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Rett syndrome genetics {#Sec1}
======================
It is now 50 years since Andreas Rett reported his observations on 22 girls with similar clinical features, subsequently known as Rett syndrome (RTT). Classic RTT is defined by a regression phase and subsequent stabilization of diagnostic criteria, which include pa... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-nutrients-09-01369}
===============
Recently, a lot of studies have focused on pro-health and curative properties of natural products, including bee products, and bee pollen is among these valuable apitherapeutics. It is a product of plant origin, collected and partly processed by bees. It is pr... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Because nurses care for their patients around the clock in hospitals, they see themselves as primarily responsible for their patient's well-being and the main role they play in the health care team is to serve as a key guardian of patient safety. However, injuries in health care today a... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Psychosis, principally including schizophrenia, is a severe pathological condition that commonly develops in one's twenties and often leads to a chronic course. Individuals with schizophrenia may experience years of disability, which also imposes a considerable burden on their family care... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Oral squamous cell carcinoma (OSCC) is the sixth most common tumor in the world.\[[@ref1]\] There are several strategies for OSCC treatments involving chemotherapy, surgery, radiation, or a combination of these methods. However, the adequate understanding of cell biology of oral onc... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
The functionally distinct repertoire of secreted cytokines of type 1 and type 2 CD4^+^ T helper cells (Th1 and Th2 cells) has been shown to play an important role in the pathogenesis of human allergy and inflammatory diseases \[[@B1]\]. Effector Th1 cells secrete predominantly interferon-γ (IFN-γ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Fatigue is a common symptom in stroke \[[@B1],[@B2]\]. It can be considered to be 'a feeling of early exhaustion, weariness and aversion to effort' \[[@B3]\], or a 'lack of energy with an increased need to rest' \[[@B4]\]. The extent of fatigue has been shown to increase with stroke severity\... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
> Try not to become a man of success, but rather try to become a man of value.
>
> --Albert Einstein
Few dermatologic problems carry as much emotional overtones as the complaint of hair loss, especially in the female patient. Adding to the patient\'s worry may be prior frustrating ... | {
"pile_set_name": "PubMed Central"
} |
The role of microbes during the DWH oil spill {#s1}
=============================================
The DWH oil rig exploded in the Gulf of Mexico in April 2010. The spill lasted for approximately 84 d, which was recorded the largest oil spill in United States to date (Crone and Tolstoy, [@B22]). The accident yielded an... | {
"pile_set_name": "PubMed Central"
} |
Array-CGH data have been deposited in NCBI's Gene Expression Omnibus (GEO accession number GSE63216; <http://www.ncbi.nlm.nih.gov/geo>).
Introduction {#sec005}
============
Cancer is caused by genomic aberrations that drive tumor initiation and progression. Oncogene activation and tumor suppressor gene inactivation c... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Head and neck malignancy and its treatment might adversly influence the patient\'s activities of daily living These patients have issues with regards to speech capacity, sustenance, and appearance (Deleyiannis, et al, 1997, Gellrich, et al, 2002).\[[@ref1][@ref2]\]
Longitudinal inf... | {
"pile_set_name": "PubMed Central"
} |
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1. Introduction {#sec1-materials-10-01167}
===============
The Mg-Li alloy possesses many impressive advantages, such as a low density, high specific elastic modulus, high specific strength, good electromagnetic shielding, and damping property \[[@B1-materials-10-01167],[@B2-materials-10-01167],[@B3-materials-10-01167... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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"pile_set_name": "PubMed Central"
} |
The authors confirm that all data underlying the findings are fully available without restriction. All relevant data are within the paper and its Supporting Information files.
Introduction {#s1}
============
While gastric cancer is the fourth most common cancer in the world, it is the second leading cause of death. [... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Children with developmental coordination disorder (DCD) have significant difficulty in acquiring and executing the essential, coordinated motor skills involved in self-care (e.g., dressing), recreational activities (e.g., ball skills), and academic performance (e.g., handwriting) comp... | {
"pile_set_name": "PubMed Central"
} |
Pembrolizumab is a monoclonal antibody against the programmed cell death 1 (PD-1) receptor, and is widely used for the treatment of various malignancies, most commonly malignant melanoma. Here we report the first documented case of Organizing Pneumonia complicating treatment with Pembrolizumab.
