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13-cis-retinoic acid plus interferon-alpha: a phase II clinical study in squamous cell carcinoma of the lung and the head and neck. Retinoids and interferon-alpha (IFN-alpha) have been shown to have a synergetic antiproliferative and differentiative effect on many cell lines, and in combination they have already been t...
{ "pile_set_name": "PubMed Abstracts" }
Lack of correlation between the induction of donor class I and class II major histocompatibility complex antigens and graft rejection. The induction of donor major histocompatibility complex (MHC) antigens on nonrejected and rejected rat renal allografts was compared at various times after transplantation in two strain...
{ "pile_set_name": "PubMed Abstracts" }
A method for coronary artery calcium scoring using contrast-enhanced computed tomography. Limitations to the coronary calcium score include its requirement for noncontrast imaging and radiation exposure that approaches current methods for contrast-enhanced CT angiography. We sought to derive and validate a method of me...
{ "pile_set_name": "PubMed Abstracts" }
Isolation and preliminary characterization of a novel Helicobacter species from swine. To determine whether a Helicobacter sp similar to Helicobacter pylori in the stomachs of humans could be isolated from the stomachs of pigs. 4 young conventionally reared and 21 gnotobiotic pigs. Gastric mucosal homogenates (10% wt/v...
{ "pile_set_name": "PubMed Abstracts" }
Analysis of the domain structure of elongation factor-2 kinase by mutagenesis. A number of elongation factor-2 kinase (eEF-2K) mutants were constructed to investigate features of this kinase that may be important in its activity. Typical protein kinases possess a highly conserved lysine residue in subdomain II which fo...
{ "pile_set_name": "PubMed Abstracts" }
The outcomes of cementless total ankle arthroplasty - pilot study. Since new generation ankle endoprostheses came into common use, total ankle arthroplasty has become an alternative to arthrodesis in the treatment of advanced osteoarthritis. The aim of paper was present preliminary results of cementless total ankle art...
{ "pile_set_name": "PubMed Abstracts" }
Sublingual isosorbide dinitrate-stimulated tilt test for diagnosis of vasovagal syncope in children and adolescents. Vasovagal syncope is the most likely cause of syncope in the young. Head-up tilt-table test (HUT) provides the ability to provoke vasovagal syncope under controlled laboratory settings. In adult populati...
{ "pile_set_name": "PubMed Abstracts" }
Prostacyclin synthesis elicited by endothelin-1 in rat aorta is mediated by an ETA receptor via influx of calcium and is independent of protein kinase C. The purpose of this study was to characterize the receptor(s) and second messenger systems involved in prostacyclin (prostaglandin [PG] I2) synthesis elicited by endo...
{ "pile_set_name": "PubMed Abstracts" }
Silicone oil removal combined with macular pucker dissection: a retrospective review of 14 cases. Silicone oil must be removed from the eye to avoid late complications after the surgical management of proliferative vitreoretinopathy (PVR). Macular pucker, frequently observed after retinal detachment surgery, is respons...
{ "pile_set_name": "PubMed Abstracts" }
Short-term feeding of vitamin D3 improves color but does not change tenderness of pork-loin chops. The objective of this study was to determine the effect of short-term feeding of vitamin D3 (D3) on blood plasma calcium concentrations and meat quality of pork-loin chops. Three experiments were carried out to meet this ...
{ "pile_set_name": "PubMed Abstracts" }
Altered bile acid metabolism in primary biliary cirrhosis. Selected aspects of bile acid metabolism were assessed in six women with primary biliary cirrhosis and varying degrees of cholestasis. Urinary bile acid excretion was markedly increased and correlated highly with serum levels. In three patients in whom urinary ...
{ "pile_set_name": "PubMed Abstracts" }
Role of atrial peptide in the acute natriuretic response to uninephrectomy. Unilateral nephrectomy (UNX) is associated with an immediate natriuretic response of the remaining kidney. The role of atrial natriuretic peptide (ANP), as assessed by right atrial appendectomy (APX), was investigated in euvolemic anaesthetized...
{ "pile_set_name": "PubMed Abstracts" }
Infantile wheeze: rethinking dogma. Wheeze is a common symptom in young children and is usually associated with viral illnesses. It is a major source of morbidity and is responsible for a high consumption of healthcare and economic resources worldwide. A few children have a condition resembling classical asthma. Rarer ...
