the search for elusive lacunae in the historical record. Historic maps can be emblems of shared heritage and national narratives. They may be objects of beauty, creativity, imagination, and skill. They may also be handmaidens in nation-building and projects of imperial destiny, serving quests for territory, knowledge, and power. Historic maps are the two dimensional visions of a reality filtered through the imperfections of human understanding
Access to historic maps for education and research has been greatly enlarged by the world wide web. Like other kinds of important research resources – manuscripts, inscriptions, visual arts – historic maps can be studied in a digital environment in ways once impossible. Fragile texts can be photographed once and shared with thousands. Digital objects can be studied at leisure, magnified until the image finally dissolves in pixillation, combined for close study with digital objects drawn from collections continents apart. If the digital simulation represents a compromise with the texture, or aura, or tactile presence of its original, it nonetheless can offer rewards far more widely shared.
One of the finest websites for digital historic maps is davidrumsey.com. The website is a resource for teaching and research, and a model for possible future work in the area of Southeast Asian maps. It is not only of great potential use to those seeking historic map materials, but for work with maps as suggestive of cultural ideas, conceptions of space, and the political, economic, and social concerns of their era. In an era when metaphors of “mapping” are widely used in other disciplines, interest in maps and spatial information and its modes of representation and mediation seem also to be growing.
There are now many sites for maps on the web, most centered upon particular collections, some primarily portals to other resources. Highlights of this site include:
- the quality of the images in the on-line collection,
- the inclusion of Geographic Information Systems features, which can greatly expand possibilities for spatial analysis and data integration from multiple sources
- the moves toward expanded utility through interoperability with other on-line resources both in terms of search capability and display or results together with other related resources (such as art images).
This dataset review will comment on the scope and quality of the site both in terms of technology and content. The site was intended for educators, researchers, and those with historical or map interests generally. Users are reported to include K-12 teaching resource groups, university map libraries, history departments, to name a few. 2 Though Southeast Asianists are not by any means a primary intended audience, the site is useful particularly as a general existing map library resource, and as a model for what would also be possible in the Southeast Asia context.
Stability is one of the major concerns plaguing web-based research. While library books can be counted upon to remain on library shelves for years, decades, even centuries, websites appear, evolve, and disappear. Even sites with excellent content vanish. Backing by an established educational or governmental institution does not guarantee internet longevity, as instututional priorities and budgetary considerations change. Davidrumsey.com represents essentially the work of an individual specialist with vision, commitment, and resources. For a site based on an individual’s collection and personal resources davidrumsey.com promises stability and growth greater than many institutional sites. Davidrumsey.com first went online in March, 2000, has grown five-fold since its launch, and is poised to expand into greatly enhanced capacity as an online digital library hosting major image collections as well as maps.
The original maps are part of Rumsey’s collection, and the digital images created in his studio in San Francisco. As the maps are historic rather than contemporary, they are out of copyright. As owner of the artifacts as well as creator of the digital versions, David Rumsey holds copyright to all map material on the site, and chooses to waive restriction for educational use of the online collection. The online map archive now numbers some 10,000 maps. As the original historic map collection numbers some 150,000 items, this still represents under 10 percent of the available collection. The total current online count for Asia is about 500 maps, or less than 5 percent of the online collection. The focus of the collection is the Americas, though there are maps of all regions of the earth. Maps, atlases, globes, charts, and other representations of the earth’s surface are included. Special projects have brought additional map collections within online archive, such as digitizing the Japanese map collection at the University of California, Berkeley. This is one of the largest collections of Japanese maps in the world. Thus far 209 images from the maps and books have been included. The site continues to grow at a rapid pace.
The online documentation was developed for the original map library. Users can view the map metadata online, as well as retrieve map documentation from the original collection. The site is not managed or peer reviewed by an academic institution. However, Rumsey, through his association with Luna Imaging, Inc. and other collaborations, has been working with a number of high-profile museums and universities. The site is frequently updated, not in terms of eliminating obsolete data but adding to the online collection. Because the site focuses on historic maps, it is not time-sensitive in the way that sites dealing with current issues would be.
The greatest asset of this site is the quality of the images in the database. The images have been digitized at very high resolution. With on-screen magnification, even very fine detail can be seen and place-names read. This greatest of assets is also a liability in this respect: for those with inadequate internet connections, downloading these images can take time. This is a site with great rewards for the high bandwidth user. This is a concern for users in Southeast Asia, where high speed access is at best uneven. For those who do have good connections and access to good printers, images can be printed out of very high quality, approaching the look of map facsimiles.
The site employs Luna’s Insight® software for the map image database. This software has been widely marketed to museums with digital collections in the United States. The software has an elegant interface and ease of navigation. Several search options are open to users, including spatial and keyword searches. But its primary advantage is delivery of high quality images with flexibility of search and display. The resolution is such that images can be magnified to see even the smallest details.
The disadvantage is that this is proprietary software. The major concern with proprietary software, aside from cost, is that the company may reach a point where their products are no longer supported, or the company may disappear altogether. While the software is now used by a number of major institutions, suggesting confidence in its longevity, there are few guarantees on the internet. A further issue is the interoperability with other sites that employ Insight software. A consortium of museums and other cultural institutions using this software (including the site here under consideration) has formed searching across collections. This search capability is not at present available to the public, though plans are underway to develop a site that makes this available.