1. Case report {#sec1}
... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec0005}
===============
Medicinal plants have been used in the prevention and cure of various diseases based on traditional knowledge for a long time. These plants are often considered safe because of the absence of adverse events. However, many of these plants have not been subjected to toxicologic... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Maternal death is defined as death during pregnancy or up to 42 days after termination of pregnancy, irrespective of the duration and site of pregnancy, resulting from any relevant cause or as a result of care provided during pregnancy, excluding accidental death as a cause. The mat... | {
"pile_set_name": "PubMed Central"
} |
See related research article <http://arthritis-research.com/content/7/5/R1063>
In daily clinical practice, the Disease Activity Score using 28 joint counts (DAS28) is used to monitor the disease activity of rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs (DMARDs) and biological agents... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the manuscript.
Introduction {#sec004}
============
Dengue virus (DENV), an enveloped virus with a single-stranded, positive sense RNA genome, belongs to the genus flavivirus and comprises mainly four serotypes (DENV-1, -2, -3, and -4). DENV infection causes a wide range of clinical signs... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
Over the last 10 years, concern has been mounting over rapid rises in the prevalence of non-communicable diseases (NCDs) in the global South and the health and economic burden they represent. This has been driven, in part, by the World Health Organisation (WHO) which has publis... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec005}
============
Natural and man-made disasters are common worldwide. Various disasters have occurred in South Korea in the twenty-first century, such as typhoons, floods, and subway fires. Among them is the sinking of the... | {
"pile_set_name": "PubMed Central"
} |
Cronin EM, Bogun FM, Maury P, et al. 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias: Executive summary. J Arrhythmia. 2020;36:1--58. 10.1002/joa3.12264
\[Correction added on 22 January 2020, after first online publication: typographical errors have been amended on ... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
In 2015, 303,000 maternal deaths were reported globally, of which 99% occurred in developing countries. About 60% of this global smaternal mortality burden is shared by only ten countries including India, Nigeria, Afghanistan, Ethiopia, Democratic Republic of the Congo, Tanzania, Kenya, U... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Sexual violence against children is a major public health problem in its own right, and it is directly and indirectly relevant to the HIV epidemic. The physical trauma of sexual violence can increase the risk of HIV transmission directly[@b1; @b2; @b3] and the psychological damage related to ... | {
"pile_set_name": "PubMed Central"
} |
Main text {#Sec1}
=========
Central giant cell granuloma (CGCG) is defined by the World Health Organization as an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of haemorrhage, aggregations of multiple nucleated giant cells, and occasionally trabeculae of woven bone \[[@CR1]\].
... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .151}
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"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-cancers-11-00163}
===============
Animal models have been extensively used in cancer research to investigate biology and genetics of human malignancies, including breast cancer, as well as efficacy and toxicity of chemical and biological agents \[[@B1-cancers-11-00163]\]. After the recent advent... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Esophageal cancer, which originates in the esophageal mucosal epithelium, is characterized by strong invasiveness and high mortality \[[@b1-medscimonit-22-2195]\]. Approximately, 300 000 people die from esophageal cancer in the world annually \[[@b2-medscimonit-22-2195]\]. There is significant va... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Strict maritime quarantine (with facility quarantine on land in some cases), appeared to effectively prevent the entry of the 1918--19 influenza pandemic into American Samoa and delayed its entry into mainland Australia, Tasmania and New Caledonia \[[@B1]\]. Quarantine measures during this pandem... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Lipopolysaccharide (LPS), an essential component of the surface of Gram-negative bacteria \[[@r1]\], has potent proinflammatory properties in many cell types \[[@r2]-[@r4]\], including endothelial cells \[[@r5],[@r6]\]. A major consequence of the LPS action on endothelial cells is the upregul... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
A steady increase in the incidence rate of thyroid cancer has been noted in recent decades all over the world, and the causes of this increase are still controversial. Thyroid cancer is the most common endocrine malignancy (1.0--1.5% of all newly diagnosed cancers in the United States of ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