{ "pile_set_name": "PubMed Abstracts" }
Influence of some dopaminergic agents on antinociception produced by quinine in mice. 1. The analgesic effect of quinine and the influence of some dopaminergic agents on it were studied in mice. 2. Quinine (25-130mg/kg, ip) effectively elicited antinociceptive effect in a dose related manner. 3. D-Amphetamine (2.5-4mg/...
{ "pile_set_name": "PubMed Abstracts" }
A histochemical study of alkaline and acid phosphatase activity in osteoarthritic synovial membrane. In order to determine the localization and activity of alkaline and acid phosphatase in the synovial membrane of osteoarthritic hip joints, enzymo-histochemical analyses were performed using Burstone's and Barka & Ander...
{ "pile_set_name": "PubMed Abstracts" }
Isolation of a mycoplasma from three patients with lepromatous leprosy. Using a modified cell-free culture medium and modern microscopic equipment, a mycoplasma was isolated from scrapings of skin lesions of three patients with lepromatous leprosy. Three specimens were taken from the first patients. All five isolates w...
{ "pile_set_name": "PubMed Abstracts" }
Bradykinin-mediated hypotension after infusion of plasma-protein fraction. In patients who required volume expansion during extracorporeal circulation, the plasma bradykinin concentration was monitored simultaneously with the mean arterial pressure during infusion of either albumin solution or PPF. The PKA content of t...
{ "pile_set_name": "PubMed Abstracts" }
Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy. The major pathologic markers of prognosis in colorectal cancer include vascular invasion by tumor cells, invasion of adjacent lymph nodes, and perforation of the serosal wall. Recent work suggests th...
{ "pile_set_name": "PubMed Abstracts" }
Structural and functional properties of proteasomes purified from the human kidney. Proteasomes are 'proteolytic machineries' implicated in many cellular functions, including protein turnover, inflammatory response and immunosurveillance. They exist in various forms sharing the same catalytic core - the 20S proteasome....
{ "pile_set_name": "PubMed Abstracts" }
Effective flow performances and dialysis doses delivered with permanent catheters: a 24-month comparative study of permanent catheters versus arterio-venous vascular accesses. Permanent venous catheters have emerged as a long-term vascular access option for renal replacement therapy in end-stage renal disease patients....
{ "pile_set_name": "PubMed Abstracts" }
A family epidemiological model: a practice and research concept for family medicine. Drawing on knowledge from various behavioral science disciplines and epidemiology, a conceptual model for use in practice, education, and research in family medicine has been developed. This model uses three overlapping circles of a Ve...
{ "pile_set_name": "PubMed Abstracts" }
Cell-type-specific and projection-specific brain-wide reconstruction of single neurons. We developed a dual-adeno-associated-virus expression system that enables strong and sparse labeling of individual neurons with cell-type and projection specificity. We demonstrated its utility for whole-brain reconstruction of midb...
{ "pile_set_name": "PubMed Abstracts" }
[Cancer of the penis in Cambodia]. The prevalence of penis cancer in Cambodia is comparable with some Far-East and Latino-American countries. Circumcision performed as a religious observance among Jews or undergone as a regular practice among older Moslems children (the Islam Kmers in Cambodia) might provide an indirec...
{ "pile_set_name": "PubMed Abstracts" }
Cattell's Scree Test In Relation To Bartlett's Chi-Square Test And Other Observations On The Number Of Factors Problem. It is demonstrated that Cattell's scree test and Bartlett's chi-square test for the number of factors are both based on the same rationale, so the former reflects statistical (subject sampling) variab...
{ "pile_set_name": "PubMed Abstracts" }
Oriented growth behavior of Ag nanoparticles using SDS as a shape director. We report a chemical approach for synthesizing shape-controlled Ag nanoparticles by using the surfactant SDS as a soft template. The experimental approach includes a two-step reaction: the first step is quickly generating Ag seed clusters by a ...
{ "pile_set_name": "PubMed Abstracts" }
Molecular weights of poly(butyl cyanoacrylate) nanoparticles determined by mass spectrometry and size exclusion chromatography. Matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) and size exclusion chromatography (SEC) were employed to elucidate the chemical composition, mean nu...
