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135
c97feee4-ffba-49fc-902a-de58c92daae2
Bence jones proteins are associated with
Hodgkin's lymphoma
Multiple myeloma
Burkitt's Lymphoma
Infectious mononucleosis
1b
single
null
Pathology
null
1f1221f7-7b31-4d65-a8a6-8ab04e99c87a
Hyperprolactinoma causes
Inter menstrual bleeding
Prolonged menstruation
Oligomenorrhea
Polymenorrhea
2c
single
(Oligomenorhea): (2287-88- H18th edition; 788-Davidson 21st)HYPER PROLACTINEMIA* Hyper prolactinemia is the most common pituitary hormone hyper secretion syndrome in both men and women* PRL- secreting pituitary adenoma (Prolactinomas) are the most common cause of PRL levels > 200 mg/L* Pregnancy and lactation are the i...
Medicine
Endocrinology
5ead0e2c-a7ff-489b-ab95-7ec147c4f0f9
Which of the following statement about Bradykinin is true:
Causes pain
Causes bronchodilation
Causes vasoconstriction
Decreases vascular permeability
0a
multi
A i.e. Causes PainBradykinin increases vascular permeability, and causes contraction of smooth muscle (utrine, intestine, bronchoconstriction), dilation of blood vessels and painQ when injected into the skin. These effects are similar to those of histamine.
Physiology
null
75f41502-56c7-44bb-8ee2-1b50dc9a9166
Suxamethonium is
Non depolarizing muscle relaxant
Direct acting muscle relaxant
Depolarising muscle relaxant
All of the above
2c
multi
Depolarizing neuromuscular blockers Succinylcholine (SCh., Suxamethonium), Side effects:- Muscle fasciculations and soreness, changes in BP and HR, arrhythmias, histamine release and K+ efflux from muscles causing hyperkalaemia. Uses:- SCh is the most commonly used muscle relaxant for passing tracheal tube. It induces ...
Pharmacology
Anesthesia
a0b7cfe7-12e9-4294-9c7c-5f488311a1c8
Movement across socioeconomic levels is termed as –
Social equality
Social upliftment
Social mobility
Social insurance
2c
single
Social mobility is the degree to which an individual's family or group's social status can change throughout the course of their life through a system of social hierarchy, i.e. Social mobility refers to movement of individuals/ families across different socioeconomic levels. Social Upliftment Social upliftment refer...
Social & Preventive Medicine
null
89f196fa-9d25-48e3-be78-d668f9ab0506
Ascorbic acid is a potent enhancer of iron absorption because it
Enhances the absorption of heme iron
Enhances the activity of heme oxygenase
Is a reducing agent, thereby helping to keep iron in the ferrous state
Decreases the production of ferritin by enterocytes
2c
single
Ascorbic acid enhances iron absorption mostly by its reducing capacity, keeping iron in the ferrous state. Ascorbic acid does not enhance heme iron absorption, nor does it affect heme oxygenase activity or the produc on of ferritin or transferrin.
Anatomy
All India exam
8472b29d-4430-4b8c-a0d1-328b5902914b
Veins communicating the cavernous sinus to pterygoid plexus pass through fossa of :
Scapra
Vesalius
Ovale
Langer
1b
single
B i.e. Vesalius; C i.e. OvaleForamen Vesalius is an inconstant foramen that gives passage to an emissary vein that connects pterygoid venous plexus with cavernous sinus (vein of vesalius)Q. It is also k/a sphenoidal emissary foramen as its seen in the great wing of sphenoid, medial to foramen ovale, opposite the root o...
Anatomy
null
50dba6ee-35b2-44a3-880b-8e1fe35777af
Mucosal candidiasis is caused by
Candida albicans
Candida tropicalis
Candida guilliermondi
Candida krusei
0a
single
(A) Candida albicans # Mucosal Candidiasis> Candidosis describes a group of yeastlike fungal infections involving the skin and mucous membranes.> Infection is caused by Candida species, typically, Candida albicans.> Acute pseudomembranous candidiasis (thrush)> Thrush may be observed in healthy neonates or in persons in...
Medicine
Miscellaneous
24cf9b22-7272-4c64-8adb-9ff3c96a9f79
Clearance -
Refers to the efficacy of elimination of a drug by an organ or whole body
Cannot be greater than blood flow to an organ
Determines the steady of the drug concentration
All the above
3d
multi
Ans. is 'd' i.e., All of the above Clearance of a drug is the theoretical volume of plasma from which the drug is completely removed in unit time.
Pharmacology
null
4994c00f-ab0c-4968-b089-dce435a14635
An absolute contraindication for extraction of teeth is:
Hypertension
Myocardial infarction
Thyrotoxicosis
Central hemangioma
3d
single
null
Surgery
null
2584d677-78f6-4efd-a478-0689d9d46cd9
Who is the chairman of district blindness control society?
District collector
Programme manager
District health officer
District eye surgeon
0a
single
Ans. a. District collector (Ref: Park 23/e p439, 22/e p406; www.nrhmtn.gov.in/dbcs.html)District collector is the chairman of district blindness control society.District Blindness Control Society has been established under the chairmanship of District Collector/Deputy Commissioner. Park 23/e p439District Blindness Cont...
Social & Preventive Medicine
Health Programmes in India
76f701b1-7c4d-4603-ae36-0f3cba641385
An 18 months baby can do?
Hide and seek game
Write alphabet
Say short sentence
Run
0a
single
a. Hide and seek game(Ref: Nelson's 20/e p 65-77, Ghai 8/e p 52-54)Hide and seek game or peek a boo comes at around 10 months age.
Pediatrics
Growth, Development, and Behavior
2e6bf31f-446e-47fa-8b9b-d0aa761178c0
A newborn baby presented with profuse bleeding from the umbilical stump after bih. Rest of the examination and PT, APTT are within normal limits. Most of probable diagnosis is:
Factor X deficiency
Glanzmann thrombasthenia
von-Willebrand disease
Bernard-Soulier disease
0a
single
Ans. a. Factor X deficiency
Pathology
null
0b1721a6-e581-4285-b439-8837740d3048
A 37-year-old man develops pulmonary hemorrhage and glomerulonephritis. Lung biopsy with immunofluorescence demonstrates IgG deposition along the basement membrane. These antibodies are most likely directed against which of the following types of collagen?