OA is a common joint problem affecting older adults in Western populations \[[@B1]\]. Individuals with hand OA report significant pain and disability in their everyday life and consider hand OA to be a serious condition \[[@B2]\]. It has been suggested that OA in the thumb joints may represen... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-18-01336}
===============
According to a 2014 United States Census Bureau report, the population aged 65 and over has been projected to grow from 43.1 million in 2012 to 83.7 million in 2050 \[[@B1-sensors-18-01336]\]. One of the distinctive health states related to the aging process is ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
microRNAs (miRNAs) constitute a new class of small noncoding RNAs that control post-transcriptionally the expression of gene products, either modulating directly protein translation or regulating the stability of messenger RNA. There is increasing evidence of the role that miRNAs play in regu... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Linear growth retardation or low height-for-age, commonly known as stunting is a useful anthropometric measure for children in terms of its positive correlation with social and economic deprivation. Stunting is now acknowledged as the best proxy measure for child health inequalities \[[@B1],[@B2]... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Let $\documentclass[12pt]{minimal}
\usepackage{amsmath}
\usepackage{wasysym}
\usepackage{amsfonts}
\usepackage{amssymb}
\usepackage{amsbsy}
\usepackage{mathrsfs}
\usepack... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Cervical cancer is the second most common type of cancer among women in Brazil ([@b1-cln_68p809],[@b2-cln_68p809]), and in 2012, it was estimated that 17,540 new cases of cervical cancer would occur in Brazil (approximately 17 cases in every 100,000 women) ([@b3-cln_68p809]). Human papilloma ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Snake venoms are complex mixtures of enzymatic and non enzymatic proteins, together with other components such as carbohydrates, lipids, nucleosides and metals. These function together to immobilize, kill and digest the prey [@pone.0021532-Aird1] `.` Snake venoms have various envenomati... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
When a target is presented with distractors in a search array, the distractors are often processed to some extent along with the target, resulting in increased response latencies when the target and distractors indicate different responses compared with when they indicate the same respo... | {
"pile_set_name": "PubMed Central"
} |
Despite dramatic improvements in the hardware resources and computational power available to pharmaceutical researchers over the past few decades, the methods used for assessing the 2D chemical similarity between two molecules hasn\'t changed much since the 1960s. Here we report a novel chemical database search method ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Obesity has dramatically increased during the past decades and has now reached epidemic proportions in both developed and developing countries. Even in Japan where the self-reported prevalence of obesity has remained consistently low over the last 30 years, obesity is now increasing in middle... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Disability is a public health priority \[[@CR1]\]. The level of disability is inversely associated with socioeconomic position \[[@CR2]\]. Musculoskeletal (MSK) diseases are the most common cause of disability worldwide \[[@CR3]\] and their disabling effects are more severe in develop... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
With the rapid aging of the global population, the prevalence of chronic diseases such as diabetes and cardiovascular disease is increasing every year \[[@pone.0151336.ref001]--[@pone.0151336.ref003]\] and... | {
"pile_set_name": "PubMed Central"
} |
According to the WHO report *Global atlas on cardiovascular disease prevention and control*, cardiovascular diseases are the leading causes of death and disability in the world. Heart failure is a very common condition that is costly, disabling, and potentially deadly. In developed countries, around 2% of adults suffer... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Alzheimer disease (AD) is a late onset neurodegenerative disorder characterized by progressive neuronal loss, especially in the cortex and the hippocampus ([@b30]). The vast majority of AD is sporadic (SAD), but mutations in the amyloid precursor protein (APP) and in presenilin-1 (PS1) and -2... | {
"pile_set_name": "PubMed Central"
} |
(J Am Heart Assoc. 2016;5:e003846 doi: [10.1161/JAHA.116.003846](10.1161/JAHA.116.003846))
Introduction {#jah31902-sec-0004}
============
A large proportion of myocardial infarctions (MIs) are unrecognized,[1](#jah31902-bib-0001){ref-type="ref"}, [2](#jah31902-bib-0002){ref-type="ref"}, [3](#jah31902-bib-0003){ref-ty... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Talus fractures are rare yet serious fractures that usually necessitate operative intervention with a relatively high risk of complications \[[@CR1]\].