Users have two options for accessing maps in the website map collection: view images online with the internet browser (viewer), or download and install a feature-rich Java client. The customized ArcIMS (Internet Mapping System, a product of the ESRI software firm) site, developed with Berkeley-based Telemorphic Inc., allowed “quad view”: up to four images can be selected for view simultaneously, to compare layers in time. A drawback of the site, noted above, is slow download time due to the large file size of high resolution images. The Insight Browser and the Java Client can take up to one minute to load with a 28k modem, for example, though subsequent downloads tend to be shorter as some data is then cached locally.
The site is unusually clear about its technical requirements. These are listed on a menu on the home page of the site, with each of four available search options: the internet browser and java client described above, as well as a GIS (Geographic Information Systems) browser, for the small but growing GIS component of the collection, and the “Collections Ticker.” The Collections Ticker is a Flash-based thumbnail viewer that allows users to “scroll” through thumbnails and short descriptions of the entire collection of maps, charts, globes and other items (similar to a news or stock ticker). Also on the front page is “Help” access for users, and warnings of a few common problems likely to be encountered.
The site has examples of other technologies for spatial visualization. There are currently five maps in 3D that must be viewed in the 3D browser (http:www.davidrumsey.com/GIS/3d.htm). There are 123 georeferenced maps available now, mostly maps of the US andJapan, with numbers expected to grow The GIS browser (http:www.davidrumsey.com/GIS/index.htm) allows users to combine historic maps with layers such as satellite imagery and aerial photography. This is an area of considerable potential, especially for Southeast Asia, where satellite and aerial images are playing an increasingly important role in historical study.
A less exacting (and less time-consuming) but much more broad-based geo-referencing is being made available by ECAI (Electronic Cultural Atlas Initiative), with current count at 8,000 maps, or about 2/3 of the online collection. The balance of the online collection is scheduled to be completed by May, according to Dr. Ian Johnson, an archaeologist at the University of Sydney who is directing the project.
Metadata, or the descriptive terms for the “digital objects” (in this case maps) are registered in the ECAI Metadata Clearinghouse at theUniversity of Sydney (http://www.timemap.net/clearinghouse/html/index.html). These georeferenced maps can be retrieved from davidrumsey.com by spatial or keyword search at the Metadata Clearinghouse site, downloaded, and included in user-authored “map-spaces” along with other datasets downloaded from the internet or cached locally. Layers of overlaid maps from different eras help visualize changes over time for a specified area.
For those who wish to see examples of projects in which maps have been geo-registered, several are now available at the site, all from the U.S. or Japan at present (San Francisco, Los Angeles, Yosemite, Tokyo, Kyoto, Osaka). Projects will soon be online for New Yorkand Chicago as well. There is also one regional project, which follows the early nineteenth century journey of Lewis and Clark across western North America. Regional projects pose significantly greater problems than urban ones, as the latter encompass limited land area and can work at far larger scales. It is hoped that future studies can be done for Southeast Asia. An even more positive development would be a Southeast Asian scholar or organization that undertakes to produce similar projects with this work as a model.
Rumsey has made “fly-through” animations of some of his maps, using ArcScene to overlay his maps on a Digital Elevation Model (DEM), which provides the earth’s topography. The results may speak the language of young people already well accustomed to digital gaming environments. For others less familiar with the technology, the thrill of movement through digital space, guided by the cursor, may be even more impressive. This approach captures interest and, couched in guided learning environments, may be productive in encouraging new ways of seeing and experiencing historic maps, contemporary spaces, and spatial information. Concern has been expressed in relation to this site, as well as virtual reality and enhanced digital environments generally: that the technology overpowers the content, and showmanship the scholarship. Rather than eschew the approach, the most helpful reaction seems to be for the academic community to acknowledge the caveats, as should be the case with all digital technologies scholars employ, accept that this is the direction technology is moving, and as opportunity arises remain vigilant in insisting on scholarly merit and context behind examples employed for classroom or research use.
Davidrumsey.com gets approximately 6500 “hits,” or website visits, per day, suggesting widespread access. It is not as yet possible to analyze the countries of inquiry origin. The site is linked to other online resources and portals. As well as going directly to davidrumsey.com, popular search engines such as google greatly expand access to the collection. The site generates individual Web pages for each record, and the Google data “spiders” catalog and index these records. Records are filed with other sites, both educational and commercially-sponsored, including the Open Archive Initiative (http://www.openarchives.org/, sponsored by the US government), the California Digital Library (http://www.cdlib.org/, run by the University of California President’s office), and the Geography Network site (http://www.geographynetwork.com/, run by ESRI, one of the leading commercial Geographic Information Systems developers.
Though this site is a .com, rather than a .edu or .org, the motivating spirit is a philanthropic one. There is no charge for access to any of the maps. All images are accessible and downloadable. Copyright is held by the collection owner, Mr. Rumsey, and he has waived copyright privilege in favor of enriching the scholarly and educational capacities of internet users through his online collections. Thus anyone who wishes to use his online collection for educational or scholarly purposes is free to do so without restriction.
Related interoperable resources are available on other sites, but not always offered as freely. The digital image archive of the Art Museum Image Consortium (AMICO, on the web at http://www.amico.org/, and linked to the davidrumsey.com home page) can be searched and search results displayed together with Rumsey’s maps. AMICO is a non-profit organization of museums, including many of the significant collections in the U.S. The digital archive includes over 100,000 images from prehistoric to contemporary arts. The project is the result of an agreement between David Rumsey’s organization Cartography Associates and AMICO, linking the collections of the two archives. AMICO’s collection bias is decidedly Western, but does include some Asian. Unlike davidrumsey.com the AMICO site’s resources are available on a membership basis, with a rate currently of US $150 annually for access to 118,000 images of art.
