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135
9399121c-1b6d-4df0-9538-77c0bfb0c301
Initial amino acid in prokaryotic protein synthesis ?
Arginine
Methionine
Formyl-methionine
Alanine
2c
single
Ans. is 'c' i.e., Formyl-methionine
Biochemistry
null
c502b189-722a-411f-8beb-0f0a4faa9896
"Tear drop" sign on X-ray PNS is seen in
Blow out fracture of the floor of the orbit
Comminuted fracture of the maxilla
Fracture of the nasal bone
Fracture of the mandible
0a
single
Ans. a (Blow out fracture of the floor of the orbit) (Ref. Grainger Diagnostic Rad 4th/2527; Ref . Q. 159. Of MH-2207)BLOW-OUT FRACTURE is caused by fracturing of the orbital walls with herniation of orbital contents and subsequent tethering of the globe, resulting in pain and diplopia. It usually involves the orbital ...
ENT
Nose and PNS
204d5328-da8f-4ae6-8e91-7b4cafa01289
Which classification is used to divide the liver into segments?
Couinaud
Muhe
Starzl
Anatomical
0a
single
Ans. (a) Couinaud'sRef: Bailey and Love 26th edition page 1066* Couinaud divided the liver into multiple segments- 8 segments* He is a French Anatomist
Surgery
Liver
8980a262-df85-4c2a-a508-c8975cb3dcdf
In a patient with compensated liver cirrhosis presented with history of variceal bleed. The treatment of choice in this patient is -
Propranolol
Liver transplantation
TIPS (Transjugular intrahepatic poal shunt)
Endoscopic sclerotherapy
3d
single
When a cirrhotic patient presents with upper GI bleed, the single most impoant diagnostic as well as therapeutic procedure to be performed is endoscopy (although after intravenous fluid resuscitation and correction of coagulation abnormalities) If varices are found they are treated by either Endoscopic variceal ligatio...
Anatomy
G.I.T
c630a539-d29a-4e01-9a3f-19af15384684
During an emergency thoracotomy, the incision is made > 1cm lateral to the sternal margin. This will preserve which of the following structures?
Intercostal aery
Superficial epigastric aery
Internal mammary aery
Intercostal vein
2c
single
In case of anterolateral thoracotomy, which is usually a transverse or a veical incision staing from fouh intercostal space, incision is made lateral to sternal in order to avoid injury to the adjacent vessels which include internal mammary aery. Superficial epigastric aery is the terminal branch of internal mammary ae...
Surgery
null
c21b2211-2b4f-4cc3-a3c6-31817a867e4f
Causative organism of rheumatic fever -
Group A Streptococci
Staphylococci
Group B Streptococci
Group D Streptococci
0a
single
Ans. is 'a' i.e., Group A Streptococci Rheumatic fevero Rheumatic fever (RF) is an acute, inununologically mediated, multisystem inflammatory disease classically occurring a few weeks after an episode of group A streptococcal pharyngitis; occasionally, RF can follow streptococcal infections at other sites, such as the ...
Pathology
Rheumatic Fever
bda4eeca-8d5a-418c-90ba-9a3c90fc01ba
Kliiver-Bucy syndrome is associated with lesion in the following area of brain
Amygdala
Cerebral cortex
Hippocampus
Mammillary body
0a
single
(A) Amygdala # Kliiver-Bucy syndrome is a behavioral disorder that occurs when both the right and left medial temporal lobes of the brain malfunction. People with lesions in their temporal lobes show similar behaviors.> They may display oral or tactile exploratory behavior (socially inappropriate licking or touching); ...
Medicine
Miscellaneous
c3653ee1-d4b3-4bd3-962b-fe81aeab98b9
Surest sign of brain stem death
Absent Doll's eye reflex
Fixed dilated pupil not reacting to light
Cheyne Stokes breathing
Decerebrate posture
1b
single
B i.e. Fixed dilated pupil not responding to light Cooling of body & rigor mois is a sign of molecular or cellular death. - Somatic (systemic, clinical or brain) death is cessation of spontaneous breathing, circulation and brain activity (as indicated by flat isoelectric EEG, deep unconsciousness with no response to ex...
Forensic Medicine
null
af90d178-d794-4bfa-b083-fb3fd86e900b
Stereoanesthesia is due to lesion ofa) Nucleus Gracilisb) Nucleus cuneatusc) Cerebral cortexd) Spinothalamic tract
abc
bc
acd
bcd
0a
single
Astereognosis/Stereoanaesthesia- Loss of ability to recognize size and shape of an object. Seen in- lesion of somatosensory cortex, lesion of tractus cuneatus, lesion of tractus gracilis. Somatosensory cortex lesion- proprioception and tactile sensations are lost while pain and temperature sensations are preserved. Tr...
Physiology
null
f8ce8f8d-88a7-4003-9cb0-08f86e620ccc
A 70-years old male presented with asymptomatic white patch on oral cavity following application of the denture. Treatment of choice is
Low does radiotherapy
Biopsy of the all the tissues
Asceaining that denture is fitted properly
Antibiotics
2c
multi
Leukoplakia regress spontaneously after stopping alcohol or tobacco consumption or correction of underlying cause
Anatomy
All India exam
ca7c9a11-c130-4b26-a754-d55e4f9a6b16
Radiological hallmark of primary tuberculosis in childhood is-
Ghon's focus
Normal chest Xray
Lymphadenopathy
Pleural effusion
2c
multi
Ans. is 'c' i.e., Lymph adenopathy Primary tuberculosis in childhoodo Primary' tuberculosis in childhood can present in 4 major ways in addition to the normal chest radiography. These are:LymphadenopathyLobar or segmental parenchymal diseasePleural effusionMilitary involvemento Lymphadenopathy with or without parenchym...
Radiology
Imaging of Alveolar Lung Disease
37995a81-8832-4afc-bd52-48359786c5e7
Positive shick's test indicates that person is ?
Immune to diptheria
Hypersensitive to diptheria
Susceptible to diptheria
Carrier of diptheria
2c
single
Ans. is 'c' i.e., Susceptible to diphtheria Shick test . Shick test is no longer in use. It was used for the susceptibility of for diphtheria. . It was an intradermal test, in which after intradermal injections of diphtheria toxin in one forearm (usually left) and toxoid in other forearm two readings were taken one at ...