Peroneal tendon dislocation is a commonly missed soft tissue injury which may have a significant impact on the outcomes. Available l... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Lung cancer is a major cause of morbidity and mortality worldwide and the most common cause of cancer-related death ([@b1-or-34-06-2871]). Non-small cell lung cancer (NSCLC) accounts for \~85% of all lung cancers. Although surgical and chemotherapeutic treatments have made great contributions... | {
"pile_set_name": "PubMed Central"
} |
Erratum to: J Orthopaed Traumatol DOI 10.1007/s10195-014-0292-0 {#Sec1}
===============================================================
The author would like to correct the following error in the publication of the original article:
In the discussion section, eighth sentence of the first paragraph should read as:
"I... | {
"pile_set_name": "PubMed Central"
} |
Executive Editors
=================
*Senior Editors*: K.R.Fox, *Southampton, UK*; foxnar\@soton.ac.uk B. Stoddard, *Seattle, WA, USA*; stoddnar\@fhcrc.org
M.Madan Babu, *Cambridge, UK*D.Corey, *Dallas, TX, USA*M.Wegner, *Erlangen, Germany*<narlmb@mrc-lmb.cam.ac.uk><david.corey@utsouthwestern.edu><... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Ulcerative colitis (UC) is a chronic, relapsing, and remitting inflammation of the large intestine \[[@B1]\]. It often starts at young age and lasts throughout life. Debilitating symptoms, such as increased frequency of bloody stools, pain, fever, and lack of effective treatment... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
The anterior clinoid process (ACP) is the apex portion of the lesser wing of the sphenoid bone. ACP\'s anatomical location is important for its relation with neighboring structures including optic nerves, internal carotid artery (ICA), and other neurovascular structures.[@B7] Anterior clinoid... | {
"pile_set_name": "PubMed Central"
} |
Nanoparticles are of advantages of unique optical, electrical and chemical properties, and have been used for protein and nucleic acid analysis, biosensors, biochips and nanocatalytic analysis[@b1][@b2][@b3][@b4][@b5][@b6][@b7][@b8]. Noble metal nanoparticles have high electron density, good biocompatibility, good cata... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Population health can be viewed as a complex and dynamical system in which the patterns of health and disease exist, persist, and change over geography and time. \[[@B1],[@B2]\] The underlying patterns of exposure that influence health status are the non-random result of interactions between the ... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Scientific background {#Sec2}
---------------------
Cognitive health has been consistently quoted as significant for life quality by older people and is regarded as an important contributor to late-life functioning \[[@CR1], [@CR2]\]. Patterns of cognitive change show great variation in ... | {
"pile_set_name": "PubMed Central"
} |
Abbreviations {#nomen0010}
=============
1-OHP
: 1-Hydroxypyrene
2-AN
: 2-Aminonaphthalene
3-HPMA
: 3-Hydroxypropylmercapturic acid
4-ABP
: 4-Aminobiphenyl
6MWT
: Six Minute Walk Tests
AE
: Adverse Event
Ae24h
: Amount excreted over 24 Hours
AIx
: Augmentation Index
BoE
: Biomarker o... | {
"pile_set_name": "PubMed Central"
} |
{.149}
{.150}
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"pile_set_name": "PubMed Central"
} |
Background
==========
The development of a fistula between the tracheobronchial tree and the gastric conduit post esophagectomy is a rare and often fatal complication. Most fistulae occur from direct communication between a dehisced anastomosis and adjacent bronchus. Anastomotic leaks are responsible for approximately... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-proteomes-06-00051}
===============
Novel methods for proteomic analysis of biological tissues have developed rapidly in the past decade; however, neuroproteomics remains a challenging field of study. The mammalian central nervous system (CNS) is far different from any other organ in the mammali... | {
"pile_set_name": "PubMed Central"
} |
###### Strengths and limitations of this study
- The study shows that weather variation could be captured even in a single seasonal transition.
- After factoring in weather variation, the study establishes an association between urban design and the likelihood of children accumulating globally recommended levels ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec0005}
============
The COVID-19 pandemic exposes the entire medical team and, mainly, anesthesiologists, to a major risk of infection. As we are dealing with a potentially high severity disease, especially to the population at risk, due to the high risk of infection and transmission to others during ... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Respiratory allergies, particularly allergic rhinitis, are among the most common allergies within various populations all over the world and the incidence is expected to increase \[[@B1]\]. Prevalence of respiratory allergy has been determined between 10-30% in different studies \[[@B2]-[@B5]\].
... | {
"pile_set_name": "PubMed Central"
} |
1.. INTRODUCTION
================
"CVI is characterized by sudden neurological dysfunction resulting from insufficient blood supply to brain tissue. Stroke can be divided into two groups depending on the etiology: ischemic (83%) and hemorrhagic (17%)" ([@R1]). "Thrombosis is a blood clot that obstructs a blood vessel ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
============
Brachial plexus tumor is recognized as a very rare clinical problem. Benign tumors include schwannoma and neurofibroma, whereas malignant tumors include malignant schwannoma, fibrosarcoma, neuroblastoma, as well as metastatic tumors of plexus, such as lymphoma, leukemia, lung cancer... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s1}
===============
The growth of older population around the world in the last few decades has caused an increase in problems which can be associated to deteriorated mechanical properties of bone; osteoporosis is the clearest example of one such condition.