Type I
Type II
Type III
Type IV
3d
single
Goodpasture syndrome Autoimmune disease Ceain domains of type IV collagen are intrinsic to the basement membranes of renal glomeruli and pulmonary alveoli. Resulting in necrotizing hemorrhagic interstitial pneumonitis and rapidly progressive glomerulonephritis. The characteristic linear pattern of immunoglobulin deposi...
Pathology
Glomerulonephritis
3722513b-7fb7-434e-ac84-8f1a9520fdeb
Most common cause of Cheyne-Stokes breathing is?
Diabetic ketoacidosis
CHF
Bulbar polio
Pontine hemorrhage
1b
single
Ans. is'b'i.e., CHF(Ref Clinicalmedicine p. 713)Cause of Cheyne-Stokes respiration,Normally occurs during sleep at high altitudeCongestive cardiac failureDamage to respiratory centers
Physiology
null
9d5a4ee9-ee8c-4652-aab1-c8b1cea5ef5b
Most stable in closed reduction is
Screws
Arch bar
Direct wiring
None of the above
1b
multi
null
Surgery
null
1ead7ac8-b29e-4036-b3eb-afa380b27f6b
The drug of choice for mushroom poisoning is which of the following?
Atropine
Carbachol
Adrenaline
Physostigmine
0a
single
Symptoms of mushroom poisoning are due to excess of muscarine. The polypeptides from these mushrooms are inhibitors of cellular protein synthesis and stimulates post ganglionic cholinergic fibres. Atropine sulphate is the preferred drug of choice to counteract the muscarinic effects. Ref: The Essentials of Forensic Med...
Forensic Medicine
null
880bcc07-2a2b-480d-b291-a11dab0beb98
Toxins are implicated as the major pathogenic mechanism in all of the following bacterial diarrhoeas except -
Vibrio cholerae
Shigella sp.
Vibrio parahemolyticus
Staphylococcus aureus
2c
multi
null
Microbiology
null
9afd1e0b-60bb-4cbd-bb54-0827554a64c8
Hepatocellular damage of wilson's resembles ?
Acute hepatitis
Chronic hepatitis
Cholestasis
All
3d
multi
Ans. is 'a' i.e., Acute hepatitis; 'b' i.e., Chronic hepatitis; 'c' i.e., CholestasisWilson diseaseo This autosomal - recessive disorder is marked by the accumulation of toxic levels of copper in many tissues and organs, principally the liver, brain and eye.Clinical features of Wilson's disease?Organs involved Symptoms...
Pathology
null
af4a7d33-6269-48f6-9aac-279415a06ad4
28-year old male while playing was hit on the head by a cricket ball . This hit fractures the orbit and damage the optic canal. Which of the following structures are most likely to be damaged during this hit are -
Optic nerve and ophthalmic aery
Ophthalmic vein and occulomotor aery
Ophthalmic aery and olfactory nerve
Ophthalmic nerve and optic nerve
0a
multi
Floor of Anterior Cranial Fossa is formed by :- 1)Cribriform plate of ethmoid bone 2)Frontal bone 3)Lesser wing of sphenoid Frontal bone and lesser wing of sphenoid contribute in forming roof of orbit Lesser wing of sphenoid contains optic canal for passage of ophthalamic aery and optic nerve (2nd CN) Ophthalmic aery i...
Ophthalmology
Trauma
d08adabd-4cff-4b39-a852-e87801715cdd
Net weight gain in pregnancy is :
11 lb
24 lb
36 lb
42 lb
1b
single
24 lb
Gynaecology & Obstetrics
null
4a350277-afdf-4184-8962-e26e5e35499d
Movements of pronation and supination occurs in all the following upper limb joints, EXCEPT?
Superior radio - ulnar joint
Middle radio - ulnar joint
Inferior radio - ulnar joint
Radio - carpal joint
3d
multi
Supination and pronation movements are not possible in radio-carpal(wrist) joint because the aicular surfaces are ellipsoid shaped. Supination and pronation movements are possible in superior, middle and inferior radio-ulnar joints.
Anatomy
null
b56278be-0654-4b2b-8c7f-f9dc1ab8f045
Oral contraceptive pill containing progesterone which is given in small quantities for 30 days a month is known as :
Micro pill
Sequential pill
Combined pill
None of the aboveq
0a
multi
Micro pill
Gynaecology & Obstetrics
null
79a35afd-ab5f-4e06-9171-05679b2d0a83
A 2 year old boy presented with congested cardiac failure, with right to left shunt. What is the diagnosis?
Dandy Walker malformation
Vein of Gallen malformation
Mega cisterna magna
Crouzon syndrome
1b
multi
(B) Vein of Gallen malformation[?]Communicating Hydrocephalus:There is free flow throughout the ventricular system.Impaired CSF resorption by the arachnoid granulation accounts for majority of casesSAHInfectious meningitisMalignant meningitisGranulomatous meningitis: TB, sarcoidosisAltered venous Dynamics: Vein of Gale...
Pediatrics
C.V.S.
429cffde-57a8-4780-a074-6fef010c09e1
Which cereal is not to be given in celiac sprue
Wheat
Maize
Corn
Rice
1b
single
The precise mechanism of mucosal damage is unclear but immunological responses to gluten play a key role . There is a strong genetic component, with around 10% of first-degree relatives of an index case affected, and there is strong (approximately 75%) concordance in monozygotic twins. There is a strong association wit...
Medicine
G.I.T
8dd199ee-2bf1-40aa-a424-9d079136d019
In staphylococci, plasmids encoding beta lactamase are transmitted by
Conjugation
Transduction
Transposon
Transformation
1b
single
Ref Goodman Gilman 11/e p 1133 Beta lactamase are encoded by plasmids that can be transferred with the help of bacteriophage in staphylococci and by transformation in pneumococci
Pharmacology
Chemotherapy
bf1bfde4-bad0-40f6-9ecf-b7b65aa974ab
Gottron's papules are seen in -
Dermatomyositis
Sarcoidosis
Scleroderma
Fungal infection
0a
single
Ans. is 'a' i.e., Dermatomyositis Cutaneous signs of dermatomyosits1. Gottron's papules lilac or violaceous papules on knuckle, dorsa of hands.2. Gottron's sign Violaceous erythema with edema over shoulder, arms, forearms.3. Heliotrope sign Violaceous erythema with edema over eyelids, periorbital region.4. Poikiloderma...