Microbiology
null
dd55dfdf-bd63-4eb6-a39c-8480fc69cbb2
Dependency' ratio includes -
Less than 15 years
Less than85 years
30-50 years
None
0a
multi
Ans. is 'a' i.e.. Less than 15 years Dependency ratiooThe proportion of persons above 65 years of age and children below 15 years of age are considered to be dependent on the economically productive age group {15-64 years).o The ratio of combined age group 0-14 years plus 65 years and above to the 15-65 years age group...
Social & Preventive Medicine
Demography
3baba3af-86c3-4a17-a72f-315e4d88ba99
All the following are indications for termination of pregnancy in APH patient except:
37 weeks
IUD
Transverse lie
Continuous bleeding
2c
multi
Ans. is c, i.e. Transverse lieRef. Dutta Obs. 7/e, p 249In these questions, there is no confusion about any option except for 'lie of the fetus'.As far as lie is concerned:Friends, why would you terminate pregnancy just because of unstable lie or transverse lie, unless and until there is some other complication associa...
Gynaecology & Obstetrics
Antepartum Haemorrhage
a0bd58d7-b1af-4e90-95fc-03e2f2b1d99d
An eight-month-old female infant presented with recurrent episodes of hypoglycemia, especially if time interval of feeding is increased. Dicarboxylic acid is present in the urine. Urine ketone bodies is negative. The child responded well to IV Glucose, less fat and more carbohydrate diet, frequent feeding. The child wa...
Increased dicarboxylic acid inhibit glycogenolysis
Lack of ATP to support gluconeogenesis
Lack of acetyl-CoA to favour glycogenolysis
Glycogen stores are inadequate in infants
1b
multi
Ans. B. Lack of ATP to support gluconeogenesis* This is a case of MCAD deficiency.* Identifying features are:* Recurrent episodes of hypoglycaemia is time interval of feeding increased* Dicarboxylic acids in urine* Absence of ketone bodies in urine* Reasons for hypoglycemia are:* Due to MCAD deficiency, beta oxidation ...
Biochemistry
Carbohydrates
eac94128-0363-4e60-a93a-80f2a4cd952b
Hypersensitivity vasculitis usually involve
Aerioles
Post capillary venules
Capillaries
Medium sized aeries
1b
multi
Refer robbins 9/e p510, 8/e 515 Harrison 7/2128 Direct quote from Harrison 18th /2798; Postcapillary venules are most commonly involved vessels. Capillaries and aerioles are less frequent involved
Anatomy
Cardiovascular system
5b7e48f0-5c0e-41aa-8dc3-325244f33bae
Amino acid absorption is by:
Facilitated transport
Passive transport
Active transport
Pinocytosis
2c
single
Ans. C. Active TransportFree amino acids are absorbed across the intestinal mucosa by sodium-dependent active transport. There are several different amino acid transporters, with specificity for the nature of the amino acid side-chain.Transporters of Amino AcidsFor Neutral Amino acidsFor Basic Amino acids and Cysteine....
Biochemistry
Proteins and Amino Acids
cf2b651f-066f-4354-836f-1b5e10eb6f46
Hyponatremia in multiple myeloma is -
TRUE
Relative
Absolute
Pseudo
3d
multi
• Patients with multiple myeloma also have a decreased anion gap because the M component is cationic, resulting in retention of chloride. • This is often accompanied by hyponatremia that is felt to be artificial (Pseudohyponatremia) because each volume of serum has less water as a result of the increased protein.
Surgery
null
be937085-bdc9-4487-aea6-4b5b2aa4cd96
Index case is the -
First case in a community
Case getting infection from primary case
Case getting infection from secondary case
First case detected by investigator
3d
single
Ans. is 'd' i.e., First case defected by investigator [Ref: Park 22nd/e d. 92 & 21st/e p. 9/1o Primary caseo Index case--First case of communicable disease introduced into the population.First case to come to attention of the investigator.o It is not always necessary that primary case will be index case : -When the fir...
Social & Preventive Medicine
Infectious Disease Epidemiology
653e1924-a0e6-4c37-8671-d25d8832c02e
Gastrojejernostomy surgery belongs to
Clean surgery
Contaminated surgery
Clean contaminated surgery
Dirty surgery
2c
single
Clean contaminated surgery : Wound is exposed to not only skin but also GI tract / Respiratory tract / Urinary tract organism in controlled enviroment. Hence Gastrojejunostomy surjery belongs to this category.
Surgery
null
ea9560ec-7791-4d43-8f27-b1389e1e9e16
Hand and foot syndrome is due to ?
Vincristine
Cisplatin
5 FU
Azathioprine
2c
single
Ans. is 'c' i.e., 5 FU
Pharmacology
null
00d1d295-5998-4780-b5c8-3541ce055bd0
Gaisbock syndrome is better known as?
Primary familial polycythemia
High-altitude erythrocytosis
Spurious polycythemia
Polycythemia vera
2c
single
Gaisbock syndrome is characterised by secondary polycythemia. It occurs mainly in male sedentary individuals, on a high-calorie diet. Prevalence is unknown. The clinical picture includes mild obesity, hypeension and decrease in plasma volume with relative increase in hematocrit, blood viscosity, serum cholesterol, trig...
Medicine
Haematology
48d2615c-1348-4130-a284-488b5b5ce8f8
After an incised wound, new collagen fibrils are seen along with a thick layer of growing epithelium. The approximate age of the wound is -
12-24 hours
24-72 hours
4-5 days
About 1 week
2c
single
. 4-5 days
Pathology
null
7acb1377-ee33-4ba0-96af-d6389e13e975
Thyrotoxic periodic paralysis leads to extreme muscle weakness due to?