It is in the potential for expanded use of the collection through interoperability with other resources that the greatest significance for the future lies. The expansion of this site into the digital library realm, and the cross-search options with other search features and digital collections enlarge the utility of the site. The use of GIS to combine maps with other data and spatial information provides a model for integrated research resources. Davidrumsey.com, developed for and centered upon the map collection owned by its creator, is poised for a major shift in the future, expanding from a specialized map library to a larger digital library of other kinds of images. Thus far the collections of images are datasets related to specific institutions or projects. For example, one upcoming collaborative project is mounting 5,000 images from the National Palace Museum in Taipei, spanning seven millennia of Chinese history. Future site development is planned to include expanded inclusion of important digital image collections.
Users of the site are encouraged to provide feedback on their experience with the website reviewed in this issue. Kyoto Review invites readers to suggest useful datasets, particularly datasets based in Southeast Asia, for future review. Comments and suggestions should be sent to firstname.lastname@example.org.
Caverlee Cary is a staff research associate at the Geographic Information Science Center, University of California, Berkeley(gisc.berkeley.edu), and serves as Editor of ECAI Southeast Asia (ecai.org). 3
Kyoto Review of Southeast Asia. Issue 5 (March 2004). Islam in Southeast Asia
Picture below: A comparison of two historical maps showing Southeast Asia, both published in 1844. The map on the left is “Hinter Indien,” drawn by German Cartographer Carl Radefeld. The map on the right is “Burmah, Siam, and Cochin China,” drawn by British Cartographer John Arrowsmith. Both maps look similar when viewed in their entirety (see “Digital Dataset Critiques” in Editorial). When zoomed in close (below), we can see abundant and interesting differences in physical features, toponyms, and political delineations. Digital imaging allows this kind of examination on the Web.
- Thongchai Winichakul, Siam Mapped. A History of the Geo-Body of a Nation (Honolulu: University of Hawaii Press, 1997), p. 154. ↩
- David Rumsey, “Tales from the Vault: Historical Maps Online,” Common-Place 3(4), July 2003, http://www.common-place.org/vol-03/no-04/tales/. ↩
- The author acknowledges with gratitude the assistance of David Rumsey, Anna Miller, Jeanette Zerneke, Samuel Otter, and John Radke ↩ | <urn:uuid:a1bd5ada-7641-4466-a61c-b75b6e0d52ea> | CC-MAIN-2023-40 | https://kyotoreview.org/issue-5/review-david-rumsey-on-line-historic-maps/ | 2023-09-26T04:57:10Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.931364 | 3,741 |
* We are in the process of migrating our old softwares to github. Contact us if you need help.
RIMBANET (Reconstructing Integrative Molecular Bayesian Network): RIMBANet is a software package for reconstructing integrative molecular Bayesian networks. There are multiple sources of perturbations (eg. genetic mutations, copy number variations, methylations and etc.) that may contribute aberrant behaviors of biological systems such as cancer cells. Cells employ multiple levels of regulation that enable them to respond to genetic and environmental perturbations. At the transcriptional level, abundance of mRNA can be affected by the rate of transcription, a complex process regulated by transcription factors and enhancers, and by the rate of degradation of transcripts, a process regulated by RNA binding proteins and, in many organisms, microRNAs. Protein abundances are determined by protein degradation and protein synthesis rates, where protein synthesis can be regulated by translation initiation factors and microRNAs. Protein activity depends on a number of factors in addition to protein abundance, including protein localization, phosphorylation states and other post-translational modifications, and protein-protein interactions. In addition to transcript and protein levels, the abundance of small-molecule metabolites is also tuned in response to changes in a cell’s physiological state.
One of major goals of systems biology is to understand how these genetic and environment variations drive transcriptional networks, protein-protein interaction networks, metabolite networks and etc. to give arise to complex phenotypes. The integration of genetic variation and intermediate observations such as mRNA variations into probabilistic causal models that can dissect genetic pathways and provide mechanisms connecting DNA to clinical outcomes. We developed a computation framework centered around Bayesian network and implemented it in RIMBANet (BN4Distribution.tgz), which is freely available for download. We have previously used RIMBANet to discover causal relationships in complex human diseases such as diabetes and obesity and yeast model.
We applied RIMBANet to investigate how genetic variations regulate transcriptional and metabolite level changes in yeast. The full data set used in the study is available here (Yeast_4_Distribution.tgz).
MODMacher (Multi-Omics Data Matcher): Errors in sample annotation or labeling occur frequently in large-scale genetic or genomic studies and are difficult to be completely avoided in the process of data generation and management. Identifying and correcting these errors are critical for integrative genomic studies. Different types of genetic and genomic data are inter-connected by cis-regulations. Based on these cis-regulations among different types of data, we develop a computational approach, named Multi-Omics Data Matcher (MODMatcher), to identify and correct sample labeling errors in the multiple types of molecular data that can be subsequently used in further integrative analysis. Our results indicate that inspection of sample annotation and labeling error is an indispensable data quality assurance step. Application to a large lung genomic study identified greatly increased statistically significant genetic associations and genomic correlations, a more than two-fold improvement. A simulation study shows that MODMatcher using three types of omics data is more robust than MODMatcher using two types of omics data. Details are described in Yoo et al (PLoS Comp. Biol, 2014).
ActMiR (Activity of miRNAs): MicroRNAs post-transcriptionally regulate a large number of mRNAs and play a key role in regulating cell growth, differentiation, and apoptosis. However, miRNA expression level is not equivalent to its functional activity (Mullokandov et al., 2012). We developed a computational approach to explicitly infer the activity of miRNAs based on the change in the expression levels of target genes. We showed in multiple cancer types (such as breast cancers, ovarian cancers, and GBM) that our estimated miRNA activities were consistently associated with clinical data in multiple independent data sets while the associations based on miRNA expression level itself couldn’t be replicated. The result is published in Lee et al. (Bioinformatics, 2015).