Skin
Autoimmune Skin Disorders
531b4a7c-b703-4a39-b0eb-ba08701c68d1
The best method of teaching an urban slum about ORS is –
Lecture
Role play
Demonstration
Flash cards
2c
single
Demonstration A demonstration is a carefully prepared presentation to show how to perform a skill or procedure. Demonstration as a means of communication has been found to have a high educational value in programmes like- Environmental sanitation → installation of a hand pump, construction of a sanitary latrine. Mo...
Social & Preventive Medicine
null
b05cd128-8c35-488b-aed3-18157fe6349c
45-year-old policeman comes from duty with complain of pain in right leg. On examination, pulse in right popliteal fossa was absent and pain in right buttock, where as in left side it was normal. The block is at which level?
Femoral
Iliac
Aooiliac
Popliteal
1b
single
As the pulse is absent in right popliteal fossa and also there is impaired blood supply in right buttock and left side is normal, the block lies in the right sided iliac vessel. Image showing blood supply of pelvis and lower limb. If block is in femoral or popliteal vessels, there will be no pain in buttocks. If aooili...
Anatomy
FMGE 2019
8ad6f05f-dbe0-4e5f-a78b-e93cd27ddc59
A first-grade teacher is concerned about a 6- year old girl in her class who has not spoken a single word since school staed. The little girl paicipate appropriately in the class activities and uses gestures and drawings and nods and shakes her head to communicate. The parents repo that the little girl talks only in th...
Autism
Expressive language disorder
School phobia
Selective mutism
3d
single
In selective mutism, a child voluntarily abstains from talking in paicular situations (usually at school) while remaining appropriately verbal at home. Some children only speak with their parents and siblings and are mute with relatives and friends. Children with selective mutism do not have a language impediment, nor ...
Surgery
null
9ea6f002-2ebc-41ce-8465-804bbf62a9dd
The major contribution of amniotic fluid after 20 weeks of gestation :
Ultrafiltrate and maternal plasma
Fetal urine
Fetal lung fluid
Fetal skin
1b
single
Origin of amniotic fluid : Early week -Maternal plasma 2 nd trimester - Fetal skin Beyond 20 weeks -Fetal urine Ref: Datta Obs 9e pg 34.
Anatomy
General obstetrics
c14b4ee8-7005-41e5-8423-503d6d34d229
Complication of massive blood transfusion?
Hypercalcemia
Hypermagnesemia
Hyperkalemia
Hyperthermia
2c
single
Ans is 'c' i.e. Hyperkalemia * The potassium concentration of blood increases during storage & massive transfusion of units containing increased potassium may lead to hyperkalemia - adding to elevated potassium levels caused by severe shock, renal dysfunction and muscle necrosis.Massive blood transfusion* A massive blo...
Anaesthesia
Complications Of Anaesthesia
36e185f4-d9b3-4fc1-8569-5fd949022261
Uterus and cervix develop from
Mullerian duct
Wolffian duct
Mesonephirc duct
None
0a
multi
Two embryonic structures that play an impoant role in the development of the urogenital system are the intermediate mesoderm and the cloaca. Intermediate Mesoderm is subdivided into three pas: 1. Paraxial mesoderm which becomes segmented to form the somites. 2. Lateral plate mesoderm in which the intraembryonic coelom ...
Anatomy
General anatomy
41eb29fe-1b14-4b8f-9fe3-1dd97e201068
Red cell Protoporphyrin levels more than 100 microgram/ dL is suggestive of which of the following?
Iron deficiency anemia
Lead poisoning
Myelodysplasia
All
0a
multi
Ans. a (Iron deficiency anemia) (Ref. Harrison 18th/ ch. 103)RED CELL PROTOPORPHYRIN LEVELS# Protoporphyrin is an intermediate in the pathway to heme synthesis.# Under conditions in which heme synthesis is impaired, protoporphyrin accumulates within the red cell.# This can reflect an inadequate iron supply to erythroid...
Pediatrics
Blood
7a192af7-3cae-48cd-8cb7-dd37ef71a3b0
All of them are true about retinoblastoma except
Rb1 gene is located on 11q14
The commonest cause of intraocular calcification
Trilateral retinoblastoma is a combination of bilateral retinoblastoma with pinealoblastoma
The commonest tumour of the eye in children
0a
multi
Retinoblastoma (RB) gene has been identified as 14 band on the long-arm of chromosome 13 (13q 14) and is a 'cancer suppressor' or 'antioncogenic' gene. Deletion or inactivation of this protective gene by two mutations (Knudson's two hit hypothesis) results in occurrence of retinoblastoma. Retinoblastoma is commonest tu...
Ophthalmology
Retina
90396d2b-c4e8-4b35-ad76-0c29fe86aee6
Which nerve is involved in this presentation?
Long thoracic Nerve
Musculocutaneous nerve
Lateral anterior thoracic nerve
Thoracodorsal nerve
0a
single
Ans. A long thoracic nerveNerve involvedMuscleLong thoracic NerveSerratus anteriorMusculocutaneous NerveCoracobrachialis muscleLateral anterior thoracic NervePectoralis major muscleThoracodorsal NerveLatissimus Dorsi
Anatomy
Upper Extremity
3be70e84-87d6-49f7-a3b9-9d4ca00e3c49
Shoest incubation perion in malaria -
P. vivax
P. falciparum
P. malariae
P. ovale
1b
single
Duration of erythrocytic schizogony 48 hrs- vivax Less than or equal to 48 hrs-falciparum 72 hrs -malariae 48 hrs -ovale (refer pgno:58 baveja 3 rd edition)
Microbiology
parasitology
64c013f4-f570-488a-9bf9-724d26969915
other name of othello syndrome is called as
delusion of infedility
delusion of love
delusion of doubles
delusion of persecution
0a
multi
othello syndrome is called as delusion of marital infedility othello syndrome is common in alcoholic males this is is the most repeatedly asked question in entrance examinations the possible mechanism that is told for othello syndrome is that alcohol causes sexual dysfunction in males and thus inturn results in doubtin...
