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135
d65ade7a-0f33-40a8-a229-e945717f69ee
Drug used for Buerger's disease:
Xanthinol nicotinate
Propranolol
CCBs
All of the above
0a
multi
Xanthinol Nicotinate Xanthinol nicotinate (or xanthinol niacinate or complamina) is a vasodilatorQ. It is a combination of xanthinol and niacin (nicotinic acid) This vasodilator is used in the treatment of Raynaud's phenomenon and Buerger's disease. All other forms of pharmacologic treatment have been generally ineffec...
Surgery
Aerial disorders
dbe167ed-95b1-48cd-890f-1846f9375bea
True about centchroman are all, EXCEPT :
It is synthetic non -- steroidal contraceptive
The only side effect is oligomenorrhoea
Safe in liver disease
Can be used as post -- coital pill
2c
multi
Safe in liver disease
Gynaecology & Obstetrics
null
09b74a26-896d-429c-8765-c8bb07819f3b
Alcohol anti-craving agents are all, except: AIIMS 09
Lorazepam
Clonidine
Acamprosate
Naltrexone
0a
multi
Ans. Lorazepam
Forensic Medicine
null
1d9fb803-31b6-4c88-b8a3-ec2a7a806839
No effect on hea
Chloroform
Ether
Methoxyflurane
Halothane
1b
single
B i.e. Ether
Anaesthesia
null
8b5168d2-3bdb-46bf-a8ae-74a30027b245
In type I hypersensitivity, the mediators is
IgE
IgG
IgM
IgC
0a
single
(IgE) (161-AN 7th) (202-206-CP)Types of hypersensitivity reactions and their featuresType of reactionClinical syndromeMediatorsType I: IgE1. Anaphylaxis2. Atopy P. K. reactionIgE, histamine and other pharmacological agentsType II: Cytolytic and CytotoxicAntibody-mediated damage- thrombocytopenia-agranulocytosis, hemoly...
Microbiology
Immunology
0524a605-a4ee-4ae8-b71e-0b306a28d15e
Microvesicular type of fatty liver is Seen in the following except
Acute fatty liver of pregnancy
Alcoholic liver disease
Reye's syndrome
Phosphorus intoxication
1b
multi
Fatty liver disease means you have extra fat in your liver. You might hear your doctor call it hepatic steatosis. Heavy drinking makes you more likely to get it. Over time, too much alcohol leads to a buildup of fat inside your liver cells. This makes it harder for your liver to work. But you can get fatty liver diseas...
Pathology
G.I.T
3fc9309c-3954-42a1-8d48-db096fa64252
Northern blot is used for identification of: (Repeat)
RNA
DNA
Protein
Antibodies
0a
single
Ans: A (RNA) Ref: Ananthanarayan R, Paniker CKJ. Textbook of Microbiology. 8th Edition. Hyderabad: Universities Press; 2009. Pg. 69Explanation:Southern blotting:The highly sensitive technique for identifying DNA fragments by DNA-DNA hybridisation is called Southern blotting, after EM Southern who devised it. This techn...
Microbiology
Immunology
40220284-efb3-4c4e-b5e1-506438ce3cdb
Snowman's heart sign on chest X-ray is seen in -
Ebstein anomaly
Total anomalous pulmonary venous connection (TAPVC)
Tetrology of Fallot
Transposition of great vessels
1b
multi
Ans. is 'b' i.e., Total anomalous pulmonary venous connection (TAPVC) o "Snowman" or "figure of 8" or "cottage loaf sign" is characteristic of supracardiac TAP VC.Cardiac configrationo "Boot-shaped" heart (cour en sabot)Fallot's tetralogyo "Egg on side" heart ("egg in cup" heart)Transposition of great arterieso "Egg in...
Radiology
Cardiac and Pericardiac Imaging
e580e119-d0e3-47e3-b1d4-4e6519ae1c02
Continuous Renal Replacement Therapy is initiated in which of the following phases of Acute Renal Failure:
Initiation
Maintenance
Diuretic Phase
Recovery Phase
1b
single
Answer is B (Maintenance) Continuous Renal Replacement Therapy should be initiated during the Maintenance phase (Oliguric Phase) of Acute Renal Failure. Maintenance phase refers to the phase of Renal Failure in which the renal injury becomes established. It is also known as the Oliguric Phase. During this phase the GFR...
Medicine
null
648aca31-f7e3-446e-adcb-4623c1ae3240
True about montoux is -
False negative in fulminant diseases
If once done, next time it is always positive
Results are given in terms of positive & negative
Indurations given in terms of length & breadth
0a
multi
Ans. is 'a' i.e., False negative in fulminant disease . A positive tuberculin test indicates hypersensitivity to tuberculoprotein, it may be due to : - Active infection - Subclinical infection - Past infection - BCG vaccination . In overwhelming tuberculosis (fulminant cases) due to depressed cellular immunity montoux ...
Microbiology
null
d00f4589-370b-4e3a-a127-5baba6e828c4
Which of the following receptors is activated by acetylcholine and blocked by atropine.
Nicotinic
Muscarinic
Alpha 1 and 2
Beta 1 and 2
1b
single
null
Pharmacology
null
c7fecf9f-a7be-4f63-9649-c230d8cd426f
Embolectomy should be done within
4 hours
6 hours
8 hours
10 hours
1b
single
Embolectomy should be done within 6 hours as after 6 hours, irreverside changes occur.
Surgery
null
44f32545-3ae7-48a3-bed3-ac10255d0ab9
Adverse effect of clozapine:
Hypeension
Sialorrhea
Extrapyramidal S/E
Neuroleptic malignant syndrome
1b
single
B i.e. Sialorrhea
Psychiatry
null
dcda1202-699d-4aac-945a-605e85b2fb95
Rough and Irregular surface produced on the impression is because of?
Improper application of pressure during impression making
Air incorporated during mixing
Too rapid polymerization
Presence of moisture in impression area
2c
single
null
Dental
null
b43198f1-8a92-4411-b3ab-4b495873c4ea
A 58 year old male presents with fatigue, abdominal pain and bloody stools. Colonoscopy reveals a mass in the descending colon. For surgical removal of the mass, ligation of which of the following arteries is required?
