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135
a7fe280b-34b8-4a85-9a19-dde598ba89a2
MHC restriction is a pa of all except aEUR'
Antiviral cytotoxic T cell
Antibacterial helper T cell/cytotoxic cells
Allograft rejection
Autoimmune disorder
3d
multi
Autoimmune disorder Major histocompatibility complex : Major histocompatibility complex, also called the human leucocyte antigen (HLA) complex is a 4 megahase region on chromosome 6. This region is densely packed with genes. These genes encodes two major proteins or antigens i.e., MHC I & MHC II. These proteins play an...
Pathology
null
6025c13b-9771-4204-a4b0-6b192e535d66
During cardiac imaging the phase of minimum motion of hea is:
Late systole
Mid systole
Late diastole
Mid diastole
3d
single
D i.e. Mid diastole- During cardiac imaging (such as MRI, CT, electron beam tomography), mid diastolic phase (or diastasis) of cardiac cycle is usually (but not always) associated with lowest (minimum) mean motion of hea.Q- Optimum phase (i.e. with minimum cardiac motion) for cardiac and coronary vessel imaging is mid-...
Physiology
null
8f18a81d-6806-400d-9cf4-ec61e03f6322
Mandibular nerve does not supply:?
Buccinator
Masseter
Tensor tympani
Temporalis
0a
single
A. i.e. Buccinator
Anatomy
null
d5d03cd8-055b-49bf-9b2d-4b8dc3fd6b4d
A 68-year-old man is admitted to the coronary care unit with an acute myocardial infarction. His postinfarction course is marked by congestive hea failure and intermittent hypotension. On the fouh day in hospital, he develops severe midabdominal pain. On physical examination, blood pressure is 90/60 mm Hg and pulse is ...
Barium enema
Upper gastrointestinal series
Angiography
Ultrasonography
2c
multi
In the absence of peritoneal signs, angiography is the diagnostic test of choice for acute mesenteric ischemia. Patients with peritoneal signs should undergo emergent laparotomy. Acute mesenteric ischemia may be difficult to diagnose. The condition should be suspected in patients with either systemic manifestations of ...
Anaesthesia
Preoperative assessment and monitoring in anaesthesia
3c5f5bd3-3837-4d04-a563-59fc07cbd6c6
Drugs undergoing acetylation include all except:
Dapsone
Metoclopramide
Procainamide
INH
1b
multi
Ans. B. MetoclopramideAcetylation by N-acetyl transferases (NAT)e.g, S - SulfonamidesH - HydralazineI - IsoniazidP - Procainamide, PASD - DapsoneC - Clonazepam, Caffeine
Pharmacology
General Pharmacology
bda5a250-7d66-4377-9fd1-952db0a9f251
A group of expes discussing a topic in front of the audience without any specific order. This mode of communication is known as: September 2008
Panel discussion
Group discussion
Team presentation
Symposium
0a
single
Ans. A: Panel discussion In panel discussion there is a chairman/moderator and 4-8 speakers. Each speaker prepares separately, the other speakers hear one another for the time at the session itself. Panel discussions, however, differ from team presentations. Their purpose is different. In a team presentation, the group...
Social & Preventive Medicine
null
7ae4d04b-7e5e-4455-abcb-068b61031179
Starvation and diabetes mellitus can lead on to ketoacidosis which of the following features is in our of ketoacidosis due to diabetes mellitus.
Increase in glucagon/insulin ratio, increased CAMP and increased blood glucose
Decreased insulin, increased free fatty acid which is equivalent to blood glucose
Decreased insulin, increased free fatty acid which is not equivalent to blood glucose
Elevated insulin and free fatty acid, equivalent to blood glucose
0a
single
A i.e. Increase in glucagons/ insulin ratio, increased C- AMP & increased blood sugar.In diabetes little glucose is oxidized as fuel, except by the brain. The rest of tissues burn a large amount of fat, paicularly the liver where the amount of acetyl COA formed from fatty acids exceeds the capacity of the tricarboxylic...
Biochemistry
null
2773c7ba-b414-43d6-809b-51fb6e2c106e
ARDS true?
Type 2 respiratory failure
Lung compliance decreased
Increase in diffusion capacity
none
1b
multi
ARDS is a clinical syndrome of severe dyspnoea of rapid onset, hypoxaemia and diffuse pulmonary infiltrates leading to respiratory failure.ARDS is characterised by Po2/Fio2(inspiratory O2 fraction)<200 mmHg.There will be no hypercapnia, so the patient will have type 1 respiratory failure. There will be a stiff-lung sy...
Medicine
null
f31e136f-03b2-4c6c-ac9a-1b44363e8c93
Hypeension is seen with all except-
Erythropoitin
Cyclosporine
NSAID
Levodopa
3d
multi
Ans. is d i.e., Levodopa Drug causing hypeension Cocaine MAO inhibitors Oral contraceptives Clonidine withdrawl Tricyclic antidepressants Cyclosporine Glucocoicoids Rofecoxib (NSAID) Erythropoietin Valdecoxib (NSAID) Sympathomimetics
Pharmacology
null
602956cf-ddb9-4e59-b5d1-c0ac6568d3da
Beta 2 agonist used in rescue therapy in acute respiratory conditions are all except?
Formoterol
Salbutamol
Bambuterol
Ketotifen
3d
multi
Ans. is 'd' i.e., Ketotifen Formoterol, Salbutomol and bambuterol are p 2 agonists. o Ketotifen is a mast cell stabilizer.
Pharmacology
null
596a9bae-2d55-449d-9c81-2f0e7154a1eb
The post mortem report in case of death in police custody should be recorded as
Tape recording
Video recording
Photographic recording
All
1b
multi
Ans. b (Video recording). (Ref. Parikh, FMT, 5th ed., 130)Installation of video camera in jail and recording of postmortem in case of death in police custody is according to human rights.
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
23a18676-636e-4059-a12b-c8b65f9ee614
Reversible loss of polarity with abnormality in size and shape of cells is known as?