{ "pile_set_name": "PubMed Abstracts" }
Integrating phenotypic plasticity within an Ecological Genomics framework: recent insights from the genomics, evolution, ecology, and fitness of plasticity. E.B. Ford's 1964 book Ecological Genetics was a call for biologists to engage in multidisciplinary work in order to elucidate the link between genotype, phenotype,...
{ "pile_set_name": "PubMed Abstracts" }
Interactions of alpha-helices with lipid bilayers: a review of simulation studies. Membrane proteins, of which the majority seem to contain one or more alpha-helix, constitute approx. 30% of most genomes. A complete understanding of the nature of helix/bilayer interactions is necessary for an understanding of the struc...
{ "pile_set_name": "PubMed Abstracts" }
Noncomplement fixing, IgG4 autoantibodies predominate in patients with anti-epiligrin cicatricial pemphigoid. This study characterized the specific reactivity, IgG subclass, and complement fixing ability of anti-laminin-5 IgG from 12 patients with anti-epiligrin cicatricial pemphigoid. Circulating IgG from all patients...
{ "pile_set_name": "PubMed Abstracts" }
Relevance and usability of a computerized patient simulator for continuous medical education of isolated care professionals in sub-saharan Africa. to explore the relevance and usability of using a computerized patient simulator as a tool for continuous medical education and decision support for health professionals in ...
{ "pile_set_name": "PubMed Abstracts" }
The general hospitals' role in the care of the seriously disabled mentally ill. Acute-care general hospitals play an important role in the care of the seriously disabled mentally ill (SDMI), especially in the State of Hawaii. Currently there are 4 private hospitals on the island of Oahu that have acute psychiatric ward...
{ "pile_set_name": "PubMed Abstracts" }
SH479, a Betulinic Acid Derivative, Ameliorates Experimental Autoimmune Encephalomyelitis by Regulating the T Helper 17/Regulatory T Cell Balance. CD4+ T helper cells, especially T helper 17 (TH17) cells, combined with immune regulatory network dysfunction, play key roles in autoimmune diseases including multiple scler...
{ "pile_set_name": "PubMed Abstracts" }
Nuclear trafficking during plant innate immunity. Land plants possess innate immune systems that can control resistance against pathogen infection. Conceptually, there are two branches of the plant innate immune system. One branch recognizes conserved features of microbial pathogens, while a second branch specifically ...
{ "pile_set_name": "PubMed Abstracts" }
Detection of Blastomyces dermatitidis antigen in patients with newly diagnosed blastomycosis. Blastomycosis is a serious and potentially fatal infection, and diagnosis can be difficult at times. We evaluated the diagnostic utility of a commercially available assay for detection of Blastomyces dermatitidis antigen, rece...
{ "pile_set_name": "PubMed Abstracts" }
Physicians' attitudes towards patients' rights legislation. Patients' rights laws, bills and charters aim at delineating the patient-physician relationship in regard to consent to medical treatment, confidentiality and related issues. The need to shape such an intimate relationship by way of legislation seems anomalous...
{ "pile_set_name": "PubMed Abstracts" }
Cost of Immediate Surgery Versus Non-operative Treatment for Trigger Finger in Diabetic Patients. As health care costs continue to rise, providers must increasingly identify and implement cost-effective practice measures without sacrificing quality of care. Corticosteroid injections are an established treatment for tri...
{ "pile_set_name": "PubMed Abstracts" }
Dehydration and clearing of whole mouse brains and dissected hippocampi for ultramicroscopy. This protocol describes the preparation of whole mouse brains and dissected hippocampi for ultramicroscopy (UM), a powerful imaging technique that achieves precise and accurate three-dimensional (3D) reconstructions of intact m...
{ "pile_set_name": "PubMed Abstracts" }
Multilocular cystic renal cell carcinoma is a subtype of clear cell renal cell carcinoma. Multilocular cystic renal cell carcinoma is an uncommon low grade renal cell carcinoma with unique morphologic features. Its cytogenetic characteristics have not been fully investigated. Its relationship to typical clear cell rena...
{ "pile_set_name": "PubMed Abstracts" }
Two new species of Ergasilus Nordmann, 1832 (Copepoda: Ergasilidae) and a redescription of Ergasilus salmini Thatcher & Brazil-Sato, 2008 from Salminus brasiliensis Cuvier and S. franciscanus Lima & Britsky (Teleostei: Characidae) in Brazil. Three species of Ergasilus Nordmann, 1832 are reported from the gills of Salmi...