DDSClassifier (Deconvoluted Disease-Specific Classifier): Diagnostic and prognostic models based on peripheral blood gene expression have been reported for various types of disease. However, whole blood gene expression represents a mixture of hematopoietic cells, and is greatly influenced by the cell type frequency. Multiple common pathological and physiological changes result in similar blood cell type frequency change, which affects blood-based biomarkers’ specificity.To address these issues, we carried out a meta-analysis of 46 whole blood gene expression datasets covering a wide range of diseases or physiological conditions. Our analysis shows a striking overlap of signature genes shared by multiple diseases, which is driven by the underlying common patterns of cell component change. These observations suggest the necessity to develop disease-specific classifiers that can distinguish different disease types as well as normal controls. To build such models, we develop a new classification strategy that can take into consideration of both cell component changes and cell molecular stage changes. Particularly, we deconvoluted the original gene expression profile into a cell component profile and a residual expression profile for each sample, and built classifiers based on these deconvoluted features. Testing independent datasets, we show that the classifiers with cell component profiles and residual expression profiles incorporated performed significantly better than those without. Both the assembled datasets and the algorithms developed can be found in the R package. A detailed document can be found here. The result is published in Wang et al. (Scientific Reports, 2016)
DeClust: A reference-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles
HBVIntegrationPipeline : A robust data analysis pipeline was developed by modifying several key steps in VirusFinder2 for identifying HBV integration sites in both DNA and RNA sequencing data. A detailed description of the pipeline and proof-of-concept study results are published in Yoo S, Wang W, et al (BMC Medicine, 2017).
Multi-polynomial Temporal Genetic Association (MPTGA) and Temporal Genetic Causality Test (TGCT)
Methods to leverage both temporal and genetic information in association and causality test.
HBVIntegrationPipeline_single_cell: A specific pipeline for single cell HBV-HCC
proMODMatcher (probabibilistic Multi-omics data matching method): Data errors, including sample swapping and mis-labeling are inevitable in the process of large-scale omics data generation. Data errors need to be identified and corrected before integrative data analyses where different types of data are merged based on the annotated labels. We developed a robust probabilistic multi-omics data matching procedure, proMODMatcher, to curate data, identify and correct data annotation and errors in large databases. The proMODMathcer can be used to check potential labeling errors in profiles where the number of cis-relationships is small, such as miRNA and RPPA profiles. | <urn:uuid:fdfa80b8-1f4c-49fa-b863-625183b1c964> | CC-MAIN-2023-40 | https://labs.icahn.mssm.edu/zhulab/?s=rimbanet | 2023-09-26T06:19:47Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.910837 | 1,457 |
Dry eye can be very uncomfortable and may cause more serious problems if left untreated. Fortunately, dry eye can easily be diagnosed and treated by one of our optometrists here at Louisiana Eye & Laser Center. Think you may have Dry Eye? Read on below to learn more about the common symptoms of the condition, or request an appointment online for a Dry Eye consultation.
What is Dry Eye?
Everyone needs tears in order to nourish and lubricate the eyes. Every time you blink, tears lubricate your eyes, reducing the risk of infection and washing away foreign matter. Dry eye is a condition in which a person does not produce enough quality tears to nourish and protect the eyes. Symptoms include dryness, burning, and redness in the eyes. In general, there are two reasons that dry eye can occur:
- Not enough tears – Tear production generally decreases with age. It can also be impacted by certain medical conditions or medications. If environmental conditions cause tears to evaporate too quickly, dry eye can also occur.
- Poor quality tears – Tears are made up of water, oil, and mucus. A lack of any of these layers can lead to dry eye symptoms. The most common cause of dry eye occurs when the water layer is inadequate, causing a condition called keratoconjunctivitis sicca (KCS), which is known as dry eye syndrome.
If untreated, dry eye can lead to damage to the front surface of the eye and impaired vision.
What causes Dry Eye?
Dry eye is most commonly associated with age and gender. A majority of people over the age of 65 will experience symptoms of dry eye. Women are particularly vulnerable to experiencing dry eye symptoms. However, dry eye can affect individuals who live in dry or windy environments, regardless of age or gender. It can also be a side effect of some medications. Individuals with rheumatoid arthritis, diabetes, or thyroid problems are more likely to have symptoms of dry eye as well.
What should I do if I think I have Dry Eye?
Dry eye can be diagnosed through a comprehensive eye exam here at Louisiana Eye & Laser Center. An optometrist in one of our offices may evaluate your medical history to determine any general health problems, medications, or environmental conditions. An external examination of the eye, including lid structure and blink dynamics, can also help an optometrist determine if you have dry eye. One of our eye doctors will likely evaluate your eyelids and cornea using bright light and magnification. If necessary, tears can be tested for quantity and quality, including any abnormalities or imbalances that would lead to dry eye.
Self-care remedies include blinking regularly, increasing the humidity at home and work, wearing sunglasses, and taking natural supplements that include omega-3 fatty acid. You should also avoid dehydration by drinking 8-10 glasses of water per day. If necessary, your optometrist may prescribe or recommend an eye drop or artificial tear solution. In severe cases, it may be necessary to conduct a procedure to block tear ducts or to perform surgery.