Metaplasia
Anaplasia
Dysplasia
Hyperplasia
2c
single
Dysplasia is reversible Anaplasia is irreversible
Pathology
null
78001841-a752-480d-b11c-941bc1a1fac3
During autopsy for virology study which agent is used for storing tissue: NEET 14
Sodium chloride
Alcohol
Rectified spirit
50% glycerine
3d
single
Ans. 50% glycerine
Forensic Medicine
null
4a9525b2-901b-4f48-a4e9-e720ee523694
The protective bacterium in the normal vagina is:
Peptostreptococcus
Lactobacillus
Gardenella vaginalis
E. coli
1b
single
Vagina has inhabitant bacteria called as Doderleins bacteria which is a lactobaccilli, and converts the glycogen present in vaginal epithelium into lactic acid. Thus, pH of the vagina is acidic The pH of the vagina in an adult woman is 4 -5.5 with an average of 4.5. The pH of vagina varies with age — for further detail...
Gynaecology & Obstetrics
null
31b43938-594a-4d44-a3a6-6a28058171fb
Bence jones proteinuria is derived from?
Alpha globulins
Light chain globulins
Gamma globulins
Delta globulins
1b
single
Ans. (b) Light chain globulins(Ref: R 9th/pg 598-602)Excretion of light chains in the urine has been referred to as Bence Jones proteinuria.Light chains includes k and l (kappa and lambda)
Pathology
Misc. (W.B.C)
8b1e7f01-b79f-4f24-a759-3f3fed9c1978
Which of the following drugs used to treat type II diabetes mellitus causes weight loss:
Metformin
Glimepiride
Repaglinide
Gliclazide
0a
single
null
Pharmacology
null
27eb5249-ce63-4440-92ac-25f6e3eb6356
Pradhan mantra swasthya suraksha yojana was launched in:
2003
2006
2007
2008
1b
single
Pradhan mantra swasthya suraksha yojana was approved in 2006 with the objective of correcting imbalances in availability of affordable teiary level healthcare in the country. Ref: National Health Programmes in India, J.Kishore, 10th edition pg: 84
Social & Preventive Medicine
null
0f896d5f-c39d-4a50-a1aa-9ed2a58fab4e
Which of the following measures sensitivity: September 2011
True negatives
True positives
False positives
False negatives
1b
multi
Ans. B: True positives Sensitivity denotes true positives
Social & Preventive Medicine
null
a5907673-ff1e-457a-9a0e-51229dcc8d8a
Caput succedaneum in a newborn is: Karnataka 07
Collection of blood under the pericranium
Collection of sero-sanguineous fluid in the scalp
Edema of the scalp due to grip of the forceps
Varicose veins in the scalp
1b
single
Ans. Collection of sero-sanguineous fluid in the scalp
Forensic Medicine
null
cf39481b-9bf0-494c-bce7-e8c914f1b05e
Zero order kinetics is seen in all except
High dose salicylates
Phenytoin
Ethanol
Methotrexate
3d
multi
Zero order kinetics is seen in high dose of salicylates,ethanol and phenytoin. Ref-KDT 6/e p31
Anatomy
General anatomy
2d7a877b-f78b-42b3-8c67-8ea86bb2105a
In a normal healthy person the arterial oxygen is considered satisfactory if SPO2 is more than
80
85
90
Any of the above
2c
multi
Ans. c (90) (Ref H-17th/l590-91; pg. A-15)In a normal healthy person the arterial oxygen is considered satisfactory if SP02 is more than 90.Arterial O2 tensionPaO212.7 +- 0.7 kPa (95 +- 5 mm Hg)Arterial CO2 tensionPaCO25.3 +- 0.3 kPa (40 +- 2 mm Hg)Arterial O2 saturationSaO20.97 +- 0.02 (97 +- 2%)Arterial blood pHpH7.4...
Medicine
Respiratory
4e1715fe-0bc3-494e-b6eb-2d4617245aef
A 40-year-old man presents with 5 days of productive cough and fever. Pseudomonas aeruginosa is isolated from a pulmonary abscess. CBC shows an acute effect characterized by marked leukocytosis (50,000/mL) and the differential count reveals shift to left in granulocytes. Which of the following terms best describes thes...
Leukemoid reaction
Leukopenia
Myeloid metaplasia
Neutrophilia
0a
single
Circulating levels of leukocytes and their precursors may occasionally reach very high levels (>50,000 WBC/mL). These extreme elevations are sometimes called leukemoid reactions because they are similar to the white cell counts observed in leukemia, from which they must be distinguished. The leukocytosis occurs initial...
Pathology
Basic Concepts and Vascular changes of Acute Inflammation
614f4210-d584-4e21-b2e3-6472f398f00a
A patient present with dysphagia of 4 weeks duration. Now he is able to swallow liquid food only. Which of the following is the one investigation to be done:
Barium studies are the best to be done
Upper GI endoscopy is to be done
CT scan is needed
Esophageal manometry
1b
multi
Answer is B (Upper GI endoscopy is to be done) The patient is presenting with new onset dysphagia for solids alone (able to swallow liquids). This suggests dysphagia due to mechanical obstruction (carcinoma, stricture, web) which is best diagnosed by endoscopy. Note: Barium swallow is the recommended initial investigat...
Medicine
null
b4f990b1-cddf-4802-b986-10c61383fcb1
Inhalation of fungal spores can cause primary lung infections. Of the following organisms, which one is most likely to be associated with this mode of transmission?
C. immitis
S. schenckii
C. albicans
T. tonsurans
0a
single
C. albicans and Candida tropicalis are opportunistic fungi, and as part of the normal flora are not transmitted by inhalation. C. immitis is a dimorphic fungus and inhalation of the spores transmits the infection. Sprothrix is also a dimorphic fungus but its portal of entry is cutaneous. Trychophyton is a dermatophyte ...
Microbiology
Mycology
eac1c406-7e99-4957-9684-2dff2b6d9f07
Fleeting skin lesions are often present in patients with:
Viral hepatitis B
Acute cholangitis
Viral hepatitis A
Carcinoma head of pancreas
0a
single
Fleeting skin lesions are often presents in patients with hepatitis B. Ref: Schiff's diseases of liver, Edition -11, Page - 3.
Medicine
null
95016012-c708-472e-bc82-ca45706c8de4
In which of the following locations, Carcinoid tumor is most common
Esophagus
Stomach
Small bowel
Appendix
3d
multi
carcinoid tumour commonly occurs in appendix(45%),ileum(25%),rectum(15%).other sites are(15%)other pas of GIT ,bronchus, and testis SRB,5th,877.