Superior mesenteric artery
Inferior mesenteric artery
External iliac artery
Internal iliac artery
1b
single
Answer: b) Inferior mesenteric artery (SABISTON 19th ED, P-1299; SCHWARTZ 10TH ED, P-1187)Left Colectomy.For lesions or disease states confined to the distal transverse colon, splenic flexure, or descending colon, a left colectomy is performed.The left branches of the middle colic vessels, the left colic vessels, and t...
Surgery
Small & Large Intestine
399f3276-a466-484c-87a1-7b02932035bc
All of the following statements regarding Clostridium perfringens are true, EXCEPT:
It is the commonest cause of gas gangrene
It is normally present in human faeces
The principal toxin of C. perfringens is the alpha toxin
Gas gangrene producing strains of C. perfringens produce heat resistant spores
3d
multi
Spores of clostridium perfringens are killed within 5 minutes by boiling, it is also killed by autoclaving at 121 degree Celsius for 15 minutes. But spores of clostridium perfringens which produce food poisoning are heat resistant. Clostridium perfringens produces multiple exotoxins and is classified into five types (A...
Microbiology
null
866ff8e3-87ce-4cfa-848e-6dccf3ca929e
The cardiac jelly formed around the heart tube during early development, contributes to the formation of:
Pericardium
Mesocardium
Myocardium
Endocardium
3d
single
Ans. is D. The most appropriate answer to this question is actually endocardial cushion.
Anatomy
Cardiovascular System
c08b0520-376e-40fa-9829-37549138c60c
True about HIV epidemiology -
Children rarely affected
<10% of HIV infected person progress to AIDS
Southern africa have 72% of total global burden
Seminal secretion is more infectious than vaginal secretion
0a
multi
Key facts about Epidemiology of HIV infection Reservoir: Cases and carriers Source: Virus is in greatest concentration in blood, seen and CSF (Lower concentrations in tear, saliva, breast milk, urine, cervical and vaginal secretions) Children under 15 years make only 3% cases Basic modes of transmission Sexual Blood an...
Social & Preventive Medicine
Communicable diseases
5dbdfee3-5bdf-4f73-ae33-b0298165dccd
who gave the stage of trust versus mistrust
seligman
erikson
lorenz
bleuler
1b
single
ERIC ERIKSON ERIC ERIKSON gave the psychosocail stages of development There are 8 psychosocial stages A person has to succesfully pass one stage to move to the next stage If he gets arrested in one stage he may develop some disorders Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pf no. 485
Anatomy
Treatment in psychiatry
e9234440-4543-4250-bb0b-75284b5ff71f
Which of the following statements about Xanthogranulomatous pyelonephritis is not true ?
Foam cells are seen
Associated with tuberculosis
Yellow nodules are seen
Giant cells may be seen
1b
multi
Ans. is 'b' i.e., Associated with tuberculosisXanthogranulomatous pyelonephritis o Xanthogranulomatous pyelonephritis is a chronic infective condition of the kidney associated with chronic bacterial infection.o The most common organism implicated in causation is proteus followed by E coli (not tuberculosis). o Most of ...
Pathology
null
b90e68fd-292e-46e3-a51d-20c7e13803ea
A 1.5 year old female is brought to the clinic with complaints of excessive enlargement of head, intolerance to feeds and severe malnourishment. MRI imaging was suggestive of a medulloblastoma causing obstructive hydrocephalus. Which of the following is an example of irrational manattem,-the patient?
Craniotomy and sub-total excision of the tumour. Surgeon leaves the layer of the tumour adherent with colliculus
First ventirculoperitoneal shunt was done
CCNU and vincristine were given as chemotherapy
Radiotherapy 35-40 Gy was given to the whole craniospinal axis
3d
single
Ans. d. Radiotherapy 35-40 Gy was given to the whole craniospinal axis
Pediatrics
null
ded3964c-409d-4722-92f8-703f0f2e6e7e
Polysaccharides are
Polymers
Acids
Proteins
Oils
0a
single
Polysaccharides are polymers of monosaccharides. They are of two types- homopolysaccharides that contain a single type of monosaccharide (e.g., starch, insulin, cellulose) and heteropolysaccharides with two or more different types of monosaccharides (e.g., heparin, chondroitin sulfate).. Ref: Biochemistry by U. Satyana...
Biochemistry
Metabolism of carbohydrate
0024f7d2-17f6-40ba-b71b-57c2024fa8d2
Which of these need both V and X factors-a) Hemophilus influenzaeb) H. ducreic) H. paraphrophilusd) H. aegyptiuse) H. haemolyticus
ade
bde
abd
ad
0a
multi
null
Microbiology
null
915ad4c1-bf13-40b9-a1e6-734369acb4d5
What is seen in neurogenic shock ?
Bradycardia and hypotension
Tachycardia and hypotension
Bradycardia and hypetension
Tachycardia and hypetension
0a
single
Neurogenic shock is a distributive type of shock resulting in low blood pressure, occasionally with a slowed hea rate, that is attributed to the disruption of the autonomic pathways within the spinal cord. It can occur after damage to the central nervous system, such as spinal cord injury and traumatic brain injury. Re...
Medicine
Miscellaneous
e3f28754-e7bc-429a-90aa-feb6befea9a2
Combined oral pills protect the woman against all except -
Menorrhagia
Benign breast disease
Pelvic inflammatory disease
Venous thromboembolism
3d
multi
Ans. is 'd' i.e., Venous thromboembolism
Social & Preventive Medicine
null
9f9bab31-201c-46e5-b90e-68eb19e05d0d
Poor prognostic indicator in ALL -
Age < 2 year
TLC 4000-10,000
Presence of testicular involvement at presentation
Presence of blasts in peripheral smear
0a
multi
Ans. is 'a' i.e. Age < 2 year
Pathology
null
1eb3a07c-0761-4109-b442-1df43d6381ef
Plasma ceruloplasmin alpha 2 globulin is a
alpha 1 globulin
alpha 2 globulin
beta 1 globulin
beta 2 globulin
1b
single
null
Physiology
null
821ccf4a-0bc6-4609-9739-8a57449cc17f
Vogt Koyanagi Harada syndrome is -
Cataract
C.N.S. tumour
Uveitis
Polycystic kidney
2c
single
Ans. is 'c' i.e., UveitisClinical manifestations of Vogt Kavanadi Harada syndromeOccular involvementC.N.S. involvementAuditory manifestationCutaneous manifestationOccular involvementB/L panuveitis ino Meningismuso Hearing losso VitiligoB/L panuveitis inassociation with serouso Headacheo Tinnituso Alopeciaassociation w'...