Computer models have been extensively empl... | {
"pile_set_name": "PubMed Central"
} |
Clinical Case Reports 2017; 5(11): 1785--1788
Introduction {#ccr31184-sec-0001}
============
The *GJB2* gene encodes the connexin 26 (CX26) protein, which is a major structural component of gap junction channels between cells, and plays a vital role in hearing physiology [1](#ccr31184-bib-0001){ref-type="ref"}. To da... | {
"pile_set_name": "PubMed Central"
} |
Dejun Yu (Te-tsun Yu, Feb. 1, 1908--July 14, 1986) was a famous plant taxonomist and horticulturist in China as well as an expert on botanical gardens (Fig. [1](#Fig1){ref-type="fig"}). As a patriotic scientist, Dejun Yu refused a position in Britain and returned to China without hesitation in 1950. He devoted his whol... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Acute kidney injury (AKI) occurring in the setting of intensive care medicine (ICU) complicates the clinical course of approximately 40% of ICU patients \[[@SFS070C1], [@SFS070C2]\]. Its incidence is rising due to more aggressive diagnostic and therapeutic interventions in an ageing pop... | {
"pile_set_name": "PubMed Central"
} |
FDA Status: Not Cleared
**Summary:** Cartilage defects are frequently present in patients with FAI. Several arthroscopic treatment options are available including MFx and AMIC. In the present study tha AMIC technique using a collagen type I/III bilayer matrix (Chondro-Gide®) is having advantages in maintaining clinica... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
The Effort-Reward Imbalance (ERI) model, a recent model of occupational stress, focuses on a negative trade-off between experienced \'costs\' and \'gains\' at work. In this model, high ratio of occupational effort spent relative to rewards received in turn in terms of money, esteem, job security,... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
============
Loss of permanent teeth among humans is always implicated in progression of dental caries and periodontal diseases in the surrounding teeth. Furthermore, tooth loss can effect individual\'s psychological, social, and physical impairment thereby declining the quality of life.\[[@ref1... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
The adverse cardiovascular and vasculotoxic effects of long-term exposure to high levels of inorganic arsenic in drinking water have been well characterized \[[@CR1]\]. Recent studies have demonstrated an increased risk of cardiovascular disease (CVD), ischemic heart disease (IHD) and mor... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1}
============
Spontaneous subcapsular or perinephric haemorrhage is a relatively uncommon but diagnostically challenging condition. In the evaluation of this condition, the differential diagnosis includes renal tumours, vascular disorders and pyelonephritis. While computed tomography would readily ... | {
"pile_set_name": "PubMed Central"
} |
Correction to: *Scientific Reports* 10.1038/s41598-017-18236-7, published online 20 December 2017
The original version of this Article contained an error in the Abstract.
"Over 200 mutations in 60 different genes have been shown to cause RP."
now reads:
"Many mutations in 60 different genes have been shown to cause... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .1}
{#sp2 .2}
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{#s... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Hypertension is highly prevalent globally. In 2005, the global burden of hypertension was estimated to rise from nearly 1 billion in the year 2000 to 1.6 billion in 2025 \[[@B1]\]. By 2010, the global burden of hypertension was estimated at about 1.4 billion, and this will poten... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-19-00293}
===============
The security and safety aspects of global navigation satellite systems (GNSSs) have been receiving significant attention from researchers and the general public, because the use of GNSSs has been increasing in modern society \[[@B1-sensors-19-00293]\]. Because t... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Cutaneous neoplasms with two or more distinct cell populations are rare but well documented, and may pose a diagnostic challenge to clinicians and pathologists. They often mimic other cutaneous tumors or present as nonspecific neoplasms. Diagnosis of a collision tumor may be an accidental and... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S1}
============
Sleep disorder is associated with various diseases' development and progression, such as obesity, type II diabetes ([@B29]) and cardiovascular diseases ([@B22]). Insomnia is the most prevalent sleep disorder, including sleep apnea, restless legs syndrome (RLS) and narcolepsy, and affect... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Mendelian randomisation (MR) is now widely used to infer the causal influence of one trait (the exposure) on another (the outcome)^[@CR1],[@CR2]^. It generally uses genetic instruments for an exposure, obtained from genome-wide association studies (GWAS). If the instruments are valid,... | {
"pile_set_name": "PubMed Central"
} |
Most pancreatic tumors are primary, and the majority are adenocarcinomas of ductal origin \[[@b1-jptm-2020-03-04],[@b2-jptm-2020-03-04]\]. Although direct invasion of the pancreas by adjacent aggressive tumors is often observed, pancreatic metastasis from distant primary sites is very rare \[[@b1-jptm-2020-03-04],[@b3-... | {