Hypokalemia
Hypocalcemia
Hypomagnesemia
Hyponatremia
0a
single
T3| T4| - Positive Na- K+ ATPase activity in the cells (3 Na outside 2 K+ inside) | K Influx | K| | Thyrotoxic Periodic Paralysis
Medicine
Diseases of Thyroid
44fd2133-14eb-4365-845e-3b7739786c2f
vitamin involved in 1 carbon metabolism
Folic acid
Thiamine
biotin
niacin
0a
single
THFA is the carrier of One Carbon groups The folic acid is first reduced to 7,8-dihydrofolic acid and fuher reduced to 5,6,7,8-tetrahydrofolic acid (THFA) . Both reactions are catalyzed by NADPH dependent folate reductase. The THFA is the carrier of one-carbon groups. One carbon compound is an organic molecule that con...
Biochemistry
vitamins
5719db2c-6692-4a88-8f7c-2bd05263ecba
Cauliflower ear is -
Keloid
Perchondritis in Boxers
Squamous cell carcinoma
Anaplastic cell carcinoma
1b
single
null
ENT
null
58d4ffc2-c6bf-4c39-a61d-42edcdfbad08
Which of the following diuretics is contraindicated in the presence of cardiac failure?
Mannitol
Spironolactone
Furosemide
Hydrochlorothiazide
0a
single
null
Pharmacology
null
c58ae922-9ef2-42b4-96f7-4bf55d921817
Snow blindness is caused by :
Ultravoilet rays
Infrarads
Microwaves
Defect in mirror
0a
single
A i.e. Ultra violet rays
Ophthalmology
null
544ffd62-236b-4893-9a4d-7279e93ab84c
The most common neoplasm among HIV positive homosexual males:
Non-Hodgkin's lymphoma
Glomus tumor
Kaposi's sarcoma
None of the above
2c
multi
null
Medicine
null
45e6c5a2-1420-48d3-b5fb-87667ce15e08
Hyponatremia in multiple myeloma is
TRUE
Relative
Absolute
Pseudo
3d
multi
Pseudohyponatremia Patients with multiple myeloma also have a decreased anion gap because of the M component is cationic, resulting in retention of chloride This is often accompanied by hyponatremia that is felt to be aificial (pseudohyponatremia) because each volume of serum has less water as a result of the increased...
Surgery
General surgery
697b6579-7c0e-4b03-a149-96b25aa0d146
Schiller-Duval bodies are seen in-
Teratoma
Seminoma
Yolk sac tumour
Chorio Carcinoma
2c
single
Yolk sac tumor of the testis: Raised a-fetoprotein level (AFP). Schiller-Duval bodies. Schiller-Duval body: It is the characteristic feature of the endodermal sinus tumor. This is a glomerulus-like structure composed of a central blood vessel enveloped by germ cells within a space lined by germ cells. Endodermal sinus ...
Pathology
Urinary tract
01dab660-369d-42be-9871-53164591f758
Which one of the following disorders is related to sense of unreality?
Depersonalization disorder
Derealization disorder
Delusion
Phobias
0a
single
Ans. A. Depersonalization disorderDepersonalization:Depersonalization is a sense of unreality or strangeness concerning the self, manifested by feeling detached from and being an outside observer of one's mental processes or body.A patient who experiences depersonalization may describe feeling like things "I have stepp...
Psychiatry
null
027b9811-e511-4d01-8c93-2099f4e39f7f
Floaters can be seen in following except
Vitreous haemorrhage
Retinal detachment
Uveitis
Acute congestive Glaucoma
3d
multi
Black spots or floaters in front of the eyes may appear singly or in clusters. They move with the movement of the eyes and become more apparent when viewed against a clear surface e.g., the sky. Common causes of black floaters are:  Vitreous hemorrhage Vitreous degeneration e.g., - senile vitreous degeneration, vitreo...
Ophthalmology
Anatomy, Development and clinical examination
0a5e5d05-5d36-4eca-a464-cec53a160ea0
Term psychoanalysis was coined by?
Eysenck
Freud
Jung
Adler
1b
single
Ans. is 'b' i.e., Freud * The credit for invention of psychoanalysis belong to Sigmund FreudImportant contributors in psychiatryTermCoined by* Demence precoce* Moral Emil* Dementia precox* Kraepelin* Catatonia, cyclotymia* Kahlbaum* Hebephrenia* Hecker* Schizophrenia* Eugen Bleuler* Ambivalence* Eugen Bleuler* Free ass...
Psychiatry
Psychoanalysis
19de9e2f-472f-40ab-8530-767da4bb3910
CSOM with Picket fence fever is seen in
Meningitis
Sigmoid Sinus Thrombosis
Brain Abscess
Extradural Abscess
1b
single
Sigmoid sinus thrombosis/lateral sinus thrombosis is an inflammation of inner wall of lateral venous sinus with formation of an intra sinus thrombus It occurs as a complication of chronic suppuration of middle ear or acute coalescent mastoiditis, and cholesteatoma Picket fence fever temperature never comes back to norm...
ENT
Complications of Chronic Otitis Media
77ded5ec-a12d-469a-a16f-fd7871c27c98
Which dietary deficiency of a vitamin can cause Pellagra.
Vitamin C
Niacin
Vitamin D
Biotin
1b
single
Some amino acids (isoleucine, tryptophan, phenylalanine, and tyrosine) are both glucogenic and ketogenic because their degradation pathway forms multiple products.a. Amino acids that are converted to pyruvate (see Figure I).(1). The amino acids that are synthesized from the intermediates of glycolysis (serine, glycine,...
Biochemistry
Vitamins and Minerals
1d939c71-c8f5-42a8-94a1-62b3f85c2445
Good prognostic factor for schizophrenia is ?
Blunted affect
Early onset
Presence of depression
Male sex
2c
single
Ans. is 'c' i.e., Presence of depression Good prognostic factors :- Acute onset; late onset (onset after 35 years of age); Presence of precipitating stressor; Good premorbid adjustment; catatonic (best prognosis) & Paranoid (2nd best); sho duration (< 6 months); Married; Positive symptoms; Presence of depression; famil...
Psychiatry
null
ce01e569-bf1c-40c5-bc57-bda928225325
All drug inhibit bacterial cell wall synthesis EXCEPT
Spectinomycin
Vancomycin
Aztreonam
Cephalexin
0a
multi
Spectinomycin is an aminocyclitol antibiotic that inhibits bacterial protein synthesis. The other drugs all inhibit bacterial cell wall synthesis. Vancomycin and bacitracin inhibit early steps in the biosynthesis of the peptidoglycan component of the cell wall, whereas 3-- lactams such as aztreonam (a monobactam), peni...