Medicine
Eye
7ec6f55a-a1be-4320-8b2d-c7d3964a9cd3
Which of the following ultrasound marker is associated with greatest increased risk for Trisomy 21 in fetus?
Echogenic foci in hea
Hyperechogenic bowel
Choroid plexus cysts
Nuchal edema
3d
single
Ans. Nuchal edema
Radiology
null
da8fa56e-18b4-4702-b11d-1ce1652710a7
Cyanide affects respiratory chain by
Non-competitive reversible inhibition
Competitive reversible inhibition
Suicide irreversible inhibition
Non-competitive irreversible inhibition
3d
single
The toxicity of cyanide is due to its inhibitory effect on the terminal cytochrome which brings cellular respiration to a standstill. The inhibitor usually binds to a different domain on the enzyme, other than the substrate binding site. Since these inhibitors have no structural resemblance to the substrate, an increas...
Biochemistry
Enzymes
952f9b45-e625-4c8c-9094-85977dd21b8e
Presence of it indicates remote contamination of water
Streptococci
Staphalococci
Clastridium pertringes
Nibrio
2c
single
null
Social & Preventive Medicine
null
5b674035-82a3-4593-8b06-636d644d9da4
Mercury affects which part of the kidney -
PCT
DCT
Collecting duct
Loop of Henle
0a
single
Ans. (a) PCT(Ref: Robbins 9th/pg 928; 8th/pg 938)Nephrotoxic AKI*Caused by Gentamicin, radiographic contrast agents, heavy metals (eg mercury), organic solvents (eg CCl4 ).*Extensive necrosis along mainly proximal convoluted tubule (PCT) & ascending limb of Henle's loop.*On histologic examination, non-specific tubular ...
Pathology
Kidney
4784b4a0-3e02-4726-8621-dc15e6b39e3b
A 30 year old lady is to undergo surgery under intravenous regional anesthesia for her left 'trigger finger'. Which one of the following should not be used for patient?
Lignocaine
Bupivacaine
Prilocaine
Lignocaine + ketorolac.
1b
single
B i.e. Bupivacaine
Anaesthesia
null
317109c4-c462-41bd-8418-b7f1f0cbb633
One primary oocyte forms how many ovum/ova
1
2
3
4
0a
single
Observe that whereas one primary spermatocyte gives rise to four spermatozoa, one primary oocyte forms only one ovumHuman embryology Inderbir Singh&;s Tenth edition Pg 23
Anatomy
General anatomy
8678449c-ba36-4d30-b7c9-0cd10161a980
The age by which most of the normal babies know their gender is
1 year
2 years
3 years
4 years
2c
single
<p>. Developmental milestones:- GROSS MOTOR DEVELOPMENT: 2 months: Holds head in plane of rest of the body when held in ventral suspension. In prone position in bed, the chin lifts momentarily. 3 months:lift head above the plane of the body. Head control stas by 3 months and fully developed by 5 months. 4 months:Remain...
Pediatrics
Growth and development
c097ad16-73b2-420c-8ead-ed9e90bfec34
True about nucleosome
Use only one type of histone protein
Each complex is separated from each other by non histone proteins
Regular repeating structure of DNA & histone proteins
Reflect small nucleus
2c
multi
In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and playing a role in gene regulation. Without histones, the unwound DNA...
Biochemistry
Metabolism of nucleic acids
761d031c-0374-4bf3-a46f-d4e076f8055e
A 64 year old hypertensive obsese female was undergoing surgery for fracture femur under general anaesthesia. Intra-operatively her end-tidal carbon dioxide decreased to 20 from 40 mm of Hg, followed by hypotension and oxygen saturation of 85%. What could be the most probable cause?
Fat embolism
Hypovolemia
Bronchospasm
Myocardial infarction
0a
single
"Arterial blood gas analysis reveals hypoxemia and hypocapnia, with subsequent metabolic acidosis in severe pulmonary embolism. During anaesthesia, end tidal CO2 concentration may fall dramatically because of increased dead space and reduced cardiac output". _________ Anesthesia & Intensive care Note : Fat embolism ca...
Orthopaedics
null
f5bda2fd-4fea-4d2f-a8dd-d82652a8a70c
Which of the following drugs is taken during the first pa of the meal for the purpose of delaying absorption of dietary carbohydrates?
Acarbose
Glipizide
Metformin
Exenatide
0a
single
Acarbose is alpha glucosidase inhibitor. It inhibits the breakdown of complex carbohydrates to simple carbohydrates and thus they decrease the absorption. Glipizide is second generation sulphonylurea which helps in secretion of insulin. Metformin is biguanide which decrease the synthesis of glucose. Exenatide is GLP-1 ...
Pharmacology
Pancreas
ccaf0db5-f94b-484c-a030-dcba9337654b
Test for tight iliotibial band is
Ober's test
Osber's test
Simmond's test
Charnley's test
0a
single
OBER&;S TEST:Used in physical examination to identify tightness of iliotibial band. During the test ,the patient lies on his side with the unaffected leg on the bottom with their shoulder and pelvis in line. The knee may extended or flexed to 90 or 30 degrees.The hip is maintained in slight extension.The test leg is ab...
Orthopaedics
Bony dysplasia and soft tissue affection
6413275e-0cae-4aac-ab68-ac3c51233325
The antiepileptic drug effective in Lennox-Gastaut syndrome is:
Lamotrigine
Gabapentin
Tiagabine
Primidone
0a
single
Lamotrigine is the most effective drug among the given options. Ref: Harrisons principles of internal medicine, 18 th edition ; Page : 3263, Table : 369/9.