Visit Louisiana Eye & Laser Center for Dry Eye Consultation and Treatment
At Louisiana Eye & Laser Center, we have over 40 years of experience treating patients and delivering excellent customer service. We have cutting-edge technology and some of the best practitioners in the state of Louisiana. If you think you may be suffering from dry eye, come visit one of our 14 offices right here in Louisiana! | <urn:uuid:458138e4-38ed-4964-aabd-88d728828135> | CC-MAIN-2023-40 | https://laeyeandlaser.com/how-do-i-know-if-i-have-dry-eye/ | 2023-09-26T05:38:28Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.930761 | 709 |
- This event has passed.
Weston Roundtable Series: How to Help Protect the Amazon
September 16, 2021 @ 2:15 pm - 3:30 pm
Register here for zoom link: https://go.wisc.edu/weston_
Brazil’s former Minister of Environment, Marina Silva, will discuss the challenges we need to face in order to preserve the Amazon and its indigenous population in the context of the multiple crises that Brazil and the world are currently experiencing. These reflections are the result of more than 30 years of socio-environmental activism in Brazil. | <urn:uuid:c6873bb4-513f-434e-adaf-06c36d7e3768> | CC-MAIN-2023-40 | https://lais.ucsb.edu/event/weston-roundtable-series-how-to-help-protect-the-amazon/ | 2023-09-26T05:26:05Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.929591 | 119 |
La Liga defending champions Atletico Madrid will travel to Italy and face AC Milan at the San Siro in the second gameweek of the UEFA Champions League 2021/22. The home team lost their opening match of Group B against Liverpool, and Atletico played out a goalless draw against Porto.
Let us take a look at the stats of both the teams in their previous match.
AC Milan lost their opening game of the group against Liverpool at Anfield by a scoreline of 2-3. The Italian giants sit at the bottom of the table after round one and will look to bounce back against the Spanish team.
Ante Rebic led the line for the Rossoneri and the team lined up in a 4-2-3-1 formation against Liverpool. Rebic and former Real Madrid player Brahim Diaz scored the two goals for the Italian club towards the end of the first half. The above viz shows the creation zones and the expected threat from passes. AC Milan attacked from the left side and youngster Rafael Leao operates from that side for the club. He was supported by Theo Hernandez and the visual shows that they are much stronger going forward from that side. Some of the play was also created from right, but the players were unable to get into the box from that side.
AC Milan attacked well against a very dangerous Liverpool team, but their defenders were unable to win most of their defensive duels. Milan led the scoreline by 2-1 towards the end of the first half. The team was unable to defend and conceded within the first three minutes of the second half. The four defenders and two central midfielders contested 56 duels in the whole match. They only won 14 duels, lost 31 defensive duels and the rest of the duels were neutral.
Rafael Leao was a constant threat from the left side and the Portuguese even provided an assist in the match. Tomori was also good defensively and the Englishman won five defensive duels and lost only one duel in the process.
Tiemoue Bakayoko, Rade Krunic, Alessandro Florenzi and Zlatan Ibrahimovic will be the notable absentees for the home team.
Atletico played out a 0-0 draw at home against Porto in their first match. Both the teams created very few chances in the match.
Simeone played a 3-4-2-1 formation and Suarez led the line for the team. He was supported by Lemar and Felix. Luis Suarez attempted three shots towards the goal but was unable to score. Atletico players were defensively sound and Jimenez was the most impressive defender. The Uruguayan won five aerial duels, made three recoveries in the opposition box and even delivered six passes into the opposition final third. The team made 27 recoveries in the opposition half.
Atletico main problem in their previous game was scoring goals and creating enough chances. The Spanish team only attempted six shots and two shots were on target. The shot map shows that only two shots were attempted from inside the opposition box and the rest of the shots were long-range efforts.
Savic is still suspended for the away team, but Koke, Felix and Lemar could feature after missing the recent matches due to injury.
Both the teams will look to bounce back after disappointing results in the first round. Atletico will look to defend and Simeone will expect his forward players to score their opening goal of the campaign. Milan will have a hard time scoring against a tight Atletico match. | <urn:uuid:e967b05b-4a6c-4ce3-8075-453b36efa398> | CC-MAIN-2023-40 | https://laligaanalysis.com/analysis/uefa-champions-league-2021-22-preview-ac-milan-vs-atletico-madrid | 2023-09-26T05:17:04Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.9813 | 725 |
Throughout his musical career, Nine Inch Nails founder and leader, Trent Reznor, has seen his fair share of ups and downs. Reznor has released nine albums under the Nine Inch Nails moniker, has won two Grammy awards, and has even appeared in a number of movies including The Social Network, which he won a Golden Globe and Academy Award for. Despite the success that he has seen over the past thirty years, Reznor had to go through hell and face his demons to become comfortable with himself and the fame he has received.
In 1994, Nine Inch Nails released The Downward Spiral. The title coincided with Reznor’s own downward spiral he was experiencing in his life as he struggled with drugs, alcohol, depression and the death of a family member.
The problems that he was facing were amplified by the newfound fame that he was receiving along with the critical praise from The Downward Spiral. Eventually, Reznor completed rehab and saved himself, but he considers it to be the hardest thing he’s ever done.
“My way of dealing with life was to numb myself with drugs and alcohol, because it made me feel better and more equipped to deal with everything.”
Trent Reznor was born on May 17, 1965, in Pennsylvania. Before achieving fame as the leader of Nine Inch Nails, Reznor played for a number of bands in Cleveland, Ohio. Eventually, Reznor landed a job at a recording studio in the city, working as an assistant engineer and janitor. Reznor was able to convince the studio owner to allow him to use unused studio time and after the studio closed to record demos for his own songs.
While he was still assembling the Nine Inch Nails band, Reznor decided to move forward with recording the music, electing to play most of the instruments himself. After completing the demo, Reznor and Nine Inch Nails made their live debut and shopped their demo around the country, eventually landing a deal with an indie record label, TVT Records.