{ "pile_set_name": "PubMed Abstracts" }
Lipodystrophy: a case report of partial lipodystrophy of the face. Lipodystrophy is a disorder of the subcutaneous adipose tissue. It can occur in two forms--partial and total. Gorlin and Goldman (1970) suggested that facial lipodystrophy can only occur bilaterally, and should it occur unilaterally, then it is hemifaci...
{ "pile_set_name": "PubMed Abstracts" }
Coupling of multiple opioid receptors to GTPase following selective receptor alkylation in brain membranes. Opioid agonists of the mu, kappa and delta types stimulated low-Km guanosine triphosphatase (GTPase) in membranes, from the brain of the rat by up to 34%, with potencies the rank order of which corresponded to th...
{ "pile_set_name": "PubMed Abstracts" }
Cardiovascular calcification in nondialyzed patients with chronic kidney disease. Chronic kidney disease (CKD) has become a major health-care problem of global proportions. Progression to end-stage renal disease (ESRD), the need for renal replacement therapy, and the high annual death rate of dialysis patients are the ...
{ "pile_set_name": "PubMed Abstracts" }
Effect of ultraviolet (UV) A, UVB or ionizing radiation on the cell cycle of human melanoma cells. One important component of the cellular response to irradiation is the activation of cell cycle checkpoints. It is known that both ultraviolet (UV) radiation and ionizing radiation (IR) can activate checkpoints at transit...
{ "pile_set_name": "PubMed Abstracts" }
Nature of M-Ga bonds in dihalogallyl complexes (η5-C5H5)(Me3P)2M(GaX2) (M = Fe, Ru, Os) and (η5-C5H5)(OC)2Fe(GaX2) (X = Cl, Br, I): a DFT study. Density functional theory (DFT) calculations have been performed on the terminal dihalogallyl complexes of iron, ruthenium, and osmium (η(5)-C(5)H(5))(Me(3)P)(2)M(GaX(2)) (M =...
{ "pile_set_name": "PubMed Abstracts" }
Clinical effects of buprenorphine on open field behaviour and gait symmetry in healthy and lame weaned piglets. Lameness in pigs decreases animal welfare and economic profit for the farmer. An important reason for impaired welfare in lame animals is pain due to lameness. No direct measurement of pain is possible in ani...
{ "pile_set_name": "PubMed Abstracts" }
Clinical research in family medicine: quantity and quality of published articles. Publication of clinical research in peer-reviewed journals is an important measure of scholarly productivity. This study determined the quantity and quality of original clinical research published by family physicians. We surveyed clinica...
{ "pile_set_name": "PubMed Abstracts" }
Percutaneous transluminal angioplasty of a large septal artery. A severely stenotic, large-caliber, first septal artery was successfully dilated in a patient with refractory angina and nonsurgical, multivessel coronary artery disease. The success of this dilatation was related to favorable coronary anatomy and to the a...
{ "pile_set_name": "PubMed Abstracts" }
Ultrastructural characteristics and lysozyme content in hypergranular and variant type of acute promyelocytic leukaemia. We investigated the electronmicroscopic (EM) features and cellular lysozyme (LZ) content in 16 cases of acute promyelocytic leukaemia (APL): 11 cases of the hypergranular form (M3) and five cases of ...
{ "pile_set_name": "PubMed Abstracts" }
Fantastic beasts and how to find them-Molecular identification of the mitochondrial ATP-sensitive potassium channel. Despite reported sightings over many years, certain mitochondrial-specific channels have proven to be elusive beasts, evading molecular identification. However, combining modern genetics with a wave of t...
{ "pile_set_name": "PubMed Abstracts" }
Climatic change and its ecological implications at a subantarctic island. Marion Island (47°S, 38°E) has one of the most oceanic climates on earth, with consistently low air temperatures, high precipitation, constantly high humidity, and low incident radiation. Since 1968 mean surface air temperature has increased sign...
{ "pile_set_name": "PubMed Abstracts" }
A fatal case of transfusion-transmitted babesiosis in the State of Delaware. Most cases of human babesiosis in North America are caused by Babesia microti, which is endemic in the northeastern and upper midwestern United States. Although the disease is usually transmitted by a tick bite, there has been an increase in t...