Surgery
Head and neck
e77a5910-d85b-445f-98bf-906ab456b458
S100 is a marker used in the diagnosis of all Except
Melanoma
Schwannoma
Histiocytoma
Basal cell cancer
3d
multi
Acidic protein, 100% Soluble in ammonium sulfate at neutral pH (derivation of name) S100 protein family is multigenic group of nonubiquitous cytoplasmic EF-hand Ca2+-binding proteins, sharing significant structural similarities at both genomic and protein levels; S100 protein family has 24 known human members each code...
Pathology
General pathology
bdae4721-695e-4983-bc69-4012c1a87907
A Patient who is on antihypertensive drug develops a dry cough. Which of the following drug might be responsible for the condition:
Diuretics
ACE inhibitors
Calcium channel blockers
Beta blockers
1b
single
The angiotensin-converting enzyme normally helps in conversion of angiotensin I to angiotensin II, which acts as a vasoconstrictor in case of hypovolemia. In addition to that, ACE also helps in the breakdown of bradykinin. When ACE inhibitors (captopril) are given, it inhibits ACE and in addition inhibits the breakdown...
Pharmacology
null
95952308-e34f-4e57-b1fc-b7227ca74170
Mad Cow disease (Spongiform disease) occurs due to
C J virus
Arena Virus
Kuru Virus
Parvo Virus
0a
single
Mad cow disease or bovine spongiform encephalopathy i.e. Caused by “prions” “PRIONS” are unconventional transmissible agents, proteinaceous in nature.” Diseases caused by prions are Kuru Creutzfeldt Jakob Disease. Gerstmann Straussler Scheinker Syndrome Fatal Familial Insomnia. Scrapie Of Sheep Transmissible Encephalop...
Microbiology
null
401f06f5-0cc0-49c8-ab84-8b432053a073
Schwann cells are derived from:
Neural crest cells
Endoderm
Mesoderm
Ectoderm
0a
single
null
Surgery
null
591db8ae-5677-413e-af48-48e4111b7dbc
A patient on lithium therapy was found to be hypeensive also. Which of the following antihypeensive drugs is contraindicated in a patient on lithium therapy in order to prevent toxicity?
Clonidine
Beta blockers
Calcium channel blockers
Diuretics
3d
single
Diuretics (thiazide, furosemide) by causing Na+ loss promote proximal tubular reabsorption of Na+ as well as Li+ --plasma levels of lithium rise. ref : KD Tripati 8th ed.
Pharmacology
Central Nervous system
72f39ade-71df-4733-9ef5-cce8ff78a9f1
In marasmus, which of the following is not seen?
Edema
Voracious appetite
Hepatomegaly not seen
Child is active
0a
single
Edema is a feature of Kwashiorkor, not seen in marasmus. Kwashiorkor Marasmus Edema Present absent appetite poor Voracious appetite CNS involvement apathy Active child Hepatomegaly seen Not seen Skin and hair changes More common Less common
Pediatrics
FMGE 2019
bcaf945c-3adc-4287-ac79-628fdabe0155
A 23-year-old woman presents with a rubbery, freely movable 2-cm mass in the upper outer quadrant of the left breast. A biopsy of this lesion would most likely histologically reveal
Large numbers of neutrophils
A mixture of fibrous tissue and ducts
Large numbers of plasma cells
Necrotic fat surrounded by lipid-laden macrophages
1b
multi
The most common benign neoplasm of the breast is fibroadenoma, which typically occurs in the upper outer quadrant of the breast in women between the ages of 20 and 35. These lesions originate from the terminal duct lobular unit and histologically reveal a mixture of fibrous connective tissue and ducts. Clinically, fibr...
Pathology
miscellaneous
924c74cd-b716-4189-a874-37e201803f6d
Most common pa of larynx involved in TB ?
Anterior
Posterior
Middle
Anywhere
1b
single
Ans. is 'b' i.e., Posterior Essential otolaryngology 2"d/e p. 1139] Disease affects the posterior third of larynx more commonly than anterior pa. The pas affected in descending order of frequency are :- i) Interarytenoid fold, ii) Ventricular band, iii) Vocal cords, iv) Epiglottis.
ENT
null
95117632-48a6-406d-a182-13181792e521
Pyogenic granuloma is associated with
Gastric adenocarcinoma
Pseudomonas infection
Ulcerative colitis
Intestinal tuberculosis
2c
single
Pyogenic granuloma is a misnomer as there is no granuloma. It is a benign vascular lesion that bleeds easily on trauma. It is associated with Inflammatory Bowel disease (Ulcerative colitis > Crohn's disease).
Dental
null
562a26c1-857f-41c3-9f46-95d0f18e7cba
Epithelial rests of Malassez are found in
Pulp
Gingiva
Periodontal Ligament
Alveolar mucosa
2c
single
null
Dental
null
5a099680-e853-4b92-9d5c-de8c86f55891
Muscle relaxant used in renal failure -
Ketamine
Atracurium
Pancuronium
Fentanyl
1b
single
As Atracurium and Cis-atracurium are inactivated by Hoffman's elimination, they are the muscle relaxants of choice for both liver and renal failure.
Anaesthesia
Muscle relaxants
07cb00a8-27aa-4917-a9b9-369c38b87aac
Ramachandran is on the surgical ward with non-seminomatous tumor of testis and more than 4 retroperitoneal lymph nodes involved. You are the resident who is making a decision about fuher management. The treatment include all of the following, except:
Retroperitoneal Lymph Node Dissection (RPLND)
Inguinal orchiectomy
Chemotherapy
Radiotherapy
3d
multi
Inguinal orchiectomy with high ligation of the cord at the internal ring is the initial management of testicular tumour. Multi Agent chemotherapy and followed by surgical resection is one modality of treatment. Ref: Bailey & Love, 25th Edition, Page 1269.
Surgery
null
0f52a203-4d3d-4fee-b3c2-ee98ee03fe10
A 34-year-old female has a history of intermittent episodes of severe abdominal pain. She has had multiple abdominal surgeries and exploratory procedures with no abnormal findings. Her urine appears dark during an attack and gets even darker if exposed to sunlight. The attacks seem to peak after she takes erythromycin,...