Pharmacology
null
a07737a9-2d74-4807-9182-aef521be32c1
The most common cause of death in Kaposi's Sarcoma is -
Dissemination
AIDS
Massive pulmonary haemorrhage
Diabetes mellitus
2c
single
null
Medicine
null
87ac2153-96e5-4df6-ba4d-389eaab02de1
Longest and thinnest extrocular muscle -
SR
IR
SO
IO
2c
single
SO arises from the bone above and medial to the optic foramina. It runs forward and turns around a pulley- " the trochlea" and is inseed in the upper and outer pa of the sclera behind the equator. Ref;A.K.Khurana; 6th edition;Page no:336
Ophthalmology
Ocular motility and squint
863563ce-3fce-491b-92f6-3bc13d8a2d16
Ribosomes has following enzymatic activity?
Peptidyl transferase
Peptidase
Aminoacyl tRNA synthetase
GTPase
0a
single
The formation of peptide bonds is catalysed by peptidyl transferase, an activity intrinsic to the 23 S r-RNA of 50 S subunit in prokaryotes and 28 S r-RNA of 60 S subunit in eukaryotes. So, it is referred to as ribozyme & indicates a direct role of r-RNA in protein synthesis.
Biochemistry
null
eb09e278-8f3b-4e17-b853-54b536926b06
Inhibin inhibits the secretion of which hormone :
FSH
LH
Estrogen
Prolactin
0a
single
FSH
Gynaecology & Obstetrics
null
7324c16c-ec99-482b-9d83-16d5a8f9d6a8
True regarding traumatic facial nerve palsy is all, except
Usually occurs with transverse petrous temporal bone fracture
Usually occurs with longitudinal petrous temporal bone fracture
Posttraumatic facial nerve palsy may be complete at the time of presentation
Decompression of the canal can be useful treatment
1b
multi
TRAUMA TIC FACIAL NERVE PARALYSIS 1. FRACTURES OF TEMPORAL BONE Fractures of temporal bone may be longitudinal, transverse or mixed. Facial palsy is seen more often in transverse fractures (50%). Paralysis is due to intraneural haematoma, compression by a bony spicule or transection of nerve. In these cases, it is impo...
ENT
All India exam
eef0905b-965f-4a6b-bd06-604bded9c566
Mean Hb values in two population groups are compared by
Paired t test
Unpaired t test
Chi square test
Fischer test
1b
single
Ref:Park's Textbook of Preventive and Social Medicine 25th Ed
Social & Preventive Medicine
Biostatistics
44951bf6-36b2-4283-b511-3075505c9e1b
A chest physician performs bronchoscopy in the procedure room of the out patient depament. To make the instrument safe for use in the next patient waiting outside, the most appropriate method to disinfect the endoscope is by -
70 % alcohol for 5 min
2% glutaraldehyde for 20 min
2% formaldehyde for 10 min
1% sodium hypochlorite for 15 min
1b
single
Glutaraldehyde is especially effective against the tubercle bacilli, fungi, and viruses. It is less toxic and irritant to eyes and skin than formaldehyde. It has no deleterious effects on the cement or lenses of instruments such as cystoscope and bronchoscopy It can be safely used to treat corrugated rubber,nanesthetic...
Microbiology
general microbiology
47f7e154-421c-4628-bc72-a8edf7c3c33c
Most important amino acid for formation Neutrophilic extracellular trap (NET) is
Leucine
Methionine
Citrulline
Valine
2c
single
Conversion of arginine residues to Citrulline in the histones is an essential step in the formation of neutrophill extracillular traps.
Pathology
null
b73f47f6-3b20-49ac-9207-544e3d53220d
All muscles of the pharynx are supplied by pharyngeal plexus, EXCEPT?
Inferior constrictors
Salpingopharyngeus
Stylopharyngeus
None of the above
2c
multi
With the exception of stylopharyngeus, which is supplied by the glossopharyngeal nerve, the muscles are supplied by the cranial pa of the accessory nerve the pharyngeal plexus.
Anatomy
null
039be0b0-ecb7-47f0-be51-4e1ad708834e
On exertion urine stream increases in -
Prostate enlargement
Marion's disease
Post. urethral valves
Urethral stricture
3d
single
null
Surgery
null
88224960-32ab-424f-8817-82cb0d84b1fd
Mauriac's syndrome is characterized by all except
Diabetes
Obesity
Dwarfism
Cardiomegaly
3d
multi
Ans. is 'd' i.e., Cardiomegaly Mauriac Sydrome Children with poorly controlled type I diabetes may develop Mauriac syndrome. It is characterized by : - Growth attenuation Delayed pubey Hepatomegaly Abnormal glycogen storage and steatosis Cushingoid features Rare in modern era of insuling therapy but is occasionlly repo...
Medicine
null
de228ccd-31cc-4308-aca2-6ff9b861bf41
Which is not transmitted by arthropod -
Rickettsia prowazekii
Coxiella burnetii
Rickettsia akari
Rickettsia rickettsii
1b
single
null
Microbiology
null
a08060f3-90a6-4a9e-a269-342a067a11ce
All of the following are true about Herpes group virus except-
Ether sensitive
May cause malignancy
HSV II involves below diaphragm
Burkitt's lymphoma involves Tcells
3d
multi
Herpes viruses are susceptible to fat solvents like alcohilic ether chlorofirm and bike salts. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO:466
Microbiology
Virology
86275511-77fc-43c3-a868-423d1cde049a
The diabetes control and complication trial (DCCT) provided definitive proof that reduction In chronic hyperglycemia helps to improve -
Microvascular complications of type 1 DM
Microvascular complications of type 1 DM
Microvascular complications of type 2 DM
Macro vascular complications of type 2 DM
0a
single
The Diabetes Control and Complications Trial (DCCT) found definitive proof that a reduction in chronic hyperglycemia can prevent many of the complications of type 1 diabetes mellitus (DM). This multicenter randomized trial enrolled over 1400 patients with type 1 DM to either intensive or conventional diabetes managemen...