{ "pile_set_name": "PubMed Abstracts" }
Eosinophil cationic protein as a serological marker of disease activity in childhood bronchial asthma. To study the value of eosinophil cationic protein (ECP) as a serological marker of disease activity in childhood bronchial asthma, ECP levels were measured in 20 healthy control children and 25 asthmatic children, dur...
{ "pile_set_name": "PubMed Abstracts" }
MR imaging and MR spectroscopy in prostate cancer management. Currently, endorectal coil MR imaging has the ability to improve accuracy in staging of localized prostate cancer. The addition of MR spectroscopic imaging has further improved the sensitivity of MR imaging for intraprostatic tumor localization. Additional r...
{ "pile_set_name": "PubMed Abstracts" }
A Nanobionic Light-Emitting Plant. The engineering of living plants for visible light emission and sustainable illumination is compelling because plants possess independent energy generation and storage mechanisms and autonomous self-repair. Herein, we demonstrate a plant nanobionic approach that enables exceptional lu...
{ "pile_set_name": "PubMed Abstracts" }
Safety of retigabine in adults with partial-onset seizures after long-term exposure: focus on unexpected ophthalmological and dermatological events. Retigabine is an antiepileptic drug developed for the adjunctive treatment of adults with epilepsy and partial-onset seizures (POS). Following its approval in 2011, report...
{ "pile_set_name": "PubMed Abstracts" }
Effects of oral zinc supplementation on serum leptin levels in Ache males of eastern Paraguay. Significant population variation has been demonstrated in serum leptin levels, independent of adiposity. Included within these populations, Ache males have significantly lower leptin levels compared to American subjects with ...
{ "pile_set_name": "PubMed Abstracts" }
Brain cytokine synthesis induced by an intraparenchymal injection of LPS is reduced in MCP-1-deficient mice prior to leucocyte recruitment. We have previously shown that ischaemic lesions are smaller in monocyte chemoattractant protein-1-deficient (MCP-1(-/-)) mice than in wild-type (wt) controls. In addition to its ro...
{ "pile_set_name": "PubMed Abstracts" }
The role of IFN in the development of NAFLD and NASH. Non-alcoholic fatty liver disease (NAFLD) and its progressive inflammatory form non-alcoholic steatohepatitis (NASH) are major health challenges due to a significant increase in their incidence and prevalence. While NAFLD is largely benign, the chronic liver inflamm...
{ "pile_set_name": "PubMed Abstracts" }
Clinical comparison of monophasic oral contraceptive preparations of gestodene/ethinyl estradiol and desogestrel/ethinyl estradiol. Latin American Oral Contraceptive Study Group. The efficacy, cycle control, subjective complaints, and safety of monophasic preparations of the oral contraceptives containing gestodene 75 ...
{ "pile_set_name": "PubMed Abstracts" }
Crystal Structure of Cleaved Serp-1, a Myxomavirus-Derived Immune Modulating Serpin: Structural Design of Serpin Reactive Center Loop Peptides with Improved Therapeutic Function. The Myxomavirus-derived protein Serp-1 has potent anti-inflammatory activity in models of vasculitis, lupus, viral sepsis, and transplant. Se...
{ "pile_set_name": "PubMed Abstracts" }
Study on the kinetics of keto-enol tautomerism of p-hydroxyphenylpyruvic acid using capillary electrophoresis. The kinetics of keto-enol tautomerism of p-hydroxyphenylpyruvic acid (pHPP) as a model of alpha-carbonyl compounds in aqueous solution at room temperature (25 degrees C) was first investigated by capillary ele...
{ "pile_set_name": "PubMed Abstracts" }
Assessment of hemodynamic disturbances in aphasic patients by transcranial Doppler ultrasonography. The author presents a study of Doppler cerebrovascular ultrasonography carried out in 38 aphasie patients (forms ranging from transient speech disturbances to severe, persistent disturbances of motor, sensory or mixed ap...
{ "pile_set_name": "PubMed Abstracts" }
Development and full validation of a liquid chromatography-tandem mass spectrometry method for determination of carbinoxamine in beagle plasma and its application to a pharmacokinetic study. Carbinoxamine maleate is an antihistamine drug with mild sedation effects, which is used to treat seasonal and perennial allergic...