Medicine
null
fb22bfc1-6edc-4099-9d59-5ab1aec761e2
Ten days after an exploratory laparotomy and lysis of adhesions, a patient, who previously underwent a low anterior resection for rectal cancer followed by postoperative chemoradiation, is noted to have succus draining from the wound. She appears to have adequate source control--she is afebrile with a normal white bloo...
Previous radiation
Previous chemotherapy
Recent surgery
History of malignancy
0a
single
Factors that predispose to fistula formation and may prevent closure include foreign body, radiation, inflammation, epithelialization of the tract, neoplasm, distal obstruction, and steroids.Factors that result in unhealthy or abnormal tissue surrounding the enterocutaneous fistula decrease the likelihood of spontaneou...
Anaesthesia
Preoperative assessment and monitoring in anaesthesia
35d38266-5b7a-4c72-a7cb-193ceed76f3e
All are causes of hypertension with hypokalemia except,
Bilateral renal artery stenosis
End stage renal disease
Primary hyperaldosteronism
Cushing disease
1b
multi
Ans. is 'b' i.e. End stage renal disease Hypertension with HypokalemiaHigh reninRenal artery stenosisAccelerated hypertensionRenin-secreting tumorEstrogen therapyLow reninPrimary aldosteronismAdenomaHyperplasiaCarcinomaAdrenal enzyme defects1 1b- Hydroxylase deficiency17a- Hydroxylase deficiencyCushing's syndrome or di...
Medicine
Electrolyte
147e51b1-897e-41db-82dc-a08be5d897c0
All are autosomal dominant except -
Familial hypercholesterolemia
Hereditary spherocytosis
Acute intermittent parphyria
Phenylketonuria
3d
multi
Phenylketonuria (PKU) is an inborn error of metabolism that results in decreased metabolism of the amino acid phenylalanine.] Untreated PKU can lead to intellectual disability, seizures, behavioral problems, and mental disorder. It may also result in a musty smell and lighter skin. Babies born to mothers who have poorl...
Pathology
General pathology
273dda97-7fed-4d82-b195-833c128a1a63
Primary structural defect of an organ is termed -
Malformation
Disruption
Deformation
Association
0a
single
Ans. (a) Malformation(Ref: Robbins 9th/pg 452)Malformation refers to primary structural defect of an organ due to intrinsically abnormal developmental process (multifactorial); Eg Anencephaly, Congenital heart defects
Pathology
Disease of Infancy & Childhood
1be6340e-dfa4-4824-a04a-45685b6a3538
Major basic protein is an important constituent of which leucocyte:
Neutrophil
Eosinophil
Basophil
Lymphocyte
1b
single
null
Physiology
null
e606ba31-702f-4b9e-b881-573e88acc7eb
First investigation done for abnormal uterine bleeding in reproductive age group is _______
Ultrasonography transabdominal
Pap smear
Urine Beta HCG
Ultrasonography transvaginal
2c
single
The first investigation for abnormal uterine bleeding is Urine Beta HCG to rule ouut pregnancy. Abnormal Uterine Bleeding(AUB): is a common and debilitating condition. Chronic AUB was defined as &;bleeding from the uterine corpus that is abnormal in volume, regularity and/or timing that has been present for the majorit...
Gynaecology & Obstetrics
Disorders of menstruation
81cd9759-0f73-42e8-80b2-6fad72c0be57
Female sterilization is absolutely contraindicated in:
Hea disease
Diabetes mellitus
Hypeension
None of the above
3d
multi
There is no absolute medical contraindication for female sterilization. Also remember, : FEMALE STERILIZATION MALE STERILIZATION - Married - Married - 22-49 yrs old female - 22-60 yrs old male - >= 1 child - >= 1 child - No past history in self/ spouse sterilization - No past history in self/ spouse sterilization - MIN...
Social & Preventive Medicine
Other FP Methods and New Initiatives in Family Planning
acf4efba-a38c-4bf9-a87c-22861c5a7619
Causes of biliary tract carcinoma after ingesting infected fish -
Grathostoma
Angiostrongylus cantonens
Clonorchis sinensis
H. Dimunata
2c
single
In most cases the disease tends to remain low grade and chronic producing only minor symptoms of abdominal distress,intermittent diarrhea and liver pain or tenderness.C.sinensis has been linked to bile duct carcinoma.It is mostly observed in areas where chlonorchiasis is endemic (refer pgno:126 baveja 3 rd edition)
Microbiology
parasitology
35300445-fc06-4e52-bc1e-4befe09b76ae
Joint not involved in Rheumatoid ahritis according to 1987 modified ARA criteria?
Knee
Ankle
Tarsometatarsal
Met at arsophalangeal
2c
single
Tarsometatarsal The 1987 Revised Criteria for the Rheumatoid ahritis 4 out of 7 criteria are required to classify a patient as having rheumatoid ahritis Patients with 2 or more clinical diagnoses are not excluded. 1.Morning stiffness: morning stiffness in and around joints lasting at least 1 hour before maximal improve...
Surgery
null
aefcd39e-dcc9-4f29-89db-abb4c7922853
Antibody transfer mother to fetus -
IgG
IgM
IgD
IgA
0a
single
Ans. is 'a' i.e., IgG
Microbiology
null
685d2f83-c9ce-40b4-90c4-0acd533bb8d5
Hydrocephalus in infant is best diagnosed by
USG cranium
CT scan head
Encephalogram
Lumbar-puncture
0a
single
Ans. a (USG cranium). (Ref. Grainger, Diagnostic Radiology, 4th ed., 2469)Cranial ultrasound of Infants# USG cranium is best method to diagnose hydrocephalus through the anterior and posterior fontanalles.# Progression of hydrocephalus can be estimated by comparison with previous studies.# USG is also helpful in follow...