Medicine
Endocrinology
991e3b31-33bd-48f7-8ce3-29243c256121
. True about polio is all except:
Sabin vaccine is attenuated, oral vaccine
Salk is a killed formalized vaccine used
Vaccine induced polio is usually due to Type 2 virus
Most common type of virus in epidemics is Type 1
2c
multi
Vaccine induced polio" is usually due to Type 2 virus
Social & Preventive Medicine
null
a413bd92-c958-482a-a848-aec3d592f395
Strawberry gingivitis is seen in:
Wegener's Granulomatosis
Scorbutic Gingivitis
Plasma Cell Gingivitis
Leukemic Gingivitis
0a
single
null
Pathology
null
4a02e1aa-2942-4fe9-87b5-cda43f5c2684
Bleomycin toxicity is characterized by destruction of:
Endothelial cells
Type I pneumocytes
Type II pneumocytes
Alveolar macrophages
1b
single
Ans. b. Type I pneumocytes Bleomycin toxicity is characterized by destruction of Type I pneumocytes.Histopathotogy of Lung in Bleomycin Toxicity* Endothelial cell edema and blebbing* Necrosis of type 1 pneumocytes* Proliferation of fibroblast and fibrosis* Hyperplasia and metaplasia of type II pneumocytes* Inflammatory...
Pharmacology
Anti-Neoplastic Agents
42df5375-5026-4824-81fc-7c72d7a13f5a
A policemen foo..a a person ln ing unconscious in iglu lateral position on the road with superficial injury to the face, bruises on the right arm, and injury to the lateral aspect of right knee. Nerve most probably injured:
Femoral nerve
Radial nerve
Common peroneal nerve
Trigeminal nerve
2c
single
Ans. c. Common peroneal nerve Common peroneal nerve (L4, L5, Sl, S2) is the smaller terminal branch of sciatic nerve. The larger terminal branch of sciatic nerve is the tibial nerve. The common peroneal nerve is relatively unprotected as it traverses the lateral aspect of the head of fibula and is easily compressed at ...
Surgery
null
8ea90eae-eb18-4887-9d50-9892e4aa0479
To which of the following events is 'good' outcome in neuroblastoma associated -
Diploidy
N-myc amplification
Chromosome 1 p deletion
Trk A expression
3d
single
null
Pathology
null
833c680b-868a-47d2-a03b-7c9972141b05
HLA B27 histocompatibility antigen is correlated With
Sjogren's disease
Ankylosing spondylitis
Felty's syndrome
Scleroderma
1b
single
REF:HARRISONS PRINCIPLE&;S OF INTERNAL MEDICINE 18TH EDITION
Medicine
Immune system
5ac2cc09-7a22-477e-b98a-6d3c938893ed
Dileufloy's lesion is seen in -
Stomach
Jejunum
Oesophagus
Anus
0a
single
Ans. is 'a' i.e., Stomach Dieulafoy's lesion* Dieulafoy's lesion is a medical condition characterized by a large tortuous arteriole most commonly in the stomach wall (submucosal) that erodes and bleeds.* It can cause gastric hemorrhage but is relatively uncommon. It is thought to cause less than 5% of all gastrointesti...
Anatomy
Abdomen & Pelvis
4e6d7112-235c-455c-9c85-42b882282c27
All the following are complications of streptokinase, except
Joint pain
Intracranial bleed
Anaphylaxis
Hypotension
0a
multi
Ref Harrison 19 th ed pg 1605 Allergic reactions to streptokinase occur in ~2% of patients who receive it. While a minor degree of hypotension occurs in 4-10% of patients given this agent, marked hypotension occurs, although rarely, in association with severe allergic reactions.
Medicine
C.V.S
97597308-a57c-4395-a821-83903e96ee9c
Odontogenic tumors just 1cm away from lower border
Enbloc resection
Hemi mandibulectomy
Enucleation
None
0a
multi
null
Surgery
null
4948ade6-689f-4089-88b0-84ad2c3e878b
A 40-year-old patient is suffering from carotid body tumor. Which of the following is the best treatment for him?
Excision of tumor
Radiotherapy
Chemotherapy
Carotid aery ligation both proximal and distal to the tumor
0a
multi
Best treatment for a 40-year-old patient who is suffering from carotid body tumor is excision of tumor. CAROTID BODY TUMOR TREATMENT Because these tumors rarely metastasizeQand their overall rate of growth is slow, the need for surgical removal must be considered carefully as complication of surgery are potentially ser...
Surgery
Neck
1bfac5aa-b16b-41df-9688-d96e1c7b2270
Following may be seen in the exit wound: DNB 10; NEET 14
Di collar
Abrasion collar
Tattooing
Inveed edges
1b
single
Ans. Abrasion collar
Forensic Medicine
null
af06c382-fa50-4f62-b9d4-bd722954415b
Substance which is not absorbed in the loop of Henle: March 2005
K+
Urea
CI?
Na+
1b
single
Ans. B: Urea The descending pa of the thin segment of the loop of Henle is highly permeable to water and moderately permeable to most solutes and little or no active reabsorption. The thick ascending limb of the loop of Henle reabsorbs about 25% of the filtered loads of sodium, chloride and potassium as well as large a...
Physiology
null
4538d2e9-0987-488f-9dd4-91fdf628e56a
Frequency distribution is studied by -
Histogram
Line diagram
Pie diagram
Ski diagram
0a
single
null
Social & Preventive Medicine
null
281a7260-b0ee-4e90-9e0b-88bd05fb693c
A 28 year old woman, suffers from emotional liability and depression, about 10 days prior to her menses. She repos that once she begins to bleed, she feels back to normal. She also gives a history of premenstrual fatigue, bloating and breast tenderness. What would be the best treatment for the patient?
Evening primrose oil
Vitamin B6
Fluoxetine
Progesterone
2c
single
Fluoxetine is a selective serotonin Reuptake Inhibitor (SSRI) and SSRIs have shown the greatest efficiency in PMS treatment. Premenstrual syndrome (PMS), also called Premenstrual Tension (PMT), is a symptom complex, recognised primarily by cyclic changes, associated with ovulatory cycles. It occurs 7 to 14 days prior t...