Heme
Creatine phosphate
Cysteine
Thymine
0a
multi
The patient has acute intermittent porphyria, which is a defect in one of the early steps leading to heme synthesis. The buildup of the intermediate that cannot continue along the pathway leads to the dark urine, and it turns darker when ultraviolet (UV) light interacts with the conjugated double bonds in the molecule....
Biochemistry
Proteins and Amino Acids
77dbd24c-97be-40ee-9fee-cdd9f1db9137
Most common type of hypospadias is: September 2011
Glandular
Penile
Coronal
Perineal
0a
single
Ans. A: Glandular Glandular hypospadias is common and does not usually require treatment Hypospadias: The external meatus opens on the underside of the penis or the perineum, and the inferior aspect of the prepuce is poorly developed (hooded prepuce) Meatal stenosis occurs Bifid scrotum 6 - 10 months of age is the best...
Surgery
null
88583589-3126-49ce-b502-07c7fd8f5c63
In a subclan aery block at outer border of 1st rib, all of the following aeries help in maintaining the circulation to upper limb, EXCEPT?
Subscapular aery
Superior thoracic aery
Thyrocervical trunk
Suprascapular aery
1b
multi
A rich anastomosis exists around the scapula between branches of subclan aery (first pa) and the axillary aery (third pa). This anastomosis provides a collateral circulation through which blood can flow to the limb when the distal pa of subclan aery or the proximal pa of axillary aery is blocked. Scapular anastomoses o...
Anatomy
null
819417b2-a1f3-4434-a377-9f1f50574b12
Lymphatics of suprarenal gland drain into lymph nodes -
Internal iliac
Para-aortic
Superficial inguinal
Coeliac
1b
single
Suprarenal glands drain into para-aortic nodes.
Anatomy
null
f6d11bc7-a1c9-4b8d-b8aa-416d1a2b0a18
All of the following can be involved in an injury to the head of the fibula, EXCEPT:
Anterior tibial nerve
Common peroneal nerve
Superficial peroneal nerve
Tibial nerve
3d
multi
The common peroneal nerve is extremely vulnerable to injury as it winds around the neck of the fibula. At this site, it is exposed to direct trauma or is involved in fractures of the upper pa of the fibula. While passing behind the head of the fibula, it winds laterally around the neck of the bone, pierces peroneus lon...
Anatomy
null
819f97b4-d137-4e7e-a425-3503a6e0c4ab
Pain felt between great toe and 2nd toe is due to involvement of which nerve root -
L5
S2
S1
S3
0a
single
First web space of foot is supplied by deep peroneal nerve (L5)
Anatomy
null
b6b26951-01dc-442f-ae96-db59e03a0aa9
Which of the following is non-competitive inhibitor of intestinal alkaline phosphatase?
L-Alanine
L-Tyrosine
L-Tryptophan
L-Phenylalanine
3d
single
Ans. d (L-Phenylalanine) (Ref. Biochemistry by Vasudevan, 4th ed., 57; 5th ed., 55-56)ALKALINE PHOSPHATASE# The pH optimum for the enzyme reaction is between 9 and 10.# It is activated by magnesium and manganese.# Zinc is a constituent ion of ALR# It is produced by osteoblasts of bone, and is associated with the calcif...
Biochemistry
Enzymes
bb5bb631-ba53-4cec-9ff0-64ed67ce022e
Mondors disease is:
Migratory thrombophlebitis seen in pancreatic Ca
Thromboangitis obliterans
Thrombosis of deep veins of the leg
Thrombophlebitis of superficial veins of breast
3d
single
Ans: D (Thrombophlebitis of superficial veins of breast) Ref: Bailey dt Love's Short Practice of Surgery, 25th Edition,833-4Explanation:Mondor's diseaseThrombophlebitis of the superficial veins of the breast and anterior chest wallCan also involve armCauseIdiopathicClinical featuresThrombosed subcutaneous vessel , usua...
Surgery
Miscellaneous (Breast)
c2831b92-d8ad-4873-a0ea-17f2078f9d75
Treatment of Choice in Sleep Apnea Syndrome:
Continuous positive pressure ventilation.
Sedatives.
Antidepressants.
Antiepileptics
0a
single
(A) Continuous positive pressure ventilation# Sleep apnea: Sleep apnea is a sleep disorder characterized by pauses in breathing during sleep. Each episode, called an apnea, lasts long enough so that one or more breaths are missed, and such episodes occur repeatedly throughout sleep.> The standard definition of any apne...
Psychiatry
Miscellaneous
e60b7a7c-e773-4fef-a983-247ce49a9fb7
Rectal polyp most commonly presents as
Obstruction
Bleeding
Infection
Changes into malignancy
1b
single
.LOWER GI BLEED- * Bleeding in the GIT below the level of the ligament of Treitz. * Normal faecal blood loss is 1.2 ml/day. A loss more than 10 ml/day is significant.* Angiodysplasia. * Diveicular disease - commonest cause in Western countries. * Tumours of colon or small bowel. * Anorectal diseases--Haemorrhoids, fiss...
Surgery
G.I.T
58742f0f-2e9e-4d60-a741-11f0591727ff
Ulipristal acetate is a/an:
GnRH agonist
Androgen antagonist
Selective estrogen receptor modulator
Selective progesterone receptor modulator
3d
single
Ans. is d, i.e. Selective progesterone receptor modulatorRef: Harrison's Principles of Internal medicine 19th/ed, p2391Ulipristal acetate (trade name Ella One in the European Union, Ella in the US for contraception, and Esmya for uterine fibroid) is a selective progesterone receptor modulator (SPRM).PharmacodynamicsAs ...
Gynaecology & Obstetrics
Physiology & Histology
007d5aaa-28aa-46a0-b9a1-b410630d4bb5
A patient presented with ahritis and purpura. Laboratory examination showed monoclonal and polyclonal cryoglobulins. Histopathology showed deposits of cryoglobulins around the vessels. The patient should be tested for which of the following ?
HBV
HCV
EBV
Parvovious
1b
single
Hepatitis C This is caused by an RNA flavivirus. Acute symptomatic infection with hepatitis C is rare. Most individuals are unaware of when they became infected and are identified only when they develop chronic liver disease. Eighty per cent of individuals exposed to the virus become chronically infected and late spont...