Psychiatry
Schizophrenia and other psychotic disorders
63c482ac-6993-48d1-a9e1-8dd118a2cc72
Clasp arms serves the function of
Stabilization
Reciprocation
Retention
Both 2 and 3
3d
multi
Function and Position of Clasp Assembly Parts
Dental
null
669f60b4-3d3e-41a4-b8a0-ea4000beb805
All of the following drugs are documented to be porphyrinogenic EXCEPT:
Estrogen therapy
Carbamezapine
Phenytoin
Aspirin
3d
multi
Aspirin is not a porphyrinogenic drug. There is a very exhaustive list of drugs given in the table from Harrison; I am giving some impoant drugs! Carbamezapine , chloramphenicol, clindamycin Dihydroergotamine , droperidol Hydralazine Fosphenytoin Indinavir Ketamine, ketoconazole Lidocaine Medroxyprogesterone , mifepris...
Medicine
null
1c8ff099-f148-4aac-ac4a-75a265160555
A patient of Varicose veins came to hospital; intern was on duty. Which test he shall perform to rule out the DVT?
Brodie Trendelenburg test
Pehes test
Thomas test
Ober test
1b
multi
Pehes test is used to differentiate between Varicose veins and Deep vein thrombosis. The limb is elevated and an elastic bandage is applied firmly from the toes to the upper 1/3 of the thigh to obliterate the superficial veins only. With the bandage applied the patient is asked to walk for 5 minutes. If deep system is ...
Surgery
FMGE 2019
7696ede2-c9e8-4456-be34-06db9d59b386
All of the following glands are supplied by the facial nerve, EXCEPT?
Nasal glands
Lacrimal gland
Parotid gland
Submandibular gland
2c
multi
Parotid glandreceives parasympathetic innervations from glossopharyngeal nerve and not facial nerve.
Anatomy
null
33506d0d-cd52-40b8-88f3-e3371cca3ff4
A female neonate is noted at birth to have a gross deformity of her lower back. Examination of the subcutaneous lesion reveals disorganized neural tissue with entrapment of nerve roots. What is the appropriate diagnosis?
Meningocele
Meningomyelocele
Rachischisis
Spina bifida occulta
1b
single
Neural tube defects (dysraphic anomalies) reflect impaired closure of the dorsal aspect of the vertebral column. These abnormalities are classified according the extent of the defect, ranging in severity from spina bifida occulta to meningocele, meningomyelocele, and rachischisis. Spina bifida (choice D) is restricted ...
Pathology
Central Nervous System
106b63a5-3139-4ca8-bb74-12fbce1de52f
Best time for surgery in case of combined unilateral cleft lip and hard palate is
15-18 months
3 - 6 months
6 - 9 months
9- 15 months
0a
single
If cleft is in hard palate surgery is done between 15-18 months.
Surgery
null
7bc92e64-6559-4216-bcce-f97d89db6f8b
Keratin of skin and nail differ because
Vander waal bond
Lipolysis
Disulphide bond
Covalent bond
2c
single
Keratins - Keratins are proteins present in hair, skin and nails, horn, hoof, etc. The fibers present are called alpha keratins and matrix as keratohyalin. They mainly have the alpha helical structure. Each fibril has 3 polypeptide chains and each bundle has about 10-12 fibrils. The keratohyalin matrix has cysteinerich...
Biochemistry
Metabolism of carbohydrate
0b79d349-c087-477e-ba37-de5ababcdcc9
Conventional contraception is: September 2006
OCP
Surgical sterilization
Condoms
IUCD
2c
single
Ans. C: Condoms Barrier methods of contraception involve the use of device that prevents the passage of sperm through canal. Due to many reasons, use of condom is the most popular conventional contraceptive device worldwide. These are cheaper and relatively simple to use, but when used alone, the pregnancy rate is rela...
Gynaecology & Obstetrics
null
47ce02db-2d30-4a03-8967-dbbb9a1c6bcd
Following are true with respect to genus Neisseria Except
Gram negative
Anaerobic
Non-sporulating
Oxidase positive cocci
1b
multi
Neisseria genus is gram-negative cocci, It is oxidase positive, non-sporulating, aerobic and non-motile cocci typically arranged in pairs. Reference: Textbook of Microbiology; Anathanarayan and panicker's; 10th edition; Page no: 230
Microbiology
Bacteriology
49ec42e8-010f-4853-b49a-c44602d166b5
The impression for a diagnostic cast of a partial edentulous mouth should be taken in:
Impression wax
Modelling compound
Hydro-colloid
Hydro cal
2c
single
null
Dental
null
80d3fc65-a63c-4133-ab40-6edc42857b6b
The nerve roots blocked in pudendal nerve block is :
L1,2,3
L2,3
S2,3,4
S4
2c
single
Pudendal nerve arises from S2,3,4 roots Pudendal block will block all the roots. Ref: Datta Obs 9e pg 480.
Anatomy
General obstetrics
32f3ad4d-d2a6-4dda-b6b0-174023d2efdb
Senile ptosis is:
Neurogenic
Myogenic
Aponeurotic
Mechanical
2c
single
Ans/. Aponeurotic
Ophthalmology
null
14e0b9b5-2bd4-46f8-b69a-a393057c8001
Anterior maxillary occlusal projection shows all of the following except:
Anterior maxilla
Teeth from 1st premolar to 1st premolar
Teeth from canine to canine
Anterior floor of the nasal fossa
1b
multi
In anterior maxillary occlusal projection, the central ray is oriented through the tip of nose toward the middle of film with approximately +45 degrees vertical angulation and 0 degrees horizontal angulation. The primary field of this projection includes the anterior maxilla and its dentition, as well as the anterior f...
Radiology
null
b27085d6-bf74-4ea6-9348-5e1132c1972a
A 38-year-old male presented with a suspected diagnosis of suppurate labyrinthitis. A positive Rinne's test and positive fistula test was recorded on initial examination. The patient refused treatment, and returned to the emergency depament after 2 weeks complaining of deafness in the affected ear. On examination, fist...