Gynaecology & Obstetrics
Disorders of menstruation
dc473812-45a6-4add-a49f-aeecc555e87c
Which of the following statements about 'Multiple Pregnancies' is TRUE?
Fetuses of same gender excludes dichorionicity
Twin Peak Sign is seen in dichorionicity
Thick separating membrane is a feature of monochorionic twins
Chorionicity can be reliably detected only after 16 weeks of gestation
1b
multi
Twin peak or Lambda sign is seen in dichorionic diamniotic twin gestation. In this the chorion and amnion for each twin reflect away from the fused placenta to form an inter twine membrane. A space that exist in the intewine membrane is filled by proliferating placental villi giving rise to twin peak sign. Twin peak si...
Gynaecology & Obstetrics
null
bbcbba60-aa5d-44e9-b34f-5c4146e82733
Protein secreted by odontoblast:
Chitin
Keratin
Collagen
Elastin
2c
single
null
Dental
null
f9401c1c-b9cd-43d5-928a-0cf204326f7f
In hyponatremia following renal failure, serum sodium should be maintained at what levels ?
120 mEq/L
125 mEq/L
130 mEq/L
135 mEq/L
0a
single
Hyponatremia in CKD population is associated with increased moality, but the effect on renal outcome was unknown.. Hyponatremia (serum sodium <120 mEq/L) was associated with excessive volume and volume depletion, measured as total body water by bioimpedance analysis, in diuretic users, but not in diuretic non-users Ref...
Medicine
Fluid and electrolytes
a0ba7c38-42ad-4c8a-8293-a146658bf3ca
True about VSD are all except –
Left to right shunt
Pansystolic mormor
Reverse spliting of S2
Left atrial hypertrophy
2c
multi
Hemodynamics of VSD A VSD results in shunting of oxygenated blood from left to right because left ventricle has more pressure than right → Left to right shunt. Blood flow from left to right ventricle due to high pressure gradient → Pansystolic murmur and systolic thrill. Because left ventricle starts contracting befor...
Pediatrics
null
1d33a6f3-018f-4042-883f-3c1fd7ecd4cc
Rapid change of presbyopic glass is a feature of
Senile cataract
Retinal detatchment
Intumescent cataract
Open angle glaucoma
3d
single
D i.e. Open angle glaucoma Conditions associated with altered refraction Feature Found in Frequent change of presbyopic glasses Open angle glaucoma Q Second sight/ Myopic Shift/Improvement in near vision Senile immature nuclear cataract Fluctuation of refractory error Diabetic cataract Frequent change of glasses Coical...
Ophthalmology
null
2c528ae4-9e61-4789-8d93-3c139d02998b
Alopecia areata is not associated with which of the folllowing condition?
Exclamation sign
Atopy
Pitting nails
Geographical tongue
3d
single
Alopecia areata may be associated with atopy, downs syndrome, vitiligo, pernicious anemia, myxedema , diabetes or hypeension in the family. Sho,1-2 mm fractured hairs can frequently be seen at the active margins of alopecia areata. These hairs are described as exclamation mark hairs because these characteristic hairs f...
Dental
Anatomy of skin
e49161b3-15c9-4e3f-a90b-0d857f39c76c
Risk of mother to child HIV transmission in pregnant woman at the time of delivery, and after delivery in non breast feeding woman is
5-10%
15-30%
10-15%
More than 50%
1b
single
HIV transmission in absence of intervention: MTCT of HIV in developed countries: 20% (15-25%) MTCT transmission of HIV in developing countries: 30% (25-35%)
Social & Preventive Medicine
null
95e3a156-b0ae-4d62-a3dc-23c5864c0cfa
True about receptor potential is?
Due to difference in permability of receptors for different ions
Is propogated
Refractory period of 15-20 sec
Is a graded change
3d
multi
ANSWER: (D) Is a graded changeREF: Textbook of Medical Physiology by Khurana page 1032-1033, Physiology - Prep Manual for Undergraduates, 4th Edition by Vijaya D Joshi page 562, Ganongs 22nd ed p. 123-125When a stimulus excites the receptor, it changes the potential across the membrane of the receptors. This change in ...
Physiology
Nerve Physiology
0c4c9422-b509-440b-9ab9-389aaced86a2
Condition required for autoclave is?
121°C temperature for 20 min
121°C temperature for 15 min
100°C temperature for 60 min
100°C temperature for 90 min
1b
single
Autoclave: Recommended condition- 121–124°C temperature for 15 min at 1.1 bar pressure Alternate: 134–138°C temperature for 3 min at 2.2 bar pressure Hot air oven: 160°C temperature for 120 min or 180°C temperature for 30 min
Microbiology
null
84021fac-4a52-47bd-b87c-70201fc0f5e6
An obese, diabetic patient with hypertension who is also a smoker, currently on anti-hypertensive and OHA drugs presents with complains of apnea during night. Polysomnography reveals 5 apneic episodes and 1 hypoapneic episode in one hour. What will be best next line of management is: (E. REPEAT 2007)
Nasal CPAP
Uvulopharyngopalatoplasty
Mandibular sling
Diet and weight reduction
3d
single
Ref: Harrison's Principles of Internal Medicine. 18th edition, Page 2188Explanation:OSAHS is defined as the coexistence of unexplained excessive daytime sleepiness with at least five obstructed breathing events (apnea or hypopnea) per hour of sleep.EPWORTH SLEEPINESS SCOREHow often are you likely to doze off or fail as...
Medicine
Diabites & Inappropriate Antidiuretic Hormone
e002aab4-2a95-4f63-bca4-bb7c054eb9c3
Blue sclera is seen in -
Alkaptonuria
Osteogenesis imperfect
Down syndrome
Kawasaki syndrome
1b
single
Ans. is 'b' i.e., Osteogenesis imperfect * Blue scleral discoloration is caused by thinning or transparency with resultant visualization of the underlying uvea.* Causes of blue sclera are: Osteogenesis imperfecta, Marfan syndrome, Ehler - Danlos syndrome, Pseudoxanthoma elasticum.