Medicine
G.I.T
1dfe0a51-259c-4aad-8ae2-f94640af28c7
All of the following structures passes through the Alcock canal, EXCEPT:
Internal pudendal vein
Internal pudendal nerve
Internal pudendal aery
Obturator internus muscle
3d
multi
Alcock canal or pudendal canal stas from the lesser sciatic notch and runs forward on the medial surface of the ischial tuberosity up to the pubic arch where it is continuous with the deep perineal pouch. Contents of the pudendal canal are:Pudendal nervePudendal aery and veinWithin the canal pudendal nerve give rise to...
Anatomy
null
7a26e088-4af9-4d66-925f-e4e91d76f6ca
Marfans Syndrome affecting eyes, skeletal system, and the cardiovascular system is caued by the mutation in the gene
Fibrillin 1
Fibrillin 2
Fibulin
Elastin
0a
single
Marfan Syndrome Is Caused by Mutations in the Gene for Fibrillin-1. It is inherited as an autosomal dominant trait. It affects the eyes (eg, causing dislocation of the lens, known as ectopia lentis), the skeletal system (most patients are tall and exhibit long digits and hyperextensibility of the joints), and the cardi...
Biochemistry
miscellaneous
62ef7333-9fb0-4988-a7e7-9dccd56f784c
RNA primer is synthesized by -
Topoisomerase
Helicase
DNA primase
DNA ligase
2c
single
Ans. is 'c' i.e., DNA primase ProteinFunctionDNA polymerasesDeoxynucleotide polymerizationHelicasesProcessive unwinding of DNATopoisomerasesRelieve torsional strain that results from helicase-induced unwindingDNA primaseInitiates synthesis of RNA primersSingle-strand binding proteinsPrevent premature reannealling of ds...
Biochemistry
Transcription
611d453b-6d05-4abc-a471-5760f6d99806
Biochemical analytes measured in the triple test are all the following Except
hCG
AFP
Unconjugated estriol
Inhibin A
3d
multi
Second-Trimester ScreeningPregnancies with fetal Down syndrome are characterized by lower maternal serum AFP levels--approximately 0.7 MoM, higher hCG levels--approximately 2.0 MoM, and lower unconjugated estriol levels--approximately 0.8 MoM. This triple test can detect 61 to 70 percent of Down syndrome.Levels of all ...
Gynaecology & Obstetrics
Diagnosis in obstetrics
f40a69ac-3908-4578-9738-88b2db21a8e7
A preterm baby is born with synchronised upper chest movement, minimal nasal flare, expiratory grunting heard by the stethoscope, but has no chest or xiphoid retractions. The Silverman score is:
1
2
3
4
1b
single
The Silverman Anderson retraction score of respiratory distress syndrome (RDS): Upper chest Lower chest Xiphoid retraction Nares dilatation Expiratory grunt Grade 0 Synchronised No retraction None None None Grade 1 Lag on inspiration Just visible Just visible Minimal By stethoscope Grade 2 See-saw Marked Marked Marked ...
Pediatrics
null
5b431bce-c54d-41fa-9bfa-8f24dcfc0115
Bacteriostatic antitubercular drug among the following is :
Isoniazid
Rifampicin
Streptomycin
Ethambutol
3d
single
null
Pharmacology
null
62409778-b511-41d6-b92f-516152bca1a1
Yoke muscle pair is
Rt LR and Rt MR
Rt so and Lt Io
Rt LR and Lt MR
All the above
2c
multi
Right lateral rectus and left medial rectus. Yolk muscles are pair of muscles one from eye which contracts simultaneously during version movement.
Ophthalmology
null
f2db47da-2a9b-4244-ab72-7fb372b1fa70
Causes of restrictive cardiomyopathy are -
Amyloid
Sarcoidosis
Storage disease
All of the above
3d
multi
Restrictive cardiomyopathy is characterised by a primary decrease in ventricular compliance , resulting in impaired ventricular filling during diastole. Restrictive cardiomyopathy can be idiopathic or associated with systemic disease that also happen to affect the myocardium for example radiation fibrosis, amyloidosis,...
Pathology
Cardiovascular system
4aed3cb7-f6b2-4bda-b2c0-1230c3e61e34
3-year-old child comes in ER with Hv'o vomiting, loose watery motion for 3 days, on examination, the child was drowsy, sunken eye. Hypothermia and skin pinch take time to revert back, diagnosis
No dehydration
Mild dehydration
Some dehydration
Severe dehydration
3d
single
on  A child with severe dehydration will have at least two of the following four signs: sensorium is abnormally sleepy or lethargic, sunken eyes, drinking poorly or not at all, and a very slow skin pinch. A child with some signs of dehydraon will have two of the following: restlessness or irritability, sunken eyes, dri...
Pediatrics
null
f68d215d-20f5-4c82-a386-02445dc44ebc
A 50 years old lady presented with lump in the left breast, which has developed suddenly in weeks. Perimenstrual symptoms are present. No associated family history. On examination, the lump is well circumscribed, fluctuant, 1.5 cm oval in shape. Most likely diagnosis:
Breast cyst
Galactocele
Fibroadenoma
Breast cancer
0a
single
Fibroadenoma - it occurs in 2nd to 3rd decade of life Galactocele - it occurs in 3rd to 4th decade of life. Breast cancer - there is no associated family history and lump has developed suddenly hence breast cancer is ruled out. Breast cyst - it occurs in 5th to 6th decade of life. Examination revealed fluctuant lesion ...
Surgery
Breast
33bfa0d9-46a8-40c3-a99d-9b701eed3773
HIV can -
Cross blood brain barrier
RNA virus
Inhibited by 0.3% H2O2
Thermostable
0a
single
it can cross blood brain barrier and cause cns infection REF:ANANTHANARAYANAN TEXT BOOK OF MICROBIOLOGY 9EDITION PGNO.576
Microbiology
Virology
e7ad538e-9273-4e0b-87b2-bab411a372ca
Heamorrhagic external otitis media is caused by
Influenza
Proteus
Streptococcus
Staphylococcus
0a
single
Otitis externa haemorrhagica It is characterized by for mation of haemorrhagic bullae on the tympanic membrane and deep meatus. It is probably viral in origin and may be seen in influenza epidemics. The condition causes severe pain in the ear and blood-stained discharge when the bullae rupture. Treatment: with analgesi...