True positive Rinne's test
False positive Rinne's test
True negative Rinne's test
False negative Rinne's test
3d
multi
In severe SNHL: Rinne's test is false negative and because labyrinth is dead. Fistula test is negative.False negative Rinne test occurs in case of severe SNHL because patient does not perceive any sound of tuning fork by air conduction but responds to bone conduction due to intracranial transmission of sound from oppos...
ENT
null
4aa92dbb-e603-47f9-956c-445b77fed1d4
Which of the following is an increased risk of breast cancer?
Sclerosing adenosis
Atypical hyperplasia
Fibroadenoma
Florid hyperplasia
1b
single
Ans is b i.e. Atypical hyperplasia A history of breast biopsy for benign breast disease have an increased risk of breast cancer. The degree of increase in risk depends on the specific epithelial abnormality. The table below shows the relative associated risks for patients with benign histologic findings. American Board...
Surgery
null
c8e729ed-d3fb-4dce-8db9-f58bda30ba41
Most specific antiemetic for chemotherapy induced vomiting is:
Granisetron
Tegaserod
Domperidone
Doxylamine
0a
single
Ans. (A) Granisetron(Ref: Harrison 20th/e p501)Drugs for chemotherapy induced vomiting5 HT3 blockers like ondansetron, granisetron, dolasetron, palonosetron and ramosetron are DOC for this condition.Palonosetron is most potent 5 HT3 blocker. Dolasetron may prolong QT interval.Palonosetron has longest t1/2 whereas ondan...
Pharmacology
G.I.T
2ab5999f-e897-4b04-af86-be7183f3eeb5
Maple syrup urine disease is characterised by all except -
Hypotonia
Hypertonia
Pancreatitis
Hypopigmentation
3d
multi
Ans. is 'd' i.e., Hypopigmentation* Maple syrup urine disease is caused by a defect of branched chain keto acid dehydrogenase (BCKADH), the enzyme which is involved in the catabolism of branched chain amino acids - valine, leucine and isoleucine* The disorder is so called because of the classic sweet odour observed in ...
Biochemistry
Proteins and Amino Acids
36cdda96-0d7c-482c-b0c8-c6aba464c62c
The typical appearance of 'Granulation tissue' is due to
Thrombosed capillaries
Budding ends of capillaries
Densely packed collagen
Chronic inflammatory cells
1b
single
The term granulation tissue derives from its pink, so, granular appearance on the surface of wounds, and the characteristic histological features include the formation of the new vessels (angiogenesis) with budding ends of capillaries and proliferation of fibroblast.
Pathology
All India exam
5b4d7649-a542-4762-b5b7-3a6a79ae5492
Which of the following drugs should be sold only on prescription of a registered medical practitioner?
Schedule H drugs
Schedule X drugs
Schedule J drugs
Schedule Y drugs
0a
single
(a) Schedule H drugsRef: Sharma & Sharma's Principles of Pharmacology, 3rd edpg. 6 and style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">.in/newsite/PrintRelease.aspx?re/id=101251* According to the drugs and cosmetic act, 1940 (rules 1945), schedule H deals with the drugs which must be s...
Pharmacology
General Pharmacology
45e20714-ddfc-444d-bd73-7a212bf1d315
Blau syndrome is associated with mutation of:
NOD2/CARD 15 gene
NOD 1/CARD 1 gene
NOD2/CARD 10 gene
NOD3/CARD 12 gene
0a
single
Ans: (a) NOD2/CARD 15 geneRef: Harrison, 19th edition, Page 2215 and Genetic Home ReferenceBlau's syndromeCaused by mutations in CARD15 (also known as NOD2), which regulates nuclear factor-xB activation.The protein produced from this gene helps defend the body from foreign invaders, such as viruses and bacteria, by pla...
Pathology
Genetics
bf916622-79ca-4c94-885d-6e73669171be
Which cooking oil bast most PUFA?
Safflower oil
Coconut oil
Butter
Vanaspati
0a
single
Ans. is 'a' i.e., Safflower oil
Social & Preventive Medicine
null
8dcbd9d1-33ab-4e5c-9167-be70a888255c
Supranuclear lesion of facial nerve affects
Lower pa of face
Upper pa of face
Face
Spares Face
0a
single
It is caused by cerebrovascular accidents (haemorrhage, thrombosis or embolism), tumour or an abscess. It causes paralysis of only the lower half of face on the contralateral side. Forehead movements are retained due to bilateral innervation of frontalis muscle. Involuntary emotional movements and the tone of facial mu...
ENT
Ear
5c2666a3-14d5-40f7-90b2-554a8cdfed47
A young patients presented with loss of sensation in sole of foot with paralysis of medial side of plantar muscles of the foot, Most likely nerve involvement is
Common peroneal nerve
Deep peroneal nerve
Superficial peroneal nerve
Tibial nerve
3d
single
TIBIAL NERVE:- Root value:ventral division of ventral rami of L4,L5,S1,S2,S3 segments of spinal cord.Beginning: largest subdivision of sciatic nerve.Course: descends veically in popliteal fossa. It continues in back of leg as the neurovascular bundle with posterior tibial vessels. Lastly passes deep to flexor retinacul...
Anatomy
Lower limb
f03e4711-9b06-4b69-b05c-770c3aff7047
34-year-old patient has moderately severe new onset asthma, and physician gave him a selective b2 agonist inhaler. All of the following signs can be seen in this patient after taking the drug EXCEPT?
Tachycardia
Skeletal muscle tremor
Hypoglycemia
Hypokalemia
2c
multi
Tremor is a common b2 action, Beta 2 agonists increase the movement of K inside the cells, so these can result in hypokalemia. This action is the basis of use of salbutamol in treatment of hyperkalemia At high doses, selectivity is lost and therefore overdose of beta 2 agonists can result in tachycardia. Beta2 agonist ...
Pharmacology
Sympathetic System
310723c7-90f0-484d-9c65-13e85ca5f7f9
Features of vernal conjunctivitis are –a) Shield ulcerb) Horner–Trantas spotsc) Papillary hypertrophy d) Herbert pitse) Pannus
ab
bc
abc
bcd
2c
single
Conjunctival signs of spring catarrh .Palpebral form: Papillary hypertrophy, cobblestone appearance (Pavement stone appearance). Bulbar form: Dusky triangular congestion, gelatinous thickening around limbus, Horner - Tranta's spot. Corneal signs (vernal keratopathy) Punctate epithelial keratitis Ulcerative vernal ke...