Ophthalmology
Sclera
9edee9c3-3343-4f76-821b-44edb74dacd5
A 3 year graduate MBBS programme was suggested by which committee?
Sundar Committee
Expert Level Committee on Universal Health Coverage
Srivastava Committee
Krishnan Committee
1b
single
HLEG Recommendations High Level Expert Group (HLEG, Planning Commission, GOI) on Universal health Coverage has suggested 3½ year MBBS course for serving rural population HLEG was developed for XII Five Year Plan Rural doctors will be called as ‘Community Health Officers’ 3½ Degree given: B.Sc. Community Health
Social & Preventive Medicine
null
4c00e498-9483-4d46-90e1-05db764595c1
Quinidine exes action on hea by
Ca+ Channel blocker
Kt Channel blocker
Na+ Channel opener
Cl+ Channel opener
1b
single
Refer katzung 11e p 237 * Mechanism of action Like all other class I antiarrhythmic agents, quinidine primarily works by blocking the fast inward sodium current (INa). ... The effect of blocking the fast inward sodium current causes the phase 0 depolarization of the cardiac action potential to decrease (decreased Vmax)...
Pharmacology
Cardiovascular system
0ddd485d-1d97-49b3-8f1a-aceb36b938ba
In the beginning of resuscitation effos, 0.5 mg of epinephrine is administered subcutaneously. Which adrenergic receptors, in which tissues, are responsible for the beneficial effect of epinephrine in this patient?
Alpha-1 receptors in vascular smooth muscle, alpha-2 receptors in the hea, and beta-1 receptors in bronchial smooth muscle
Alpha-1 receptors in vascular smooth muscle, alpha-2 receptors at presynaptic nerve terminals, beta-1 receptors in bronchial smooth muscle
Alpha-1 receptors in vascular smooth muscle, beta-1 receptors in the hea, and beta-2 receptors in bronchial smooth muscle
Alpha-2 receptors in vascular smooth muscle and beta-2 receptors in vascular smooth muscle
2c
single
Epinephrine is a non selective adrenergic agonist and a valuable resuscitative drug because of its effects at multiple adrenergic receptor subtypes. In the treatment of anaphylaxis, epinephrine increases myocardial contractility, accelerates hea rate, causes constriction of vascular smooth muscle, and causes relaxation...
Pharmacology
null
53863cc7-5dfe-4c90-be6a-b0cd962e04da
Residul lung volume increased in
Obesity
Emphysema
Bacterial pneumonia
Idiopatic pulmonary fibrosis
1b
single
(B) Emphysema# FACTORS AFFECTING FRC> FRC Increases with: Increased height Erect position (30% more than in supine) Decreased lung recoil (E.g. emphysema)> FRC Decreases with: Obesity, Muscle Paralysis (especially in supine) Restrictive lung disease (E.g. Fibrosis, Pregnancy) Anaesthesia FRC does not change with age> E...
Medicine
Miscellaneous
912a667d-7314-4e2a-8c61-254829eae221
What is the most probable diagnosis for on the x-ray of a 20 year old female who came with knee swelling
Osteosarcoma
Osteoclastoma
Osteochondroma
None of the above
0a
multi
Sunburst appearance of Osteosarcoma Sunburst appearance is a type of periosteal reaction giving the appearance of a sunburst secondary to an aggressive The sunburst appearance occurs when the lesion grows too fast and the periosteum does not have enough time to lay down a new layer and instead the It is frequently asso...
Orthopaedics
All India exam
3279884b-f16a-455f-80ff-ffdac0268c3e
Which among the following is true about atrial myxoma?
Most common in right atrium
Rarely reoccurs after excision
Distant metastases are seen
More common in males
3d
multi
Atrial myxomas are the most common primary hea tumors, and 75-85% occurs in the left atrial cavity. The most common site of attachment is at the border of the fossa ovalis in the left atrium. Although atrial myxomas are typically benign, local recurrence due to inadequate resection or malignant change has been repoed. ...
Surgery
null
26c725f5-13be-45fd-9f43-928281fb1d69
For the following statements, select whether it is applicable to any or all of the below medications.Inhibition of angiotensin converting enzyme I (ACE I)
hydralazine
enalapril
spironolactone
metoprolol
1b
multi
Enalapril may exert its effect by inhibiting formation of angiotensin II. This lowers systemic vascular resistance. In addition, ACE inhibitors have a natriuretic effect by inhibition of aldosterone secretion. They have been shown to improve mortality and decrease hospitalization in patients with CHF.
Medicine
C.V.S.
a1ae7e34-0cc1-4c25-832a-ad3e869b04bb
Lesion of optic tract causes?
Binasal hemianopia
Bitemporal hemianopia
Homonymous superior quadrantonopia
Homonymous hemianopia
3d
single
Ans. (d) Homonymous hemianopiaRef.: Harrison's 19th ed. /198-199* Unilateral optic nerve lesion: Unilateral blindness* Binasal hemianopia: Bitemporal optic chiasma lesion. Two different lesions compressing the chiasma from the lateral parts.* Bitemporal hemianopia: Binasal retinal damaged optic chiasmal lesion. Commone...
Ophthalmology
Lesions of the Visual Pathway
5a4d3e7d-5358-48ef-b7ac-57e7e7a5b3a8
Who coined term anaesthesia
Moon
Holmes
Morgan
Priestly
1b
single
Oliver Wendell Holmes coined the term anesthesia. In 1846, Holmes coined the word anesthesia. In a letter to dentist William T. G. Moon, the first practitioner to publicly demonstrate the use of ether during surgery, he wrote: "Everybody wants to have a hand in a great discovery. All I will do is to give a hint or two ...
Anaesthesia
General anaesthesia
5794f9a3-3751-4aaa-9a66-c8d595fb3029
A 55-year-old man presents with recurrent epigastric pain. Upper GI endoscopy and gastric biopsy reveal a neoplastic, lymphocytic infiltrate invading glandular tissue. Giemsa staining is positive for Helicobacter pylori. Which of the following is the most likely diagnosis?