ENT
Ear
bf962e59-dbe7-43f8-a366-6db035e81c1f
A 7 year old male patient presents to the clinic for routine dental examination and has history of frequent snacking and sugary beverages. Intraoral examination shows multiple pit and fissure caries and subsurface enamel porosity manifesting as milky white opacity. Tactile probing should not be used in this case becaus...
Insertion of the explorer into the suspected lesion inevitably disrupts the surface layer covering very early lesions, thereby eliminating the possibility for remineralization of the decalcified area
Probing of lesions and suspected lesions results in the transport of cariogenic bacteria from one area to another
Frank lesions requiring restoration are generally apparent visually without the need for probing.
It may induce spontaneous bleeding
3d
multi
Traditionally, dentists have relied upon a visual-tactile radiographic  procedure  for  the detection  of  dental caries. This procedure involves the visual identification of demineralized  areas  (typically  white  spots)  or  suspicious pits or fissures and the use of the dental explorer to determine the  presence of...
Dental
null
418561b6-f3f8-426e-8516-cb4104e280fb
Most dangerous paicles causing pneumoconiosis are of size
A. 1-5 micron
B. <1 micron
C. 5-15 micron
D. 10-20 micron
0a
single
In pneumoconiosis, the most dangerous paicles range from 1-5 micron in diameter, because they may reach the terminal small airway and settle in there lining notes The solubility and cytotoxicity of paicles ,modify the nature of pulmonary response
Anatomy
Respiratory system
af2763f0-33d6-4d62-b91a-a1808160df66
Calculate the deficit for a 60 kg person,with Hb - 5 g/dl add 1000 mg for iron stores.
1500
2500
3500
4000
1b
single
Iron deficit = Bodyweight(kg) x 2.3 x (15 - Hb) + 1000       = 60 x 2.3 x (15 - 5) + 1000       = 2380 (close to 2500)
Medicine
null
0fe4c348-ea07-4893-836e-83b4fccf6b45
Which of the following is not a cause of glomerular proteinuria?
Diabetes Mellitus
Amyloidosis
Multiple myeloma
Nil Lesion
2c
single
Multiple myeloma is characterized by tubular proteinuria. The Bence Jones proteins induce tubular damage Increased beta-2-microglobulin levels in urine is an prognostic indicator of Multiple myeloma Diabetes Mellitus and amyloidosis lead to damage to basement membrane of the kidney leading to glomerular proteinuria in ...
Medicine
Nephrology
2be6a760-0e08-45a1-a92d-01673c4f4619
Which of the following does not cause Insulin release-
Rosiglitazone
Nateglinide
Glimipiride
Tobutamide
0a
single
Ans. is 'a' i.e., Rosiglitazone o Oral hypoglycemic drugs may be divided into two groups. 1. Group 1 These drugs reduce plasma glucose by stimulating insulin production, therefore called insulin secretogogues. Hypoglycemia is a well known side effect. Examples are: i) Sulfonylureas: first generation (chlorpropamide, to...
Pharmacology
null
1e743463-1cfa-471e-b6ce-7afc105df17d
Which of the following endocrine tumors is most commonly seen in MEN I ?
Insulinoma
Gastrinoma
Glucagonoma
Somatotrophinoma
1b
single
In MEN 1 : * Gastrinoma (>50%) * Insulinoma (10-30%) * Glucagonoma (<3%) * Somatotrophinoma (25%) Reference : page 2336 Harrison's Principles of Internal Medicine 19th edition
Medicine
Endocrinology
a6a80e21-ef83-4e66-8e5b-2c6f53af99ef
The following is the least useful investigation in multiple myeloma :
ESR
X-Ray
Bone scan
Bone marrow biopsy
2c
single
Answer is C (Bone scan) Bone scans are least useful for diagnosis of Multiple Myeloma. Cytokines secreted by myeloma cells suppress osteoblastic activity therefore typically no increased uptake is observed. In multiple myeloma the osteohlastic response to bone destruction is negligible. The bone scan therefore is often...
Medicine
null
c9e6d495-1190-492f-b867-98f0ca24ed06
Most common organism causing ventilator associated pneumonia -
Legionella
Pneumococcus
Pseudomonas
Coagulase negative staphylococcus
2c
single
null
Microbiology
null
226c17a9-13fe-4496-bc2e-5aabce4fef1c
A 2-week-old baby is irritable and feeding poorly. On physical examination, the infant is irritable, diaphoretic, tachypneic and tachycardic. There is circumoral cyanosis, which is not alleted by nasal oxygen. A systolic thrill and holosystolic murmur are heard along the left sternal border. An echocardiogram reveals a...
Atrial septal defect
Coarctation of aoa, preductal
Patent ductus aeriosus
Truncus aeriosus
3d
multi
Truncus aeriosus refers to a common trunk for the origin of the aoa, pulmonary aeries and coronary aeries. It results from absent or incomplete paitioning of the truncus aeriosus by the spiral septum during development. Most infants with persistent truncus aeriosus have torrential pulmonary blood flow, which leads to h...
Pathology
Cardiac disorders
a7d937b5-0a4b-4c68-8e93-e4b0d74ab5f5
prophylaxis for Pneumocystis carinii is indicated in HIV positive patents When CD4 count is-
<300 cells/mm3
< 200 cells / mm3
< 100 cells/mm3
< 50 cells / mm3
1b
single
Low CD4 count correlated with risk of PCP (p < 0.0001); 79% had CD4 counts less than 100/microl and 95% had CD4 counts less than 200/microl. Bacterial pneumonia has been linked to several HIV-related factors, including CD4 counts, having an uncontrolled viral load, and not being on antiretroviral therapy. HIV-positive ...
Medicine
Infection
93f4a1b7-d3d6-431e-b837-46e6d4b55c01
index finger infection spreads to -
Thenar space
Mid palmar space
Hypothenar space
Flexion space
0a
single
Ans. is 'a' i.e., Thenar space o Thenar space communicates w'ith the index finger while the mid palmar space communicates with the middle, ring and little fingers.o Thus infection of index finger leads to thenar space infection while the infection of middle, ring or little finger leads to mid palmar space infection.Fea...