Radiology
Nervous System
2e717f2e-854c-4a1d-9bff-06fe78da7b1e
Non-Inflammatory arthritis is
Rheumatoid arthritis
Reiter's syndrome
Gonococcal arthritis
Osteo-arthritis
3d
single
null
Orthopaedics
null
066df44b-90cf-4603-a51b-83b306c71ca8
TRUE/FALSE statements about radial nerve is/are: 1. Branch of posterior cord 2. Nerve of extensor compament of forearm 3. Arise from C5 - T1 4. Anterior interosseous nerve is a branch of it 5. Supply skin of extensor compament
1,2,3 true & 4,5 false
1,2,3,4 true & 5 false
1,2,3,5 true & 4 false
All are true
2c
multi
Radial nerve is the largest branch of the posterior cord of the brachial plexus with a root value of C5 - C8 and T1. The radial nerve is commonly injured in the region of the spiral groove. this result in the wrist drop and sensory loss over a narrow strip on the back of forearm, and on the lateral side of the dorsum o...
Anatomy
null
81df78f3-28c4-4f25-bb89-94571ead91bf
Which is not a common enzyme for glycolysis and gluconeogenesis?
Aldolase
Glucose-6-phosphatase
Phosphoglycerate mutase
Phosphoglycerate kinase
1b
single
Seven of the reactions of glycolysis are reversible and are used in the synthesis of glucose by gluconeogenesis. Thus, seven enzymes are common to both glycolysis and gluconeogenesis : (i) Phosphohexose isomerase; (ii) Aldolase; (iii) Phosphotriose isomerase, (iv) Glyceraldehyde 3-phosphate dehydrogenase; (v) Phosphogl...
Biochemistry
null
31fe7b54-b8d4-4012-a442-e0a6de1a1518
Hepatotoxic agent is -
Halothane
Ketamine
N2O
Ether
0a
single
Ans. is 'a' i.e., Halothane o Halothane is the most hepatotoxic anesthetic.o Hepatotoxic anaesthetic agents are :1. Chloroform2. Halothane3. Carbon tetrachloride4. Trichloroethylene5. MethoxyfluraneRemembero Nitric oxide is least potent inhalation agent (MAC - 105%).o Halothane is most potent inhalation agent-MAC - 0.7...
Anaesthesia
Anesthesia for Liver Disease
a03a141d-c3b3-499d-9c9f-7ab5090be664
Which of the following is the "Least common" complication of measles-
Diarrhoea
Pneumonia
Otitis media
SSPE
3d
single
<p>measles complications:- Most common complications are 1. Measles associated diarrhoea. 2. Pneumonia 3. Otitis media 4. Respiratory complications Pneumonia is the most life threatening complication. Pulmonary complications account for more than 90% of deaths due to measles. Neurological complications:- 1. Febrile con...
Social & Preventive Medicine
Communicable diseases
053c2e27-a695-4e2c-b003-2d02c43e4c6f
COX pathway is inhibited by :
Aspirin
Indomethacin
Diclofenac
All of these
3d
multi
Aspirin inhibits COX irreversibly by acetylating one of its serine residues; return of COX activity depends on synthesis of fresh enzyme. Other NSAIDS like indomethacin, diclofenac etc are competitive and reversible inhibitors of COX, return of activity depends on their dissociation from the enzyme which in turn is gov...
Pharmacology
null
b59dc2c9-8a3a-435f-84f5-6dac3261bbf3
Poor prognostic factor in chizophrenia is:
Acute onset
Family history of affective disorder
Middle age
Past history of schizophrenia
3d
single
Past history of schizophrenia
Psychiatry
null
4b195c3e-3bba-4c0d-b70b-0f54c78c7d6c
In ETC cmplex-4 is inhibited by all except -
CO
CN-
H2S
BAL
3d
multi
Ans. is 'd' i.e., BAL o Rotenone inhibits complex I (NADH-CoQ reductase).Inhibitors of electron transport chain-o Inhibitors of respiratory chain may be divided into three groups : -Inhibitors of electron transport chain properThese inhibitors inhibit the flow of electrons through the respiratory chain. This occurs at ...
Biochemistry
Respiratory Chain
29205d8f-9b6e-424d-862a-470f1f439941
Which cranial nerve(s) is/are not involved in "Locked in syndrome"?
9
10
11
12
2c
single
Locked-in Syndrome: A pseudo-coma state in which an awake patient has no means of producing speech or volitional movement Retains voluntary veical eye movements and lid elevation Pupils are normally reactive. Aphonic because of the involvement of pyramidal fibers Involvement of medulla leads to 9th, 10th, 12th nerves. ...
Medicine
Stroke and TIA
ec6c978a-dca9-41b7-abe1-a06f0ba06389
True regarding scrum pox is all except
Common in rugby players
Caused by varicella zoster virus
Acyclovir is treatment
Vesicular Lesions and fever seen
1b
multi
Serum pox is caused by HSV - type I.
Surgery
null
ba65970e-96d2-48a2-a1f7-44b0b1a9dc7c
All of the following syndromes are seen with obesity except:
Prader - Willi syndrome
Cohen syndrome
Laurence Moon - Biedl syndrome
Carcinoid syndrome
3d
multi
Cohen syndrome - Cohen syndrome is Paternal inheritance always associated with obesity Carcinoid syndrome - Excess of 5 HT derivatives : Serotonin increase leads to secretory diarrhea & will Result in weight loss Prader willi syndrome - caused by deletion of chromosome 15 Sho stature, obesity, inappropriate laugh so ca...
Medicine
FMGE 2017
dfb2a593-3762-4073-86bf-65bc2a8e689a
A case of injury to right brow due to a fall from scooter present with sudden loss of vision in the right eye.The pupil shows absent direct reflex but a normal consensual pupillary reflex is present. The fundus is normal. The treatment of choice is-
Intensive intravenous corticosteroids as prescribed for spinal injuries to be instituted within six hours
Pulse methyl Prednisolone 250 mg four times daily for three days
Oral Prednisolone 1.5 mg/kg body weight
Emergency optic canal decompression
0a
multi
Sudden loss of vision, absent Ipsilateral direct light reflex and normal ipsilateral consensual light reflex suggest the diagnosis of optic nerve injury. Within 8 hours of injury megadose of iv steroid (methylprednisolone) should be given. If there is no response or deterioration, optic canal decompression should be do...