{ "pile_set_name": "PubMed Abstracts" }
Planar Procrustes analysis of tooth shape. Accurate quantification of variation in tooth shape is important in studies of dental development, which typically have involved measuring distances between subjectively identified landmarks, key points of correspondence on teeth. An established statistical framework now exist...
{ "pile_set_name": "PubMed Abstracts" }
Ranitidine vs metoclopramide in the medical treatment of reflux esophagitis. 45 patients with symptomatic reflux esophagitis were randomly treated with either Ranitidine (150 mg b.i.d.) or Metoclopramide (10 mg t.i.d.) for six weeks. The severity of dyspeptic symptoms and the grade of endoscopic and histological esopha...
{ "pile_set_name": "PubMed Abstracts" }
Part III. Molecular changes induced by high nitric oxide adaptation in human breast cancer cell line BT-20 (BT-20-HNO): a switch from aerobic to anaerobic metabolism. Nutrient deprivation and reactive oxygen species (ROS) play an important role in breast cancer mitochondrial adaptation. Adaptations to these conditions ...
{ "pile_set_name": "PubMed Abstracts" }
Directing visual attention with spatially informative and spatially noninformative tactile cues. We investigated the tactile cuing of visual spatial attention using spatially-informative (75% valid) and spatially-noninformative (25% valid) tactile cues. The participants performed a visual change detection task followin...
{ "pile_set_name": "PubMed Abstracts" }
Tips for succeeding at Internet courses. Ready to go to "cyberschool"? Here's practical advice on making it work for you.
{ "pile_set_name": "PubMed Abstracts" }
Adult exposure to diethylstilbestrol induces spermatogenic cell apoptosis in vivo through increased oxidative stress in male hamster. Effects of diethylstilbestrol (DES), an endocrine disrupting chemical, on abnormal spermatogenesis were studied in adult hamster using daily subcutaneous injection of 0.01, 0.1 and 1.0mg...
{ "pile_set_name": "PubMed Abstracts" }
Pseudo-pseudohypoparathyroidism, empty sella syndrome, and hypopituitarism in a young woman. The confluence of pseudo-pseudohypoparathyroidism, empty sella syndrome, and pituitary insufficiency is reported for the first time. The patient, an 18-year-old woman, was evaluated because of primary amenorrhea. Possible relat...
{ "pile_set_name": "PubMed Abstracts" }
Biocompatibility and biomechanical characteristics of loofah based scaffolds combined with hydroxyapatite, cellulose, poly-l-lactic acid with chondrocyte-like cells. The current study reports the biocompatibility and biomechanical characteristics of loofah-based scaffolds combined with hydroxyapatite (HA), cellulose, p...
{ "pile_set_name": "PubMed Abstracts" }
Muscle strength in knee varus and valgus. The purpose of this study was to investigate the lower-limb muscle strength in knee varus-valgus and its dependence on knee varus-valgus position. The hypothesis was that humans could differentially contract the medial and lateral muscles crossing the knee and generate signific...
{ "pile_set_name": "PubMed Abstracts" }
Production of dairy goat embryos, by nuclear transfer, transgenic for human acid beta-glucosidase. Expression of recombinant human lysosomal acid beta-glucosidase (hGCase) by a transgenic animal bioreactor, using somatic cell nuclear transfer (SCNT), would decrease the cost of producing this product. The objective was ...
{ "pile_set_name": "PubMed Abstracts" }
Enterotoxin gene profile of methicillin-resistant Staphylococcus pseudintermedius isolates from dogs, humans and the environment. This study aimed to detect and identify staphylococcal enterotoxin (SE) genes in methicillin-resistant Staphylococcus pseudintermedius (MRSP) strains from different sources, and to investiga...
{ "pile_set_name": "PubMed Abstracts" }
Rearrangement of beta-amino alcohols via aziridiniums: a review. This tutorial review focuses on the rearrangement of beta-amino alcohols via aziridinium intermediates. It covers the literature from 1947 to January 2009 (55 references). The rearrangement of beta-amino alcohols can be performed by activation of the hydr...