Ophthalmology
null
93a2d226-d05f-44d0-a4fa-62b8b2636916
Total fluid secreted by salivary gland, stomach, pancrease and itestine in a day -
2000ml
4000ml
6500 ml
10000 ml
2c
single
Ans. is 'c' i.e., 6500 ml Daily water turnover (mL) in the gastrointestinal tractIngested 2000Endogenous secretions 7000Salivary glands1500 Stomach2500 Bile500 Pancreas1500 Intestine+ 1000 7000 Total input 9000Reabsorbed 8800Jejunum5500 Ileum2000 Colon+ 1300 8800 Balance in stool 200
Physiology
Secretory Functions of the Alimentary Tract
e41ff274-2a84-4adb-b888-2c1759628584
Most common radiosensitive ovarian tumour ?
Dysgerminoma
Granulosa cell tumour
Teratoma
Theca cell tumour
0a
single
Ans. is 'a' i.e., Dysgerminomao Dysgerminomas are extremely radiosensitive, and even those that have extended beyond the ovary can generally be controlled by radiotherapy.
Pathology
null
eae532f5-8db4-4bea-ae20-7977fabc8695
"Herald patch" is characteristic feature of -
Pityriasis rubra pilaris
Psoriasis
Lichen planus
Pityriasis rosea
3d
single
Ans. is 'd' i.e., Pityriasis rosea o Herald patch or mother patch is a characteristic feature of P. rosea.o P. rosea is a common scaly disorder, occuring usually in children and young adults (10-35 years). Characterized by round/oval pink brown patches with a superficial, centrifugal scale, distributed over trunk in a ...
Skin
Erythmato-Squamous and Lichenoid Eruption
3b45f0a8-8f4f-4173-9587-f2fb92bd6471
Shock lung is characterized by
Alveolar proteinosis
Bronchiolitis obliterans
Diffuse pulmonary haemorrhage
Diffuse alveolar damage
3d
single
ref Robbins 7/r p715,9/e p134 Harrison 17/e p1680_1681 The cellular and tissue effects of shock are essentially those of hypoxic injury (Chapter 1) and are caused by a combina- tion of hypoperfusion and microvascular thrombosis. Although any organ can be affected, brain, hea, kidneys, adrenals, and gastrointestinal tra...
Anatomy
General anatomy
d99bdc41-a942-4f38-b12d-aac28e388fe6
Most common muscle involved in Tropical pyomyositis
Biceps
Triceps
Quadriceps
Gluteus
2c
single
Tropical pyomyositis is caused by S.Aureus which mainly involves Quadriceps > Gluteus.
Microbiology
null
dec7f8a0-a2b6-4f34-9e99-8bab80009df9
Visual analog scale is a -
Pain scale
Pressure scale
Vision scale
Auditory scale
0a
single
Ans. is 'a' i.e., Pain scale Visual analog Scaleo The visual analogue scale or visual analog scale (VAS) is a psychometric response scale which can be used in questionnaires.o It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured,o When responding to a VAS item, res...
Psychiatry
Symptoms & Signs
938988e3-76c1-41b1-b020-5493af058160
Type of pneumonia in P. jiroveci:
Lobar pneumonia
Interstitial pneumonia
Bronchopneumonia
Any of the above
1b
multi
Ans. b. Interstitial pneumonia
Microbiology
null
c32ba701-cefd-4a4b-a22e-b630303a5c41
Which of the following neurotransmitter has an inhibitory control over the GnRH neurons before the onset of pubey?
Glycine
Glutamate
Gamma amino butyric acid (GABA)
Beta-endorphin
2c
single
Before the onset of pubey, the GnRH neurons are under the inhibitory control of GABA. Gamma amino butyric acid is a dominant inhibitory neurotransmitter in the hypothalamus. Inhibition of GnRH neurons by GABA is mediated Glutamergic neurons. A reciprocal innervations between GABAergic and Glutamergic neurons are found....
Physiology
null
4f4bbdf5-cd01-4ed4-81f1-180cbb2aa8f7
A middle aged female presents with chronic pain in right side of abdomen with intermittent fever. Clinical examination revealed mild hepatomegaly and hence a contrast enhanced CT abdomen was performed. Based on the imaging characteristics of this focal lesion the most likely diagnosis is?
Liver abscess
Hydatid cyst
HCC
Hepatic adenoma
1b
single
Ans. B. Hydatid cystThe Portal phase CT demonstrates a large cystic structure with a discrete wall, separated internal membranes and several 'daughter cysts'This is an infection of the liver with Echinococcus granulosus, a parasitic tapeworm presents worldwide and transmitted from sheep, foxes and other wild animals to...
Radiology
G.I.T.
fb865f28-72e2-4d53-ab73-361d218151af
Millard Gubler syndrome includes the following except
5th nerve palsy
6th nerve palsy
7th nerve palsy
Contralateral hemiparesis
0a
multi
Millard-Gubler syndrome (MGS) is one of the classical brainstem-crossed syndromes caused due to a unilateral lesion in ventral pons, manifesting as ipsilateral palsy of CN VI and VII with contralateral hemiplegia Ref Harrison20th edition pg 2234
Medicine
C.N.S
2178c430-5d6b-4d56-bd67-f41bc435991e
C. trachomatis is a well-known cause of venereal disease. This organism is also implicated in which of the following?
Classic trachoma infection
Sexually transmitted cardiac disease in adults
Perinatal retinitis
Middle-ear infection in young children
0a
multi
Trachoma has been the greatest single cause of blindness in the world. Chlamydia trachomatis is the most common cause of sexually transmitted disease in the United States and is also responsible for the majority of cases of infant conjunctivitis and infant pneumonia.
Microbiology
Bacteria
9cb6505c-e076-4b5f-b206-a4ffb3394aad
Prostaglandins are produced by ?