Burkitt lymphoma
Marginal zone lymphoma
Follicular lymphoma
Mantle cell lymphoma
1b
single
Diagnosis: Marginal zone lymphoma, MALT lymphoma Marginal Zone Lymphoma is an indolent tumor develop due to chronic B cell stimulation either by H.pylori or Auto immune disorders Translocation (11:18) involved
Pathology
Non Hodgkin Iymphoma
389308bb-d6dc-408b-b364-15fe5627d57a
Maintenance of high urinary pH is important during methotrexate treatment because:
Bladder irritation is reduced
It decreases renal tubular secretion of methotrexate
Leucovorin toxicity is increased in a dehydrated patient
Methotrexate is a weak acid
3d
single
Methotrexate is a weak acid and is reabsorbed in acidic urinary pH. Higher plasma concentration may result in toxicity. Therefore, to decrease the reabsorption through renal tubules, high urinary pH must be maintained.
Pharmacology
null
20c3f14f-2cf7-4952-ab36-08f6f761564a
Which of the following statement is true regarding Atazanavir:-
Effective against only HIV-1
Resistance is due to mutation in codon 50 isoleucine to valine substitution
Decrease cholesterol and triglyceride levels
Combination with ritonavir do not have any advantage
1b
multi
Atazanavir is effective against both against HIV 1 and HIV 2 but NNI are effective only against HIV 1. They do not decrease cholesterol and triglyceride levels. Combination with ritonavir have an advantage due to the phenomenon of Ritonavir boosting. The resistance is due to mutation in codon 50 isoleucine to valine su...
Pharmacology
Anti-HIV Drugs
34b433b0-90ba-447c-ae08-32c3b3aa43a1
Cerebrosides consist mostly of this
Glucose
Galactose
Fructose
Arabinose
1b
single
Both glucocerebrosides and galacto cerebrosides are present however galactocerebrosides are most commonly seen on neural cells and are abundant
Biochemistry
miscellaneous
a4da82ea-fb41-4064-b3d6-4400d4702165
Bence Jone's Protein is: March 2005
Monoclonal heavy chains
Monoclonal light chains
Both of above
None of the above
1b
multi
Ans. B: Monoclonal light chains A Bence Jones protein is a monoclonal globulin protein found in the blood or urine, with a molecular weight of 22-24 kDa. The proteins are immunoglobulin light chains (paraproteins) and are produced by neoplastic plasma cells. They can be kappa (most of the time) or lambda. The light cha...
Pathology
null
2605426c-3123-4d74-83b1-1ffc00aa5543
Risk factors for gonococcal infection is all except
Age > 25 year
Prior or current STDs
New or multiple sexual partners
Lack of barrier modes of protection
0a
multi
Age < 24 years is a risk factor.
Gynaecology & Obstetrics
null
f894dd04-28d7-4d0d-adff-118cfc5cb70a
If a 5–year-old child suddenly develops stridor, which one of the following would be the most likely diagnosis –
Laryngomalacia
Acute laryngo–tracheobronchitis
Foreign body aspiration
Acute epiglottitis
2c
single
null
Pediatrics
null
0d0c73ba-e981-4752-8f1f-8c753874534d
The ability of a screening test to detect "true positives" is known as -
Sensitivity
Specificity
Positive predictive value
Negative predictive value
0a
multi
null
Social & Preventive Medicine
null
859927e4-cb26-4fc8-8245-c2e988870663
Which of the following best defines the "Saccade"-
Voluntary slow eye movements
Involuntary slow eye movement
Abrupt, involuntary slow eye movements
Abrupt, involuntary rapid eye movements
3d
single
Saccades are sudden, jerky conjugate eye movements that occur as the gaze shifts from one object to another. Supranuclear eye movement systems include : Saccadic system Smooth pursuit system Vergence system Vestibular system Optokinetic sysytem Position maintenance system Ref;A.K.Khurana;6th edition; Page no: 341
Ophthalmology
Ocular motility and squint
5231c88b-72d2-458c-84c2-0054e526725b
Inclusion conjunctivitis is caused by-
Trachoma
Pneumococcus
Candida
Neisseria
0a
single
Ans. is 'a' i.e., Trachoma Adult inclusion conjunctivitiso It is a type offollicular conjunctivitis caused by serotypes D to K of chlamydia trachomatis-in sexually active young adults.o The primary source of infection is urethritis in males and cervicitis in females.o Transmission may occur either through contaminated ...
Ophthalmology
Inflammations of Conjunctiva - Infective
0de41bd1-4c73-48eb-80b0-386daafdea24
A 25 years old male smoker presents with high grade fever with chills and severe right sided pleuritic chest pain and cough with expectoration physical examination of the patient is likely to show
Increased percussion sounds
Decreased vocal fremitus
Bronchial breath sounds
Decreased vocal resonance
2c
single
This is the case of pneumonia shows signs of consolidation lung : Reduced thoracic movements. Increased vocal fremitus and vocal resonance. Dull note on percussion. Bronchial breath sounds.
Medicine
null
784abd73-7587-4533-8793-502f594486d9
All except one is continued prior to elective caesarean section in an hypertensive diabetic term gestation, obese female who is a case of chronic aorto iliac obstruction.
Labetalol
Statins
Magnesium sulphate
Heparin
3d
multi
Heparin is stopped 6 hours priorly. Rest all drugs need to be continued till day of surgery.
Anaesthesia
null
38888c1e-f85f-4d38-ab27-3856cdb47cf3
Triple bonds are found between which base pairs
A–T
C–G
A–G
C–T
1b
single
Adenine is always paired with thymine by the formation of two hydrogen bonds. Guanine is always paired with cytosine by the formation of three hydrogen bonds. Thus, the C-G bonds are more resistant to denaturation.
Biochemistry
null
d669b0d5-71b1-495f-9fa3-5c0d2651f676
Which is not an effect of atropine?
Rise of body temperature
Decreased salivary secretion
Bradycardia
Increased A-V conduction
2c
single
ANSWER: (C) BradycardiaREF: KDT 4th Ed p. 94EFFECTS OF ATROPINE:CNS* Stimulates medullary , vasomotor and respiratory center* Depresses vestibular excitation , hence anti motion sickness* Suppresses cholinergic activity in basal ganglia, hence decreases tremor.* High doses may cause cortical excitation , restlessness ,...
Pharmacology
Anti Cholinergic