{ "pile_set_name": "PubMed Abstracts" }
The effect of vigorous exercise during pregnancy on birth-weight. The aim of this study was to assess the effect on birth-weight of continuing a programme of vigorous exercise into late pregnancy. 'Potential exercisers' were women who had been doing vigorous exercise prior to pregnancy and intended to continue exercisi...
{ "pile_set_name": "PubMed Abstracts" }
Differential accumulation of silymarin induced by exposure of Silybum marianum L. callus cultures to several spectres of monochromatic lights. Silybum marianum L. (Milk thistle) is one of the most extensively studied medicinal herbs with well-known hepatoprotective activity. Light is considered as a key abiotic elicito...
{ "pile_set_name": "PubMed Abstracts" }
A clinico-pathological study of canine Cushing's disease caused by a pituitary carcinoma. Knowledge of clinico-pathological correlations in canine Cushing's disease is rather poor. Therefore we describe, clinically and pathologically, a case of pituitary tumour-dependent Cushing's disease in an 8-year old female cocker...
{ "pile_set_name": "PubMed Abstracts" }
Clinical experience using intrathecal (IT) bupivacaine infusion in three patients with complex regional pain syndrome type I (CRPS-I). To date, there is no reliable method for treating the severe pain and for modifying the natural evolution of CRPS-I. Therefore, we explored the effect of long-term IT bupivacaine infusi...
{ "pile_set_name": "PubMed Abstracts" }
Cerebral oxidative metabolism failure in traumatic brain injury: "Brain shock". Shock is a systemic form of acute circulatory failure leading to cellular dysoxia and death. Such a state of aerobic metabolism failure also underlies neuronal cell death in severe traumatic brain injury. It is becoming increasingly recogni...
{ "pile_set_name": "PubMed Abstracts" }
A systematic methodology to extend the applicability of a bioconversion model for the simulation of various co-digestion scenarios. Detailed simulation of anaerobic digestion (AD) requires complex mathematical models and the optimization of numerous model parameters. By performing a systematic methodology and identifyi...
{ "pile_set_name": "PubMed Abstracts" }
Narrow band imaging is a new technique in visualization of recurrent respiratory papillomatosis. Recurrent respiratory papillomatosis (RRP) is a rare, benign, wart-like disease for which no curative treatment exists. The goal of treatment is total surgical removal of the epithelial lesions to keep the airway open and t...
{ "pile_set_name": "PubMed Abstracts" }
[5 years of experience in the treatment of parkinsonism with L-dopa and its combination with Ro4-4602]. Eighty-one Parkinsonic patients were treated with L-dopa alone and/or combined with Ro4-4602, during 27 to 60 months. The results are reported. 7.2% of the patients, who are still being treated, showed good, very goo...
{ "pile_set_name": "PubMed Abstracts" }
Modeling ebola virus disease transmissions with reservoir in a complex virus life ecology. We propose a new deterministic mathematical model for the transmission dynamics of Ebola Virus Disease (EVD) in a complex Ebola virus life ecology. Our model captures as much as possible the features and patterns of the disease e...
{ "pile_set_name": "PubMed Abstracts" }
Bond strength of fiber posts after the application of erbium:yttrium-aluminum-garnet laser treatment and gaseous ozone to the root canal. The aim of the present study was to investigate the effects of antibacterial agents (erbium:yttrium-aluminum-garnet [Er:YAG] laser or gaseous ozone) intended to disinfect root canals...
{ "pile_set_name": "PubMed Abstracts" }
Shear adhesion strength of thermoplastic gecko-inspired synthetic adhesive exceeds material limits. Natural gecko array wearless dynamic friction has recently been reported for 30,000 cycles on a smooth substrate. Following these findings, stiff polymer gecko-inspired synthetic adhesives have been proposed for high-cyc...
{ "pile_set_name": "PubMed Abstracts" }
Magnetic resonance techniques in musculoskeletal diseases. Magnetic resonance imaging provides a sensitive technique for detection of musculoskeletal pathology. In order to optimize this information and properly characterize lesions, it is important to select carefully image parameters. Patient selection criteria are a...
{ "pile_set_name": "PubMed Abstracts" }
Cardiopulmonary limitations to exercise in restrictive lung disease. Cardiopulmonary limitations to exercise in restrictive lung disease. Med. Sci. Sports Exerc., Vol. 31, No. 1 (Suppl.), pp. S28-S32, 1999. Restrictive lung disease encompasses a large and diverse group of disorders characterized by a diminished lung vo...