Orthopaedics
Management In Orthopedics
b28caa9b-0ae8-4ea2-addf-76fc73e080ab
Acute appendicitis is best diagnosed by -
History
Physical examination
X-ray abdomen
Ba meal
1b
single
null
Medicine
null
d0165435-9190-451d-999f-8e8e0596b44b
All are clinical features of chalcosis except
Kayser - Fleischer ring
Sun - flower cataract
Deposition of golden plaques at the posterior pole
Dalen- fuch's nodules.
3d
multi
Dalen - fuch's nodules are formed due to proliferation of the pigment epithelium ----- sympathetic ophthalmitis.
Ophthalmology
null
e78e2365-89f3-427d-a951-82876bf39f99
Bidextrous grip is seen at what age?
4 months
5 months
6 months
7 months
0a
single
Ans. A. 4 monthsFINE MOTOR MILESTONES: AgeMilestone4 monthsBidextrous reach6 monthsUnidextrous reach9 monthsImmature pincer grasp12monthsMature pincer grasp15monthsImitates scribbling, tower of 2 blocks18monthsScribbles, tower of 3 blocks2 yearsTower of 6 blocks, veical & circular stroke3 yearsTower of 9 blocks, copies...
Pediatrics
null
8dc0e2f2-b982-457b-a5eb-512c51653fb5
A victim of Tsunami has difficulty in overcoming the experience. She still recollects the happening in dreams and thoughts. The most likely diagnosis is
Post traumatic stress disorder
Conversion disorder
Panic disorder
Phobia
0a
single
PTSD is characterised by recurrent and intrusive recollections of the stressful event, either in flashbacks (images, thoughts, or perceptions) and/or in dreams. There is an associated sense of re-experiencing of the stressful event. There is marked avoidance of the events or situations that arouse recollections of the ...
Psychiatry
Anxiety disorders stress disorders and grief
82f52bd9-9d86-4880-bd37-5e126fc39c3f
A tumor has the following characteristic retrobulbar location within the muscle cone, well defined capsule, presents with slowly progressive proptosis, easily resectable, occurs most commonly in the 2nd to 4th decade. Most likely diagnosis is -
Capillary hemangioma
Cavernous hemangioma
Lymhangioma
Hemangiopericytome
1b
single
Ref: Clinical ophthalmology 5th/e p.670 *Cavernous hemangioma is the most common benign, intraconal tumor in adults. *Hemangiopericytoma is also retrobulbar intraconal lesion found in adults but is a rare tumor. Moreover owing to its tendency to invade the adjacent tissues, its margins are less distinct than cavernous ...
Ophthalmology
Diseases of orbit, Lids and lacrimal apparatus
eca703b2-c8ec-4ddf-9185-3408795e9219
For Status epilepticus, treatment of choice is: September 2012
Ethosuximide
Sodium valproate
Lamotrigine
Lorazepam
3d
single
Ans. D i.e. Lorazepam
Medicine
null
5e886651-1eb4-4a2b-9708-86ad0d2df14c
All are subjective tests for audiometry except:
Tone decay
Impedance audiometry
Speech audiometry
Pure tone audiometry
1b
multi
(b) Impedance audiometry(Ref. Scott Brown, 6th ed., Vol 2; 2/12/1)Impedance audiometry is an objective test. It does not require the cooperation of patient.Other objective audiometry tests are; OAEs, Electrocochleography and BERA
ENT
Hearing Loss
564f1c25-6740-4039-b44e-67676960268f
The mesial surface of the crown is almost parallel to long axis and the root of a:
Maxillary 1st premolar
Mandibular 2nd Premolar
Maxillary canine
Mandibular canine
3d
multi
null
Dental
null
2e4474c3-a6a1-4ac7-b7f1-29d595a093b1
Tonic neck relfex is lost in lesion of -
Cerebral coex
Midbrain
Medulla
Spinal cord
2c
single
Ans. is 'c' i.e., Medulla
Physiology
null
b54af3d2-b60d-4f99-9ea6-bffc15fe5cc0
More than 90% patients of CREST syndrome with the limited cutaneous form of this disorder make which of the following autoantibodies?
Anti-centromere
Anti-DNA topoisomerase l
Anti-double-stranded DNA
Anti-Golgi
0a
single
All forms of scleroderma are thought to have a strong autoimmune component, and glucocoicoids and azathioprine are used to suppress the inflammatory complications of scleroderma. (Other drugs that can be used in therapy include penicillamine, which inhibits collagen cross-linking, NSAIDS for pain, and ACE inhibitors to...
Pathology
null
d3ce95e3-cc52-483b-9ef1-7004bd2bc26e
Name of mumps vaccine is
Jeryl Lynn
Edmonshon Zagreb
Schwatz
Moraten
0a
single
Widely used live attenuated mumps vaccine include the jeryl Lynn, RIT 4385, Leningrad-3, L-Zagreb and Urable strains. The current mumps strain (jeryl Lynn) has the lowest associated incidence of post-vaccine aseptic meningitis.
Social & Preventive Medicine
Epidemiology
d5d04e58-c79f-4cd8-a16a-86957e7e0352
Sacro-Iliac joint involvement is common in which condition?
Ankylosing spondylitis
Rheumatoid arthritis
Reiter's syndrome
Osteoarthritis
0a
single
(A) Ankylosing spondylitis # ANKYLOSING SPONDYLITIS (AS, from Greek ankylos, crooked; spondylos, vertebrae; -itis, inflammation), previously known as Bekhterev's disease, Bekhterev syndrome, and Marie-Strumpell disease, is a chronic inflammatory disease of the axial skeleton with variable involvement of peripheral join...
Orthopaedics
Miscellaneous
df6a272b-7829-430a-8a33-e4699311c2f7
Infertility issues with leiomyoma can be addressed by
Combined oral contraceptive pills
DMPA
GnRH agonist
Ulipristal
2c
single
GnRH agonist treatment is approved for treating infertility associated with fibroid uterus.
Gynaecology & Obstetrics
null
55c0de7e-7d82-443c-94a9-f92be029d521
An adult male sustained accidental burns and died 1 hour later. Which of the following enzymes will be increased in the burn area?