Neutrophils
Endothelium
Macrophages
All of the above
3d
multi
Ans. is 'd' i.e., All of the above
Pathology
null
90d5e93d-1095-49f8-8f38-1a7bd0a6ce7f
All of the following statements about Parvovirus B -19 are TRUE, EXCEPT:
DNA virus
Crosses placenta in only < 10% of cases
Can cause severe anemia
Can cause Aplastic crisis
1b
multi
Parvovirus B-19 causes a infection called Erythema infectiosum or Fifth disease. Around 50-70% cases are around 5-15 years of age. Transmission from mother to fetus is around 15-30%. It causes, anemia, aplastic crisis, rashes, ahralgia, rarely hydrops fetalis. Ref: Kliegman, Behrman, Jenson, Stanton (2008), "Nelson tex...
Microbiology
null
bb2a7aec-3661-45d1-b04d-dbdc827a1a3b
'Pie in the sky' visual field defect seen in lesions of:
Optic tract
Temporal coex
Optic chiasma
Occipital coex
1b
single
A. Left Hemianopia Left optic nerve lesion B. Bitemporal Hemianopia Optic chiasm lesion C. Right Nasal Hemianopia Outer optic tract lesion Internal carotid aery thrombus D. Right Homonymous Hemianopia Optic tract lesion E. Right Superior Quadrantanopia Meyer's Loop lesion Left temporal lesion F. Right Inferior Quadrant...
Medicine
JIPMER 2017
91ced434-5bf5-4549-be6c-0a89f3709f4f
What is true regarding Barret's esophagus:
Seen in females
Premalignant
Responds to conservative management
Squamous metaplasia is seen
1b
multi
Answer is B (Premalignant condition) Barret's oesophagus is a premalignant condition with increased risk of adenocarcinoma. Barret's esophagus is more common in males More common in males (Males > Females)0 More common in White (Whites > Blacks)e More common with increasing ageU Barret's metaplasia once established doe...
Medicine
null
35712a2e-6730-46c6-81ae-6cc1d4a2e601
Combined oral pill reduces the risk of:
Breast cancer
Ovarian cancer
Cervical cancer
Vaginal cancer
1b
single
null
Pharmacology
null
88b4d6b4-790c-40a1-997a-bb0d94d28ab9
Gas shadow in hea and vessels are seen in
IUD
Still bih
Aboion
Live IUGR
0a
single
Robe sign - the presence of a gas shadow within the hea or the greater vessels, seen in cases of fetal death in utero.It is a rare sign caused by postmoem blood degeneration, usually seen 1-2 days after death; and may be seen as early as 12 hours(Ref: Diagnostic Ultrasound by Carol M. Rumack, Stephanie R. Wilson, J. Wi...
Radiology
All India exam
cd73e9ab-24cb-48ad-ba16-d355b8cb219a
Structures passing through the centre of the cavernous sinus
Occulomotor nerve
Trochlear nerve
Maxillary nerve
Abducent nerve
3d
single
null
Anatomy
null
0b62ad34-9ae0-4aad-b129-76b16aff73d8
Latte's crust of blood stain is used to detect: NEET 14
Nature of stain
Detection species
Blood group
Secretor status
2c
single
Ans. Blood group
Forensic Medicine
null
002e3dba-a304-4b6f-b5ad-841c9772915e
The cause of fetal death in ectopic pregnancy is postulated as:
Vascular accident
Nutritional adequacy
Endocrine insufficiency
Immune response to mother
0a
single
Ans. is a, i.e. Vascular accidentRef Williams Gynae 1/e, p 158Ectopic pregnancy is the leading cause of early pregnancy related deaths.Most common cause of death in ectopic pregnancy is tubal rupture - severe hemorrhage - death.Ectopic pregnancy can have 2 outcomes:1. Tubal abortion - M/C outcome. It is most common out...
Gynaecology & Obstetrics
Ecotopic Pregnancy
2751c757-3052-4d6e-b50f-aca1f07102b4
When a stretch reflex occurs the muscles that antagonize the action of the muscle involved relaxes. This phenomenon is known as:
Inverse stretch reflex
Reciprocal innervation
Autogenic inhibition
Lenthening reaction
1b
single
Reciprocal innervation is a phenomenon in which, when a stretch reflex occurs the muscles that anotogonize the action of the muscle involved relaxes. The pathway mediating this effect is bisynaptic. Golgi bottle neurons (inhibitory interneurons) are involved in this phenomenon. Ref:Ganong's Review of Medical Physiology...
Physiology
null
95a54f5b-6f8e-4b73-81f4-1fb6ce8c95b1
Jaw tightness is typically seen in:
PAN
Coarctation of aoa
Giant cell aeritis
Wegner's Granulomatosis
2c
multi
Answer is C (Giant Cell Aeritis): Jaw Claudication (law Tightness) is a typical manifestation of Temporal aeritis or Giant cell aeritis.
Medicine
null
58493f13-b284-4c8b-aea8-ac91c6906bb4
Salpingitis/Endosalpingitis is best confirmed by:
Hysteroscopy and laparoscopy
X-ray
Hysterosalpingography
Sonosalpingography
0a
single
Ans. is a, i.e. Hysteroscopy and laparoscopyRef: Shaw 15th/ed, p451; William's Gynae 1st/ed, p74; Gynecology by Ostrzenski (Lippincott Williams 2(X)l/282); Dutta Gynae 6th/ed, p130Laparoscopy is considered the "gold standard". While it is the most reliable aid to support the clinical diagnosis but it may not be feasibl...
Gynaecology & Obstetrics
Sexually Transmitted Disease in the Female
4812d943-20cc-454d-ba06-36f3cfa8f1a1
Lymes disease all are true except
Borellia bourgdroferi replicates locally and invades locally
Infection progresses inspite of good humoral jmmunity
Polymorphonuclear lymphocytosis in CSF suggest meningial involvement
IgA intrathecally confirms meningitis
2c
multi
Polymorphonuclear leucocytosis in C.S.F. suggests meningeal involvement Spread of infection and immune response in Lyme disease Lyme disease is caused by Borrelia Burgdorferi. Borrelia burgdorferi is transmitted to humans the bite of ixodes tick vector. Borrelia burgdorferi is inoculated in the skin, where local replic...