"pile_set_name": "PubMed Central"
} |
Dolly, Polly, and friends proved that somatic cells are potentially totipotent, but the reprogramming that a somatic cell nucleus must undergo during cloning remains an error-prone black box. James Byrne, John Gurdon, and colleagues (University of Cambridge, UK) have now shown that the biochemically tractable frog oocy... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The articles in this Special Topic cover a range of issues concerning long-distance projecting cortical GABAergic neurons, in the context of interneuron diversity. As several authors report, these neurons are attracting renewed attention spurred by new techniques and markers which show great ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Although gastric cancer has been decreasing in terms of both incidence and mortality in most developed countries in recent decades, it still causes substantial disease burden \[[@B1]\]. Over 90% of people with early stage gastric cancer survive for five years or longer after sur... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The cereal prolamins are broadly classified into cysteine (Cys)-poor and Cys-rich species ([@B33]). In wheat and barley, most prolamins are Cys-rich species (gliadins and glutenins in wheat and hordeins in barley) and are deposited in protein storage vacuoles (PSVs) in the form of very large ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Aging is associated with compromised function, impaired mobility, and loss of independence, resulting in decreased quality of life. Osteoporosis is characterized by decreased mineral mass and mechanical strength of bone leading to fragility fractures in the elderly. Vertebral fractures are on... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Parkinson\'s disease is a neurodegenerative disorder which affects approximately 1% population over the age of 60 \[[@B1]\]. The most motor symptoms of this disease are caused by dysfunction of the nigro-striatal pathway. DAergic neurons in the substantial nigral pars compacta (SNc) project axons... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Gastric cancer (GC) is the fifth most common malignancy and the third leading cause of cancer-related death worldwide, and the highest mortality rates are seen in East Asia, including China \[[@CR1], [@CR2]\]. Although overall survival has improved with the implementation of standard ... | {
"pile_set_name": "PubMed Central"
} |
**Session:** 51. Antimicrobial Stewardship: Interventions to Improve Outcomes
*Thursday, October 4, 2018: 12:30 PM*
| {
"pile_set_name": "PubMed Central"
} |
Background
==========
MicroRNAs (miRNAs) are short oligonucleotides (approximately 22 bp) that regulate gene expression. Target genes are determined by sequence complementarity between the 3\' untranslated region (UTR) and the mature miRNA, particularly in a 6 bp \'seed\' region \[[@B1],[@B2]\]. A range of algorithms ... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Neuroblastoma is a childhood tumor originating from the peripheral sympathetic nervous system. It is characterized of two different patterns of disease progress. One, frequently occurring in very young children and without amplification of the *MYCN*gene, is often associated with good prognosis a... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Competitive sports for disabled individuals have entered into a fast development process during the recent years. These sports have gained a place in a wide spectrum reaching open athletes and elite athletes. Paralympic games have raised awareness for the participation of disabled individuals... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Bluetongue (BT) is an infectious noncontagious viral disease of ruminants caused by the bluetongue virus (BTV). The virus, consisting of 24 different serotypes, is transmitted to its vertebrate host by a few species of biting midges of the *Culicoides* genus (*Diptera*: *Ceratopogonidae... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Aneurysms of the internal mammary artery (IMAA) are uncommon clinical entities \[[@RJU125C1]\] and usually occur in patients after sternotomy, placement of a central venous catheter or pacemaker leads \[[@RJU125C2]\]. Less common, these aneurysms are associated with vasculitis (e.g. Kaw... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-pharmaceutics-11-00020}
===============
According to the Joint United Nations Programme on HIV and AIDS (UNAIDS) factsheet from July 2018, between 31.1 and 43.9 million people currently live with HIV, although fewer than 23 million of them have access to antiretroviral therapy. 1.8 million peopl... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Within a species, organ size is remarkably reproducible. While extrinsic factors like hormones are required for growth, classic transplantation experiments indicate that intrinsic factors within organs determine size ([@bib7]). For example, embryonic limb buds transplanted from a large ... | {
"pile_set_name": "PubMed Central"
} |
Published: October 25, 2019
Introduction {#sec1}
============
In animal cells, cytokinesis leads to the separation of the cytoplasm into two daughter cells. Defects during this process can lead to polyploidy and aneuploidy, situations that are frequently observed in cancers ([@bib15]). Cytokinesis begins in anaphase ... | {
"pile_set_name": "PubMed Central"
} |
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