{ "pile_set_name": "PubMed Abstracts" }
Skull Base Chondrosarcoma Caused by Ollier Disease: A Case Report and Literature Review. Ollier disease (OD) is a rare, nonhereditary bone disease that is characterized by the presence of multiple enchondromatosis (3 or more) with a typical asymmetric distribution which is mainly confined to the appendicular skeleton. ...
{ "pile_set_name": "PubMed Abstracts" }
Calf muscle work and segment energy changes in human treadmill walking. The relation between changes in potential and kinetic energy in a seven-segment model of the human body and the work of m. triceps surae was investigated in four subjects walking on a treadmill at speeds between 0.5 and 2.0 m/s. Segment energy leve...
{ "pile_set_name": "PubMed Abstracts" }
Twenty-year outcome of cutaneous vesicostomy. Forty cutaneous vesicostomy urinary diversions were done at our hospital from 1958 to 1961. Of these cases 30 patients have been followed every 6 months or until death. The vesicostomy-related failure rate was 8.6 per cent, with new stones forming in 3 additional kidneys. C...
{ "pile_set_name": "PubMed Abstracts" }
Enhanced expression of potassium-chloride cotransporter KCC2 in human temporal lobe epilepsy. Synaptic reorganization in the epileptic hippocampus involves altered excitatory and inhibitory transmission besides the rearrangement of dendritic spines, resulting in altered excitability, ion homeostasis, and cell swelling....
{ "pile_set_name": "PubMed Abstracts" }
Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway. STAT proteins (signal transducers and activators of transcription) are latent cytoplasmic transcription factors that are phosphorylated by Janus kinases in response to cytokines. Phosphorylated STAT proteins translocate to the nucleus, ...
{ "pile_set_name": "PubMed Abstracts" }
Development of a Tumor-Responsive Nanopolyplex Targeting Pancreatic Cancer Cells and Stroma. Desmoplasia plays a pivotal role in promoting pancreatic cancer progression and is associated with poor clinical outcome. Targeting the desmoplastic tumor microenvironment in combination with chemotherapy is therefore a promisi...
{ "pile_set_name": "PubMed Abstracts" }
Stress in dentistry. Dentists believe their profession is stressful. Research has indicated this belief is generally based upon patient behaviors and economic pressures. A discussion of stress and adaptation is presented. Since stress can lead to both physical and emotional problems, recognition of stress by the practi...
{ "pile_set_name": "PubMed Abstracts" }
Current scenario and future strategies to fight artemisinin resistance. Despite several setbacks in the fight against malaria such as insecticide and drug resistance as well as low efficacy of available vaccines, considerable success in reducing malaria burden has been achieved in the past decade. Artemisinins (ARTs an...
{ "pile_set_name": "PubMed Abstracts" }
Loss of natural dentition: multi-level effects among a geriatric population. To quantify the impact of edentulousness on residual ridge volume, denture stomatitis (DS), as well as oral health behaviours among geriatric denture-wearers. Residual ridge resorption (RRR) is the primary intraoral complication of complete ed...
{ "pile_set_name": "PubMed Abstracts" }
Ultraviolet radiation-induced ubiquitination and proteasomal degradation of the large subunit of RNA polymerase II. Implications for transcription-coupled DNA repair. We have shown previously that UV radiation and other DNA-damaging agents induce the ubiquitination of a portion of the RNA polymerase II large subunit (P...
{ "pile_set_name": "PubMed Abstracts" }
[The phenotypic heterogeneity of meningococcal strains by their serogroup trait]. It is shown that heterogeneity of meningococci of the outlined serogroups is formed due to appearance of nonagglutinable individuals in subpopulations but heterogeneity of polyagglutinable strains is characterized by incorporation not onl...
{ "pile_set_name": "PubMed Abstracts" }
Adenocarcinoma of the head of the pancreas: determination of surgical unresectability with thin-section pancreatic-phase helical CT. This study was conducted to evaluate newly introduced criteria for unresectability of pancreatic cancer with thin-section pancreatic-phase helical CT. Twenty-five patients with adenocarci...
{ "pile_set_name": "PubMed Abstracts" }