ATPase
Aminopeptidase
Acid phosphatase
Alkaline phosphatase
0a
single
Answer: a) ATPase (KS NARAYAN REDDY 33rd ED P-327)In antemortem burns, skin adjacent to the burnt area will show increase in the following enzymes after certain time intervalEnzymeAge of wounds (hour)ATPases1Esterases1Aminopeptidases2Acid phosphatase4Alkaline phosphatase8
Forensic Medicine
Injuries
71486f22-c9b4-4b95-aafb-bdc9ac5e5ac6
Recommended daily dietary requirment of folate (folic acid) in children ?
80-120 mg
200 mg
400 mg
600 mg
0a
single
Ans. is 'a' i.e., 80-120 mg Recommended daily allowances of folic acid are:- Healthy adults - 200 micro gm.(mcg) Pregnancy - 500 mcg Lactation - 300 mcg Children - 80-120 mcg
Social & Preventive Medicine
null
80dc11de-9ef9-4971-b7d2-a32de25dd7b0
Alcohol dependence is seen which of the following phase
Oral
Phallic
Anal
Latency
0a
multi
Ans. is 'a' i.e. Oral PhasePsychiatric disorders resulting from fixation of regression to this phase* Oral phase (Birth 1 Vx year)* Alcohol dependence or drug dependence* Severe mood disorder* Dependent personality traits and disorders* Schizophrenia* Ana! phase* Obsessive compulsive traits* Obsessive compulsive disord...
Psychiatry
Substance Abuse
85ee024c-012e-4424-90f1-e37da3395ab2
CAMP acts through:
Activation of protein kinase
Activation of adenylate cyclase
Ca2+ release.
All
0a
multi
A i.e., Activation of protein kinase
Physiology
null
9dd73ab3-16bc-4abf-aa0c-a2092461ec54
A four-fold increase in the titre obtained in Weil- Felix reaction is diagnostic of -
Rickettsial infection
Fungal infection
Spirochetal infection
Viral infection
0a
single
In weil-felix test, host antibodies to various rickettsial species cause agglutination of Proteus bacteria because they cross-react with bacterial cell surface antigens. Reference: Harrison20th edition pg 1011
Medicine
Infection
2907ab39-83ce-40d9-8be0-fbea58bfffe0
The diameter of Tricuspid orifice is
2cm
2.5cm
3cm
4cm
3d
single
ValveDiameter of OrificePulmonary2.5cmAoic2.5cmMitral3cmTricuspid4cmRef: BD Chaurasia; Volume 1; 6th edition; Table 18.1
Anatomy
Thorax
656853e5-84ee-4e79-bdb7-9eab31cda926
Most common cause of hirsutism in a teenage girl:
Ovarian disease
Pheochromocytoma
Obesity
Adrenogenital syndrome
0a
single
As explained earlier PCOD is the most common cause of hirsutism. PCOD most common affects teenage girls (15–25 years). Therefore, In teenage girls most common cause of hirsutism is PCOD.
Gynaecology & Obstetrics
null
71c1c672-d240-46ee-a51f-1012f7a35ec1
CSF is stored at:Kerala 11
4degC
-20degC
Room temperature
-70degC
0a
single
Ans. 4degC
Forensic Medicine
null
0ceaea9e-c661-46de-b56e-36a9773829d4
Gastrosplenic ligament is derived from?
Splenic artery
Splenic vein
Dorsal mesogastrium
Ventral mesogastrium
2c
single
ANSWER: (C) Dorsal mesogastriumREF: Langman's Medical Embryology 9th edition 293The gastrosplenic ligament (ligamentum gastrosplenicum or gastrolienal ligament) is part of the greater omentum. Embryonically the gastrosplenic ligament is derived from the dorsal mesogastrium. The gastrosplenic ligament is made of periton...
Anatomy
Abdomen & Pelvis
88524b08-bbae-42ef-9cc8-35ea7d85a948
A 59-year-old male is found to have a 3.5-cm mass in the right upper lobe of his lung. A biopsy of this mass is diagnosed as a moderately differentiated squamous cell carcinoma. Workup reveals that no bone metastases are present, but laboratory examination reveals that the man's serum calcium levels are 11.5 mg/dL. Thi...
Parathyroid hormone
Calcitonin
Parathyroid hormone-related peptide
Calcitonin-related peptide
2c
single
Symptoms not caused by either local or metastatic effects of tumors are called paraneoplastic syndromes. Bronchogenic carcinomas are associated with the development of many different types of paraneoplastic syndromes. These syndromes are usually associated with the secretion of ceain substances by the tumor cells. For ...
Pathology
miscellaneous
a2593ea3-4ab0-4355-b501-29349059e474
Crossing over, true is;
Occurs during diplotene stage
Between non sister chromatids of homologous chromosomes
Between sister chromatids of homologous chromosomes
Between non homologous chromosomes sister chromatids
1b
multi
Crossing over is the exchange of genetic material between non sister chromatids of homologous chromosomes occuring during pachytene stage of prophase I of meiosis.Recombination of genes in the same chromosome is brought about by crossing over. Ref: PRINCIPLES OF GENETICS, By Eldon John Gardner, Michael J. Simmons, D. P...
Biochemistry
null
da799290-f6ea-4520-a731-f3b40e6de7e6
Bloom Richardson grading -
Carcinoma breast
Carcinoma lung
Carcinoma prostate
Cercinoma ovary
0a
single
Ans. is 'a' i.e., Carcinoma breasto Bloom Richardson Grading and its variants are used to grade breast cancers.
Pathology
Breast
a1c3aa81-681e-4a77-b2e4-0ac271869746
Which among the following is FALSE about congenital toxoplasmosis?
IgA is better than IgM in detection
Diagnosed by detection of IgM in cord blood
IgG is diagnostic
Not recalled
2c
multi
Negative IgM with positive IgG indicates past infection. The presence of IgM antibody (which does not cross placenta) in the infant's circulation will diagnose congenital toxoplasmosis. The double sandwich IgA-ELISA is more sensitive than the IgM-ELISA for detecting congenital infection in the fetus and newborn. The me...
Microbiology
null
2f982a95-4801-4c7b-b40b-3e6e6bdfa0b6
Superior suprarenal aery originates from:
Abdominal aoa
Renal aery
Inferior phrenic aery
Splenic aery
2c
single
Inferior phrenic aery
Anatomy
null