Microbiology
null
cd310389-1769-4e19-ae9d-7147dbba43a8
Approximate time, at the end of which the quantity of ATP within ischemic cardiac myocytes is reduced to 10% of the original is
<2 minutes
10 minutes
20 minutes
40 minutes
3d
single
Metabolic changes slow as the duration of ischemia increases. Irreversibly injured myocytes exhibit (a) very low levels of ATP (less than 10% of control); (b) cessation of anaerobic glycolysis; (c) high levels of H+, AMP, INO, lactate, and alpha GP; (d) a greatly increased osmolar load; (e) mitochondrial swelling and f...
Pathology
General pathology
28d9381a-fe86-4e2c-83c4-b3e91be76174
Aluminium phosphide poisoning - all true except
subendocardial infarction
produces phosphine gas
oesophageal stricture
inhibits cytochrome a oxidase
3d
multi
inhibits cytochrome a oxidase Aluminium phosphide produces phosphine gas on coming in contact with moisture which inhibits cytochrome c oxidase (and not cytochrome a oxidase). Sub-endocardial infarction and esophageal strictures both have been described with ALP poisoning (Ref: various journals on web) Aluminium phosph...
Forensic Medicine
null
14879dd5-20b7-461e-ad63-febe0162ea20
The small intestine secretes various triglyceride-rich lipoproteins, but the liver secretes only
Chylomicrons
VLDLs
LDLs
HDLs
1b
multi
Although both chylomicrons and VLDLs are triglyceride-rich lipoproteins, the liver, unlike the small intestine, produces only VLDLs. LDLs and HDLs are not triglyceride-rich lipoproteins. Chylomicron remnants are generated in the circulation by the metabolism of chylomicrons.
Pathology
All India exam
8ffe0336-2c8c-4875-a000-57fda3308b3b
Snyder's test measures
Amount of acid produced
Number of new caries lesion
Buffering action of saliva
Antibiotic activity of saliva
0a
single
null
Dental
null
60147ab1-bfb5-4f1e-b85e-6c5cec69444b
Features not seen in Cushing's Syndrome is :
Hypoglycemia
Hypeension
Frank psychosis
Hypokalemia
0a
single
Answer is A (Hypoglycemia): Cushing's syndrome is characterised by Hy perglycemia. Increased hepatic gluconeogenesis and insulin resistance causes increase in blood glucose. Hypeension is common, & emotional changes may be profound, ranging from irritability & emotional liability to severe depressions, confusion or eve...
Medicine
null
e4f44e40-d163-49f9-9291-508de06c13ab
Fulminant hepatitis is most commonly associated with which type of hepatitis -
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
1b
single
Ans. is 'b' i.e., Hepatitis B Fulminant hepatits* The most feared complication of viral hepatitis is fulminant hepatitis (massive hepatic necrosis); fortunately, this is a rare event.* Fulminant hepatitis is primarily seen in hepatitis B and D, as well as hepatitis E, but rare fulminant cases of hepatitis A occur prima...
Medicine
Infection
019d5e6b-3ee0-4586-b24b-6e8b6bd4d3fe
Blood samples for glucose estimation are collected in fluoride bulbs/tubes as fluride prevents glycolysis byinhibition of
Enolase
Aldolase
Glucokinase
Phosphofructokinase
0a
single
Ans. a (Enolase) (Ref. Harper's Illustrated 26th ed., 137; 27th/Ch. 18)ENOLASE# The step of glycolysis catalyzed by enolase involves dehydration, forming phosphoenolpyruvate.# Enolase is inhibited by fluoride.- To prevent glycolysis in the estimation of glucose, blood is collected in tubes containing fluoride.# The enz...
Biochemistry
Carbohydrates
4ccd65c3-6daf-4481-9990-d954037a2684
Which is a communicating hydrocele?
Vaginal hydrocele
Hydrocele of the cord
Infantile hydrocele
Funicular hydrocele
3d
single
Funicular hydrocele Communicating hydrocele: (a) Funicular hydrocele, and (b) Congenital hydrocele. a. Funicular Hydrocele: Processus vaginalis remains patent up to the top where it is shut off from the tunica vaginalis. Diagnostic features: (i) The swelling is inguinal rather than scrotal. (ii) The test is it can be f...
Surgery
null
a46a0529-1fba-4d04-ae8b-f932892359f3
Compound odontoma shows on a radiograph as
Supernumerary teeth
Radiolucent and radiopaque areas
Masses of calcified areas
Distinguishable tooth -Like structures
3d
single
null
Pathology
null
ac019b99-9105-4cf9-8542-46e8229e88de
1st evidence of calcification of Maxillary deciduous Lateral incisor occurs
14 wk IU
16 wk IU
17 wk IU
15 wk IU
1b
single
null
Dental
null
98c1ec0d-c674-409d-844c-16a0081eda59
Which of the following structures is most significant in resisting hyperextension of the hip joint?,
Pubofemoral ligament
Ischiofemoral ligament
Iliofemoral ligament
Gluteus maximus muscle
2c
single
The Iliofemoral Ligament resist both hyperextension and lateral rotation at the hip joint. The Pubofemoral ligament reinforces the joint inferiorly and limits extension and abduction. The Ischiofemoral ligament reinforces the joint posteriorly and limits extension and medial rotation. The Gluteus Maximus muscle extends...
Anatomy
Bones Joints and Ligaments
757ad506-4f62-489d-8eb4-56b4501326e5
Rhinophyma occurs as complication of
Acne vulgais
Acne rosacea
Psoriasis
Plicinphigus
1b
single
Rosacea:-Chronic skin infection characterised by symptoms of facial flushing and a spectrum of signs including erythema, telangiectasia,coarseness of skin and inflammatory papulopustular lesion.Features:-1. Red papules and pustules on nose ,forehead,cheeks and chin.2. Frequent flushing 3. Aggravated by sun exposure,foo...
Dental
Photosensitive disorders
e5070298-ba70-4797-ba07-d1f277f7f5ad
In CuT 200, the number stands for:
SurfaceAreaofCopper
Weight of Cu in microgram
Weight of Cu in milligram
Effective half life in weeks
0a
single
Ans: A (Surface...) "The number included in the names of the devices refer to the surface area (in sq, mm) of the copper on the device. Park 21st/459 IUDs: Review of Facts# CuT-200 B being used in India , under the national family welfare programme,Later CuT 380A is introduced in the programme.# Studies have shown that...
Social & Preventive Medicine
Family Planning