Ophthalmology
null
83b524ec-a747-489a-8021-3a2d96f64b2b
Cauliflower ear is associated with:
Otomycosis
Hematoma
Otosclerosis
None of the above
1b
multi
A patient with an auricular hematoma usually presents with an edematous, fluctuant, and ecchymotic pinna, with loss of the normal cailaginous landmarks. Failure to evacuate the hematoma may lead to cailage necrosis and permanent disfigurement known as "cauliflower ear."
ENT
null
cc224eb0-6588-4be6-9341-76c5d4f45270
True statements regarding epilepsy in pregnancy is:
Seizure frequency decreases in majority
Monotherapy is preferred to polydrug therapy
No increase in incidence of epilepsy in offspring
Breastfeeding is contraindicated
1b
multi
Ans. is b, i.e. Monotherapy is preferred to polydrug therapy --Dutta Obs 7/e, p 291As discussed earlier, seizure frequency remains unchanged in majority during pregnancy."Frequency of convulsions is unchanged in majority (50%) and is increased in some." --Dutta 7/e, p 291"The risk of developing epilepsy to the offsprin...
Gynaecology & Obstetrics
Medical & Surgical Illness Complication Pregnancy
37550fd7-46d1-4623-bb64-a1d925af5830
Spinal cord in an infant terminates at
L1
L2
L3
L4
2c
single
In premature & term neonates- it lies b/w 1st & 3rd lumbar veebrae. In children between ages of (1-7yrs)- it lies between 12th thoracic and 3rd lumbar veebra. In adults, it terminates at the level of middle 3rd of body of 1st lumbar veebra which corresponds approximately to transpyloric plane. Spinal cord occupies supe...
Anatomy
Neuroanatomy 3
76ee4517-2f17-4c9a-90bf-901f14682d41
A 67 yr male with history of chronic smoking hemoptysis with cough. Bronchoscopic biopsy from centrally located mass shows undifferentiated tumor histopathologically. Most useful I.H.C. (immunohistochemical) marker to make a proper diagnosis would be:
Cytokeratin
Parvalbumin
HMB-45
Hep-par1
0a
multi
The presence of chronic smoking, cough and hemoptysis in old man is a pointer towards a diagnosis of bronchogenic cancer. The central location suggests the possibility of a squamous cell cancer. Histologically, this tumor is characterized by the presence of keratinization and/or intercellular bridges. HMB (melanoma), H...
Pathology
Lung Tumor
5e02ac03-bcd7-4299-af6c-13c74b7826ea
Malignant cold nodule in thyroid diagnostic on USG by all EXCEPT
No cystic lesion
Irregular margins
Calcification at margin of tumour
Hypoechoic
0a
multi
(A) No cystic lesion > USG can also be used to aid in the differentiation between benign and malignant nodules. The following criteria can be used by USG, and favor a diagnosis of malignancy:1) Absence of a halo sign2) Uniformly solid tumor with occasional central necrosis3) Irregular margins4) Fine calcifications5) He...
Surgery
Miscellaneous
c4d7a407-b64a-4299-956b-43a71a09d2a5
Most common type of germinal cell tumor in testis is?
Teratoma
Embryonal carcinoma
Seminoma
Endodermal sinus tumor
2c
single
Ans. is 'c' i.e., Seminoma * Testicular tumors are divided into two major categories : (i) Germ cell tumors, and (ii) Sex cord tumors.A) Germ cell tumors# More than 95% of testicular tumors are germ cell tumors. They are further divided into -i) Seminoma* It is the most common germ cell tumor of testis. Female counterp...
Pathology
Male Genital Tract
2fe9b9ab-7973-472b-a08d-af1afa5608a8
An order for exhumation can be given by: Maharashtra 08
District collector
Additional district magistrate
Sub-collector
Any of the above
3d
multi
Ans. Any of the above
Forensic Medicine
null
d0b80584-9ab0-477e-a844-187560c2d54b
Langerhans cells in skin are :
Antigen presenting cells
Pigment producing cells
Keratin synthesisng cells
Sensory neurons
0a
single
A i.e Antigen presenting cells
Skin
null
a18d43d0-c54e-44eb-a80a-346c206ebbcf
In hyperkalemia with bradycardia treatment is: -
Calcium gluconate
Steroid
Salbutamol
K+ resin
0a
single
The treatment for hyperkalemia can be thought of in 3 distinct steps. First, antagonize the effects of hyperkalemia at the cellular level (membrane stabilization). Second, decrease serum potassium levels by promoting the influx of potassium into cells throughout the body.(insulin,beta2 agonist) Third, remove potassium ...
Medicine
ECG and Arrhythmias 1
0f1909b4-9e8a-4be9-9b38-f9bd0aa22dfe
In human body, methionine is synthesized from ?
Cysteine
Proline
Threonine
None
3d
multi
Ans. is 'd' i.e., None Methionine is an essential amino acid, cannot be synthesized in body.
Biochemistry
null
d679cbbc-5167-4004-b2ce-e2f6f29dc960
Not a common cause of night blindness:
Cataract
RP
Oguchi disease
Pathological myopia
0a
single
Cataract is not a common cause of night blindness. Other causes are more recognized causes. Causes of Night Blindness Vitamin A deficiency (first symptom is red-green differentiation anomaly) Pathological myopia Tapetoretinal degenerations{eg. Retinitis pigmentosa(RP)} Familial congenital night blindness Oguchi's disea...
Ophthalmology
Neuro Ophthalmology
291d5c67-079f-4fc0-98c0-e35c3f1cf723
In recent surveillance reports cases of diphtheria are reducing. This is due to -
Chemoprophylaxis
Improved standard of living
Vaccination
Health education
2c
single
Ans. is 'c' i.e., Vaccination o The reduced incidence of diphtheria in India is primarily due to the high coverage of appropriate immunization in children and to an apparent reduction in toxin-producing strains of the bacterium.