Following the record deal, Reznor went back into the studio to polish up the demo tape in what became the band’s debut album, Pretty Hate Machine. The album received moderate commercial success and helped them establish a cult following that maintained consistent sales.
For the band’s sophomore album, Nine Inch Nails packed up and moved to a studio in Los Angeles called Le Pig, the same house where actress Sharon Tate was murdered during the Charles Manson murders.
The band’s second project is a concept album focused on a protagonist as he descends into self-destruction and madness. The album, The Downward Spiral is considered to be the band’s breakout project and is one of the primary examples of industrial rock breaking into the mainstream. After the success of the album, the band set out on the Self Destruct tour.
“On that tour, I was a mess, quite honestly. This was the peak of Nine Inch Nails’ newfound rocket ship of fame,” Reznor said in an old Rolling Stone interview. “It distorted my personality and became overwhelming: to deal with having everyone treat you different, to going from not being able to afford a gas bill to show up to arenas full of people who kind of think they know you. The line starts to blur between the guy onstage and the person you used to be.”
The Self Destruct tour is when Reznor’s substance abuse and mental health issues began to take hold. Reznor struggled to deal with the fame that the band had acquired so quickly and wasn’t sure how to respond. To deal with the problems that he was going through, Reznor turned to alcohol and cocaine.
“I look back to who I was 20 years ago, and I wasn’t equipped to deal with any sort of the weirdness of fame. Alcohol, drugs and what not became a tool to help cope and did for a while until they didn’t,” Reznor told the Rolling Stone.
Reznor said that during the Downward Spiral era, he thought that putting all he had into his music would be the cathartic and emotional experience he needed to look past all that was going on at this time.
“Downward Spiral felt like I had an unending bottomless pit of rage and self-loathing inside me, and I had to somehow challenge something, or I’d explode,” Reznor told The Guardian in 2013. “I thought I could get through by putting everything into my music, standing in front of an audience and screaming emotions at them from my guts … but after a while it didn’t sustain itself, and other things took over – drugs and alcohol.”
Despite the problems he was facing, Reznor carried on. While Nine Inch Nails entered a period of hibernation, Reznor focused on aspects of music like producing for other artists such as Marilyn Manson and contributing songs to movies like David Lynch’s Lost Highway.
After five years of alcoholism, drug abuse and writer’s block, the band ended its hiatus and returned with their third album, The Fragile.
“The Fragile was an album based a lot in fear, because I was afraid as fuck about what was happening to me,” Reznor told Spin Magazine in 2005.
Reznor’s struggles with addiction continued until the end of The Fragile tour. He experienced an overdose in London on “China White” heroin that he mistook for cocaine.
“I was going to just drink myself or drug myself out of it. I got back to New Orleans after the Fragile tour, and I’d pretty much lost my soul. I just felt like nothing.”
After coming home from the tour, Reznor still did not seek out drug and alcohol rehab initially.
“Somebody telling me I had a drinking problem was not something I wanted to hear.”
But after some time passed, and Reznor experienced more tragedy in the death of a close friend and studio technician. Reznor entered a rehab facility in 2001, successfully completed it and has lived a sober life since.
Although, Reznor did say that getting sober was not an easy task.
“Incredibly unpleasant experience. Hardest thing I’ve ever done. But many benefits come from it, aside from not being dead. I sorted through a lot of shit that I was carrying around. I’m very grateful that I had to go through that,” he told Entertainment Weekly.
After going through rehab, Reznor had to confront his past while still remaining sober. He has said that while he doesn’t think the temptation to drink is too overwhelming, he’s going to play it safe and not test his luck.
“I prefer not to be an addict. And I prefer to have the 10 wasted years of my life back. But one good aspect when you do the work to get clean is that painful self-examination is involved in that,” he said according to NME.
After getting clean and feeling a tremendous amount of shame for the actions and missed opportunities of the past and the damage that he had caused, going through recovery ended up being the cathartic experience Reznor was searching for from the early years of his career.
By being free of alcohol and drugs, and not romanticizing them any longer, Reznor was able to use what he had learned about himself during this time and channel that energy into continuing to create the music he knew he was capable of.
Since going through recovery, Nine Inch Nails has seen a resurgence and Reznor himself has seen success in his creation of movie scores. He has helped create scores for a number of David Fincher films such as The Social Network, The Girl with the Dragon Tattoo and Gone Girl.
Reznor is a model of success for those looking to go through the rehabilitation process and become sober and live a clean, healthy lifestyle. If you feel like substance abuse may be taking control of your life, you should reach out today to enlist the help of a certified drug and alcohol rehabilitation centers.
Early in his career, Reznor met with David Bowie who ended up being a big reason that led to his sobriety. Giving him advice that has helped him throughout his life.
“[Bowie] said some things that weren’t scolding, but pieces of wisdom that stuck with me: ‘You know, there is a better way here, and it doesn’t have to end in despair or in death, in the bottom.’”
Choose Recovery Over Addiction
We're here 24/7 to help you get the care you need to live life on your terms, without drugs or alcohol. Talk to our recovery specialists today and learn about our integrated treatment programs. | <urn:uuid:fd957f4e-7c6e-40f2-acce-357898a84b4c> | CC-MAIN-2023-40 | https://landmarkrecovery.com/stories-of-recovery-trent-reznor/ | 2023-09-26T06:05:06Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.983857 | 1,851 |
“It’s kind of fun to do the impossible” ~walt disney
I am making room for the possibility of bliss. I am letting go of old constraints. I have reasoned that without opening up to the idea of bliss I would not be able to approach it.