Social & Preventive Medicine
Diphtheria
d411bf42-cc87-43c8-b545-4867293a74d3
Total lung capacity depends on:
Size of airway
Closing tidal volume
Lung compliance
Residual volume
2c
single
Ans. C. Lung compliancea. TLC is the maximum volume to which the lungs can be expanded with the greatest possible inspiratory effort.b. TLC=IRV+TV+ERV+RV=IC+RVc. Compliance (stretch ability) of lungs: D is increased in Emphysema (obstructive lungs dis) and decreased in Interstitial pulmonary fibrosis (Restrictive lung ...
Physiology
Respiratory System
f0ec4b5a-e631-40fb-9c51-14f9d877d6f4
Which of the following decrease sex hormone binding globulin
Oral contraceptive pills
Insulin
Thyroxine Hormone
Pregnancy
1b
single
null
Gynaecology & Obstetrics
null
a95598c5-7baa-4c35-a3bd-2027974759f9
A 65-year-old man suffers a sudden fall in mean aerial pressure, 4 hours after his CABG surgery. Other findings include elevated JVP. What is the best next step in the management of this case?
PRBC Transfusion
Vasopressors along with the inotropes
Immediate re-exploration of the mediastinum
Intra-aoic balloon pump
2c
multi
This clinical presentation points towards a likely diagnosis of Cardiac tamponade. It is a common complication post CABG. It can be confirmed on an Echocardiography. It is a life-threatening condition hence it should be managed by immediate return to the OT for exploration and drainage of mediastinal hematoma.
Surgery
Thorax And Mediastinum
eeb66d6f-fb93-4291-8af6-b0671388b458
Type IV complex of ETC is inhibited by
Oligomycin
Antimycin
Cyanide
CO2
2c
single
Cyanide is probably the most potent inhibitor of ETC (Complex IV). It binds to Fe3+ of cytochrome oxidase blocking mitochondrial respiration leading to cell death. Cyanide poisoning causes death due to tissue asphyxia (mostly of the central nervous system) In Acute cyanide poisoning Amyl nitrite is given followed by so...
Biochemistry
FMGE 2019
7ef8dfdf-60ce-4701-8fd5-f7a6553d8fb9
A 60 yr old smoker came with a history of painless gross hematuria for one day. Most logical investigation would be
Urine routine
Plain X ray KUB
USG KUB
Urine microscopy for malignant cytology
3d
single
In this case, we should suspect bladder carcinoma ( transitional cell carcinoma ) . Smokers are at a higher risk of developing TCC.Other risk factors being chemical .industry workers in western countries and schistosomiasis in endemic regions . It is more common in males -3:1. They usually presents with painless gross ...
Surgery
Urology
b7dd95d8-e3a4-4562-aa6d-cea8f6f9daac
Which Ca has best prognosis:
Carcinoma lip
Carcinoma cheek
Carcinoma tongue
Carcinoma palate
0a
single
Oral malignancy with best prognosis is carcinoma lips. Oral cancer with worst prognosis is floor of mouth carcinoma.
ENT
null
4ef8a385-8685-4e05-82ba-f852da1c95ca
Net reproduction rate is :
Number of girl babies born to a women
Number of babies born to a women
Number of girl babies born to a women and taking into account only alive once
None of the above
2c
multi
Total Fertility Rate(TFR) : Number of babies born to a woman Gross Fertility Rate(GFR) : Number of girl babies born to a woman Net reproduction rate(NRR) : Number of girl babies born to a woman and taking into account only alive once.
Social & Preventive Medicine
null
301e8f91-f5fc-4073-94a7-b9e6abf97d72
What is the common change in cell death associated with both apoptosis and necrosis ?
Cell shrinkage
Bleb formation
Chromatin condensation
Presence of inflammation
2c
multi
Answer- C. Chromatin condensationBoth form of cell death, finally lead to nuclear changes i.e. chromatin condensation (pyknosis).
Pathology
null
8a4b25d1-a225-465a-9845-b866b911232b
Drug the choice for hyperthyroidism in first trimester of pregnancy is
Methimazole
Propylthiouraril
Carbimazole
Perchlorate
1b
single
Propylthiouracil is the only thioamide which is least teratogenic and hence it is the drug of choice to hyperthyroidism in pregnancy and lactation.
Pharmacology
null
36059aab-677f-4156-8ff8-0ba0327b51bf
Which of the following coagulation factors causes cross-linking and stabilization of clot?
Factor XIII
Thrombin
Factor VIII
Factor IX
0a
single
The loose aggregation of platelets in the temporary plug is bound together and conveed into definitive clot bg fibrin. Fibrin is initially a loose mesh of interlacing strands. It is conveed by the formation of covalent cross-linkages to a dense tight aggregate. The latter reaction is catalyzed by activated factor 13 an...
Physiology
Cardiovascular system
4f51b5ae-b096-4799-aa67-cca487e45df8
Phage typing is widely used for the intraspecies classification of one of the following bacteria -
Staphylococci
E. coli
Klebsiella pneumoniae
Pseudomonas aeruginosa
0a
single
null
Microbiology
null
0ba8f749-55e4-4ff3-bd9a-dcaea7af1835
The first step when doing a pneumonectomy for cancer of the bronchus is to:
Ligate the pulmonary vein
Ligate pulmonary aery
Divide the bronchus
Perform lymph node clearance
1b
multi
Pneumonectomy Pneumonectomy is anatomically more straightforward than lobectomy (in carcinoma bronchus): The pulmonary aery is first dissected, divided and sutured. The pulmonary veins are then isolated divided and sutured. The main bronchus is divided so that no blind stump remains. The technique of stump closure is i...
Surgery
Thorax And Mediastinum
366600fe-eb40-4d9a-bd9f-d9c8f0082dcd
All are true about DOTS, except ?
Sho course of chemotherapy
Drugs are given free of cost
Supervised drugs intake in intensive phase
Daily treatment is recommended
3d
multi
Ans. is 'd' i.e., Daily treatment is recommended Directly observed treatment sho course (DOTS) In the Revised National Tuberculosis Control Programme (RNTCP), patients are provided sho course chemotherapy as DOTS. All patients are provided sho-course chemotherapy free of charge. During the intensive phase of treatment ...
Social & Preventive Medicine
null
c7f9fab1-4168-46a1-9291-705eb0cd0c43
A patient on warfarin was given phenobarbitone, The result would have been -
Increase the dose of warfarin
Decrease the dose of warfarin
Increase the dose of phenobarbitone
Decerease the dose of phenobarbitone
0a
single
Ans. is 'a' i.e., Increase the dose of warfarin
Pharmacology
null
88bd8dd0-5572-4109-8ab9-241a5e04085d
Which of the following dings is not used for anxiety?
Propanolol
Aiprazolam
Buspirone
Haloperidol
3d
single
Ans. is 'd' i.e., Haloperidol
Pharmacology
null
a0898369-2a07-4dee-b43c-6db914fc7175
True about carotid body receptors ?
Most potent stimulus is high PCO2
Dopamine is neurotransmitter
Low blood flow
Afferent through vagus nerve
1b
multi
Ans. is 'b' i.e., Dopamine is neurotransmitter Peripheral chemoreceptors The peripheral chemoreceptors which regulate respiration are located in the carotid body and aoic bodies. These bodies are located in the connective tissue associated with the vessel wall, at the bifurcation of the common carotid, and on the arch ...
Physiology
null
32f92251-058a-4101-86e4-69e0e3929edf
A mother calls you on the telephone and says that her 4-year-old son bit the hand of her 2-year-old son 2 days ago. The area around the injury has become red, indurated, and tender, and he has a temperature of 39.4degC (103degF). Which of the following is the most appropriate response?
Arrange for a plastic surgery consultation at the next available appointment.
Admit the child to the hospital immediately for surgical debridement and antibiotic treatment.
Prescribe penicillin over the telephone and have the mother apply warm soaks for 15 minutes four times a day.
Suggest purchase of bacitracin ointment to apply to the lesion three times a day.
1b
multi
Human bites can pose a significant problem. They can become infected with oropharyngeal bacteria, including S aureus, Streptococcus viridans, Eikenella corrodens, and anaerobes. A patient with an infected human bite of the hand requires hospitalization for appropriate drainage procedures, Gram stain and culture of the ...
Pediatrics
Growth, Development, and Behavior
7bf2b381-3b5d-408a-8b8d-91843953adee
Most common malignancy in children is –
Leukemia
Lymphoma
Wilm's tumor
Neuroblastoma
0a
single
Most common childhood tumor → Leukaemia Most common childhood leukemia → ALL Most common solid tumor of childhood → Brain tumor Most common tumor in infancy → Neuroblastoma Most common abdominal tumor in child → Neuroblastoma
Pediatrics
null
da6c0cfc-0bc2-4ccd-b640-124cb4bc2bee
A factory worker presents with excessive salivation, blue lines on gums, tremors, disturbed personality, insomnia, and loss of appetite. The most likely poisoning is -
Mercury
Lead
Arsenic
Phosphorus
0a
single
Excessive salivation, blue line on gums, tremors (i.e. Hatter's shake), disturbed personality (i.e. erethism) and loss of appetite (anorexia) suggest the diagnosis of mercury poisoning.
Forensic Medicine
null
af573629-e465-47a1-9544-c520a4c44597
Role of carnitine in lipid metabolism -
Catalyzation of the cyclization sequence
Essential for extracellular transfer of fatty acids
Essential for biosynthesis of fatty acids
Transfer of activated long chain FFA into mitochondria
3d
single
Ans. is 'd' i.e.. Transfer of activated long chain FFA into mitochondria o Activated long chain fatty acid (acyl CoA) cannot penetrate inner mitochondrial membrane.o Acyl group of acyl CoA is transferred to carnitine, resulting in formation of acylcarnitine.o Acylcarnitine is then transported across the inner mitochond...
Biochemistry
Lipid Oxidation and Synthesis
1a1c1412-b518-4dfe-859f-f2c7c82278e5
CAMP reaction is shown by which streptococci?
Group A
Group B
Group C
Group D
1b
single
Ans. b (Group B). (Ref. Textbook of microbiology by Ananthanarayan 6th ed. 187).Serological or Lancefield classification system for streptococci1Group A streptococciCatalase -,Beta-hemolysis,Bacitracin sensitive,PYR test +,Ribose not fermented.Includes Streptococcus pyogenes.2Group B streptococciCAMP + and Beta-hemolys...
Microbiology
Bacteria
33c55ea6-00ad-44e9-9af8-5d7ac4d03646
One gram of smokeless gunpowder produces: Karnataka 11
3000-4000 cc of gas
9000-10,000 cc of gas
12,000-13,000 cc of gas
15,000-16,000 cc of gas
2c
single
Ans. 12,000-13,000 cc of gas
Forensic Medicine
null
9b424535-eb42-4c23-a467-7a50cf60c294
Cranial pa of accessory nerve supplies
Sternocleidomastoid
Trapezius
Levator scapulae
Levator palatini
0a
single
Sternocleidomastoid and trapezius develop from branchial arch mesoderm and are supplied by spinal pa of the accessory nerve. Levator scapulae are supplied by a branch from dorsal scapular nerve and branches from C3, C4. BD Chaurasia 7th edition Page no: 65
Anatomy
Upper limb
79103c19-09f0-4e51-865e-ce76f2219d88
Marcus Gunn pupil is due to -
Total afferent pupillary defect
Relative afferent pupillary defect
Efferent pathway defect
Cerebral lesion
1b
single
The Relative Afferent Pupillary Defect (RAPD), or Marcus-Gunn Pupil is an extremely significant and highly objective clinical finding in the examination of the visual system. The "swinging flashlight test" is probably the best test for identifying an RAPD. In this test, a strong, steady light is used. The light is shin...
Ophthalmology
Neuro-ophthalmology
04f88cb5-f9f0-4906-b45d-b223bc90ede1
The impression with the least dimensional change upon disinfection is
Addition poly silicone
Agar-agar
Polysulphide
Polyether
0a
single
null
Dental
null