So I am making room to be in bliss, to become blind to that which harnesses me to old ways of being. I have not come this far through the muck and I have not restoratively lain by the sidelines for these many long nights to not get up and get going now that I am just that – restored.
Coming to a conclusion. Concluding a completion. I must be walking through this inner door and hanging up my old hat. I am unencumbered without moss on my feet. I have groaned and growed up. My peace is in knowing that now is the time to move on.
Thank you for helping me see and be aware of these things for without this constant inner vision not much could manifest. And with this inner vision all things are possible!
Can you see inside yourself well enough…yet?
Tag. You’re It! | <urn:uuid:2587ecb9-db70-4ba4-b83a-1b584e027224> | CC-MAIN-2023-40 | https://lanichaves.com/2015/all-things-are-possible/ | 2023-09-26T05:42:36Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.961051 | 243 |
Available via Everybody Press
Exit signs on a seaside highway contemplates fragmented territory set against the backdrop of an ongoing apocalypse. The poems both acknowledge the raw violence created by borders, while stubbornly searching for glimpses of a better world that lies within reach. With language that is confrontational but also hopeful, it invites us to liberate ourselves from structures that are far more fragile than we believe them to be.
Subverting patriotism and place, Exit signs on a seaside highway invites us to plunge into the painful depths borders create. Atallah wants to know why we’re “in love with a place that chronically guts itself,” aware that there is “something delicious about [the] intensity” of that allegiance. Part ode, part obituary, part manual, Exit builds on its hard truths: “the scales are broken” and “history doesn’t repeat, patterns do.” But a tender reality continues to search for art in its healing. Atallah knows we can “easily weave an epic tale from the fragments left behind.” This is a stunning and necessary debut.
— Ghinwa Jawhari, author of BINT
A sensational debut collection. These poems brim with place: checkpoints, borderlands, untouched oceans, highways, airports, televised homelands. She captures both the exile’s longing and their rage, the paradox of returning to places you must inevitably leave again. This is the mark of a true memory-keeper, one who holds the echo of a place, a life, a history, for those who cannot. I stole dust, a promise, Atallah writes, a glance and carried them across lands. We, too, travel the lands through these luminous poems. It is an honest journey, one I’m grateful to Atallah for leading.
— Hala Alyan, author of The Arsonists’ City
︎Lara Atallah’s Exit signs on a seaside highway, from its unforgettable opening poem, is interested in conjuring many worlds: parallel universes where the sun is “a god gifting infinity,” a Parisian night wherein the speaker “kills many selves in cold blood,” a Beirut whose “dead walk amongst the living,” who “dances to an apocalypse dressed like spring.” Through a lyricism carrying multiverses of historical weight, we’re reminded that “life is what happens when you graze infinity.” Here are poems which flow through formal and imagistic registers in conversation with the likes of Etel Adnan and Dunya Mikhail. I am so grateful to be alive and writing at the same time as Lara Atallah. This book is a multiverse in every sense.
— George Abraham, author of Birthright
** Available through Everybody Press. Link to purchase | <urn:uuid:0a4a1fdb-3ef1-4a8a-b845-7b714d7fa633> | CC-MAIN-2023-40 | https://lara-atallah.com/Exit-signs-on-a-seaside-highway | 2023-09-26T06:43:56Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.930989 | 602 |
Hovering prices of meals, energy and tons of essentials are pushing many UK households to the brink as the winter months approach.
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Within the predominant of a series of films: ‘Families on the Frontline’, Newsnight frolicked with two households to peep how the squeeze is being felt by them.
One mother, Kat, is now the usage of her native meals bank for the predominant time having beforehand donated to it within the previous. At dwelling meanwhile, her tv and wifi had been disconnected to have the ability to place on funds.
One more mother, Sanaa, who has her seventh runt one on the approach, is feeling the stress on the family purse as the charge of meals and clothing increases.
#Newsnight #BBCNews #BBC
Newsnight is the BBC’s flagship news and most modern affairs TV programme – with analysis, debate, exclusives, and sturdy interviews.
Web web negate online: | <urn:uuid:0348c110-b2ca-44b1-bb85-96fbbbc06bd9> | CC-MAIN-2023-40 | https://laramie-advantage.com/ive-purchased-nothing-left-to-promote-households-coping-with-the-fee-of-residing-squeeze-bbc-newsnight/ | 2023-09-26T06:26:28Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.95402 | 210 |
The Forest Lawn empire began in 1906 when its forgotten first founder John B. Treadwell established its flagship Glendale cemetery. The company became “Forest Lawn Memorial Park” in 1917 under the leadership of newcomer Hubert Lewright Eaton (1881-1966), who Forest Lawn still considers its true founder. One of Eaton’s partners was wealthy realtor William Irving Hollingsworth (1862-1937), who also owned the property that would eventually become Forest Lawn Hollywood Hills. In 1926, Hollingsworth allowed the City of L.A. to lay a highway through said property. First called Riverside Drive South, it was rechristened Hollingsworth Drive in 1941. Forest Lawn acquired the land by 1946; after years of protests (led by Van M. Griffith, son of Griffith Park‘s benefactor), the company was finally allowed to build their graveyard here in 1950, which is when Hollingsworth Drive was renamed Forest Lawn Drive. Forest Lawn Hollywood Hills officially opened in 1952. | <urn:uuid:51cfabd7-f91e-4e35-96a7-91822d797af6> | CC-MAIN-2023-40 | https://lastreetnames.com/street/forest-lawn-drive/ | 2023-09-26T06:17:41Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.966372 | 205 |
In recent years, non-alcoholic beverages have become more mainstream as people shift their focus to moderation and health. Due to this shift, there’s been an increase in demand for quality non-alcoholic beverages.
Pauline Idogho saw this demand and decided to create her own line of ready-to-drink non-alcoholic cocktails, Mocktail Club. Inspired by her global travels and quest to find healthy and enjoyable alternatives to alcohol, she began creating bold and daring flavors that are typically not found in non-alcoholic beverages.
“I am originally from Nigeria and grew up in London – then moved to the US for college. As a result, I loved to travel and worked in the Middle East, Africa and Asia. All the different cultural experiences have shaped me and ended up being the springboard for a lot of the cocktail flavors,” said Pauline.
Pauline came up with the concept for Mocktail Club when she was expecting and wanted healthy and sophisticated non-alcoholic options and found a limited selection. She decided to fill that gap in the market herself and began testing the idea among a focus group of moms during her maternity leave.
By November 2018, Pauline had launched her business and started selling her non-alcoholic beverages at Whole Foods in the Mid-Atlantic and in food services. She faced challenges early on, having to convince retailers that there was indeed a need for non-alcoholic options in their stores and menus.
“Performance of the products and creating more revenues by upselling customers who had only soda or water to choose from was an easy way to convince them to keep us on their menus and stores.”
What had started as a small passion project has since evolved into something significant, with a global impact.
Mocktail Club is a mindful, health-focused company and a great option for anyone looking to reduce their alcohol intake and really focus on balance and mindfulness. Mocktail Club beverages are also full of superfruits and prebiotics, providing functional health benefits with each drink.
Additionally, Mocktail Club is a mission-driven company, prioritizing sustainability with its packaging and production to reduce their footprint and supporting clean water access globally with 1% of all sales going to Water For People, a global charity that provides free and clean drinking water across the world.
Pauline is also a founding member and head of the finance committee of the Adult Non-Alcoholic Beverage Association, which works to promote inclusivity among individuals who have ever felt left out because of their drinking preferences.
Paving the way for other aspiring BIPOC entrepreneurs
Mocktail Club’s impact doesn’t stop there. Founded by a woman of color, the company is also focused on promoting diversity and inclusion.
“I feel it is a strength to have diverse voices with different job experiences and cultural backgrounds,” said Pauline. “We have a very small team that have origins from Nigeria, Argentina and Vietnam. We are the faces of a diverse customer base, which makes us richer as a company. We are excited to build a national brand led by BIPOC women.”
Currently, less 2% of women get venture capital money and less than 100 black women have raised a million dollars in the US in 2022. Pauline is defying those odds and paving the way for other women of color in her industry.
“I love the fact that my 3 year old and 5 year old can easily recognize the Mocktail Club brand and associate with me. As a result, I feel their world will be limitless because they will grow up seeing me building an idea into fruition from scratch,” she said. “I am excited to build an iconic brand that can motivate more women of color to dream big and make it happen.”
Pauline believes in paying it forward to other aspiring BIPOC and female entrepreneurs by supporting them and sharing lessons learned to help improve the underrepresentation of minority groups in the highest levels of corporations.
You might be interested: Dr. Angela Zeng’s Karuna empowering consumers to make better choices for happier, healthier lives
For anyone thinking of becoming an entrepreneur, Pauline advises you start with an idea that you’re passionate about and that you believe needs to exist. “Then, test it, work hard and find ways to validate and iterate your concept,” said Pauline.
Once you have that concept, “surround yourself with strong mentors and advisors and also with a supportive family or friend base,” she continued. And finally, “lean into yourself and believe in your capabilities so that when you face obstacles and rejections, you can continue to find your North Star. Stay tenacious and learn from adversity—which is a good pathway to success.” | <urn:uuid:c760f50f-a02e-4cc9-8721-4b303922d846> | CC-MAIN-2023-40 | https://latinasinbusiness.us/2022/02/23/meet-mocktail-club-the-non-alcoholic-beverages-brand-thats-making-a-global-impact/ | 2023-09-26T06:24:37Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.969046 | 997 |
The Mills Headpiece features ribbon folding techniques. It provides an edging approach to a classic style. This style is one size fits all and is secured to the head using a series of elastic loops.
This style is perfect for many occasions select your cream Mills Headpiece today.
This style can also be made in a selection of other colours. Contact us to find out more about customising this style. Please allow 2-4 weeks lead time for customisation.
Each piece by Lauren J Ritchie is handmade in the Melbourne based studio. Designs can be shipped across the globe. | <urn:uuid:ed8d3c9e-6145-4410-abf6-fcf5650770ea> | CC-MAIN-2023-40 | https://laurenjritchie.com/products/mills-headpiece | 2023-09-26T06:03:33Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.922164 | 128 |
Catholic News Agency picked up Fulton’s Story. Big thanks to Matt Hadro for picking it up. We need all the prayers we can get. Our hope is to storm heaven for a miracle for baby Fulton. Either way we are confident God’s miracles happen in ways we do not always understand. Perhaps Fulton’s story will help others. God Bless everyone!
Here is a link to the Catholic News Agency piece: https://www.catholicnewsagency.com/news/this-catholic-family-is-asking-fulton-sheens-intercession-for-a-second-miracle-67538 | <urn:uuid:a941f937-df6f-4859-be10-c16f3a44e826> | CC-MAIN-2023-40 | https://lawlife.org/catholic-news-agency-picks-up-fultons-story/ | 2023-09-26T06:28:14Z | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510149.21/warc/CC-MAIN-20230926043538-20230926073538-00498.warc.gz | en | 0.831864 | 135 |
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